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Network neighborhood for query Sequence : DDX51_MOUSE

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DDX51_MOUSE
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DDX51_HUMAN
θ value	0 (rank : 1)	NC score	0.980622 (rank : 2)
Query Neighborhood Hits	130	Target Neighborhood Hits	332	Shared Neighborhood Hits	99
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX51_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	130	Target Neighborhood Hits	130	Shared Neighborhood Hits	130
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX27_MOUSE
θ value	8.02596e-49 (rank : 3)	NC score	0.951820 (rank : 3)
Query Neighborhood Hits	130	Target Neighborhood Hits	174	Shared Neighborhood Hits	87
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_HUMAN
θ value	1.51363e-47 (rank : 4)	NC score	0.950033 (rank : 4)
Query Neighborhood Hits	130	Target Neighborhood Hits	197	Shared Neighborhood Hits	88
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX49_HUMAN
θ value	3.05695e-40 (rank : 5)	NC score	0.946246 (rank : 8)
Query Neighborhood Hits	130	Target Neighborhood Hits	223	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX49_MOUSE
θ value	9.83387e-39 (rank : 6)	NC score	0.949340 (rank : 6)
Query Neighborhood Hits	130	Target Neighborhood Hits	119	Shared Neighborhood Hits	89
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX47_MOUSE
θ value	1.28434e-38 (rank : 7)	NC score	0.949452 (rank : 5)
Query Neighborhood Hits	130	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_HUMAN
θ value	6.37413e-38 (rank : 8)	NC score	0.948866 (rank : 7)
Query Neighborhood Hits	130	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX10_HUMAN
θ value	9.20422e-37 (rank : 9)	NC score	0.936157 (rank : 16)
Query Neighborhood Hits	130	Target Neighborhood Hits	210	Shared Neighborhood Hits	82
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX10_MOUSE
θ value	9.20422e-37 (rank : 10)	NC score	0.935411 (rank : 17)
Query Neighborhood Hits	130	Target Neighborhood Hits	233	Shared Neighborhood Hits	82
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX18_MOUSE
θ value	8.61488e-35 (rank : 11)	NC score	0.940998 (rank : 9)
Query Neighborhood Hits	130	Target Neighborhood Hits	115	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX18_HUMAN
θ value	1.12514e-34 (rank : 12)	NC score	0.938643 (rank : 15)
Query Neighborhood Hits	130	Target Neighborhood Hits	124	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX52_HUMAN
θ value	2.77131e-33 (rank : 13)	NC score	0.939372 (rank : 12)
Query Neighborhood Hits	130	Target Neighborhood Hits	107	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX52_MOUSE
θ value	6.17384e-33 (rank : 14)	NC score	0.939198 (rank : 13)
Query Neighborhood Hits	130	Target Neighborhood Hits	101	Shared Neighborhood Hits	89
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX21_MOUSE
θ value	5.22648e-32 (rank : 15)	NC score	0.906626 (rank : 54)
Query Neighborhood Hits	130	Target Neighborhood Hits	350	Shared Neighborhood Hits	94
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX55_HUMAN
θ value	5.22648e-32 (rank : 16)	NC score	0.939853 (rank : 11)
Query Neighborhood Hits	130	Target Neighborhood Hits	122	Shared Neighborhood Hits	85
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX55_MOUSE
θ value	5.22648e-32 (rank : 17)	NC score	0.940812 (rank : 10)
Query Neighborhood Hits	130	Target Neighborhood Hits	111	Shared Neighborhood Hits	87
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX21_HUMAN
θ value	2.86786e-30 (rank : 18)	NC score	0.912854 (rank : 45)
Query Neighborhood Hits	130	Target Neighborhood Hits	308	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX56_MOUSE
θ value	2.86786e-30 (rank : 19)	NC score	0.934517 (rank : 18)
Query Neighborhood Hits	130	Target Neighborhood Hits	87	Shared Neighborhood Hits	75
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX46_HUMAN
θ value	3.74554e-30 (rank : 20)	NC score	0.908991 (rank : 48)
Query Neighborhood Hits	130	Target Neighborhood Hits	357	Shared Neighborhood Hits	92
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
θ value	3.74554e-30 (rank : 21)	NC score	0.906806 (rank : 53)
Query Neighborhood Hits	130	Target Neighborhood Hits	358	Shared Neighborhood Hits	92
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX54_HUMAN
θ value	1.08979e-29 (rank : 22)	NC score	0.928695 (rank : 23)
Query Neighborhood Hits	130	Target Neighborhood Hits	170	Shared Neighborhood Hits	86
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX50_MOUSE
θ value	1.4233e-29 (rank : 23)	NC score	0.924309 (rank : 30)
Query Neighborhood Hits	130	Target Neighborhood Hits	137	Shared Neighborhood Hits	87
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_HUMAN
θ value	2.42779e-29 (rank : 24)	NC score	0.924335 (rank : 29)
Query Neighborhood Hits	130	Target Neighborhood Hits	132	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX56_HUMAN
θ value	2.42779e-29 (rank : 25)	NC score	0.934297 (rank : 19)
Query Neighborhood Hits	130	Target Neighborhood Hits	77	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DDX54_MOUSE
θ value	1.2049e-28 (rank : 26)	NC score	0.931806 (rank : 20)
Query Neighborhood Hits	130	Target Neighborhood Hits	124	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX41_MOUSE
θ value	3.50572e-28 (rank : 27)	NC score	0.929889 (rank : 22)
Query Neighborhood Hits	130	Target Neighborhood Hits	115	Shared Neighborhood Hits	88
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX41_HUMAN
θ value	4.57862e-28 (rank : 28)	NC score	0.930224 (rank : 21)
Query Neighborhood Hits	130	Target Neighborhood Hits	111	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX4_HUMAN
θ value	5.97985e-28 (rank : 29)	NC score	0.924852 (rank : 27)
Query Neighborhood Hits	130	Target Neighborhood Hits	123	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX23_HUMAN
θ value	1.02001e-27 (rank : 30)	NC score	0.900130 (rank : 61)
Query Neighborhood Hits	130	Target Neighborhood Hits	486	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX31_HUMAN
θ value	1.33217e-27 (rank : 31)	NC score	0.938950 (rank : 14)
Query Neighborhood Hits	130	Target Neighborhood Hits	132	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX43_HUMAN
θ value	5.06226e-27 (rank : 32)	NC score	0.923099 (rank : 32)
Query Neighborhood Hits	130	Target Neighborhood Hits	120	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX4_MOUSE
θ value	5.06226e-27 (rank : 33)	NC score	0.925476 (rank : 25)
Query Neighborhood Hits	130	Target Neighborhood Hits	100	Shared Neighborhood Hits	89
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX17_HUMAN
θ value	9.54697e-26 (rank : 34)	NC score	0.917237 (rank : 34)
Query Neighborhood Hits	130	Target Neighborhood Hits	104	Shared Neighborhood Hits	87
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX17_MOUSE
θ value	9.54697e-26 (rank : 35)	NC score	0.917395 (rank : 33)
Query Neighborhood Hits	130	Target Neighborhood Hits	105	Shared Neighborhood Hits	87
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX3X_HUMAN
θ value	8.93572e-24 (rank : 36)	NC score	0.908363 (rank : 49)
Query Neighborhood Hits	130	Target Neighborhood Hits	122	Shared Neighborhood Hits	90
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

PL10_MOUSE
θ value	1.99067e-23 (rank : 37)	NC score	0.908293 (rank : 51)
Query Neighborhood Hits	130	Target Neighborhood Hits	120	Shared Neighborhood Hits	88
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX6_MOUSE
θ value	2.59989e-23 (rank : 38)	NC score	0.924834 (rank : 28)
Query Neighborhood Hits	130	Target Neighborhood Hits	98	Shared Neighborhood Hits	87
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX24_HUMAN
θ value	4.43474e-23 (rank : 39)	NC score	0.914404 (rank : 37)
Query Neighborhood Hits	130	Target Neighborhood Hits	190	Shared Neighborhood Hits	87
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX39_HUMAN
θ value	4.43474e-23 (rank : 40)	NC score	0.915819 (rank : 36)
Query Neighborhood Hits	130	Target Neighborhood Hits	94	Shared Neighborhood Hits	86
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX3X_MOUSE
θ value	5.79196e-23 (rank : 41)	NC score	0.907278 (rank : 52)
Query Neighborhood Hits	130	Target Neighborhood Hits	117	Shared Neighborhood Hits	90
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX3Y_HUMAN
θ value	5.79196e-23 (rank : 42)	NC score	0.905536 (rank : 55)
Query Neighborhood Hits	130	Target Neighborhood Hits	121	Shared Neighborhood Hits	89
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX6_HUMAN
θ value	5.79196e-23 (rank : 43)	NC score	0.924940 (rank : 26)
Query Neighborhood Hits	130	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX24_MOUSE
θ value	1.6852e-22 (rank : 44)	NC score	0.916260 (rank : 35)
Query Neighborhood Hits	130	Target Neighborhood Hits	147	Shared Neighborhood Hits	87
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX3Y_MOUSE
θ value	2.20094e-22 (rank : 45)	NC score	0.908360 (rank : 50)
Query Neighborhood Hits	130	Target Neighborhood Hits	126	Shared Neighborhood Hits	88
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX1_MOUSE
θ value	2.87452e-22 (rank : 46)	NC score	0.867415 (rank : 67)
Query Neighborhood Hits	130	Target Neighborhood Hits	112	Shared Neighborhood Hits	83
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX28_HUMAN
θ value	2.87452e-22 (rank : 47)	NC score	0.923620 (rank : 31)
Query Neighborhood Hits	130	Target Neighborhood Hits	103	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX1_HUMAN
θ value	3.75424e-22 (rank : 48)	NC score	0.866039 (rank : 68)
Query Neighborhood Hits	130	Target Neighborhood Hits	110	Shared Neighborhood Hits	83
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

IF4A2_HUMAN
θ value	1.09232e-21 (rank : 49)	NC score	0.913113 (rank : 43)
Query Neighborhood Hits	130	Target Neighborhood Hits	102	Shared Neighborhood Hits	87
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
θ value	1.09232e-21 (rank : 50)	NC score	0.913113 (rank : 44)
Query Neighborhood Hits	130	Target Neighborhood Hits	102	Shared Neighborhood Hits	87
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

UAP56_HUMAN
θ value	1.09232e-21 (rank : 51)	NC score	0.913147 (rank : 41)
Query Neighborhood Hits	130	Target Neighborhood Hits	96	Shared Neighborhood Hits	85
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
θ value	1.09232e-21 (rank : 52)	NC score	0.913117 (rank : 42)
Query Neighborhood Hits	130	Target Neighborhood Hits	96	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX28_MOUSE
θ value	2.43343e-21 (rank : 53)	NC score	0.927897 (rank : 24)
Query Neighborhood Hits	130	Target Neighborhood Hits	112	Shared Neighborhood Hits	89
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

IF4A1_HUMAN
θ value	2.43343e-21 (rank : 54)	NC score	0.913487 (rank : 39)
Query Neighborhood Hits	130	Target Neighborhood Hits	106	Shared Neighborhood Hits	87
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
θ value	2.43343e-21 (rank : 55)	NC score	0.913487 (rank : 40)
Query Neighborhood Hits	130	Target Neighborhood Hits	106	Shared Neighborhood Hits	87
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

DDX25_MOUSE
θ value	3.17815e-21 (rank : 56)	NC score	0.900180 (rank : 60)
Query Neighborhood Hits	130	Target Neighborhood Hits	98	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DD19A_HUMAN
θ value	4.15078e-21 (rank : 57)	NC score	0.899176 (rank : 62)
Query Neighborhood Hits	130	Target Neighborhood Hits	107	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19A_MOUSE
θ value	4.15078e-21 (rank : 58)	NC score	0.898761 (rank : 63)
Query Neighborhood Hits	130	Target Neighborhood Hits	105	Shared Neighborhood Hits	83
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DDX39_MOUSE
θ value	4.15078e-21 (rank : 59)	NC score	0.913766 (rank : 38)
Query Neighborhood Hits	130	Target Neighborhood Hits	97	Shared Neighborhood Hits	85
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX25_HUMAN
θ value	9.24701e-21 (rank : 60)	NC score	0.900221 (rank : 59)
Query Neighborhood Hits	130	Target Neighborhood Hits	93	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DD19B_HUMAN
θ value	1.2077e-20 (rank : 61)	NC score	0.898208 (rank : 65)
Query Neighborhood Hits	130	Target Neighborhood Hits	109	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DDX20_MOUSE
θ value	2.5182e-18 (rank : 62)	NC score	0.896624 (rank : 66)
Query Neighborhood Hits	130	Target Neighborhood Hits	177	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX48_HUMAN
θ value	2.5182e-18 (rank : 63)	NC score	0.910712 (rank : 46)
Query Neighborhood Hits	130	Target Neighborhood Hits	102	Shared Neighborhood Hits	87
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
θ value	3.28887e-18 (rank : 64)	NC score	0.910473 (rank : 47)
Query Neighborhood Hits	130	Target Neighborhood Hits	102	Shared Neighborhood Hits	87
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX20_HUMAN
θ value	6.20254e-17 (rank : 65)	NC score	0.898404 (rank : 64)
Query Neighborhood Hits	130	Target Neighborhood Hits	121	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX5_HUMAN
θ value	6.41864e-14 (rank : 66)	NC score	0.903096 (rank : 57)
Query Neighborhood Hits	130	Target Neighborhood Hits	102	Shared Neighborhood Hits	87
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
θ value	6.41864e-14 (rank : 67)	NC score	0.902948 (rank : 58)
Query Neighborhood Hits	130	Target Neighborhood Hits	101	Shared Neighborhood Hits	87
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX53_HUMAN
θ value	2.28291e-11 (rank : 68)	NC score	0.904604 (rank : 56)
Query Neighborhood Hits	130	Target Neighborhood Hits	124	Shared Neighborhood Hits	83
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

RECQ4_HUMAN
θ value	2.44474e-05 (rank : 69)	NC score	0.535115 (rank : 69)
Query Neighborhood Hits	130	Target Neighborhood Hits	177	Shared Neighborhood Hits	89
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

FANCM_MOUSE
θ value	9.29e-05 (rank : 70)	NC score	0.452191 (rank : 72)
Query Neighborhood Hits	130	Target Neighborhood Hits	177	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

U520_HUMAN
θ value	0.00035302 (rank : 71)	NC score	0.180040 (rank : 88)
Query Neighborhood Hits	130	Target Neighborhood Hits	88	Shared Neighborhood Hits	47
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

FANCM_HUMAN
θ value	0.000602161 (rank : 72)	NC score	0.451505 (rank : 73)
Query Neighborhood Hits	130	Target Neighborhood Hits	210	Shared Neighborhood Hits	80
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

LGP2_HUMAN
θ value	0.00102713 (rank : 73)	NC score	0.350384 (rank : 83)
Query Neighborhood Hits	130	Target Neighborhood Hits	94	Shared Neighborhood Hits	75
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

DICER_MOUSE
θ value	0.00228821 (rank : 74)	NC score	0.418579 (rank : 77)
Query Neighborhood Hits	130	Target Neighborhood Hits	140	Shared Neighborhood Hits	84
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

WRN_HUMAN
θ value	0.00228821 (rank : 75)	NC score	0.449408 (rank : 74)
Query Neighborhood Hits	130	Target Neighborhood Hits	132	Shared Neighborhood Hits	80
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

WRN_MOUSE
θ value	0.00228821 (rank : 76)	NC score	0.414092 (rank : 79)
Query Neighborhood Hits	130	Target Neighborhood Hits	295	Shared Neighborhood Hits	78
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

DICER_HUMAN
θ value	0.00298849 (rank : 77)	NC score	0.418223 (rank : 78)
Query Neighborhood Hits	130	Target Neighborhood Hits	126	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

RECQ4_MOUSE
θ value	0.00390308 (rank : 78)	NC score	0.507481 (rank : 70)
Query Neighborhood Hits	130	Target Neighborhood Hits	206	Shared Neighborhood Hits	86
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

IFIH1_HUMAN
θ value	0.00509761 (rank : 79)	NC score	0.350065 (rank : 84)
Query Neighborhood Hits	130	Target Neighborhood Hits	96	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

IFIH1_MOUSE
θ value	0.0113563 (rank : 80)	NC score	0.335916 (rank : 85)
Query Neighborhood Hits	130	Target Neighborhood Hits	126	Shared Neighborhood Hits	83
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

RECQ1_MOUSE
θ value	0.0113563 (rank : 81)	NC score	0.411274 (rank : 80)
Query Neighborhood Hits	130	Target Neighborhood Hits	95	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

DDX58_MOUSE
θ value	0.0252991 (rank : 82)	NC score	0.237218 (rank : 86)
Query Neighborhood Hits	130	Target Neighborhood Hits	99	Shared Neighborhood Hits	61
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

RECQ5_HUMAN
θ value	0.0330416 (rank : 83)	NC score	0.444056 (rank : 76)
Query Neighborhood Hits	130	Target Neighborhood Hits	390	Shared Neighborhood Hits	86
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

RECQ1_HUMAN
θ value	0.0961366 (rank : 84)	NC score	0.410588 (rank : 81)
Query Neighborhood Hits	130	Target Neighborhood Hits	100	Shared Neighborhood Hits	75
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

LGP2_MOUSE
θ value	0.21417 (rank : 85)	NC score	0.352076 (rank : 82)
Query Neighborhood Hits	130	Target Neighborhood Hits	86	Shared Neighborhood Hits	72
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

LPIN3_HUMAN
θ value	0.21417 (rank : 86)	NC score	0.014561 (rank : 97)
Query Neighborhood Hits	130	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BQK8, Q5TDB9, Q9NPY8, Q9UJE5	Gene names	LPIN3, LIPN3L
Domain Architecture	No domain graphic available
Description	Lipin-3 (Lipin 3-like).

SF3B1_MOUSE
θ value	0.279714 (rank : 87)	NC score	0.025816 (rank : 93)
Query Neighborhood Hits	130	Target Neighborhood Hits	352	Shared Neighborhood Hits	14
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

CT151_HUMAN
θ value	0.62314 (rank : 88)	NC score	0.016795 (rank : 96)
Query Neighborhood Hits	130	Target Neighborhood Hits	382	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

SF3B1_HUMAN
θ value	0.62314 (rank : 89)	NC score	0.024418 (rank : 94)
Query Neighborhood Hits	130	Target Neighborhood Hits	341	Shared Neighborhood Hits	13
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

CELR3_HUMAN
θ value	0.813845 (rank : 90)	NC score	-0.002296 (rank : 128)
Query Neighborhood Hits	130	Target Neighborhood Hits	680	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

BLM_MOUSE
θ value	1.81305 (rank : 91)	NC score	0.456608 (rank : 71)
Query Neighborhood Hits	130	Target Neighborhood Hits	108	Shared Neighborhood Hits	71
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

CBX8_HUMAN
θ value	1.81305 (rank : 92)	NC score	0.009223 (rank : 107)
Query Neighborhood Hits	130	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HC52, Q96H39, Q9NR07	Gene names	CBX8, PC3, RC1
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1).

DDX58_HUMAN
θ value	1.81305 (rank : 93)	NC score	0.197067 (rank : 87)
Query Neighborhood Hits	130	Target Neighborhood Hits	105	Shared Neighborhood Hits	58
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

MLL4_HUMAN
θ value	1.81305 (rank : 94)	NC score	0.004808 (rank : 119)
Query Neighborhood Hits	130	Target Neighborhood Hits	722	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

TAU_MOUSE
θ value	2.36792 (rank : 95)	NC score	0.008915 (rank : 109)
Query Neighborhood Hits	130	Target Neighborhood Hits	502	Shared Neighborhood Hits	14
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

GRPR_HUMAN
θ value	3.0926 (rank : 96)	NC score	-0.003801 (rank : 131)
Query Neighborhood Hits	130	Target Neighborhood Hits	778	Shared Neighborhood Hits	3
SwissProt Accessions	P30550	Gene names	GRPR
Domain Architecture
Description	Gastrin-releasing peptide receptor (GRP-R) (GRP-preferring bombesin receptor).

GRPR_MOUSE
θ value	3.0926 (rank : 97)	NC score	-0.003782 (rank : 130)
Query Neighborhood Hits	130	Target Neighborhood Hits	781	Shared Neighborhood Hits	3
SwissProt Accessions	P21729	Gene names	Grpr
Domain Architecture
Description	Gastrin-releasing peptide receptor (GRP-R) (GRP-preferring bombesin receptor).

MOV10_MOUSE
θ value	3.0926 (rank : 98)	NC score	0.009129 (rank : 108)
Query Neighborhood Hits	130	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	P23249, Q9DC64	Gene names	Mov10, Gb110
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

NPAS1_MOUSE
θ value	3.0926 (rank : 99)	NC score	0.004500 (rank : 121)
Query Neighborhood Hits	130	Target Neighborhood Hits	63	Shared Neighborhood Hits	2
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

PARP4_HUMAN
θ value	3.0926 (rank : 100)	NC score	0.009946 (rank : 105)
Query Neighborhood Hits	130	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKK3, O75903, Q14682, Q9H1M6	Gene names	PARP4, ADPRTL1, KIAA0177, PARPL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 4 (EC 2.4.2.30) (PARP-4) (Vault poly(ADP- ribose) polymerase) (VPARP) (193 kDa vault protein) (PARP- related/IalphaI-related H5/proline-rich) (PH5P).

VPS72_HUMAN
θ value	3.0926 (rank : 101)	NC score	0.011571 (rank : 101)
Query Neighborhood Hits	130	Target Neighborhood Hits	274	Shared Neighborhood Hits	4
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

BLM_HUMAN
θ value	4.03905 (rank : 102)	NC score	0.444073 (rank : 75)
Query Neighborhood Hits	130	Target Neighborhood Hits	148	Shared Neighborhood Hits	76
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

CORIN_MOUSE
θ value	4.03905 (rank : 103)	NC score	-0.002999 (rank : 129)
Query Neighborhood Hits	130	Target Neighborhood Hits	451	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

FMN2_HUMAN
θ value	4.03905 (rank : 104)	NC score	0.006320 (rank : 118)
Query Neighborhood Hits	130	Target Neighborhood Hits	484	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

GSHB_MOUSE
θ value	4.03905 (rank : 105)	NC score	0.010458 (rank : 103)
Query Neighborhood Hits	130	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P51855	Gene names	Gss
Domain Architecture
Description	Glutathione synthetase (EC 6.3.2.3) (Glutathione synthase) (GSH synthetase) (GSH-S).

HELC1_HUMAN
θ value	4.03905 (rank : 106)	NC score	0.133816 (rank : 90)
Query Neighborhood Hits	130	Target Neighborhood Hits	71	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

KI67_HUMAN
θ value	4.03905 (rank : 107)	NC score	0.010837 (rank : 102)
Query Neighborhood Hits	130	Target Neighborhood Hits	581	Shared Neighborhood Hits	12
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

LYAR_MOUSE
θ value	4.03905 (rank : 108)	NC score	0.009686 (rank : 106)
Query Neighborhood Hits	130	Target Neighborhood Hits	153	Shared Neighborhood Hits	5
SwissProt Accessions	Q08288, Q9D9X2	Gene names	Lyar
Domain Architecture	No domain graphic available
Description	Cell growth-regulating nucleolar protein.

PRLR_HUMAN
θ value	4.03905 (rank : 109)	NC score	0.006775 (rank : 115)
Query Neighborhood Hits	130	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	P16471, Q16354, Q9BX87	Gene names	PRLR
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

RP1L1_HUMAN
θ value	4.03905 (rank : 110)	NC score	0.007724 (rank : 111)
Query Neighborhood Hits	130	Target Neighborhood Hits	1072	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

AMYP_HUMAN
θ value	5.27518 (rank : 111)	NC score	0.007876 (rank : 110)
Query Neighborhood Hits	130	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	P04746, Q9UBH3	Gene names	AMY2A
Domain Architecture
Description	Pancreatic alpha-amylase precursor (EC 3.2.1.1) (PA) (1,4-alpha-D- glucan glucanohydrolase).

BAT2_MOUSE
θ value	5.27518 (rank : 112)	NC score	0.006551 (rank : 116)
Query Neighborhood Hits	130	Target Neighborhood Hits	947	Shared Neighborhood Hits	19
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

DLX4_HUMAN
θ value	5.27518 (rank : 113)	NC score	-0.002138 (rank : 127)
Query Neighborhood Hits	130	Target Neighborhood Hits	350	Shared Neighborhood Hits	2
SwissProt Accessions	Q92988, O60480, Q13265, Q6PJK0, Q9HBE0	Gene names	DLX4, BP1, DLX7, DLX8
Domain Architecture	No domain graphic available
Description	Homeobox protein DLX-4 (DLX-7) (DLX-8) (Beta protein 1).

LGR4_HUMAN
θ value	5.27518 (rank : 114)	NC score	-0.001779 (rank : 126)
Query Neighborhood Hits	130	Target Neighborhood Hits	481	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BXB1, Q9NYD1	Gene names	LGR4, GPR48
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 4 precursor (G-protein coupled receptor 48).

MINT_HUMAN
θ value	5.27518 (rank : 115)	NC score	0.004553 (rank : 120)
Query Neighborhood Hits	130	Target Neighborhood Hits	1291	Shared Neighborhood Hits	23
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

RGS3_HUMAN
θ value	5.27518 (rank : 116)	NC score	0.003990 (rank : 122)
Query Neighborhood Hits	130	Target Neighborhood Hits	1375	Shared Neighborhood Hits	22
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

ATX2_HUMAN
θ value	6.88961 (rank : 117)	NC score	0.011720 (rank : 100)
Query Neighborhood Hits	130	Target Neighborhood Hits	375	Shared Neighborhood Hits	14
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

ATX2_MOUSE
θ value	6.88961 (rank : 118)	NC score	0.012798 (rank : 98)
Query Neighborhood Hits	130	Target Neighborhood Hits	445	Shared Neighborhood Hits	16
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

CHSTC_HUMAN
θ value	6.88961 (rank : 119)	NC score	0.003865 (rank : 123)
Query Neighborhood Hits	130	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NRB3, Q9NXY7	Gene names	CHST12
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 12 (EC 2.8.2.5) (Chondroitin 4-O- sulfotransferase 2) (Chondroitin 4-sulfotransferase 2) (C4ST2) (C4ST- 2) (Sulfotransferase Hlo).

GNAS1_MOUSE
θ value	6.88961 (rank : 120)	NC score	0.002213 (rank : 124)
Query Neighborhood Hits	130	Target Neighborhood Hits	651	Shared Neighborhood Hits	16
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

SPEG_HUMAN
θ value	6.88961 (rank : 121)	NC score	-0.007553 (rank : 133)
Query Neighborhood Hits	130	Target Neighborhood Hits	1762	Shared Neighborhood Hits	17
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TBX2_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.000985 (rank : 125)
Query Neighborhood Hits	130	Target Neighborhood Hits	195	Shared Neighborhood Hits	5
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

VASP_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.007213 (rank : 114)
Query Neighborhood Hits	130	Target Neighborhood Hits	201	Shared Neighborhood Hits	8
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

FMN1B_MOUSE
θ value	8.99809 (rank : 124)	NC score	0.010136 (rank : 104)
Query Neighborhood Hits	130	Target Neighborhood Hits	447	Shared Neighborhood Hits	13
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

ICAL_HUMAN
θ value	8.99809 (rank : 125)	NC score	0.012453 (rank : 99)
Query Neighborhood Hits	130	Target Neighborhood Hits	275	Shared Neighborhood Hits	10
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

MOV10_HUMAN
θ value	8.99809 (rank : 126)	NC score	0.007233 (rank : 113)
Query Neighborhood Hits	130	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCE1, Q8TEF0, Q9BSY3, Q9BUJ9	Gene names	MOV10, KIAA1631
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

NU214_HUMAN
θ value	8.99809 (rank : 127)	NC score	0.007468 (rank : 112)
Query Neighborhood Hits	130	Target Neighborhood Hits	657	Shared Neighborhood Hits	13
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

PEG3_MOUSE
θ value	8.99809 (rank : 128)	NC score	-0.006394 (rank : 132)
Query Neighborhood Hits	130	Target Neighborhood Hits	1101	Shared Neighborhood Hits	7
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

RL1D1_HUMAN
θ value	8.99809 (rank : 129)	NC score	0.018267 (rank : 95)
Query Neighborhood Hits	130	Target Neighborhood Hits	180	Shared Neighborhood Hits	10
SwissProt Accessions	O76021, Q6PL22, Q8IWS7, Q8WUZ1, Q9HDA9, Q9Y3Z9	Gene names	RSL1D1, CATX11, CSIG, PBK1
Domain Architecture	No domain graphic available
Description	Ribosomal L1 domain-containing protein 1 (Cellular senescence- inhibited gene protein) (Protein PBK1) (CATX-11).

TOIP2_HUMAN
θ value	8.99809 (rank : 130)	NC score	0.006324 (rank : 117)
Query Neighborhood Hits	130	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NFQ8	Gene names	TOR1AIP2, LULL1
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2 (Lumenal domain-like LAP1).

CC026_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.144752 (rank : 89)
Query Neighborhood Hits	130	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

CC026_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.116102 (rank : 91)
Query Neighborhood Hits	130	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

SMAL1_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.063417 (rank : 92)
Query Neighborhood Hits	130	Target Neighborhood Hits	174	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

Hits sorted by NC score

DDX51_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	130	Target Neighborhood Hits	130	Shared Neighborhood Hits	130
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX51_HUMAN
NC score	0.980622 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	130	Target Neighborhood Hits	332	Shared Neighborhood Hits	99
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX27_MOUSE
NC score	0.951820 (rank : 3)	θ value	8.02596e-49 (rank : 3)
Query Neighborhood Hits	130	Target Neighborhood Hits	174	Shared Neighborhood Hits	87
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_HUMAN
NC score	0.950033 (rank : 4)	θ value	1.51363e-47 (rank : 4)
Query Neighborhood Hits	130	Target Neighborhood Hits	197	Shared Neighborhood Hits	88
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX47_MOUSE
NC score	0.949452 (rank : 5)	θ value	1.28434e-38 (rank : 7)
Query Neighborhood Hits	130	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX49_MOUSE
NC score	0.949340 (rank : 6)	θ value	9.83387e-39 (rank : 6)
Query Neighborhood Hits	130	Target Neighborhood Hits	119	Shared Neighborhood Hits	89
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX47_HUMAN
NC score	0.948866 (rank : 7)	θ value	6.37413e-38 (rank : 8)
Query Neighborhood Hits	130	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX49_HUMAN
NC score	0.946246 (rank : 8)	θ value	3.05695e-40 (rank : 5)
Query Neighborhood Hits	130	Target Neighborhood Hits	223	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX18_MOUSE
NC score	0.940998 (rank : 9)	θ value	8.61488e-35 (rank : 11)
Query Neighborhood Hits	130	Target Neighborhood Hits	115	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX55_MOUSE
NC score	0.940812 (rank : 10)	θ value	5.22648e-32 (rank : 17)
Query Neighborhood Hits	130	Target Neighborhood Hits	111	Shared Neighborhood Hits	87
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX55_HUMAN
NC score	0.939853 (rank : 11)	θ value	5.22648e-32 (rank : 16)
Query Neighborhood Hits	130	Target Neighborhood Hits	122	Shared Neighborhood Hits	85
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX52_HUMAN
NC score	0.939372 (rank : 12)	θ value	2.77131e-33 (rank : 13)
Query Neighborhood Hits	130	Target Neighborhood Hits	107	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX52_MOUSE
NC score	0.939198 (rank : 13)	θ value	6.17384e-33 (rank : 14)
Query Neighborhood Hits	130	Target Neighborhood Hits	101	Shared Neighborhood Hits	89
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX31_HUMAN
NC score	0.938950 (rank : 14)	θ value	1.33217e-27 (rank : 31)
Query Neighborhood Hits	130	Target Neighborhood Hits	132	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX18_HUMAN
NC score	0.938643 (rank : 15)	θ value	1.12514e-34 (rank : 12)
Query Neighborhood Hits	130	Target Neighborhood Hits	124	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX10_HUMAN
NC score	0.936157 (rank : 16)	θ value	9.20422e-37 (rank : 9)
Query Neighborhood Hits	130	Target Neighborhood Hits	210	Shared Neighborhood Hits	82
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX10_MOUSE
NC score	0.935411 (rank : 17)	θ value	9.20422e-37 (rank : 10)
Query Neighborhood Hits	130	Target Neighborhood Hits	233	Shared Neighborhood Hits	82
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX56_MOUSE
NC score	0.934517 (rank : 18)	θ value	2.86786e-30 (rank : 19)
Query Neighborhood Hits	130	Target Neighborhood Hits	87	Shared Neighborhood Hits	75
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX56_HUMAN
NC score	0.934297 (rank : 19)	θ value	2.42779e-29 (rank : 25)
Query Neighborhood Hits	130	Target Neighborhood Hits	77	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DDX54_MOUSE
NC score	0.931806 (rank : 20)	θ value	1.2049e-28 (rank : 26)
Query Neighborhood Hits	130	Target Neighborhood Hits	124	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX41_HUMAN
NC score	0.930224 (rank : 21)	θ value	4.57862e-28 (rank : 28)
Query Neighborhood Hits	130	Target Neighborhood Hits	111	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
NC score	0.929889 (rank : 22)	θ value	3.50572e-28 (rank : 27)
Query Neighborhood Hits	130	Target Neighborhood Hits	115	Shared Neighborhood Hits	88
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX54_HUMAN
NC score	0.928695 (rank : 23)	θ value	1.08979e-29 (rank : 22)
Query Neighborhood Hits	130	Target Neighborhood Hits	170	Shared Neighborhood Hits	86
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX28_MOUSE
NC score	0.927897 (rank : 24)	θ value	2.43343e-21 (rank : 53)
Query Neighborhood Hits	130	Target Neighborhood Hits	112	Shared Neighborhood Hits	89
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX4_MOUSE
NC score	0.925476 (rank : 25)	θ value	5.06226e-27 (rank : 33)
Query Neighborhood Hits	130	Target Neighborhood Hits	100	Shared Neighborhood Hits	89
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX6_HUMAN
NC score	0.924940 (rank : 26)	θ value	5.79196e-23 (rank : 43)
Query Neighborhood Hits	130	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX4_HUMAN
NC score	0.924852 (rank : 27)	θ value	5.97985e-28 (rank : 29)
Query Neighborhood Hits	130	Target Neighborhood Hits	123	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX6_MOUSE
NC score	0.924834 (rank : 28)	θ value	2.59989e-23 (rank : 38)
Query Neighborhood Hits	130	Target Neighborhood Hits	98	Shared Neighborhood Hits	87
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX50_HUMAN
NC score	0.924335 (rank : 29)	θ value	2.42779e-29 (rank : 24)
Query Neighborhood Hits	130	Target Neighborhood Hits	132	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_MOUSE
NC score	0.924309 (rank : 30)	θ value	1.4233e-29 (rank : 23)
Query Neighborhood Hits	130	Target Neighborhood Hits	137	Shared Neighborhood Hits	87
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX28_HUMAN
NC score	0.923620 (rank : 31)	θ value	2.87452e-22 (rank : 47)
Query Neighborhood Hits	130	Target Neighborhood Hits	103	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX43_HUMAN
NC score	0.923099 (rank : 32)	θ value	5.06226e-27 (rank : 32)
Query Neighborhood Hits	130	Target Neighborhood Hits	120	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX17_MOUSE
NC score	0.917395 (rank : 33)	θ value	9.54697e-26 (rank : 35)
Query Neighborhood Hits	130	Target Neighborhood Hits	105	Shared Neighborhood Hits	87
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX17_HUMAN
NC score	0.917237 (rank : 34)	θ value	9.54697e-26 (rank : 34)
Query Neighborhood Hits	130	Target Neighborhood Hits	104	Shared Neighborhood Hits	87
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX24_MOUSE
NC score	0.916260 (rank : 35)	θ value	1.6852e-22 (rank : 44)
Query Neighborhood Hits	130	Target Neighborhood Hits	147	Shared Neighborhood Hits	87
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX39_HUMAN
NC score	0.915819 (rank : 36)	θ value	4.43474e-23 (rank : 40)
Query Neighborhood Hits	130	Target Neighborhood Hits	94	Shared Neighborhood Hits	86
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX24_HUMAN
NC score	0.914404 (rank : 37)	θ value	4.43474e-23 (rank : 39)
Query Neighborhood Hits	130	Target Neighborhood Hits	190	Shared Neighborhood Hits	87
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX39_MOUSE
NC score	0.913766 (rank : 38)	θ value	4.15078e-21 (rank : 59)
Query Neighborhood Hits	130	Target Neighborhood Hits	97	Shared Neighborhood Hits	85
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

IF4A1_HUMAN
NC score	0.913487 (rank : 39)	θ value	2.43343e-21 (rank : 54)
Query Neighborhood Hits	130	Target Neighborhood Hits	106	Shared Neighborhood Hits	87
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
NC score	0.913487 (rank : 40)	θ value	2.43343e-21 (rank : 55)
Query Neighborhood Hits	130	Target Neighborhood Hits	106	Shared Neighborhood Hits	87
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

UAP56_HUMAN
NC score	0.913147 (rank : 41)	θ value	1.09232e-21 (rank : 51)
Query Neighborhood Hits	130	Target Neighborhood Hits	96	Shared Neighborhood Hits	85
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
NC score	0.913117 (rank : 42)	θ value	1.09232e-21 (rank : 52)
Query Neighborhood Hits	130	Target Neighborhood Hits	96	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

IF4A2_HUMAN
NC score	0.913113 (rank : 43)	θ value	1.09232e-21 (rank : 49)
Query Neighborhood Hits	130	Target Neighborhood Hits	102	Shared Neighborhood Hits	87
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
NC score	0.913113 (rank : 44)	θ value	1.09232e-21 (rank : 50)
Query Neighborhood Hits	130	Target Neighborhood Hits	102	Shared Neighborhood Hits	87
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX21_HUMAN
NC score	0.912854 (rank : 45)	θ value	2.86786e-30 (rank : 18)
Query Neighborhood Hits	130	Target Neighborhood Hits	308	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX48_HUMAN
NC score	0.910712 (rank : 46)	θ value	2.5182e-18 (rank : 63)
Query Neighborhood Hits	130	Target Neighborhood Hits	102	Shared Neighborhood Hits	87
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
NC score	0.910473 (rank : 47)	θ value	3.28887e-18 (rank : 64)
Query Neighborhood Hits	130	Target Neighborhood Hits	102	Shared Neighborhood Hits	87
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX46_HUMAN
NC score	0.908991 (rank : 48)	θ value	3.74554e-30 (rank : 20)
Query Neighborhood Hits	130	Target Neighborhood Hits	357	Shared Neighborhood Hits	92
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX3X_HUMAN
NC score	0.908363 (rank : 49)	θ value	8.93572e-24 (rank : 36)
Query Neighborhood Hits	130	Target Neighborhood Hits	122	Shared Neighborhood Hits	90
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX3Y_MOUSE
NC score	0.908360 (rank : 50)	θ value	2.20094e-22 (rank : 45)
Query Neighborhood Hits	130	Target Neighborhood Hits	126	Shared Neighborhood Hits	88
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

PL10_MOUSE
NC score	0.908293 (rank : 51)	θ value	1.99067e-23 (rank : 37)
Query Neighborhood Hits	130	Target Neighborhood Hits	120	Shared Neighborhood Hits	88
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3X_MOUSE
NC score	0.907278 (rank : 52)	θ value	5.79196e-23 (rank : 41)
Query Neighborhood Hits	130	Target Neighborhood Hits	117	Shared Neighborhood Hits	90
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX46_MOUSE
NC score	0.906806 (rank : 53)	θ value	3.74554e-30 (rank : 21)
Query Neighborhood Hits	130	Target Neighborhood Hits	358	Shared Neighborhood Hits	92
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX21_MOUSE
NC score	0.906626 (rank : 54)	θ value	5.22648e-32 (rank : 15)
Query Neighborhood Hits	130	Target Neighborhood Hits	350	Shared Neighborhood Hits	94
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX3Y_HUMAN
NC score	0.905536 (rank : 55)	θ value	5.79196e-23 (rank : 42)
Query Neighborhood Hits	130	Target Neighborhood Hits	121	Shared Neighborhood Hits	89
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX53_HUMAN
NC score	0.904604 (rank : 56)	θ value	2.28291e-11 (rank : 68)
Query Neighborhood Hits	130	Target Neighborhood Hits	124	Shared Neighborhood Hits	83
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX5_HUMAN
NC score	0.903096 (rank : 57)	θ value	6.41864e-14 (rank : 66)
Query Neighborhood Hits	130	Target Neighborhood Hits	102	Shared Neighborhood Hits	87
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
NC score	0.902948 (rank : 58)	θ value	6.41864e-14 (rank : 67)
Query Neighborhood Hits	130	Target Neighborhood Hits	101	Shared Neighborhood Hits	87
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX25_HUMAN
NC score	0.900221 (rank : 59)	θ value	9.24701e-21 (rank : 60)
Query Neighborhood Hits	130	Target Neighborhood Hits	93	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX25_MOUSE
NC score	0.900180 (rank : 60)	θ value	3.17815e-21 (rank : 56)
Query Neighborhood Hits	130	Target Neighborhood Hits	98	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX23_HUMAN
NC score	0.900130 (rank : 61)	θ value	1.02001e-27 (rank : 30)
Query Neighborhood Hits	130	Target Neighborhood Hits	486	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DD19A_HUMAN
NC score	0.899176 (rank : 62)	θ value	4.15078e-21 (rank : 57)
Query Neighborhood Hits	130	Target Neighborhood Hits	107	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19A_MOUSE
NC score	0.898761 (rank : 63)	θ value	4.15078e-21 (rank : 58)
Query Neighborhood Hits	130	Target Neighborhood Hits	105	Shared Neighborhood Hits	83
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DDX20_HUMAN
NC score	0.898404 (rank : 64)	θ value	6.20254e-17 (rank : 65)
Query Neighborhood Hits	130	Target Neighborhood Hits	121	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DD19B_HUMAN
NC score	0.898208 (rank : 65)	θ value	1.2077e-20 (rank : 61)
Query Neighborhood Hits	130	Target Neighborhood Hits	109	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DDX20_MOUSE
NC score	0.896624 (rank : 66)	θ value	2.5182e-18 (rank : 62)
Query Neighborhood Hits	130	Target Neighborhood Hits	177	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX1_MOUSE
NC score	0.867415 (rank : 67)	θ value	2.87452e-22 (rank : 46)
Query Neighborhood Hits	130	Target Neighborhood Hits	112	Shared Neighborhood Hits	83
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX1_HUMAN
NC score	0.866039 (rank : 68)	θ value	3.75424e-22 (rank : 48)
Query Neighborhood Hits	130	Target Neighborhood Hits	110	Shared Neighborhood Hits	83
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

RECQ4_HUMAN
NC score	0.535115 (rank : 69)	θ value	2.44474e-05 (rank : 69)
Query Neighborhood Hits	130	Target Neighborhood Hits	177	Shared Neighborhood Hits	89
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RECQ4_MOUSE
NC score	0.507481 (rank : 70)	θ value	0.00390308 (rank : 78)
Query Neighborhood Hits	130	Target Neighborhood Hits	206	Shared Neighborhood Hits	86
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

BLM_MOUSE
NC score	0.456608 (rank : 71)	θ value	1.81305 (rank : 91)
Query Neighborhood Hits	130	Target Neighborhood Hits	108	Shared Neighborhood Hits	71
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

FANCM_MOUSE
NC score	0.452191 (rank : 72)	θ value	9.29e-05 (rank : 70)
Query Neighborhood Hits	130	Target Neighborhood Hits	177	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

FANCM_HUMAN
NC score	0.451505 (rank : 73)	θ value	0.000602161 (rank : 72)
Query Neighborhood Hits	130	Target Neighborhood Hits	210	Shared Neighborhood Hits	80
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

WRN_HUMAN
NC score	0.449408 (rank : 74)	θ value	0.00228821 (rank : 75)
Query Neighborhood Hits	130	Target Neighborhood Hits	132	Shared Neighborhood Hits	80
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

BLM_HUMAN
NC score	0.444073 (rank : 75)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	130	Target Neighborhood Hits	148	Shared Neighborhood Hits	76
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

RECQ5_HUMAN
NC score	0.444056 (rank : 76)	θ value	0.0330416 (rank : 83)
Query Neighborhood Hits	130	Target Neighborhood Hits	390	Shared Neighborhood Hits	86
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

DICER_MOUSE
NC score	0.418579 (rank : 77)	θ value	0.00228821 (rank : 74)
Query Neighborhood Hits	130	Target Neighborhood Hits	140	Shared Neighborhood Hits	84
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

DICER_HUMAN
NC score	0.418223 (rank : 78)	θ value	0.00298849 (rank : 77)
Query Neighborhood Hits	130	Target Neighborhood Hits	126	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

WRN_MOUSE
NC score	0.414092 (rank : 79)	θ value	0.00228821 (rank : 76)
Query Neighborhood Hits	130	Target Neighborhood Hits	295	Shared Neighborhood Hits	78
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

RECQ1_MOUSE
NC score	0.411274 (rank : 80)	θ value	0.0113563 (rank : 81)
Query Neighborhood Hits	130	Target Neighborhood Hits	95	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ1_HUMAN
NC score	0.410588 (rank : 81)	θ value	0.0961366 (rank : 84)
Query Neighborhood Hits	130	Target Neighborhood Hits	100	Shared Neighborhood Hits	75
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

LGP2_MOUSE
NC score	0.352076 (rank : 82)	θ value	0.21417 (rank : 85)
Query Neighborhood Hits	130	Target Neighborhood Hits	86	Shared Neighborhood Hits	72
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

LGP2_HUMAN
NC score	0.350384 (rank : 83)	θ value	0.00102713 (rank : 73)
Query Neighborhood Hits	130	Target Neighborhood Hits	94	Shared Neighborhood Hits	75
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

IFIH1_HUMAN
NC score	0.350065 (rank : 84)	θ value	0.00509761 (rank : 79)
Query Neighborhood Hits	130	Target Neighborhood Hits	96	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

IFIH1_MOUSE
NC score	0.335916 (rank : 85)	θ value	0.0113563 (rank : 80)
Query Neighborhood Hits	130	Target Neighborhood Hits	126	Shared Neighborhood Hits	83
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

DDX58_MOUSE
NC score	0.237218 (rank : 86)	θ value	0.0252991 (rank : 82)
Query Neighborhood Hits	130	Target Neighborhood Hits	99	Shared Neighborhood Hits	61
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DDX58_HUMAN
NC score	0.197067 (rank : 87)	θ value	1.81305 (rank : 93)
Query Neighborhood Hits	130	Target Neighborhood Hits	105	Shared Neighborhood Hits	58
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

U520_HUMAN
NC score	0.180040 (rank : 88)	θ value	0.00035302 (rank : 71)
Query Neighborhood Hits	130	Target Neighborhood Hits	88	Shared Neighborhood Hits	47
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

CC026_HUMAN
NC score	0.144752 (rank : 89)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	130	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

HELC1_HUMAN
NC score	0.133816 (rank : 90)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	130	Target Neighborhood Hits	71	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

CC026_MOUSE
NC score	0.116102 (rank : 91)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	130	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

SMAL1_HUMAN
NC score	0.063417 (rank : 92)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	130	Target Neighborhood Hits	174	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

SF3B1_MOUSE
NC score	0.025816 (rank : 93)	θ value	0.279714 (rank : 87)
Query Neighborhood Hits	130	Target Neighborhood Hits	352	Shared Neighborhood Hits	14
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_HUMAN
NC score	0.024418 (rank : 94)	θ value	0.62314 (rank : 89)
Query Neighborhood Hits	130	Target Neighborhood Hits	341	Shared Neighborhood Hits	13
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

RL1D1_HUMAN
NC score	0.018267 (rank : 95)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	130	Target Neighborhood Hits	180	Shared Neighborhood Hits	10
SwissProt Accessions	O76021, Q6PL22, Q8IWS7, Q8WUZ1, Q9HDA9, Q9Y3Z9	Gene names	RSL1D1, CATX11, CSIG, PBK1
Domain Architecture	No domain graphic available
Description	Ribosomal L1 domain-containing protein 1 (Cellular senescence- inhibited gene protein) (Protein PBK1) (CATX-11).

CT151_HUMAN
NC score	0.016795 (rank : 96)	θ value	0.62314 (rank : 88)
Query Neighborhood Hits	130	Target Neighborhood Hits	382	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

LPIN3_HUMAN
NC score	0.014561 (rank : 97)	θ value	0.21417 (rank : 86)
Query Neighborhood Hits	130	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BQK8, Q5TDB9, Q9NPY8, Q9UJE5	Gene names	LPIN3, LIPN3L
Domain Architecture	No domain graphic available
Description	Lipin-3 (Lipin 3-like).

ATX2_MOUSE
NC score	0.012798 (rank : 98)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	130	Target Neighborhood Hits	445	Shared Neighborhood Hits	16
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

ICAL_HUMAN
NC score	0.012453 (rank : 99)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	130	Target Neighborhood Hits	275	Shared Neighborhood Hits	10
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

ATX2_HUMAN
NC score	0.011720 (rank : 100)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	130	Target Neighborhood Hits	375	Shared Neighborhood Hits	14
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

VPS72_HUMAN
NC score	0.011571 (rank : 101)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	130	Target Neighborhood Hits	274	Shared Neighborhood Hits	4
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

KI67_HUMAN
NC score	0.010837 (rank : 102)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	130	Target Neighborhood Hits	581	Shared Neighborhood Hits	12
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

GSHB_MOUSE
NC score	0.010458 (rank : 103)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	130	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P51855	Gene names	Gss
Domain Architecture
Description	Glutathione synthetase (EC 6.3.2.3) (Glutathione synthase) (GSH synthetase) (GSH-S).

FMN1B_MOUSE
NC score	0.010136 (rank : 104)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	130	Target Neighborhood Hits	447	Shared Neighborhood Hits	13
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

PARP4_HUMAN
NC score	0.009946 (rank : 105)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	130	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKK3, O75903, Q14682, Q9H1M6	Gene names	PARP4, ADPRTL1, KIAA0177, PARPL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 4 (EC 2.4.2.30) (PARP-4) (Vault poly(ADP- ribose) polymerase) (VPARP) (193 kDa vault protein) (PARP- related/IalphaI-related H5/proline-rich) (PH5P).

LYAR_MOUSE
NC score	0.009686 (rank : 106)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	130	Target Neighborhood Hits	153	Shared Neighborhood Hits	5
SwissProt Accessions	Q08288, Q9D9X2	Gene names	Lyar
Domain Architecture	No domain graphic available
Description	Cell growth-regulating nucleolar protein.

CBX8_HUMAN
NC score	0.009223 (rank : 107)	θ value	1.81305 (rank : 92)
Query Neighborhood Hits	130	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HC52, Q96H39, Q9NR07	Gene names	CBX8, PC3, RC1
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1).

MOV10_MOUSE
NC score	0.009129 (rank : 108)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	130	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	P23249, Q9DC64	Gene names	Mov10, Gb110
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

TAU_MOUSE
NC score	0.008915 (rank : 109)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	130	Target Neighborhood Hits	502	Shared Neighborhood Hits	14
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

AMYP_HUMAN
NC score	0.007876 (rank : 110)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	130	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	P04746, Q9UBH3	Gene names	AMY2A
Domain Architecture
Description	Pancreatic alpha-amylase precursor (EC 3.2.1.1) (PA) (1,4-alpha-D- glucan glucanohydrolase).

RP1L1_HUMAN
NC score	0.007724 (rank : 111)	θ value	4.03905 (rank : 110)
Query Neighborhood Hits	130	Target Neighborhood Hits	1072	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

NU214_HUMAN
NC score	0.007468 (rank : 112)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	130	Target Neighborhood Hits	657	Shared Neighborhood Hits	13
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

MOV10_HUMAN
NC score	0.007233 (rank : 113)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	130	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCE1, Q8TEF0, Q9BSY3, Q9BUJ9	Gene names	MOV10, KIAA1631
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

VASP_HUMAN
NC score	0.007213 (rank : 114)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	130	Target Neighborhood Hits	201	Shared Neighborhood Hits	8
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

PRLR_HUMAN
NC score	0.006775 (rank : 115)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	130	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	P16471, Q16354, Q9BX87	Gene names	PRLR
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

BAT2_MOUSE
NC score	0.006551 (rank : 116)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	130	Target Neighborhood Hits	947	Shared Neighborhood Hits	19
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

TOIP2_HUMAN
NC score	0.006324 (rank : 117)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	130	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NFQ8	Gene names	TOR1AIP2, LULL1
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2 (Lumenal domain-like LAP1).

FMN2_HUMAN
NC score	0.006320 (rank : 118)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	130	Target Neighborhood Hits	484	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

MLL4_HUMAN
NC score	0.004808 (rank : 119)	θ value	1.81305 (rank : 94)
Query Neighborhood Hits	130	Target Neighborhood Hits	722	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MINT_HUMAN
NC score	0.004553 (rank : 120)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	130	Target Neighborhood Hits	1291	Shared Neighborhood Hits	23
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NPAS1_MOUSE
NC score	0.004500 (rank : 121)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	130	Target Neighborhood Hits	63	Shared Neighborhood Hits	2
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

RGS3_HUMAN
NC score	0.003990 (rank : 122)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	130	Target Neighborhood Hits	1375	Shared Neighborhood Hits	22
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

CHSTC_HUMAN
NC score	0.003865 (rank : 123)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	130	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NRB3, Q9NXY7	Gene names	CHST12
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 12 (EC 2.8.2.5) (Chondroitin 4-O- sulfotransferase 2) (Chondroitin 4-sulfotransferase 2) (C4ST2) (C4ST- 2) (Sulfotransferase Hlo).

GNAS1_MOUSE
NC score	0.002213 (rank : 124)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	130	Target Neighborhood Hits	651	Shared Neighborhood Hits	16
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

TBX2_HUMAN
NC score	0.000985 (rank : 125)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	130	Target Neighborhood Hits	195	Shared Neighborhood Hits	5
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

LGR4_HUMAN
NC score	-0.001779 (rank : 126)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	130	Target Neighborhood Hits	481	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BXB1, Q9NYD1	Gene names	LGR4, GPR48
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 4 precursor (G-protein coupled receptor 48).

DLX4_HUMAN
NC score	-0.002138 (rank : 127)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	130	Target Neighborhood Hits	350	Shared Neighborhood Hits	2
SwissProt Accessions	Q92988, O60480, Q13265, Q6PJK0, Q9HBE0	Gene names	DLX4, BP1, DLX7, DLX8
Domain Architecture	No domain graphic available
Description	Homeobox protein DLX-4 (DLX-7) (DLX-8) (Beta protein 1).

CELR3_HUMAN
NC score	-0.002296 (rank : 128)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	130	Target Neighborhood Hits	680	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CORIN_MOUSE
NC score	-0.002999 (rank : 129)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	130	Target Neighborhood Hits	451	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

GRPR_MOUSE
NC score	-0.003782 (rank : 130)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	130	Target Neighborhood Hits	781	Shared Neighborhood Hits	3
SwissProt Accessions	P21729	Gene names	Grpr
Domain Architecture
Description	Gastrin-releasing peptide receptor (GRP-R) (GRP-preferring bombesin receptor).

GRPR_HUMAN
NC score	-0.003801 (rank : 131)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	130	Target Neighborhood Hits	778	Shared Neighborhood Hits	3
SwissProt Accessions	P30550	Gene names	GRPR
Domain Architecture
Description	Gastrin-releasing peptide receptor (GRP-R) (GRP-preferring bombesin receptor).

PEG3_MOUSE
NC score	-0.006394 (rank : 132)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	130	Target Neighborhood Hits	1101	Shared Neighborhood Hits	7
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

SPEG_HUMAN
NC score	-0.007553 (rank : 133)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	130	Target Neighborhood Hits	1762	Shared Neighborhood Hits	17
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).