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Network neighborhood for query Sequence : DDX20_MOUSE

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DDX20_MOUSE
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DDX20_HUMAN
θ value	0 (rank : 1)	NC score	0.995100 (rank : 2)
Query Neighborhood Hits	177	Target Neighborhood Hits	121	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX20_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	177	Target Neighborhood Hits	177	Shared Neighborhood Hits	177
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX39_MOUSE
θ value	6.99855e-61 (rank : 3)	NC score	0.966627 (rank : 3)
Query Neighborhood Hits	177	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

UAP56_HUMAN
θ value	1.31987e-59 (rank : 4)	NC score	0.966198 (rank : 5)
Query Neighborhood Hits	177	Target Neighborhood Hits	96	Shared Neighborhood Hits	87
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
θ value	1.31987e-59 (rank : 5)	NC score	0.966169 (rank : 6)
Query Neighborhood Hits	177	Target Neighborhood Hits	96	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX39_HUMAN
θ value	1.7238e-59 (rank : 6)	NC score	0.966466 (rank : 4)
Query Neighborhood Hits	177	Target Neighborhood Hits	94	Shared Neighborhood Hits	87
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX6_HUMAN
θ value	4.24587e-58 (rank : 7)	NC score	0.965409 (rank : 7)
Query Neighborhood Hits	177	Target Neighborhood Hits	97	Shared Neighborhood Hits	84
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
θ value	4.24587e-58 (rank : 8)	NC score	0.965187 (rank : 8)
Query Neighborhood Hits	177	Target Neighborhood Hits	98	Shared Neighborhood Hits	84
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

IF4A2_HUMAN
θ value	9.45883e-58 (rank : 9)	NC score	0.963405 (rank : 9)
Query Neighborhood Hits	177	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
θ value	9.45883e-58 (rank : 10)	NC score	0.963405 (rank : 10)
Query Neighborhood Hits	177	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX48_MOUSE
θ value	2.7521e-57 (rank : 11)	NC score	0.962763 (rank : 14)
Query Neighborhood Hits	177	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX48_HUMAN
θ value	3.59435e-57 (rank : 12)	NC score	0.962817 (rank : 13)
Query Neighborhood Hits	177	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

IF4A1_HUMAN
θ value	4.69435e-57 (rank : 13)	NC score	0.963082 (rank : 11)
Query Neighborhood Hits	177	Target Neighborhood Hits	106	Shared Neighborhood Hits	87
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
θ value	4.69435e-57 (rank : 14)	NC score	0.963082 (rank : 12)
Query Neighborhood Hits	177	Target Neighborhood Hits	106	Shared Neighborhood Hits	87
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

DD19B_HUMAN
θ value	8.02596e-49 (rank : 15)	NC score	0.951669 (rank : 16)
Query Neighborhood Hits	177	Target Neighborhood Hits	109	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DD19A_HUMAN
θ value	3.04986e-48 (rank : 16)	NC score	0.951941 (rank : 15)
Query Neighborhood Hits	177	Target Neighborhood Hits	107	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19A_MOUSE
θ value	3.04986e-48 (rank : 17)	NC score	0.951643 (rank : 17)
Query Neighborhood Hits	177	Target Neighborhood Hits	105	Shared Neighborhood Hits	86
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DDX25_HUMAN
θ value	2.95404e-43 (rank : 18)	NC score	0.949327 (rank : 19)
Query Neighborhood Hits	177	Target Neighborhood Hits	93	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX25_MOUSE
θ value	3.26607e-42 (rank : 19)	NC score	0.948440 (rank : 20)
Query Neighborhood Hits	177	Target Neighborhood Hits	98	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX47_MOUSE
θ value	4.71619e-41 (rank : 20)	NC score	0.949368 (rank : 18)
Query Neighborhood Hits	177	Target Neighborhood Hits	97	Shared Neighborhood Hits	84
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX49_MOUSE
θ value	3.99248e-40 (rank : 21)	NC score	0.945582 (rank : 22)
Query Neighborhood Hits	177	Target Neighborhood Hits	119	Shared Neighborhood Hits	88
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX47_HUMAN
θ value	6.81017e-40 (rank : 22)	NC score	0.948270 (rank : 21)
Query Neighborhood Hits	177	Target Neighborhood Hits	97	Shared Neighborhood Hits	84
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX49_HUMAN
θ value	4.41421e-39 (rank : 23)	NC score	0.940806 (rank : 23)
Query Neighborhood Hits	177	Target Neighborhood Hits	223	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX27_MOUSE
θ value	6.37413e-38 (rank : 24)	NC score	0.940252 (rank : 24)
Query Neighborhood Hits	177	Target Neighborhood Hits	174	Shared Neighborhood Hits	88
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_HUMAN
θ value	8.32485e-38 (rank : 25)	NC score	0.938748 (rank : 25)
Query Neighborhood Hits	177	Target Neighborhood Hits	197	Shared Neighborhood Hits	91
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX43_HUMAN
θ value	3.16345e-37 (rank : 26)	NC score	0.933127 (rank : 28)
Query Neighborhood Hits	177	Target Neighborhood Hits	120	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX10_MOUSE
θ value	7.79185e-36 (rank : 27)	NC score	0.921980 (rank : 45)
Query Neighborhood Hits	177	Target Neighborhood Hits	233	Shared Neighborhood Hits	89
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX17_HUMAN
θ value	1.46948e-34 (rank : 28)	NC score	0.924821 (rank : 43)
Query Neighborhood Hits	177	Target Neighborhood Hits	104	Shared Neighborhood Hits	85
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX17_MOUSE
θ value	1.46948e-34 (rank : 29)	NC score	0.924943 (rank : 42)
Query Neighborhood Hits	177	Target Neighborhood Hits	105	Shared Neighborhood Hits	84
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX53_HUMAN
θ value	5.584e-34 (rank : 30)	NC score	0.927967 (rank : 35)
Query Neighborhood Hits	177	Target Neighborhood Hits	124	Shared Neighborhood Hits	81
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX54_MOUSE
θ value	7.29293e-34 (rank : 31)	NC score	0.936340 (rank : 26)
Query Neighborhood Hits	177	Target Neighborhood Hits	124	Shared Neighborhood Hits	85
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX23_HUMAN
θ value	2.12192e-33 (rank : 32)	NC score	0.907490 (rank : 59)
Query Neighborhood Hits	177	Target Neighborhood Hits	486	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX41_MOUSE
θ value	2.77131e-33 (rank : 33)	NC score	0.932241 (rank : 31)
Query Neighborhood Hits	177	Target Neighborhood Hits	115	Shared Neighborhood Hits	90
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX41_HUMAN
θ value	4.72714e-33 (rank : 34)	NC score	0.932768 (rank : 29)
Query Neighborhood Hits	177	Target Neighborhood Hits	111	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX3Y_HUMAN
θ value	1.0531e-32 (rank : 35)	NC score	0.919413 (rank : 52)
Query Neighborhood Hits	177	Target Neighborhood Hits	121	Shared Neighborhood Hits	90
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX3X_HUMAN
θ value	1.37539e-32 (rank : 36)	NC score	0.919980 (rank : 48)
Query Neighborhood Hits	177	Target Neighborhood Hits	122	Shared Neighborhood Hits	91
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX3X_MOUSE
θ value	1.37539e-32 (rank : 37)	NC score	0.919595 (rank : 51)
Query Neighborhood Hits	177	Target Neighborhood Hits	117	Shared Neighborhood Hits	91
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

PL10_MOUSE
θ value	1.79631e-32 (rank : 38)	NC score	0.920275 (rank : 47)
Query Neighborhood Hits	177	Target Neighborhood Hits	120	Shared Neighborhood Hits	91
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX54_HUMAN
θ value	2.34606e-32 (rank : 39)	NC score	0.932194 (rank : 32)
Query Neighborhood Hits	177	Target Neighborhood Hits	170	Shared Neighborhood Hits	84
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX10_HUMAN
θ value	4.00176e-32 (rank : 40)	NC score	0.919301 (rank : 53)
Query Neighborhood Hits	177	Target Neighborhood Hits	210	Shared Neighborhood Hits	84
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX4_MOUSE
θ value	4.00176e-32 (rank : 41)	NC score	0.927970 (rank : 34)
Query Neighborhood Hits	177	Target Neighborhood Hits	100	Shared Neighborhood Hits	85
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX4_HUMAN
θ value	5.22648e-32 (rank : 42)	NC score	0.926817 (rank : 37)
Query Neighborhood Hits	177	Target Neighborhood Hits	123	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX3Y_MOUSE
θ value	9.8567e-31 (rank : 43)	NC score	0.918636 (rank : 54)
Query Neighborhood Hits	177	Target Neighborhood Hits	126	Shared Neighborhood Hits	92
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX46_HUMAN
θ value	1.85889e-29 (rank : 44)	NC score	0.908426 (rank : 57)
Query Neighborhood Hits	177	Target Neighborhood Hits	357	Shared Neighborhood Hits	95
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
θ value	1.85889e-29 (rank : 45)	NC score	0.906627 (rank : 60)
Query Neighborhood Hits	177	Target Neighborhood Hits	358	Shared Neighborhood Hits	100
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX52_HUMAN
θ value	1.85889e-29 (rank : 46)	NC score	0.933760 (rank : 27)
Query Neighborhood Hits	177	Target Neighborhood Hits	107	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX5_HUMAN
θ value	5.40856e-29 (rank : 47)	NC score	0.919742 (rank : 49)
Query Neighborhood Hits	177	Target Neighborhood Hits	102	Shared Neighborhood Hits	84
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
θ value	7.06379e-29 (rank : 48)	NC score	0.919692 (rank : 50)
Query Neighborhood Hits	177	Target Neighborhood Hits	101	Shared Neighborhood Hits	84
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX52_MOUSE
θ value	1.57365e-28 (rank : 49)	NC score	0.932657 (rank : 30)
Query Neighborhood Hits	177	Target Neighborhood Hits	101	Shared Neighborhood Hits	85
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX55_HUMAN
θ value	1.73987e-27 (rank : 50)	NC score	0.926134 (rank : 40)
Query Neighborhood Hits	177	Target Neighborhood Hits	122	Shared Neighborhood Hits	82
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX21_HUMAN
θ value	3.87602e-27 (rank : 51)	NC score	0.905521 (rank : 61)
Query Neighborhood Hits	177	Target Neighborhood Hits	308	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX21_MOUSE
θ value	8.63488e-27 (rank : 52)	NC score	0.899193 (rank : 63)
Query Neighborhood Hits	177	Target Neighborhood Hits	350	Shared Neighborhood Hits	102
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX18_MOUSE
θ value	3.28125e-26 (rank : 53)	NC score	0.924029 (rank : 44)
Query Neighborhood Hits	177	Target Neighborhood Hits	115	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX55_MOUSE
θ value	4.28545e-26 (rank : 54)	NC score	0.926150 (rank : 39)
Query Neighborhood Hits	177	Target Neighborhood Hits	111	Shared Neighborhood Hits	82
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX18_HUMAN
θ value	2.35151e-24 (rank : 55)	NC score	0.921108 (rank : 46)
Query Neighborhood Hits	177	Target Neighborhood Hits	124	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX50_MOUSE
θ value	2.35151e-24 (rank : 56)	NC score	0.912392 (rank : 55)
Query Neighborhood Hits	177	Target Neighborhood Hits	137	Shared Neighborhood Hits	88
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX28_MOUSE
θ value	3.07116e-24 (rank : 57)	NC score	0.929148 (rank : 33)
Query Neighborhood Hits	177	Target Neighborhood Hits	112	Shared Neighborhood Hits	87
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX50_HUMAN
θ value	5.23862e-24 (rank : 58)	NC score	0.911599 (rank : 56)
Query Neighborhood Hits	177	Target Neighborhood Hits	132	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX31_HUMAN
θ value	2.59989e-23 (rank : 59)	NC score	0.908051 (rank : 58)
Query Neighborhood Hits	177	Target Neighborhood Hits	132	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX56_HUMAN
θ value	2.20094e-22 (rank : 60)	NC score	0.926538 (rank : 38)
Query Neighborhood Hits	177	Target Neighborhood Hits	77	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DDX28_HUMAN
θ value	6.40375e-22 (rank : 61)	NC score	0.926972 (rank : 36)
Query Neighborhood Hits	177	Target Neighborhood Hits	103	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX56_MOUSE
θ value	3.17815e-21 (rank : 62)	NC score	0.925748 (rank : 41)
Query Neighborhood Hits	177	Target Neighborhood Hits	87	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX24_MOUSE
θ value	1.33526e-19 (rank : 63)	NC score	0.900362 (rank : 62)
Query Neighborhood Hits	177	Target Neighborhood Hits	147	Shared Neighborhood Hits	86
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX24_HUMAN
θ value	3.88503e-19 (rank : 64)	NC score	0.896185 (rank : 65)
Query Neighborhood Hits	177	Target Neighborhood Hits	190	Shared Neighborhood Hits	92
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX51_HUMAN
θ value	6.62687e-19 (rank : 65)	NC score	0.881474 (rank : 66)
Query Neighborhood Hits	177	Target Neighborhood Hits	332	Shared Neighborhood Hits	94
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX1_HUMAN
θ value	1.92812e-18 (rank : 66)	NC score	0.871908 (rank : 68)
Query Neighborhood Hits	177	Target Neighborhood Hits	110	Shared Neighborhood Hits	84
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX1_MOUSE
θ value	2.5182e-18 (rank : 67)	NC score	0.873147 (rank : 67)
Query Neighborhood Hits	177	Target Neighborhood Hits	112	Shared Neighborhood Hits	84
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX51_MOUSE
θ value	2.5182e-18 (rank : 68)	NC score	0.896624 (rank : 64)
Query Neighborhood Hits	177	Target Neighborhood Hits	130	Shared Neighborhood Hits	84
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

BLM_MOUSE
θ value	1.43324e-05 (rank : 69)	NC score	0.479093 (rank : 71)
Query Neighborhood Hits	177	Target Neighborhood Hits	108	Shared Neighborhood Hits	72
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

BLM_HUMAN
θ value	9.29e-05 (rank : 70)	NC score	0.463321 (rank : 72)
Query Neighborhood Hits	177	Target Neighborhood Hits	148	Shared Neighborhood Hits	74
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

NOL8_HUMAN
θ value	0.000461057 (rank : 71)	NC score	0.042204 (rank : 103)
Query Neighborhood Hits	177	Target Neighborhood Hits	297	Shared Neighborhood Hits	27
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

DICER_HUMAN
θ value	0.00102713 (rank : 72)	NC score	0.399831 (rank : 78)
Query Neighborhood Hits	177	Target Neighborhood Hits	126	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

RECQ4_MOUSE
θ value	0.00134147 (rank : 73)	NC score	0.505195 (rank : 70)
Query Neighborhood Hits	177	Target Neighborhood Hits	206	Shared Neighborhood Hits	88
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

DICER_MOUSE
θ value	0.00298849 (rank : 74)	NC score	0.395905 (rank : 79)
Query Neighborhood Hits	177	Target Neighborhood Hits	140	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

RECQ4_HUMAN
θ value	0.00665767 (rank : 75)	NC score	0.517453 (rank : 69)
Query Neighborhood Hits	177	Target Neighborhood Hits	177	Shared Neighborhood Hits	88
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

OXR1_MOUSE
θ value	0.0252991 (rank : 76)	NC score	0.026666 (rank : 111)
Query Neighborhood Hits	177	Target Neighborhood Hits	516	Shared Neighborhood Hits	27
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

FANCM_HUMAN
θ value	0.0330416 (rank : 77)	NC score	0.410098 (rank : 75)
Query Neighborhood Hits	177	Target Neighborhood Hits	210	Shared Neighborhood Hits	80
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

NCLN_MOUSE
θ value	0.0563607 (rank : 78)	NC score	0.047569 (rank : 98)
Query Neighborhood Hits	177	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VCM8, Q8C7Y4, Q9CX81	Gene names	Ncln
Domain Architecture	No domain graphic available
Description	Nicalin precursor (Nicastrin-like protein).

PHF1_HUMAN
θ value	0.0563607 (rank : 79)	NC score	0.020489 (rank : 118)
Query Neighborhood Hits	177	Target Neighborhood Hits	117	Shared Neighborhood Hits	10
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

FANCM_MOUSE
θ value	0.125558 (rank : 80)	NC score	0.403114 (rank : 77)
Query Neighborhood Hits	177	Target Neighborhood Hits	177	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

CHD4_HUMAN
θ value	0.163984 (rank : 81)	NC score	0.055053 (rank : 93)
Query Neighborhood Hits	177	Target Neighborhood Hits	365	Shared Neighborhood Hits	39
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	0.163984 (rank : 82)	NC score	0.054672 (rank : 94)
Query Neighborhood Hits	177	Target Neighborhood Hits	408	Shared Neighborhood Hits	42
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD1_HUMAN
θ value	0.21417 (rank : 83)	NC score	0.043873 (rank : 101)
Query Neighborhood Hits	177	Target Neighborhood Hits	337	Shared Neighborhood Hits	37
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_MOUSE
θ value	0.21417 (rank : 84)	NC score	0.044459 (rank : 100)
Query Neighborhood Hits	177	Target Neighborhood Hits	266	Shared Neighborhood Hits	38
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

NCLN_HUMAN
θ value	0.21417 (rank : 85)	NC score	0.042936 (rank : 102)
Query Neighborhood Hits	177	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q969V3, O75252, Q6FI60, Q6ZMB7, Q8TAT7, Q96H48, Q96IS7, Q9BQH9, Q9BTX4, Q9NPP2	Gene names	NCLN
Domain Architecture	No domain graphic available
Description	Nicalin precursor (Nicastrin-like protein).

PPHLN_HUMAN
θ value	0.21417 (rank : 86)	NC score	0.029456 (rank : 107)
Query Neighborhood Hits	177	Target Neighborhood Hits	75	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NEY8, Q86YT2, Q8IXN3, Q8TB09, Q96NB9, Q9NXL4, Q9P0P6, Q9P0R9	Gene names	PPHLN1
Domain Architecture	No domain graphic available
Description	Periphilin-1 (Gastric cancer antigen Ga50).

CC026_MOUSE
θ value	0.279714 (rank : 87)	NC score	0.166551 (rank : 88)
Query Neighborhood Hits	177	Target Neighborhood Hits	38	Shared Neighborhood Hits	28
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

ENL_HUMAN
θ value	0.279714 (rank : 88)	NC score	0.024548 (rank : 113)
Query Neighborhood Hits	177	Target Neighborhood Hits	305	Shared Neighborhood Hits	22
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

LMBL3_MOUSE
θ value	0.279714 (rank : 89)	NC score	0.012695 (rank : 135)
Query Neighborhood Hits	177	Target Neighborhood Hits	212	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BLB7, Q641L7, Q6ZPI2, Q8C0G4	Gene names	L3mbtl3
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein).

PO6F2_MOUSE
θ value	0.279714 (rank : 90)	NC score	0.008406 (rank : 156)
Query Neighborhood Hits	177	Target Neighborhood Hits	639	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

WRN_HUMAN
θ value	0.279714 (rank : 91)	NC score	0.431911 (rank : 73)
Query Neighborhood Hits	177	Target Neighborhood Hits	132	Shared Neighborhood Hits	80
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

ARI4A_HUMAN
θ value	0.365318 (rank : 92)	NC score	0.029643 (rank : 106)
Query Neighborhood Hits	177	Target Neighborhood Hits	434	Shared Neighborhood Hits	24
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

CJ078_MOUSE
θ value	0.365318 (rank : 93)	NC score	0.024573 (rank : 112)
Query Neighborhood Hits	177	Target Neighborhood Hits	559	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

ENKUR_HUMAN
θ value	0.47712 (rank : 94)	NC score	0.020520 (rank : 117)
Query Neighborhood Hits	177	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TC29	Gene names	C10orf63
Domain Architecture	No domain graphic available
Description	Enkurin.

K1543_HUMAN
θ value	0.47712 (rank : 95)	NC score	0.015504 (rank : 127)
Query Neighborhood Hits	177	Target Neighborhood Hits	435	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

RAPH1_HUMAN
θ value	0.47712 (rank : 96)	NC score	0.011003 (rank : 141)
Query Neighborhood Hits	177	Target Neighborhood Hits	593	Shared Neighborhood Hits	22
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RECQ5_HUMAN
θ value	0.47712 (rank : 97)	NC score	0.426346 (rank : 74)
Query Neighborhood Hits	177	Target Neighborhood Hits	390	Shared Neighborhood Hits	93
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

SFRIP_HUMAN
θ value	0.47712 (rank : 98)	NC score	0.047690 (rank : 97)
Query Neighborhood Hits	177	Target Neighborhood Hits	530	Shared Neighborhood Hits	40
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

WRN_MOUSE
θ value	0.47712 (rank : 99)	NC score	0.404485 (rank : 76)
Query Neighborhood Hits	177	Target Neighborhood Hits	295	Shared Neighborhood Hits	80
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

CNOT3_HUMAN
θ value	0.62314 (rank : 100)	NC score	0.019448 (rank : 120)
Query Neighborhood Hits	177	Target Neighborhood Hits	425	Shared Neighborhood Hits	14
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

EXO1_HUMAN
θ value	0.62314 (rank : 101)	NC score	0.017088 (rank : 124)
Query Neighborhood Hits	177	Target Neighborhood Hits	82	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UQ84, O60545, O75214, O75466, Q5T396, Q96IJ1, Q9UG38, Q9UNW0	Gene names	EXO1, EXOI, HEX1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (hExo1) (Exonuclease I) (hExoI).

IWS1_HUMAN
θ value	0.62314 (rank : 102)	NC score	0.032558 (rank : 105)
Query Neighborhood Hits	177	Target Neighborhood Hits	1241	Shared Neighborhood Hits	65
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MINT_MOUSE
θ value	0.62314 (rank : 103)	NC score	0.021130 (rank : 116)
Query Neighborhood Hits	177	Target Neighborhood Hits	1514	Shared Neighborhood Hits	58
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CNOT3_MOUSE
θ value	0.813845 (rank : 104)	NC score	0.018634 (rank : 121)
Query Neighborhood Hits	177	Target Neighborhood Hits	504	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

SOCS6_HUMAN
θ value	0.813845 (rank : 105)	NC score	0.009631 (rank : 148)
Query Neighborhood Hits	177	Target Neighborhood Hits	126	Shared Neighborhood Hits	2
SwissProt Accessions	O14544	Gene names	SOCS6, CIS4, SOCS4
Domain Architecture
Description	Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor of cytokine signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4) (CIS-4).

TXND2_HUMAN
θ value	0.813845 (rank : 106)	NC score	0.026780 (rank : 110)
Query Neighborhood Hits	177	Target Neighborhood Hits	793	Shared Neighborhood Hits	48
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

CC026_HUMAN
θ value	1.06291 (rank : 107)	NC score	0.193972 (rank : 86)
Query Neighborhood Hits	177	Target Neighborhood Hits	39	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

CDN1C_MOUSE
θ value	1.06291 (rank : 108)	NC score	0.016559 (rank : 125)
Query Neighborhood Hits	177	Target Neighborhood Hits	161	Shared Neighborhood Hits	8
SwissProt Accessions	P49919	Gene names	Cdkn1c, Kip2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

PPHLN_MOUSE
θ value	1.06291 (rank : 109)	NC score	0.028710 (rank : 108)
Query Neighborhood Hits	177	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2H1, Q8BUZ6	Gene names	Pphln1
Domain Architecture	No domain graphic available
Description	Periphilin-1.

TSH1_MOUSE
θ value	1.06291 (rank : 110)	NC score	0.014007 (rank : 130)
Query Neighborhood Hits	177	Target Neighborhood Hits	675	Shared Neighborhood Hits	22
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

TTC14_HUMAN
θ value	1.06291 (rank : 111)	NC score	0.013667 (rank : 132)
Query Neighborhood Hits	177	Target Neighborhood Hits	274	Shared Neighborhood Hits	7
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

AKAP2_MOUSE
θ value	1.38821 (rank : 112)	NC score	0.011226 (rank : 139)
Query Neighborhood Hits	177	Target Neighborhood Hits	385	Shared Neighborhood Hits	17
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

CYTSA_HUMAN
θ value	1.38821 (rank : 113)	NC score	0.003047 (rank : 181)
Query Neighborhood Hits	177	Target Neighborhood Hits	1138	Shared Neighborhood Hits	18
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

EXOC3_HUMAN
θ value	1.38821 (rank : 114)	NC score	0.013828 (rank : 131)
Query Neighborhood Hits	177	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	O60645, Q8TEN6, Q8WUW0, Q96DI4	Gene names	EXOC3, SEC6, SEC6L1
Domain Architecture
Description	Exocyst complex component 3 (Exocyst complex component Sec6).

GPTC8_HUMAN
θ value	1.38821 (rank : 115)	NC score	0.018079 (rank : 122)
Query Neighborhood Hits	177	Target Neighborhood Hits	366	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

IFIH1_HUMAN
θ value	1.38821 (rank : 116)	NC score	0.304202 (rank : 82)
Query Neighborhood Hits	177	Target Neighborhood Hits	96	Shared Neighborhood Hits	73
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

NKTR_HUMAN
θ value	1.38821 (rank : 117)	NC score	0.023510 (rank : 114)
Query Neighborhood Hits	177	Target Neighborhood Hits	658	Shared Neighborhood Hits	48
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

NPM_HUMAN
θ value	1.38821 (rank : 118)	NC score	0.021799 (rank : 115)
Query Neighborhood Hits	177	Target Neighborhood Hits	69	Shared Neighborhood Hits	11
SwissProt Accessions	P06748, P08693, Q12826, Q13440, Q13441, Q14115, Q5EU94, Q5EU95, Q5EU96, Q5EU97, Q5EU98, Q5EU99, Q6V962, Q8WTW5, Q96AT6, Q96DC4, Q96EA5	Gene names	NPM1, NPM
Domain Architecture
Description	Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Numatrin) (Nucleolar protein NO38).

SYN3_MOUSE
θ value	1.38821 (rank : 119)	NC score	0.009175 (rank : 150)
Query Neighborhood Hits	177	Target Neighborhood Hits	200	Shared Neighborhood Hits	14
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

BCL7A_HUMAN
θ value	1.81305 (rank : 120)	NC score	0.017405 (rank : 123)
Query Neighborhood Hits	177	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q4VC05, Q13843	Gene names	BCL7A
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

PO6F2_HUMAN
θ value	1.81305 (rank : 121)	NC score	0.005817 (rank : 164)
Query Neighborhood Hits	177	Target Neighborhood Hits	618	Shared Neighborhood Hits	16
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

TTC28_HUMAN
θ value	1.81305 (rank : 122)	NC score	0.008422 (rank : 155)
Query Neighborhood Hits	177	Target Neighborhood Hits	271	Shared Neighborhood Hits	16
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

UBQL3_MOUSE
θ value	1.81305 (rank : 123)	NC score	0.007861 (rank : 159)
Query Neighborhood Hits	177	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C5U9	Gene names	Ubqln3
Domain Architecture
Description	Ubiquilin-3.

BAZ2A_HUMAN
θ value	2.36792 (rank : 124)	NC score	0.009388 (rank : 149)
Query Neighborhood Hits	177	Target Neighborhood Hits	780	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

CHD9_MOUSE
θ value	2.36792 (rank : 125)	NC score	0.026903 (rank : 109)
Query Neighborhood Hits	177	Target Neighborhood Hits	427	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

GAB1_MOUSE
θ value	2.36792 (rank : 126)	NC score	0.008087 (rank : 158)
Query Neighborhood Hits	177	Target Neighborhood Hits	233	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

MINT_HUMAN
θ value	2.36792 (rank : 127)	NC score	0.015289 (rank : 128)
Query Neighborhood Hits	177	Target Neighborhood Hits	1291	Shared Neighborhood Hits	46
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NCOR1_MOUSE
θ value	2.36792 (rank : 128)	NC score	0.007543 (rank : 160)
Query Neighborhood Hits	177	Target Neighborhood Hits	521	Shared Neighborhood Hits	20
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

TAB3_HUMAN
θ value	2.36792 (rank : 129)	NC score	0.010330 (rank : 145)
Query Neighborhood Hits	177	Target Neighborhood Hits	168	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

ABCA2_HUMAN
θ value	3.0926 (rank : 130)	NC score	0.002344 (rank : 183)
Query Neighborhood Hits	177	Target Neighborhood Hits	143	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BZC7	Gene names	ABCA2, ABC2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

BCL7A_MOUSE
θ value	3.0926 (rank : 131)	NC score	0.015669 (rank : 126)
Query Neighborhood Hits	177	Target Neighborhood Hits	74	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CXE2, Q8C361, Q8C8M8, Q8VD15	Gene names	Bcl7a
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

CO039_HUMAN
θ value	3.0926 (rank : 132)	NC score	0.008808 (rank : 153)
Query Neighborhood Hits	177	Target Neighborhood Hits	264	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

MECP2_HUMAN
θ value	3.0926 (rank : 133)	NC score	0.009985 (rank : 146)
Query Neighborhood Hits	177	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	P51608, O15233	Gene names	MECP2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

SRRM2_MOUSE
θ value	3.0926 (rank : 134)	NC score	0.020468 (rank : 119)
Query Neighborhood Hits	177	Target Neighborhood Hits	1470	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ANR11_HUMAN
θ value	4.03905 (rank : 135)	NC score	0.004610 (rank : 170)
Query Neighborhood Hits	177	Target Neighborhood Hits	1289	Shared Neighborhood Hits	40
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

APC_HUMAN
θ value	4.03905 (rank : 136)	NC score	0.011919 (rank : 137)
Query Neighborhood Hits	177	Target Neighborhood Hits	603	Shared Neighborhood Hits	28
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

APC_MOUSE
θ value	4.03905 (rank : 137)	NC score	0.012275 (rank : 136)
Query Neighborhood Hits	177	Target Neighborhood Hits	441	Shared Neighborhood Hits	18
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

BBX_HUMAN
θ value	4.03905 (rank : 138)	NC score	0.008482 (rank : 154)
Query Neighborhood Hits	177	Target Neighborhood Hits	167	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WY36, Q2TAJ1, Q7L3J8, Q7LBY8, Q8NDB0, Q8WY35, Q9H0J6	Gene names	BBX, HBP2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

CDT1_HUMAN
θ value	4.03905 (rank : 139)	NC score	0.009092 (rank : 151)
Query Neighborhood Hits	177	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H211, Q86XX9, Q96CJ5, Q96GK5, Q96H67, Q96HE6, Q9BWM0	Gene names	CDT1
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP).

CYTSA_MOUSE
θ value	4.03905 (rank : 140)	NC score	0.000799 (rank : 185)
Query Neighborhood Hits	177	Target Neighborhood Hits	1104	Shared Neighborhood Hits	18
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

JHD2C_MOUSE
θ value	4.03905 (rank : 141)	NC score	0.011328 (rank : 138)
Query Neighborhood Hits	177	Target Neighborhood Hits	297	Shared Neighborhood Hits	16
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

LR37A_HUMAN
θ value	4.03905 (rank : 142)	NC score	0.005270 (rank : 167)
Query Neighborhood Hits	177	Target Neighborhood Hits	720	Shared Neighborhood Hits	29
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

NPDC1_HUMAN
θ value	4.03905 (rank : 143)	NC score	0.010992 (rank : 142)
Query Neighborhood Hits	177	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQX5, Q9BTD6, Q9BXT3, Q9NQS2, Q9Y434	Gene names	NPDC1
Domain Architecture
Description	Neural proliferation differentiation and control protein 1 precursor (NPDC-1 protein).

TIRAP_MOUSE
θ value	4.03905 (rank : 144)	NC score	0.009839 (rank : 147)
Query Neighborhood Hits	177	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q99JY1, Q91ZW0	Gene names	Tirap, Mal
Domain Architecture
Description	Toll-interleukin 1 receptor domain-containing adapter protein (TIR domain-containing adapter protein) (MyD88 adapter-like protein) (Adaptor protein Wyatt).

BBX_MOUSE
θ value	5.27518 (rank : 145)	NC score	0.006982 (rank : 161)
Query Neighborhood Hits	177	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

BSN_HUMAN
θ value	5.27518 (rank : 146)	NC score	0.004890 (rank : 168)
Query Neighborhood Hits	177	Target Neighborhood Hits	1537	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CHD3_HUMAN
θ value	5.27518 (rank : 147)	NC score	0.045496 (rank : 99)
Query Neighborhood Hits	177	Target Neighborhood Hits	397	Shared Neighborhood Hits	36
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CJ012_HUMAN
θ value	5.27518 (rank : 148)	NC score	0.014119 (rank : 129)
Query Neighborhood Hits	177	Target Neighborhood Hits	467	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

IFIH1_MOUSE
θ value	5.27518 (rank : 149)	NC score	0.285202 (rank : 84)
Query Neighborhood Hits	177	Target Neighborhood Hits	126	Shared Neighborhood Hits	78
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

MITF_HUMAN
θ value	5.27518 (rank : 150)	NC score	0.004207 (rank : 174)
Query Neighborhood Hits	177	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

NKTR_MOUSE
θ value	5.27518 (rank : 151)	NC score	0.010592 (rank : 144)
Query Neighborhood Hits	177	Target Neighborhood Hits	417	Shared Neighborhood Hits	33
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

PELI2_HUMAN
θ value	5.27518 (rank : 152)	NC score	0.004338 (rank : 172)
Query Neighborhood Hits	177	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HAT8	Gene names	PELI2
Domain Architecture
Description	Protein pellino homolog 2 (Pellino-2).

PHF2_MOUSE
θ value	5.27518 (rank : 153)	NC score	0.004409 (rank : 171)
Query Neighborhood Hits	177	Target Neighborhood Hits	241	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

RECQ1_HUMAN
θ value	5.27518 (rank : 154)	NC score	0.389293 (rank : 80)
Query Neighborhood Hits	177	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

SPEG_MOUSE
θ value	5.27518 (rank : 155)	NC score	-0.005796 (rank : 186)
Query Neighborhood Hits	177	Target Neighborhood Hits	1959	Shared Neighborhood Hits	47
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TARA_MOUSE
θ value	5.27518 (rank : 156)	NC score	0.011089 (rank : 140)
Query Neighborhood Hits	177	Target Neighborhood Hits	1133	Shared Neighborhood Hits	41
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TMCC3_MOUSE
θ value	5.27518 (rank : 157)	NC score	0.003973 (rank : 175)
Query Neighborhood Hits	177	Target Neighborhood Hits	192	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R310	Gene names	Tmcc3
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 3.

EMSY_MOUSE
θ value	6.88961 (rank : 158)	NC score	0.010843 (rank : 143)
Query Neighborhood Hits	177	Target Neighborhood Hits	294	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

EP300_HUMAN
θ value	6.88961 (rank : 159)	NC score	0.003271 (rank : 179)
Query Neighborhood Hits	177	Target Neighborhood Hits	821	Shared Neighborhood Hits	31
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

JERKY_HUMAN
θ value	6.88961 (rank : 160)	NC score	0.005603 (rank : 165)
Query Neighborhood Hits	177	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	O75564, O75565	Gene names	JRK, JH8
Domain Architecture
Description	Jerky protein homolog.

NFH_MOUSE
θ value	6.88961 (rank : 161)	NC score	0.008859 (rank : 152)
Query Neighborhood Hits	177	Target Neighborhood Hits	2247	Shared Neighborhood Hits	68
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RBMX2_HUMAN
θ value	6.88961 (rank : 162)	NC score	0.003288 (rank : 178)
Query Neighborhood Hits	177	Target Neighborhood Hits	351	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y388, Q5JY82, Q9Y3I8	Gene names	RBMX2
Domain Architecture
Description	RNA-binding motif protein, X-linked 2.

RECQ1_MOUSE
θ value	6.88961 (rank : 163)	NC score	0.387292 (rank : 81)
Query Neighborhood Hits	177	Target Neighborhood Hits	95	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

SRRM2_HUMAN
θ value	6.88961 (rank : 164)	NC score	0.013447 (rank : 133)
Query Neighborhood Hits	177	Target Neighborhood Hits	1296	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TAB3_MOUSE
θ value	6.88961 (rank : 165)	NC score	0.008347 (rank : 157)
Query Neighborhood Hits	177	Target Neighborhood Hits	273	Shared Neighborhood Hits	11
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

ZCH10_MOUSE
θ value	6.88961 (rank : 166)	NC score	0.013053 (rank : 134)
Query Neighborhood Hits	177	Target Neighborhood Hits	133	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

CHD5_HUMAN
θ value	8.99809 (rank : 167)	NC score	0.040135 (rank : 104)
Query Neighborhood Hits	177	Target Neighborhood Hits	349	Shared Neighborhood Hits	32
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CMGA_MOUSE
θ value	8.99809 (rank : 168)	NC score	0.006561 (rank : 163)
Query Neighborhood Hits	177	Target Neighborhood Hits	172	Shared Neighborhood Hits	9
SwissProt Accessions	P26339	Gene names	Chga
Domain Architecture
Description	Chromogranin A precursor (CgA) [Contains: Pancreastatin; Beta-granin; WE-14].

DNL1_HUMAN
θ value	8.99809 (rank : 169)	NC score	0.006582 (rank : 162)
Query Neighborhood Hits	177	Target Neighborhood Hits	216	Shared Neighborhood Hits	16
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

EYA4_MOUSE
θ value	8.99809 (rank : 170)	NC score	0.003050 (rank : 180)
Query Neighborhood Hits	177	Target Neighborhood Hits	74	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z191	Gene names	Eya4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

K2027_HUMAN
θ value	8.99809 (rank : 171)	NC score	0.005503 (rank : 166)
Query Neighborhood Hits	177	Target Neighborhood Hits	194	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

NFH_HUMAN
θ value	8.99809 (rank : 172)	NC score	0.004787 (rank : 169)
Query Neighborhood Hits	177	Target Neighborhood Hits	1242	Shared Neighborhood Hits	45
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RBM28_MOUSE
θ value	8.99809 (rank : 173)	NC score	0.002714 (rank : 182)
Query Neighborhood Hits	177	Target Neighborhood Hits	368	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CGC6, Q8BG25, Q8VEJ8, Q9CS22, Q9CSE6	Gene names	Rbm28
Domain Architecture	No domain graphic available
Description	RNA-binding protein 28 (RNA-binding motif protein 28).

RERE_HUMAN
θ value	8.99809 (rank : 174)	NC score	0.001599 (rank : 184)
Query Neighborhood Hits	177	Target Neighborhood Hits	779	Shared Neighborhood Hits	27
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

TRA2A_HUMAN
θ value	8.99809 (rank : 175)	NC score	0.003450 (rank : 176)
Query Neighborhood Hits	177	Target Neighborhood Hits	222	Shared Neighborhood Hits	14
SwissProt Accessions	Q13595	Gene names	TRA2A
Domain Architecture
Description	Transformer-2 protein homolog (TRA-2 alpha).

TRA2A_MOUSE
θ value	8.99809 (rank : 176)	NC score	0.003428 (rank : 177)
Query Neighborhood Hits	177	Target Neighborhood Hits	219	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PFR5	Gene names	Tra2a
Domain Architecture	No domain graphic available
Description	Transformer-2 protein homolog (TRA-2 alpha).

UBP8_MOUSE
θ value	8.99809 (rank : 177)	NC score	0.004313 (rank : 173)
Query Neighborhood Hits	177	Target Neighborhood Hits	362	Shared Neighborhood Hits	19
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

DDX58_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.144430 (rank : 89)
Query Neighborhood Hits	177	Target Neighborhood Hits	105	Shared Neighborhood Hits	55
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DDX58_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.173399 (rank : 87)
Query Neighborhood Hits	177	Target Neighborhood Hits	99	Shared Neighborhood Hits	58
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

HELC1_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.084360 (rank : 91)
Query Neighborhood Hits	177	Target Neighborhood Hits	71	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

LGP2_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.282574 (rank : 85)
Query Neighborhood Hits	177	Target Neighborhood Hits	94	Shared Neighborhood Hits	69
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

LGP2_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.299150 (rank : 83)
Query Neighborhood Hits	177	Target Neighborhood Hits	86	Shared Neighborhood Hits	66
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

SMAL1_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.075706 (rank : 92)
Query Neighborhood Hits	177	Target Neighborhood Hits	174	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

SMAL1_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.054122 (rank : 95)
Query Neighborhood Hits	177	Target Neighborhood Hits	157	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

SMCA1_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.053908 (rank : 96)
Query Neighborhood Hits	177	Target Neighborhood Hits	117	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

U520_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.108533 (rank : 90)
Query Neighborhood Hits	177	Target Neighborhood Hits	88	Shared Neighborhood Hits	42
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

Hits sorted by NC score

DDX20_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	177	Target Neighborhood Hits	177	Shared Neighborhood Hits	177
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX20_HUMAN
NC score	0.995100 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	177	Target Neighborhood Hits	121	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX39_MOUSE
NC score	0.966627 (rank : 3)	θ value	6.99855e-61 (rank : 3)
Query Neighborhood Hits	177	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX39_HUMAN
NC score	0.966466 (rank : 4)	θ value	1.7238e-59 (rank : 6)
Query Neighborhood Hits	177	Target Neighborhood Hits	94	Shared Neighborhood Hits	87
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

UAP56_HUMAN
NC score	0.966198 (rank : 5)	θ value	1.31987e-59 (rank : 4)
Query Neighborhood Hits	177	Target Neighborhood Hits	96	Shared Neighborhood Hits	87
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
NC score	0.966169 (rank : 6)	θ value	1.31987e-59 (rank : 5)
Query Neighborhood Hits	177	Target Neighborhood Hits	96	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX6_HUMAN
NC score	0.965409 (rank : 7)	θ value	4.24587e-58 (rank : 7)
Query Neighborhood Hits	177	Target Neighborhood Hits	97	Shared Neighborhood Hits	84
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
NC score	0.965187 (rank : 8)	θ value	4.24587e-58 (rank : 8)
Query Neighborhood Hits	177	Target Neighborhood Hits	98	Shared Neighborhood Hits	84
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

IF4A2_HUMAN
NC score	0.963405 (rank : 9)	θ value	9.45883e-58 (rank : 9)
Query Neighborhood Hits	177	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
NC score	0.963405 (rank : 10)	θ value	9.45883e-58 (rank : 10)
Query Neighborhood Hits	177	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A1_HUMAN
NC score	0.963082 (rank : 11)	θ value	4.69435e-57 (rank : 13)
Query Neighborhood Hits	177	Target Neighborhood Hits	106	Shared Neighborhood Hits	87
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
NC score	0.963082 (rank : 12)	θ value	4.69435e-57 (rank : 14)
Query Neighborhood Hits	177	Target Neighborhood Hits	106	Shared Neighborhood Hits	87
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

DDX48_HUMAN
NC score	0.962817 (rank : 13)	θ value	3.59435e-57 (rank : 12)
Query Neighborhood Hits	177	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
NC score	0.962763 (rank : 14)	θ value	2.7521e-57 (rank : 11)
Query Neighborhood Hits	177	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DD19A_HUMAN
NC score	0.951941 (rank : 15)	θ value	3.04986e-48 (rank : 16)
Query Neighborhood Hits	177	Target Neighborhood Hits	107	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19B_HUMAN
NC score	0.951669 (rank : 16)	θ value	8.02596e-49 (rank : 15)
Query Neighborhood Hits	177	Target Neighborhood Hits	109	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DD19A_MOUSE
NC score	0.951643 (rank : 17)	θ value	3.04986e-48 (rank : 17)
Query Neighborhood Hits	177	Target Neighborhood Hits	105	Shared Neighborhood Hits	86
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DDX47_MOUSE
NC score	0.949368 (rank : 18)	θ value	4.71619e-41 (rank : 20)
Query Neighborhood Hits	177	Target Neighborhood Hits	97	Shared Neighborhood Hits	84
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX25_HUMAN
NC score	0.949327 (rank : 19)	θ value	2.95404e-43 (rank : 18)
Query Neighborhood Hits	177	Target Neighborhood Hits	93	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX25_MOUSE
NC score	0.948440 (rank : 20)	θ value	3.26607e-42 (rank : 19)
Query Neighborhood Hits	177	Target Neighborhood Hits	98	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX47_HUMAN
NC score	0.948270 (rank : 21)	θ value	6.81017e-40 (rank : 22)
Query Neighborhood Hits	177	Target Neighborhood Hits	97	Shared Neighborhood Hits	84
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX49_MOUSE
NC score	0.945582 (rank : 22)	θ value	3.99248e-40 (rank : 21)
Query Neighborhood Hits	177	Target Neighborhood Hits	119	Shared Neighborhood Hits	88
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX49_HUMAN
NC score	0.940806 (rank : 23)	θ value	4.41421e-39 (rank : 23)
Query Neighborhood Hits	177	Target Neighborhood Hits	223	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX27_MOUSE
NC score	0.940252 (rank : 24)	θ value	6.37413e-38 (rank : 24)
Query Neighborhood Hits	177	Target Neighborhood Hits	174	Shared Neighborhood Hits	88
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_HUMAN
NC score	0.938748 (rank : 25)	θ value	8.32485e-38 (rank : 25)
Query Neighborhood Hits	177	Target Neighborhood Hits	197	Shared Neighborhood Hits	91
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX54_MOUSE
NC score	0.936340 (rank : 26)	θ value	7.29293e-34 (rank : 31)
Query Neighborhood Hits	177	Target Neighborhood Hits	124	Shared Neighborhood Hits	85
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX52_HUMAN
NC score	0.933760 (rank : 27)	θ value	1.85889e-29 (rank : 46)
Query Neighborhood Hits	177	Target Neighborhood Hits	107	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX43_HUMAN
NC score	0.933127 (rank : 28)	θ value	3.16345e-37 (rank : 26)
Query Neighborhood Hits	177	Target Neighborhood Hits	120	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX41_HUMAN
NC score	0.932768 (rank : 29)	θ value	4.72714e-33 (rank : 34)
Query Neighborhood Hits	177	Target Neighborhood Hits	111	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX52_MOUSE
NC score	0.932657 (rank : 30)	θ value	1.57365e-28 (rank : 49)
Query Neighborhood Hits	177	Target Neighborhood Hits	101	Shared Neighborhood Hits	85
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX41_MOUSE
NC score	0.932241 (rank : 31)	θ value	2.77131e-33 (rank : 33)
Query Neighborhood Hits	177	Target Neighborhood Hits	115	Shared Neighborhood Hits	90
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX54_HUMAN
NC score	0.932194 (rank : 32)	θ value	2.34606e-32 (rank : 39)
Query Neighborhood Hits	177	Target Neighborhood Hits	170	Shared Neighborhood Hits	84
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX28_MOUSE
NC score	0.929148 (rank : 33)	θ value	3.07116e-24 (rank : 57)
Query Neighborhood Hits	177	Target Neighborhood Hits	112	Shared Neighborhood Hits	87
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX4_MOUSE
NC score	0.927970 (rank : 34)	θ value	4.00176e-32 (rank : 41)
Query Neighborhood Hits	177	Target Neighborhood Hits	100	Shared Neighborhood Hits	85
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX53_HUMAN
NC score	0.927967 (rank : 35)	θ value	5.584e-34 (rank : 30)
Query Neighborhood Hits	177	Target Neighborhood Hits	124	Shared Neighborhood Hits	81
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX28_HUMAN
NC score	0.926972 (rank : 36)	θ value	6.40375e-22 (rank : 61)
Query Neighborhood Hits	177	Target Neighborhood Hits	103	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX4_HUMAN
NC score	0.926817 (rank : 37)	θ value	5.22648e-32 (rank : 42)
Query Neighborhood Hits	177	Target Neighborhood Hits	123	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX56_HUMAN
NC score	0.926538 (rank : 38)	θ value	2.20094e-22 (rank : 60)
Query Neighborhood Hits	177	Target Neighborhood Hits	77	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DDX55_MOUSE
NC score	0.926150 (rank : 39)	θ value	4.28545e-26 (rank : 54)
Query Neighborhood Hits	177	Target Neighborhood Hits	111	Shared Neighborhood Hits	82
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX55_HUMAN
NC score	0.926134 (rank : 40)	θ value	1.73987e-27 (rank : 50)
Query Neighborhood Hits	177	Target Neighborhood Hits	122	Shared Neighborhood Hits	82
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX56_MOUSE
NC score	0.925748 (rank : 41)	θ value	3.17815e-21 (rank : 62)
Query Neighborhood Hits	177	Target Neighborhood Hits	87	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX17_MOUSE
NC score	0.924943 (rank : 42)	θ value	1.46948e-34 (rank : 29)
Query Neighborhood Hits	177	Target Neighborhood Hits	105	Shared Neighborhood Hits	84
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX17_HUMAN
NC score	0.924821 (rank : 43)	θ value	1.46948e-34 (rank : 28)
Query Neighborhood Hits	177	Target Neighborhood Hits	104	Shared Neighborhood Hits	85
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX18_MOUSE
NC score	0.924029 (rank : 44)	θ value	3.28125e-26 (rank : 53)
Query Neighborhood Hits	177	Target Neighborhood Hits	115	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX10_MOUSE
NC score	0.921980 (rank : 45)	θ value	7.79185e-36 (rank : 27)
Query Neighborhood Hits	177	Target Neighborhood Hits	233	Shared Neighborhood Hits	89
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX18_HUMAN
NC score	0.921108 (rank : 46)	θ value	2.35151e-24 (rank : 55)
Query Neighborhood Hits	177	Target Neighborhood Hits	124	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

PL10_MOUSE
NC score	0.920275 (rank : 47)	θ value	1.79631e-32 (rank : 38)
Query Neighborhood Hits	177	Target Neighborhood Hits	120	Shared Neighborhood Hits	91
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3X_HUMAN
NC score	0.919980 (rank : 48)	θ value	1.37539e-32 (rank : 36)
Query Neighborhood Hits	177	Target Neighborhood Hits	122	Shared Neighborhood Hits	91
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX5_HUMAN
NC score	0.919742 (rank : 49)	θ value	5.40856e-29 (rank : 47)
Query Neighborhood Hits	177	Target Neighborhood Hits	102	Shared Neighborhood Hits	84
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
NC score	0.919692 (rank : 50)	θ value	7.06379e-29 (rank : 48)
Query Neighborhood Hits	177	Target Neighborhood Hits	101	Shared Neighborhood Hits	84
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX3X_MOUSE
NC score	0.919595 (rank : 51)	θ value	1.37539e-32 (rank : 37)
Query Neighborhood Hits	177	Target Neighborhood Hits	117	Shared Neighborhood Hits	91
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX3Y_HUMAN
NC score	0.919413 (rank : 52)	θ value	1.0531e-32 (rank : 35)
Query Neighborhood Hits	177	Target Neighborhood Hits	121	Shared Neighborhood Hits	90
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX10_HUMAN
NC score	0.919301 (rank : 53)	θ value	4.00176e-32 (rank : 40)
Query Neighborhood Hits	177	Target Neighborhood Hits	210	Shared Neighborhood Hits	84
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX3Y_MOUSE
NC score	0.918636 (rank : 54)	θ value	9.8567e-31 (rank : 43)
Query Neighborhood Hits	177	Target Neighborhood Hits	126	Shared Neighborhood Hits	92
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX50_MOUSE
NC score	0.912392 (rank : 55)	θ value	2.35151e-24 (rank : 56)
Query Neighborhood Hits	177	Target Neighborhood Hits	137	Shared Neighborhood Hits	88
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_HUMAN
NC score	0.911599 (rank : 56)	θ value	5.23862e-24 (rank : 58)
Query Neighborhood Hits	177	Target Neighborhood Hits	132	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX46_HUMAN
NC score	0.908426 (rank : 57)	θ value	1.85889e-29 (rank : 44)
Query Neighborhood Hits	177	Target Neighborhood Hits	357	Shared Neighborhood Hits	95
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX31_HUMAN
NC score	0.908051 (rank : 58)	θ value	2.59989e-23 (rank : 59)
Query Neighborhood Hits	177	Target Neighborhood Hits	132	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX23_HUMAN
NC score	0.907490 (rank : 59)	θ value	2.12192e-33 (rank : 32)
Query Neighborhood Hits	177	Target Neighborhood Hits	486	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX46_MOUSE
NC score	0.906627 (rank : 60)	θ value	1.85889e-29 (rank : 45)
Query Neighborhood Hits	177	Target Neighborhood Hits	358	Shared Neighborhood Hits	100
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX21_HUMAN
NC score	0.905521 (rank : 61)	θ value	3.87602e-27 (rank : 51)
Query Neighborhood Hits	177	Target Neighborhood Hits	308	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX24_MOUSE
NC score	0.900362 (rank : 62)	θ value	1.33526e-19 (rank : 63)
Query Neighborhood Hits	177	Target Neighborhood Hits	147	Shared Neighborhood Hits	86
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX21_MOUSE
NC score	0.899193 (rank : 63)	θ value	8.63488e-27 (rank : 52)
Query Neighborhood Hits	177	Target Neighborhood Hits	350	Shared Neighborhood Hits	102
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX51_MOUSE
NC score	0.896624 (rank : 64)	θ value	2.5182e-18 (rank : 68)
Query Neighborhood Hits	177	Target Neighborhood Hits	130	Shared Neighborhood Hits	84
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX24_HUMAN
NC score	0.896185 (rank : 65)	θ value	3.88503e-19 (rank : 64)
Query Neighborhood Hits	177	Target Neighborhood Hits	190	Shared Neighborhood Hits	92
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX51_HUMAN
NC score	0.881474 (rank : 66)	θ value	6.62687e-19 (rank : 65)
Query Neighborhood Hits	177	Target Neighborhood Hits	332	Shared Neighborhood Hits	94
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX1_MOUSE
NC score	0.873147 (rank : 67)	θ value	2.5182e-18 (rank : 67)
Query Neighborhood Hits	177	Target Neighborhood Hits	112	Shared Neighborhood Hits	84
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX1_HUMAN
NC score	0.871908 (rank : 68)	θ value	1.92812e-18 (rank : 66)
Query Neighborhood Hits	177	Target Neighborhood Hits	110	Shared Neighborhood Hits	84
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

RECQ4_HUMAN
NC score	0.517453 (rank : 69)	θ value	0.00665767 (rank : 75)
Query Neighborhood Hits	177	Target Neighborhood Hits	177	Shared Neighborhood Hits	88
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RECQ4_MOUSE
NC score	0.505195 (rank : 70)	θ value	0.00134147 (rank : 73)
Query Neighborhood Hits	177	Target Neighborhood Hits	206	Shared Neighborhood Hits	88
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

BLM_MOUSE
NC score	0.479093 (rank : 71)	θ value	1.43324e-05 (rank : 69)
Query Neighborhood Hits	177	Target Neighborhood Hits	108	Shared Neighborhood Hits	72
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

BLM_HUMAN
NC score	0.463321 (rank : 72)	θ value	9.29e-05 (rank : 70)
Query Neighborhood Hits	177	Target Neighborhood Hits	148	Shared Neighborhood Hits	74
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

WRN_HUMAN
NC score	0.431911 (rank : 73)	θ value	0.279714 (rank : 91)
Query Neighborhood Hits	177	Target Neighborhood Hits	132	Shared Neighborhood Hits	80
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

RECQ5_HUMAN
NC score	0.426346 (rank : 74)	θ value	0.47712 (rank : 97)
Query Neighborhood Hits	177	Target Neighborhood Hits	390	Shared Neighborhood Hits	93
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

FANCM_HUMAN
NC score	0.410098 (rank : 75)	θ value	0.0330416 (rank : 77)
Query Neighborhood Hits	177	Target Neighborhood Hits	210	Shared Neighborhood Hits	80
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

WRN_MOUSE
NC score	0.404485 (rank : 76)	θ value	0.47712 (rank : 99)
Query Neighborhood Hits	177	Target Neighborhood Hits	295	Shared Neighborhood Hits	80
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

FANCM_MOUSE
NC score	0.403114 (rank : 77)	θ value	0.125558 (rank : 80)
Query Neighborhood Hits	177	Target Neighborhood Hits	177	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

DICER_HUMAN
NC score	0.399831 (rank : 78)	θ value	0.00102713 (rank : 72)
Query Neighborhood Hits	177	Target Neighborhood Hits	126	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

DICER_MOUSE
NC score	0.395905 (rank : 79)	θ value	0.00298849 (rank : 74)
Query Neighborhood Hits	177	Target Neighborhood Hits	140	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

RECQ1_HUMAN
NC score	0.389293 (rank : 80)	θ value	5.27518 (rank : 154)
Query Neighborhood Hits	177	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ1_MOUSE
NC score	0.387292 (rank : 81)	θ value	6.88961 (rank : 163)
Query Neighborhood Hits	177	Target Neighborhood Hits	95	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

IFIH1_HUMAN
NC score	0.304202 (rank : 82)	θ value	1.38821 (rank : 116)
Query Neighborhood Hits	177	Target Neighborhood Hits	96	Shared Neighborhood Hits	73
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

LGP2_MOUSE
NC score	0.299150 (rank : 83)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	177	Target Neighborhood Hits	86	Shared Neighborhood Hits	66
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

IFIH1_MOUSE
NC score	0.285202 (rank : 84)	θ value	5.27518 (rank : 149)
Query Neighborhood Hits	177	Target Neighborhood Hits	126	Shared Neighborhood Hits	78
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

LGP2_HUMAN
NC score	0.282574 (rank : 85)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	177	Target Neighborhood Hits	94	Shared Neighborhood Hits	69
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

CC026_HUMAN
NC score	0.193972 (rank : 86)	θ value	1.06291 (rank : 107)
Query Neighborhood Hits	177	Target Neighborhood Hits	39	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

DDX58_MOUSE
NC score	0.173399 (rank : 87)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	177	Target Neighborhood Hits	99	Shared Neighborhood Hits	58
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

CC026_MOUSE
NC score	0.166551 (rank : 88)	θ value	0.279714 (rank : 87)
Query Neighborhood Hits	177	Target Neighborhood Hits	38	Shared Neighborhood Hits	28
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

DDX58_HUMAN
NC score	0.144430 (rank : 89)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	177	Target Neighborhood Hits	105	Shared Neighborhood Hits	55
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

U520_HUMAN
NC score	0.108533 (rank : 90)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	177	Target Neighborhood Hits	88	Shared Neighborhood Hits	42
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

HELC1_HUMAN
NC score	0.084360 (rank : 91)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	177	Target Neighborhood Hits	71	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

SMAL1_HUMAN
NC score	0.075706 (rank : 92)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	177	Target Neighborhood Hits	174	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

CHD4_HUMAN
NC score	0.055053 (rank : 93)	θ value	0.163984 (rank : 81)
Query Neighborhood Hits	177	Target Neighborhood Hits	365	Shared Neighborhood Hits	39
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
NC score	0.054672 (rank : 94)	θ value	0.163984 (rank : 82)
Query Neighborhood Hits	177	Target Neighborhood Hits	408	Shared Neighborhood Hits	42
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

SMAL1_MOUSE
NC score	0.054122 (rank : 95)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	177	Target Neighborhood Hits	157	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

SMCA1_MOUSE
NC score	0.053908 (rank : 96)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	177	Target Neighborhood Hits	117	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

SFRIP_HUMAN
NC score	0.047690 (rank : 97)	θ value	0.47712 (rank : 98)
Query Neighborhood Hits	177	Target Neighborhood Hits	530	Shared Neighborhood Hits	40
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

NCLN_MOUSE
NC score	0.047569 (rank : 98)	θ value	0.0563607 (rank : 78)
Query Neighborhood Hits	177	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VCM8, Q8C7Y4, Q9CX81	Gene names	Ncln
Domain Architecture	No domain graphic available
Description	Nicalin precursor (Nicastrin-like protein).

CHD3_HUMAN
NC score	0.045496 (rank : 99)	θ value	5.27518 (rank : 147)
Query Neighborhood Hits	177	Target Neighborhood Hits	397	Shared Neighborhood Hits	36
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD1_MOUSE
NC score	0.044459 (rank : 100)	θ value	0.21417 (rank : 84)
Query Neighborhood Hits	177	Target Neighborhood Hits	266	Shared Neighborhood Hits	38
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_HUMAN
NC score	0.043873 (rank : 101)	θ value	0.21417 (rank : 83)
Query Neighborhood Hits	177	Target Neighborhood Hits	337	Shared Neighborhood Hits	37
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

NCLN_HUMAN
NC score	0.042936 (rank : 102)	θ value	0.21417 (rank : 85)
Query Neighborhood Hits	177	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q969V3, O75252, Q6FI60, Q6ZMB7, Q8TAT7, Q96H48, Q96IS7, Q9BQH9, Q9BTX4, Q9NPP2	Gene names	NCLN
Domain Architecture	No domain graphic available
Description	Nicalin precursor (Nicastrin-like protein).

NOL8_HUMAN
NC score	0.042204 (rank : 103)	θ value	0.000461057 (rank : 71)
Query Neighborhood Hits	177	Target Neighborhood Hits	297	Shared Neighborhood Hits	27
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

CHD5_HUMAN
NC score	0.040135 (rank : 104)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	177	Target Neighborhood Hits	349	Shared Neighborhood Hits	32
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

IWS1_HUMAN
NC score	0.032558 (rank : 105)	θ value	0.62314 (rank : 102)
Query Neighborhood Hits	177	Target Neighborhood Hits	1241	Shared Neighborhood Hits	65
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

ARI4A_HUMAN
NC score	0.029643 (rank : 106)	θ value	0.365318 (rank : 92)
Query Neighborhood Hits	177	Target Neighborhood Hits	434	Shared Neighborhood Hits	24
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

PPHLN_HUMAN
NC score	0.029456 (rank : 107)	θ value	0.21417 (rank : 86)
Query Neighborhood Hits	177	Target Neighborhood Hits	75	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NEY8, Q86YT2, Q8IXN3, Q8TB09, Q96NB9, Q9NXL4, Q9P0P6, Q9P0R9	Gene names	PPHLN1
Domain Architecture	No domain graphic available
Description	Periphilin-1 (Gastric cancer antigen Ga50).

PPHLN_MOUSE
NC score	0.028710 (rank : 108)	θ value	1.06291 (rank : 109)
Query Neighborhood Hits	177	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2H1, Q8BUZ6	Gene names	Pphln1
Domain Architecture	No domain graphic available
Description	Periphilin-1.

CHD9_MOUSE
NC score	0.026903 (rank : 109)	θ value	2.36792 (rank : 125)
Query Neighborhood Hits	177	Target Neighborhood Hits	427	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

TXND2_HUMAN
NC score	0.026780 (rank : 110)	θ value	0.813845 (rank : 106)
Query Neighborhood Hits	177	Target Neighborhood Hits	793	Shared Neighborhood Hits	48
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

OXR1_MOUSE
NC score	0.026666 (rank : 111)	θ value	0.0252991 (rank : 76)
Query Neighborhood Hits	177	Target Neighborhood Hits	516	Shared Neighborhood Hits	27
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

CJ078_MOUSE
NC score	0.024573 (rank : 112)	θ value	0.365318 (rank : 93)
Query Neighborhood Hits	177	Target Neighborhood Hits	559	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

ENL_HUMAN
NC score	0.024548 (rank : 113)	θ value	0.279714 (rank : 88)
Query Neighborhood Hits	177	Target Neighborhood Hits	305	Shared Neighborhood Hits	22
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

NKTR_HUMAN
NC score	0.023510 (rank : 114)	θ value	1.38821 (rank : 117)
Query Neighborhood Hits	177	Target Neighborhood Hits	658	Shared Neighborhood Hits	48
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

NPM_HUMAN
NC score	0.021799 (rank : 115)	θ value	1.38821 (rank : 118)
Query Neighborhood Hits	177	Target Neighborhood Hits	69	Shared Neighborhood Hits	11
SwissProt Accessions	P06748, P08693, Q12826, Q13440, Q13441, Q14115, Q5EU94, Q5EU95, Q5EU96, Q5EU97, Q5EU98, Q5EU99, Q6V962, Q8WTW5, Q96AT6, Q96DC4, Q96EA5	Gene names	NPM1, NPM
Domain Architecture
Description	Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Numatrin) (Nucleolar protein NO38).

MINT_MOUSE
NC score	0.021130 (rank : 116)	θ value	0.62314 (rank : 103)
Query Neighborhood Hits	177	Target Neighborhood Hits	1514	Shared Neighborhood Hits	58
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

ENKUR_HUMAN
NC score	0.020520 (rank : 117)	θ value	0.47712 (rank : 94)
Query Neighborhood Hits	177	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TC29	Gene names	C10orf63
Domain Architecture	No domain graphic available
Description	Enkurin.

PHF1_HUMAN
NC score	0.020489 (rank : 118)	θ value	0.0563607 (rank : 79)
Query Neighborhood Hits	177	Target Neighborhood Hits	117	Shared Neighborhood Hits	10
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

SRRM2_MOUSE
NC score	0.020468 (rank : 119)	θ value	3.0926 (rank : 134)
Query Neighborhood Hits	177	Target Neighborhood Hits	1470	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CNOT3_HUMAN
NC score	0.019448 (rank : 120)	θ value	0.62314 (rank : 100)
Query Neighborhood Hits	177	Target Neighborhood Hits	425	Shared Neighborhood Hits	14
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CNOT3_MOUSE
NC score	0.018634 (rank : 121)	θ value	0.813845 (rank : 104)
Query Neighborhood Hits	177	Target Neighborhood Hits	504	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

GPTC8_HUMAN
NC score	0.018079 (rank : 122)	θ value	1.38821 (rank : 115)
Query Neighborhood Hits	177	Target Neighborhood Hits	366	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

BCL7A_HUMAN
NC score	0.017405 (rank : 123)	θ value	1.81305 (rank : 120)
Query Neighborhood Hits	177	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q4VC05, Q13843	Gene names	BCL7A
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

EXO1_HUMAN
NC score	0.017088 (rank : 124)	θ value	0.62314 (rank : 101)
Query Neighborhood Hits	177	Target Neighborhood Hits	82	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UQ84, O60545, O75214, O75466, Q5T396, Q96IJ1, Q9UG38, Q9UNW0	Gene names	EXO1, EXOI, HEX1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (hExo1) (Exonuclease I) (hExoI).

CDN1C_MOUSE
NC score	0.016559 (rank : 125)	θ value	1.06291 (rank : 108)
Query Neighborhood Hits	177	Target Neighborhood Hits	161	Shared Neighborhood Hits	8
SwissProt Accessions	P49919	Gene names	Cdkn1c, Kip2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

BCL7A_MOUSE
NC score	0.015669 (rank : 126)	θ value	3.0926 (rank : 131)
Query Neighborhood Hits	177	Target Neighborhood Hits	74	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CXE2, Q8C361, Q8C8M8, Q8VD15	Gene names	Bcl7a
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

K1543_HUMAN
NC score	0.015504 (rank : 127)	θ value	0.47712 (rank : 95)
Query Neighborhood Hits	177	Target Neighborhood Hits	435	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

MINT_HUMAN
NC score	0.015289 (rank : 128)	θ value	2.36792 (rank : 127)
Query Neighborhood Hits	177	Target Neighborhood Hits	1291	Shared Neighborhood Hits	46
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CJ012_HUMAN
NC score	0.014119 (rank : 129)	θ value	5.27518 (rank : 148)
Query Neighborhood Hits	177	Target Neighborhood Hits	467	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

TSH1_MOUSE
NC score	0.014007 (rank : 130)	θ value	1.06291 (rank : 110)
Query Neighborhood Hits	177	Target Neighborhood Hits	675	Shared Neighborhood Hits	22
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

EXOC3_HUMAN
NC score	0.013828 (rank : 131)	θ value	1.38821 (rank : 114)
Query Neighborhood Hits	177	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	O60645, Q8TEN6, Q8WUW0, Q96DI4	Gene names	EXOC3, SEC6, SEC6L1
Domain Architecture
Description	Exocyst complex component 3 (Exocyst complex component Sec6).

TTC14_HUMAN
NC score	0.013667 (rank : 132)	θ value	1.06291 (rank : 111)
Query Neighborhood Hits	177	Target Neighborhood Hits	274	Shared Neighborhood Hits	7
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

SRRM2_HUMAN
NC score	0.013447 (rank : 133)	θ value	6.88961 (rank : 164)
Query Neighborhood Hits	177	Target Neighborhood Hits	1296	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ZCH10_MOUSE
NC score	0.013053 (rank : 134)	θ value	6.88961 (rank : 166)
Query Neighborhood Hits	177	Target Neighborhood Hits	133	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

LMBL3_MOUSE
NC score	0.012695 (rank : 135)	θ value	0.279714 (rank : 89)
Query Neighborhood Hits	177	Target Neighborhood Hits	212	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BLB7, Q641L7, Q6ZPI2, Q8C0G4	Gene names	L3mbtl3
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein).

APC_MOUSE
NC score	0.012275 (rank : 136)	θ value	4.03905 (rank : 137)
Query Neighborhood Hits	177	Target Neighborhood Hits	441	Shared Neighborhood Hits	18
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

APC_HUMAN
NC score	0.011919 (rank : 137)	θ value	4.03905 (rank : 136)
Query Neighborhood Hits	177	Target Neighborhood Hits	603	Shared Neighborhood Hits	28
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

JHD2C_MOUSE
NC score	0.011328 (rank : 138)	θ value	4.03905 (rank : 141)
Query Neighborhood Hits	177	Target Neighborhood Hits	297	Shared Neighborhood Hits	16
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

AKAP2_MOUSE
NC score	0.011226 (rank : 139)	θ value	1.38821 (rank : 112)
Query Neighborhood Hits	177	Target Neighborhood Hits	385	Shared Neighborhood Hits	17
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

TARA_MOUSE
NC score	0.011089 (rank : 140)	θ value	5.27518 (rank : 156)
Query Neighborhood Hits	177	Target Neighborhood Hits	1133	Shared Neighborhood Hits	41
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

RAPH1_HUMAN
NC score	0.011003 (rank : 141)	θ value	0.47712 (rank : 96)
Query Neighborhood Hits	177	Target Neighborhood Hits	593	Shared Neighborhood Hits	22
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

NPDC1_HUMAN
NC score	0.010992 (rank : 142)	θ value	4.03905 (rank : 143)
Query Neighborhood Hits	177	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQX5, Q9BTD6, Q9BXT3, Q9NQS2, Q9Y434	Gene names	NPDC1
Domain Architecture
Description	Neural proliferation differentiation and control protein 1 precursor (NPDC-1 protein).

EMSY_MOUSE
NC score	0.010843 (rank : 143)	θ value	6.88961 (rank : 158)
Query Neighborhood Hits	177	Target Neighborhood Hits	294	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

NKTR_MOUSE
NC score	0.010592 (rank : 144)	θ value	5.27518 (rank : 151)
Query Neighborhood Hits	177	Target Neighborhood Hits	417	Shared Neighborhood Hits	33
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

TAB3_HUMAN
NC score	0.010330 (rank : 145)	θ value	2.36792 (rank : 129)
Query Neighborhood Hits	177	Target Neighborhood Hits	168	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

MECP2_HUMAN
NC score	0.009985 (rank : 146)	θ value	3.0926 (rank : 133)
Query Neighborhood Hits	177	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	P51608, O15233	Gene names	MECP2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

TIRAP_MOUSE
NC score	0.009839 (rank : 147)	θ value	4.03905 (rank : 144)
Query Neighborhood Hits	177	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q99JY1, Q91ZW0	Gene names	Tirap, Mal
Domain Architecture
Description	Toll-interleukin 1 receptor domain-containing adapter protein (TIR domain-containing adapter protein) (MyD88 adapter-like protein) (Adaptor protein Wyatt).

SOCS6_HUMAN
NC score	0.009631 (rank : 148)	θ value	0.813845 (rank : 105)
Query Neighborhood Hits	177	Target Neighborhood Hits	126	Shared Neighborhood Hits	2
SwissProt Accessions	O14544	Gene names	SOCS6, CIS4, SOCS4
Domain Architecture
Description	Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor of cytokine signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4) (CIS-4).

BAZ2A_HUMAN
NC score	0.009388 (rank : 149)	θ value	2.36792 (rank : 124)
Query Neighborhood Hits	177	Target Neighborhood Hits	780	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

SYN3_MOUSE
NC score	0.009175 (rank : 150)	θ value	1.38821 (rank : 119)
Query Neighborhood Hits	177	Target Neighborhood Hits	200	Shared Neighborhood Hits	14
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

CDT1_HUMAN
NC score	0.009092 (rank : 151)	θ value	4.03905 (rank : 139)
Query Neighborhood Hits	177	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H211, Q86XX9, Q96CJ5, Q96GK5, Q96H67, Q96HE6, Q9BWM0	Gene names	CDT1
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP).

NFH_MOUSE
NC score	0.008859 (rank : 152)	θ value	6.88961 (rank : 161)
Query Neighborhood Hits	177	Target Neighborhood Hits	2247	Shared Neighborhood Hits	68
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CO039_HUMAN
NC score	0.008808 (rank : 153)	θ value	3.0926 (rank : 132)
Query Neighborhood Hits	177	Target Neighborhood Hits	264	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

BBX_HUMAN
NC score	0.008482 (rank : 154)	θ value	4.03905 (rank : 138)
Query Neighborhood Hits	177	Target Neighborhood Hits	167	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WY36, Q2TAJ1, Q7L3J8, Q7LBY8, Q8NDB0, Q8WY35, Q9H0J6	Gene names	BBX, HBP2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

TTC28_HUMAN
NC score	0.008422 (rank : 155)	θ value	1.81305 (rank : 122)
Query Neighborhood Hits	177	Target Neighborhood Hits	271	Shared Neighborhood Hits	16
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

PO6F2_MOUSE
NC score	0.008406 (rank : 156)	θ value	0.279714 (rank : 90)
Query Neighborhood Hits	177	Target Neighborhood Hits	639	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

TAB3_MOUSE
NC score	0.008347 (rank : 157)	θ value	6.88961 (rank : 165)
Query Neighborhood Hits	177	Target Neighborhood Hits	273	Shared Neighborhood Hits	11
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

GAB1_MOUSE
NC score	0.008087 (rank : 158)	θ value	2.36792 (rank : 126)
Query Neighborhood Hits	177	Target Neighborhood Hits	233	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

UBQL3_MOUSE
NC score	0.007861 (rank : 159)	θ value	1.81305 (rank : 123)
Query Neighborhood Hits	177	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C5U9	Gene names	Ubqln3
Domain Architecture
Description	Ubiquilin-3.

NCOR1_MOUSE
NC score	0.007543 (rank : 160)	θ value	2.36792 (rank : 128)
Query Neighborhood Hits	177	Target Neighborhood Hits	521	Shared Neighborhood Hits	20
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

BBX_MOUSE
NC score	0.006982 (rank : 161)	θ value	5.27518 (rank : 145)
Query Neighborhood Hits	177	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

DNL1_HUMAN
NC score	0.006582 (rank : 162)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	177	Target Neighborhood Hits	216	Shared Neighborhood Hits	16
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

CMGA_MOUSE
NC score	0.006561 (rank : 163)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	177	Target Neighborhood Hits	172	Shared Neighborhood Hits	9
SwissProt Accessions	P26339	Gene names	Chga
Domain Architecture
Description	Chromogranin A precursor (CgA) [Contains: Pancreastatin; Beta-granin; WE-14].

PO6F2_HUMAN
NC score	0.005817 (rank : 164)	θ value	1.81305 (rank : 121)
Query Neighborhood Hits	177	Target Neighborhood Hits	618	Shared Neighborhood Hits	16
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

JERKY_HUMAN
NC score	0.005603 (rank : 165)	θ value	6.88961 (rank : 160)
Query Neighborhood Hits	177	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	O75564, O75565	Gene names	JRK, JH8
Domain Architecture
Description	Jerky protein homolog.

K2027_HUMAN
NC score	0.005503 (rank : 166)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	177	Target Neighborhood Hits	194	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

LR37A_HUMAN
NC score	0.005270 (rank : 167)	θ value	4.03905 (rank : 142)
Query Neighborhood Hits	177	Target Neighborhood Hits	720	Shared Neighborhood Hits	29
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

BSN_HUMAN
NC score	0.004890 (rank : 168)	θ value	5.27518 (rank : 146)
Query Neighborhood Hits	177	Target Neighborhood Hits	1537	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

NFH_HUMAN
NC score	0.004787 (rank : 169)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	177	Target Neighborhood Hits	1242	Shared Neighborhood Hits	45
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ANR11_HUMAN
NC score	0.004610 (rank : 170)	θ value	4.03905 (rank : 135)
Query Neighborhood Hits	177	Target Neighborhood Hits	1289	Shared Neighborhood Hits	40
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

PHF2_MOUSE
NC score	0.004409 (rank : 171)	θ value	5.27518 (rank : 153)
Query Neighborhood Hits	177	Target Neighborhood Hits	241	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PELI2_HUMAN
NC score	0.004338 (rank : 172)	θ value	5.27518 (rank : 152)
Query Neighborhood Hits	177	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HAT8	Gene names	PELI2
Domain Architecture
Description	Protein pellino homolog 2 (Pellino-2).

UBP8_MOUSE
NC score	0.004313 (rank : 173)	θ value	8.99809 (rank : 177)
Query Neighborhood Hits	177	Target Neighborhood Hits	362	Shared Neighborhood Hits	19
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

MITF_HUMAN
NC score	0.004207 (rank : 174)	θ value	5.27518 (rank : 150)
Query Neighborhood Hits	177	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

TMCC3_MOUSE
NC score	0.003973 (rank : 175)	θ value	5.27518 (rank : 157)
Query Neighborhood Hits	177	Target Neighborhood Hits	192	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R310	Gene names	Tmcc3
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 3.

TRA2A_HUMAN
NC score	0.003450 (rank : 176)	θ value	8.99809 (rank : 175)
Query Neighborhood Hits	177	Target Neighborhood Hits	222	Shared Neighborhood Hits	14
SwissProt Accessions	Q13595	Gene names	TRA2A
Domain Architecture
Description	Transformer-2 protein homolog (TRA-2 alpha).

TRA2A_MOUSE
NC score	0.003428 (rank : 177)	θ value	8.99809 (rank : 176)
Query Neighborhood Hits	177	Target Neighborhood Hits	219	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PFR5	Gene names	Tra2a
Domain Architecture	No domain graphic available
Description	Transformer-2 protein homolog (TRA-2 alpha).

RBMX2_HUMAN
NC score	0.003288 (rank : 178)	θ value	6.88961 (rank : 162)
Query Neighborhood Hits	177	Target Neighborhood Hits	351	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y388, Q5JY82, Q9Y3I8	Gene names	RBMX2
Domain Architecture
Description	RNA-binding motif protein, X-linked 2.

EP300_HUMAN
NC score	0.003271 (rank : 179)	θ value	6.88961 (rank : 159)
Query Neighborhood Hits	177	Target Neighborhood Hits	821	Shared Neighborhood Hits	31
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

EYA4_MOUSE
NC score	0.003050 (rank : 180)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	177	Target Neighborhood Hits	74	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z191	Gene names	Eya4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

CYTSA_HUMAN
NC score	0.003047 (rank : 181)	θ value	1.38821 (rank : 113)
Query Neighborhood Hits	177	Target Neighborhood Hits	1138	Shared Neighborhood Hits	18
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

RBM28_MOUSE
NC score	0.002714 (rank : 182)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	177	Target Neighborhood Hits	368	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CGC6, Q8BG25, Q8VEJ8, Q9CS22, Q9CSE6	Gene names	Rbm28
Domain Architecture	No domain graphic available
Description	RNA-binding protein 28 (RNA-binding motif protein 28).

ABCA2_HUMAN
NC score	0.002344 (rank : 183)	θ value	3.0926 (rank : 130)
Query Neighborhood Hits	177	Target Neighborhood Hits	143	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BZC7	Gene names	ABCA2, ABC2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

RERE_HUMAN
NC score	0.001599 (rank : 184)	θ value	8.99809 (rank : 174)
Query Neighborhood Hits	177	Target Neighborhood Hits	779	Shared Neighborhood Hits	27
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

CYTSA_MOUSE
NC score	0.000799 (rank : 185)	θ value	4.03905 (rank : 140)
Query Neighborhood Hits	177	Target Neighborhood Hits	1104	Shared Neighborhood Hits	18
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

SPEG_MOUSE
NC score	-0.005796 (rank : 186)	θ value	5.27518 (rank : 155)
Query Neighborhood Hits	177	Target Neighborhood Hits	1959	Shared Neighborhood Hits	47
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).