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Network neighborhood for query Sequence : RECQ4_HUMAN

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RECQ4_HUMAN
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RECQ4_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	177	Target Neighborhood Hits	177	Shared Neighborhood Hits	177
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RECQ4_MOUSE
θ value	0 (rank : 2)	NC score	0.966352 (rank : 2)
Query Neighborhood Hits	177	Target Neighborhood Hits	206	Shared Neighborhood Hits	94
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

RECQ5_HUMAN
θ value	4.86918e-46 (rank : 3)	NC score	0.813979 (rank : 7)
Query Neighborhood Hits	177	Target Neighborhood Hits	390	Shared Neighborhood Hits	98
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

RECQ1_HUMAN
θ value	4.2656e-42 (rank : 4)	NC score	0.838152 (rank : 3)
Query Neighborhood Hits	177	Target Neighborhood Hits	100	Shared Neighborhood Hits	78
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ1_MOUSE
θ value	4.2656e-42 (rank : 5)	NC score	0.837816 (rank : 4)
Query Neighborhood Hits	177	Target Neighborhood Hits	95	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

WRN_MOUSE
θ value	7.27602e-42 (rank : 6)	NC score	0.788967 (rank : 9)
Query Neighborhood Hits	177	Target Neighborhood Hits	295	Shared Neighborhood Hits	82
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

BLM_MOUSE
θ value	1.62093e-41 (rank : 7)	NC score	0.823777 (rank : 5)
Query Neighborhood Hits	177	Target Neighborhood Hits	108	Shared Neighborhood Hits	73
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

BLM_HUMAN
θ value	2.11701e-41 (rank : 8)	NC score	0.817840 (rank : 6)
Query Neighborhood Hits	177	Target Neighborhood Hits	148	Shared Neighborhood Hits	75
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

WRN_HUMAN
θ value	3.61106e-41 (rank : 9)	NC score	0.808735 (rank : 8)
Query Neighborhood Hits	177	Target Neighborhood Hits	132	Shared Neighborhood Hits	83
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

DDX43_HUMAN
θ value	1.33837e-11 (rank : 10)	NC score	0.601679 (rank : 14)
Query Neighborhood Hits	177	Target Neighborhood Hits	120	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX46_HUMAN
θ value	1.133e-10 (rank : 11)	NC score	0.596210 (rank : 15)
Query Neighborhood Hits	177	Target Neighborhood Hits	357	Shared Neighborhood Hits	92
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
θ value	1.133e-10 (rank : 12)	NC score	0.595265 (rank : 16)
Query Neighborhood Hits	177	Target Neighborhood Hits	358	Shared Neighborhood Hits	94
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX5_HUMAN
θ value	7.34386e-10 (rank : 13)	NC score	0.605772 (rank : 13)
Query Neighborhood Hits	177	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
θ value	9.59137e-10 (rank : 14)	NC score	0.605845 (rank : 12)
Query Neighborhood Hits	177	Target Neighborhood Hits	101	Shared Neighborhood Hits	85
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX17_HUMAN
θ value	1.63604e-09 (rank : 15)	NC score	0.606060 (rank : 10)
Query Neighborhood Hits	177	Target Neighborhood Hits	104	Shared Neighborhood Hits	87
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX17_MOUSE
θ value	1.63604e-09 (rank : 16)	NC score	0.605918 (rank : 11)
Query Neighborhood Hits	177	Target Neighborhood Hits	105	Shared Neighborhood Hits	85
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX49_HUMAN
θ value	4.76016e-09 (rank : 17)	NC score	0.570171 (rank : 30)
Query Neighborhood Hits	177	Target Neighborhood Hits	223	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX41_HUMAN
θ value	1.80886e-08 (rank : 18)	NC score	0.587135 (rank : 17)
Query Neighborhood Hits	177	Target Neighborhood Hits	111	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX50_HUMAN
θ value	3.08544e-08 (rank : 19)	NC score	0.587027 (rank : 18)
Query Neighborhood Hits	177	Target Neighborhood Hits	132	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_MOUSE
θ value	3.08544e-08 (rank : 20)	NC score	0.586439 (rank : 19)
Query Neighborhood Hits	177	Target Neighborhood Hits	137	Shared Neighborhood Hits	86
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX49_MOUSE
θ value	4.0297e-08 (rank : 21)	NC score	0.571957 (rank : 26)
Query Neighborhood Hits	177	Target Neighborhood Hits	119	Shared Neighborhood Hits	87
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX41_MOUSE
θ value	5.26297e-08 (rank : 22)	NC score	0.584967 (rank : 20)
Query Neighborhood Hits	177	Target Neighborhood Hits	115	Shared Neighborhood Hits	86
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX48_HUMAN
θ value	5.26297e-08 (rank : 23)	NC score	0.571252 (rank : 27)
Query Neighborhood Hits	177	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
θ value	5.26297e-08 (rank : 24)	NC score	0.571043 (rank : 28)
Query Neighborhood Hits	177	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX4_MOUSE
θ value	5.26297e-08 (rank : 25)	NC score	0.560609 (rank : 38)
Query Neighborhood Hits	177	Target Neighborhood Hits	100	Shared Neighborhood Hits	87
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX53_HUMAN
θ value	5.26297e-08 (rank : 26)	NC score	0.573055 (rank : 25)
Query Neighborhood Hits	177	Target Neighborhood Hits	124	Shared Neighborhood Hits	82
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX21_MOUSE
θ value	1.17247e-07 (rank : 27)	NC score	0.569575 (rank : 31)
Query Neighborhood Hits	177	Target Neighborhood Hits	350	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX21_HUMAN
θ value	2.61198e-07 (rank : 28)	NC score	0.575052 (rank : 23)
Query Neighborhood Hits	177	Target Neighborhood Hits	308	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX4_HUMAN
θ value	7.59969e-07 (rank : 29)	NC score	0.559412 (rank : 42)
Query Neighborhood Hits	177	Target Neighborhood Hits	123	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX6_HUMAN
θ value	1.29631e-06 (rank : 30)	NC score	0.580553 (rank : 21)
Query Neighborhood Hits	177	Target Neighborhood Hits	97	Shared Neighborhood Hits	89
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
θ value	1.29631e-06 (rank : 31)	NC score	0.580342 (rank : 22)
Query Neighborhood Hits	177	Target Neighborhood Hits	98	Shared Neighborhood Hits	89
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

IF4A2_HUMAN
θ value	1.29631e-06 (rank : 32)	NC score	0.559545 (rank : 40)
Query Neighborhood Hits	177	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
θ value	1.29631e-06 (rank : 33)	NC score	0.559545 (rank : 41)
Query Neighborhood Hits	177	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX47_HUMAN
θ value	2.21117e-06 (rank : 34)	NC score	0.563791 (rank : 36)
Query Neighborhood Hits	177	Target Neighborhood Hits	97	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_MOUSE
θ value	2.21117e-06 (rank : 35)	NC score	0.563965 (rank : 35)
Query Neighborhood Hits	177	Target Neighborhood Hits	97	Shared Neighborhood Hits	85
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

IF4A1_HUMAN
θ value	2.21117e-06 (rank : 36)	NC score	0.557783 (rank : 43)
Query Neighborhood Hits	177	Target Neighborhood Hits	106	Shared Neighborhood Hits	85
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
θ value	2.21117e-06 (rank : 37)	NC score	0.557783 (rank : 44)
Query Neighborhood Hits	177	Target Neighborhood Hits	106	Shared Neighborhood Hits	85
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

DDX39_MOUSE
θ value	6.43352e-06 (rank : 38)	NC score	0.553913 (rank : 49)
Query Neighborhood Hits	177	Target Neighborhood Hits	97	Shared Neighborhood Hits	85
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX39_HUMAN
θ value	8.40245e-06 (rank : 39)	NC score	0.555389 (rank : 46)
Query Neighborhood Hits	177	Target Neighborhood Hits	94	Shared Neighborhood Hits	85
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

UAP56_HUMAN
θ value	8.40245e-06 (rank : 40)	NC score	0.547523 (rank : 50)
Query Neighborhood Hits	177	Target Neighborhood Hits	96	Shared Neighborhood Hits	85
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
θ value	8.40245e-06 (rank : 41)	NC score	0.547444 (rank : 52)
Query Neighborhood Hits	177	Target Neighborhood Hits	96	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX51_HUMAN
θ value	1.09739e-05 (rank : 42)	NC score	0.536650 (rank : 53)
Query Neighborhood Hits	177	Target Neighborhood Hits	332	Shared Neighborhood Hits	98
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX31_HUMAN
θ value	1.43324e-05 (rank : 43)	NC score	0.547497 (rank : 51)
Query Neighborhood Hits	177	Target Neighborhood Hits	132	Shared Neighborhood Hits	89
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX3Y_HUMAN
θ value	1.43324e-05 (rank : 44)	NC score	0.564319 (rank : 33)
Query Neighborhood Hits	177	Target Neighborhood Hits	121	Shared Neighborhood Hits	85
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX52_HUMAN
θ value	1.43324e-05 (rank : 45)	NC score	0.574000 (rank : 24)
Query Neighborhood Hits	177	Target Neighborhood Hits	107	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX51_MOUSE
θ value	2.44474e-05 (rank : 46)	NC score	0.535115 (rank : 54)
Query Neighborhood Hits	177	Target Neighborhood Hits	130	Shared Neighborhood Hits	89
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX3X_HUMAN
θ value	3.19293e-05 (rank : 47)	NC score	0.564032 (rank : 34)
Query Neighborhood Hits	177	Target Neighborhood Hits	122	Shared Neighborhood Hits	85
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX3X_MOUSE
θ value	3.19293e-05 (rank : 48)	NC score	0.564949 (rank : 32)
Query Neighborhood Hits	177	Target Neighborhood Hits	117	Shared Neighborhood Hits	85
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

PL10_MOUSE
θ value	3.19293e-05 (rank : 49)	NC score	0.563092 (rank : 37)
Query Neighborhood Hits	177	Target Neighborhood Hits	120	Shared Neighborhood Hits	85
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3Y_MOUSE
θ value	7.1131e-05 (rank : 50)	NC score	0.560233 (rank : 39)
Query Neighborhood Hits	177	Target Neighborhood Hits	126	Shared Neighborhood Hits	86
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX27_HUMAN
θ value	0.000158464 (rank : 51)	NC score	0.554214 (rank : 48)
Query Neighborhood Hits	177	Target Neighborhood Hits	197	Shared Neighborhood Hits	85
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_MOUSE
θ value	0.00035302 (rank : 52)	NC score	0.555652 (rank : 45)
Query Neighborhood Hits	177	Target Neighborhood Hits	174	Shared Neighborhood Hits	85
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX18_MOUSE
θ value	0.000461057 (rank : 53)	NC score	0.510291 (rank : 67)
Query Neighborhood Hits	177	Target Neighborhood Hits	115	Shared Neighborhood Hits	82
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

LGP2_MOUSE
θ value	0.000786445 (rank : 54)	NC score	0.278917 (rank : 81)
Query Neighborhood Hits	177	Target Neighborhood Hits	86	Shared Neighborhood Hits	70
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

DDX1_HUMAN
θ value	0.00134147 (rank : 55)	NC score	0.519520 (rank : 64)
Query Neighborhood Hits	177	Target Neighborhood Hits	110	Shared Neighborhood Hits	83
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX52_MOUSE
θ value	0.00134147 (rank : 56)	NC score	0.570189 (rank : 29)
Query Neighborhood Hits	177	Target Neighborhood Hits	101	Shared Neighborhood Hits	87
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

LGP2_HUMAN
θ value	0.00134147 (rank : 57)	NC score	0.280212 (rank : 80)
Query Neighborhood Hits	177	Target Neighborhood Hits	94	Shared Neighborhood Hits	73
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

OGFR_HUMAN
θ value	0.00134147 (rank : 58)	NC score	0.047428 (rank : 101)
Query Neighborhood Hits	177	Target Neighborhood Hits	1582	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

DDX1_MOUSE
θ value	0.00228821 (rank : 59)	NC score	0.520915 (rank : 62)
Query Neighborhood Hits	177	Target Neighborhood Hits	112	Shared Neighborhood Hits	83
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX23_HUMAN
θ value	0.00390308 (rank : 60)	NC score	0.554833 (rank : 47)
Query Neighborhood Hits	177	Target Neighborhood Hits	486	Shared Neighborhood Hits	90
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

SYN1_HUMAN
θ value	0.00390308 (rank : 61)	NC score	0.075721 (rank : 94)
Query Neighborhood Hits	177	Target Neighborhood Hits	419	Shared Neighborhood Hits	45
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

DDX28_MOUSE
θ value	0.00509761 (rank : 62)	NC score	0.529498 (rank : 57)
Query Neighborhood Hits	177	Target Neighborhood Hits	112	Shared Neighborhood Hits	87
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

HELC1_HUMAN
θ value	0.00509761 (rank : 63)	NC score	0.193692 (rank : 87)
Query Neighborhood Hits	177	Target Neighborhood Hits	71	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

DDX20_MOUSE
θ value	0.00665767 (rank : 64)	NC score	0.517453 (rank : 65)
Query Neighborhood Hits	177	Target Neighborhood Hits	177	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX10_MOUSE
θ value	0.00869519 (rank : 65)	NC score	0.524994 (rank : 61)
Query Neighborhood Hits	177	Target Neighborhood Hits	233	Shared Neighborhood Hits	85
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX18_HUMAN
θ value	0.00869519 (rank : 66)	NC score	0.512171 (rank : 66)
Query Neighborhood Hits	177	Target Neighborhood Hits	124	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX20_HUMAN
θ value	0.00869519 (rank : 67)	NC score	0.520227 (rank : 63)
Query Neighborhood Hits	177	Target Neighborhood Hits	121	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX24_MOUSE
θ value	0.00869519 (rank : 68)	NC score	0.529358 (rank : 58)
Query Neighborhood Hits	177	Target Neighborhood Hits	147	Shared Neighborhood Hits	87
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DD19A_MOUSE
θ value	0.0113563 (rank : 69)	NC score	0.503592 (rank : 72)
Query Neighborhood Hits	177	Target Neighborhood Hits	105	Shared Neighborhood Hits	83
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DD19A_HUMAN
θ value	0.0148317 (rank : 70)	NC score	0.504140 (rank : 70)
Query Neighborhood Hits	177	Target Neighborhood Hits	107	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19B_HUMAN
θ value	0.0148317 (rank : 71)	NC score	0.503574 (rank : 73)
Query Neighborhood Hits	177	Target Neighborhood Hits	109	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DDX10_HUMAN
θ value	0.0148317 (rank : 72)	NC score	0.525703 (rank : 60)
Query Neighborhood Hits	177	Target Neighborhood Hits	210	Shared Neighborhood Hits	84
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX54_HUMAN
θ value	0.0148317 (rank : 73)	NC score	0.530729 (rank : 56)
Query Neighborhood Hits	177	Target Neighborhood Hits	170	Shared Neighborhood Hits	89
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX24_HUMAN
θ value	0.0193708 (rank : 74)	NC score	0.526881 (rank : 59)
Query Neighborhood Hits	177	Target Neighborhood Hits	190	Shared Neighborhood Hits	87
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DICER_MOUSE
θ value	0.0193708 (rank : 75)	NC score	0.292864 (rank : 78)
Query Neighborhood Hits	177	Target Neighborhood Hits	140	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

DDX55_HUMAN
θ value	0.0252991 (rank : 76)	NC score	0.503655 (rank : 71)
Query Neighborhood Hits	177	Target Neighborhood Hits	122	Shared Neighborhood Hits	83
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX55_MOUSE
θ value	0.0252991 (rank : 77)	NC score	0.505720 (rank : 69)
Query Neighborhood Hits	177	Target Neighborhood Hits	111	Shared Neighborhood Hits	85
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DICER_HUMAN
θ value	0.0252991 (rank : 78)	NC score	0.290835 (rank : 79)
Query Neighborhood Hits	177	Target Neighborhood Hits	126	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

DDX25_HUMAN
θ value	0.0330416 (rank : 79)	NC score	0.503552 (rank : 74)
Query Neighborhood Hits	177	Target Neighborhood Hits	93	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX25_MOUSE
θ value	0.0330416 (rank : 80)	NC score	0.501344 (rank : 75)
Query Neighborhood Hits	177	Target Neighborhood Hits	98	Shared Neighborhood Hits	81
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

ULK1_MOUSE
θ value	0.0330416 (rank : 81)	NC score	0.002877 (rank : 172)
Query Neighborhood Hits	177	Target Neighborhood Hits	1214	Shared Neighborhood Hits	28
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

SYN1_MOUSE
θ value	0.0431538 (rank : 82)	NC score	0.067051 (rank : 95)
Query Neighborhood Hits	177	Target Neighborhood Hits	363	Shared Neighborhood Hits	41
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

DDX56_MOUSE
θ value	0.125558 (rank : 83)	NC score	0.486970 (rank : 76)
Query Neighborhood Hits	177	Target Neighborhood Hits	87	Shared Neighborhood Hits	74
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

K1802_MOUSE
θ value	0.125558 (rank : 84)	NC score	0.025054 (rank : 121)
Query Neighborhood Hits	177	Target Neighborhood Hits	1596	Shared Neighborhood Hits	46
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

DDX54_MOUSE
θ value	0.163984 (rank : 85)	NC score	0.530757 (rank : 55)
Query Neighborhood Hits	177	Target Neighborhood Hits	124	Shared Neighborhood Hits	88
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

FANCM_HUMAN
θ value	0.163984 (rank : 86)	NC score	0.278510 (rank : 82)
Query Neighborhood Hits	177	Target Neighborhood Hits	210	Shared Neighborhood Hits	80
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

CROCC_HUMAN
θ value	0.21417 (rank : 87)	NC score	0.008679 (rank : 158)
Query Neighborhood Hits	177	Target Neighborhood Hits	1409	Shared Neighborhood Hits	23
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

DDX28_HUMAN
θ value	0.21417 (rank : 88)	NC score	0.509645 (rank : 68)
Query Neighborhood Hits	177	Target Neighborhood Hits	103	Shared Neighborhood Hits	82
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

IFIH1_HUMAN
θ value	0.21417 (rank : 89)	NC score	0.263049 (rank : 84)
Query Neighborhood Hits	177	Target Neighborhood Hits	96	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

IFIH1_MOUSE
θ value	0.21417 (rank : 90)	NC score	0.255645 (rank : 85)
Query Neighborhood Hits	177	Target Neighborhood Hits	126	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

PRRT3_HUMAN
θ value	0.21417 (rank : 91)	NC score	0.037494 (rank : 108)
Query Neighborhood Hits	177	Target Neighborhood Hits	998	Shared Neighborhood Hits	46
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RP1L1_HUMAN
θ value	0.21417 (rank : 92)	NC score	0.042723 (rank : 105)
Query Neighborhood Hits	177	Target Neighborhood Hits	1072	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

DDX56_HUMAN
θ value	0.279714 (rank : 93)	NC score	0.485039 (rank : 77)
Query Neighborhood Hits	177	Target Neighborhood Hits	77	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

SKIV2_HUMAN
θ value	0.279714 (rank : 94)	NC score	0.118705 (rank : 90)
Query Neighborhood Hits	177	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	Q15477, O15005, Q12902, Q15476	Gene names	SKIV2L, DDX13, SKI2W, SKIV2, W
Domain Architecture
Description	Helicase SKI2W (EC 3.6.1.-) (Helicase-like protein) (HLP).

RTN4R_HUMAN
θ value	0.365318 (rank : 95)	NC score	0.007065 (rank : 162)
Query Neighborhood Hits	177	Target Neighborhood Hits	271	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZR6	Gene names	RTN4R, NOGOR
Domain Architecture
Description	Reticulon-4 receptor precursor (Nogo receptor) (NgR) (Nogo-66 receptor).

SK2L2_HUMAN
θ value	0.365318 (rank : 96)	NC score	0.102453 (rank : 91)
Query Neighborhood Hits	177	Target Neighborhood Hits	36	Shared Neighborhood Hits	17
SwissProt Accessions	P42285, Q8TAG2	Gene names	SKIV2L2, KIAA0052
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SK2L2_MOUSE
θ value	0.365318 (rank : 97)	NC score	0.101174 (rank : 92)
Query Neighborhood Hits	177	Target Neighborhood Hits	45	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CZU3	Gene names	Skiv2l2
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SPEG_MOUSE
θ value	0.365318 (rank : 98)	NC score	0.006933 (rank : 163)
Query Neighborhood Hits	177	Target Neighborhood Hits	1959	Shared Neighborhood Hits	51
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

MLL3_MOUSE
θ value	0.47712 (rank : 99)	NC score	0.032563 (rank : 111)
Query Neighborhood Hits	177	Target Neighborhood Hits	1399	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

U520_HUMAN
θ value	0.47712 (rank : 100)	NC score	0.204930 (rank : 86)
Query Neighborhood Hits	177	Target Neighborhood Hits	88	Shared Neighborhood Hits	47
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

BAT2_HUMAN
θ value	0.62314 (rank : 101)	NC score	0.043005 (rank : 104)
Query Neighborhood Hits	177	Target Neighborhood Hits	931	Shared Neighborhood Hits	51
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

FANCM_MOUSE
θ value	0.813845 (rank : 102)	NC score	0.275284 (rank : 83)
Query Neighborhood Hits	177	Target Neighborhood Hits	177	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

MEFV_HUMAN
θ value	0.813845 (rank : 103)	NC score	0.010121 (rank : 153)
Query Neighborhood Hits	177	Target Neighborhood Hits	431	Shared Neighborhood Hits	19
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

MLL3_HUMAN
θ value	0.813845 (rank : 104)	NC score	0.031390 (rank : 112)
Query Neighborhood Hits	177	Target Neighborhood Hits	1644	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

ZIM10_MOUSE
θ value	0.813845 (rank : 105)	NC score	0.025454 (rank : 120)
Query Neighborhood Hits	177	Target Neighborhood Hits	430	Shared Neighborhood Hits	27
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ATS19_MOUSE
θ value	1.06291 (rank : 106)	NC score	0.007690 (rank : 161)
Query Neighborhood Hits	177	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

COIA1_HUMAN
θ value	1.06291 (rank : 107)	NC score	0.020979 (rank : 129)
Query Neighborhood Hits	177	Target Neighborhood Hits	447	Shared Neighborhood Hits	28
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CSKI2_MOUSE
θ value	1.06291 (rank : 108)	NC score	0.013146 (rank : 146)
Query Neighborhood Hits	177	Target Neighborhood Hits	812	Shared Neighborhood Hits	39
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

IER5_MOUSE
θ value	1.06291 (rank : 109)	NC score	0.037939 (rank : 107)
Query Neighborhood Hits	177	Target Neighborhood Hits	110	Shared Neighborhood Hits	12
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

MAGE1_HUMAN
θ value	1.06291 (rank : 110)	NC score	0.017216 (rank : 135)
Query Neighborhood Hits	177	Target Neighborhood Hits	1389	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

ARMX2_MOUSE
θ value	1.38821 (rank : 111)	NC score	0.021273 (rank : 126)
Query Neighborhood Hits	177	Target Neighborhood Hits	349	Shared Neighborhood Hits	23
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

CAN9_MOUSE
θ value	1.38821 (rank : 112)	NC score	0.008122 (rank : 159)
Query Neighborhood Hits	177	Target Neighborhood Hits	73	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D805, O35919	Gene names	Capn9, Ncl4
Domain Architecture
Description	Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (nCL-4).

MDC1_MOUSE
θ value	1.38821 (rank : 113)	NC score	0.028709 (rank : 114)
Query Neighborhood Hits	177	Target Neighborhood Hits	998	Shared Neighborhood Hits	39
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

GP157_HUMAN
θ value	1.81305 (rank : 114)	NC score	0.020874 (rank : 130)
Query Neighborhood Hits	177	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q5UAW9, Q8WWB8, Q9HA73	Gene names	GPR157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

HGS_MOUSE
θ value	1.81305 (rank : 115)	NC score	0.014018 (rank : 144)
Query Neighborhood Hits	177	Target Neighborhood Hits	589	Shared Neighborhood Hits	19
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

MUC1_HUMAN
θ value	1.81305 (rank : 116)	NC score	0.020371 (rank : 132)
Query Neighborhood Hits	177	Target Neighborhood Hits	975	Shared Neighborhood Hits	39
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

TARSH_HUMAN
θ value	1.81305 (rank : 117)	NC score	0.028866 (rank : 113)
Query Neighborhood Hits	177	Target Neighborhood Hits	768	Shared Neighborhood Hits	34
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

ZAR1_MOUSE
θ value	1.81305 (rank : 118)	NC score	0.038397 (rank : 106)
Query Neighborhood Hits	177	Target Neighborhood Hits	254	Shared Neighborhood Hits	20
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

ASTL_HUMAN
θ value	2.36792 (rank : 119)	NC score	0.020996 (rank : 127)
Query Neighborhood Hits	177	Target Neighborhood Hits	252	Shared Neighborhood Hits	18
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

EDN3_HUMAN
θ value	2.36792 (rank : 120)	NC score	0.023954 (rank : 123)
Query Neighborhood Hits	177	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	P14138, Q03229	Gene names	EDN3
Domain Architecture
Description	Endothelin-3 precursor (ET-3) (Preproendothelin-3) (PPET3).

HXA3_MOUSE
θ value	2.36792 (rank : 121)	NC score	0.011841 (rank : 148)
Query Neighborhood Hits	177	Target Neighborhood Hits	558	Shared Neighborhood Hits	27
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

HXA4_HUMAN
θ value	2.36792 (rank : 122)	NC score	0.004093 (rank : 171)
Query Neighborhood Hits	177	Target Neighborhood Hits	370	Shared Neighborhood Hits	13
SwissProt Accessions	Q00056, O43366	Gene names	HOXA4, HOX1D
Domain Architecture
Description	Homeobox protein Hox-A4 (Hox-1D) (Hox-1.4).

JPH2_MOUSE
θ value	2.36792 (rank : 123)	NC score	0.026262 (rank : 117)
Query Neighborhood Hits	177	Target Neighborhood Hits	279	Shared Neighborhood Hits	32
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

MY18B_HUMAN
θ value	2.36792 (rank : 124)	NC score	0.008924 (rank : 156)
Query Neighborhood Hits	177	Target Neighborhood Hits	1299	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYH14_MOUSE
θ value	2.36792 (rank : 125)	NC score	0.002287 (rank : 173)
Query Neighborhood Hits	177	Target Neighborhood Hits	1225	Shared Neighborhood Hits	14
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

PDXL2_HUMAN
θ value	2.36792 (rank : 126)	NC score	0.021445 (rank : 125)
Query Neighborhood Hits	177	Target Neighborhood Hits	75	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NZ53, Q6UVY4, Q8WUV6	Gene names	PODXL2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

SNX15_HUMAN
θ value	2.36792 (rank : 127)	NC score	0.017431 (rank : 134)
Query Neighborhood Hits	177	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NRS6, Q9NRS5	Gene names	SNX15
Domain Architecture
Description	Sorting nexin-15.

ACHA4_HUMAN
θ value	3.0926 (rank : 128)	NC score	0.005013 (rank : 166)
Query Neighborhood Hits	177	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	P43681, Q4JGR7	Gene names	CHRNA4, NACRA4
Domain Architecture
Description	Neuronal acetylcholine receptor protein subunit alpha-4 precursor.

ACOT3_MOUSE
θ value	3.0926 (rank : 129)	NC score	0.008777 (rank : 157)
Query Neighborhood Hits	177	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QYR7, Q6Q2Z7	Gene names	Acot3, Pte1a, Pte2, Pte2a
Domain Architecture
Description	Acyl-coenzyme A thioesterase 3 (EC 3.1.2.2) (Acyl-CoA thioesterase 3) (Peroxisomal acyl-coenzyme A thioester hydrolase 2a) (Peroxisomal long-chain acyl-coA thioesterase 2) (PTE-Ia).

BSN_HUMAN
θ value	3.0926 (rank : 130)	NC score	0.036190 (rank : 109)
Query Neighborhood Hits	177	Target Neighborhood Hits	1537	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CF015_HUMAN
θ value	3.0926 (rank : 131)	NC score	0.028119 (rank : 115)
Query Neighborhood Hits	177	Target Neighborhood Hits	60	Shared Neighborhood Hits	7
SwissProt Accessions	Q6UXA7, Q5SQ81, Q86Z05, Q9UIG3	Gene names	C6orf15, STG
Domain Architecture	No domain graphic available
Description	Protein C6orf15 precursor (Protein STG).

JADE2_MOUSE
θ value	3.0926 (rank : 132)	NC score	0.014805 (rank : 141)
Query Neighborhood Hits	177	Target Neighborhood Hits	560	Shared Neighborhood Hits	27
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

PHLB1_HUMAN
θ value	3.0926 (rank : 133)	NC score	0.015035 (rank : 140)
Query Neighborhood Hits	177	Target Neighborhood Hits	1038	Shared Neighborhood Hits	30
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

SRRM2_HUMAN
θ value	3.0926 (rank : 134)	NC score	0.033064 (rank : 110)
Query Neighborhood Hits	177	Target Neighborhood Hits	1296	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

K1802_HUMAN
θ value	4.03905 (rank : 135)	NC score	0.020423 (rank : 131)
Query Neighborhood Hits	177	Target Neighborhood Hits	1378	Shared Neighborhood Hits	40
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MARCS_MOUSE
θ value	4.03905 (rank : 136)	NC score	0.054732 (rank : 99)
Query Neighborhood Hits	177	Target Neighborhood Hits	227	Shared Neighborhood Hits	25
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

PCLO_MOUSE
θ value	4.03905 (rank : 137)	NC score	0.024631 (rank : 122)
Query Neighborhood Hits	177	Target Neighborhood Hits	2275	Shared Neighborhood Hits	68
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RP1L1_MOUSE
θ value	4.03905 (rank : 138)	NC score	0.027095 (rank : 116)
Query Neighborhood Hits	177	Target Neighborhood Hits	170	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

SELPL_MOUSE
θ value	4.03905 (rank : 139)	NC score	0.025491 (rank : 119)
Query Neighborhood Hits	177	Target Neighborhood Hits	588	Shared Neighborhood Hits	29
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SYN3_MOUSE
θ value	4.03905 (rank : 140)	NC score	0.043989 (rank : 103)
Query Neighborhood Hits	177	Target Neighborhood Hits	200	Shared Neighborhood Hits	24
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

WWP2_MOUSE
θ value	4.03905 (rank : 141)	NC score	0.004127 (rank : 170)
Query Neighborhood Hits	177	Target Neighborhood Hits	118	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

ASPP2_HUMAN
θ value	5.27518 (rank : 142)	NC score	0.004983 (rank : 167)
Query Neighborhood Hits	177	Target Neighborhood Hits	1156	Shared Neighborhood Hits	25
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ATS7_HUMAN
θ value	5.27518 (rank : 143)	NC score	0.004257 (rank : 169)
Query Neighborhood Hits	177	Target Neighborhood Hits	169	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

DUX4_HUMAN
θ value	5.27518 (rank : 144)	NC score	0.006003 (rank : 164)
Query Neighborhood Hits	177	Target Neighborhood Hits	403	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UBX2	Gene names	DUX4, DUX10
Domain Architecture	No domain graphic available
Description	Double homeobox protein 4 (Double homeobox protein 10) (Double homeobox protein 4/10).

MAST1_MOUSE
θ value	5.27518 (rank : 145)	NC score	-0.002506 (rank : 179)
Query Neighborhood Hits	177	Target Neighborhood Hits	1123	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MBB1A_HUMAN
θ value	5.27518 (rank : 146)	NC score	0.025843 (rank : 118)
Query Neighborhood Hits	177	Target Neighborhood Hits	665	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MYH14_HUMAN
θ value	5.27518 (rank : 147)	NC score	0.001747 (rank : 174)
Query Neighborhood Hits	177	Target Neighborhood Hits	995	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

PHLB1_MOUSE
θ value	5.27518 (rank : 148)	NC score	0.014109 (rank : 143)
Query Neighborhood Hits	177	Target Neighborhood Hits	678	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

SYNPO_MOUSE
θ value	5.27518 (rank : 149)	NC score	0.016810 (rank : 136)
Query Neighborhood Hits	177	Target Neighborhood Hits	242	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

APC_HUMAN
θ value	6.88961 (rank : 150)	NC score	0.015247 (rank : 139)
Query Neighborhood Hits	177	Target Neighborhood Hits	603	Shared Neighborhood Hits	26
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

CD2_HUMAN
θ value	6.88961 (rank : 151)	NC score	0.016414 (rank : 137)
Query Neighborhood Hits	177	Target Neighborhood Hits	504	Shared Neighborhood Hits	17
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CGRE1_HUMAN
θ value	6.88961 (rank : 152)	NC score	0.021710 (rank : 124)
Query Neighborhood Hits	177	Target Neighborhood Hits	354	Shared Neighborhood Hits	16
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

CLIC6_MOUSE
θ value	6.88961 (rank : 153)	NC score	0.011116 (rank : 150)
Query Neighborhood Hits	177	Target Neighborhood Hits	134	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BHB9	Gene names	Clic6
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

CO5A2_HUMAN
θ value	6.88961 (rank : 154)	NC score	0.009329 (rank : 155)
Query Neighborhood Hits	177	Target Neighborhood Hits	760	Shared Neighborhood Hits	29
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CSTFT_MOUSE
θ value	6.88961 (rank : 155)	NC score	0.009597 (rank : 154)
Query Neighborhood Hits	177	Target Neighborhood Hits	356	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C7E9, Q6A016, Q8BHH7, Q8C3W7, Q8R2Y1, Q9EPU3	Gene names	Cstf2t, Kiaa0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

F19A3_MOUSE
θ value	6.88961 (rank : 156)	NC score	0.007936 (rank : 160)
Query Neighborhood Hits	177	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TPG6	Gene names	Fam19a3, Tafa3
Domain Architecture	No domain graphic available
Description	Protein FAM19A3 precursor (Chemokine-like protein TAFA-3).

GLI2_HUMAN
θ value	6.88961 (rank : 157)	NC score	-0.002723 (rank : 181)
Query Neighborhood Hits	177	Target Neighborhood Hits	971	Shared Neighborhood Hits	25
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

K0323_HUMAN
θ value	6.88961 (rank : 158)	NC score	0.020980 (rank : 128)
Query Neighborhood Hits	177	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	O15037, Q86TZ6, Q8IUQ2, Q96BA9	Gene names	KIAA0323
Domain Architecture	No domain graphic available
Description	Protein KIAA0323.

KCNH2_HUMAN
θ value	6.88961 (rank : 159)	NC score	0.004601 (rank : 168)
Query Neighborhood Hits	177	Target Neighborhood Hits	158	Shared Neighborhood Hits	10
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KSR1_HUMAN
θ value	6.88961 (rank : 160)	NC score	-0.002404 (rank : 178)
Query Neighborhood Hits	177	Target Neighborhood Hits	867	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

NUCKS_HUMAN
θ value	6.88961 (rank : 161)	NC score	0.013779 (rank : 145)
Query Neighborhood Hits	177	Target Neighborhood Hits	143	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

ZIM10_HUMAN
θ value	6.88961 (rank : 162)	NC score	0.020327 (rank : 133)
Query Neighborhood Hits	177	Target Neighborhood Hits	577	Shared Neighborhood Hits	25
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZN333_HUMAN
θ value	6.88961 (rank : 163)	NC score	-0.005475 (rank : 183)
Query Neighborhood Hits	177	Target Neighborhood Hits	750	Shared Neighborhood Hits	6
SwissProt Accessions	Q96JL9, Q8TDL0	Gene names	ZNF333, KIAA1806
Domain Architecture
Description	Zinc finger protein 333.

AAK1_HUMAN
θ value	8.99809 (rank : 164)	NC score	0.001674 (rank : 175)
Query Neighborhood Hits	177	Target Neighborhood Hits	1077	Shared Neighborhood Hits	31
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

BACH1_MOUSE
θ value	8.99809 (rank : 165)	NC score	0.000629 (rank : 176)
Query Neighborhood Hits	177	Target Neighborhood Hits	289	Shared Neighborhood Hits	3
SwissProt Accessions	P97302	Gene names	Bach1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1).

CAD16_MOUSE
θ value	8.99809 (rank : 166)	NC score	0.000113 (rank : 177)
Query Neighborhood Hits	177	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	O88338, Q9JLZ5	Gene names	Cdh16
Domain Architecture
Description	Cadherin-16 precursor (Kidney-specific cadherin) (Ksp-cadherin).

COIA1_MOUSE
θ value	8.99809 (rank : 167)	NC score	0.016272 (rank : 138)
Query Neighborhood Hits	177	Target Neighborhood Hits	481	Shared Neighborhood Hits	28
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

EMID1_HUMAN
θ value	8.99809 (rank : 168)	NC score	0.010484 (rank : 151)
Query Neighborhood Hits	177	Target Neighborhood Hits	215	Shared Neighborhood Hits	17
SwissProt Accessions	Q96A84, Q6ICG1, Q86SS7	Gene names	EMID1, EMU1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

FATH_HUMAN
θ value	8.99809 (rank : 169)	NC score	-0.002709 (rank : 180)
Query Neighborhood Hits	177	Target Neighborhood Hits	570	Shared Neighborhood Hits	4
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

JIP1_HUMAN
θ value	8.99809 (rank : 170)	NC score	0.010229 (rank : 152)
Query Neighborhood Hits	177	Target Neighborhood Hits	271	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

MYST3_MOUSE
θ value	8.99809 (rank : 171)	NC score	0.012641 (rank : 147)
Query Neighborhood Hits	177	Target Neighborhood Hits	688	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

PSL1_HUMAN
θ value	8.99809 (rank : 172)	NC score	0.014260 (rank : 142)
Query Neighborhood Hits	177	Target Neighborhood Hits	650	Shared Neighborhood Hits	29
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RGS3_HUMAN
θ value	8.99809 (rank : 173)	NC score	0.011720 (rank : 149)
Query Neighborhood Hits	177	Target Neighborhood Hits	1375	Shared Neighborhood Hits	51
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RNF12_HUMAN
θ value	8.99809 (rank : 174)	NC score	0.005199 (rank : 165)
Query Neighborhood Hits	177	Target Neighborhood Hits	173	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

TNIK_HUMAN
θ value	8.99809 (rank : 175)	NC score	-0.003929 (rank : 182)
Query Neighborhood Hits	177	Target Neighborhood Hits	1570	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

YLPM1_HUMAN
θ value	8.99809 (rank : 176)	NC score	0.044864 (rank : 102)
Query Neighborhood Hits	177	Target Neighborhood Hits	670	Shared Neighborhood Hits	39
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ZFP28_HUMAN
θ value	8.99809 (rank : 177)	NC score	-0.005623 (rank : 184)
Query Neighborhood Hits	177	Target Neighborhood Hits	843	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NHY6, Q9BY30, Q9P2B6	Gene names	ZFP28, KIAA1431
Domain Architecture
Description	Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6).

CC026_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.090387 (rank : 93)
Query Neighborhood Hits	177	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

CC026_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.063571 (rank : 96)
Query Neighborhood Hits	177	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

DDX58_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.142028 (rank : 89)
Query Neighborhood Hits	177	Target Neighborhood Hits	105	Shared Neighborhood Hits	56
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DDX58_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.158452 (rank : 88)
Query Neighborhood Hits	177	Target Neighborhood Hits	99	Shared Neighborhood Hits	59
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

EXDL2_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.058690 (rank : 97)
Query Neighborhood Hits	177	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVH0, Q8N3D3	Gene names	EXDL2, C14orf114
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.

EXDL2_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.056541 (rank : 98)
Query Neighborhood Hits	177	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VEG4	Gene names	Exdl2
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.

PRB3_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.052198 (rank : 100)
Query Neighborhood Hits	177	Target Neighborhood Hits	318	Shared Neighborhood Hits	32
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

Hits sorted by NC score

RECQ4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	177	Target Neighborhood Hits	177	Shared Neighborhood Hits	177
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RECQ4_MOUSE
NC score	0.966352 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	177	Target Neighborhood Hits	206	Shared Neighborhood Hits	94
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

RECQ1_HUMAN
NC score	0.838152 (rank : 3)	θ value	4.2656e-42 (rank : 4)
Query Neighborhood Hits	177	Target Neighborhood Hits	100	Shared Neighborhood Hits	78
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ1_MOUSE
NC score	0.837816 (rank : 4)	θ value	4.2656e-42 (rank : 5)
Query Neighborhood Hits	177	Target Neighborhood Hits	95	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

BLM_MOUSE
NC score	0.823777 (rank : 5)	θ value	1.62093e-41 (rank : 7)
Query Neighborhood Hits	177	Target Neighborhood Hits	108	Shared Neighborhood Hits	73
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

BLM_HUMAN
NC score	0.817840 (rank : 6)	θ value	2.11701e-41 (rank : 8)
Query Neighborhood Hits	177	Target Neighborhood Hits	148	Shared Neighborhood Hits	75
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

RECQ5_HUMAN
NC score	0.813979 (rank : 7)	θ value	4.86918e-46 (rank : 3)
Query Neighborhood Hits	177	Target Neighborhood Hits	390	Shared Neighborhood Hits	98
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

WRN_HUMAN
NC score	0.808735 (rank : 8)	θ value	3.61106e-41 (rank : 9)
Query Neighborhood Hits	177	Target Neighborhood Hits	132	Shared Neighborhood Hits	83
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

WRN_MOUSE
NC score	0.788967 (rank : 9)	θ value	7.27602e-42 (rank : 6)
Query Neighborhood Hits	177	Target Neighborhood Hits	295	Shared Neighborhood Hits	82
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

DDX17_HUMAN
NC score	0.606060 (rank : 10)	θ value	1.63604e-09 (rank : 15)
Query Neighborhood Hits	177	Target Neighborhood Hits	104	Shared Neighborhood Hits	87
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX17_MOUSE
NC score	0.605918 (rank : 11)	θ value	1.63604e-09 (rank : 16)
Query Neighborhood Hits	177	Target Neighborhood Hits	105	Shared Neighborhood Hits	85
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX5_MOUSE
NC score	0.605845 (rank : 12)	θ value	9.59137e-10 (rank : 14)
Query Neighborhood Hits	177	Target Neighborhood Hits	101	Shared Neighborhood Hits	85
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX5_HUMAN
NC score	0.605772 (rank : 13)	θ value	7.34386e-10 (rank : 13)
Query Neighborhood Hits	177	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX43_HUMAN
NC score	0.601679 (rank : 14)	θ value	1.33837e-11 (rank : 10)
Query Neighborhood Hits	177	Target Neighborhood Hits	120	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX46_HUMAN
NC score	0.596210 (rank : 15)	θ value	1.133e-10 (rank : 11)
Query Neighborhood Hits	177	Target Neighborhood Hits	357	Shared Neighborhood Hits	92
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
NC score	0.595265 (rank : 16)	θ value	1.133e-10 (rank : 12)
Query Neighborhood Hits	177	Target Neighborhood Hits	358	Shared Neighborhood Hits	94
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX41_HUMAN
NC score	0.587135 (rank : 17)	θ value	1.80886e-08 (rank : 18)
Query Neighborhood Hits	177	Target Neighborhood Hits	111	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX50_HUMAN
NC score	0.587027 (rank : 18)	θ value	3.08544e-08 (rank : 19)
Query Neighborhood Hits	177	Target Neighborhood Hits	132	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_MOUSE
NC score	0.586439 (rank : 19)	θ value	3.08544e-08 (rank : 20)
Query Neighborhood Hits	177	Target Neighborhood Hits	137	Shared Neighborhood Hits	86
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX41_MOUSE
NC score	0.584967 (rank : 20)	θ value	5.26297e-08 (rank : 22)
Query Neighborhood Hits	177	Target Neighborhood Hits	115	Shared Neighborhood Hits	86
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX6_HUMAN
NC score	0.580553 (rank : 21)	θ value	1.29631e-06 (rank : 30)
Query Neighborhood Hits	177	Target Neighborhood Hits	97	Shared Neighborhood Hits	89
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
NC score	0.580342 (rank : 22)	θ value	1.29631e-06 (rank : 31)
Query Neighborhood Hits	177	Target Neighborhood Hits	98	Shared Neighborhood Hits	89
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX21_HUMAN
NC score	0.575052 (rank : 23)	θ value	2.61198e-07 (rank : 28)
Query Neighborhood Hits	177	Target Neighborhood Hits	308	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX52_HUMAN
NC score	0.574000 (rank : 24)	θ value	1.43324e-05 (rank : 45)
Query Neighborhood Hits	177	Target Neighborhood Hits	107	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX53_HUMAN
NC score	0.573055 (rank : 25)	θ value	5.26297e-08 (rank : 26)
Query Neighborhood Hits	177	Target Neighborhood Hits	124	Shared Neighborhood Hits	82
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX49_MOUSE
NC score	0.571957 (rank : 26)	θ value	4.0297e-08 (rank : 21)
Query Neighborhood Hits	177	Target Neighborhood Hits	119	Shared Neighborhood Hits	87
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX48_HUMAN
NC score	0.571252 (rank : 27)	θ value	5.26297e-08 (rank : 23)
Query Neighborhood Hits	177	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
NC score	0.571043 (rank : 28)	θ value	5.26297e-08 (rank : 24)
Query Neighborhood Hits	177	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX52_MOUSE
NC score	0.570189 (rank : 29)	θ value	0.00134147 (rank : 56)
Query Neighborhood Hits	177	Target Neighborhood Hits	101	Shared Neighborhood Hits	87
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX49_HUMAN
NC score	0.570171 (rank : 30)	θ value	4.76016e-09 (rank : 17)
Query Neighborhood Hits	177	Target Neighborhood Hits	223	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX21_MOUSE
NC score	0.569575 (rank : 31)	θ value	1.17247e-07 (rank : 27)
Query Neighborhood Hits	177	Target Neighborhood Hits	350	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX3X_MOUSE
NC score	0.564949 (rank : 32)	θ value	3.19293e-05 (rank : 48)
Query Neighborhood Hits	177	Target Neighborhood Hits	117	Shared Neighborhood Hits	85
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX3Y_HUMAN
NC score	0.564319 (rank : 33)	θ value	1.43324e-05 (rank : 44)
Query Neighborhood Hits	177	Target Neighborhood Hits	121	Shared Neighborhood Hits	85
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX3X_HUMAN
NC score	0.564032 (rank : 34)	θ value	3.19293e-05 (rank : 47)
Query Neighborhood Hits	177	Target Neighborhood Hits	122	Shared Neighborhood Hits	85
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX47_MOUSE
NC score	0.563965 (rank : 35)	θ value	2.21117e-06 (rank : 35)
Query Neighborhood Hits	177	Target Neighborhood Hits	97	Shared Neighborhood Hits	85
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_HUMAN
NC score	0.563791 (rank : 36)	θ value	2.21117e-06 (rank : 34)
Query Neighborhood Hits	177	Target Neighborhood Hits	97	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

PL10_MOUSE
NC score	0.563092 (rank : 37)	θ value	3.19293e-05 (rank : 49)
Query Neighborhood Hits	177	Target Neighborhood Hits	120	Shared Neighborhood Hits	85
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX4_MOUSE
NC score	0.560609 (rank : 38)	θ value	5.26297e-08 (rank : 25)
Query Neighborhood Hits	177	Target Neighborhood Hits	100	Shared Neighborhood Hits	87
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX3Y_MOUSE
NC score	0.560233 (rank : 39)	θ value	7.1131e-05 (rank : 50)
Query Neighborhood Hits	177	Target Neighborhood Hits	126	Shared Neighborhood Hits	86
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

IF4A2_HUMAN
NC score	0.559545 (rank : 40)	θ value	1.29631e-06 (rank : 32)
Query Neighborhood Hits	177	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
NC score	0.559545 (rank : 41)	θ value	1.29631e-06 (rank : 33)
Query Neighborhood Hits	177	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX4_HUMAN
NC score	0.559412 (rank : 42)	θ value	7.59969e-07 (rank : 29)
Query Neighborhood Hits	177	Target Neighborhood Hits	123	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

IF4A1_HUMAN
NC score	0.557783 (rank : 43)	θ value	2.21117e-06 (rank : 36)
Query Neighborhood Hits	177	Target Neighborhood Hits	106	Shared Neighborhood Hits	85
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
NC score	0.557783 (rank : 44)	θ value	2.21117e-06 (rank : 37)
Query Neighborhood Hits	177	Target Neighborhood Hits	106	Shared Neighborhood Hits	85
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

DDX27_MOUSE
NC score	0.555652 (rank : 45)	θ value	0.00035302 (rank : 52)
Query Neighborhood Hits	177	Target Neighborhood Hits	174	Shared Neighborhood Hits	85
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX39_HUMAN
NC score	0.555389 (rank : 46)	θ value	8.40245e-06 (rank : 39)
Query Neighborhood Hits	177	Target Neighborhood Hits	94	Shared Neighborhood Hits	85
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX23_HUMAN
NC score	0.554833 (rank : 47)	θ value	0.00390308 (rank : 60)
Query Neighborhood Hits	177	Target Neighborhood Hits	486	Shared Neighborhood Hits	90
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX27_HUMAN
NC score	0.554214 (rank : 48)	θ value	0.000158464 (rank : 51)
Query Neighborhood Hits	177	Target Neighborhood Hits	197	Shared Neighborhood Hits	85
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX39_MOUSE
NC score	0.553913 (rank : 49)	θ value	6.43352e-06 (rank : 38)
Query Neighborhood Hits	177	Target Neighborhood Hits	97	Shared Neighborhood Hits	85
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

UAP56_HUMAN
NC score	0.547523 (rank : 50)	θ value	8.40245e-06 (rank : 40)
Query Neighborhood Hits	177	Target Neighborhood Hits	96	Shared Neighborhood Hits	85
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

DDX31_HUMAN
NC score	0.547497 (rank : 51)	θ value	1.43324e-05 (rank : 43)
Query Neighborhood Hits	177	Target Neighborhood Hits	132	Shared Neighborhood Hits	89
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

UAP56_MOUSE
NC score	0.547444 (rank : 52)	θ value	8.40245e-06 (rank : 41)
Query Neighborhood Hits	177	Target Neighborhood Hits	96	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX51_HUMAN
NC score	0.536650 (rank : 53)	θ value	1.09739e-05 (rank : 42)
Query Neighborhood Hits	177	Target Neighborhood Hits	332	Shared Neighborhood Hits	98
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX51_MOUSE
NC score	0.535115 (rank : 54)	θ value	2.44474e-05 (rank : 46)
Query Neighborhood Hits	177	Target Neighborhood Hits	130	Shared Neighborhood Hits	89
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX54_MOUSE
NC score	0.530757 (rank : 55)	θ value	0.163984 (rank : 85)
Query Neighborhood Hits	177	Target Neighborhood Hits	124	Shared Neighborhood Hits	88
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX54_HUMAN
NC score	0.530729 (rank : 56)	θ value	0.0148317 (rank : 73)
Query Neighborhood Hits	177	Target Neighborhood Hits	170	Shared Neighborhood Hits	89
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX28_MOUSE
NC score	0.529498 (rank : 57)	θ value	0.00509761 (rank : 62)
Query Neighborhood Hits	177	Target Neighborhood Hits	112	Shared Neighborhood Hits	87
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX24_MOUSE
NC score	0.529358 (rank : 58)	θ value	0.00869519 (rank : 68)
Query Neighborhood Hits	177	Target Neighborhood Hits	147	Shared Neighborhood Hits	87
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX24_HUMAN
NC score	0.526881 (rank : 59)	θ value	0.0193708 (rank : 74)
Query Neighborhood Hits	177	Target Neighborhood Hits	190	Shared Neighborhood Hits	87
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX10_HUMAN
NC score	0.525703 (rank : 60)	θ value	0.0148317 (rank : 72)
Query Neighborhood Hits	177	Target Neighborhood Hits	210	Shared Neighborhood Hits	84
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX10_MOUSE
NC score	0.524994 (rank : 61)	θ value	0.00869519 (rank : 65)
Query Neighborhood Hits	177	Target Neighborhood Hits	233	Shared Neighborhood Hits	85
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX1_MOUSE
NC score	0.520915 (rank : 62)	θ value	0.00228821 (rank : 59)
Query Neighborhood Hits	177	Target Neighborhood Hits	112	Shared Neighborhood Hits	83
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX20_HUMAN
NC score	0.520227 (rank : 63)	θ value	0.00869519 (rank : 67)
Query Neighborhood Hits	177	Target Neighborhood Hits	121	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX1_HUMAN
NC score	0.519520 (rank : 64)	θ value	0.00134147 (rank : 55)
Query Neighborhood Hits	177	Target Neighborhood Hits	110	Shared Neighborhood Hits	83
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX20_MOUSE
NC score	0.517453 (rank : 65)	θ value	0.00665767 (rank : 64)
Query Neighborhood Hits	177	Target Neighborhood Hits	177	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX18_HUMAN
NC score	0.512171 (rank : 66)	θ value	0.00869519 (rank : 66)
Query Neighborhood Hits	177	Target Neighborhood Hits	124	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX18_MOUSE
NC score	0.510291 (rank : 67)	θ value	0.000461057 (rank : 53)
Query Neighborhood Hits	177	Target Neighborhood Hits	115	Shared Neighborhood Hits	82
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX28_HUMAN
NC score	0.509645 (rank : 68)	θ value	0.21417 (rank : 88)
Query Neighborhood Hits	177	Target Neighborhood Hits	103	Shared Neighborhood Hits	82
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX55_MOUSE
NC score	0.505720 (rank : 69)	θ value	0.0252991 (rank : 77)
Query Neighborhood Hits	177	Target Neighborhood Hits	111	Shared Neighborhood Hits	85
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DD19A_HUMAN
NC score	0.504140 (rank : 70)	θ value	0.0148317 (rank : 70)
Query Neighborhood Hits	177	Target Neighborhood Hits	107	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DDX55_HUMAN
NC score	0.503655 (rank : 71)	θ value	0.0252991 (rank : 76)
Query Neighborhood Hits	177	Target Neighborhood Hits	122	Shared Neighborhood Hits	83
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DD19A_MOUSE
NC score	0.503592 (rank : 72)	θ value	0.0113563 (rank : 69)
Query Neighborhood Hits	177	Target Neighborhood Hits	105	Shared Neighborhood Hits	83
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DD19B_HUMAN
NC score	0.503574 (rank : 73)	θ value	0.0148317 (rank : 71)
Query Neighborhood Hits	177	Target Neighborhood Hits	109	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DDX25_HUMAN
NC score	0.503552 (rank : 74)	θ value	0.0330416 (rank : 79)
Query Neighborhood Hits	177	Target Neighborhood Hits	93	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX25_MOUSE
NC score	0.501344 (rank : 75)	θ value	0.0330416 (rank : 80)
Query Neighborhood Hits	177	Target Neighborhood Hits	98	Shared Neighborhood Hits	81
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX56_MOUSE
NC score	0.486970 (rank : 76)	θ value	0.125558 (rank : 83)
Query Neighborhood Hits	177	Target Neighborhood Hits	87	Shared Neighborhood Hits	74
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX56_HUMAN
NC score	0.485039 (rank : 77)	θ value	0.279714 (rank : 93)
Query Neighborhood Hits	177	Target Neighborhood Hits	77	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DICER_MOUSE
NC score	0.292864 (rank : 78)	θ value	0.0193708 (rank : 75)
Query Neighborhood Hits	177	Target Neighborhood Hits	140	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

DICER_HUMAN
NC score	0.290835 (rank : 79)	θ value	0.0252991 (rank : 78)
Query Neighborhood Hits	177	Target Neighborhood Hits	126	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

LGP2_HUMAN
NC score	0.280212 (rank : 80)	θ value	0.00134147 (rank : 57)
Query Neighborhood Hits	177	Target Neighborhood Hits	94	Shared Neighborhood Hits	73
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

LGP2_MOUSE
NC score	0.278917 (rank : 81)	θ value	0.000786445 (rank : 54)
Query Neighborhood Hits	177	Target Neighborhood Hits	86	Shared Neighborhood Hits	70
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

FANCM_HUMAN
NC score	0.278510 (rank : 82)	θ value	0.163984 (rank : 86)
Query Neighborhood Hits	177	Target Neighborhood Hits	210	Shared Neighborhood Hits	80
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

FANCM_MOUSE
NC score	0.275284 (rank : 83)	θ value	0.813845 (rank : 102)
Query Neighborhood Hits	177	Target Neighborhood Hits	177	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

IFIH1_HUMAN
NC score	0.263049 (rank : 84)	θ value	0.21417 (rank : 89)
Query Neighborhood Hits	177	Target Neighborhood Hits	96	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

IFIH1_MOUSE
NC score	0.255645 (rank : 85)	θ value	0.21417 (rank : 90)
Query Neighborhood Hits	177	Target Neighborhood Hits	126	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

U520_HUMAN
NC score	0.204930 (rank : 86)	θ value	0.47712 (rank : 100)
Query Neighborhood Hits	177	Target Neighborhood Hits	88	Shared Neighborhood Hits	47
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

HELC1_HUMAN
NC score	0.193692 (rank : 87)	θ value	0.00509761 (rank : 63)
Query Neighborhood Hits	177	Target Neighborhood Hits	71	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

DDX58_MOUSE
NC score	0.158452 (rank : 88)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	177	Target Neighborhood Hits	99	Shared Neighborhood Hits	59
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DDX58_HUMAN
NC score	0.142028 (rank : 89)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	177	Target Neighborhood Hits	105	Shared Neighborhood Hits	56
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

SKIV2_HUMAN
NC score	0.118705 (rank : 90)	θ value	0.279714 (rank : 94)
Query Neighborhood Hits	177	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	Q15477, O15005, Q12902, Q15476	Gene names	SKIV2L, DDX13, SKI2W, SKIV2, W
Domain Architecture
Description	Helicase SKI2W (EC 3.6.1.-) (Helicase-like protein) (HLP).

SK2L2_HUMAN
NC score	0.102453 (rank : 91)	θ value	0.365318 (rank : 96)
Query Neighborhood Hits	177	Target Neighborhood Hits	36	Shared Neighborhood Hits	17
SwissProt Accessions	P42285, Q8TAG2	Gene names	SKIV2L2, KIAA0052
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SK2L2_MOUSE
NC score	0.101174 (rank : 92)	θ value	0.365318 (rank : 97)
Query Neighborhood Hits	177	Target Neighborhood Hits	45	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CZU3	Gene names	Skiv2l2
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

CC026_HUMAN
NC score	0.090387 (rank : 93)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	177	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

SYN1_HUMAN
NC score	0.075721 (rank : 94)	θ value	0.00390308 (rank : 61)
Query Neighborhood Hits	177	Target Neighborhood Hits	419	Shared Neighborhood Hits	45
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SYN1_MOUSE
NC score	0.067051 (rank : 95)	θ value	0.0431538 (rank : 82)
Query Neighborhood Hits	177	Target Neighborhood Hits	363	Shared Neighborhood Hits	41
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

CC026_MOUSE
NC score	0.063571 (rank : 96)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	177	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

EXDL2_HUMAN
NC score	0.058690 (rank : 97)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	177	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVH0, Q8N3D3	Gene names	EXDL2, C14orf114
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.

EXDL2_MOUSE
NC score	0.056541 (rank : 98)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	177	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VEG4	Gene names	Exdl2
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.

MARCS_MOUSE
NC score	0.054732 (rank : 99)	θ value	4.03905 (rank : 136)
Query Neighborhood Hits	177	Target Neighborhood Hits	227	Shared Neighborhood Hits	25
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

PRB3_HUMAN
NC score	0.052198 (rank : 100)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	177	Target Neighborhood Hits	318	Shared Neighborhood Hits	32
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

OGFR_HUMAN
NC score	0.047428 (rank : 101)	θ value	0.00134147 (rank : 58)
Query Neighborhood Hits	177	Target Neighborhood Hits	1582	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

YLPM1_HUMAN
NC score	0.044864 (rank : 102)	θ value	8.99809 (rank : 176)
Query Neighborhood Hits	177	Target Neighborhood Hits	670	Shared Neighborhood Hits	39
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

SYN3_MOUSE
NC score	0.043989 (rank : 103)	θ value	4.03905 (rank : 140)
Query Neighborhood Hits	177	Target Neighborhood Hits	200	Shared Neighborhood Hits	24
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

BAT2_HUMAN
NC score	0.043005 (rank : 104)	θ value	0.62314 (rank : 101)
Query Neighborhood Hits	177	Target Neighborhood Hits	931	Shared Neighborhood Hits	51
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

RP1L1_HUMAN
NC score	0.042723 (rank : 105)	θ value	0.21417 (rank : 92)
Query Neighborhood Hits	177	Target Neighborhood Hits	1072	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

ZAR1_MOUSE
NC score	0.038397 (rank : 106)	θ value	1.81305 (rank : 118)
Query Neighborhood Hits	177	Target Neighborhood Hits	254	Shared Neighborhood Hits	20
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

IER5_MOUSE
NC score	0.037939 (rank : 107)	θ value	1.06291 (rank : 109)
Query Neighborhood Hits	177	Target Neighborhood Hits	110	Shared Neighborhood Hits	12
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

PRRT3_HUMAN
NC score	0.037494 (rank : 108)	θ value	0.21417 (rank : 91)
Query Neighborhood Hits	177	Target Neighborhood Hits	998	Shared Neighborhood Hits	46
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

BSN_HUMAN
NC score	0.036190 (rank : 109)	θ value	3.0926 (rank : 130)
Query Neighborhood Hits	177	Target Neighborhood Hits	1537	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

SRRM2_HUMAN
NC score	0.033064 (rank : 110)	θ value	3.0926 (rank : 134)
Query Neighborhood Hits	177	Target Neighborhood Hits	1296	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

MLL3_MOUSE
NC score	0.032563 (rank : 111)	θ value	0.47712 (rank : 99)
Query Neighborhood Hits	177	Target Neighborhood Hits	1399	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLL3_HUMAN
NC score	0.031390 (rank : 112)	θ value	0.813845 (rank : 104)
Query Neighborhood Hits	177	Target Neighborhood Hits	1644	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

TARSH_HUMAN
NC score	0.028866 (rank : 113)	θ value	1.81305 (rank : 117)
Query Neighborhood Hits	177	Target Neighborhood Hits	768	Shared Neighborhood Hits	34
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

MDC1_MOUSE
NC score	0.028709 (rank : 114)	θ value	1.38821 (rank : 113)
Query Neighborhood Hits	177	Target Neighborhood Hits	998	Shared Neighborhood Hits	39
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

CF015_HUMAN
NC score	0.028119 (rank : 115)	θ value	3.0926 (rank : 131)
Query Neighborhood Hits	177	Target Neighborhood Hits	60	Shared Neighborhood Hits	7
SwissProt Accessions	Q6UXA7, Q5SQ81, Q86Z05, Q9UIG3	Gene names	C6orf15, STG
Domain Architecture	No domain graphic available
Description	Protein C6orf15 precursor (Protein STG).

RP1L1_MOUSE
NC score	0.027095 (rank : 116)	θ value	4.03905 (rank : 138)
Query Neighborhood Hits	177	Target Neighborhood Hits	170	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

JPH2_MOUSE
NC score	0.026262 (rank : 117)	θ value	2.36792 (rank : 123)
Query Neighborhood Hits	177	Target Neighborhood Hits	279	Shared Neighborhood Hits	32
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

MBB1A_HUMAN
NC score	0.025843 (rank : 118)	θ value	5.27518 (rank : 146)
Query Neighborhood Hits	177	Target Neighborhood Hits	665	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

SELPL_MOUSE
NC score	0.025491 (rank : 119)	θ value	4.03905 (rank : 139)
Query Neighborhood Hits	177	Target Neighborhood Hits	588	Shared Neighborhood Hits	29
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

ZIM10_MOUSE
NC score	0.025454 (rank : 120)	θ value	0.813845 (rank : 105)
Query Neighborhood Hits	177	Target Neighborhood Hits	430	Shared Neighborhood Hits	27
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

K1802_MOUSE
NC score	0.025054 (rank : 121)	θ value	0.125558 (rank : 84)
Query Neighborhood Hits	177	Target Neighborhood Hits	1596	Shared Neighborhood Hits	46
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

PCLO_MOUSE
NC score	0.024631 (rank : 122)	θ value	4.03905 (rank : 137)
Query Neighborhood Hits	177	Target Neighborhood Hits	2275	Shared Neighborhood Hits	68
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

EDN3_HUMAN
NC score	0.023954 (rank : 123)	θ value	2.36792 (rank : 120)
Query Neighborhood Hits	177	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	P14138, Q03229	Gene names	EDN3
Domain Architecture
Description	Endothelin-3 precursor (ET-3) (Preproendothelin-3) (PPET3).

CGRE1_HUMAN
NC score	0.021710 (rank : 124)	θ value	6.88961 (rank : 152)
Query Neighborhood Hits	177	Target Neighborhood Hits	354	Shared Neighborhood Hits	16
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

PDXL2_HUMAN
NC score	0.021445 (rank : 125)	θ value	2.36792 (rank : 126)
Query Neighborhood Hits	177	Target Neighborhood Hits	75	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NZ53, Q6UVY4, Q8WUV6	Gene names	PODXL2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

ARMX2_MOUSE
NC score	0.021273 (rank : 126)	θ value	1.38821 (rank : 111)
Query Neighborhood Hits	177	Target Neighborhood Hits	349	Shared Neighborhood Hits	23
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

ASTL_HUMAN
NC score	0.020996 (rank : 127)	θ value	2.36792 (rank : 119)
Query Neighborhood Hits	177	Target Neighborhood Hits	252	Shared Neighborhood Hits	18
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

K0323_HUMAN
NC score	0.020980 (rank : 128)	θ value	6.88961 (rank : 158)
Query Neighborhood Hits	177	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	O15037, Q86TZ6, Q8IUQ2, Q96BA9	Gene names	KIAA0323
Domain Architecture	No domain graphic available
Description	Protein KIAA0323.

COIA1_HUMAN
NC score	0.020979 (rank : 129)	θ value	1.06291 (rank : 107)
Query Neighborhood Hits	177	Target Neighborhood Hits	447	Shared Neighborhood Hits	28
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

GP157_HUMAN
NC score	0.020874 (rank : 130)	θ value	1.81305 (rank : 114)
Query Neighborhood Hits	177	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q5UAW9, Q8WWB8, Q9HA73	Gene names	GPR157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

K1802_HUMAN
NC score	0.020423 (rank : 131)	θ value	4.03905 (rank : 135)
Query Neighborhood Hits	177	Target Neighborhood Hits	1378	Shared Neighborhood Hits	40
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MUC1_HUMAN
NC score	0.020371 (rank : 132)	θ value	1.81305 (rank : 116)
Query Neighborhood Hits	177	Target Neighborhood Hits	975	Shared Neighborhood Hits	39
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

ZIM10_HUMAN
NC score	0.020327 (rank : 133)	θ value	6.88961 (rank : 162)
Query Neighborhood Hits	177	Target Neighborhood Hits	577	Shared Neighborhood Hits	25
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

SNX15_HUMAN
NC score	0.017431 (rank : 134)	θ value	2.36792 (rank : 127)
Query Neighborhood Hits	177	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NRS6, Q9NRS5	Gene names	SNX15
Domain Architecture
Description	Sorting nexin-15.

MAGE1_HUMAN
NC score	0.017216 (rank : 135)	θ value	1.06291 (rank : 110)
Query Neighborhood Hits	177	Target Neighborhood Hits	1389	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

SYNPO_MOUSE
NC score	0.016810 (rank : 136)	θ value	5.27518 (rank : 149)
Query Neighborhood Hits	177	Target Neighborhood Hits	242	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

CD2_HUMAN
NC score	0.016414 (rank : 137)	θ value	6.88961 (rank : 151)
Query Neighborhood Hits	177	Target Neighborhood Hits	504	Shared Neighborhood Hits	17
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

COIA1_MOUSE
NC score	0.016272 (rank : 138)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	177	Target Neighborhood Hits	481	Shared Neighborhood Hits	28
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

APC_HUMAN
NC score	0.015247 (rank : 139)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	177	Target Neighborhood Hits	603	Shared Neighborhood Hits	26
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

PHLB1_HUMAN
NC score	0.015035 (rank : 140)	θ value	3.0926 (rank : 133)
Query Neighborhood Hits	177	Target Neighborhood Hits	1038	Shared Neighborhood Hits	30
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

JADE2_MOUSE
NC score	0.014805 (rank : 141)	θ value	3.0926 (rank : 132)
Query Neighborhood Hits	177	Target Neighborhood Hits	560	Shared Neighborhood Hits	27
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

PSL1_HUMAN
NC score	0.014260 (rank : 142)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	177	Target Neighborhood Hits	650	Shared Neighborhood Hits	29
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

PHLB1_MOUSE
NC score	0.014109 (rank : 143)	θ value	5.27518 (rank : 148)
Query Neighborhood Hits	177	Target Neighborhood Hits	678	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

HGS_MOUSE
NC score	0.014018 (rank : 144)	θ value	1.81305 (rank : 115)
Query Neighborhood Hits	177	Target Neighborhood Hits	589	Shared Neighborhood Hits	19
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

NUCKS_HUMAN
NC score	0.013779 (rank : 145)	θ value	6.88961 (rank : 161)
Query Neighborhood Hits	177	Target Neighborhood Hits	143	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

CSKI2_MOUSE
NC score	0.013146 (rank : 146)	θ value	1.06291 (rank : 108)
Query Neighborhood Hits	177	Target Neighborhood Hits	812	Shared Neighborhood Hits	39
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

MYST3_MOUSE
NC score	0.012641 (rank : 147)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	177	Target Neighborhood Hits	688	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

HXA3_MOUSE
NC score	0.011841 (rank : 148)	θ value	2.36792 (rank : 121)
Query Neighborhood Hits	177	Target Neighborhood Hits	558	Shared Neighborhood Hits	27
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

RGS3_HUMAN
NC score	0.011720 (rank : 149)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	177	Target Neighborhood Hits	1375	Shared Neighborhood Hits	51
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

CLIC6_MOUSE
NC score	0.011116 (rank : 150)	θ value	6.88961 (rank : 153)
Query Neighborhood Hits	177	Target Neighborhood Hits	134	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BHB9	Gene names	Clic6
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

EMID1_HUMAN
NC score	0.010484 (rank : 151)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	177	Target Neighborhood Hits	215	Shared Neighborhood Hits	17
SwissProt Accessions	Q96A84, Q6ICG1, Q86SS7	Gene names	EMID1, EMU1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

JIP1_HUMAN
NC score	0.010229 (rank : 152)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	177	Target Neighborhood Hits	271	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

MEFV_HUMAN
NC score	0.010121 (rank : 153)	θ value	0.813845 (rank : 103)
Query Neighborhood Hits	177	Target Neighborhood Hits	431	Shared Neighborhood Hits	19
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

CSTFT_MOUSE
NC score	0.009597 (rank : 154)	θ value	6.88961 (rank : 155)
Query Neighborhood Hits	177	Target Neighborhood Hits	356	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C7E9, Q6A016, Q8BHH7, Q8C3W7, Q8R2Y1, Q9EPU3	Gene names	Cstf2t, Kiaa0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

CO5A2_HUMAN
NC score	0.009329 (rank : 155)	θ value	6.88961 (rank : 154)
Query Neighborhood Hits	177	Target Neighborhood Hits	760	Shared Neighborhood Hits	29
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

MY18B_HUMAN
NC score	0.008924 (rank : 156)	θ value	2.36792 (rank : 124)
Query Neighborhood Hits	177	Target Neighborhood Hits	1299	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

ACOT3_MOUSE
NC score	0.008777 (rank : 157)	θ value	3.0926 (rank : 129)
Query Neighborhood Hits	177	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QYR7, Q6Q2Z7	Gene names	Acot3, Pte1a, Pte2, Pte2a
Domain Architecture
Description	Acyl-coenzyme A thioesterase 3 (EC 3.1.2.2) (Acyl-CoA thioesterase 3) (Peroxisomal acyl-coenzyme A thioester hydrolase 2a) (Peroxisomal long-chain acyl-coA thioesterase 2) (PTE-Ia).

CROCC_HUMAN
NC score	0.008679 (rank : 158)	θ value	0.21417 (rank : 87)
Query Neighborhood Hits	177	Target Neighborhood Hits	1409	Shared Neighborhood Hits	23
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CAN9_MOUSE
NC score	0.008122 (rank : 159)	θ value	1.38821 (rank : 112)
Query Neighborhood Hits	177	Target Neighborhood Hits	73	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D805, O35919	Gene names	Capn9, Ncl4
Domain Architecture
Description	Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (nCL-4).

F19A3_MOUSE
NC score	0.007936 (rank : 160)	θ value	6.88961 (rank : 156)
Query Neighborhood Hits	177	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TPG6	Gene names	Fam19a3, Tafa3
Domain Architecture	No domain graphic available
Description	Protein FAM19A3 precursor (Chemokine-like protein TAFA-3).

ATS19_MOUSE
NC score	0.007690 (rank : 161)	θ value	1.06291 (rank : 106)
Query Neighborhood Hits	177	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

RTN4R_HUMAN
NC score	0.007065 (rank : 162)	θ value	0.365318 (rank : 95)
Query Neighborhood Hits	177	Target Neighborhood Hits	271	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZR6	Gene names	RTN4R, NOGOR
Domain Architecture
Description	Reticulon-4 receptor precursor (Nogo receptor) (NgR) (Nogo-66 receptor).

SPEG_MOUSE
NC score	0.006933 (rank : 163)	θ value	0.365318 (rank : 98)
Query Neighborhood Hits	177	Target Neighborhood Hits	1959	Shared Neighborhood Hits	51
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

DUX4_HUMAN
NC score	0.006003 (rank : 164)	θ value	5.27518 (rank : 144)
Query Neighborhood Hits	177	Target Neighborhood Hits	403	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UBX2	Gene names	DUX4, DUX10
Domain Architecture	No domain graphic available
Description	Double homeobox protein 4 (Double homeobox protein 10) (Double homeobox protein 4/10).

RNF12_HUMAN
NC score	0.005199 (rank : 165)	θ value	8.99809 (rank : 174)
Query Neighborhood Hits	177	Target Neighborhood Hits	173	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

ACHA4_HUMAN
NC score	0.005013 (rank : 166)	θ value	3.0926 (rank : 128)
Query Neighborhood Hits	177	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	P43681, Q4JGR7	Gene names	CHRNA4, NACRA4
Domain Architecture
Description	Neuronal acetylcholine receptor protein subunit alpha-4 precursor.

ASPP2_HUMAN
NC score	0.004983 (rank : 167)	θ value	5.27518 (rank : 142)
Query Neighborhood Hits	177	Target Neighborhood Hits	1156	Shared Neighborhood Hits	25
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

KCNH2_HUMAN
NC score	0.004601 (rank : 168)	θ value	6.88961 (rank : 159)
Query Neighborhood Hits	177	Target Neighborhood Hits	158	Shared Neighborhood Hits	10
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

ATS7_HUMAN
NC score	0.004257 (rank : 169)	θ value	5.27518 (rank : 143)
Query Neighborhood Hits	177	Target Neighborhood Hits	169	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

WWP2_MOUSE
NC score	0.004127 (rank : 170)	θ value	4.03905 (rank : 141)
Query Neighborhood Hits	177	Target Neighborhood Hits	118	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

HXA4_HUMAN
NC score	0.004093 (rank : 171)	θ value	2.36792 (rank : 122)
Query Neighborhood Hits	177	Target Neighborhood Hits	370	Shared Neighborhood Hits	13
SwissProt Accessions	Q00056, O43366	Gene names	HOXA4, HOX1D
Domain Architecture
Description	Homeobox protein Hox-A4 (Hox-1D) (Hox-1.4).

ULK1_MOUSE
NC score	0.002877 (rank : 172)	θ value	0.0330416 (rank : 81)
Query Neighborhood Hits	177	Target Neighborhood Hits	1214	Shared Neighborhood Hits	28
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

MYH14_MOUSE
NC score	0.002287 (rank : 173)	θ value	2.36792 (rank : 125)
Query Neighborhood Hits	177	Target Neighborhood Hits	1225	Shared Neighborhood Hits	14
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH14_HUMAN
NC score	0.001747 (rank : 174)	θ value	5.27518 (rank : 147)
Query Neighborhood Hits	177	Target Neighborhood Hits	995	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

AAK1_HUMAN
NC score	0.001674 (rank : 175)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	177	Target Neighborhood Hits	1077	Shared Neighborhood Hits	31
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

BACH1_MOUSE
NC score	0.000629 (rank : 176)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	177	Target Neighborhood Hits	289	Shared Neighborhood Hits	3
SwissProt Accessions	P97302	Gene names	Bach1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1).

CAD16_MOUSE
NC score	0.000113 (rank : 177)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	177	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	O88338, Q9JLZ5	Gene names	Cdh16
Domain Architecture
Description	Cadherin-16 precursor (Kidney-specific cadherin) (Ksp-cadherin).

KSR1_HUMAN
NC score	-0.002404 (rank : 178)	θ value	6.88961 (rank : 160)
Query Neighborhood Hits	177	Target Neighborhood Hits	867	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

MAST1_MOUSE
NC score	-0.002506 (rank : 179)	θ value	5.27518 (rank : 145)
Query Neighborhood Hits	177	Target Neighborhood Hits	1123	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

FATH_HUMAN
NC score	-0.002709 (rank : 180)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	177	Target Neighborhood Hits	570	Shared Neighborhood Hits	4
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

GLI2_HUMAN
NC score	-0.002723 (rank : 181)	θ value	6.88961 (rank : 157)
Query Neighborhood Hits	177	Target Neighborhood Hits	971	Shared Neighborhood Hits	25
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

TNIK_HUMAN
NC score	-0.003929 (rank : 182)	θ value	8.99809 (rank : 175)
Query Neighborhood Hits	177	Target Neighborhood Hits	1570	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

ZN333_HUMAN
NC score	-0.005475 (rank : 183)	θ value	6.88961 (rank : 163)
Query Neighborhood Hits	177	Target Neighborhood Hits	750	Shared Neighborhood Hits	6
SwissProt Accessions	Q96JL9, Q8TDL0	Gene names	ZNF333, KIAA1806
Domain Architecture
Description	Zinc finger protein 333.

ZFP28_HUMAN
NC score	-0.005623 (rank : 184)	θ value	8.99809 (rank : 177)
Query Neighborhood Hits	177	Target Neighborhood Hits	843	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NHY6, Q9BY30, Q9P2B6	Gene names	ZFP28, KIAA1431
Domain Architecture
Description	Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6).