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Network neighborhood for query Sequence : EXDL2_HUMAN

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EXDL2_HUMAN
SwissProt Accessions	Q9NVH0, Q8N3D3	Gene names	EXDL2, C14orf114
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EXDL2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NVH0, Q8N3D3	Gene names	EXDL2, C14orf114
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.

EXDL2_MOUSE
θ value	0 (rank : 2)	NC score	0.996734 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VEG4	Gene names	Exdl2
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.

WRN_HUMAN
θ value	3.64472e-09 (rank : 3)	NC score	0.254095 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	132	Shared Neighborhood Hits	4
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

WRN_MOUSE
θ value	1.38499e-08 (rank : 4)	NC score	0.241808 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	295	Shared Neighborhood Hits	4
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

K0562_MOUSE
θ value	0.62314 (rank : 5)	NC score	0.046253 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	Q80V31, Q6ZQ95	Gene names	Kiaa0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

ZKSC1_MOUSE
θ value	0.62314 (rank : 6)	NC score	0.005182 (rank : 19)
Query Neighborhood Hits	12	Target Neighborhood Hits	755	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BGS3, Q7TS88, Q8BJ55, Q9CRN6	Gene names	Zkscan1
Domain Architecture	No domain graphic available
Description	Zinc finger with KRAB and SCAN domain-containing protein 1.

MOES_MOUSE
θ value	1.38821 (rank : 7)	NC score	0.015292 (rank : 15)
Query Neighborhood Hits	12	Target Neighborhood Hits	923	Shared Neighborhood Hits	3
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

RP1L1_MOUSE
θ value	1.38821 (rank : 8)	NC score	0.031908 (rank : 13)
Query Neighborhood Hits	12	Target Neighborhood Hits	170	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

MOES_HUMAN
θ value	3.0926 (rank : 9)	NC score	0.014236 (rank : 17)
Query Neighborhood Hits	12	Target Neighborhood Hits	892	Shared Neighborhood Hits	4
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

CF113_HUMAN
θ value	5.27518 (rank : 10)	NC score	0.018057 (rank : 14)
Query Neighborhood Hits	12	Target Neighborhood Hits	376	Shared Neighborhood Hits	3
SwissProt Accessions	Q96AP4, Q5TD92, Q6PJH7, Q96NV6	Gene names	C6orf113
Domain Architecture	No domain graphic available
Description	Zinc finger protein C6orf113.

TRI31_HUMAN
θ value	5.27518 (rank : 11)	NC score	0.007968 (rank : 18)
Query Neighborhood Hits	12	Target Neighborhood Hits	299	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

GCP60_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.014343 (rank : 16)
Query Neighborhood Hits	12	Target Neighborhood Hits	419	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H3P7, Q5VTJ0, Q6P9F1, Q8IZC5, Q8N4D6, Q9H6U3	Gene names	ACBD3, GCP60
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

BLM_HUMAN
θ value	θ > 10 (rank : 13)	NC score	0.062277 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	148	Shared Neighborhood Hits	2
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

BLM_MOUSE
θ value	θ > 10 (rank : 14)	NC score	0.063024 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

RECQ1_HUMAN
θ value	θ > 10 (rank : 15)	NC score	0.072924 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ1_MOUSE
θ value	θ > 10 (rank : 16)	NC score	0.073431 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	95	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ4_HUMAN
θ value	θ > 10 (rank : 17)	NC score	0.058690 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	177	Shared Neighborhood Hits	3
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RECQ4_MOUSE
θ value	θ > 10 (rank : 18)	NC score	0.056129 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	206	Shared Neighborhood Hits	2
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

RECQ5_HUMAN
θ value	θ > 10 (rank : 19)	NC score	0.068251 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	390	Shared Neighborhood Hits	3
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

Hits sorted by NC score

EXDL2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NVH0, Q8N3D3	Gene names	EXDL2, C14orf114
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.

EXDL2_MOUSE
NC score	0.996734 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VEG4	Gene names	Exdl2
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.

WRN_HUMAN
NC score	0.254095 (rank : 3)	θ value	3.64472e-09 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	132	Shared Neighborhood Hits	4
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

WRN_MOUSE
NC score	0.241808 (rank : 4)	θ value	1.38499e-08 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	295	Shared Neighborhood Hits	4
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

RECQ1_MOUSE
NC score	0.073431 (rank : 5)	θ value	θ > 10 (rank : 16)
Query Neighborhood Hits	12	Target Neighborhood Hits	95	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ1_HUMAN
NC score	0.072924 (rank : 6)	θ value	θ > 10 (rank : 15)
Query Neighborhood Hits	12	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ5_HUMAN
NC score	0.068251 (rank : 7)	θ value	θ > 10 (rank : 19)
Query Neighborhood Hits	12	Target Neighborhood Hits	390	Shared Neighborhood Hits	3
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

BLM_MOUSE
NC score	0.063024 (rank : 8)	θ value	θ > 10 (rank : 14)
Query Neighborhood Hits	12	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

BLM_HUMAN
NC score	0.062277 (rank : 9)	θ value	θ > 10 (rank : 13)
Query Neighborhood Hits	12	Target Neighborhood Hits	148	Shared Neighborhood Hits	2
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

RECQ4_HUMAN
NC score	0.058690 (rank : 10)	θ value	θ > 10 (rank : 17)
Query Neighborhood Hits	12	Target Neighborhood Hits	177	Shared Neighborhood Hits	3
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RECQ4_MOUSE
NC score	0.056129 (rank : 11)	θ value	θ > 10 (rank : 18)
Query Neighborhood Hits	12	Target Neighborhood Hits	206	Shared Neighborhood Hits	2
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

K0562_MOUSE
NC score	0.046253 (rank : 12)	θ value	0.62314 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	Q80V31, Q6ZQ95	Gene names	Kiaa0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

RP1L1_MOUSE
NC score	0.031908 (rank : 13)	θ value	1.38821 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	170	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

CF113_HUMAN
NC score	0.018057 (rank : 14)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	376	Shared Neighborhood Hits	3
SwissProt Accessions	Q96AP4, Q5TD92, Q6PJH7, Q96NV6	Gene names	C6orf113
Domain Architecture	No domain graphic available
Description	Zinc finger protein C6orf113.

MOES_MOUSE
NC score	0.015292 (rank : 15)	θ value	1.38821 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	923	Shared Neighborhood Hits	3
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

GCP60_HUMAN
NC score	0.014343 (rank : 16)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	419	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H3P7, Q5VTJ0, Q6P9F1, Q8IZC5, Q8N4D6, Q9H6U3	Gene names	ACBD3, GCP60
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

MOES_HUMAN
NC score	0.014236 (rank : 17)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	892	Shared Neighborhood Hits	4
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

TRI31_HUMAN
NC score	0.007968 (rank : 18)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	299	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

ZKSC1_MOUSE
NC score	0.005182 (rank : 19)	θ value	0.62314 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	755	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BGS3, Q7TS88, Q8BJ55, Q9CRN6	Gene names	Zkscan1
Domain Architecture	No domain graphic available
Description	Zinc finger with KRAB and SCAN domain-containing protein 1.