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Network neighborhood for query Sequence : SMAL1_MOUSE

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SMAL1_MOUSE
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SMAL1_HUMAN
θ value	0 (rank : 1)	NC score	0.974336 (rank : 2)
Query Neighborhood Hits	157	Target Neighborhood Hits	174	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

SMAL1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	157	Target Neighborhood Hits	157	Shared Neighborhood Hits	157
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

SMCA5_HUMAN
θ value	8.3442e-30 (rank : 3)	NC score	0.848016 (rank : 4)
Query Neighborhood Hits	157	Target Neighborhood Hits	76	Shared Neighborhood Hits	45
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

SMCA5_MOUSE
θ value	1.85889e-29 (rank : 4)	NC score	0.847820 (rank : 5)
Query Neighborhood Hits	157	Target Neighborhood Hits	80	Shared Neighborhood Hits	46
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

BTAF1_HUMAN
θ value	7.80994e-28 (rank : 5)	NC score	0.849805 (rank : 3)
Query Neighborhood Hits	157	Target Neighborhood Hits	97	Shared Neighborhood Hits	40
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

SMCA2_HUMAN
θ value	7.80994e-28 (rank : 6)	NC score	0.797506 (rank : 22)
Query Neighborhood Hits	157	Target Neighborhood Hits	503	Shared Neighborhood Hits	52
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

CHD6_HUMAN
θ value	1.73987e-27 (rank : 7)	NC score	0.821013 (rank : 13)
Query Neighborhood Hits	157	Target Neighborhood Hits	342	Shared Neighborhood Hits	56
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

SMCA1_MOUSE
θ value	5.06226e-27 (rank : 8)	NC score	0.844496 (rank : 6)
Query Neighborhood Hits	157	Target Neighborhood Hits	117	Shared Neighborhood Hits	51
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

SMCA1_HUMAN
θ value	9.54697e-26 (rank : 9)	NC score	0.843082 (rank : 7)
Query Neighborhood Hits	157	Target Neighborhood Hits	105	Shared Neighborhood Hits	46
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMCA4_HUMAN
θ value	9.54697e-26 (rank : 10)	NC score	0.780899 (rank : 25)
Query Neighborhood Hits	157	Target Neighborhood Hits	597	Shared Neighborhood Hits	60
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SMRCD_MOUSE
θ value	9.54697e-26 (rank : 11)	NC score	0.833836 (rank : 10)
Query Neighborhood Hits	157	Target Neighborhood Hits	96	Shared Neighborhood Hits	37
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

CHD9_HUMAN
θ value	1.24688e-25 (rank : 12)	NC score	0.813652 (rank : 17)
Query Neighborhood Hits	157	Target Neighborhood Hits	343	Shared Neighborhood Hits	53
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CHD9_MOUSE
θ value	2.12685e-25 (rank : 13)	NC score	0.809488 (rank : 20)
Query Neighborhood Hits	157	Target Neighborhood Hits	427	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

CHD8_HUMAN
θ value	4.73814e-25 (rank : 14)	NC score	0.823422 (rank : 12)
Query Neighborhood Hits	157	Target Neighborhood Hits	235	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CHD4_HUMAN
θ value	1.05554e-24 (rank : 15)	NC score	0.767922 (rank : 28)
Query Neighborhood Hits	157	Target Neighborhood Hits	365	Shared Neighborhood Hits	53
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	1.05554e-24 (rank : 16)	NC score	0.765908 (rank : 30)
Query Neighborhood Hits	157	Target Neighborhood Hits	408	Shared Neighborhood Hits	59
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD2_HUMAN
θ value	1.80048e-24 (rank : 17)	NC score	0.817636 (rank : 15)
Query Neighborhood Hits	157	Target Neighborhood Hits	360	Shared Neighborhood Hits	49
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CHD5_HUMAN
θ value	2.35151e-24 (rank : 18)	NC score	0.766322 (rank : 29)
Query Neighborhood Hits	157	Target Neighborhood Hits	349	Shared Neighborhood Hits	54
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

SMRCD_HUMAN
θ value	5.23862e-24 (rank : 19)	NC score	0.841009 (rank : 8)
Query Neighborhood Hits	157	Target Neighborhood Hits	117	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

CHD3_HUMAN
θ value	1.16704e-23 (rank : 20)	NC score	0.768203 (rank : 27)
Query Neighborhood Hits	157	Target Neighborhood Hits	397	Shared Neighborhood Hits	53
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

RA54B_MOUSE
θ value	1.99067e-23 (rank : 21)	NC score	0.835963 (rank : 9)
Query Neighborhood Hits	157	Target Neighborhood Hits	59	Shared Neighborhood Hits	44
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

CHD1_HUMAN
θ value	1.09232e-21 (rank : 22)	NC score	0.809621 (rank : 19)
Query Neighborhood Hits	157	Target Neighborhood Hits	337	Shared Neighborhood Hits	48
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_MOUSE
θ value	1.09232e-21 (rank : 23)	NC score	0.812981 (rank : 18)
Query Neighborhood Hits	157	Target Neighborhood Hits	266	Shared Neighborhood Hits	45
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

RA54B_HUMAN
θ value	1.09232e-21 (rank : 24)	NC score	0.833455 (rank : 11)
Query Neighborhood Hits	157	Target Neighborhood Hits	54	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

ERCC6_HUMAN
θ value	2.7842e-17 (rank : 25)	NC score	0.819575 (rank : 14)
Query Neighborhood Hits	157	Target Neighborhood Hits	247	Shared Neighborhood Hits	42
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

RAD54_HUMAN
θ value	1.16975e-15 (rank : 26)	NC score	0.815469 (rank : 16)
Query Neighborhood Hits	157	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

INOC1_MOUSE
θ value	2.60593e-15 (rank : 27)	NC score	0.792551 (rank : 23)
Query Neighborhood Hits	157	Target Neighborhood Hits	178	Shared Neighborhood Hits	39
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

INOC1_HUMAN
θ value	4.44505e-15 (rank : 28)	NC score	0.792078 (rank : 24)
Query Neighborhood Hits	157	Target Neighborhood Hits	181	Shared Neighborhood Hits	39
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

TTF2_MOUSE
θ value	1.86753e-13 (rank : 29)	NC score	0.737191 (rank : 31)
Query Neighborhood Hits	157	Target Neighborhood Hits	364	Shared Neighborhood Hits	46
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

RAD54_MOUSE
θ value	3.18553e-13 (rank : 30)	NC score	0.806150 (rank : 21)
Query Neighborhood Hits	157	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

TTF2_HUMAN
θ value	4.16044e-13 (rank : 31)	NC score	0.771264 (rank : 26)
Query Neighborhood Hits	157	Target Neighborhood Hits	98	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

SMRA3_HUMAN
θ value	1.74796e-11 (rank : 32)	NC score	0.662872 (rank : 34)
Query Neighborhood Hits	157	Target Neighborhood Hits	265	Shared Neighborhood Hits	37
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

SMRA3_MOUSE
θ value	9.59137e-10 (rank : 33)	NC score	0.661131 (rank : 35)
Query Neighborhood Hits	157	Target Neighborhood Hits	267	Shared Neighborhood Hits	39
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

ATRX_HUMAN
θ value	4.76016e-09 (rank : 34)	NC score	0.596884 (rank : 37)
Query Neighborhood Hits	157	Target Neighborhood Hits	842	Shared Neighborhood Hits	58
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

ATRX_MOUSE
θ value	6.21693e-09 (rank : 35)	NC score	0.611757 (rank : 36)
Query Neighborhood Hits	157	Target Neighborhood Hits	682	Shared Neighborhood Hits	47
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

EP400_MOUSE
θ value	4.45536e-07 (rank : 36)	NC score	0.679718 (rank : 33)
Query Neighborhood Hits	157	Target Neighborhood Hits	592	Shared Neighborhood Hits	61
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

EP400_HUMAN
θ value	3.77169e-06 (rank : 37)	NC score	0.685443 (rank : 32)
Query Neighborhood Hits	157	Target Neighborhood Hits	556	Shared Neighborhood Hits	64
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

DDX41_HUMAN
θ value	0.000270298 (rank : 38)	NC score	0.115144 (rank : 39)
Query Neighborhood Hits	157	Target Neighborhood Hits	111	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
θ value	0.000270298 (rank : 39)	NC score	0.118176 (rank : 38)
Query Neighborhood Hits	157	Target Neighborhood Hits	115	Shared Neighborhood Hits	34
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

TERF2_MOUSE
θ value	0.0193708 (rank : 40)	NC score	0.056012 (rank : 96)
Query Neighborhood Hits	157	Target Neighborhood Hits	128	Shared Neighborhood Hits	11
SwissProt Accessions	O35144	Gene names	Terf2, Trf2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

YETS2_HUMAN
θ value	0.0563607 (rank : 41)	NC score	0.055954 (rank : 97)
Query Neighborhood Hits	157	Target Neighborhood Hits	212	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

DDX23_HUMAN
θ value	0.0736092 (rank : 42)	NC score	0.096145 (rank : 45)
Query Neighborhood Hits	157	Target Neighborhood Hits	486	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX43_HUMAN
θ value	0.0736092 (rank : 43)	NC score	0.067697 (rank : 69)
Query Neighborhood Hits	157	Target Neighborhood Hits	120	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

MEGF9_HUMAN
θ value	0.0961366 (rank : 44)	NC score	0.014587 (rank : 172)
Query Neighborhood Hits	157	Target Neighborhood Hits	557	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

SPHK2_MOUSE
θ value	0.0961366 (rank : 45)	NC score	0.044319 (rank : 132)
Query Neighborhood Hits	157	Target Neighborhood Hits	78	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIA7, Q91VA9, Q9DBH6	Gene names	Sphk2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

ZBTB3_HUMAN
θ value	0.125558 (rank : 46)	NC score	0.006575 (rank : 204)
Query Neighborhood Hits	157	Target Neighborhood Hits	910	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

CIC_HUMAN
θ value	0.163984 (rank : 47)	NC score	0.036270 (rank : 139)
Query Neighborhood Hits	157	Target Neighborhood Hits	992	Shared Neighborhood Hits	48
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

DDX17_HUMAN
θ value	0.163984 (rank : 48)	NC score	0.073219 (rank : 60)
Query Neighborhood Hits	157	Target Neighborhood Hits	104	Shared Neighborhood Hits	19
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX17_MOUSE
θ value	0.163984 (rank : 49)	NC score	0.073229 (rank : 59)
Query Neighborhood Hits	157	Target Neighborhood Hits	105	Shared Neighborhood Hits	19
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

ETV2_MOUSE
θ value	0.163984 (rank : 50)	NC score	0.018830 (rank : 165)
Query Neighborhood Hits	157	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	P41163	Gene names	Etv2, Er71, Etsrp71
Domain Architecture
Description	ETS translocation variant 2 (Ets-related protein 71).

PSD4_MOUSE
θ value	0.163984 (rank : 51)	NC score	0.023608 (rank : 158)
Query Neighborhood Hits	157	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44	Gene names	Psd4
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).

DDX28_HUMAN
θ value	0.21417 (rank : 52)	NC score	0.092335 (rank : 47)
Query Neighborhood Hits	157	Target Neighborhood Hits	103	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX3X_HUMAN
θ value	0.21417 (rank : 53)	NC score	0.106724 (rank : 42)
Query Neighborhood Hits	157	Target Neighborhood Hits	122	Shared Neighborhood Hits	34
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX3X_MOUSE
θ value	0.21417 (rank : 54)	NC score	0.106961 (rank : 41)
Query Neighborhood Hits	157	Target Neighborhood Hits	117	Shared Neighborhood Hits	34
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX3Y_MOUSE
θ value	0.21417 (rank : 55)	NC score	0.094850 (rank : 46)
Query Neighborhood Hits	157	Target Neighborhood Hits	126	Shared Neighborhood Hits	29
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

GLDN_HUMAN
θ value	0.21417 (rank : 56)	NC score	0.025385 (rank : 152)
Query Neighborhood Hits	157	Target Neighborhood Hits	159	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZMI3, Q6UXZ7, Q7Z359	Gene names	GLDN, COLM
Domain Architecture	No domain graphic available
Description	Gliomedin.

IF16_HUMAN
θ value	0.21417 (rank : 57)	NC score	0.028175 (rank : 147)
Query Neighborhood Hits	157	Target Neighborhood Hits	182	Shared Neighborhood Hits	12
SwissProt Accessions	Q16666, Q9UH78	Gene names	IFI16, IFNGIP1
Domain Architecture
Description	Gamma-interferon-inducible protein Ifi-16 (Interferon-inducible myeloid differentiation transcriptional activator) (IFI 16).

MLL4_HUMAN
θ value	0.21417 (rank : 58)	NC score	0.050195 (rank : 128)
Query Neighborhood Hits	157	Target Neighborhood Hits	722	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

PL10_MOUSE
θ value	0.21417 (rank : 59)	NC score	0.110290 (rank : 40)
Query Neighborhood Hits	157	Target Neighborhood Hits	120	Shared Neighborhood Hits	34
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

TGON2_HUMAN
θ value	0.21417 (rank : 60)	NC score	0.082035 (rank : 54)
Query Neighborhood Hits	157	Target Neighborhood Hits	1037	Shared Neighborhood Hits	53
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

ANLN_HUMAN
θ value	0.279714 (rank : 61)	NC score	0.028554 (rank : 145)
Query Neighborhood Hits	157	Target Neighborhood Hits	222	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

M3K14_HUMAN
θ value	0.279714 (rank : 62)	NC score	0.003116 (rank : 213)
Query Neighborhood Hits	157	Target Neighborhood Hits	887	Shared Neighborhood Hits	14
SwissProt Accessions	Q99558, Q8IYN1	Gene names	MAP3K14, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK) (HsNIK).

DDX28_MOUSE
θ value	0.365318 (rank : 63)	NC score	0.089379 (rank : 48)
Query Neighborhood Hits	157	Target Neighborhood Hits	112	Shared Neighborhood Hits	32
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

LIPA3_MOUSE
θ value	0.365318 (rank : 64)	NC score	0.012556 (rank : 186)
Query Neighborhood Hits	157	Target Neighborhood Hits	636	Shared Neighborhood Hits	8
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

WNK4_MOUSE
θ value	0.365318 (rank : 65)	NC score	0.003108 (rank : 214)
Query Neighborhood Hits	157	Target Neighborhood Hits	961	Shared Neighborhood Hits	15
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

YETS2_MOUSE
θ value	0.365318 (rank : 66)	NC score	0.058712 (rank : 85)
Query Neighborhood Hits	157	Target Neighborhood Hits	278	Shared Neighborhood Hits	23
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

BPTF_HUMAN
θ value	0.47712 (rank : 67)	NC score	0.096569 (rank : 44)
Query Neighborhood Hits	157	Target Neighborhood Hits	786	Shared Neighborhood Hits	36
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

MLL2_HUMAN
θ value	0.47712 (rank : 68)	NC score	0.064034 (rank : 73)
Query Neighborhood Hits	157	Target Neighborhood Hits	1788	Shared Neighborhood Hits	53
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PCLO_MOUSE
θ value	0.47712 (rank : 69)	NC score	0.050767 (rank : 124)
Query Neighborhood Hits	157	Target Neighborhood Hits	2275	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

GLDN_MOUSE
θ value	0.62314 (rank : 70)	NC score	0.025565 (rank : 150)
Query Neighborhood Hits	157	Target Neighborhood Hits	155	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BMF8, Q80ZC5	Gene names	Gldn, Crgl2
Domain Architecture	No domain graphic available
Description	Gliomedin (Cancer-related gene liver 2 protein) (CRG-L2).

PANX2_MOUSE
θ value	0.62314 (rank : 71)	NC score	0.027392 (rank : 148)
Query Neighborhood Hits	157	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q6IMP4	Gene names	Panx2
Domain Architecture	No domain graphic available
Description	Pannexin-2.

DLX5_HUMAN
θ value	0.813845 (rank : 72)	NC score	0.011424 (rank : 189)
Query Neighborhood Hits	157	Target Neighborhood Hits	405	Shared Neighborhood Hits	10
SwissProt Accessions	P56178, Q9UPL1	Gene names	DLX5
Domain Architecture
Description	Homeobox protein DLX-5.

UBN1_HUMAN
θ value	0.813845 (rank : 73)	NC score	0.037640 (rank : 135)
Query Neighborhood Hits	157	Target Neighborhood Hits	170	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NPG3, Q13079, Q9P1P7	Gene names	UBN1
Domain Architecture	No domain graphic available
Description	Ubinuclein (Ubiquitously expressed nuclear protein) (VT4).

SPHK2_HUMAN
θ value	1.06291 (rank : 74)	NC score	0.036923 (rank : 136)
Query Neighborhood Hits	157	Target Neighborhood Hits	81	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NRA0, Q9BRN1, Q9H0Q2, Q9NWU7	Gene names	SPHK2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

DDX5_HUMAN
θ value	1.38821 (rank : 75)	NC score	0.069700 (rank : 64)
Query Neighborhood Hits	157	Target Neighborhood Hits	102	Shared Neighborhood Hits	19
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
θ value	1.38821 (rank : 76)	NC score	0.069647 (rank : 65)
Query Neighborhood Hits	157	Target Neighborhood Hits	101	Shared Neighborhood Hits	19
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

ZN219_HUMAN
θ value	1.38821 (rank : 77)	NC score	0.000887 (rank : 221)
Query Neighborhood Hits	157	Target Neighborhood Hits	876	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

ZN438_HUMAN
θ value	1.38821 (rank : 78)	NC score	0.004153 (rank : 210)
Query Neighborhood Hits	157	Target Neighborhood Hits	906	Shared Neighborhood Hits	21
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

BAG3_HUMAN
θ value	1.81305 (rank : 79)	NC score	0.029946 (rank : 142)
Query Neighborhood Hits	157	Target Neighborhood Hits	314	Shared Neighborhood Hits	28
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

DDX3Y_HUMAN
θ value	1.81305 (rank : 80)	NC score	0.100917 (rank : 43)
Query Neighborhood Hits	157	Target Neighborhood Hits	121	Shared Neighborhood Hits	34
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX4_HUMAN
θ value	1.81305 (rank : 81)	NC score	0.070005 (rank : 63)
Query Neighborhood Hits	157	Target Neighborhood Hits	123	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

NUFP1_HUMAN
θ value	1.81305 (rank : 82)	NC score	0.023950 (rank : 156)
Query Neighborhood Hits	157	Target Neighborhood Hits	193	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UHK0, Q8WVM5, Q96SG1	Gene names	NUFIP1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

PRG4_HUMAN
θ value	1.81305 (rank : 83)	NC score	0.023889 (rank : 157)
Query Neighborhood Hits	157	Target Neighborhood Hits	764	Shared Neighborhood Hits	39
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

WNK1_MOUSE
θ value	1.81305 (rank : 84)	NC score	0.005424 (rank : 207)
Query Neighborhood Hits	157	Target Neighborhood Hits	1179	Shared Neighborhood Hits	33
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

DDX4_MOUSE
θ value	2.36792 (rank : 85)	NC score	0.070425 (rank : 62)
Query Neighborhood Hits	157	Target Neighborhood Hits	100	Shared Neighborhood Hits	23
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DOS_HUMAN
θ value	2.36792 (rank : 86)	NC score	0.028809 (rank : 143)
Query Neighborhood Hits	157	Target Neighborhood Hits	68	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N350, O43385	Gene names	DOS, C19orf26
Domain Architecture	No domain graphic available
Description	Protein Dos.

MUC5B_HUMAN
θ value	2.36792 (rank : 87)	NC score	0.013676 (rank : 181)
Query Neighborhood Hits	157	Target Neighborhood Hits	1020	Shared Neighborhood Hits	40
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

PRDM2_HUMAN
θ value	2.36792 (rank : 88)	NC score	0.003589 (rank : 212)
Query Neighborhood Hits	157	Target Neighborhood Hits	1135	Shared Neighborhood Hits	26
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

SEN34_MOUSE
θ value	2.36792 (rank : 89)	NC score	0.019590 (rank : 163)
Query Neighborhood Hits	157	Target Neighborhood Hits	158	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BMZ5, Q58EU2, Q99LV6, Q9CYW1	Gene names	Tsen34, Leng5, Sen34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (Leukocyte receptor cluster member 5 homolog).

TXND2_HUMAN
θ value	2.36792 (rank : 90)	NC score	0.036780 (rank : 137)
Query Neighborhood Hits	157	Target Neighborhood Hits	793	Shared Neighborhood Hits	36
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

COAA1_MOUSE
θ value	3.0926 (rank : 91)	NC score	0.006890 (rank : 202)
Query Neighborhood Hits	157	Target Neighborhood Hits	286	Shared Neighborhood Hits	11
SwissProt Accessions	Q05306	Gene names	Col10a1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

EPHB2_HUMAN
θ value	3.0926 (rank : 92)	NC score	-0.001807 (rank : 224)
Query Neighborhood Hits	157	Target Neighborhood Hits	983	Shared Neighborhood Hits	7
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
θ value	3.0926 (rank : 93)	NC score	-0.001816 (rank : 225)
Query Neighborhood Hits	157	Target Neighborhood Hits	982	Shared Neighborhood Hits	7
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

FIBA_HUMAN
θ value	3.0926 (rank : 94)	NC score	0.005794 (rank : 206)
Query Neighborhood Hits	157	Target Neighborhood Hits	132	Shared Neighborhood Hits	3
SwissProt Accessions	P02671, Q9BX62, Q9UCH2	Gene names	FGA
Domain Architecture
Description	Fibrinogen alpha chain precursor [Contains: Fibrinopeptide A].

GA2L1_MOUSE
θ value	3.0926 (rank : 95)	NC score	0.014873 (rank : 171)
Query Neighborhood Hits	157	Target Neighborhood Hits	114	Shared Neighborhood Hits	9
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

GASP2_MOUSE
θ value	3.0926 (rank : 96)	NC score	0.014335 (rank : 177)
Query Neighborhood Hits	157	Target Neighborhood Hits	228	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BUY8	Gene names	Gprasp2
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 2 (GASP-2).

HS74L_HUMAN
θ value	3.0926 (rank : 97)	NC score	0.008964 (rank : 195)
Query Neighborhood Hits	157	Target Neighborhood Hits	141	Shared Neighborhood Hits	4
SwissProt Accessions	O95757, Q4W5M5, Q8IWA2	Gene names	HSPA4L, APG1, OSP94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

K1802_MOUSE
θ value	3.0926 (rank : 98)	NC score	0.033915 (rank : 141)
Query Neighborhood Hits	157	Target Neighborhood Hits	1596	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

SETBP_MOUSE
θ value	3.0926 (rank : 99)	NC score	0.035981 (rank : 140)
Query Neighborhood Hits	157	Target Neighborhood Hits	352	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

ACM4_MOUSE
θ value	4.03905 (rank : 100)	NC score	-0.002875 (rank : 226)
Query Neighborhood Hits	157	Target Neighborhood Hits	894	Shared Neighborhood Hits	5
SwissProt Accessions	P32211, Q64056	Gene names	Chrm4, Chrm-4
Domain Architecture
Description	Muscarinic acetylcholine receptor M4 (Mm4 mAChR).

AFF4_HUMAN
θ value	4.03905 (rank : 101)	NC score	0.042007 (rank : 133)
Query Neighborhood Hits	157	Target Neighborhood Hits	611	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

CARD6_HUMAN
θ value	4.03905 (rank : 102)	NC score	0.023354 (rank : 159)
Query Neighborhood Hits	157	Target Neighborhood Hits	145	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BX69	Gene names	CARD6
Domain Architecture
Description	Caspase recruitment domain-containing protein 6.

CIC_MOUSE
θ value	4.03905 (rank : 103)	NC score	0.022084 (rank : 161)
Query Neighborhood Hits	157	Target Neighborhood Hits	742	Shared Neighborhood Hits	35
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

DLX5_MOUSE
θ value	4.03905 (rank : 104)	NC score	0.008470 (rank : 199)
Query Neighborhood Hits	157	Target Neighborhood Hits	434	Shared Neighborhood Hits	11
SwissProt Accessions	P70396, O54876, O54877, O54878, Q9JJ45	Gene names	Dlx5
Domain Architecture
Description	Homeobox protein DLX-5.

FATH_HUMAN
θ value	4.03905 (rank : 105)	NC score	-0.000215 (rank : 223)
Query Neighborhood Hits	157	Target Neighborhood Hits	570	Shared Neighborhood Hits	6
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

HS74L_MOUSE
θ value	4.03905 (rank : 106)	NC score	0.008477 (rank : 198)
Query Neighborhood Hits	157	Target Neighborhood Hits	141	Shared Neighborhood Hits	5
SwissProt Accessions	P48722, P97854, Q8BQD0, Q8CC45, Q91X29	Gene names	Hspa4l, Apg1, Hsp4l, Osp94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

MYT1_HUMAN
θ value	4.03905 (rank : 107)	NC score	0.012929 (rank : 183)
Query Neighborhood Hits	157	Target Neighborhood Hits	475	Shared Neighborhood Hits	11
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

RIN2_MOUSE
θ value	4.03905 (rank : 108)	NC score	0.024352 (rank : 155)
Query Neighborhood Hits	157	Target Neighborhood Hits	72	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D684, Q99K06	Gene names	Rin2
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2).

SYN1_HUMAN
θ value	4.03905 (rank : 109)	NC score	0.025438 (rank : 151)
Query Neighborhood Hits	157	Target Neighborhood Hits	419	Shared Neighborhood Hits	25
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

BAG3_MOUSE
θ value	5.27518 (rank : 110)	NC score	0.036595 (rank : 138)
Query Neighborhood Hits	157	Target Neighborhood Hits	513	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BAI1_HUMAN
θ value	5.27518 (rank : 111)	NC score	0.001870 (rank : 218)
Query Neighborhood Hits	157	Target Neighborhood Hits	375	Shared Neighborhood Hits	8
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

CLN3_MOUSE
θ value	5.27518 (rank : 112)	NC score	0.013805 (rank : 180)
Query Neighborhood Hits	157	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q61124, P70400	Gene names	Cln3
Domain Architecture
Description	Protein CLN3 (Battenin).

FYB_MOUSE
θ value	5.27518 (rank : 113)	NC score	0.014576 (rank : 174)
Query Neighborhood Hits	157	Target Neighborhood Hits	194	Shared Neighborhood Hits	13
SwissProt Accessions	O35601, Q9Z2H3	Gene names	Fyb
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

MYT1_MOUSE
θ value	5.27518 (rank : 114)	NC score	0.012493 (rank : 187)
Query Neighborhood Hits	157	Target Neighborhood Hits	385	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

PCLO_HUMAN
θ value	5.27518 (rank : 115)	NC score	0.038458 (rank : 134)
Query Neighborhood Hits	157	Target Neighborhood Hits	2046	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

R3HD1_HUMAN
θ value	5.27518 (rank : 116)	NC score	0.019535 (rank : 164)
Query Neighborhood Hits	157	Target Neighborhood Hits	203	Shared Neighborhood Hits	13
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

SETBP_HUMAN
θ value	5.27518 (rank : 117)	NC score	0.028549 (rank : 146)
Query Neighborhood Hits	157	Target Neighborhood Hits	305	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

TAF6_MOUSE
θ value	5.27518 (rank : 118)	NC score	0.015616 (rank : 170)
Query Neighborhood Hits	157	Target Neighborhood Hits	110	Shared Neighborhood Hits	8
SwissProt Accessions	Q62311	Gene names	Taf6, Taf2e
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80) (p80).

AFF1_HUMAN
θ value	6.88961 (rank : 119)	NC score	0.028679 (rank : 144)
Query Neighborhood Hits	157	Target Neighborhood Hits	506	Shared Neighborhood Hits	27
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

ARI1A_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.022466 (rank : 160)
Query Neighborhood Hits	157	Target Neighborhood Hits	787	Shared Neighborhood Hits	38
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

BAT2_MOUSE
θ value	6.88961 (rank : 121)	NC score	0.024359 (rank : 154)
Query Neighborhood Hits	157	Target Neighborhood Hits	947	Shared Neighborhood Hits	53
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CO1A1_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.006417 (rank : 205)
Query Neighborhood Hits	157	Target Neighborhood Hits	475	Shared Neighborhood Hits	20
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CRTAP_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.009875 (rank : 192)
Query Neighborhood Hits	157	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	O75718	Gene names	CRTAP, CASP
Domain Architecture	No domain graphic available
Description	Cartilage-associated protein precursor.

DEN1A_MOUSE
θ value	6.88961 (rank : 124)	NC score	0.008861 (rank : 197)
Query Neighborhood Hits	157	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

DHX9_MOUSE
θ value	6.88961 (rank : 125)	NC score	0.003651 (rank : 211)
Query Neighborhood Hits	157	Target Neighborhood Hits	72	Shared Neighborhood Hits	3
SwissProt Accessions	O70133, O35931, O54703, Q5FWY1, Q6R5F7, Q9CSA2	Gene names	Dhx9, Ddx9
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9) (mHEL-5).

EP300_HUMAN
θ value	6.88961 (rank : 126)	NC score	0.026038 (rank : 149)
Query Neighborhood Hits	157	Target Neighborhood Hits	821	Shared Neighborhood Hits	47
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

GA2L2_MOUSE
θ value	6.88961 (rank : 127)	NC score	0.020506 (rank : 162)
Query Neighborhood Hits	157	Target Neighborhood Hits	395	Shared Neighborhood Hits	29
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

HSH2D_HUMAN
θ value	6.88961 (rank : 128)	NC score	0.011251 (rank : 190)
Query Neighborhood Hits	157	Target Neighborhood Hits	159	Shared Neighborhood Hits	5
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

LTBP4_MOUSE
θ value	6.88961 (rank : 129)	NC score	0.000842 (rank : 222)
Query Neighborhood Hits	157	Target Neighborhood Hits	607	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

NU214_HUMAN
θ value	6.88961 (rank : 130)	NC score	0.016079 (rank : 169)
Query Neighborhood Hits	157	Target Neighborhood Hits	657	Shared Neighborhood Hits	34
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

RIN3_HUMAN
θ value	6.88961 (rank : 131)	NC score	0.017622 (rank : 167)
Query Neighborhood Hits	157	Target Neighborhood Hits	227	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

SYN2_HUMAN
θ value	6.88961 (rank : 132)	NC score	0.014482 (rank : 175)
Query Neighborhood Hits	157	Target Neighborhood Hits	213	Shared Neighborhood Hits	13
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

SYP2L_HUMAN
θ value	6.88961 (rank : 133)	NC score	0.006846 (rank : 203)
Query Neighborhood Hits	157	Target Neighborhood Hits	400	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TCRG1_HUMAN
θ value	6.88961 (rank : 134)	NC score	0.014040 (rank : 179)
Query Neighborhood Hits	157	Target Neighborhood Hits	929	Shared Neighborhood Hits	26
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	6.88961 (rank : 135)	NC score	0.014201 (rank : 178)
Query Neighborhood Hits	157	Target Neighborhood Hits	947	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

WASF2_MOUSE
θ value	6.88961 (rank : 136)	NC score	0.009407 (rank : 193)
Query Neighborhood Hits	157	Target Neighborhood Hits	315	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

2A5D_HUMAN
θ value	8.99809 (rank : 137)	NC score	0.004212 (rank : 209)
Query Neighborhood Hits	157	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	Q14738, O00494, O00696, Q15171	Gene names	PPP2R5D
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A, B subunit, B' delta isoform) (PP2A, B subunit, B56 delta isoform) (PP2A, B subunit, PR61 delta isoform) (PP2A, B subunit, R5 delta isoform).

ALMS1_HUMAN
θ value	8.99809 (rank : 138)	NC score	0.017649 (rank : 166)
Query Neighborhood Hits	157	Target Neighborhood Hits	356	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

CAC1G_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.008894 (rank : 196)
Query Neighborhood Hits	157	Target Neighborhood Hits	587	Shared Neighborhood Hits	32
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CHAC1_MOUSE
θ value	8.99809 (rank : 140)	NC score	0.010485 (rank : 191)
Query Neighborhood Hits	157	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R3J5, Q9D944	Gene names	Chac1
Domain Architecture	No domain graphic available
Description	Cation transport regulator-like protein 1.

COIA1_HUMAN
θ value	8.99809 (rank : 141)	NC score	0.007678 (rank : 201)
Query Neighborhood Hits	157	Target Neighborhood Hits	447	Shared Neighborhood Hits	23
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CRTAP_MOUSE
θ value	8.99809 (rank : 142)	NC score	0.009228 (rank : 194)
Query Neighborhood Hits	157	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CYD3, O88698	Gene names	Crtap, Casp
Domain Architecture	No domain graphic available
Description	Cartilage-associated protein precursor.

GGA3_HUMAN
θ value	8.99809 (rank : 143)	NC score	0.005341 (rank : 208)
Query Neighborhood Hits	157	Target Neighborhood Hits	127	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NZ52, Q15017, Q6IS16, Q9UJY3	Gene names	GGA3, KIAA0154
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

GON4L_MOUSE
θ value	8.99809 (rank : 144)	NC score	0.014579 (rank : 173)
Query Neighborhood Hits	157	Target Neighborhood Hits	455	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

HERC2_HUMAN
θ value	8.99809 (rank : 145)	NC score	0.002805 (rank : 217)
Query Neighborhood Hits	157	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HLX1_MOUSE
θ value	8.99809 (rank : 146)	NC score	0.001036 (rank : 220)
Query Neighborhood Hits	157	Target Neighborhood Hits	362	Shared Neighborhood Hits	5
SwissProt Accessions	Q61670	Gene names	Hlx1, Hlx
Domain Architecture
Description	Homeobox protein HLX1.

IRS1_HUMAN
θ value	8.99809 (rank : 147)	NC score	0.013210 (rank : 182)
Query Neighborhood Hits	157	Target Neighborhood Hits	109	Shared Neighborhood Hits	5
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

MMP24_HUMAN
θ value	8.99809 (rank : 148)	NC score	0.003004 (rank : 216)
Query Neighborhood Hits	157	Target Neighborhood Hits	66	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5R2, Q9H440	Gene names	MMP24, MT5MMP
Domain Architecture
Description	Matrix metalloproteinase-24 precursor (EC 3.4.24.-) (MMP-24) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP).

MMP24_MOUSE
θ value	8.99809 (rank : 149)	NC score	0.003014 (rank : 215)
Query Neighborhood Hits	157	Target Neighborhood Hits	71	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R0S2, Q9Z0J9	Gene names	Mmp24, Mmp21, Mt5mmp
Domain Architecture
Description	Matrix metalloproteinase-24 precursor (EC 3.4.24.-) (MMP-24) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP) (MMP-21).

MUCDL_MOUSE
θ value	8.99809 (rank : 150)	NC score	0.011766 (rank : 188)
Query Neighborhood Hits	157	Target Neighborhood Hits	461	Shared Neighborhood Hits	26
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NCA11_MOUSE
θ value	8.99809 (rank : 151)	NC score	0.001463 (rank : 219)
Query Neighborhood Hits	157	Target Neighborhood Hits	661	Shared Neighborhood Hits	17
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

RIMB1_HUMAN
θ value	8.99809 (rank : 152)	NC score	0.007991 (rank : 200)
Query Neighborhood Hits	157	Target Neighborhood Hits	1479	Shared Neighborhood Hits	30
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SGIP1_HUMAN
θ value	8.99809 (rank : 153)	NC score	0.012604 (rank : 185)
Query Neighborhood Hits	157	Target Neighborhood Hits	198	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SYN1_MOUSE
θ value	8.99809 (rank : 154)	NC score	0.024507 (rank : 153)
Query Neighborhood Hits	157	Target Neighborhood Hits	363	Shared Neighborhood Hits	21
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

TAF6_HUMAN
θ value	8.99809 (rank : 155)	NC score	0.014372 (rank : 176)
Query Neighborhood Hits	157	Target Neighborhood Hits	127	Shared Neighborhood Hits	10
SwissProt Accessions	P49848	Gene names	TAF6, TAF2E, TAFII70
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80).

TULP4_HUMAN
θ value	8.99809 (rank : 156)	NC score	0.017490 (rank : 168)
Query Neighborhood Hits	157	Target Neighborhood Hits	426	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

TULP4_MOUSE
θ value	8.99809 (rank : 157)	NC score	0.012751 (rank : 184)
Query Neighborhood Hits	157	Target Neighborhood Hits	247	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

AIRE_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.087058 (rank : 50)
Query Neighborhood Hits	157	Target Neighborhood Hits	144	Shared Neighborhood Hits	12
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.088529 (rank : 49)
Query Neighborhood Hits	157	Target Neighborhood Hits	196	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

BAZ1A_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.063179 (rank : 75)
Query Neighborhood Hits	157	Target Neighborhood Hits	693	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ1B_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.061316 (rank : 79)
Query Neighborhood Hits	157	Target Neighborhood Hits	701	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ1B_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.069132 (rank : 67)
Query Neighborhood Hits	157	Target Neighborhood Hits	394	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BAZ2A_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.052749 (rank : 116)
Query Neighborhood Hits	157	Target Neighborhood Hits	744	Shared Neighborhood Hits	36
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BAZ2B_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.050910 (rank : 121)
Query Neighborhood Hits	157	Target Neighborhood Hits	803	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

CBX1_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.056163 (rank : 94)
Query Neighborhood Hits	157	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.056163 (rank : 95)
Query Neighborhood Hits	157	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

CBX3_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.051701 (rank : 117)
Query Neighborhood Hits	157	Target Neighborhood Hits	39	Shared Neighborhood Hits	12
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

CBX5_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.068004 (rank : 68)
Query Neighborhood Hits	157	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CBX5_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.060013 (rank : 81)
Query Neighborhood Hits	157	Target Neighborhood Hits	67	Shared Neighborhood Hits	10
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

CBX7_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.050843 (rank : 123)
Query Neighborhood Hits	157	Target Neighborhood Hits	38	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VDS3	Gene names	Cbx7, D15Ertd417e
Domain Architecture
Description	Chromobox protein homolog 7.

DD19A_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.055758 (rank : 101)
Query Neighborhood Hits	157	Target Neighborhood Hits	107	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19A_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.055529 (rank : 105)
Query Neighborhood Hits	157	Target Neighborhood Hits	105	Shared Neighborhood Hits	28
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DD19B_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.055566 (rank : 104)
Query Neighborhood Hits	157	Target Neighborhood Hits	109	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DDX20_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.051042 (rank : 120)
Query Neighborhood Hits	157	Target Neighborhood Hits	121	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX20_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.054122 (rank : 110)
Query Neighborhood Hits	157	Target Neighborhood Hits	177	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX21_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.050868 (rank : 122)
Query Neighborhood Hits	157	Target Neighborhood Hits	350	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX25_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.056611 (rank : 91)
Query Neighborhood Hits	157	Target Neighborhood Hits	98	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX27_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.051353 (rank : 119)
Query Neighborhood Hits	157	Target Neighborhood Hits	197	Shared Neighborhood Hits	23
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.050745 (rank : 125)
Query Neighborhood Hits	157	Target Neighborhood Hits	174	Shared Neighborhood Hits	22
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX31_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.054674 (rank : 107)
Query Neighborhood Hits	157	Target Neighborhood Hits	132	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX46_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.056794 (rank : 90)
Query Neighborhood Hits	157	Target Neighborhood Hits	357	Shared Neighborhood Hits	25
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.056530 (rank : 92)
Query Neighborhood Hits	157	Target Neighborhood Hits	358	Shared Neighborhood Hits	25
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX47_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.055686 (rank : 103)
Query Neighborhood Hits	157	Target Neighborhood Hits	97	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.053627 (rank : 114)
Query Neighborhood Hits	157	Target Neighborhood Hits	97	Shared Neighborhood Hits	21
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX48_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.055859 (rank : 98)
Query Neighborhood Hits	157	Target Neighborhood Hits	102	Shared Neighborhood Hits	24
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.055833 (rank : 99)
Query Neighborhood Hits	157	Target Neighborhood Hits	102	Shared Neighborhood Hits	24
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX49_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.055795 (rank : 100)
Query Neighborhood Hits	157	Target Neighborhood Hits	223	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX49_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.059109 (rank : 84)
Query Neighborhood Hits	157	Target Neighborhood Hits	119	Shared Neighborhood Hits	24
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX52_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.050744 (rank : 126)
Query Neighborhood Hits	157	Target Neighborhood Hits	107	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX53_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.056189 (rank : 93)
Query Neighborhood Hits	157	Target Neighborhood Hits	124	Shared Neighborhood Hits	19
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DPF1_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.050719 (rank : 127)
Query Neighborhood Hits	157	Target Neighborhood Hits	136	Shared Neighborhood Hits	7
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

FANCM_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.054645 (rank : 108)
Query Neighborhood Hits	157	Target Neighborhood Hits	210	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

IF4A2_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.050076 (rank : 129)
Query Neighborhood Hits	157	Target Neighborhood Hits	102	Shared Neighborhood Hits	21
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.050076 (rank : 130)
Query Neighborhood Hits	157	Target Neighborhood Hits	102	Shared Neighborhood Hits	21
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IWS1_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.058264 (rank : 86)
Query Neighborhood Hits	157	Target Neighborhood Hits	1241	Shared Neighborhood Hits	44
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.065984 (rank : 72)
Query Neighborhood Hits	157	Target Neighborhood Hits	1258	Shared Neighborhood Hits	46
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LEO1_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.053956 (rank : 113)
Query Neighborhood Hits	157	Target Neighborhood Hits	958	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LEO1_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.055746 (rank : 102)
Query Neighborhood Hits	157	Target Neighborhood Hits	946	Shared Neighborhood Hits	33
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LY10_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.059155 (rank : 83)
Query Neighborhood Hits	157	Target Neighborhood Hits	151	Shared Neighborhood Hits	11
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

MLL3_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.057555 (rank : 89)
Query Neighborhood Hits	157	Target Neighborhood Hits	1644	Shared Neighborhood Hits	61
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.054006 (rank : 111)
Query Neighborhood Hits	157	Target Neighborhood Hits	1399	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NIPBL_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.058019 (rank : 88)
Query Neighborhood Hits	157	Target Neighborhood Hits	1311	Shared Neighborhood Hits	43
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.054528 (rank : 109)
Query Neighborhood Hits	157	Target Neighborhood Hits	1041	Shared Neighborhood Hits	44
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NSD1_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.058058 (rank : 87)
Query Neighborhood Hits	157	Target Neighborhood Hits	427	Shared Neighborhood Hits	23
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.060411 (rank : 80)
Query Neighborhood Hits	157	Target Neighborhood Hits	472	Shared Neighborhood Hits	28
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PB1_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.052981 (rank : 115)
Query Neighborhood Hits	157	Target Neighborhood Hits	261	Shared Neighborhood Hits	10
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

PF21A_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.076334 (rank : 57)
Query Neighborhood Hits	157	Target Neighborhood Hits	303	Shared Neighborhood Hits	16
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.075750 (rank : 58)
Query Neighborhood Hits	157	Target Neighborhood Hits	285	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21B_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.077235 (rank : 55)
Query Neighborhood Hits	157	Target Neighborhood Hits	197	Shared Neighborhood Hits	12
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.082155 (rank : 53)
Query Neighborhood Hits	157	Target Neighborhood Hits	278	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF12_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.082361 (rank : 51)
Query Neighborhood Hits	157	Target Neighborhood Hits	174	Shared Neighborhood Hits	14
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.082329 (rank : 52)
Query Neighborhood Hits	157	Target Neighborhood Hits	172	Shared Neighborhood Hits	12
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PKCB1_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.077225 (rank : 56)
Query Neighborhood Hits	157	Target Neighborhood Hits	488	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

RBBP6_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.051365 (rank : 118)
Query Neighborhood Hits	157	Target Neighborhood Hits	1135	Shared Neighborhood Hits	37
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RSF1_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.067520 (rank : 70)
Query Neighborhood Hits	157	Target Neighborhood Hits	539	Shared Neighborhood Hits	24
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SP110_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.066201 (rank : 71)
Query Neighborhood Hits	157	Target Neighborhood Hits	141	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

TIF1A_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.059418 (rank : 82)
Query Neighborhood Hits	157	Target Neighborhood Hits	327	Shared Neighborhood Hits	15
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1A_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.062628 (rank : 76)
Query Neighborhood Hits	157	Target Neighborhood Hits	307	Shared Neighborhood Hits	17
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1G_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.055485 (rank : 106)
Query Neighborhood Hits	157	Target Neighborhood Hits	410	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.061375 (rank : 78)
Query Neighborhood Hits	157	Target Neighborhood Hits	498	Shared Neighborhood Hits	21
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TRI66_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.063606 (rank : 74)
Query Neighborhood Hits	157	Target Neighborhood Hits	479	Shared Neighborhood Hits	32
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.061611 (rank : 77)
Query Neighborhood Hits	157	Target Neighborhood Hits	491	Shared Neighborhood Hits	27
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TXND2_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.053976 (rank : 112)
Query Neighborhood Hits	157	Target Neighborhood Hits	828	Shared Neighborhood Hits	33
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

UHRF2_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.050053 (rank : 131)
Query Neighborhood Hits	157	Target Neighborhood Hits	269	Shared Neighborhood Hits	11
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

ZMY11_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.071151 (rank : 61)
Query Neighborhood Hits	157	Target Neighborhood Hits	201	Shared Neighborhood Hits	12
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

ZMY11_MOUSE
θ value	θ > 10 (rank : 226)	NC score	0.069391 (rank : 66)
Query Neighborhood Hits	157	Target Neighborhood Hits	198	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

Hits sorted by NC score

SMAL1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	157	Target Neighborhood Hits	157	Shared Neighborhood Hits	157
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

SMAL1_HUMAN
NC score	0.974336 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	157	Target Neighborhood Hits	174	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

BTAF1_HUMAN
NC score	0.849805 (rank : 3)	θ value	7.80994e-28 (rank : 5)
Query Neighborhood Hits	157	Target Neighborhood Hits	97	Shared Neighborhood Hits	40
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

SMCA5_HUMAN
NC score	0.848016 (rank : 4)	θ value	8.3442e-30 (rank : 3)
Query Neighborhood Hits	157	Target Neighborhood Hits	76	Shared Neighborhood Hits	45
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

SMCA5_MOUSE
NC score	0.847820 (rank : 5)	θ value	1.85889e-29 (rank : 4)
Query Neighborhood Hits	157	Target Neighborhood Hits	80	Shared Neighborhood Hits	46
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

SMCA1_MOUSE
NC score	0.844496 (rank : 6)	θ value	5.06226e-27 (rank : 8)
Query Neighborhood Hits	157	Target Neighborhood Hits	117	Shared Neighborhood Hits	51
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

SMCA1_HUMAN
NC score	0.843082 (rank : 7)	θ value	9.54697e-26 (rank : 9)
Query Neighborhood Hits	157	Target Neighborhood Hits	105	Shared Neighborhood Hits	46
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMRCD_HUMAN
NC score	0.841009 (rank : 8)	θ value	5.23862e-24 (rank : 19)
Query Neighborhood Hits	157	Target Neighborhood Hits	117	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

RA54B_MOUSE
NC score	0.835963 (rank : 9)	θ value	1.99067e-23 (rank : 21)
Query Neighborhood Hits	157	Target Neighborhood Hits	59	Shared Neighborhood Hits	44
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

SMRCD_MOUSE
NC score	0.833836 (rank : 10)	θ value	9.54697e-26 (rank : 11)
Query Neighborhood Hits	157	Target Neighborhood Hits	96	Shared Neighborhood Hits	37
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

RA54B_HUMAN
NC score	0.833455 (rank : 11)	θ value	1.09232e-21 (rank : 24)
Query Neighborhood Hits	157	Target Neighborhood Hits	54	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

CHD8_HUMAN
NC score	0.823422 (rank : 12)	θ value	4.73814e-25 (rank : 14)
Query Neighborhood Hits	157	Target Neighborhood Hits	235	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CHD6_HUMAN
NC score	0.821013 (rank : 13)	θ value	1.73987e-27 (rank : 7)
Query Neighborhood Hits	157	Target Neighborhood Hits	342	Shared Neighborhood Hits	56
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

ERCC6_HUMAN
NC score	0.819575 (rank : 14)	θ value	2.7842e-17 (rank : 25)
Query Neighborhood Hits	157	Target Neighborhood Hits	247	Shared Neighborhood Hits	42
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

CHD2_HUMAN
NC score	0.817636 (rank : 15)	θ value	1.80048e-24 (rank : 17)
Query Neighborhood Hits	157	Target Neighborhood Hits	360	Shared Neighborhood Hits	49
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

RAD54_HUMAN
NC score	0.815469 (rank : 16)	θ value	1.16975e-15 (rank : 26)
Query Neighborhood Hits	157	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

CHD9_HUMAN
NC score	0.813652 (rank : 17)	θ value	1.24688e-25 (rank : 12)
Query Neighborhood Hits	157	Target Neighborhood Hits	343	Shared Neighborhood Hits	53
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CHD1_MOUSE
NC score	0.812981 (rank : 18)	θ value	1.09232e-21 (rank : 23)
Query Neighborhood Hits	157	Target Neighborhood Hits	266	Shared Neighborhood Hits	45
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_HUMAN
NC score	0.809621 (rank : 19)	θ value	1.09232e-21 (rank : 22)
Query Neighborhood Hits	157	Target Neighborhood Hits	337	Shared Neighborhood Hits	48
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD9_MOUSE
NC score	0.809488 (rank : 20)	θ value	2.12685e-25 (rank : 13)
Query Neighborhood Hits	157	Target Neighborhood Hits	427	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

RAD54_MOUSE
NC score	0.806150 (rank : 21)	θ value	3.18553e-13 (rank : 30)
Query Neighborhood Hits	157	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

SMCA2_HUMAN
NC score	0.797506 (rank : 22)	θ value	7.80994e-28 (rank : 6)
Query Neighborhood Hits	157	Target Neighborhood Hits	503	Shared Neighborhood Hits	52
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

INOC1_MOUSE
NC score	0.792551 (rank : 23)	θ value	2.60593e-15 (rank : 27)
Query Neighborhood Hits	157	Target Neighborhood Hits	178	Shared Neighborhood Hits	39
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

INOC1_HUMAN
NC score	0.792078 (rank : 24)	θ value	4.44505e-15 (rank : 28)
Query Neighborhood Hits	157	Target Neighborhood Hits	181	Shared Neighborhood Hits	39
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

SMCA4_HUMAN
NC score	0.780899 (rank : 25)	θ value	9.54697e-26 (rank : 10)
Query Neighborhood Hits	157	Target Neighborhood Hits	597	Shared Neighborhood Hits	60
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

TTF2_HUMAN
NC score	0.771264 (rank : 26)	θ value	4.16044e-13 (rank : 31)
Query Neighborhood Hits	157	Target Neighborhood Hits	98	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

CHD3_HUMAN
NC score	0.768203 (rank : 27)	θ value	1.16704e-23 (rank : 20)
Query Neighborhood Hits	157	Target Neighborhood Hits	397	Shared Neighborhood Hits	53
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD4_HUMAN
NC score	0.767922 (rank : 28)	θ value	1.05554e-24 (rank : 15)
Query Neighborhood Hits	157	Target Neighborhood Hits	365	Shared Neighborhood Hits	53
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD5_HUMAN
NC score	0.766322 (rank : 29)	θ value	2.35151e-24 (rank : 18)
Query Neighborhood Hits	157	Target Neighborhood Hits	349	Shared Neighborhood Hits	54
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHD4_MOUSE
NC score	0.765908 (rank : 30)	θ value	1.05554e-24 (rank : 16)
Query Neighborhood Hits	157	Target Neighborhood Hits	408	Shared Neighborhood Hits	59
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

TTF2_MOUSE
NC score	0.737191 (rank : 31)	θ value	1.86753e-13 (rank : 29)
Query Neighborhood Hits	157	Target Neighborhood Hits	364	Shared Neighborhood Hits	46
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

EP400_HUMAN
NC score	0.685443 (rank : 32)	θ value	3.77169e-06 (rank : 37)
Query Neighborhood Hits	157	Target Neighborhood Hits	556	Shared Neighborhood Hits	64
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EP400_MOUSE
NC score	0.679718 (rank : 33)	θ value	4.45536e-07 (rank : 36)
Query Neighborhood Hits	157	Target Neighborhood Hits	592	Shared Neighborhood Hits	61
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

SMRA3_HUMAN
NC score	0.662872 (rank : 34)	θ value	1.74796e-11 (rank : 32)
Query Neighborhood Hits	157	Target Neighborhood Hits	265	Shared Neighborhood Hits	37
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

SMRA3_MOUSE
NC score	0.661131 (rank : 35)	θ value	9.59137e-10 (rank : 33)
Query Neighborhood Hits	157	Target Neighborhood Hits	267	Shared Neighborhood Hits	39
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

ATRX_MOUSE
NC score	0.611757 (rank : 36)	θ value	6.21693e-09 (rank : 35)
Query Neighborhood Hits	157	Target Neighborhood Hits	682	Shared Neighborhood Hits	47
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

ATRX_HUMAN
NC score	0.596884 (rank : 37)	θ value	4.76016e-09 (rank : 34)
Query Neighborhood Hits	157	Target Neighborhood Hits	842	Shared Neighborhood Hits	58
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

DDX41_MOUSE
NC score	0.118176 (rank : 38)	θ value	0.000270298 (rank : 39)
Query Neighborhood Hits	157	Target Neighborhood Hits	115	Shared Neighborhood Hits	34
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX41_HUMAN
NC score	0.115144 (rank : 39)	θ value	0.000270298 (rank : 38)
Query Neighborhood Hits	157	Target Neighborhood Hits	111	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

PL10_MOUSE
NC score	0.110290 (rank : 40)	θ value	0.21417 (rank : 59)
Query Neighborhood Hits	157	Target Neighborhood Hits	120	Shared Neighborhood Hits	34
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3X_MOUSE
NC score	0.106961 (rank : 41)	θ value	0.21417 (rank : 54)
Query Neighborhood Hits	157	Target Neighborhood Hits	117	Shared Neighborhood Hits	34
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX3X_HUMAN
NC score	0.106724 (rank : 42)	θ value	0.21417 (rank : 53)
Query Neighborhood Hits	157	Target Neighborhood Hits	122	Shared Neighborhood Hits	34
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX3Y_HUMAN
NC score	0.100917 (rank : 43)	θ value	1.81305 (rank : 80)
Query Neighborhood Hits	157	Target Neighborhood Hits	121	Shared Neighborhood Hits	34
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

BPTF_HUMAN
NC score	0.096569 (rank : 44)	θ value	0.47712 (rank : 67)
Query Neighborhood Hits	157	Target Neighborhood Hits	786	Shared Neighborhood Hits	36
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

DDX23_HUMAN
NC score	0.096145 (rank : 45)	θ value	0.0736092 (rank : 42)
Query Neighborhood Hits	157	Target Neighborhood Hits	486	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX3Y_MOUSE
NC score	0.094850 (rank : 46)	θ value	0.21417 (rank : 55)
Query Neighborhood Hits	157	Target Neighborhood Hits	126	Shared Neighborhood Hits	29
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX28_HUMAN
NC score	0.092335 (rank : 47)	θ value	0.21417 (rank : 52)
Query Neighborhood Hits	157	Target Neighborhood Hits	103	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX28_MOUSE
NC score	0.089379 (rank : 48)	θ value	0.365318 (rank : 63)
Query Neighborhood Hits	157	Target Neighborhood Hits	112	Shared Neighborhood Hits	32
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

AIRE_MOUSE
NC score	0.088529 (rank : 49)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	157	Target Neighborhood Hits	196	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

AIRE_HUMAN
NC score	0.087058 (rank : 50)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	157	Target Neighborhood Hits	144	Shared Neighborhood Hits	12
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

PHF12_HUMAN
NC score	0.082361 (rank : 51)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	157	Target Neighborhood Hits	174	Shared Neighborhood Hits	14
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
NC score	0.082329 (rank : 52)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	157	Target Neighborhood Hits	172	Shared Neighborhood Hits	12
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PF21B_MOUSE
NC score	0.082155 (rank : 53)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	157	Target Neighborhood Hits	278	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

TGON2_HUMAN
NC score	0.082035 (rank : 54)	θ value	0.21417 (rank : 60)
Query Neighborhood Hits	157	Target Neighborhood Hits	1037	Shared Neighborhood Hits	53
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

PF21B_HUMAN
NC score	0.077235 (rank : 55)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	157	Target Neighborhood Hits	197	Shared Neighborhood Hits	12
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PKCB1_HUMAN
NC score	0.077225 (rank : 56)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	157	Target Neighborhood Hits	488	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

PF21A_HUMAN
NC score	0.076334 (rank : 57)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	157	Target Neighborhood Hits	303	Shared Neighborhood Hits	16
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
NC score	0.075750 (rank : 58)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	157	Target Neighborhood Hits	285	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

DDX17_MOUSE
NC score	0.073229 (rank : 59)	θ value	0.163984 (rank : 49)
Query Neighborhood Hits	157	Target Neighborhood Hits	105	Shared Neighborhood Hits	19
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX17_HUMAN
NC score	0.073219 (rank : 60)	θ value	0.163984 (rank : 48)
Query Neighborhood Hits	157	Target Neighborhood Hits	104	Shared Neighborhood Hits	19
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

ZMY11_HUMAN
NC score	0.071151 (rank : 61)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	157	Target Neighborhood Hits	201	Shared Neighborhood Hits	12
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

DDX4_MOUSE
NC score	0.070425 (rank : 62)	θ value	2.36792 (rank : 85)
Query Neighborhood Hits	157	Target Neighborhood Hits	100	Shared Neighborhood Hits	23
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX4_HUMAN
NC score	0.070005 (rank : 63)	θ value	1.81305 (rank : 81)
Query Neighborhood Hits	157	Target Neighborhood Hits	123	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX5_HUMAN
NC score	0.069700 (rank : 64)	θ value	1.38821 (rank : 75)
Query Neighborhood Hits	157	Target Neighborhood Hits	102	Shared Neighborhood Hits	19
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
NC score	0.069647 (rank : 65)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	157	Target Neighborhood Hits	101	Shared Neighborhood Hits	19
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

ZMY11_MOUSE
NC score	0.069391 (rank : 66)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	157	Target Neighborhood Hits	198	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

BAZ1B_MOUSE
NC score	0.069132 (rank : 67)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	157	Target Neighborhood Hits	394	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

CBX5_HUMAN
NC score	0.068004 (rank : 68)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	157	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

DDX43_HUMAN
NC score	0.067697 (rank : 69)	θ value	0.0736092 (rank : 43)
Query Neighborhood Hits	157	Target Neighborhood Hits	120	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

RSF1_HUMAN
NC score	0.067520 (rank : 70)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	157	Target Neighborhood Hits	539	Shared Neighborhood Hits	24
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SP110_HUMAN
NC score	0.066201 (rank : 71)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	157	Target Neighborhood Hits	141	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

IWS1_MOUSE
NC score	0.065984 (rank : 72)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	157	Target Neighborhood Hits	1258	Shared Neighborhood Hits	46
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MLL2_HUMAN
NC score	0.064034 (rank : 73)	θ value	0.47712 (rank : 68)
Query Neighborhood Hits	157	Target Neighborhood Hits	1788	Shared Neighborhood Hits	53
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

TRI66_HUMAN
NC score	0.063606 (rank : 74)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	157	Target Neighborhood Hits	479	Shared Neighborhood Hits	32
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

BAZ1A_HUMAN
NC score	0.063179 (rank : 75)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	157	Target Neighborhood Hits	693	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

TIF1A_MOUSE
NC score	0.062628 (rank : 76)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	157	Target Neighborhood Hits	307	Shared Neighborhood Hits	17
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TRI66_MOUSE
NC score	0.061611 (rank : 77)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	157	Target Neighborhood Hits	491	Shared Neighborhood Hits	27
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TIF1G_MOUSE
NC score	0.061375 (rank : 78)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	157	Target Neighborhood Hits	498	Shared Neighborhood Hits	21
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

BAZ1B_HUMAN
NC score	0.061316 (rank : 79)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	157	Target Neighborhood Hits	701	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

NSD1_MOUSE
NC score	0.060411 (rank : 80)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	157	Target Neighborhood Hits	472	Shared Neighborhood Hits	28
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

CBX5_MOUSE
NC score	0.060013 (rank : 81)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	157	Target Neighborhood Hits	67	Shared Neighborhood Hits	10
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

TIF1A_HUMAN
NC score	0.059418 (rank : 82)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	157	Target Neighborhood Hits	327	Shared Neighborhood Hits	15
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

LY10_HUMAN
NC score	0.059155 (rank : 83)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	157	Target Neighborhood Hits	151	Shared Neighborhood Hits	11
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

DDX49_MOUSE
NC score	0.059109 (rank : 84)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	157	Target Neighborhood Hits	119	Shared Neighborhood Hits	24
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

YETS2_MOUSE
NC score	0.058712 (rank : 85)	θ value	0.365318 (rank : 66)
Query Neighborhood Hits	157	Target Neighborhood Hits	278	Shared Neighborhood Hits	23
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

IWS1_HUMAN
NC score	0.058264 (rank : 86)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	157	Target Neighborhood Hits	1241	Shared Neighborhood Hits	44
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NSD1_HUMAN
NC score	0.058058 (rank : 87)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	157	Target Neighborhood Hits	427	Shared Neighborhood Hits	23
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NIPBL_HUMAN
NC score	0.058019 (rank : 88)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	157	Target Neighborhood Hits	1311	Shared Neighborhood Hits	43
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

MLL3_HUMAN
NC score	0.057555 (rank : 89)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	157	Target Neighborhood Hits	1644	Shared Neighborhood Hits	61
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

DDX46_HUMAN
NC score	0.056794 (rank : 90)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	157	Target Neighborhood Hits	357	Shared Neighborhood Hits	25
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX25_MOUSE
NC score	0.056611 (rank : 91)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	157	Target Neighborhood Hits	98	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX46_MOUSE
NC score	0.056530 (rank : 92)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	157	Target Neighborhood Hits	358	Shared Neighborhood Hits	25
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX53_HUMAN
NC score	0.056189 (rank : 93)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	157	Target Neighborhood Hits	124	Shared Neighborhood Hits	19
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

CBX1_HUMAN
NC score	0.056163 (rank : 94)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	157	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
NC score	0.056163 (rank : 95)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	157	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

TERF2_MOUSE
NC score	0.056012 (rank : 96)	θ value	0.0193708 (rank : 40)
Query Neighborhood Hits	157	Target Neighborhood Hits	128	Shared Neighborhood Hits	11
SwissProt Accessions	O35144	Gene names	Terf2, Trf2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

YETS2_HUMAN
NC score	0.055954 (rank : 97)	θ value	0.0563607 (rank : 41)
Query Neighborhood Hits	157	Target Neighborhood Hits	212	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

DDX48_HUMAN
NC score	0.055859 (rank : 98)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	157	Target Neighborhood Hits	102	Shared Neighborhood Hits	24
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
NC score	0.055833 (rank : 99)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	157	Target Neighborhood Hits	102	Shared Neighborhood Hits	24
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX49_HUMAN
NC score	0.055795 (rank : 100)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	157	Target Neighborhood Hits	223	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DD19A_HUMAN
NC score	0.055758 (rank : 101)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	157	Target Neighborhood Hits	107	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

LEO1_MOUSE
NC score	0.055746 (rank : 102)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	157	Target Neighborhood Hits	946	Shared Neighborhood Hits	33
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

DDX47_HUMAN
NC score	0.055686 (rank : 103)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	157	Target Neighborhood Hits	97	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DD19B_HUMAN
NC score	0.055566 (rank : 104)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	157	Target Neighborhood Hits	109	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DD19A_MOUSE
NC score	0.055529 (rank : 105)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	157	Target Neighborhood Hits	105	Shared Neighborhood Hits	28
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

TIF1G_HUMAN
NC score	0.055485 (rank : 106)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	157	Target Neighborhood Hits	410	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

DDX31_HUMAN
NC score	0.054674 (rank : 107)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	157	Target Neighborhood Hits	132	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

FANCM_HUMAN
NC score	0.054645 (rank : 108)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	157	Target Neighborhood Hits	210	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

NPBL_MOUSE
NC score	0.054528 (rank : 109)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	157	Target Neighborhood Hits	1041	Shared Neighborhood Hits	44
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

DDX20_MOUSE
NC score	0.054122 (rank : 110)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	157	Target Neighborhood Hits	177	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

MLL3_MOUSE
NC score	0.054006 (rank : 111)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	157	Target Neighborhood Hits	1399	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

TXND2_MOUSE
NC score	0.053976 (rank : 112)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	157	Target Neighborhood Hits	828	Shared Neighborhood Hits	33
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

LEO1_HUMAN
NC score	0.053956 (rank : 113)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	157	Target Neighborhood Hits	958	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

DDX47_MOUSE
NC score	0.053627 (rank : 114)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	157	Target Neighborhood Hits	97	Shared Neighborhood Hits	21
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

PB1_HUMAN
NC score	0.052981 (rank : 115)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	157	Target Neighborhood Hits	261	Shared Neighborhood Hits	10
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

BAZ2A_MOUSE
NC score	0.052749 (rank : 116)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	157	Target Neighborhood Hits	744	Shared Neighborhood Hits	36
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CBX3_MOUSE
NC score	0.051701 (rank : 117)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	157	Target Neighborhood Hits	39	Shared Neighborhood Hits	12
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

RBBP6_HUMAN
NC score	0.051365 (rank : 118)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	157	Target Neighborhood Hits	1135	Shared Neighborhood Hits	37
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

DDX27_HUMAN
NC score	0.051353 (rank : 119)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	157	Target Neighborhood Hits	197	Shared Neighborhood Hits	23
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX20_HUMAN
NC score	0.051042 (rank : 120)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	157	Target Neighborhood Hits	121	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

BAZ2B_HUMAN
NC score	0.050910 (rank : 121)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	157	Target Neighborhood Hits	803	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

DDX21_MOUSE
NC score	0.050868 (rank : 122)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	157	Target Neighborhood Hits	350	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

CBX7_MOUSE
NC score	0.050843 (rank : 123)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	157	Target Neighborhood Hits	38	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VDS3	Gene names	Cbx7, D15Ertd417e
Domain Architecture
Description	Chromobox protein homolog 7.

PCLO_MOUSE
NC score	0.050767 (rank : 124)	θ value	0.47712 (rank : 69)
Query Neighborhood Hits	157	Target Neighborhood Hits	2275	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

DDX27_MOUSE
NC score	0.050745 (rank : 125)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	157	Target Neighborhood Hits	174	Shared Neighborhood Hits	22
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX52_HUMAN
NC score	0.050744 (rank : 126)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	157	Target Neighborhood Hits	107	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DPF1_HUMAN
NC score	0.050719 (rank : 127)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	157	Target Neighborhood Hits	136	Shared Neighborhood Hits	7
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

MLL4_HUMAN
NC score	0.050195 (rank : 128)	θ value	0.21417 (rank : 58)
Query Neighborhood Hits	157	Target Neighborhood Hits	722	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

IF4A2_HUMAN
NC score	0.050076 (rank : 129)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	157	Target Neighborhood Hits	102	Shared Neighborhood Hits	21
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
NC score	0.050076 (rank : 130)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	157	Target Neighborhood Hits	102	Shared Neighborhood Hits	21
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

UHRF2_HUMAN
NC score	0.050053 (rank : 131)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	157	Target Neighborhood Hits	269	Shared Neighborhood Hits	11
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

SPHK2_MOUSE
NC score	0.044319 (rank : 132)	θ value	0.0961366 (rank : 45)
Query Neighborhood Hits	157	Target Neighborhood Hits	78	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIA7, Q91VA9, Q9DBH6	Gene names	Sphk2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

AFF4_HUMAN
NC score	0.042007 (rank : 133)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	157	Target Neighborhood Hits	611	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

PCLO_HUMAN
NC score	0.038458 (rank : 134)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	157	Target Neighborhood Hits	2046	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

UBN1_HUMAN
NC score	0.037640 (rank : 135)	θ value	0.813845 (rank : 73)
Query Neighborhood Hits	157	Target Neighborhood Hits	170	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NPG3, Q13079, Q9P1P7	Gene names	UBN1
Domain Architecture	No domain graphic available
Description	Ubinuclein (Ubiquitously expressed nuclear protein) (VT4).

SPHK2_HUMAN
NC score	0.036923 (rank : 136)	θ value	1.06291 (rank : 74)
Query Neighborhood Hits	157	Target Neighborhood Hits	81	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NRA0, Q9BRN1, Q9H0Q2, Q9NWU7	Gene names	SPHK2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

TXND2_HUMAN
NC score	0.036780 (rank : 137)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	157	Target Neighborhood Hits	793	Shared Neighborhood Hits	36
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

BAG3_MOUSE
NC score	0.036595 (rank : 138)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	157	Target Neighborhood Hits	513	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

CIC_HUMAN
NC score	0.036270 (rank : 139)	θ value	0.163984 (rank : 47)
Query Neighborhood Hits	157	Target Neighborhood Hits	992	Shared Neighborhood Hits	48
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SETBP_MOUSE
NC score	0.035981 (rank : 140)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	157	Target Neighborhood Hits	352	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

K1802_MOUSE
NC score	0.033915 (rank : 141)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	157	Target Neighborhood Hits	1596	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

BAG3_HUMAN
NC score	0.029946 (rank : 142)	θ value	1.81305 (rank : 79)
Query Neighborhood Hits	157	Target Neighborhood Hits	314	Shared Neighborhood Hits	28
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

DOS_HUMAN
NC score	0.028809 (rank : 143)	θ value	2.36792 (rank : 86)
Query Neighborhood Hits	157	Target Neighborhood Hits	68	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N350, O43385	Gene names	DOS, C19orf26
Domain Architecture	No domain graphic available
Description	Protein Dos.

AFF1_HUMAN
NC score	0.028679 (rank : 144)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	157	Target Neighborhood Hits	506	Shared Neighborhood Hits	27
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

ANLN_HUMAN
NC score	0.028554 (rank : 145)	θ value	0.279714 (rank : 61)
Query Neighborhood Hits	157	Target Neighborhood Hits	222	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

SETBP_HUMAN
NC score	0.028549 (rank : 146)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	157	Target Neighborhood Hits	305	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

IF16_HUMAN
NC score	0.028175 (rank : 147)	θ value	0.21417 (rank : 57)
Query Neighborhood Hits	157	Target Neighborhood Hits	182	Shared Neighborhood Hits	12
SwissProt Accessions	Q16666, Q9UH78	Gene names	IFI16, IFNGIP1
Domain Architecture
Description	Gamma-interferon-inducible protein Ifi-16 (Interferon-inducible myeloid differentiation transcriptional activator) (IFI 16).

PANX2_MOUSE
NC score	0.027392 (rank : 148)	θ value	0.62314 (rank : 71)
Query Neighborhood Hits	157	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q6IMP4	Gene names	Panx2
Domain Architecture	No domain graphic available
Description	Pannexin-2.

EP300_HUMAN
NC score	0.026038 (rank : 149)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	157	Target Neighborhood Hits	821	Shared Neighborhood Hits	47
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

GLDN_MOUSE
NC score	0.025565 (rank : 150)	θ value	0.62314 (rank : 70)
Query Neighborhood Hits	157	Target Neighborhood Hits	155	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BMF8, Q80ZC5	Gene names	Gldn, Crgl2
Domain Architecture	No domain graphic available
Description	Gliomedin (Cancer-related gene liver 2 protein) (CRG-L2).

SYN1_HUMAN
NC score	0.025438 (rank : 151)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	157	Target Neighborhood Hits	419	Shared Neighborhood Hits	25
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

GLDN_HUMAN
NC score	0.025385 (rank : 152)	θ value	0.21417 (rank : 56)
Query Neighborhood Hits	157	Target Neighborhood Hits	159	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZMI3, Q6UXZ7, Q7Z359	Gene names	GLDN, COLM
Domain Architecture	No domain graphic available
Description	Gliomedin.

SYN1_MOUSE
NC score	0.024507 (rank : 153)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	157	Target Neighborhood Hits	363	Shared Neighborhood Hits	21
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

BAT2_MOUSE
NC score	0.024359 (rank : 154)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	157	Target Neighborhood Hits	947	Shared Neighborhood Hits	53
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

RIN2_MOUSE
NC score	0.024352 (rank : 155)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	157	Target Neighborhood Hits	72	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D684, Q99K06	Gene names	Rin2
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2).

NUFP1_HUMAN
NC score	0.023950 (rank : 156)	θ value	1.81305 (rank : 82)
Query Neighborhood Hits	157	Target Neighborhood Hits	193	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UHK0, Q8WVM5, Q96SG1	Gene names	NUFIP1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

PRG4_HUMAN
NC score	0.023889 (rank : 157)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	157	Target Neighborhood Hits	764	Shared Neighborhood Hits	39
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PSD4_MOUSE
NC score	0.023608 (rank : 158)	θ value	0.163984 (rank : 51)
Query Neighborhood Hits	157	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44	Gene names	Psd4
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).

CARD6_HUMAN
NC score	0.023354 (rank : 159)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	157	Target Neighborhood Hits	145	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BX69	Gene names	CARD6
Domain Architecture
Description	Caspase recruitment domain-containing protein 6.

ARI1A_HUMAN
NC score	0.022466 (rank : 160)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	157	Target Neighborhood Hits	787	Shared Neighborhood Hits	38
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

CIC_MOUSE
NC score	0.022084 (rank : 161)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	157	Target Neighborhood Hits	742	Shared Neighborhood Hits	35
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

GA2L2_MOUSE
NC score	0.020506 (rank : 162)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	157	Target Neighborhood Hits	395	Shared Neighborhood Hits	29
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

SEN34_MOUSE
NC score	0.019590 (rank : 163)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	157	Target Neighborhood Hits	158	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BMZ5, Q58EU2, Q99LV6, Q9CYW1	Gene names	Tsen34, Leng5, Sen34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (Leukocyte receptor cluster member 5 homolog).

R3HD1_HUMAN
NC score	0.019535 (rank : 164)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	157	Target Neighborhood Hits	203	Shared Neighborhood Hits	13
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

ETV2_MOUSE
NC score	0.018830 (rank : 165)	θ value	0.163984 (rank : 50)
Query Neighborhood Hits	157	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	P41163	Gene names	Etv2, Er71, Etsrp71
Domain Architecture
Description	ETS translocation variant 2 (Ets-related protein 71).

ALMS1_HUMAN
NC score	0.017649 (rank : 166)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	157	Target Neighborhood Hits	356	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

RIN3_HUMAN
NC score	0.017622 (rank : 167)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	157	Target Neighborhood Hits	227	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

TULP4_HUMAN
NC score	0.017490 (rank : 168)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	157	Target Neighborhood Hits	426	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

NU214_HUMAN
NC score	0.016079 (rank : 169)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	157	Target Neighborhood Hits	657	Shared Neighborhood Hits	34
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

TAF6_MOUSE
NC score	0.015616 (rank : 170)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	157	Target Neighborhood Hits	110	Shared Neighborhood Hits	8
SwissProt Accessions	Q62311	Gene names	Taf6, Taf2e
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80) (p80).

GA2L1_MOUSE
NC score	0.014873 (rank : 171)	θ value	3.0926 (rank : 95)
Query Neighborhood Hits	157	Target Neighborhood Hits	114	Shared Neighborhood Hits	9
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

MEGF9_HUMAN
NC score	0.014587 (rank : 172)	θ value	0.0961366 (rank : 44)
Query Neighborhood Hits	157	Target Neighborhood Hits	557	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

GON4L_MOUSE
NC score	0.014579 (rank : 173)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	157	Target Neighborhood Hits	455	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

FYB_MOUSE
NC score	0.014576 (rank : 174)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	157	Target Neighborhood Hits	194	Shared Neighborhood Hits	13
SwissProt Accessions	O35601, Q9Z2H3	Gene names	Fyb
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

SYN2_HUMAN
NC score	0.014482 (rank : 175)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	157	Target Neighborhood Hits	213	Shared Neighborhood Hits	13
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

TAF6_HUMAN
NC score	0.014372 (rank : 176)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	157	Target Neighborhood Hits	127	Shared Neighborhood Hits	10
SwissProt Accessions	P49848	Gene names	TAF6, TAF2E, TAFII70
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80).

GASP2_MOUSE
NC score	0.014335 (rank : 177)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	157	Target Neighborhood Hits	228	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BUY8	Gene names	Gprasp2
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 2 (GASP-2).

TCRG1_MOUSE
NC score	0.014201 (rank : 178)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	157	Target Neighborhood Hits	947	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TCRG1_HUMAN
NC score	0.014040 (rank : 179)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	157	Target Neighborhood Hits	929	Shared Neighborhood Hits	26
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

CLN3_MOUSE
NC score	0.013805 (rank : 180)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	157	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q61124, P70400	Gene names	Cln3
Domain Architecture
Description	Protein CLN3 (Battenin).

MUC5B_HUMAN
NC score	0.013676 (rank : 181)	θ value	2.36792 (rank : 87)
Query Neighborhood Hits	157	Target Neighborhood Hits	1020	Shared Neighborhood Hits	40
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

IRS1_HUMAN
NC score	0.013210 (rank : 182)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	157	Target Neighborhood Hits	109	Shared Neighborhood Hits	5
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

MYT1_HUMAN
NC score	0.012929 (rank : 183)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	157	Target Neighborhood Hits	475	Shared Neighborhood Hits	11
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

TULP4_MOUSE
NC score	0.012751 (rank : 184)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	157	Target Neighborhood Hits	247	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

SGIP1_HUMAN
NC score	0.012604 (rank : 185)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	157	Target Neighborhood Hits	198	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

LIPA3_MOUSE
NC score	0.012556 (rank : 186)	θ value	0.365318 (rank : 64)
Query Neighborhood Hits	157	Target Neighborhood Hits	636	Shared Neighborhood Hits	8
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

MYT1_MOUSE
NC score	0.012493 (rank : 187)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	157	Target Neighborhood Hits	385	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

MUCDL_MOUSE
NC score	0.011766 (rank : 188)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	157	Target Neighborhood Hits	461	Shared Neighborhood Hits	26
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

DLX5_HUMAN
NC score	0.011424 (rank : 189)	θ value	0.813845 (rank : 72)
Query Neighborhood Hits	157	Target Neighborhood Hits	405	Shared Neighborhood Hits	10
SwissProt Accessions	P56178, Q9UPL1	Gene names	DLX5
Domain Architecture
Description	Homeobox protein DLX-5.

HSH2D_HUMAN
NC score	0.011251 (rank : 190)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	157	Target Neighborhood Hits	159	Shared Neighborhood Hits	5
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

CHAC1_MOUSE
NC score	0.010485 (rank : 191)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	157	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R3J5, Q9D944	Gene names	Chac1
Domain Architecture	No domain graphic available
Description	Cation transport regulator-like protein 1.

CRTAP_HUMAN
NC score	0.009875 (rank : 192)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	157	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	O75718	Gene names	CRTAP, CASP
Domain Architecture	No domain graphic available
Description	Cartilage-associated protein precursor.

WASF2_MOUSE
NC score	0.009407 (rank : 193)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	157	Target Neighborhood Hits	315	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

CRTAP_MOUSE
NC score	0.009228 (rank : 194)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	157	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CYD3, O88698	Gene names	Crtap, Casp
Domain Architecture	No domain graphic available
Description	Cartilage-associated protein precursor.

HS74L_HUMAN
NC score	0.008964 (rank : 195)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	157	Target Neighborhood Hits	141	Shared Neighborhood Hits	4
SwissProt Accessions	O95757, Q4W5M5, Q8IWA2	Gene names	HSPA4L, APG1, OSP94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

CAC1G_HUMAN
NC score	0.008894 (rank : 196)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	157	Target Neighborhood Hits	587	Shared Neighborhood Hits	32
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

DEN1A_MOUSE
NC score	0.008861 (rank : 197)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	157	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

HS74L_MOUSE
NC score	0.008477 (rank : 198)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	157	Target Neighborhood Hits	141	Shared Neighborhood Hits	5
SwissProt Accessions	P48722, P97854, Q8BQD0, Q8CC45, Q91X29	Gene names	Hspa4l, Apg1, Hsp4l, Osp94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

DLX5_MOUSE
NC score	0.008470 (rank : 199)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	157	Target Neighborhood Hits	434	Shared Neighborhood Hits	11
SwissProt Accessions	P70396, O54876, O54877, O54878, Q9JJ45	Gene names	Dlx5
Domain Architecture
Description	Homeobox protein DLX-5.

RIMB1_HUMAN
NC score	0.007991 (rank : 200)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	157	Target Neighborhood Hits	1479	Shared Neighborhood Hits	30
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

COIA1_HUMAN
NC score	0.007678 (rank : 201)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	157	Target Neighborhood Hits	447	Shared Neighborhood Hits	23
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

COAA1_MOUSE
NC score	0.006890 (rank : 202)	θ value	3.0926 (rank : 91)
Query Neighborhood Hits	157	Target Neighborhood Hits	286	Shared Neighborhood Hits	11
SwissProt Accessions	Q05306	Gene names	Col10a1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

SYP2L_HUMAN
NC score	0.006846 (rank : 203)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	157	Target Neighborhood Hits	400	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

ZBTB3_HUMAN
NC score	0.006575 (rank : 204)	θ value	0.125558 (rank : 46)
Query Neighborhood Hits	157	Target Neighborhood Hits	910	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

CO1A1_HUMAN
NC score	0.006417 (rank : 205)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	157	Target Neighborhood Hits	475	Shared Neighborhood Hits	20
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

FIBA_HUMAN
NC score	0.005794 (rank : 206)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	157	Target Neighborhood Hits	132	Shared Neighborhood Hits	3
SwissProt Accessions	P02671, Q9BX62, Q9UCH2	Gene names	FGA
Domain Architecture
Description	Fibrinogen alpha chain precursor [Contains: Fibrinopeptide A].

WNK1_MOUSE
NC score	0.005424 (rank : 207)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	157	Target Neighborhood Hits	1179	Shared Neighborhood Hits	33
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

GGA3_HUMAN
NC score	0.005341 (rank : 208)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	157	Target Neighborhood Hits	127	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NZ52, Q15017, Q6IS16, Q9UJY3	Gene names	GGA3, KIAA0154
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

2A5D_HUMAN
NC score	0.004212 (rank : 209)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	157	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	Q14738, O00494, O00696, Q15171	Gene names	PPP2R5D
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A, B subunit, B' delta isoform) (PP2A, B subunit, B56 delta isoform) (PP2A, B subunit, PR61 delta isoform) (PP2A, B subunit, R5 delta isoform).

ZN438_HUMAN
NC score	0.004153 (rank : 210)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	157	Target Neighborhood Hits	906	Shared Neighborhood Hits	21
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

DHX9_MOUSE
NC score	0.003651 (rank : 211)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	157	Target Neighborhood Hits	72	Shared Neighborhood Hits	3
SwissProt Accessions	O70133, O35931, O54703, Q5FWY1, Q6R5F7, Q9CSA2	Gene names	Dhx9, Ddx9
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9) (mHEL-5).

PRDM2_HUMAN
NC score	0.003589 (rank : 212)	θ value	2.36792 (rank : 88)
Query Neighborhood Hits	157	Target Neighborhood Hits	1135	Shared Neighborhood Hits	26
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

M3K14_HUMAN
NC score	0.003116 (rank : 213)	θ value	0.279714 (rank : 62)
Query Neighborhood Hits	157	Target Neighborhood Hits	887	Shared Neighborhood Hits	14
SwissProt Accessions	Q99558, Q8IYN1	Gene names	MAP3K14, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK) (HsNIK).

WNK4_MOUSE
NC score	0.003108 (rank : 214)	θ value	0.365318 (rank : 65)
Query Neighborhood Hits	157	Target Neighborhood Hits	961	Shared Neighborhood Hits	15
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

MMP24_MOUSE
NC score	0.003014 (rank : 215)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	157	Target Neighborhood Hits	71	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R0S2, Q9Z0J9	Gene names	Mmp24, Mmp21, Mt5mmp
Domain Architecture
Description	Matrix metalloproteinase-24 precursor (EC 3.4.24.-) (MMP-24) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP) (MMP-21).

MMP24_HUMAN
NC score	0.003004 (rank : 216)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	157	Target Neighborhood Hits	66	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5R2, Q9H440	Gene names	MMP24, MT5MMP
Domain Architecture
Description	Matrix metalloproteinase-24 precursor (EC 3.4.24.-) (MMP-24) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP).

HERC2_HUMAN
NC score	0.002805 (rank : 217)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	157	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

BAI1_HUMAN
NC score	0.001870 (rank : 218)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	157	Target Neighborhood Hits	375	Shared Neighborhood Hits	8
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

NCA11_MOUSE
NC score	0.001463 (rank : 219)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	157	Target Neighborhood Hits	661	Shared Neighborhood Hits	17
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

HLX1_MOUSE
NC score	0.001036 (rank : 220)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	157	Target Neighborhood Hits	362	Shared Neighborhood Hits	5
SwissProt Accessions	Q61670	Gene names	Hlx1, Hlx
Domain Architecture
Description	Homeobox protein HLX1.

ZN219_HUMAN
NC score	0.000887 (rank : 221)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	157	Target Neighborhood Hits	876	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

LTBP4_MOUSE
NC score	0.000842 (rank : 222)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	157	Target Neighborhood Hits	607	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

FATH_HUMAN
NC score	-0.000215 (rank : 223)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	157	Target Neighborhood Hits	570	Shared Neighborhood Hits	6
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

EPHB2_HUMAN
NC score	-0.001807 (rank : 224)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	157	Target Neighborhood Hits	983	Shared Neighborhood Hits	7
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
NC score	-0.001816 (rank : 225)	θ value	3.0926 (rank : 93)
Query Neighborhood Hits	157	Target Neighborhood Hits	982	Shared Neighborhood Hits	7
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

ACM4_MOUSE
NC score	-0.002875 (rank : 226)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	157	Target Neighborhood Hits	894	Shared Neighborhood Hits	5
SwissProt Accessions	P32211, Q64056	Gene names	Chrm4, Chrm-4
Domain Architecture
Description	Muscarinic acetylcholine receptor M4 (Mm4 mAChR).