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Network neighborhood for query Sequence : WRN_HUMAN

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WRN_HUMAN
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

WRN_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	132	Target Neighborhood Hits	132	Shared Neighborhood Hits	132
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

WRN_MOUSE
θ value	0 (rank : 2)	NC score	0.960445 (rank : 2)
Query Neighborhood Hits	132	Target Neighborhood Hits	295	Shared Neighborhood Hits	91
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

RECQ1_HUMAN
θ value	9.43692e-66 (rank : 3)	NC score	0.873212 (rank : 4)
Query Neighborhood Hits	132	Target Neighborhood Hits	100	Shared Neighborhood Hits	74
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ1_MOUSE
θ value	2.10232e-65 (rank : 4)	NC score	0.876514 (rank : 3)
Query Neighborhood Hits	132	Target Neighborhood Hits	95	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

BLM_MOUSE
θ value	3.84025e-59 (rank : 5)	NC score	0.853674 (rank : 5)
Query Neighborhood Hits	132	Target Neighborhood Hits	108	Shared Neighborhood Hits	71
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

BLM_HUMAN
θ value	1.61343e-57 (rank : 6)	NC score	0.846533 (rank : 6)
Query Neighborhood Hits	132	Target Neighborhood Hits	148	Shared Neighborhood Hits	76
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

RECQ5_HUMAN
θ value	1.51013e-55 (rank : 7)	NC score	0.820234 (rank : 7)
Query Neighborhood Hits	132	Target Neighborhood Hits	390	Shared Neighborhood Hits	73
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

RECQ4_HUMAN
θ value	3.61106e-41 (rank : 8)	NC score	0.808735 (rank : 8)
Query Neighborhood Hits	132	Target Neighborhood Hits	177	Shared Neighborhood Hits	83
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RECQ4_MOUSE
θ value	5.21438e-40 (rank : 9)	NC score	0.799419 (rank : 9)
Query Neighborhood Hits	132	Target Neighborhood Hits	206	Shared Neighborhood Hits	83
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

DDX46_HUMAN
θ value	1.63604e-09 (rank : 10)	NC score	0.518026 (rank : 13)
Query Neighborhood Hits	132	Target Neighborhood Hits	357	Shared Neighborhood Hits	92
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
θ value	1.63604e-09 (rank : 11)	NC score	0.517809 (rank : 14)
Query Neighborhood Hits	132	Target Neighborhood Hits	358	Shared Neighborhood Hits	92
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX3Y_MOUSE
θ value	2.13673e-09 (rank : 12)	NC score	0.498683 (rank : 27)
Query Neighborhood Hits	132	Target Neighborhood Hits	126	Shared Neighborhood Hits	79
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX3X_MOUSE
θ value	3.64472e-09 (rank : 13)	NC score	0.503051 (rank : 22)
Query Neighborhood Hits	132	Target Neighborhood Hits	117	Shared Neighborhood Hits	78
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

EXDL2_HUMAN
θ value	3.64472e-09 (rank : 14)	NC score	0.254095 (rank : 78)
Query Neighborhood Hits	132	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NVH0, Q8N3D3	Gene names	EXDL2, C14orf114
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.

EXDL2_MOUSE
θ value	3.64472e-09 (rank : 15)	NC score	0.250269 (rank : 79)
Query Neighborhood Hits	132	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VEG4	Gene names	Exdl2
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.

DDX3X_HUMAN
θ value	8.11959e-09 (rank : 16)	NC score	0.501528 (rank : 24)
Query Neighborhood Hits	132	Target Neighborhood Hits	122	Shared Neighborhood Hits	79
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX17_HUMAN
θ value	1.06045e-08 (rank : 17)	NC score	0.522558 (rank : 11)
Query Neighborhood Hits	132	Target Neighborhood Hits	104	Shared Neighborhood Hits	78
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX17_MOUSE
θ value	1.06045e-08 (rank : 18)	NC score	0.522630 (rank : 10)
Query Neighborhood Hits	132	Target Neighborhood Hits	105	Shared Neighborhood Hits	78
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

PL10_MOUSE
θ value	4.0297e-08 (rank : 19)	NC score	0.499734 (rank : 26)
Query Neighborhood Hits	132	Target Neighborhood Hits	120	Shared Neighborhood Hits	78
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3Y_HUMAN
θ value	8.97725e-08 (rank : 20)	NC score	0.500361 (rank : 25)
Query Neighborhood Hits	132	Target Neighborhood Hits	121	Shared Neighborhood Hits	78
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX52_MOUSE
θ value	1.17247e-07 (rank : 21)	NC score	0.504129 (rank : 17)
Query Neighborhood Hits	132	Target Neighborhood Hits	101	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX48_HUMAN
θ value	1.99992e-07 (rank : 22)	NC score	0.494201 (rank : 30)
Query Neighborhood Hits	132	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
θ value	1.99992e-07 (rank : 23)	NC score	0.493998 (rank : 31)
Query Neighborhood Hits	132	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX5_HUMAN
θ value	2.61198e-07 (rank : 24)	NC score	0.517767 (rank : 15)
Query Neighborhood Hits	132	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
θ value	2.61198e-07 (rank : 25)	NC score	0.518247 (rank : 12)
Query Neighborhood Hits	132	Target Neighborhood Hits	101	Shared Neighborhood Hits	78
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX43_HUMAN
θ value	1.29631e-06 (rank : 26)	NC score	0.506150 (rank : 16)
Query Neighborhood Hits	132	Target Neighborhood Hits	120	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX52_HUMAN
θ value	1.69304e-06 (rank : 27)	NC score	0.503053 (rank : 21)
Query Neighborhood Hits	132	Target Neighborhood Hits	107	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX6_HUMAN
θ value	2.21117e-06 (rank : 28)	NC score	0.503859 (rank : 19)
Query Neighborhood Hits	132	Target Neighborhood Hits	97	Shared Neighborhood Hits	82
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
θ value	2.21117e-06 (rank : 29)	NC score	0.503758 (rank : 20)
Query Neighborhood Hits	132	Target Neighborhood Hits	98	Shared Neighborhood Hits	82
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX54_MOUSE
θ value	2.88788e-06 (rank : 30)	NC score	0.474014 (rank : 43)
Query Neighborhood Hits	132	Target Neighborhood Hits	124	Shared Neighborhood Hits	82
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

IF4A1_HUMAN
θ value	4.92598e-06 (rank : 31)	NC score	0.479053 (rank : 38)
Query Neighborhood Hits	132	Target Neighborhood Hits	106	Shared Neighborhood Hits	78
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
θ value	4.92598e-06 (rank : 32)	NC score	0.479053 (rank : 39)
Query Neighborhood Hits	132	Target Neighborhood Hits	106	Shared Neighborhood Hits	78
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

DDX23_HUMAN
θ value	6.43352e-06 (rank : 33)	NC score	0.491591 (rank : 32)
Query Neighborhood Hits	132	Target Neighborhood Hits	486	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX54_HUMAN
θ value	6.43352e-06 (rank : 34)	NC score	0.470921 (rank : 47)
Query Neighborhood Hits	132	Target Neighborhood Hits	170	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX24_HUMAN
θ value	8.40245e-06 (rank : 35)	NC score	0.468722 (rank : 50)
Query Neighborhood Hits	132	Target Neighborhood Hits	190	Shared Neighborhood Hits	83
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

IF4A2_HUMAN
θ value	1.09739e-05 (rank : 36)	NC score	0.479660 (rank : 36)
Query Neighborhood Hits	132	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
θ value	1.09739e-05 (rank : 37)	NC score	0.479660 (rank : 37)
Query Neighborhood Hits	132	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX41_HUMAN
θ value	1.43324e-05 (rank : 38)	NC score	0.503986 (rank : 18)
Query Neighborhood Hits	132	Target Neighborhood Hits	111	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
θ value	1.43324e-05 (rank : 39)	NC score	0.502209 (rank : 23)
Query Neighborhood Hits	132	Target Neighborhood Hits	115	Shared Neighborhood Hits	79
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX50_HUMAN
θ value	1.43324e-05 (rank : 40)	NC score	0.498627 (rank : 28)
Query Neighborhood Hits	132	Target Neighborhood Hits	132	Shared Neighborhood Hits	81
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_MOUSE
θ value	1.43324e-05 (rank : 41)	NC score	0.498458 (rank : 29)
Query Neighborhood Hits	132	Target Neighborhood Hits	137	Shared Neighborhood Hits	81
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX24_MOUSE
θ value	2.44474e-05 (rank : 42)	NC score	0.470188 (rank : 49)
Query Neighborhood Hits	132	Target Neighborhood Hits	147	Shared Neighborhood Hits	81
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX49_HUMAN
θ value	4.1701e-05 (rank : 43)	NC score	0.484959 (rank : 35)
Query Neighborhood Hits	132	Target Neighborhood Hits	223	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX49_MOUSE
θ value	4.1701e-05 (rank : 44)	NC score	0.488640 (rank : 33)
Query Neighborhood Hits	132	Target Neighborhood Hits	119	Shared Neighborhood Hits	81
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX21_HUMAN
θ value	0.000158464 (rank : 45)	NC score	0.488400 (rank : 34)
Query Neighborhood Hits	132	Target Neighborhood Hits	308	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX27_MOUSE
θ value	0.000270298 (rank : 46)	NC score	0.477661 (rank : 41)
Query Neighborhood Hits	132	Target Neighborhood Hits	174	Shared Neighborhood Hits	84
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_HUMAN
θ value	0.000461057 (rank : 47)	NC score	0.474744 (rank : 42)
Query Neighborhood Hits	132	Target Neighborhood Hits	197	Shared Neighborhood Hits	83
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX39_HUMAN
θ value	0.000786445 (rank : 48)	NC score	0.470393 (rank : 48)
Query Neighborhood Hits	132	Target Neighborhood Hits	94	Shared Neighborhood Hits	78
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX21_MOUSE
θ value	0.00102713 (rank : 49)	NC score	0.478780 (rank : 40)
Query Neighborhood Hits	132	Target Neighborhood Hits	350	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX39_MOUSE
θ value	0.00102713 (rank : 50)	NC score	0.468102 (rank : 52)
Query Neighborhood Hits	132	Target Neighborhood Hits	97	Shared Neighborhood Hits	78
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX47_HUMAN
θ value	0.00102713 (rank : 51)	NC score	0.472446 (rank : 45)
Query Neighborhood Hits	132	Target Neighborhood Hits	97	Shared Neighborhood Hits	78
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_MOUSE
θ value	0.00102713 (rank : 52)	NC score	0.472215 (rank : 46)
Query Neighborhood Hits	132	Target Neighborhood Hits	97	Shared Neighborhood Hits	78
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX18_HUMAN
θ value	0.00175202 (rank : 53)	NC score	0.430809 (rank : 66)
Query Neighborhood Hits	132	Target Neighborhood Hits	124	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX51_MOUSE
θ value	0.00228821 (rank : 54)	NC score	0.449408 (rank : 58)
Query Neighborhood Hits	132	Target Neighborhood Hits	130	Shared Neighborhood Hits	80
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX51_HUMAN
θ value	0.00509761 (rank : 55)	NC score	0.446955 (rank : 59)
Query Neighborhood Hits	132	Target Neighborhood Hits	332	Shared Neighborhood Hits	81
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX10_HUMAN
θ value	0.00665767 (rank : 56)	NC score	0.449890 (rank : 57)
Query Neighborhood Hits	132	Target Neighborhood Hits	210	Shared Neighborhood Hits	87
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX31_HUMAN
θ value	0.00665767 (rank : 57)	NC score	0.457015 (rank : 56)
Query Neighborhood Hits	132	Target Neighborhood Hits	132	Shared Neighborhood Hits	80
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

HELC1_HUMAN
θ value	0.00869519 (rank : 58)	NC score	0.178648 (rank : 85)
Query Neighborhood Hits	132	Target Neighborhood Hits	71	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

UAP56_HUMAN
θ value	0.00869519 (rank : 59)	NC score	0.460563 (rank : 54)
Query Neighborhood Hits	132	Target Neighborhood Hits	96	Shared Neighborhood Hits	78
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
θ value	0.00869519 (rank : 60)	NC score	0.460418 (rank : 55)
Query Neighborhood Hits	132	Target Neighborhood Hits	96	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX25_MOUSE
θ value	0.0113563 (rank : 61)	NC score	0.423939 (rank : 72)
Query Neighborhood Hits	132	Target Neighborhood Hits	98	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DD19A_HUMAN
θ value	0.0148317 (rank : 62)	NC score	0.430260 (rank : 67)
Query Neighborhood Hits	132	Target Neighborhood Hits	107	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19A_MOUSE
θ value	0.0148317 (rank : 63)	NC score	0.429198 (rank : 69)
Query Neighborhood Hits	132	Target Neighborhood Hits	105	Shared Neighborhood Hits	76
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DD19B_HUMAN
θ value	0.0148317 (rank : 64)	NC score	0.430021 (rank : 68)
Query Neighborhood Hits	132	Target Neighborhood Hits	109	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

U520_HUMAN
θ value	0.0148317 (rank : 65)	NC score	0.198409 (rank : 84)
Query Neighborhood Hits	132	Target Neighborhood Hits	88	Shared Neighborhood Hits	45
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

DDX10_MOUSE
θ value	0.0193708 (rank : 66)	NC score	0.446347 (rank : 60)
Query Neighborhood Hits	132	Target Neighborhood Hits	233	Shared Neighborhood Hits	88
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX25_HUMAN
θ value	0.0193708 (rank : 67)	NC score	0.426105 (rank : 70)
Query Neighborhood Hits	132	Target Neighborhood Hits	93	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX18_MOUSE
θ value	0.0736092 (rank : 68)	NC score	0.421894 (rank : 73)
Query Neighborhood Hits	132	Target Neighborhood Hits	115	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

MTO1_MOUSE
θ value	0.0736092 (rank : 69)	NC score	0.044484 (rank : 99)
Query Neighborhood Hits	132	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q923Z3, Q9D2Q5	Gene names	Mto1
Domain Architecture	No domain graphic available
Description	Protein MTO1 homolog, mitochondrial precursor.

DDX1_HUMAN
θ value	0.0961366 (rank : 70)	NC score	0.438139 (rank : 63)
Query Neighborhood Hits	132	Target Neighborhood Hits	110	Shared Neighborhood Hits	77
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX1_MOUSE
θ value	0.0961366 (rank : 71)	NC score	0.440995 (rank : 62)
Query Neighborhood Hits	132	Target Neighborhood Hits	112	Shared Neighborhood Hits	77
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX4_HUMAN
θ value	0.0961366 (rank : 72)	NC score	0.468543 (rank : 51)
Query Neighborhood Hits	132	Target Neighborhood Hits	123	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX4_MOUSE
θ value	0.0961366 (rank : 73)	NC score	0.467947 (rank : 53)
Query Neighborhood Hits	132	Target Neighborhood Hits	100	Shared Neighborhood Hits	80
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

GOGB1_HUMAN
θ value	0.0961366 (rank : 74)	NC score	0.025891 (rank : 105)
Query Neighborhood Hits	132	Target Neighborhood Hits	2297	Shared Neighborhood Hits	40
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

SKIV2_HUMAN
θ value	0.163984 (rank : 75)	NC score	0.121814 (rank : 90)
Query Neighborhood Hits	132	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	Q15477, O15005, Q12902, Q15476	Gene names	SKIV2L, DDX13, SKI2W, SKIV2, W
Domain Architecture
Description	Helicase SKI2W (EC 3.6.1.-) (Helicase-like protein) (HLP).

DDX28_MOUSE
θ value	0.21417 (rank : 76)	NC score	0.441229 (rank : 61)
Query Neighborhood Hits	132	Target Neighborhood Hits	112	Shared Neighborhood Hits	80
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

CENPE_HUMAN
θ value	0.279714 (rank : 77)	NC score	0.013175 (rank : 129)
Query Neighborhood Hits	132	Target Neighborhood Hits	2060	Shared Neighborhood Hits	34
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

DDX20_MOUSE
θ value	0.279714 (rank : 78)	NC score	0.431911 (rank : 65)
Query Neighborhood Hits	132	Target Neighborhood Hits	177	Shared Neighborhood Hits	80
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

JIP4_HUMAN
θ value	0.279714 (rank : 79)	NC score	0.026433 (rank : 104)
Query Neighborhood Hits	132	Target Neighborhood Hits	585	Shared Neighborhood Hits	23
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

DDX20_HUMAN
θ value	0.365318 (rank : 80)	NC score	0.434098 (rank : 64)
Query Neighborhood Hits	132	Target Neighborhood Hits	121	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

MYO5C_HUMAN
θ value	0.365318 (rank : 81)	NC score	0.014992 (rank : 123)
Query Neighborhood Hits	132	Target Neighborhood Hits	1206	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

LAMA3_MOUSE
θ value	0.47712 (rank : 82)	NC score	0.013282 (rank : 127)
Query Neighborhood Hits	132	Target Neighborhood Hits	859	Shared Neighborhood Hits	17
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

MY18A_MOUSE
θ value	0.47712 (rank : 83)	NC score	0.018825 (rank : 112)
Query Neighborhood Hits	132	Target Neighborhood Hits	1989	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SK2L2_HUMAN
θ value	0.47712 (rank : 84)	NC score	0.106149 (rank : 91)
Query Neighborhood Hits	132	Target Neighborhood Hits	36	Shared Neighborhood Hits	18
SwissProt Accessions	P42285, Q8TAG2	Gene names	SKIV2L2, KIAA0052
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SK2L2_MOUSE
θ value	0.47712 (rank : 85)	NC score	0.104504 (rank : 92)
Query Neighborhood Hits	132	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	Q9CZU3	Gene names	Skiv2l2
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

TAF1_HUMAN
θ value	0.47712 (rank : 86)	NC score	0.023699 (rank : 106)
Query Neighborhood Hits	132	Target Neighborhood Hits	136	Shared Neighborhood Hits	7
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

MY18A_HUMAN
θ value	0.62314 (rank : 87)	NC score	0.018277 (rank : 114)
Query Neighborhood Hits	132	Target Neighborhood Hits	1929	Shared Neighborhood Hits	44
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NEST_HUMAN
θ value	0.813845 (rank : 88)	NC score	0.019270 (rank : 111)
Query Neighborhood Hits	132	Target Neighborhood Hits	1305	Shared Neighborhood Hits	32
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

NOL8_HUMAN
θ value	0.813845 (rank : 89)	NC score	0.027775 (rank : 102)
Query Neighborhood Hits	132	Target Neighborhood Hits	297	Shared Neighborhood Hits	16
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

ZW10_MOUSE
θ value	0.813845 (rank : 90)	NC score	0.048378 (rank : 98)
Query Neighborhood Hits	132	Target Neighborhood Hits	86	Shared Neighborhood Hits	6
SwissProt Accessions	O54692, Q3TIA5, Q3ULW1, Q921H3	Gene names	Zw10
Domain Architecture	No domain graphic available
Description	Centromere/kinetochore protein zw10 homolog.

CENPF_HUMAN
θ value	1.06291 (rank : 91)	NC score	0.015252 (rank : 122)
Query Neighborhood Hits	132	Target Neighborhood Hits	1932	Shared Neighborhood Hits	36
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

ARI4A_HUMAN
θ value	1.38821 (rank : 92)	NC score	0.036542 (rank : 100)
Query Neighborhood Hits	132	Target Neighborhood Hits	434	Shared Neighborhood Hits	25
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

ANR26_MOUSE
θ value	1.81305 (rank : 93)	NC score	0.015912 (rank : 119)
Query Neighborhood Hits	132	Target Neighborhood Hits	1554	Shared Neighborhood Hits	34
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

DDX55_MOUSE
θ value	1.81305 (rank : 94)	NC score	0.415248 (rank : 74)
Query Neighborhood Hits	132	Target Neighborhood Hits	111	Shared Neighborhood Hits	79
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

FANCM_HUMAN
θ value	1.81305 (rank : 95)	NC score	0.208797 (rank : 80)
Query Neighborhood Hits	132	Target Neighborhood Hits	210	Shared Neighborhood Hits	79
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

IPP4_HUMAN
θ value	1.81305 (rank : 96)	NC score	0.029288 (rank : 101)
Query Neighborhood Hits	132	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	O14990, Q5H958	Gene names	PPP1R2P9
Domain Architecture	No domain graphic available
Description	Type-1 protein phosphatase inhibitor 4 (I-4) (Protein phosphatase 1, regulatory subunit 2 pseudogene 9).

ANR52_HUMAN
θ value	2.36792 (rank : 97)	NC score	0.009612 (rank : 135)
Query Neighborhood Hits	132	Target Neighborhood Hits	322	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_MOUSE
θ value	2.36792 (rank : 98)	NC score	0.009576 (rank : 136)
Query Neighborhood Hits	132	Target Neighborhood Hits	318	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

GCC2_MOUSE
θ value	2.36792 (rank : 99)	NC score	0.017298 (rank : 116)
Query Neighborhood Hits	132	Target Neighborhood Hits	1619	Shared Neighborhood Hits	35
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

RAD50_MOUSE
θ value	2.36792 (rank : 100)	NC score	0.015684 (rank : 120)
Query Neighborhood Hits	132	Target Neighborhood Hits	1366	Shared Neighborhood Hits	31
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

ANR12_HUMAN
θ value	3.0926 (rank : 101)	NC score	0.018379 (rank : 113)
Query Neighborhood Hits	132	Target Neighborhood Hits	1081	Shared Neighborhood Hits	34
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

ANR21_HUMAN
θ value	3.0926 (rank : 102)	NC score	0.013142 (rank : 130)
Query Neighborhood Hits	132	Target Neighborhood Hits	864	Shared Neighborhood Hits	31
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

IFIH1_MOUSE
θ value	3.0926 (rank : 103)	NC score	0.172870 (rank : 86)
Query Neighborhood Hits	132	Target Neighborhood Hits	126	Shared Neighborhood Hits	78
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

LEO1_MOUSE
θ value	3.0926 (rank : 104)	NC score	0.027129 (rank : 103)
Query Neighborhood Hits	132	Target Neighborhood Hits	946	Shared Neighborhood Hits	31
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

POT15_HUMAN
θ value	3.0926 (rank : 105)	NC score	0.013224 (rank : 128)
Query Neighborhood Hits	132	Target Neighborhood Hits	893	Shared Neighborhood Hits	34
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

TUR8_MOUSE
θ value	3.0926 (rank : 106)	NC score	0.055963 (rank : 96)
Query Neighborhood Hits	132	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	P19473	Gene names	Trap1a, P1a
Domain Architecture	No domain graphic available
Description	Tumor rejection antigen P815A.

CCDC6_HUMAN
θ value	4.03905 (rank : 107)	NC score	0.017445 (rank : 115)
Query Neighborhood Hits	132	Target Neighborhood Hits	723	Shared Neighborhood Hits	22
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

CR034_HUMAN
θ value	4.03905 (rank : 108)	NC score	0.019451 (rank : 110)
Query Neighborhood Hits	132	Target Neighborhood Hits	538	Shared Neighborhood Hits	20
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

DDX28_HUMAN
θ value	4.03905 (rank : 109)	NC score	0.424315 (rank : 71)
Query Neighborhood Hits	132	Target Neighborhood Hits	103	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX55_HUMAN
θ value	4.03905 (rank : 110)	NC score	0.411766 (rank : 75)
Query Neighborhood Hits	132	Target Neighborhood Hits	122	Shared Neighborhood Hits	79
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

MBB1A_MOUSE
θ value	4.03905 (rank : 111)	NC score	0.017173 (rank : 117)
Query Neighborhood Hits	132	Target Neighborhood Hits	233	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TPV4, O35851, Q80Y66, Q8R4X2, Q99KP0	Gene names	Mybbp1a, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A (Myb-binding protein of 160 kDa).

SYCP1_MOUSE
θ value	4.03905 (rank : 112)	NC score	0.017166 (rank : 118)
Query Neighborhood Hits	132	Target Neighborhood Hits	1456	Shared Neighborhood Hits	35
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

LAMA3_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.012524 (rank : 131)
Query Neighborhood Hits	132	Target Neighborhood Hits	760	Shared Neighborhood Hits	16
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

MAP4_HUMAN
θ value	5.27518 (rank : 114)	NC score	0.007925 (rank : 137)
Query Neighborhood Hits	132	Target Neighborhood Hits	428	Shared Neighborhood Hits	4
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

NSBP1_HUMAN
θ value	5.27518 (rank : 115)	NC score	0.019775 (rank : 109)
Query Neighborhood Hits	132	Target Neighborhood Hits	251	Shared Neighborhood Hits	16
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

NUB1_HUMAN
θ value	5.27518 (rank : 116)	NC score	0.013985 (rank : 126)
Query Neighborhood Hits	132	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5A7, O95422, Q8IX22, Q9BXR2	Gene names	NUB1, NYREN18
Domain Architecture
Description	NEDD8 ultimate buster 1 (NY-REN-18 antigen).

UBP1_HUMAN
θ value	5.27518 (rank : 117)	NC score	0.011103 (rank : 133)
Query Neighborhood Hits	132	Target Neighborhood Hits	259	Shared Neighborhood Hits	10
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

AN32A_MOUSE
θ value	6.88961 (rank : 118)	NC score	0.014203 (rank : 124)
Query Neighborhood Hits	132	Target Neighborhood Hits	254	Shared Neighborhood Hits	10
SwissProt Accessions	O35381, P97437	Gene names	Anp32a, Anp32, Lanp
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein).

AN32C_MOUSE
θ value	6.88961 (rank : 119)	NC score	0.014203 (rank : 125)
Query Neighborhood Hits	132	Target Neighborhood Hits	254	Shared Neighborhood Hits	10
SwissProt Accessions	Q64G17	Gene names	Anp32c
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member C.

CK5P2_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.020125 (rank : 108)
Query Neighborhood Hits	132	Target Neighborhood Hits	1433	Shared Neighborhood Hits	35
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

GCC1_MOUSE
θ value	6.88961 (rank : 121)	NC score	0.015587 (rank : 121)
Query Neighborhood Hits	132	Target Neighborhood Hits	777	Shared Neighborhood Hits	22
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

INVO_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.020148 (rank : 107)
Query Neighborhood Hits	132	Target Neighborhood Hits	636	Shared Neighborhood Hits	23
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

NEBU_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.007538 (rank : 138)
Query Neighborhood Hits	132	Target Neighborhood Hits	420	Shared Neighborhood Hits	12
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

ANK1_MOUSE
θ value	8.99809 (rank : 124)	NC score	0.004061 (rank : 140)
Query Neighborhood Hits	132	Target Neighborhood Hits	430	Shared Neighborhood Hits	10
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

BAZ2B_HUMAN
θ value	8.99809 (rank : 125)	NC score	0.010186 (rank : 134)
Query Neighborhood Hits	132	Target Neighborhood Hits	803	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

CG1_HUMAN
θ value	8.99809 (rank : 126)	NC score	0.011330 (rank : 132)
Query Neighborhood Hits	132	Target Neighborhood Hits	222	Shared Neighborhood Hits	4
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

DICER_HUMAN
θ value	8.99809 (rank : 127)	NC score	0.199851 (rank : 83)
Query Neighborhood Hits	132	Target Neighborhood Hits	126	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

DICER_MOUSE
θ value	8.99809 (rank : 128)	NC score	0.201951 (rank : 82)
Query Neighborhood Hits	132	Target Neighborhood Hits	140	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

NBEAL_HUMAN
θ value	8.99809 (rank : 129)	NC score	0.003912 (rank : 141)
Query Neighborhood Hits	132	Target Neighborhood Hits	200	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZS30, Q6Y876, Q6ZQY5, Q96Q30	Gene names	NBEAL1, ALS2CR17
Domain Architecture	No domain graphic available
Description	Neurobeachin-like 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein).

ROCK1_MOUSE
θ value	8.99809 (rank : 130)	NC score	0.002129 (rank : 142)
Query Neighborhood Hits	132	Target Neighborhood Hits	2126	Shared Neighborhood Hits	34
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

RP1_MOUSE
θ value	8.99809 (rank : 131)	NC score	0.006513 (rank : 139)
Query Neighborhood Hits	132	Target Neighborhood Hits	104	Shared Neighborhood Hits	3
SwissProt Accessions	P56716	Gene names	Rp1, Orp1, Rp1h
Domain Architecture
Description	Oxygen-regulated protein 1 (Retinitis pigmentosa RP1 protein homolog).

ZFP37_MOUSE
θ value	8.99809 (rank : 132)	NC score	-0.005283 (rank : 143)
Query Neighborhood Hits	132	Target Neighborhood Hits	906	Shared Neighborhood Hits	7
SwissProt Accessions	P17141, Q62514	Gene names	Zfp37, Zfp-37
Domain Architecture
Description	Zinc finger protein 37 (Zfp-37) (Male germ cell-specific zinc finger protein).

CC026_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.074635 (rank : 95)
Query Neighborhood Hits	132	Target Neighborhood Hits	39	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

CC026_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.055196 (rank : 97)
Query Neighborhood Hits	132	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

DDX53_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.473056 (rank : 44)
Query Neighborhood Hits	132	Target Neighborhood Hits	124	Shared Neighborhood Hits	75
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX56_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.396331 (rank : 77)
Query Neighborhood Hits	132	Target Neighborhood Hits	77	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DDX56_MOUSE
θ value	θ > 10 (rank : 137)	NC score	0.396880 (rank : 76)
Query Neighborhood Hits	132	Target Neighborhood Hits	87	Shared Neighborhood Hits	70
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX58_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.075358 (rank : 94)
Query Neighborhood Hits	132	Target Neighborhood Hits	105	Shared Neighborhood Hits	51
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DDX58_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.094545 (rank : 93)
Query Neighborhood Hits	132	Target Neighborhood Hits	99	Shared Neighborhood Hits	57
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

FANCM_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.203050 (rank : 81)
Query Neighborhood Hits	132	Target Neighborhood Hits	177	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

IFIH1_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.170861 (rank : 87)
Query Neighborhood Hits	132	Target Neighborhood Hits	96	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

LGP2_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.165871 (rank : 89)
Query Neighborhood Hits	132	Target Neighborhood Hits	94	Shared Neighborhood Hits	68
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

LGP2_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.169434 (rank : 88)
Query Neighborhood Hits	132	Target Neighborhood Hits	86	Shared Neighborhood Hits	65
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

Hits sorted by NC score

WRN_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	132	Target Neighborhood Hits	132	Shared Neighborhood Hits	132
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

WRN_MOUSE
NC score	0.960445 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	132	Target Neighborhood Hits	295	Shared Neighborhood Hits	91
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

RECQ1_MOUSE
NC score	0.876514 (rank : 3)	θ value	2.10232e-65 (rank : 4)
Query Neighborhood Hits	132	Target Neighborhood Hits	95	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ1_HUMAN
NC score	0.873212 (rank : 4)	θ value	9.43692e-66 (rank : 3)
Query Neighborhood Hits	132	Target Neighborhood Hits	100	Shared Neighborhood Hits	74
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

BLM_MOUSE
NC score	0.853674 (rank : 5)	θ value	3.84025e-59 (rank : 5)
Query Neighborhood Hits	132	Target Neighborhood Hits	108	Shared Neighborhood Hits	71
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

BLM_HUMAN
NC score	0.846533 (rank : 6)	θ value	1.61343e-57 (rank : 6)
Query Neighborhood Hits	132	Target Neighborhood Hits	148	Shared Neighborhood Hits	76
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

RECQ5_HUMAN
NC score	0.820234 (rank : 7)	θ value	1.51013e-55 (rank : 7)
Query Neighborhood Hits	132	Target Neighborhood Hits	390	Shared Neighborhood Hits	73
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

RECQ4_HUMAN
NC score	0.808735 (rank : 8)	θ value	3.61106e-41 (rank : 8)
Query Neighborhood Hits	132	Target Neighborhood Hits	177	Shared Neighborhood Hits	83
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RECQ4_MOUSE
NC score	0.799419 (rank : 9)	θ value	5.21438e-40 (rank : 9)
Query Neighborhood Hits	132	Target Neighborhood Hits	206	Shared Neighborhood Hits	83
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

DDX17_MOUSE
NC score	0.522630 (rank : 10)	θ value	1.06045e-08 (rank : 18)
Query Neighborhood Hits	132	Target Neighborhood Hits	105	Shared Neighborhood Hits	78
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX17_HUMAN
NC score	0.522558 (rank : 11)	θ value	1.06045e-08 (rank : 17)
Query Neighborhood Hits	132	Target Neighborhood Hits	104	Shared Neighborhood Hits	78
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX5_MOUSE
NC score	0.518247 (rank : 12)	θ value	2.61198e-07 (rank : 25)
Query Neighborhood Hits	132	Target Neighborhood Hits	101	Shared Neighborhood Hits	78
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX46_HUMAN
NC score	0.518026 (rank : 13)	θ value	1.63604e-09 (rank : 10)
Query Neighborhood Hits	132	Target Neighborhood Hits	357	Shared Neighborhood Hits	92
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
NC score	0.517809 (rank : 14)	θ value	1.63604e-09 (rank : 11)
Query Neighborhood Hits	132	Target Neighborhood Hits	358	Shared Neighborhood Hits	92
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX5_HUMAN
NC score	0.517767 (rank : 15)	θ value	2.61198e-07 (rank : 24)
Query Neighborhood Hits	132	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX43_HUMAN
NC score	0.506150 (rank : 16)	θ value	1.29631e-06 (rank : 26)
Query Neighborhood Hits	132	Target Neighborhood Hits	120	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX52_MOUSE
NC score	0.504129 (rank : 17)	θ value	1.17247e-07 (rank : 21)
Query Neighborhood Hits	132	Target Neighborhood Hits	101	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX41_HUMAN
NC score	0.503986 (rank : 18)	θ value	1.43324e-05 (rank : 38)
Query Neighborhood Hits	132	Target Neighborhood Hits	111	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX6_HUMAN
NC score	0.503859 (rank : 19)	θ value	2.21117e-06 (rank : 28)
Query Neighborhood Hits	132	Target Neighborhood Hits	97	Shared Neighborhood Hits	82
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
NC score	0.503758 (rank : 20)	θ value	2.21117e-06 (rank : 29)
Query Neighborhood Hits	132	Target Neighborhood Hits	98	Shared Neighborhood Hits	82
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX52_HUMAN
NC score	0.503053 (rank : 21)	θ value	1.69304e-06 (rank : 27)
Query Neighborhood Hits	132	Target Neighborhood Hits	107	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX3X_MOUSE
NC score	0.503051 (rank : 22)	θ value	3.64472e-09 (rank : 13)
Query Neighborhood Hits	132	Target Neighborhood Hits	117	Shared Neighborhood Hits	78
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX41_MOUSE
NC score	0.502209 (rank : 23)	θ value	1.43324e-05 (rank : 39)
Query Neighborhood Hits	132	Target Neighborhood Hits	115	Shared Neighborhood Hits	79
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX3X_HUMAN
NC score	0.501528 (rank : 24)	θ value	8.11959e-09 (rank : 16)
Query Neighborhood Hits	132	Target Neighborhood Hits	122	Shared Neighborhood Hits	79
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX3Y_HUMAN
NC score	0.500361 (rank : 25)	θ value	8.97725e-08 (rank : 20)
Query Neighborhood Hits	132	Target Neighborhood Hits	121	Shared Neighborhood Hits	78
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

PL10_MOUSE
NC score	0.499734 (rank : 26)	θ value	4.0297e-08 (rank : 19)
Query Neighborhood Hits	132	Target Neighborhood Hits	120	Shared Neighborhood Hits	78
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3Y_MOUSE
NC score	0.498683 (rank : 27)	θ value	2.13673e-09 (rank : 12)
Query Neighborhood Hits	132	Target Neighborhood Hits	126	Shared Neighborhood Hits	79
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX50_HUMAN
NC score	0.498627 (rank : 28)	θ value	1.43324e-05 (rank : 40)
Query Neighborhood Hits	132	Target Neighborhood Hits	132	Shared Neighborhood Hits	81
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_MOUSE
NC score	0.498458 (rank : 29)	θ value	1.43324e-05 (rank : 41)
Query Neighborhood Hits	132	Target Neighborhood Hits	137	Shared Neighborhood Hits	81
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX48_HUMAN
NC score	0.494201 (rank : 30)	θ value	1.99992e-07 (rank : 22)
Query Neighborhood Hits	132	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
NC score	0.493998 (rank : 31)	θ value	1.99992e-07 (rank : 23)
Query Neighborhood Hits	132	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX23_HUMAN
NC score	0.491591 (rank : 32)	θ value	6.43352e-06 (rank : 33)
Query Neighborhood Hits	132	Target Neighborhood Hits	486	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX49_MOUSE
NC score	0.488640 (rank : 33)	θ value	4.1701e-05 (rank : 44)
Query Neighborhood Hits	132	Target Neighborhood Hits	119	Shared Neighborhood Hits	81
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX21_HUMAN
NC score	0.488400 (rank : 34)	θ value	0.000158464 (rank : 45)
Query Neighborhood Hits	132	Target Neighborhood Hits	308	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX49_HUMAN
NC score	0.484959 (rank : 35)	θ value	4.1701e-05 (rank : 43)
Query Neighborhood Hits	132	Target Neighborhood Hits	223	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

IF4A2_HUMAN
NC score	0.479660 (rank : 36)	θ value	1.09739e-05 (rank : 36)
Query Neighborhood Hits	132	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
NC score	0.479660 (rank : 37)	θ value	1.09739e-05 (rank : 37)
Query Neighborhood Hits	132	Target Neighborhood Hits	102	Shared Neighborhood Hits	78
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A1_HUMAN
NC score	0.479053 (rank : 38)	θ value	4.92598e-06 (rank : 31)
Query Neighborhood Hits	132	Target Neighborhood Hits	106	Shared Neighborhood Hits	78
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
NC score	0.479053 (rank : 39)	θ value	4.92598e-06 (rank : 32)
Query Neighborhood Hits	132	Target Neighborhood Hits	106	Shared Neighborhood Hits	78
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

DDX21_MOUSE
NC score	0.478780 (rank : 40)	θ value	0.00102713 (rank : 49)
Query Neighborhood Hits	132	Target Neighborhood Hits	350	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX27_MOUSE
NC score	0.477661 (rank : 41)	θ value	0.000270298 (rank : 46)
Query Neighborhood Hits	132	Target Neighborhood Hits	174	Shared Neighborhood Hits	84
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_HUMAN
NC score	0.474744 (rank : 42)	θ value	0.000461057 (rank : 47)
Query Neighborhood Hits	132	Target Neighborhood Hits	197	Shared Neighborhood Hits	83
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX54_MOUSE
NC score	0.474014 (rank : 43)	θ value	2.88788e-06 (rank : 30)
Query Neighborhood Hits	132	Target Neighborhood Hits	124	Shared Neighborhood Hits	82
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX53_HUMAN
NC score	0.473056 (rank : 44)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	132	Target Neighborhood Hits	124	Shared Neighborhood Hits	75
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX47_HUMAN
NC score	0.472446 (rank : 45)	θ value	0.00102713 (rank : 51)
Query Neighborhood Hits	132	Target Neighborhood Hits	97	Shared Neighborhood Hits	78
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_MOUSE
NC score	0.472215 (rank : 46)	θ value	0.00102713 (rank : 52)
Query Neighborhood Hits	132	Target Neighborhood Hits	97	Shared Neighborhood Hits	78
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX54_HUMAN
NC score	0.470921 (rank : 47)	θ value	6.43352e-06 (rank : 34)
Query Neighborhood Hits	132	Target Neighborhood Hits	170	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX39_HUMAN
NC score	0.470393 (rank : 48)	θ value	0.000786445 (rank : 48)
Query Neighborhood Hits	132	Target Neighborhood Hits	94	Shared Neighborhood Hits	78
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX24_MOUSE
NC score	0.470188 (rank : 49)	θ value	2.44474e-05 (rank : 42)
Query Neighborhood Hits	132	Target Neighborhood Hits	147	Shared Neighborhood Hits	81
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX24_HUMAN
NC score	0.468722 (rank : 50)	θ value	8.40245e-06 (rank : 35)
Query Neighborhood Hits	132	Target Neighborhood Hits	190	Shared Neighborhood Hits	83
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX4_HUMAN
NC score	0.468543 (rank : 51)	θ value	0.0961366 (rank : 72)
Query Neighborhood Hits	132	Target Neighborhood Hits	123	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX39_MOUSE
NC score	0.468102 (rank : 52)	θ value	0.00102713 (rank : 50)
Query Neighborhood Hits	132	Target Neighborhood Hits	97	Shared Neighborhood Hits	78
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX4_MOUSE
NC score	0.467947 (rank : 53)	θ value	0.0961366 (rank : 73)
Query Neighborhood Hits	132	Target Neighborhood Hits	100	Shared Neighborhood Hits	80
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

UAP56_HUMAN
NC score	0.460563 (rank : 54)	θ value	0.00869519 (rank : 59)
Query Neighborhood Hits	132	Target Neighborhood Hits	96	Shared Neighborhood Hits	78
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
NC score	0.460418 (rank : 55)	θ value	0.00869519 (rank : 60)
Query Neighborhood Hits	132	Target Neighborhood Hits	96	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX31_HUMAN
NC score	0.457015 (rank : 56)	θ value	0.00665767 (rank : 57)
Query Neighborhood Hits	132	Target Neighborhood Hits	132	Shared Neighborhood Hits	80
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX10_HUMAN
NC score	0.449890 (rank : 57)	θ value	0.00665767 (rank : 56)
Query Neighborhood Hits	132	Target Neighborhood Hits	210	Shared Neighborhood Hits	87
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX51_MOUSE
NC score	0.449408 (rank : 58)	θ value	0.00228821 (rank : 54)
Query Neighborhood Hits	132	Target Neighborhood Hits	130	Shared Neighborhood Hits	80
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX51_HUMAN
NC score	0.446955 (rank : 59)	θ value	0.00509761 (rank : 55)
Query Neighborhood Hits	132	Target Neighborhood Hits	332	Shared Neighborhood Hits	81
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX10_MOUSE
NC score	0.446347 (rank : 60)	θ value	0.0193708 (rank : 66)
Query Neighborhood Hits	132	Target Neighborhood Hits	233	Shared Neighborhood Hits	88
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX28_MOUSE
NC score	0.441229 (rank : 61)	θ value	0.21417 (rank : 76)
Query Neighborhood Hits	132	Target Neighborhood Hits	112	Shared Neighborhood Hits	80
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX1_MOUSE
NC score	0.440995 (rank : 62)	θ value	0.0961366 (rank : 71)
Query Neighborhood Hits	132	Target Neighborhood Hits	112	Shared Neighborhood Hits	77
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX1_HUMAN
NC score	0.438139 (rank : 63)	θ value	0.0961366 (rank : 70)
Query Neighborhood Hits	132	Target Neighborhood Hits	110	Shared Neighborhood Hits	77
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX20_HUMAN
NC score	0.434098 (rank : 64)	θ value	0.365318 (rank : 80)
Query Neighborhood Hits	132	Target Neighborhood Hits	121	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX20_MOUSE
NC score	0.431911 (rank : 65)	θ value	0.279714 (rank : 78)
Query Neighborhood Hits	132	Target Neighborhood Hits	177	Shared Neighborhood Hits	80
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX18_HUMAN
NC score	0.430809 (rank : 66)	θ value	0.00175202 (rank : 53)
Query Neighborhood Hits	132	Target Neighborhood Hits	124	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DD19A_HUMAN
NC score	0.430260 (rank : 67)	θ value	0.0148317 (rank : 62)
Query Neighborhood Hits	132	Target Neighborhood Hits	107	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19B_HUMAN
NC score	0.430021 (rank : 68)	θ value	0.0148317 (rank : 64)
Query Neighborhood Hits	132	Target Neighborhood Hits	109	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DD19A_MOUSE
NC score	0.429198 (rank : 69)	θ value	0.0148317 (rank : 63)
Query Neighborhood Hits	132	Target Neighborhood Hits	105	Shared Neighborhood Hits	76
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DDX25_HUMAN
NC score	0.426105 (rank : 70)	θ value	0.0193708 (rank : 67)
Query Neighborhood Hits	132	Target Neighborhood Hits	93	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX28_HUMAN
NC score	0.424315 (rank : 71)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	132	Target Neighborhood Hits	103	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX25_MOUSE
NC score	0.423939 (rank : 72)	θ value	0.0113563 (rank : 61)
Query Neighborhood Hits	132	Target Neighborhood Hits	98	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX18_MOUSE
NC score	0.421894 (rank : 73)	θ value	0.0736092 (rank : 68)
Query Neighborhood Hits	132	Target Neighborhood Hits	115	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX55_MOUSE
NC score	0.415248 (rank : 74)	θ value	1.81305 (rank : 94)
Query Neighborhood Hits	132	Target Neighborhood Hits	111	Shared Neighborhood Hits	79
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX55_HUMAN
NC score	0.411766 (rank : 75)	θ value	4.03905 (rank : 110)
Query Neighborhood Hits	132	Target Neighborhood Hits	122	Shared Neighborhood Hits	79
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX56_MOUSE
NC score	0.396880 (rank : 76)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	132	Target Neighborhood Hits	87	Shared Neighborhood Hits	70
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX56_HUMAN
NC score	0.396331 (rank : 77)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	132	Target Neighborhood Hits	77	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

EXDL2_HUMAN
NC score	0.254095 (rank : 78)	θ value	3.64472e-09 (rank : 14)
Query Neighborhood Hits	132	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NVH0, Q8N3D3	Gene names	EXDL2, C14orf114
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.

EXDL2_MOUSE
NC score	0.250269 (rank : 79)	θ value	3.64472e-09 (rank : 15)
Query Neighborhood Hits	132	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VEG4	Gene names	Exdl2
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.

FANCM_HUMAN
NC score	0.208797 (rank : 80)	θ value	1.81305 (rank : 95)
Query Neighborhood Hits	132	Target Neighborhood Hits	210	Shared Neighborhood Hits	79
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

FANCM_MOUSE
NC score	0.203050 (rank : 81)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	132	Target Neighborhood Hits	177	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

DICER_MOUSE
NC score	0.201951 (rank : 82)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	132	Target Neighborhood Hits	140	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

DICER_HUMAN
NC score	0.199851 (rank : 83)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	132	Target Neighborhood Hits	126	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

U520_HUMAN
NC score	0.198409 (rank : 84)	θ value	0.0148317 (rank : 65)
Query Neighborhood Hits	132	Target Neighborhood Hits	88	Shared Neighborhood Hits	45
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

HELC1_HUMAN
NC score	0.178648 (rank : 85)	θ value	0.00869519 (rank : 58)
Query Neighborhood Hits	132	Target Neighborhood Hits	71	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

IFIH1_MOUSE
NC score	0.172870 (rank : 86)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	132	Target Neighborhood Hits	126	Shared Neighborhood Hits	78
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

IFIH1_HUMAN
NC score	0.170861 (rank : 87)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	132	Target Neighborhood Hits	96	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

LGP2_MOUSE
NC score	0.169434 (rank : 88)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	132	Target Neighborhood Hits	86	Shared Neighborhood Hits	65
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

LGP2_HUMAN
NC score	0.165871 (rank : 89)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	132	Target Neighborhood Hits	94	Shared Neighborhood Hits	68
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

SKIV2_HUMAN
NC score	0.121814 (rank : 90)	θ value	0.163984 (rank : 75)
Query Neighborhood Hits	132	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	Q15477, O15005, Q12902, Q15476	Gene names	SKIV2L, DDX13, SKI2W, SKIV2, W
Domain Architecture
Description	Helicase SKI2W (EC 3.6.1.-) (Helicase-like protein) (HLP).

SK2L2_HUMAN
NC score	0.106149 (rank : 91)	θ value	0.47712 (rank : 84)
Query Neighborhood Hits	132	Target Neighborhood Hits	36	Shared Neighborhood Hits	18
SwissProt Accessions	P42285, Q8TAG2	Gene names	SKIV2L2, KIAA0052
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SK2L2_MOUSE
NC score	0.104504 (rank : 92)	θ value	0.47712 (rank : 85)
Query Neighborhood Hits	132	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	Q9CZU3	Gene names	Skiv2l2
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

DDX58_MOUSE
NC score	0.094545 (rank : 93)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	132	Target Neighborhood Hits	99	Shared Neighborhood Hits	57
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DDX58_HUMAN
NC score	0.075358 (rank : 94)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	132	Target Neighborhood Hits	105	Shared Neighborhood Hits	51
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

CC026_HUMAN
NC score	0.074635 (rank : 95)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	132	Target Neighborhood Hits	39	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

TUR8_MOUSE
NC score	0.055963 (rank : 96)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	132	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	P19473	Gene names	Trap1a, P1a
Domain Architecture	No domain graphic available
Description	Tumor rejection antigen P815A.

CC026_MOUSE
NC score	0.055196 (rank : 97)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	132	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

ZW10_MOUSE
NC score	0.048378 (rank : 98)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	132	Target Neighborhood Hits	86	Shared Neighborhood Hits	6
SwissProt Accessions	O54692, Q3TIA5, Q3ULW1, Q921H3	Gene names	Zw10
Domain Architecture	No domain graphic available
Description	Centromere/kinetochore protein zw10 homolog.

MTO1_MOUSE
NC score	0.044484 (rank : 99)	θ value	0.0736092 (rank : 69)
Query Neighborhood Hits	132	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q923Z3, Q9D2Q5	Gene names	Mto1
Domain Architecture	No domain graphic available
Description	Protein MTO1 homolog, mitochondrial precursor.

ARI4A_HUMAN
NC score	0.036542 (rank : 100)	θ value	1.38821 (rank : 92)
Query Neighborhood Hits	132	Target Neighborhood Hits	434	Shared Neighborhood Hits	25
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

IPP4_HUMAN
NC score	0.029288 (rank : 101)	θ value	1.81305 (rank : 96)
Query Neighborhood Hits	132	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	O14990, Q5H958	Gene names	PPP1R2P9
Domain Architecture	No domain graphic available
Description	Type-1 protein phosphatase inhibitor 4 (I-4) (Protein phosphatase 1, regulatory subunit 2 pseudogene 9).

NOL8_HUMAN
NC score	0.027775 (rank : 102)	θ value	0.813845 (rank : 89)
Query Neighborhood Hits	132	Target Neighborhood Hits	297	Shared Neighborhood Hits	16
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

LEO1_MOUSE
NC score	0.027129 (rank : 103)	θ value	3.0926 (rank : 104)
Query Neighborhood Hits	132	Target Neighborhood Hits	946	Shared Neighborhood Hits	31
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

JIP4_HUMAN
NC score	0.026433 (rank : 104)	θ value	0.279714 (rank : 79)
Query Neighborhood Hits	132	Target Neighborhood Hits	585	Shared Neighborhood Hits	23
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

GOGB1_HUMAN
NC score	0.025891 (rank : 105)	θ value	0.0961366 (rank : 74)
Query Neighborhood Hits	132	Target Neighborhood Hits	2297	Shared Neighborhood Hits	40
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

TAF1_HUMAN
NC score	0.023699 (rank : 106)	θ value	0.47712 (rank : 86)
Query Neighborhood Hits	132	Target Neighborhood Hits	136	Shared Neighborhood Hits	7
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

INVO_HUMAN
NC score	0.020148 (rank : 107)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	132	Target Neighborhood Hits	636	Shared Neighborhood Hits	23
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

CK5P2_HUMAN
NC score	0.020125 (rank : 108)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	132	Target Neighborhood Hits	1433	Shared Neighborhood Hits	35
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

NSBP1_HUMAN
NC score	0.019775 (rank : 109)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	132	Target Neighborhood Hits	251	Shared Neighborhood Hits	16
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

CR034_HUMAN
NC score	0.019451 (rank : 110)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	132	Target Neighborhood Hits	538	Shared Neighborhood Hits	20
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

NEST_HUMAN
NC score	0.019270 (rank : 111)	θ value	0.813845 (rank : 88)
Query Neighborhood Hits	132	Target Neighborhood Hits	1305	Shared Neighborhood Hits	32
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

MY18A_MOUSE
NC score	0.018825 (rank : 112)	θ value	0.47712 (rank : 83)
Query Neighborhood Hits	132	Target Neighborhood Hits	1989	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

ANR12_HUMAN
NC score	0.018379 (rank : 113)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	132	Target Neighborhood Hits	1081	Shared Neighborhood Hits	34
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

MY18A_HUMAN
NC score	0.018277 (rank : 114)	θ value	0.62314 (rank : 87)
Query Neighborhood Hits	132	Target Neighborhood Hits	1929	Shared Neighborhood Hits	44
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CCDC6_HUMAN
NC score	0.017445 (rank : 115)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	132	Target Neighborhood Hits	723	Shared Neighborhood Hits	22
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

GCC2_MOUSE
NC score	0.017298 (rank : 116)	θ value	2.36792 (rank : 99)
Query Neighborhood Hits	132	Target Neighborhood Hits	1619	Shared Neighborhood Hits	35
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

MBB1A_MOUSE
NC score	0.017173 (rank : 117)	θ value	4.03905 (rank : 111)
Query Neighborhood Hits	132	Target Neighborhood Hits	233	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TPV4, O35851, Q80Y66, Q8R4X2, Q99KP0	Gene names	Mybbp1a, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A (Myb-binding protein of 160 kDa).

SYCP1_MOUSE
NC score	0.017166 (rank : 118)	θ value	4.03905 (rank : 112)
Query Neighborhood Hits	132	Target Neighborhood Hits	1456	Shared Neighborhood Hits	35
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

ANR26_MOUSE
NC score	0.015912 (rank : 119)	θ value	1.81305 (rank : 93)
Query Neighborhood Hits	132	Target Neighborhood Hits	1554	Shared Neighborhood Hits	34
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

RAD50_MOUSE
NC score	0.015684 (rank : 120)	θ value	2.36792 (rank : 100)
Query Neighborhood Hits	132	Target Neighborhood Hits	1366	Shared Neighborhood Hits	31
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

GCC1_MOUSE
NC score	0.015587 (rank : 121)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	132	Target Neighborhood Hits	777	Shared Neighborhood Hits	22
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

CENPF_HUMAN
NC score	0.015252 (rank : 122)	θ value	1.06291 (rank : 91)
Query Neighborhood Hits	132	Target Neighborhood Hits	1932	Shared Neighborhood Hits	36
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

MYO5C_HUMAN
NC score	0.014992 (rank : 123)	θ value	0.365318 (rank : 81)
Query Neighborhood Hits	132	Target Neighborhood Hits	1206	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

AN32A_MOUSE
NC score	0.014203 (rank : 124)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	132	Target Neighborhood Hits	254	Shared Neighborhood Hits	10
SwissProt Accessions	O35381, P97437	Gene names	Anp32a, Anp32, Lanp
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein).

AN32C_MOUSE
NC score	0.014203 (rank : 125)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	132	Target Neighborhood Hits	254	Shared Neighborhood Hits	10
SwissProt Accessions	Q64G17	Gene names	Anp32c
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member C.

NUB1_HUMAN
NC score	0.013985 (rank : 126)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	132	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5A7, O95422, Q8IX22, Q9BXR2	Gene names	NUB1, NYREN18
Domain Architecture
Description	NEDD8 ultimate buster 1 (NY-REN-18 antigen).

LAMA3_MOUSE
NC score	0.013282 (rank : 127)	θ value	0.47712 (rank : 82)
Query Neighborhood Hits	132	Target Neighborhood Hits	859	Shared Neighborhood Hits	17
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

POT15_HUMAN
NC score	0.013224 (rank : 128)	θ value	3.0926 (rank : 105)
Query Neighborhood Hits	132	Target Neighborhood Hits	893	Shared Neighborhood Hits	34
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

CENPE_HUMAN
NC score	0.013175 (rank : 129)	θ value	0.279714 (rank : 77)
Query Neighborhood Hits	132	Target Neighborhood Hits	2060	Shared Neighborhood Hits	34
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

ANR21_HUMAN
NC score	0.013142 (rank : 130)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	132	Target Neighborhood Hits	864	Shared Neighborhood Hits	31
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

LAMA3_HUMAN
NC score	0.012524 (rank : 131)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	132	Target Neighborhood Hits	760	Shared Neighborhood Hits	16
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

CG1_HUMAN
NC score	0.011330 (rank : 132)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	132	Target Neighborhood Hits	222	Shared Neighborhood Hits	4
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

UBP1_HUMAN
NC score	0.011103 (rank : 133)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	132	Target Neighborhood Hits	259	Shared Neighborhood Hits	10
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

BAZ2B_HUMAN
NC score	0.010186 (rank : 134)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	132	Target Neighborhood Hits	803	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

ANR52_HUMAN
NC score	0.009612 (rank : 135)	θ value	2.36792 (rank : 97)
Query Neighborhood Hits	132	Target Neighborhood Hits	322	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_MOUSE
NC score	0.009576 (rank : 136)	θ value	2.36792 (rank : 98)
Query Neighborhood Hits	132	Target Neighborhood Hits	318	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

MAP4_HUMAN
NC score	0.007925 (rank : 137)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	132	Target Neighborhood Hits	428	Shared Neighborhood Hits	4
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

NEBU_HUMAN
NC score	0.007538 (rank : 138)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	132	Target Neighborhood Hits	420	Shared Neighborhood Hits	12
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

RP1_MOUSE
NC score	0.006513 (rank : 139)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	132	Target Neighborhood Hits	104	Shared Neighborhood Hits	3
SwissProt Accessions	P56716	Gene names	Rp1, Orp1, Rp1h
Domain Architecture
Description	Oxygen-regulated protein 1 (Retinitis pigmentosa RP1 protein homolog).

ANK1_MOUSE
NC score	0.004061 (rank : 140)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	132	Target Neighborhood Hits	430	Shared Neighborhood Hits	10
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

NBEAL_HUMAN
NC score	0.003912 (rank : 141)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	132	Target Neighborhood Hits	200	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZS30, Q6Y876, Q6ZQY5, Q96Q30	Gene names	NBEAL1, ALS2CR17
Domain Architecture	No domain graphic available
Description	Neurobeachin-like 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein).

ROCK1_MOUSE
NC score	0.002129 (rank : 142)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	132	Target Neighborhood Hits	2126	Shared Neighborhood Hits	34
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

ZFP37_MOUSE
NC score	-0.005283 (rank : 143)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	132	Target Neighborhood Hits	906	Shared Neighborhood Hits	7
SwissProt Accessions	P17141, Q62514	Gene names	Zfp37, Zfp-37
Domain Architecture
Description	Zinc finger protein 37 (Zfp-37) (Male germ cell-specific zinc finger protein).