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Network neighborhood for query Sequence : DDX27_MOUSE

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DDX27_MOUSE
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DDX27_HUMAN
θ value	0 (rank : 1)	NC score	0.995483 (rank : 2)
Query Neighborhood Hits	174	Target Neighborhood Hits	197	Shared Neighborhood Hits	128
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	174	Target Neighborhood Hits	174	Shared Neighborhood Hits	174
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX47_HUMAN
θ value	1.7756e-72 (rank : 3)	NC score	0.978797 (rank : 4)
Query Neighborhood Hits	174	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_MOUSE
θ value	6.31527e-70 (rank : 4)	NC score	0.978946 (rank : 3)
Query Neighborhood Hits	174	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX49_HUMAN
θ value	1.45591e-66 (rank : 5)	NC score	0.973045 (rank : 6)
Query Neighborhood Hits	174	Target Neighborhood Hits	223	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX49_MOUSE
θ value	1.36269e-64 (rank : 6)	NC score	0.976679 (rank : 5)
Query Neighborhood Hits	174	Target Neighborhood Hits	119	Shared Neighborhood Hits	87
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX54_MOUSE
θ value	4.53632e-60 (rank : 7)	NC score	0.965443 (rank : 7)
Query Neighborhood Hits	174	Target Neighborhood Hits	124	Shared Neighborhood Hits	85
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX18_MOUSE
θ value	3.974e-56 (rank : 8)	NC score	0.962077 (rank : 14)
Query Neighborhood Hits	174	Target Neighborhood Hits	115	Shared Neighborhood Hits	79
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX54_HUMAN
θ value	5.19021e-56 (rank : 9)	NC score	0.961595 (rank : 15)
Query Neighborhood Hits	174	Target Neighborhood Hits	170	Shared Neighborhood Hits	87
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX10_HUMAN
θ value	5.73848e-55 (rank : 10)	NC score	0.957863 (rank : 28)
Query Neighborhood Hits	174	Target Neighborhood Hits	210	Shared Neighborhood Hits	98
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

PL10_MOUSE
θ value	9.78833e-55 (rank : 11)	NC score	0.953283 (rank : 40)
Query Neighborhood Hits	174	Target Neighborhood Hits	120	Shared Neighborhood Hits	90
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3X_HUMAN
θ value	1.2784e-54 (rank : 12)	NC score	0.953157 (rank : 41)
Query Neighborhood Hits	174	Target Neighborhood Hits	122	Shared Neighborhood Hits	91
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX23_HUMAN
θ value	8.28633e-54 (rank : 13)	NC score	0.942058 (rank : 54)
Query Neighborhood Hits	174	Target Neighborhood Hits	486	Shared Neighborhood Hits	127
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX3X_MOUSE
θ value	1.41344e-53 (rank : 14)	NC score	0.952540 (rank : 45)
Query Neighborhood Hits	174	Target Neighborhood Hits	117	Shared Neighborhood Hits	90
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX3Y_HUMAN
θ value	1.84601e-53 (rank : 15)	NC score	0.951618 (rank : 48)
Query Neighborhood Hits	174	Target Neighborhood Hits	121	Shared Neighborhood Hits	90
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX10_MOUSE
θ value	3.1488e-53 (rank : 16)	NC score	0.956570 (rank : 37)
Query Neighborhood Hits	174	Target Neighborhood Hits	233	Shared Neighborhood Hits	95
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX4_HUMAN
θ value	9.16162e-53 (rank : 17)	NC score	0.960567 (rank : 17)
Query Neighborhood Hits	174	Target Neighborhood Hits	123	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX18_HUMAN
θ value	7.75577e-52 (rank : 18)	NC score	0.960382 (rank : 18)
Query Neighborhood Hits	174	Target Neighborhood Hits	124	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX4_MOUSE
θ value	1.32293e-51 (rank : 19)	NC score	0.961232 (rank : 16)
Query Neighborhood Hits	174	Target Neighborhood Hits	100	Shared Neighborhood Hits	86
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX3Y_MOUSE
θ value	5.02714e-51 (rank : 20)	NC score	0.952714 (rank : 44)
Query Neighborhood Hits	174	Target Neighborhood Hits	126	Shared Neighborhood Hits	90
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

UAP56_MOUSE
θ value	2.49495e-50 (rank : 21)	NC score	0.957781 (rank : 30)
Query Neighborhood Hits	174	Target Neighborhood Hits	96	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX53_HUMAN
θ value	5.55816e-50 (rank : 22)	NC score	0.955971 (rank : 38)
Query Neighborhood Hits	174	Target Neighborhood Hits	124	Shared Neighborhood Hits	82
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

UAP56_HUMAN
θ value	7.25919e-50 (rank : 23)	NC score	0.957803 (rank : 29)
Query Neighborhood Hits	174	Target Neighborhood Hits	96	Shared Neighborhood Hits	85
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

DDX39_HUMAN
θ value	9.48078e-50 (rank : 24)	NC score	0.959462 (rank : 22)
Query Neighborhood Hits	174	Target Neighborhood Hits	94	Shared Neighborhood Hits	86
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX48_HUMAN
θ value	1.61718e-49 (rank : 25)	NC score	0.960188 (rank : 20)
Query Neighborhood Hits	174	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
θ value	2.1121e-49 (rank : 26)	NC score	0.960009 (rank : 21)
Query Neighborhood Hits	174	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX51_MOUSE
θ value	8.02596e-49 (rank : 27)	NC score	0.951820 (rank : 47)
Query Neighborhood Hits	174	Target Neighborhood Hits	130	Shared Neighborhood Hits	87
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX39_MOUSE
θ value	1.36902e-48 (rank : 28)	NC score	0.958638 (rank : 23)
Query Neighborhood Hits	174	Target Neighborhood Hits	97	Shared Neighborhood Hits	85
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX17_HUMAN
θ value	1.788e-48 (rank : 29)	NC score	0.957335 (rank : 35)
Query Neighborhood Hits	174	Target Neighborhood Hits	104	Shared Neighborhood Hits	87
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX17_MOUSE
θ value	1.788e-48 (rank : 30)	NC score	0.957472 (rank : 34)
Query Neighborhood Hits	174	Target Neighborhood Hits	105	Shared Neighborhood Hits	87
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX5_HUMAN
θ value	3.04986e-48 (rank : 31)	NC score	0.952986 (rank : 42)
Query Neighborhood Hits	174	Target Neighborhood Hits	102	Shared Neighborhood Hits	87
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

IF4A1_HUMAN
θ value	3.98324e-48 (rank : 32)	NC score	0.957887 (rank : 26)
Query Neighborhood Hits	174	Target Neighborhood Hits	106	Shared Neighborhood Hits	86
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
θ value	3.98324e-48 (rank : 33)	NC score	0.957887 (rank : 27)
Query Neighborhood Hits	174	Target Neighborhood Hits	106	Shared Neighborhood Hits	86
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A2_HUMAN
θ value	6.7944e-48 (rank : 34)	NC score	0.957627 (rank : 32)
Query Neighborhood Hits	174	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
θ value	6.7944e-48 (rank : 35)	NC score	0.957627 (rank : 33)
Query Neighborhood Hits	174	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX5_MOUSE
θ value	8.87376e-48 (rank : 36)	NC score	0.952848 (rank : 43)
Query Neighborhood Hits	174	Target Neighborhood Hits	101	Shared Neighborhood Hits	87
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX51_HUMAN
θ value	2.58187e-47 (rank : 37)	NC score	0.936834 (rank : 63)
Query Neighborhood Hits	174	Target Neighborhood Hits	332	Shared Neighborhood Hits	90
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX52_HUMAN
θ value	2.58187e-47 (rank : 38)	NC score	0.965118 (rank : 8)
Query Neighborhood Hits	174	Target Neighborhood Hits	107	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX41_MOUSE
θ value	2.85459e-46 (rank : 39)	NC score	0.963113 (rank : 13)
Query Neighborhood Hits	174	Target Neighborhood Hits	115	Shared Neighborhood Hits	90
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX41_HUMAN
θ value	3.72821e-46 (rank : 40)	NC score	0.963414 (rank : 12)
Query Neighborhood Hits	174	Target Neighborhood Hits	111	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX6_HUMAN
θ value	2.41655e-45 (rank : 41)	NC score	0.964473 (rank : 10)
Query Neighborhood Hits	174	Target Neighborhood Hits	97	Shared Neighborhood Hits	85
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
θ value	2.41655e-45 (rank : 42)	NC score	0.964245 (rank : 11)
Query Neighborhood Hits	174	Target Neighborhood Hits	98	Shared Neighborhood Hits	85
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX56_MOUSE
θ value	1.19932e-44 (rank : 43)	NC score	0.957741 (rank : 31)
Query Neighborhood Hits	174	Target Neighborhood Hits	87	Shared Neighborhood Hits	74
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX52_MOUSE
θ value	1.56636e-44 (rank : 44)	NC score	0.964734 (rank : 9)
Query Neighborhood Hits	174	Target Neighborhood Hits	101	Shared Neighborhood Hits	87
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX46_HUMAN
θ value	3.48949e-44 (rank : 45)	NC score	0.943492 (rank : 51)
Query Neighborhood Hits	174	Target Neighborhood Hits	357	Shared Neighborhood Hits	114
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
θ value	3.48949e-44 (rank : 46)	NC score	0.941439 (rank : 55)
Query Neighborhood Hits	174	Target Neighborhood Hits	358	Shared Neighborhood Hits	117
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX31_HUMAN
θ value	1.01529e-43 (rank : 47)	NC score	0.955012 (rank : 39)
Query Neighborhood Hits	174	Target Neighborhood Hits	132	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX56_HUMAN
θ value	1.32601e-43 (rank : 48)	NC score	0.958056 (rank : 25)
Query Neighborhood Hits	174	Target Neighborhood Hits	77	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DDX43_HUMAN
θ value	1.12253e-42 (rank : 49)	NC score	0.960289 (rank : 19)
Query Neighborhood Hits	174	Target Neighborhood Hits	120	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX55_MOUSE
θ value	8.04462e-41 (rank : 50)	NC score	0.958228 (rank : 24)
Query Neighborhood Hits	174	Target Neighborhood Hits	111	Shared Neighborhood Hits	86
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX55_HUMAN
θ value	3.37985e-39 (rank : 51)	NC score	0.957028 (rank : 36)
Query Neighborhood Hits	174	Target Neighborhood Hits	122	Shared Neighborhood Hits	88
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX20_HUMAN
θ value	9.83387e-39 (rank : 52)	NC score	0.943557 (rank : 50)
Query Neighborhood Hits	174	Target Neighborhood Hits	121	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX25_MOUSE
θ value	1.28434e-38 (rank : 53)	NC score	0.938548 (rank : 57)
Query Neighborhood Hits	174	Target Neighborhood Hits	98	Shared Neighborhood Hits	85
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DD19A_MOUSE
θ value	2.86122e-38 (rank : 54)	NC score	0.937032 (rank : 61)
Query Neighborhood Hits	174	Target Neighborhood Hits	105	Shared Neighborhood Hits	87
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DD19A_HUMAN
θ value	4.88048e-38 (rank : 55)	NC score	0.937415 (rank : 60)
Query Neighborhood Hits	174	Target Neighborhood Hits	107	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DDX20_MOUSE
θ value	6.37413e-38 (rank : 56)	NC score	0.940252 (rank : 56)
Query Neighborhood Hits	174	Target Neighborhood Hits	177	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX21_MOUSE
θ value	1.42001e-37 (rank : 57)	NC score	0.926693 (rank : 66)
Query Neighborhood Hits	174	Target Neighborhood Hits	350	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DD19B_HUMAN
θ value	3.16345e-37 (rank : 58)	NC score	0.936841 (rank : 62)
Query Neighborhood Hits	174	Target Neighborhood Hits	109	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DDX25_HUMAN
θ value	2.05049e-36 (rank : 59)	NC score	0.938342 (rank : 58)
Query Neighborhood Hits	174	Target Neighborhood Hits	93	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX21_HUMAN
θ value	2.67802e-36 (rank : 60)	NC score	0.933779 (rank : 65)
Query Neighborhood Hits	174	Target Neighborhood Hits	308	Shared Neighborhood Hits	103
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX50_HUMAN
θ value	2.67802e-36 (rank : 61)	NC score	0.943228 (rank : 53)
Query Neighborhood Hits	174	Target Neighborhood Hits	132	Shared Neighborhood Hits	90
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_MOUSE
θ value	2.67802e-36 (rank : 62)	NC score	0.943359 (rank : 52)
Query Neighborhood Hits	174	Target Neighborhood Hits	137	Shared Neighborhood Hits	91
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX24_HUMAN
θ value	9.52487e-34 (rank : 63)	NC score	0.934666 (rank : 64)
Query Neighborhood Hits	174	Target Neighborhood Hits	190	Shared Neighborhood Hits	89
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX24_MOUSE
θ value	1.24399e-33 (rank : 64)	NC score	0.937487 (rank : 59)
Query Neighborhood Hits	174	Target Neighborhood Hits	147	Shared Neighborhood Hits	91
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX28_MOUSE
θ value	2.59387e-31 (rank : 65)	NC score	0.951890 (rank : 46)
Query Neighborhood Hits	174	Target Neighborhood Hits	112	Shared Neighborhood Hits	89
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX28_HUMAN
θ value	4.57862e-28 (rank : 66)	NC score	0.947387 (rank : 49)
Query Neighborhood Hits	174	Target Neighborhood Hits	103	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX1_MOUSE
θ value	1.99067e-23 (rank : 67)	NC score	0.884593 (rank : 67)
Query Neighborhood Hits	174	Target Neighborhood Hits	112	Shared Neighborhood Hits	83
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX1_HUMAN
θ value	1.058e-16 (rank : 68)	NC score	0.881460 (rank : 68)
Query Neighborhood Hits	174	Target Neighborhood Hits	110	Shared Neighborhood Hits	83
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

RECQ5_HUMAN
θ value	3.29651e-10 (rank : 69)	NC score	0.483853 (rank : 73)
Query Neighborhood Hits	174	Target Neighborhood Hits	390	Shared Neighborhood Hits	78
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

FANCM_HUMAN
θ value	5.81887e-07 (rank : 70)	NC score	0.457681 (rank : 75)
Query Neighborhood Hits	174	Target Neighborhood Hits	210	Shared Neighborhood Hits	86
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

RECQ1_HUMAN
θ value	1.09739e-05 (rank : 71)	NC score	0.446168 (rank : 78)
Query Neighborhood Hits	174	Target Neighborhood Hits	100	Shared Neighborhood Hits	73
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

FANCM_MOUSE
θ value	1.43324e-05 (rank : 72)	NC score	0.451694 (rank : 76)
Query Neighborhood Hits	174	Target Neighborhood Hits	177	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

LGP2_MOUSE
θ value	1.43324e-05 (rank : 73)	NC score	0.361698 (rank : 82)
Query Neighborhood Hits	174	Target Neighborhood Hits	86	Shared Neighborhood Hits	71
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

RECQ1_MOUSE
θ value	2.44474e-05 (rank : 74)	NC score	0.445637 (rank : 79)
Query Neighborhood Hits	174	Target Neighborhood Hits	95	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ4_MOUSE
θ value	3.19293e-05 (rank : 75)	NC score	0.537676 (rank : 70)
Query Neighborhood Hits	174	Target Neighborhood Hits	206	Shared Neighborhood Hits	83
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

WRN_MOUSE
θ value	0.000121331 (rank : 76)	NC score	0.446614 (rank : 77)
Query Neighborhood Hits	174	Target Neighborhood Hits	295	Shared Neighborhood Hits	90
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

DICER_MOUSE
θ value	0.00020696 (rank : 77)	NC score	0.421117 (rank : 81)
Query Neighborhood Hits	174	Target Neighborhood Hits	140	Shared Neighborhood Hits	84
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

WRN_HUMAN
θ value	0.000270298 (rank : 78)	NC score	0.477661 (rank : 74)
Query Neighborhood Hits	174	Target Neighborhood Hits	132	Shared Neighborhood Hits	84
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

DICER_HUMAN
θ value	0.00035302 (rank : 79)	NC score	0.421751 (rank : 80)
Query Neighborhood Hits	174	Target Neighborhood Hits	126	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

RECQ4_HUMAN
θ value	0.00035302 (rank : 80)	NC score	0.555652 (rank : 69)
Query Neighborhood Hits	174	Target Neighborhood Hits	177	Shared Neighborhood Hits	85
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

LGP2_HUMAN
θ value	0.000602161 (rank : 81)	NC score	0.347476 (rank : 84)
Query Neighborhood Hits	174	Target Neighborhood Hits	94	Shared Neighborhood Hits	72
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

CP250_HUMAN
θ value	0.00175202 (rank : 82)	NC score	0.018035 (rank : 124)
Query Neighborhood Hits	174	Target Neighborhood Hits	1805	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

IFIH1_MOUSE
θ value	0.00228821 (rank : 83)	NC score	0.337886 (rank : 85)
Query Neighborhood Hits	174	Target Neighborhood Hits	126	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

BLM_MOUSE
θ value	0.00869519 (rank : 84)	NC score	0.498768 (rank : 71)
Query Neighborhood Hits	174	Target Neighborhood Hits	108	Shared Neighborhood Hits	72
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

IFIH1_HUMAN
θ value	0.00869519 (rank : 85)	NC score	0.351441 (rank : 83)
Query Neighborhood Hits	174	Target Neighborhood Hits	96	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

TPR_HUMAN
θ value	0.00869519 (rank : 86)	NC score	0.018431 (rank : 121)
Query Neighborhood Hits	174	Target Neighborhood Hits	1921	Shared Neighborhood Hits	63
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

BLM_HUMAN
θ value	0.0148317 (rank : 87)	NC score	0.484093 (rank : 72)
Query Neighborhood Hits	174	Target Neighborhood Hits	148	Shared Neighborhood Hits	76
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

GOGA4_HUMAN
θ value	0.0736092 (rank : 88)	NC score	0.020777 (rank : 114)
Query Neighborhood Hits	174	Target Neighborhood Hits	2034	Shared Neighborhood Hits	70
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

MY18A_MOUSE
θ value	0.0736092 (rank : 89)	NC score	0.019733 (rank : 115)
Query Neighborhood Hits	174	Target Neighborhood Hits	1989	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

IWS1_HUMAN
θ value	0.125558 (rank : 90)	NC score	0.030051 (rank : 105)
Query Neighborhood Hits	174	Target Neighborhood Hits	1241	Shared Neighborhood Hits	51
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

OVGP1_HUMAN
θ value	0.163984 (rank : 91)	NC score	0.014950 (rank : 138)
Query Neighborhood Hits	174	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q12889, Q15841	Gene names	OVGP1, MUC9, OGP
Domain Architecture
Description	Oviduct-specific glycoprotein precursor (Oviductal glycoprotein) (Oviductin) (Estrogen-dependent oviduct protein) (Mucin 9).

CCD41_MOUSE
θ value	0.21417 (rank : 92)	NC score	0.021043 (rank : 112)
Query Neighborhood Hits	174	Target Neighborhood Hits	1399	Shared Neighborhood Hits	57
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

GOGB1_HUMAN
θ value	0.21417 (rank : 93)	NC score	0.020810 (rank : 113)
Query Neighborhood Hits	174	Target Neighborhood Hits	2297	Shared Neighborhood Hits	68
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

ISY1_MOUSE
θ value	0.21417 (rank : 94)	NC score	0.035594 (rank : 100)
Query Neighborhood Hits	174	Target Neighborhood Hits	35	Shared Neighborhood Hits	7
SwissProt Accessions	Q69ZQ2, Q8VDX4, Q9D3E2	Gene names	Kiaa1160
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor ISY1 homolog.

CJ118_MOUSE
θ value	0.279714 (rank : 95)	NC score	0.017603 (rank : 128)
Query Neighborhood Hits	174	Target Neighborhood Hits	1132	Shared Neighborhood Hits	49
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CT2NL_HUMAN
θ value	0.279714 (rank : 96)	NC score	0.032260 (rank : 103)
Query Neighborhood Hits	174	Target Neighborhood Hits	1059	Shared Neighborhood Hits	51
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

ISY1_HUMAN
θ value	0.279714 (rank : 97)	NC score	0.034308 (rank : 102)
Query Neighborhood Hits	174	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULR0, Q96IL2, Q9BT05	Gene names	KIAA1160
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor ISY1 homolog.

IWS1_MOUSE
θ value	0.279714 (rank : 98)	NC score	0.029424 (rank : 107)
Query Neighborhood Hits	174	Target Neighborhood Hits	1258	Shared Neighborhood Hits	45
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MYH9_MOUSE
θ value	0.279714 (rank : 99)	NC score	0.017172 (rank : 130)
Query Neighborhood Hits	174	Target Neighborhood Hits	1829	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

AZI1_HUMAN
θ value	0.365318 (rank : 100)	NC score	0.018187 (rank : 122)
Query Neighborhood Hits	174	Target Neighborhood Hits	1000	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

CHD3_HUMAN
θ value	0.365318 (rank : 101)	NC score	0.039734 (rank : 96)
Query Neighborhood Hits	174	Target Neighborhood Hits	397	Shared Neighborhood Hits	35
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

XRCC4_HUMAN
θ value	0.365318 (rank : 102)	NC score	0.017957 (rank : 126)
Query Neighborhood Hits	174	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	Q13426, Q9BS72, Q9UP94	Gene names	XRCC4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

CT2NL_MOUSE
θ value	0.47712 (rank : 103)	NC score	0.029377 (rank : 108)
Query Neighborhood Hits	174	Target Neighborhood Hits	902	Shared Neighborhood Hits	47
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

MY18A_HUMAN
θ value	0.47712 (rank : 104)	NC score	0.019001 (rank : 118)
Query Neighborhood Hits	174	Target Neighborhood Hits	1929	Shared Neighborhood Hits	74
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH9_HUMAN
θ value	0.47712 (rank : 105)	NC score	0.015554 (rank : 136)
Query Neighborhood Hits	174	Target Neighborhood Hits	1762	Shared Neighborhood Hits	60
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

NIN_HUMAN
θ value	0.62314 (rank : 106)	NC score	0.014626 (rank : 140)
Query Neighborhood Hits	174	Target Neighborhood Hits	1416	Shared Neighborhood Hits	52
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

TCAL3_HUMAN
θ value	0.62314 (rank : 107)	NC score	0.023606 (rank : 111)
Query Neighborhood Hits	174	Target Neighborhood Hits	274	Shared Neighborhood Hits	15
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

CEP63_HUMAN
θ value	0.813845 (rank : 108)	NC score	0.013611 (rank : 145)
Query Neighborhood Hits	174	Target Neighborhood Hits	1005	Shared Neighborhood Hits	44
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CN044_HUMAN
θ value	0.813845 (rank : 109)	NC score	0.017187 (rank : 129)
Query Neighborhood Hits	174	Target Neighborhood Hits	227	Shared Neighborhood Hits	21
SwissProt Accessions	Q96MY7	Gene names	C14orf44
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf44.

IFIT3_HUMAN
θ value	0.813845 (rank : 110)	NC score	0.008299 (rank : 165)
Query Neighborhood Hits	174	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	O14879, Q99634, Q9BSK7	Gene names	IFIT3, IFI60, IFIT4
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (IFIT-4) (Interferon-induced 60 kDa protein) (IFI-60K) (ISG-60) (CIG49) (Retinoic acid-induced gene G protein) (RIG-G).

HDAC9_MOUSE
θ value	1.06291 (rank : 111)	NC score	0.012136 (rank : 153)
Query Neighborhood Hits	174	Target Neighborhood Hits	186	Shared Neighborhood Hits	17
SwissProt Accessions	Q99N13, Q9EPT2	Gene names	Hdac9, Hdac7b, Hdrp, Mitr
Domain Architecture	No domain graphic available
Description	Histone deacetylase 9 (HD9) (HD7B) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR).

LRRF1_HUMAN
θ value	1.06291 (rank : 112)	NC score	0.017851 (rank : 127)
Query Neighborhood Hits	174	Target Neighborhood Hits	625	Shared Neighborhood Hits	44
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

LEO1_HUMAN
θ value	1.38821 (rank : 113)	NC score	0.036591 (rank : 99)
Query Neighborhood Hits	174	Target Neighborhood Hits	958	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

PHF20_MOUSE
θ value	1.38821 (rank : 114)	NC score	0.039619 (rank : 97)
Query Neighborhood Hits	174	Target Neighborhood Hits	513	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

TPM4_MOUSE
θ value	1.38821 (rank : 115)	NC score	0.014176 (rank : 143)
Query Neighborhood Hits	174	Target Neighborhood Hits	703	Shared Neighborhood Hits	44
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

EPN4_MOUSE
θ value	1.81305 (rank : 116)	NC score	0.018648 (rank : 120)
Query Neighborhood Hits	174	Target Neighborhood Hits	58	Shared Neighborhood Hits	8
SwissProt Accessions	Q99KN9, Q8CFH4	Gene names	Clint1, Enth, Epn4, Epnr, Kiaa0171
Domain Architecture
Description	Clathrin interactor 1 (Epsin-4) (Epsin-related protein) (EpsinR) (Enthoprotin).

LEO1_MOUSE
θ value	1.81305 (rank : 117)	NC score	0.037044 (rank : 98)
Query Neighborhood Hits	174	Target Neighborhood Hits	946	Shared Neighborhood Hits	51
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

TCAL5_HUMAN
θ value	1.81305 (rank : 118)	NC score	0.024202 (rank : 110)
Query Neighborhood Hits	174	Target Neighborhood Hits	806	Shared Neighborhood Hits	34
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

CA051_MOUSE
θ value	2.36792 (rank : 119)	NC score	0.016100 (rank : 133)
Query Neighborhood Hits	174	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q3TQ03, Q3U1B8	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf51 homolog.

CDC37_HUMAN
θ value	2.36792 (rank : 120)	NC score	0.019511 (rank : 116)
Query Neighborhood Hits	174	Target Neighborhood Hits	506	Shared Neighborhood Hits	33
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

CYBP_HUMAN
θ value	2.36792 (rank : 121)	NC score	0.024435 (rank : 109)
Query Neighborhood Hits	174	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HB71, O60666	Gene names	CACYBP, S100A6BP, SIP
Domain Architecture
Description	Calcyclin-binding protein (CacyBP) (hCacyBP) (Siah-interacting protein) (S100A6-binding protein).

PHF14_HUMAN
θ value	2.36792 (rank : 122)	NC score	0.010831 (rank : 159)
Query Neighborhood Hits	174	Target Neighborhood Hits	447	Shared Neighborhood Hits	40
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

CHD4_HUMAN
θ value	3.0926 (rank : 123)	NC score	0.045624 (rank : 94)
Query Neighborhood Hits	174	Target Neighborhood Hits	365	Shared Neighborhood Hits	38
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	3.0926 (rank : 124)	NC score	0.045440 (rank : 95)
Query Neighborhood Hits	174	Target Neighborhood Hits	408	Shared Neighborhood Hits	42
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD5_HUMAN
θ value	3.0926 (rank : 125)	NC score	0.034644 (rank : 101)
Query Neighborhood Hits	174	Target Neighborhood Hits	349	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

IRX2_HUMAN
θ value	3.0926 (rank : 126)	NC score	0.002444 (rank : 177)
Query Neighborhood Hits	174	Target Neighborhood Hits	358	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BZI1, Q7Z2I7	Gene names	IRX2, IRXA2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-2 (Iroquois homeobox protein 2) (Homeodomain protein IRXA2).

MPP8_HUMAN
θ value	3.0926 (rank : 127)	NC score	0.030000 (rank : 106)
Query Neighborhood Hits	174	Target Neighborhood Hits	948	Shared Neighborhood Hits	56
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

MYRIP_HUMAN
θ value	3.0926 (rank : 128)	NC score	0.011029 (rank : 156)
Query Neighborhood Hits	174	Target Neighborhood Hits	269	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

PARP1_MOUSE
θ value	3.0926 (rank : 129)	NC score	0.005717 (rank : 169)
Query Neighborhood Hits	174	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

UBE3C_HUMAN
θ value	3.0926 (rank : 130)	NC score	0.005074 (rank : 171)
Query Neighborhood Hits	174	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

ADA30_HUMAN
θ value	4.03905 (rank : 131)	NC score	0.005412 (rank : 170)
Query Neighborhood Hits	174	Target Neighborhood Hits	391	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ALO17_HUMAN
θ value	4.03905 (rank : 132)	NC score	0.007959 (rank : 166)
Query Neighborhood Hits	174	Target Neighborhood Hits	317	Shared Neighborhood Hits	15
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

BCAR1_HUMAN
θ value	4.03905 (rank : 133)	NC score	0.002120 (rank : 178)
Query Neighborhood Hits	174	Target Neighborhood Hits	554	Shared Neighborhood Hits	4
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

EPN4_HUMAN
θ value	4.03905 (rank : 134)	NC score	0.016013 (rank : 135)
Query Neighborhood Hits	174	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q14677, Q8NAF1, Q96E05	Gene names	CLINT1, ENTH, EPN4, EPNR, KIAA0171
Domain Architecture
Description	Clathrin interactor 1 (Epsin-4) (Epsin-related protein) (EpsinR) (Enthoprotin) (Clathrin-interacting protein localized in the trans- Golgi region) (Clint).

HMGN1_HUMAN
θ value	4.03905 (rank : 135)	NC score	0.013606 (rank : 146)
Query Neighborhood Hits	174	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	P05114, Q3KQR8	Gene names	HMGN1, HMG14
Domain Architecture	No domain graphic available
Description	Nonhistone chromosomal protein HMG-14 (High-mobility group nucleosome- binding domain-containing protein 1).

IF3A_HUMAN
θ value	4.03905 (rank : 136)	NC score	0.018772 (rank : 119)
Query Neighborhood Hits	174	Target Neighborhood Hits	875	Shared Neighborhood Hits	52
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

KI21A_HUMAN
θ value	4.03905 (rank : 137)	NC score	0.010675 (rank : 160)
Query Neighborhood Hits	174	Target Neighborhood Hits	1543	Shared Neighborhood Hits	61
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

MYRIP_MOUSE
θ value	4.03905 (rank : 138)	NC score	0.013590 (rank : 147)
Query Neighborhood Hits	174	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

NDUB5_HUMAN
θ value	4.03905 (rank : 139)	NC score	0.009968 (rank : 163)
Query Neighborhood Hits	174	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	O43674	Gene names	NDUFB5
Domain Architecture	No domain graphic available
Description	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial precursor (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase SGDH subunit) (Complex I-SGDH) (CI-SGDH).

RN169_HUMAN
θ value	4.03905 (rank : 140)	NC score	0.010889 (rank : 158)
Query Neighborhood Hits	174	Target Neighborhood Hits	203	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

RRBP1_HUMAN
θ value	4.03905 (rank : 141)	NC score	0.017991 (rank : 125)
Query Neighborhood Hits	174	Target Neighborhood Hits	1306	Shared Neighborhood Hits	60
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

CK5P2_HUMAN
θ value	5.27518 (rank : 142)	NC score	0.019206 (rank : 117)
Query Neighborhood Hits	174	Target Neighborhood Hits	1433	Shared Neighborhood Hits	58
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CKAP4_HUMAN
θ value	5.27518 (rank : 143)	NC score	0.014324 (rank : 142)
Query Neighborhood Hits	174	Target Neighborhood Hits	592	Shared Neighborhood Hits	37
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CMGA_HUMAN
θ value	5.27518 (rank : 144)	NC score	0.031333 (rank : 104)
Query Neighborhood Hits	174	Target Neighborhood Hits	238	Shared Neighborhood Hits	24
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

DDX58_MOUSE
θ value	5.27518 (rank : 145)	NC score	0.222627 (rank : 86)
Query Neighborhood Hits	174	Target Neighborhood Hits	99	Shared Neighborhood Hits	62
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

HMMR_MOUSE
θ value	5.27518 (rank : 146)	NC score	0.015056 (rank : 137)
Query Neighborhood Hits	174	Target Neighborhood Hits	1178	Shared Neighborhood Hits	55
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

IF3A_MOUSE
θ value	5.27518 (rank : 147)	NC score	0.018126 (rank : 123)
Query Neighborhood Hits	174	Target Neighborhood Hits	871	Shared Neighborhood Hits	52
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

MYH2_HUMAN
θ value	5.27518 (rank : 148)	NC score	0.012516 (rank : 152)
Query Neighborhood Hits	174	Target Neighborhood Hits	1491	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

RGNEF_MOUSE
θ value	5.27518 (rank : 149)	NC score	0.005841 (rank : 168)
Query Neighborhood Hits	174	Target Neighborhood Hits	641	Shared Neighborhood Hits	38
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

UBE3C_MOUSE
θ value	5.27518 (rank : 150)	NC score	0.004616 (rank : 172)
Query Neighborhood Hits	174	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

C1TC_HUMAN
θ value	6.88961 (rank : 151)	NC score	0.004510 (rank : 173)
Query Neighborhood Hits	174	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	P11586, Q86VC9, Q9BVP5	Gene names	MTHFD1, MTHFC, MTHFD
Domain Architecture
Description	C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF synthase) [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)].

CING_HUMAN
θ value	6.88961 (rank : 152)	NC score	0.014559 (rank : 141)
Query Neighborhood Hits	174	Target Neighborhood Hits	1275	Shared Neighborhood Hits	50
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CP135_HUMAN
θ value	6.88961 (rank : 153)	NC score	0.011460 (rank : 155)
Query Neighborhood Hits	174	Target Neighborhood Hits	1290	Shared Neighborhood Hits	49
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

ERC2_HUMAN
θ value	6.88961 (rank : 154)	NC score	0.012637 (rank : 150)
Query Neighborhood Hits	174	Target Neighborhood Hits	1156	Shared Neighborhood Hits	52
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ERC2_MOUSE
θ value	6.88961 (rank : 155)	NC score	0.012791 (rank : 149)
Query Neighborhood Hits	174	Target Neighborhood Hits	1166	Shared Neighborhood Hits	52
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

MTSS1_MOUSE
θ value	6.88961 (rank : 156)	NC score	0.002574 (rank : 176)
Query Neighborhood Hits	174	Target Neighborhood Hits	592	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

NOTC2_MOUSE
θ value	6.88961 (rank : 157)	NC score	-0.005626 (rank : 180)
Query Neighborhood Hits	174	Target Neighborhood Hits	1069	Shared Neighborhood Hits	7
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PEG3_MOUSE
θ value	6.88961 (rank : 158)	NC score	-0.006061 (rank : 181)
Query Neighborhood Hits	174	Target Neighborhood Hits	1101	Shared Neighborhood Hits	16
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

SETD2_HUMAN
θ value	6.88961 (rank : 159)	NC score	0.009529 (rank : 164)
Query Neighborhood Hits	174	Target Neighborhood Hits	412	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SETX_HUMAN
θ value	6.88961 (rank : 160)	NC score	0.013467 (rank : 148)
Query Neighborhood Hits	174	Target Neighborhood Hits	368	Shared Neighborhood Hits	24
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

SM1L2_MOUSE
θ value	6.88961 (rank : 161)	NC score	0.016053 (rank : 134)
Query Neighborhood Hits	174	Target Neighborhood Hits	918	Shared Neighborhood Hits	48
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

TTC1_HUMAN
θ value	6.88961 (rank : 162)	NC score	0.004334 (rank : 174)
Query Neighborhood Hits	174	Target Neighborhood Hits	417	Shared Neighborhood Hits	20
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

TUFT1_MOUSE
θ value	6.88961 (rank : 163)	NC score	0.014845 (rank : 139)
Query Neighborhood Hits	174	Target Neighborhood Hits	732	Shared Neighborhood Hits	43
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

AKAP9_HUMAN
θ value	8.99809 (rank : 164)	NC score	0.010004 (rank : 162)
Query Neighborhood Hits	174	Target Neighborhood Hits	1710	Shared Neighborhood Hits	55
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

ANR26_MOUSE
θ value	8.99809 (rank : 165)	NC score	0.006729 (rank : 167)
Query Neighborhood Hits	174	Target Neighborhood Hits	1554	Shared Neighborhood Hits	53
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CCD21_HUMAN
θ value	8.99809 (rank : 166)	NC score	0.014137 (rank : 144)
Query Neighborhood Hits	174	Target Neighborhood Hits	1228	Shared Neighborhood Hits	57
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CKAP4_MOUSE
θ value	8.99809 (rank : 167)	NC score	0.012617 (rank : 151)
Query Neighborhood Hits	174	Target Neighborhood Hits	596	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

DYH5_MOUSE
θ value	8.99809 (rank : 168)	NC score	0.010631 (rank : 161)
Query Neighborhood Hits	174	Target Neighborhood Hits	286	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VHE6, Q8BWG1	Gene names	Dnah5, Dnahc5
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (Mdnah5).

HERC2_HUMAN
θ value	8.99809 (rank : 169)	NC score	0.003215 (rank : 175)
Query Neighborhood Hits	174	Target Neighborhood Hits	163	Shared Neighborhood Hits	9
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HIP1R_MOUSE
θ value	8.99809 (rank : 170)	NC score	0.010948 (rank : 157)
Query Neighborhood Hits	174	Target Neighborhood Hits	959	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

K2C5_MOUSE
θ value	8.99809 (rank : 171)	NC score	0.002078 (rank : 179)
Query Neighborhood Hits	174	Target Neighborhood Hits	505	Shared Neighborhood Hits	34
SwissProt Accessions	Q922U2, Q920F2	Gene names	Krt5, Krt2-5
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5).

SMC3_HUMAN
θ value	8.99809 (rank : 172)	NC score	0.016210 (rank : 132)
Query Neighborhood Hits	174	Target Neighborhood Hits	1186	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	8.99809 (rank : 173)	NC score	0.016316 (rank : 131)
Query Neighborhood Hits	174	Target Neighborhood Hits	1187	Shared Neighborhood Hits	55
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

ZWINT_HUMAN
θ value	8.99809 (rank : 174)	NC score	0.011535 (rank : 154)
Query Neighborhood Hits	174	Target Neighborhood Hits	333	Shared Neighborhood Hits	30
SwissProt Accessions	O95229, Q9BWD0	Gene names	ZWINT
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

CC026_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.157893 (rank : 88)
Query Neighborhood Hits	174	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

CC026_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.126765 (rank : 90)
Query Neighborhood Hits	174	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

DDX58_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.186084 (rank : 87)
Query Neighborhood Hits	174	Target Neighborhood Hits	105	Shared Neighborhood Hits	60
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

HELC1_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.100098 (rank : 91)
Query Neighborhood Hits	174	Target Neighborhood Hits	71	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

SMAL1_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.074415 (rank : 92)
Query Neighborhood Hits	174	Target Neighborhood Hits	174	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

SMAL1_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.050745 (rank : 93)
Query Neighborhood Hits	174	Target Neighborhood Hits	157	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

U520_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.132790 (rank : 89)
Query Neighborhood Hits	174	Target Neighborhood Hits	88	Shared Neighborhood Hits	47
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

Hits sorted by NC score

DDX27_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	174	Target Neighborhood Hits	174	Shared Neighborhood Hits	174
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_HUMAN
NC score	0.995483 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	174	Target Neighborhood Hits	197	Shared Neighborhood Hits	128
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX47_MOUSE
NC score	0.978946 (rank : 3)	θ value	6.31527e-70 (rank : 4)
Query Neighborhood Hits	174	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_HUMAN
NC score	0.978797 (rank : 4)	θ value	1.7756e-72 (rank : 3)
Query Neighborhood Hits	174	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX49_MOUSE
NC score	0.976679 (rank : 5)	θ value	1.36269e-64 (rank : 6)
Query Neighborhood Hits	174	Target Neighborhood Hits	119	Shared Neighborhood Hits	87
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX49_HUMAN
NC score	0.973045 (rank : 6)	θ value	1.45591e-66 (rank : 5)
Query Neighborhood Hits	174	Target Neighborhood Hits	223	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX54_MOUSE
NC score	0.965443 (rank : 7)	θ value	4.53632e-60 (rank : 7)
Query Neighborhood Hits	174	Target Neighborhood Hits	124	Shared Neighborhood Hits	85
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX52_HUMAN
NC score	0.965118 (rank : 8)	θ value	2.58187e-47 (rank : 38)
Query Neighborhood Hits	174	Target Neighborhood Hits	107	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX52_MOUSE
NC score	0.964734 (rank : 9)	θ value	1.56636e-44 (rank : 44)
Query Neighborhood Hits	174	Target Neighborhood Hits	101	Shared Neighborhood Hits	87
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX6_HUMAN
NC score	0.964473 (rank : 10)	θ value	2.41655e-45 (rank : 41)
Query Neighborhood Hits	174	Target Neighborhood Hits	97	Shared Neighborhood Hits	85
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
NC score	0.964245 (rank : 11)	θ value	2.41655e-45 (rank : 42)
Query Neighborhood Hits	174	Target Neighborhood Hits	98	Shared Neighborhood Hits	85
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX41_HUMAN
NC score	0.963414 (rank : 12)	θ value	3.72821e-46 (rank : 40)
Query Neighborhood Hits	174	Target Neighborhood Hits	111	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
NC score	0.963113 (rank : 13)	θ value	2.85459e-46 (rank : 39)
Query Neighborhood Hits	174	Target Neighborhood Hits	115	Shared Neighborhood Hits	90
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX18_MOUSE
NC score	0.962077 (rank : 14)	θ value	3.974e-56 (rank : 8)
Query Neighborhood Hits	174	Target Neighborhood Hits	115	Shared Neighborhood Hits	79
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX54_HUMAN
NC score	0.961595 (rank : 15)	θ value	5.19021e-56 (rank : 9)
Query Neighborhood Hits	174	Target Neighborhood Hits	170	Shared Neighborhood Hits	87
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX4_MOUSE
NC score	0.961232 (rank : 16)	θ value	1.32293e-51 (rank : 19)
Query Neighborhood Hits	174	Target Neighborhood Hits	100	Shared Neighborhood Hits	86
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX4_HUMAN
NC score	0.960567 (rank : 17)	θ value	9.16162e-53 (rank : 17)
Query Neighborhood Hits	174	Target Neighborhood Hits	123	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX18_HUMAN
NC score	0.960382 (rank : 18)	θ value	7.75577e-52 (rank : 18)
Query Neighborhood Hits	174	Target Neighborhood Hits	124	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX43_HUMAN
NC score	0.960289 (rank : 19)	θ value	1.12253e-42 (rank : 49)
Query Neighborhood Hits	174	Target Neighborhood Hits	120	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX48_HUMAN
NC score	0.960188 (rank : 20)	θ value	1.61718e-49 (rank : 25)
Query Neighborhood Hits	174	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
NC score	0.960009 (rank : 21)	θ value	2.1121e-49 (rank : 26)
Query Neighborhood Hits	174	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX39_HUMAN
NC score	0.959462 (rank : 22)	θ value	9.48078e-50 (rank : 24)
Query Neighborhood Hits	174	Target Neighborhood Hits	94	Shared Neighborhood Hits	86
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX39_MOUSE
NC score	0.958638 (rank : 23)	θ value	1.36902e-48 (rank : 28)
Query Neighborhood Hits	174	Target Neighborhood Hits	97	Shared Neighborhood Hits	85
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX55_MOUSE
NC score	0.958228 (rank : 24)	θ value	8.04462e-41 (rank : 50)
Query Neighborhood Hits	174	Target Neighborhood Hits	111	Shared Neighborhood Hits	86
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX56_HUMAN
NC score	0.958056 (rank : 25)	θ value	1.32601e-43 (rank : 48)
Query Neighborhood Hits	174	Target Neighborhood Hits	77	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

IF4A1_HUMAN
NC score	0.957887 (rank : 26)	θ value	3.98324e-48 (rank : 32)
Query Neighborhood Hits	174	Target Neighborhood Hits	106	Shared Neighborhood Hits	86
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
NC score	0.957887 (rank : 27)	θ value	3.98324e-48 (rank : 33)
Query Neighborhood Hits	174	Target Neighborhood Hits	106	Shared Neighborhood Hits	86
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

DDX10_HUMAN
NC score	0.957863 (rank : 28)	θ value	5.73848e-55 (rank : 10)
Query Neighborhood Hits	174	Target Neighborhood Hits	210	Shared Neighborhood Hits	98
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

UAP56_HUMAN
NC score	0.957803 (rank : 29)	θ value	7.25919e-50 (rank : 23)
Query Neighborhood Hits	174	Target Neighborhood Hits	96	Shared Neighborhood Hits	85
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
NC score	0.957781 (rank : 30)	θ value	2.49495e-50 (rank : 21)
Query Neighborhood Hits	174	Target Neighborhood Hits	96	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX56_MOUSE
NC score	0.957741 (rank : 31)	θ value	1.19932e-44 (rank : 43)
Query Neighborhood Hits	174	Target Neighborhood Hits	87	Shared Neighborhood Hits	74
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

IF4A2_HUMAN
NC score	0.957627 (rank : 32)	θ value	6.7944e-48 (rank : 34)
Query Neighborhood Hits	174	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
NC score	0.957627 (rank : 33)	θ value	6.7944e-48 (rank : 35)
Query Neighborhood Hits	174	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX17_MOUSE
NC score	0.957472 (rank : 34)	θ value	1.788e-48 (rank : 30)
Query Neighborhood Hits	174	Target Neighborhood Hits	105	Shared Neighborhood Hits	87
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX17_HUMAN
NC score	0.957335 (rank : 35)	θ value	1.788e-48 (rank : 29)
Query Neighborhood Hits	174	Target Neighborhood Hits	104	Shared Neighborhood Hits	87
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX55_HUMAN
NC score	0.957028 (rank : 36)	θ value	3.37985e-39 (rank : 51)
Query Neighborhood Hits	174	Target Neighborhood Hits	122	Shared Neighborhood Hits	88
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX10_MOUSE
NC score	0.956570 (rank : 37)	θ value	3.1488e-53 (rank : 16)
Query Neighborhood Hits	174	Target Neighborhood Hits	233	Shared Neighborhood Hits	95
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX53_HUMAN
NC score	0.955971 (rank : 38)	θ value	5.55816e-50 (rank : 22)
Query Neighborhood Hits	174	Target Neighborhood Hits	124	Shared Neighborhood Hits	82
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX31_HUMAN
NC score	0.955012 (rank : 39)	θ value	1.01529e-43 (rank : 47)
Query Neighborhood Hits	174	Target Neighborhood Hits	132	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

PL10_MOUSE
NC score	0.953283 (rank : 40)	θ value	9.78833e-55 (rank : 11)
Query Neighborhood Hits	174	Target Neighborhood Hits	120	Shared Neighborhood Hits	90
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3X_HUMAN
NC score	0.953157 (rank : 41)	θ value	1.2784e-54 (rank : 12)
Query Neighborhood Hits	174	Target Neighborhood Hits	122	Shared Neighborhood Hits	91
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX5_HUMAN
NC score	0.952986 (rank : 42)	θ value	3.04986e-48 (rank : 31)
Query Neighborhood Hits	174	Target Neighborhood Hits	102	Shared Neighborhood Hits	87
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
NC score	0.952848 (rank : 43)	θ value	8.87376e-48 (rank : 36)
Query Neighborhood Hits	174	Target Neighborhood Hits	101	Shared Neighborhood Hits	87
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX3Y_MOUSE
NC score	0.952714 (rank : 44)	θ value	5.02714e-51 (rank : 20)
Query Neighborhood Hits	174	Target Neighborhood Hits	126	Shared Neighborhood Hits	90
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX3X_MOUSE
NC score	0.952540 (rank : 45)	θ value	1.41344e-53 (rank : 14)
Query Neighborhood Hits	174	Target Neighborhood Hits	117	Shared Neighborhood Hits	90
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX28_MOUSE
NC score	0.951890 (rank : 46)	θ value	2.59387e-31 (rank : 65)
Query Neighborhood Hits	174	Target Neighborhood Hits	112	Shared Neighborhood Hits	89
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX51_MOUSE
NC score	0.951820 (rank : 47)	θ value	8.02596e-49 (rank : 27)
Query Neighborhood Hits	174	Target Neighborhood Hits	130	Shared Neighborhood Hits	87
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX3Y_HUMAN
NC score	0.951618 (rank : 48)	θ value	1.84601e-53 (rank : 15)
Query Neighborhood Hits	174	Target Neighborhood Hits	121	Shared Neighborhood Hits	90
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX28_HUMAN
NC score	0.947387 (rank : 49)	θ value	4.57862e-28 (rank : 66)
Query Neighborhood Hits	174	Target Neighborhood Hits	103	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX20_HUMAN
NC score	0.943557 (rank : 50)	θ value	9.83387e-39 (rank : 52)
Query Neighborhood Hits	174	Target Neighborhood Hits	121	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX46_HUMAN
NC score	0.943492 (rank : 51)	θ value	3.48949e-44 (rank : 45)
Query Neighborhood Hits	174	Target Neighborhood Hits	357	Shared Neighborhood Hits	114
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX50_MOUSE
NC score	0.943359 (rank : 52)	θ value	2.67802e-36 (rank : 62)
Query Neighborhood Hits	174	Target Neighborhood Hits	137	Shared Neighborhood Hits	91
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_HUMAN
NC score	0.943228 (rank : 53)	θ value	2.67802e-36 (rank : 61)
Query Neighborhood Hits	174	Target Neighborhood Hits	132	Shared Neighborhood Hits	90
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX23_HUMAN
NC score	0.942058 (rank : 54)	θ value	8.28633e-54 (rank : 13)
Query Neighborhood Hits	174	Target Neighborhood Hits	486	Shared Neighborhood Hits	127
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX46_MOUSE
NC score	0.941439 (rank : 55)	θ value	3.48949e-44 (rank : 46)
Query Neighborhood Hits	174	Target Neighborhood Hits	358	Shared Neighborhood Hits	117
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX20_MOUSE
NC score	0.940252 (rank : 56)	θ value	6.37413e-38 (rank : 56)
Query Neighborhood Hits	174	Target Neighborhood Hits	177	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX25_MOUSE
NC score	0.938548 (rank : 57)	θ value	1.28434e-38 (rank : 53)
Query Neighborhood Hits	174	Target Neighborhood Hits	98	Shared Neighborhood Hits	85
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX25_HUMAN
NC score	0.938342 (rank : 58)	θ value	2.05049e-36 (rank : 59)
Query Neighborhood Hits	174	Target Neighborhood Hits	93	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX24_MOUSE
NC score	0.937487 (rank : 59)	θ value	1.24399e-33 (rank : 64)
Query Neighborhood Hits	174	Target Neighborhood Hits	147	Shared Neighborhood Hits	91
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DD19A_HUMAN
NC score	0.937415 (rank : 60)	θ value	4.88048e-38 (rank : 55)
Query Neighborhood Hits	174	Target Neighborhood Hits	107	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19A_MOUSE
NC score	0.937032 (rank : 61)	θ value	2.86122e-38 (rank : 54)
Query Neighborhood Hits	174	Target Neighborhood Hits	105	Shared Neighborhood Hits	87
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DD19B_HUMAN
NC score	0.936841 (rank : 62)	θ value	3.16345e-37 (rank : 58)
Query Neighborhood Hits	174	Target Neighborhood Hits	109	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DDX51_HUMAN
NC score	0.936834 (rank : 63)	θ value	2.58187e-47 (rank : 37)
Query Neighborhood Hits	174	Target Neighborhood Hits	332	Shared Neighborhood Hits	90
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX24_HUMAN
NC score	0.934666 (rank : 64)	θ value	9.52487e-34 (rank : 63)
Query Neighborhood Hits	174	Target Neighborhood Hits	190	Shared Neighborhood Hits	89
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX21_HUMAN
NC score	0.933779 (rank : 65)	θ value	2.67802e-36 (rank : 60)
Query Neighborhood Hits	174	Target Neighborhood Hits	308	Shared Neighborhood Hits	103
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX21_MOUSE
NC score	0.926693 (rank : 66)	θ value	1.42001e-37 (rank : 57)
Query Neighborhood Hits	174	Target Neighborhood Hits	350	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX1_MOUSE
NC score	0.884593 (rank : 67)	θ value	1.99067e-23 (rank : 67)
Query Neighborhood Hits	174	Target Neighborhood Hits	112	Shared Neighborhood Hits	83
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX1_HUMAN
NC score	0.881460 (rank : 68)	θ value	1.058e-16 (rank : 68)
Query Neighborhood Hits	174	Target Neighborhood Hits	110	Shared Neighborhood Hits	83
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

RECQ4_HUMAN
NC score	0.555652 (rank : 69)	θ value	0.00035302 (rank : 80)
Query Neighborhood Hits	174	Target Neighborhood Hits	177	Shared Neighborhood Hits	85
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RECQ4_MOUSE
NC score	0.537676 (rank : 70)	θ value	3.19293e-05 (rank : 75)
Query Neighborhood Hits	174	Target Neighborhood Hits	206	Shared Neighborhood Hits	83
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

BLM_MOUSE
NC score	0.498768 (rank : 71)	θ value	0.00869519 (rank : 84)
Query Neighborhood Hits	174	Target Neighborhood Hits	108	Shared Neighborhood Hits	72
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

BLM_HUMAN
NC score	0.484093 (rank : 72)	θ value	0.0148317 (rank : 87)
Query Neighborhood Hits	174	Target Neighborhood Hits	148	Shared Neighborhood Hits	76
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

RECQ5_HUMAN
NC score	0.483853 (rank : 73)	θ value	3.29651e-10 (rank : 69)
Query Neighborhood Hits	174	Target Neighborhood Hits	390	Shared Neighborhood Hits	78
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

WRN_HUMAN
NC score	0.477661 (rank : 74)	θ value	0.000270298 (rank : 78)
Query Neighborhood Hits	174	Target Neighborhood Hits	132	Shared Neighborhood Hits	84
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

FANCM_HUMAN
NC score	0.457681 (rank : 75)	θ value	5.81887e-07 (rank : 70)
Query Neighborhood Hits	174	Target Neighborhood Hits	210	Shared Neighborhood Hits	86
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

FANCM_MOUSE
NC score	0.451694 (rank : 76)	θ value	1.43324e-05 (rank : 72)
Query Neighborhood Hits	174	Target Neighborhood Hits	177	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

WRN_MOUSE
NC score	0.446614 (rank : 77)	θ value	0.000121331 (rank : 76)
Query Neighborhood Hits	174	Target Neighborhood Hits	295	Shared Neighborhood Hits	90
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

RECQ1_HUMAN
NC score	0.446168 (rank : 78)	θ value	1.09739e-05 (rank : 71)
Query Neighborhood Hits	174	Target Neighborhood Hits	100	Shared Neighborhood Hits	73
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ1_MOUSE
NC score	0.445637 (rank : 79)	θ value	2.44474e-05 (rank : 74)
Query Neighborhood Hits	174	Target Neighborhood Hits	95	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

DICER_HUMAN
NC score	0.421751 (rank : 80)	θ value	0.00035302 (rank : 79)
Query Neighborhood Hits	174	Target Neighborhood Hits	126	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

DICER_MOUSE
NC score	0.421117 (rank : 81)	θ value	0.00020696 (rank : 77)
Query Neighborhood Hits	174	Target Neighborhood Hits	140	Shared Neighborhood Hits	84
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

LGP2_MOUSE
NC score	0.361698 (rank : 82)	θ value	1.43324e-05 (rank : 73)
Query Neighborhood Hits	174	Target Neighborhood Hits	86	Shared Neighborhood Hits	71
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

IFIH1_HUMAN
NC score	0.351441 (rank : 83)	θ value	0.00869519 (rank : 85)
Query Neighborhood Hits	174	Target Neighborhood Hits	96	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

LGP2_HUMAN
NC score	0.347476 (rank : 84)	θ value	0.000602161 (rank : 81)
Query Neighborhood Hits	174	Target Neighborhood Hits	94	Shared Neighborhood Hits	72
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

IFIH1_MOUSE
NC score	0.337886 (rank : 85)	θ value	0.00228821 (rank : 83)
Query Neighborhood Hits	174	Target Neighborhood Hits	126	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

DDX58_MOUSE
NC score	0.222627 (rank : 86)	θ value	5.27518 (rank : 145)
Query Neighborhood Hits	174	Target Neighborhood Hits	99	Shared Neighborhood Hits	62
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DDX58_HUMAN
NC score	0.186084 (rank : 87)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	174	Target Neighborhood Hits	105	Shared Neighborhood Hits	60
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

CC026_HUMAN
NC score	0.157893 (rank : 88)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	174	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

U520_HUMAN
NC score	0.132790 (rank : 89)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	174	Target Neighborhood Hits	88	Shared Neighborhood Hits	47
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

CC026_MOUSE
NC score	0.126765 (rank : 90)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	174	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

HELC1_HUMAN
NC score	0.100098 (rank : 91)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	174	Target Neighborhood Hits	71	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

SMAL1_HUMAN
NC score	0.074415 (rank : 92)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	174	Target Neighborhood Hits	174	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

SMAL1_MOUSE
NC score	0.050745 (rank : 93)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	174	Target Neighborhood Hits	157	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

CHD4_HUMAN
NC score	0.045624 (rank : 94)	θ value	3.0926 (rank : 123)
Query Neighborhood Hits	174	Target Neighborhood Hits	365	Shared Neighborhood Hits	38
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
NC score	0.045440 (rank : 95)	θ value	3.0926 (rank : 124)
Query Neighborhood Hits	174	Target Neighborhood Hits	408	Shared Neighborhood Hits	42
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD3_HUMAN
NC score	0.039734 (rank : 96)	θ value	0.365318 (rank : 101)
Query Neighborhood Hits	174	Target Neighborhood Hits	397	Shared Neighborhood Hits	35
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

PHF20_MOUSE
NC score	0.039619 (rank : 97)	θ value	1.38821 (rank : 114)
Query Neighborhood Hits	174	Target Neighborhood Hits	513	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

LEO1_MOUSE
NC score	0.037044 (rank : 98)	θ value	1.81305 (rank : 117)
Query Neighborhood Hits	174	Target Neighborhood Hits	946	Shared Neighborhood Hits	51
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LEO1_HUMAN
NC score	0.036591 (rank : 99)	θ value	1.38821 (rank : 113)
Query Neighborhood Hits	174	Target Neighborhood Hits	958	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

ISY1_MOUSE
NC score	0.035594 (rank : 100)	θ value	0.21417 (rank : 94)
Query Neighborhood Hits	174	Target Neighborhood Hits	35	Shared Neighborhood Hits	7
SwissProt Accessions	Q69ZQ2, Q8VDX4, Q9D3E2	Gene names	Kiaa1160
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor ISY1 homolog.

CHD5_HUMAN
NC score	0.034644 (rank : 101)	θ value	3.0926 (rank : 125)
Query Neighborhood Hits	174	Target Neighborhood Hits	349	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

ISY1_HUMAN
NC score	0.034308 (rank : 102)	θ value	0.279714 (rank : 97)
Query Neighborhood Hits	174	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULR0, Q96IL2, Q9BT05	Gene names	KIAA1160
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor ISY1 homolog.

CT2NL_HUMAN
NC score	0.032260 (rank : 103)	θ value	0.279714 (rank : 96)
Query Neighborhood Hits	174	Target Neighborhood Hits	1059	Shared Neighborhood Hits	51
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CMGA_HUMAN
NC score	0.031333 (rank : 104)	θ value	5.27518 (rank : 144)
Query Neighborhood Hits	174	Target Neighborhood Hits	238	Shared Neighborhood Hits	24
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

IWS1_HUMAN
NC score	0.030051 (rank : 105)	θ value	0.125558 (rank : 90)
Query Neighborhood Hits	174	Target Neighborhood Hits	1241	Shared Neighborhood Hits	51
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MPP8_HUMAN
NC score	0.030000 (rank : 106)	θ value	3.0926 (rank : 127)
Query Neighborhood Hits	174	Target Neighborhood Hits	948	Shared Neighborhood Hits	56
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

IWS1_MOUSE
NC score	0.029424 (rank : 107)	θ value	0.279714 (rank : 98)
Query Neighborhood Hits	174	Target Neighborhood Hits	1258	Shared Neighborhood Hits	45
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CT2NL_MOUSE
NC score	0.029377 (rank : 108)	θ value	0.47712 (rank : 103)
Query Neighborhood Hits	174	Target Neighborhood Hits	902	Shared Neighborhood Hits	47
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CYBP_HUMAN
NC score	0.024435 (rank : 109)	θ value	2.36792 (rank : 121)
Query Neighborhood Hits	174	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HB71, O60666	Gene names	CACYBP, S100A6BP, SIP
Domain Architecture
Description	Calcyclin-binding protein (CacyBP) (hCacyBP) (Siah-interacting protein) (S100A6-binding protein).

TCAL5_HUMAN
NC score	0.024202 (rank : 110)	θ value	1.81305 (rank : 118)
Query Neighborhood Hits	174	Target Neighborhood Hits	806	Shared Neighborhood Hits	34
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TCAL3_HUMAN
NC score	0.023606 (rank : 111)	θ value	0.62314 (rank : 107)
Query Neighborhood Hits	174	Target Neighborhood Hits	274	Shared Neighborhood Hits	15
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

CCD41_MOUSE
NC score	0.021043 (rank : 112)	θ value	0.21417 (rank : 92)
Query Neighborhood Hits	174	Target Neighborhood Hits	1399	Shared Neighborhood Hits	57
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

GOGB1_HUMAN
NC score	0.020810 (rank : 113)	θ value	0.21417 (rank : 93)
Query Neighborhood Hits	174	Target Neighborhood Hits	2297	Shared Neighborhood Hits	68
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

GOGA4_HUMAN
NC score	0.020777 (rank : 114)	θ value	0.0736092 (rank : 88)
Query Neighborhood Hits	174	Target Neighborhood Hits	2034	Shared Neighborhood Hits	70
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

MY18A_MOUSE
NC score	0.019733 (rank : 115)	θ value	0.0736092 (rank : 89)
Query Neighborhood Hits	174	Target Neighborhood Hits	1989	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CDC37_HUMAN
NC score	0.019511 (rank : 116)	θ value	2.36792 (rank : 120)
Query Neighborhood Hits	174	Target Neighborhood Hits	506	Shared Neighborhood Hits	33
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

CK5P2_HUMAN
NC score	0.019206 (rank : 117)	θ value	5.27518 (rank : 142)
Query Neighborhood Hits	174	Target Neighborhood Hits	1433	Shared Neighborhood Hits	58
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

MY18A_HUMAN
NC score	0.019001 (rank : 118)	θ value	0.47712 (rank : 104)
Query Neighborhood Hits	174	Target Neighborhood Hits	1929	Shared Neighborhood Hits	74
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

IF3A_HUMAN
NC score	0.018772 (rank : 119)	θ value	4.03905 (rank : 136)
Query Neighborhood Hits	174	Target Neighborhood Hits	875	Shared Neighborhood Hits	52
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

EPN4_MOUSE
NC score	0.018648 (rank : 120)	θ value	1.81305 (rank : 116)
Query Neighborhood Hits	174	Target Neighborhood Hits	58	Shared Neighborhood Hits	8
SwissProt Accessions	Q99KN9, Q8CFH4	Gene names	Clint1, Enth, Epn4, Epnr, Kiaa0171
Domain Architecture
Description	Clathrin interactor 1 (Epsin-4) (Epsin-related protein) (EpsinR) (Enthoprotin).

TPR_HUMAN
NC score	0.018431 (rank : 121)	θ value	0.00869519 (rank : 86)
Query Neighborhood Hits	174	Target Neighborhood Hits	1921	Shared Neighborhood Hits	63
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

AZI1_HUMAN
NC score	0.018187 (rank : 122)	θ value	0.365318 (rank : 100)
Query Neighborhood Hits	174	Target Neighborhood Hits	1000	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

IF3A_MOUSE
NC score	0.018126 (rank : 123)	θ value	5.27518 (rank : 147)
Query Neighborhood Hits	174	Target Neighborhood Hits	871	Shared Neighborhood Hits	52
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

CP250_HUMAN
NC score	0.018035 (rank : 124)	θ value	0.00175202 (rank : 82)
Query Neighborhood Hits	174	Target Neighborhood Hits	1805	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

RRBP1_HUMAN
NC score	0.017991 (rank : 125)	θ value	4.03905 (rank : 141)
Query Neighborhood Hits	174	Target Neighborhood Hits	1306	Shared Neighborhood Hits	60
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

XRCC4_HUMAN
NC score	0.017957 (rank : 126)	θ value	0.365318 (rank : 102)
Query Neighborhood Hits	174	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	Q13426, Q9BS72, Q9UP94	Gene names	XRCC4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

LRRF1_HUMAN
NC score	0.017851 (rank : 127)	θ value	1.06291 (rank : 112)
Query Neighborhood Hits	174	Target Neighborhood Hits	625	Shared Neighborhood Hits	44
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

CJ118_MOUSE
NC score	0.017603 (rank : 128)	θ value	0.279714 (rank : 95)
Query Neighborhood Hits	174	Target Neighborhood Hits	1132	Shared Neighborhood Hits	49
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CN044_HUMAN
NC score	0.017187 (rank : 129)	θ value	0.813845 (rank : 109)
Query Neighborhood Hits	174	Target Neighborhood Hits	227	Shared Neighborhood Hits	21
SwissProt Accessions	Q96MY7	Gene names	C14orf44
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf44.

MYH9_MOUSE
NC score	0.017172 (rank : 130)	θ value	0.279714 (rank : 99)
Query Neighborhood Hits	174	Target Neighborhood Hits	1829	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

SMC3_MOUSE
NC score	0.016316 (rank : 131)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	174	Target Neighborhood Hits	1187	Shared Neighborhood Hits	55
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SMC3_HUMAN
NC score	0.016210 (rank : 132)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	174	Target Neighborhood Hits	1186	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

CA051_MOUSE
NC score	0.016100 (rank : 133)	θ value	2.36792 (rank : 119)
Query Neighborhood Hits	174	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q3TQ03, Q3U1B8	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf51 homolog.

SM1L2_MOUSE
NC score	0.016053 (rank : 134)	θ value	6.88961 (rank : 161)
Query Neighborhood Hits	174	Target Neighborhood Hits	918	Shared Neighborhood Hits	48
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

EPN4_HUMAN
NC score	0.016013 (rank : 135)	θ value	4.03905 (rank : 134)
Query Neighborhood Hits	174	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q14677, Q8NAF1, Q96E05	Gene names	CLINT1, ENTH, EPN4, EPNR, KIAA0171
Domain Architecture
Description	Clathrin interactor 1 (Epsin-4) (Epsin-related protein) (EpsinR) (Enthoprotin) (Clathrin-interacting protein localized in the trans- Golgi region) (Clint).

MYH9_HUMAN
NC score	0.015554 (rank : 136)	θ value	0.47712 (rank : 105)
Query Neighborhood Hits	174	Target Neighborhood Hits	1762	Shared Neighborhood Hits	60
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

HMMR_MOUSE
NC score	0.015056 (rank : 137)	θ value	5.27518 (rank : 146)
Query Neighborhood Hits	174	Target Neighborhood Hits	1178	Shared Neighborhood Hits	55
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

OVGP1_HUMAN
NC score	0.014950 (rank : 138)	θ value	0.163984 (rank : 91)
Query Neighborhood Hits	174	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q12889, Q15841	Gene names	OVGP1, MUC9, OGP
Domain Architecture
Description	Oviduct-specific glycoprotein precursor (Oviductal glycoprotein) (Oviductin) (Estrogen-dependent oviduct protein) (Mucin 9).

TUFT1_MOUSE
NC score	0.014845 (rank : 139)	θ value	6.88961 (rank : 163)
Query Neighborhood Hits	174	Target Neighborhood Hits	732	Shared Neighborhood Hits	43
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

NIN_HUMAN
NC score	0.014626 (rank : 140)	θ value	0.62314 (rank : 106)
Query Neighborhood Hits	174	Target Neighborhood Hits	1416	Shared Neighborhood Hits	52
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

CING_HUMAN
NC score	0.014559 (rank : 141)	θ value	6.88961 (rank : 152)
Query Neighborhood Hits	174	Target Neighborhood Hits	1275	Shared Neighborhood Hits	50
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CKAP4_HUMAN
NC score	0.014324 (rank : 142)	θ value	5.27518 (rank : 143)
Query Neighborhood Hits	174	Target Neighborhood Hits	592	Shared Neighborhood Hits	37
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

TPM4_MOUSE
NC score	0.014176 (rank : 143)	θ value	1.38821 (rank : 115)
Query Neighborhood Hits	174	Target Neighborhood Hits	703	Shared Neighborhood Hits	44
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

CCD21_HUMAN
NC score	0.014137 (rank : 144)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	174	Target Neighborhood Hits	1228	Shared Neighborhood Hits	57
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CEP63_HUMAN
NC score	0.013611 (rank : 145)	θ value	0.813845 (rank : 108)
Query Neighborhood Hits	174	Target Neighborhood Hits	1005	Shared Neighborhood Hits	44
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

HMGN1_HUMAN
NC score	0.013606 (rank : 146)	θ value	4.03905 (rank : 135)
Query Neighborhood Hits	174	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	P05114, Q3KQR8	Gene names	HMGN1, HMG14
Domain Architecture	No domain graphic available
Description	Nonhistone chromosomal protein HMG-14 (High-mobility group nucleosome- binding domain-containing protein 1).

MYRIP_MOUSE
NC score	0.013590 (rank : 147)	θ value	4.03905 (rank : 138)
Query Neighborhood Hits	174	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

SETX_HUMAN
NC score	0.013467 (rank : 148)	θ value	6.88961 (rank : 160)
Query Neighborhood Hits	174	Target Neighborhood Hits	368	Shared Neighborhood Hits	24
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

ERC2_MOUSE
NC score	0.012791 (rank : 149)	θ value	6.88961 (rank : 155)
Query Neighborhood Hits	174	Target Neighborhood Hits	1166	Shared Neighborhood Hits	52
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

ERC2_HUMAN
NC score	0.012637 (rank : 150)	θ value	6.88961 (rank : 154)
Query Neighborhood Hits	174	Target Neighborhood Hits	1156	Shared Neighborhood Hits	52
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

CKAP4_MOUSE
NC score	0.012617 (rank : 151)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	174	Target Neighborhood Hits	596	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

MYH2_HUMAN
NC score	0.012516 (rank : 152)	θ value	5.27518 (rank : 148)
Query Neighborhood Hits	174	Target Neighborhood Hits	1491	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

HDAC9_MOUSE
NC score	0.012136 (rank : 153)	θ value	1.06291 (rank : 111)
Query Neighborhood Hits	174	Target Neighborhood Hits	186	Shared Neighborhood Hits	17
SwissProt Accessions	Q99N13, Q9EPT2	Gene names	Hdac9, Hdac7b, Hdrp, Mitr
Domain Architecture	No domain graphic available
Description	Histone deacetylase 9 (HD9) (HD7B) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR).

ZWINT_HUMAN
NC score	0.011535 (rank : 154)	θ value	8.99809 (rank : 174)
Query Neighborhood Hits	174	Target Neighborhood Hits	333	Shared Neighborhood Hits	30
SwissProt Accessions	O95229, Q9BWD0	Gene names	ZWINT
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

CP135_HUMAN
NC score	0.011460 (rank : 155)	θ value	6.88961 (rank : 153)
Query Neighborhood Hits	174	Target Neighborhood Hits	1290	Shared Neighborhood Hits	49
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

MYRIP_HUMAN
NC score	0.011029 (rank : 156)	θ value	3.0926 (rank : 128)
Query Neighborhood Hits	174	Target Neighborhood Hits	269	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

HIP1R_MOUSE
NC score	0.010948 (rank : 157)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	174	Target Neighborhood Hits	959	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

RN169_HUMAN
NC score	0.010889 (rank : 158)	θ value	4.03905 (rank : 140)
Query Neighborhood Hits	174	Target Neighborhood Hits	203	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

PHF14_HUMAN
NC score	0.010831 (rank : 159)	θ value	2.36792 (rank : 122)
Query Neighborhood Hits	174	Target Neighborhood Hits	447	Shared Neighborhood Hits	40
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

KI21A_HUMAN
NC score	0.010675 (rank : 160)	θ value	4.03905 (rank : 137)
Query Neighborhood Hits	174	Target Neighborhood Hits	1543	Shared Neighborhood Hits	61
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

DYH5_MOUSE
NC score	0.010631 (rank : 161)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	174	Target Neighborhood Hits	286	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VHE6, Q8BWG1	Gene names	Dnah5, Dnahc5
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (Mdnah5).

AKAP9_HUMAN
NC score	0.010004 (rank : 162)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	174	Target Neighborhood Hits	1710	Shared Neighborhood Hits	55
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

NDUB5_HUMAN
NC score	0.009968 (rank : 163)	θ value	4.03905 (rank : 139)
Query Neighborhood Hits	174	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	O43674	Gene names	NDUFB5
Domain Architecture	No domain graphic available
Description	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial precursor (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase SGDH subunit) (Complex I-SGDH) (CI-SGDH).

SETD2_HUMAN
NC score	0.009529 (rank : 164)	θ value	6.88961 (rank : 159)
Query Neighborhood Hits	174	Target Neighborhood Hits	412	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

IFIT3_HUMAN
NC score	0.008299 (rank : 165)	θ value	0.813845 (rank : 110)
Query Neighborhood Hits	174	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	O14879, Q99634, Q9BSK7	Gene names	IFIT3, IFI60, IFIT4
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (IFIT-4) (Interferon-induced 60 kDa protein) (IFI-60K) (ISG-60) (CIG49) (Retinoic acid-induced gene G protein) (RIG-G).

ALO17_HUMAN
NC score	0.007959 (rank : 166)	θ value	4.03905 (rank : 132)
Query Neighborhood Hits	174	Target Neighborhood Hits	317	Shared Neighborhood Hits	15
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

ANR26_MOUSE
NC score	0.006729 (rank : 167)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	174	Target Neighborhood Hits	1554	Shared Neighborhood Hits	53
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

RGNEF_MOUSE
NC score	0.005841 (rank : 168)	θ value	5.27518 (rank : 149)
Query Neighborhood Hits	174	Target Neighborhood Hits	641	Shared Neighborhood Hits	38
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

PARP1_MOUSE
NC score	0.005717 (rank : 169)	θ value	3.0926 (rank : 129)
Query Neighborhood Hits	174	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

ADA30_HUMAN
NC score	0.005412 (rank : 170)	θ value	4.03905 (rank : 131)
Query Neighborhood Hits	174	Target Neighborhood Hits	391	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

UBE3C_HUMAN
NC score	0.005074 (rank : 171)	θ value	3.0926 (rank : 130)
Query Neighborhood Hits	174	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

UBE3C_MOUSE
NC score	0.004616 (rank : 172)	θ value	5.27518 (rank : 150)
Query Neighborhood Hits	174	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

C1TC_HUMAN
NC score	0.004510 (rank : 173)	θ value	6.88961 (rank : 151)
Query Neighborhood Hits	174	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	P11586, Q86VC9, Q9BVP5	Gene names	MTHFD1, MTHFC, MTHFD
Domain Architecture
Description	C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF synthase) [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)].

TTC1_HUMAN
NC score	0.004334 (rank : 174)	θ value	6.88961 (rank : 162)
Query Neighborhood Hits	174	Target Neighborhood Hits	417	Shared Neighborhood Hits	20
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

HERC2_HUMAN
NC score	0.003215 (rank : 175)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	174	Target Neighborhood Hits	163	Shared Neighborhood Hits	9
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

MTSS1_MOUSE
NC score	0.002574 (rank : 176)	θ value	6.88961 (rank : 156)
Query Neighborhood Hits	174	Target Neighborhood Hits	592	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

IRX2_HUMAN
NC score	0.002444 (rank : 177)	θ value	3.0926 (rank : 126)
Query Neighborhood Hits	174	Target Neighborhood Hits	358	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BZI1, Q7Z2I7	Gene names	IRX2, IRXA2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-2 (Iroquois homeobox protein 2) (Homeodomain protein IRXA2).

BCAR1_HUMAN
NC score	0.002120 (rank : 178)	θ value	4.03905 (rank : 133)
Query Neighborhood Hits	174	Target Neighborhood Hits	554	Shared Neighborhood Hits	4
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

K2C5_MOUSE
NC score	0.002078 (rank : 179)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	174	Target Neighborhood Hits	505	Shared Neighborhood Hits	34
SwissProt Accessions	Q922U2, Q920F2	Gene names	Krt5, Krt2-5
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5).

NOTC2_MOUSE
NC score	-0.005626 (rank : 180)	θ value	6.88961 (rank : 157)
Query Neighborhood Hits	174	Target Neighborhood Hits	1069	Shared Neighborhood Hits	7
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PEG3_MOUSE
NC score	-0.006061 (rank : 181)	θ value	6.88961 (rank : 158)
Query Neighborhood Hits	174	Target Neighborhood Hits	1101	Shared Neighborhood Hits	16
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).