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Network neighborhood for query Sequence : CBX4_MOUSE

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CBX4_MOUSE
SwissProt Accessions	O55187	Gene names	Cbx4, Pc2
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (mPc2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CBX4_HUMAN
θ value	0 (rank : 1)	NC score	0.989719 (rank : 2)
Query Neighborhood Hits	64	Target Neighborhood Hits	68	Shared Neighborhood Hits	39
SwissProt Accessions	O00257, Q96C04	Gene names	CBX4
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (hPc2).

CBX4_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	64	Target Neighborhood Hits	64	Shared Neighborhood Hits	64
SwissProt Accessions	O55187	Gene names	Cbx4, Pc2
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (mPc2).

CBX7_HUMAN
θ value	2.19584e-30 (rank : 3)	NC score	0.893574 (rank : 4)
Query Neighborhood Hits	64	Target Neighborhood Hits	48	Shared Neighborhood Hits	32
SwissProt Accessions	O95931, Q86T17	Gene names	CBX7
Domain Architecture
Description	Chromobox protein homolog 7.

CBX7_MOUSE
θ value	3.74554e-30 (rank : 4)	NC score	0.913482 (rank : 3)
Query Neighborhood Hits	64	Target Neighborhood Hits	38	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VDS3	Gene names	Cbx7, D15Ertd417e
Domain Architecture
Description	Chromobox protein homolog 7.

CBX8_HUMAN
θ value	5.97985e-28 (rank : 5)	NC score	0.847396 (rank : 7)
Query Neighborhood Hits	64	Target Neighborhood Hits	67	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HC52, Q96H39, Q9NR07	Gene names	CBX8, PC3, RC1
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1).

CBX8_MOUSE
θ value	7.80994e-28 (rank : 6)	NC score	0.850514 (rank : 5)
Query Neighborhood Hits	64	Target Neighborhood Hits	46	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QXV1	Gene names	Cbx8, Pc3
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (mPc3).

CBX6_HUMAN
θ value	1.02001e-27 (rank : 7)	NC score	0.840305 (rank : 8)
Query Neighborhood Hits	64	Target Neighborhood Hits	104	Shared Neighborhood Hits	33
SwissProt Accessions	O95503, Q96EM5	Gene names	CBX6
Domain Architecture
Description	Chromobox protein homolog 6.

CBX6_MOUSE
θ value	1.02001e-27 (rank : 8)	NC score	0.849880 (rank : 6)
Query Neighborhood Hits	64	Target Neighborhood Hits	50	Shared Neighborhood Hits	32
SwissProt Accessions	Q9DBY5, Q8BZH5	Gene names	Cbx6
Domain Architecture
Description	Chromobox protein homolog 6.

CBX2_MOUSE
θ value	8.93572e-24 (rank : 9)	NC score	0.801622 (rank : 9)
Query Neighborhood Hits	64	Target Neighborhood Hits	119	Shared Neighborhood Hits	34
SwissProt Accessions	P30658, O35731, Q8CIA0	Gene names	Cbx2, M33
Domain Architecture
Description	Chromobox protein homolog 2 (Modifier 3 protein) (M33).

CBX2_HUMAN
θ value	1.5242e-23 (rank : 10)	NC score	0.754212 (rank : 10)
Query Neighborhood Hits	64	Target Neighborhood Hits	264	Shared Neighborhood Hits	36
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

CBX5_HUMAN
θ value	4.76016e-09 (rank : 11)	NC score	0.628282 (rank : 13)
Query Neighborhood Hits	64	Target Neighborhood Hits	70	Shared Neighborhood Hits	30
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CBX5_MOUSE
θ value	8.11959e-09 (rank : 12)	NC score	0.627855 (rank : 14)
Query Neighborhood Hits	64	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

CBX1_HUMAN
θ value	1.06045e-08 (rank : 13)	NC score	0.634920 (rank : 11)
Query Neighborhood Hits	64	Target Neighborhood Hits	44	Shared Neighborhood Hits	30
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
θ value	1.06045e-08 (rank : 14)	NC score	0.634920 (rank : 12)
Query Neighborhood Hits	64	Target Neighborhood Hits	44	Shared Neighborhood Hits	30
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

CBX3_HUMAN
θ value	1.38499e-08 (rank : 15)	NC score	0.619089 (rank : 15)
Query Neighborhood Hits	64	Target Neighborhood Hits	36	Shared Neighborhood Hits	30
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

CBX3_MOUSE
θ value	6.87365e-08 (rank : 16)	NC score	0.606839 (rank : 16)
Query Neighborhood Hits	64	Target Neighborhood Hits	39	Shared Neighborhood Hits	30
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

CDYL_MOUSE
θ value	5.81887e-07 (rank : 17)	NC score	0.394049 (rank : 17)
Query Neighborhood Hits	64	Target Neighborhood Hits	69	Shared Neighborhood Hits	31
SwissProt Accessions	Q9WTK2	Gene names	Cdyl
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

CDYL1_HUMAN
θ value	2.44474e-05 (rank : 18)	NC score	0.383927 (rank : 18)
Query Neighborhood Hits	64	Target Neighborhood Hits	92	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y232	Gene names	CDYL, CDYL1
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

SUV92_MOUSE
θ value	3.19293e-05 (rank : 19)	NC score	0.331228 (rank : 22)
Query Neighborhood Hits	64	Target Neighborhood Hits	59	Shared Neighborhood Hits	29
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

MPP8_HUMAN
θ value	9.29e-05 (rank : 20)	NC score	0.217162 (rank : 26)
Query Neighborhood Hits	64	Target Neighborhood Hits	948	Shared Neighborhood Hits	40
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

SUV92_HUMAN
θ value	9.29e-05 (rank : 21)	NC score	0.312888 (rank : 23)
Query Neighborhood Hits	64	Target Neighborhood Hits	54	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

CDY1_HUMAN
θ value	0.000121331 (rank : 22)	NC score	0.365060 (rank : 21)
Query Neighborhood Hits	64	Target Neighborhood Hits	48	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y6F8, O14600	Gene names	CDY1
Domain Architecture
Description	Testis-specific chromodomain protein Y 1.

CDY2_HUMAN
θ value	0.000121331 (rank : 23)	NC score	0.365787 (rank : 20)
Query Neighborhood Hits	64	Target Neighborhood Hits	49	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y6F7	Gene names	CDY2A, CDY2
Domain Architecture
Description	Testis-specific chromodomain protein Y 2.

CHD1_HUMAN
θ value	0.000158464 (rank : 24)	NC score	0.161317 (rank : 27)
Query Neighborhood Hits	64	Target Neighborhood Hits	337	Shared Neighborhood Hits	36
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

SUV91_MOUSE
θ value	0.00035302 (rank : 25)	NC score	0.309889 (rank : 24)
Query Neighborhood Hits	64	Target Neighborhood Hits	69	Shared Neighborhood Hits	29
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

CDYL2_HUMAN
θ value	0.000461057 (rank : 26)	NC score	0.377558 (rank : 19)
Query Neighborhood Hits	64	Target Neighborhood Hits	53	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N8U2	Gene names	CDYL2
Domain Architecture
Description	Chromodomain Y-like protein 2 (CDY-like 2).

CHD1_MOUSE
θ value	0.000461057 (rank : 27)	NC score	0.158707 (rank : 28)
Query Neighborhood Hits	64	Target Neighborhood Hits	266	Shared Neighborhood Hits	35
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

SUV91_HUMAN
θ value	0.00175202 (rank : 28)	NC score	0.287744 (rank : 25)
Query Neighborhood Hits	64	Target Neighborhood Hits	63	Shared Neighborhood Hits	30
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

CHD2_HUMAN
θ value	0.00228821 (rank : 29)	NC score	0.149472 (rank : 29)
Query Neighborhood Hits	64	Target Neighborhood Hits	360	Shared Neighborhood Hits	34
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

NFH_MOUSE
θ value	0.0113563 (rank : 30)	NC score	0.030893 (rank : 53)
Query Neighborhood Hits	64	Target Neighborhood Hits	2247	Shared Neighborhood Hits	25
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

BRD4_MOUSE
θ value	0.0563607 (rank : 31)	NC score	0.049976 (rank : 45)
Query Neighborhood Hits	64	Target Neighborhood Hits	845	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BRD4_HUMAN
θ value	0.0961366 (rank : 32)	NC score	0.051705 (rank : 43)
Query Neighborhood Hits	64	Target Neighborhood Hits	851	Shared Neighborhood Hits	14
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CEBPZ_HUMAN
θ value	0.279714 (rank : 33)	NC score	0.040964 (rank : 47)
Query Neighborhood Hits	64	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q03701, Q8NE75	Gene names	CEBPZ, CBF2
Domain Architecture
Description	CCAAT/enhancer-binding protein zeta (CCAAT-box-binding transcription factor) (CCAAT-binding factor) (CBF).

ARI1B_HUMAN
θ value	0.47712 (rank : 34)	NC score	0.034396 (rank : 49)
Query Neighborhood Hits	64	Target Neighborhood Hits	567	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

RAI1_MOUSE
θ value	0.47712 (rank : 35)	NC score	0.042114 (rank : 46)
Query Neighborhood Hits	64	Target Neighborhood Hits	344	Shared Neighborhood Hits	7
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

CAD15_MOUSE
θ value	0.813845 (rank : 36)	NC score	0.005938 (rank : 71)
Query Neighborhood Hits	64	Target Neighborhood Hits	169	Shared Neighborhood Hits	2
SwissProt Accessions	P33146, Q9QYZ7	Gene names	Cdh15, Cdh14
Domain Architecture
Description	Cadherin-15 precursor (Muscle-cadherin) (M-cadherin) (Cadherin-14).

RP1L1_MOUSE
θ value	0.813845 (rank : 37)	NC score	0.027069 (rank : 54)
Query Neighborhood Hits	64	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

CSKI2_HUMAN
θ value	1.06291 (rank : 38)	NC score	0.016594 (rank : 60)
Query Neighborhood Hits	64	Target Neighborhood Hits	747	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

RAI1_HUMAN
θ value	1.38821 (rank : 39)	NC score	0.040563 (rank : 48)
Query Neighborhood Hits	64	Target Neighborhood Hits	360	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

ARI4A_HUMAN
θ value	1.81305 (rank : 40)	NC score	0.063761 (rank : 38)
Query Neighborhood Hits	64	Target Neighborhood Hits	434	Shared Neighborhood Hits	17
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

EP300_HUMAN
θ value	1.81305 (rank : 41)	NC score	0.023572 (rank : 56)
Query Neighborhood Hits	64	Target Neighborhood Hits	821	Shared Neighborhood Hits	10
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

OGFR_HUMAN
θ value	1.81305 (rank : 42)	NC score	0.031471 (rank : 52)
Query Neighborhood Hits	64	Target Neighborhood Hits	1582	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

ARX_MOUSE
θ value	2.36792 (rank : 43)	NC score	0.007209 (rank : 69)
Query Neighborhood Hits	64	Target Neighborhood Hits	398	Shared Neighborhood Hits	4
SwissProt Accessions	O35085, Q9QYT4	Gene names	Arx
Domain Architecture
Description	Homeobox protein ARX (Aristaless-related homeobox).

BMX_HUMAN
θ value	2.36792 (rank : 44)	NC score	-0.000989 (rank : 73)
Query Neighborhood Hits	64	Target Neighborhood Hits	942	Shared Neighborhood Hits	4
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

K0195_HUMAN
θ value	2.36792 (rank : 45)	NC score	0.026858 (rank : 55)
Query Neighborhood Hits	64	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	Q12767, O75536, Q86XF1	Gene names	KIAA0195, TMEM94
Domain Architecture	No domain graphic available
Description	Protein KIAA0195 (Transmembrane protein 94).

KIF1C_HUMAN
θ value	2.36792 (rank : 46)	NC score	0.008269 (rank : 68)
Query Neighborhood Hits	64	Target Neighborhood Hits	128	Shared Neighborhood Hits	4
SwissProt Accessions	O43896, O75186	Gene names	KIF1C, KIAA0706
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF1C.

LCOR_HUMAN
θ value	3.0926 (rank : 47)	NC score	0.033085 (rank : 50)
Query Neighborhood Hits	64	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q96JN0, Q5VW16, Q7Z723, Q86T32, Q86T33, Q8N3L6	Gene names	LCOR, KIAA1795, MLR2
Domain Architecture	No domain graphic available
Description	Ligand-dependent corepressor (LCoR) (Mblk1-related protein 2).

LCOR_MOUSE
θ value	3.0926 (rank : 48)	NC score	0.033046 (rank : 51)
Query Neighborhood Hits	64	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZPI3, Q3U302, Q5CZW7, Q80VA8, Q8BGT2, Q8C9Q0	Gene names	Lcor, Kiaa1795, Mlr2
Domain Architecture	No domain graphic available
Description	Ligand-dependent corepressor (LCoR) (Mblk1-related protein 2).

ANKS1_MOUSE
θ value	4.03905 (rank : 49)	NC score	0.009914 (rank : 67)
Query Neighborhood Hits	64	Target Neighborhood Hits	453	Shared Neighborhood Hits	6
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ARX_HUMAN
θ value	4.03905 (rank : 50)	NC score	0.006115 (rank : 70)
Query Neighborhood Hits	64	Target Neighborhood Hits	401	Shared Neighborhood Hits	4
SwissProt Accessions	Q96QS3	Gene names	ARX
Domain Architecture
Description	Homeobox protein ARX (Aristaless-related homeobox).

DEND_HUMAN
θ value	4.03905 (rank : 51)	NC score	0.021379 (rank : 58)
Query Neighborhood Hits	64	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	O94850	Gene names	DDN, KIAA0749
Domain Architecture	No domain graphic available
Description	Dendrin.

CHD3_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.068628 (rank : 35)
Query Neighborhood Hits	64	Target Neighborhood Hits	397	Shared Neighborhood Hits	33
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

EVI1_MOUSE
θ value	5.27518 (rank : 53)	NC score	-0.002218 (rank : 74)
Query Neighborhood Hits	64	Target Neighborhood Hits	826	Shared Neighborhood Hits	3
SwissProt Accessions	P14404	Gene names	Evi1, Evi-1
Domain Architecture	No domain graphic available
Description	Ecotropic virus integration 1 site protein.

SRRM2_MOUSE
θ value	5.27518 (rank : 54)	NC score	0.015912 (rank : 62)
Query Neighborhood Hits	64	Target Neighborhood Hits	1470	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CTR9_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.011917 (rank : 64)
Query Neighborhood Hits	64	Target Neighborhood Hits	383	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

GPTC2_HUMAN
θ value	6.88961 (rank : 56)	NC score	0.011100 (rank : 65)
Query Neighborhood Hits	64	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NW75, Q86YE7	Gene names	GPATC2
Domain Architecture
Description	G patch domain-containing protein 2.

K0427_MOUSE
θ value	6.88961 (rank : 57)	NC score	0.021547 (rank : 57)
Query Neighborhood Hits	64	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PEE2	Gene names	Gm672
Domain Architecture	No domain graphic available
Description	Protein KIAA0427 homolog.

M4K4_HUMAN
θ value	6.88961 (rank : 58)	NC score	-0.003059 (rank : 75)
Query Neighborhood Hits	64	Target Neighborhood Hits	1589	Shared Neighborhood Hits	6
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MBB1A_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.017453 (rank : 59)
Query Neighborhood Hits	64	Target Neighborhood Hits	665	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MS3L1_MOUSE
θ value	6.88961 (rank : 60)	NC score	0.085615 (rank : 32)
Query Neighborhood Hits	64	Target Neighborhood Hits	67	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WVG9	Gene names	Msl3l1, Msl31
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

NKTR_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.013505 (rank : 63)
Query Neighborhood Hits	64	Target Neighborhood Hits	658	Shared Neighborhood Hits	17
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

S23IP_MOUSE
θ value	6.88961 (rank : 62)	NC score	0.016082 (rank : 61)
Query Neighborhood Hits	64	Target Neighborhood Hits	363	Shared Neighborhood Hits	9
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

SAV1_HUMAN
θ value	6.88961 (rank : 63)	NC score	0.010180 (rank : 66)
Query Neighborhood Hits	64	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

GRIP1_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.004135 (rank : 72)
Query Neighborhood Hits	64	Target Neighborhood Hits	231	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

AUHM_MOUSE
θ value	θ > 10 (rank : 65)	NC score	0.054692 (rank : 41)
Query Neighborhood Hits	64	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLZ3, Q80YD7, Q8QZS0, Q9CY78, Q9D155	Gene names	Auh
Domain Architecture
Description	Methylglutaconyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding enoyl-CoA hydratase) (muAUH).

AUMH_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.054097 (rank : 42)
Query Neighborhood Hits	64	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q13825, Q8WUE4	Gene names	AUH
Domain Architecture
Description	Methylglutaconyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding protein/enoyl-CoA hydratase).

CHD4_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.055160 (rank : 40)
Query Neighborhood Hits	64	Target Neighborhood Hits	365	Shared Neighborhood Hits	24
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.055926 (rank : 39)
Query Neighborhood Hits	64	Target Neighborhood Hits	408	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD5_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.051576 (rank : 44)
Query Neighborhood Hits	64	Target Neighborhood Hits	349	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

ECH1_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.068920 (rank : 34)
Query Neighborhood Hits	64	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q13011, Q8WVX0, Q96EZ9	Gene names	ECH1
Domain Architecture
Description	Delta3,5-delta2,4-dienoyl-CoA isomerase, mitochondrial precursor (EC 5.3.3.-).

ECH1_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.071036 (rank : 33)
Query Neighborhood Hits	64	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	O35459, Q5M8P6	Gene names	Ech1
Domain Architecture
Description	Delta3,5-delta2,4-dienoyl-CoA isomerase, mitochondrial precursor (EC 5.3.3.-).

ECHM_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.066841 (rank : 37)
Query Neighborhood Hits	64	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	P30084, O00739, Q5VWY1, Q96H54	Gene names	ECHS1
Domain Architecture
Description	Enoyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.17) (Short chain enoyl-CoA hydratase) (SCEH) (Enoyl-CoA hydratase 1).

ECHM_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.067253 (rank : 36)
Query Neighborhood Hits	64	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BH95, Q3TJK2, Q6GQS2, Q6PEN1, Q99LX7	Gene names	Echs1
Domain Architecture	No domain graphic available
Description	Enoyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.17) (Short chain enoyl-CoA hydratase) (SCEH) (Enoyl-CoA hydratase 1).

PECI_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.102845 (rank : 30)
Query Neighborhood Hits	64	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	O75521, Q5JYK5, Q8N0X0, Q9BUE9, Q9H0T9, Q9NQH1, Q9NYH7, Q9UN55	Gene names	PECI, DRS1, HCA88
Domain Architecture
Description	Peroxisomal 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (Dodecenoyl-CoA isomerase) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (DBI-related protein 1) (DRS-1) (Hepatocellular carcinoma- associated antigen 88) (NY-REN-1 antigen).

PECI_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.102232 (rank : 31)
Query Neighborhood Hits	64	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WUR2	Gene names	Peci
Domain Architecture
Description	Peroxisomal 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (Dodecenoyl-CoA isomerase) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase).

Hits sorted by NC score

CBX4_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	64	Target Neighborhood Hits	64	Shared Neighborhood Hits	64
SwissProt Accessions	O55187	Gene names	Cbx4, Pc2
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (mPc2).

CBX4_HUMAN
NC score	0.989719 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	64	Target Neighborhood Hits	68	Shared Neighborhood Hits	39
SwissProt Accessions	O00257, Q96C04	Gene names	CBX4
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (hPc2).

CBX7_MOUSE
NC score	0.913482 (rank : 3)	θ value	3.74554e-30 (rank : 4)
Query Neighborhood Hits	64	Target Neighborhood Hits	38	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VDS3	Gene names	Cbx7, D15Ertd417e
Domain Architecture
Description	Chromobox protein homolog 7.

CBX7_HUMAN
NC score	0.893574 (rank : 4)	θ value	2.19584e-30 (rank : 3)
Query Neighborhood Hits	64	Target Neighborhood Hits	48	Shared Neighborhood Hits	32
SwissProt Accessions	O95931, Q86T17	Gene names	CBX7
Domain Architecture
Description	Chromobox protein homolog 7.

CBX8_MOUSE
NC score	0.850514 (rank : 5)	θ value	7.80994e-28 (rank : 6)
Query Neighborhood Hits	64	Target Neighborhood Hits	46	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QXV1	Gene names	Cbx8, Pc3
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (mPc3).

CBX6_MOUSE
NC score	0.849880 (rank : 6)	θ value	1.02001e-27 (rank : 8)
Query Neighborhood Hits	64	Target Neighborhood Hits	50	Shared Neighborhood Hits	32
SwissProt Accessions	Q9DBY5, Q8BZH5	Gene names	Cbx6
Domain Architecture
Description	Chromobox protein homolog 6.

CBX8_HUMAN
NC score	0.847396 (rank : 7)	θ value	5.97985e-28 (rank : 5)
Query Neighborhood Hits	64	Target Neighborhood Hits	67	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HC52, Q96H39, Q9NR07	Gene names	CBX8, PC3, RC1
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1).

CBX6_HUMAN
NC score	0.840305 (rank : 8)	θ value	1.02001e-27 (rank : 7)
Query Neighborhood Hits	64	Target Neighborhood Hits	104	Shared Neighborhood Hits	33
SwissProt Accessions	O95503, Q96EM5	Gene names	CBX6
Domain Architecture
Description	Chromobox protein homolog 6.

CBX2_MOUSE
NC score	0.801622 (rank : 9)	θ value	8.93572e-24 (rank : 9)
Query Neighborhood Hits	64	Target Neighborhood Hits	119	Shared Neighborhood Hits	34
SwissProt Accessions	P30658, O35731, Q8CIA0	Gene names	Cbx2, M33
Domain Architecture
Description	Chromobox protein homolog 2 (Modifier 3 protein) (M33).

CBX2_HUMAN
NC score	0.754212 (rank : 10)	θ value	1.5242e-23 (rank : 10)
Query Neighborhood Hits	64	Target Neighborhood Hits	264	Shared Neighborhood Hits	36
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

CBX1_HUMAN
NC score	0.634920 (rank : 11)	θ value	1.06045e-08 (rank : 13)
Query Neighborhood Hits	64	Target Neighborhood Hits	44	Shared Neighborhood Hits	30
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
NC score	0.634920 (rank : 12)	θ value	1.06045e-08 (rank : 14)
Query Neighborhood Hits	64	Target Neighborhood Hits	44	Shared Neighborhood Hits	30
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

CBX5_HUMAN
NC score	0.628282 (rank : 13)	θ value	4.76016e-09 (rank : 11)
Query Neighborhood Hits	64	Target Neighborhood Hits	70	Shared Neighborhood Hits	30
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CBX5_MOUSE
NC score	0.627855 (rank : 14)	θ value	8.11959e-09 (rank : 12)
Query Neighborhood Hits	64	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

CBX3_HUMAN
NC score	0.619089 (rank : 15)	θ value	1.38499e-08 (rank : 15)
Query Neighborhood Hits	64	Target Neighborhood Hits	36	Shared Neighborhood Hits	30
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

CBX3_MOUSE
NC score	0.606839 (rank : 16)	θ value	6.87365e-08 (rank : 16)
Query Neighborhood Hits	64	Target Neighborhood Hits	39	Shared Neighborhood Hits	30
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

CDYL_MOUSE
NC score	0.394049 (rank : 17)	θ value	5.81887e-07 (rank : 17)
Query Neighborhood Hits	64	Target Neighborhood Hits	69	Shared Neighborhood Hits	31
SwissProt Accessions	Q9WTK2	Gene names	Cdyl
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

CDYL1_HUMAN
NC score	0.383927 (rank : 18)	θ value	2.44474e-05 (rank : 18)
Query Neighborhood Hits	64	Target Neighborhood Hits	92	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y232	Gene names	CDYL, CDYL1
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

CDYL2_HUMAN
NC score	0.377558 (rank : 19)	θ value	0.000461057 (rank : 26)
Query Neighborhood Hits	64	Target Neighborhood Hits	53	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N8U2	Gene names	CDYL2
Domain Architecture
Description	Chromodomain Y-like protein 2 (CDY-like 2).

CDY2_HUMAN
NC score	0.365787 (rank : 20)	θ value	0.000121331 (rank : 23)
Query Neighborhood Hits	64	Target Neighborhood Hits	49	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y6F7	Gene names	CDY2A, CDY2
Domain Architecture
Description	Testis-specific chromodomain protein Y 2.

CDY1_HUMAN
NC score	0.365060 (rank : 21)	θ value	0.000121331 (rank : 22)
Query Neighborhood Hits	64	Target Neighborhood Hits	48	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y6F8, O14600	Gene names	CDY1
Domain Architecture
Description	Testis-specific chromodomain protein Y 1.

SUV92_MOUSE
NC score	0.331228 (rank : 22)	θ value	3.19293e-05 (rank : 19)
Query Neighborhood Hits	64	Target Neighborhood Hits	59	Shared Neighborhood Hits	29
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV92_HUMAN
NC score	0.312888 (rank : 23)	θ value	9.29e-05 (rank : 21)
Query Neighborhood Hits	64	Target Neighborhood Hits	54	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV91_MOUSE
NC score	0.309889 (rank : 24)	θ value	0.00035302 (rank : 25)
Query Neighborhood Hits	64	Target Neighborhood Hits	69	Shared Neighborhood Hits	29
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

SUV91_HUMAN
NC score	0.287744 (rank : 25)	θ value	0.00175202 (rank : 28)
Query Neighborhood Hits	64	Target Neighborhood Hits	63	Shared Neighborhood Hits	30
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

MPP8_HUMAN
NC score	0.217162 (rank : 26)	θ value	9.29e-05 (rank : 20)
Query Neighborhood Hits	64	Target Neighborhood Hits	948	Shared Neighborhood Hits	40
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

CHD1_HUMAN
NC score	0.161317 (rank : 27)	θ value	0.000158464 (rank : 24)
Query Neighborhood Hits	64	Target Neighborhood Hits	337	Shared Neighborhood Hits	36
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_MOUSE
NC score	0.158707 (rank : 28)	θ value	0.000461057 (rank : 27)
Query Neighborhood Hits	64	Target Neighborhood Hits	266	Shared Neighborhood Hits	35
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD2_HUMAN
NC score	0.149472 (rank : 29)	θ value	0.00228821 (rank : 29)
Query Neighborhood Hits	64	Target Neighborhood Hits	360	Shared Neighborhood Hits	34
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

PECI_HUMAN
NC score	0.102845 (rank : 30)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	64	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	O75521, Q5JYK5, Q8N0X0, Q9BUE9, Q9H0T9, Q9NQH1, Q9NYH7, Q9UN55	Gene names	PECI, DRS1, HCA88
Domain Architecture
Description	Peroxisomal 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (Dodecenoyl-CoA isomerase) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (DBI-related protein 1) (DRS-1) (Hepatocellular carcinoma- associated antigen 88) (NY-REN-1 antigen).

PECI_MOUSE
NC score	0.102232 (rank : 31)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	64	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WUR2	Gene names	Peci
Domain Architecture
Description	Peroxisomal 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (Dodecenoyl-CoA isomerase) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase).

MS3L1_MOUSE
NC score	0.085615 (rank : 32)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	64	Target Neighborhood Hits	67	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WVG9	Gene names	Msl3l1, Msl31
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

ECH1_MOUSE
NC score	0.071036 (rank : 33)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	64	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	O35459, Q5M8P6	Gene names	Ech1
Domain Architecture
Description	Delta3,5-delta2,4-dienoyl-CoA isomerase, mitochondrial precursor (EC 5.3.3.-).

ECH1_HUMAN
NC score	0.068920 (rank : 34)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	64	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q13011, Q8WVX0, Q96EZ9	Gene names	ECH1
Domain Architecture
Description	Delta3,5-delta2,4-dienoyl-CoA isomerase, mitochondrial precursor (EC 5.3.3.-).

CHD3_HUMAN
NC score	0.068628 (rank : 35)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	64	Target Neighborhood Hits	397	Shared Neighborhood Hits	33
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

ECHM_MOUSE
NC score	0.067253 (rank : 36)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	64	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BH95, Q3TJK2, Q6GQS2, Q6PEN1, Q99LX7	Gene names	Echs1
Domain Architecture	No domain graphic available
Description	Enoyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.17) (Short chain enoyl-CoA hydratase) (SCEH) (Enoyl-CoA hydratase 1).

ECHM_HUMAN
NC score	0.066841 (rank : 37)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	64	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	P30084, O00739, Q5VWY1, Q96H54	Gene names	ECHS1
Domain Architecture
Description	Enoyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.17) (Short chain enoyl-CoA hydratase) (SCEH) (Enoyl-CoA hydratase 1).

ARI4A_HUMAN
NC score	0.063761 (rank : 38)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	64	Target Neighborhood Hits	434	Shared Neighborhood Hits	17
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

CHD4_MOUSE
NC score	0.055926 (rank : 39)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	64	Target Neighborhood Hits	408	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD4_HUMAN
NC score	0.055160 (rank : 40)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	64	Target Neighborhood Hits	365	Shared Neighborhood Hits	24
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

AUHM_MOUSE
NC score	0.054692 (rank : 41)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	64	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLZ3, Q80YD7, Q8QZS0, Q9CY78, Q9D155	Gene names	Auh
Domain Architecture
Description	Methylglutaconyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding enoyl-CoA hydratase) (muAUH).

AUMH_HUMAN
NC score	0.054097 (rank : 42)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	64	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q13825, Q8WUE4	Gene names	AUH
Domain Architecture
Description	Methylglutaconyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding protein/enoyl-CoA hydratase).

BRD4_HUMAN
NC score	0.051705 (rank : 43)	θ value	0.0961366 (rank : 32)
Query Neighborhood Hits	64	Target Neighborhood Hits	851	Shared Neighborhood Hits	14
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CHD5_HUMAN
NC score	0.051576 (rank : 44)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	64	Target Neighborhood Hits	349	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

BRD4_MOUSE
NC score	0.049976 (rank : 45)	θ value	0.0563607 (rank : 31)
Query Neighborhood Hits	64	Target Neighborhood Hits	845	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

RAI1_MOUSE
NC score	0.042114 (rank : 46)	θ value	0.47712 (rank : 35)
Query Neighborhood Hits	64	Target Neighborhood Hits	344	Shared Neighborhood Hits	7
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

CEBPZ_HUMAN
NC score	0.040964 (rank : 47)	θ value	0.279714 (rank : 33)
Query Neighborhood Hits	64	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q03701, Q8NE75	Gene names	CEBPZ, CBF2
Domain Architecture
Description	CCAAT/enhancer-binding protein zeta (CCAAT-box-binding transcription factor) (CCAAT-binding factor) (CBF).

RAI1_HUMAN
NC score	0.040563 (rank : 48)	θ value	1.38821 (rank : 39)
Query Neighborhood Hits	64	Target Neighborhood Hits	360	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

ARI1B_HUMAN
NC score	0.034396 (rank : 49)	θ value	0.47712 (rank : 34)
Query Neighborhood Hits	64	Target Neighborhood Hits	567	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

LCOR_HUMAN
NC score	0.033085 (rank : 50)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	64	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q96JN0, Q5VW16, Q7Z723, Q86T32, Q86T33, Q8N3L6	Gene names	LCOR, KIAA1795, MLR2
Domain Architecture	No domain graphic available
Description	Ligand-dependent corepressor (LCoR) (Mblk1-related protein 2).

LCOR_MOUSE
NC score	0.033046 (rank : 51)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	64	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZPI3, Q3U302, Q5CZW7, Q80VA8, Q8BGT2, Q8C9Q0	Gene names	Lcor, Kiaa1795, Mlr2
Domain Architecture	No domain graphic available
Description	Ligand-dependent corepressor (LCoR) (Mblk1-related protein 2).

OGFR_HUMAN
NC score	0.031471 (rank : 52)	θ value	1.81305 (rank : 42)
Query Neighborhood Hits	64	Target Neighborhood Hits	1582	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

NFH_MOUSE
NC score	0.030893 (rank : 53)	θ value	0.0113563 (rank : 30)
Query Neighborhood Hits	64	Target Neighborhood Hits	2247	Shared Neighborhood Hits	25
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RP1L1_MOUSE
NC score	0.027069 (rank : 54)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	64	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

K0195_HUMAN
NC score	0.026858 (rank : 55)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	64	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	Q12767, O75536, Q86XF1	Gene names	KIAA0195, TMEM94
Domain Architecture	No domain graphic available
Description	Protein KIAA0195 (Transmembrane protein 94).

EP300_HUMAN
NC score	0.023572 (rank : 56)	θ value	1.81305 (rank : 41)
Query Neighborhood Hits	64	Target Neighborhood Hits	821	Shared Neighborhood Hits	10
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

K0427_MOUSE
NC score	0.021547 (rank : 57)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	64	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PEE2	Gene names	Gm672
Domain Architecture	No domain graphic available
Description	Protein KIAA0427 homolog.

DEND_HUMAN
NC score	0.021379 (rank : 58)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	64	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	O94850	Gene names	DDN, KIAA0749
Domain Architecture	No domain graphic available
Description	Dendrin.

MBB1A_HUMAN
NC score	0.017453 (rank : 59)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	64	Target Neighborhood Hits	665	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

CSKI2_HUMAN
NC score	0.016594 (rank : 60)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	64	Target Neighborhood Hits	747	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

S23IP_MOUSE
NC score	0.016082 (rank : 61)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	64	Target Neighborhood Hits	363	Shared Neighborhood Hits	9
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

SRRM2_MOUSE
NC score	0.015912 (rank : 62)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	64	Target Neighborhood Hits	1470	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

NKTR_HUMAN
NC score	0.013505 (rank : 63)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	64	Target Neighborhood Hits	658	Shared Neighborhood Hits	17
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

CTR9_HUMAN
NC score	0.011917 (rank : 64)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	64	Target Neighborhood Hits	383	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

GPTC2_HUMAN
NC score	0.011100 (rank : 65)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	64	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NW75, Q86YE7	Gene names	GPATC2
Domain Architecture
Description	G patch domain-containing protein 2.

SAV1_HUMAN
NC score	0.010180 (rank : 66)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	64	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

ANKS1_MOUSE
NC score	0.009914 (rank : 67)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	64	Target Neighborhood Hits	453	Shared Neighborhood Hits	6
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

KIF1C_HUMAN
NC score	0.008269 (rank : 68)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	64	Target Neighborhood Hits	128	Shared Neighborhood Hits	4
SwissProt Accessions	O43896, O75186	Gene names	KIF1C, KIAA0706
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF1C.

ARX_MOUSE
NC score	0.007209 (rank : 69)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	64	Target Neighborhood Hits	398	Shared Neighborhood Hits	4
SwissProt Accessions	O35085, Q9QYT4	Gene names	Arx
Domain Architecture
Description	Homeobox protein ARX (Aristaless-related homeobox).

ARX_HUMAN
NC score	0.006115 (rank : 70)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	64	Target Neighborhood Hits	401	Shared Neighborhood Hits	4
SwissProt Accessions	Q96QS3	Gene names	ARX
Domain Architecture
Description	Homeobox protein ARX (Aristaless-related homeobox).

CAD15_MOUSE
NC score	0.005938 (rank : 71)	θ value	0.813845 (rank : 36)
Query Neighborhood Hits	64	Target Neighborhood Hits	169	Shared Neighborhood Hits	2
SwissProt Accessions	P33146, Q9QYZ7	Gene names	Cdh15, Cdh14
Domain Architecture
Description	Cadherin-15 precursor (Muscle-cadherin) (M-cadherin) (Cadherin-14).

GRIP1_HUMAN
NC score	0.004135 (rank : 72)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	64	Target Neighborhood Hits	231	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

BMX_HUMAN
NC score	-0.000989 (rank : 73)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	64	Target Neighborhood Hits	942	Shared Neighborhood Hits	4
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

EVI1_MOUSE
NC score	-0.002218 (rank : 74)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	64	Target Neighborhood Hits	826	Shared Neighborhood Hits	3
SwissProt Accessions	P14404	Gene names	Evi1, Evi-1
Domain Architecture	No domain graphic available
Description	Ecotropic virus integration 1 site protein.

M4K4_HUMAN
NC score	-0.003059 (rank : 75)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	64	Target Neighborhood Hits	1589	Shared Neighborhood Hits	6
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).