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Network neighborhood for query Sequence : TTF2_HUMAN

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TTF2_HUMAN
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TTF2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

TTF2_MOUSE
θ value	0 (rank : 2)	NC score	0.940595 (rank : 2)
Query Neighborhood Hits	98	Target Neighborhood Hits	364	Shared Neighborhood Hits	51
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

SMRA3_HUMAN
θ value	2.24614e-67 (rank : 3)	NC score	0.809813 (rank : 25)
Query Neighborhood Hits	98	Target Neighborhood Hits	265	Shared Neighborhood Hits	37
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

SMRA3_MOUSE
θ value	4.84666e-62 (rank : 4)	NC score	0.813398 (rank : 24)
Query Neighborhood Hits	98	Target Neighborhood Hits	267	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

RA54B_HUMAN
θ value	3.85808e-43 (rank : 5)	NC score	0.874486 (rank : 4)
Query Neighborhood Hits	98	Target Neighborhood Hits	54	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

RA54B_MOUSE
θ value	3.61106e-41 (rank : 6)	NC score	0.871769 (rank : 7)
Query Neighborhood Hits	98	Target Neighborhood Hits	59	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

SMCA1_MOUSE
θ value	2.34062e-40 (rank : 7)	NC score	0.859726 (rank : 11)
Query Neighborhood Hits	98	Target Neighborhood Hits	117	Shared Neighborhood Hits	39
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

SMCA1_HUMAN
θ value	2.58786e-39 (rank : 8)	NC score	0.861380 (rank : 8)
Query Neighborhood Hits	98	Target Neighborhood Hits	105	Shared Neighborhood Hits	41
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMCA5_MOUSE
θ value	4.13158e-37 (rank : 9)	NC score	0.860705 (rank : 9)
Query Neighborhood Hits	98	Target Neighborhood Hits	80	Shared Neighborhood Hits	39
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

SMCA5_HUMAN
θ value	9.20422e-37 (rank : 10)	NC score	0.860368 (rank : 10)
Query Neighborhood Hits	98	Target Neighborhood Hits	76	Shared Neighborhood Hits	38
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

ERCC6_HUMAN
θ value	1.32909e-35 (rank : 11)	NC score	0.859580 (rank : 12)
Query Neighborhood Hits	98	Target Neighborhood Hits	247	Shared Neighborhood Hits	45
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

SMRCD_HUMAN
θ value	3.86705e-35 (rank : 12)	NC score	0.874938 (rank : 3)
Query Neighborhood Hits	98	Target Neighborhood Hits	117	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

BTAF1_HUMAN
θ value	1.12514e-34 (rank : 13)	NC score	0.873290 (rank : 5)
Query Neighborhood Hits	98	Target Neighborhood Hits	97	Shared Neighborhood Hits	37
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

CHD8_HUMAN
θ value	5.22648e-32 (rank : 14)	NC score	0.831350 (rank : 15)
Query Neighborhood Hits	98	Target Neighborhood Hits	235	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

SMRCD_MOUSE
θ value	3.3877e-31 (rank : 15)	NC score	0.872378 (rank : 6)
Query Neighborhood Hits	98	Target Neighborhood Hits	96	Shared Neighborhood Hits	38
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

CHD2_HUMAN
θ value	2.86786e-30 (rank : 16)	NC score	0.829498 (rank : 16)
Query Neighborhood Hits	98	Target Neighborhood Hits	360	Shared Neighborhood Hits	44
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CHD6_HUMAN
θ value	3.74554e-30 (rank : 17)	NC score	0.824725 (rank : 20)
Query Neighborhood Hits	98	Target Neighborhood Hits	342	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CHD9_MOUSE
θ value	3.74554e-30 (rank : 18)	NC score	0.814292 (rank : 23)
Query Neighborhood Hits	98	Target Neighborhood Hits	427	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

CHD9_HUMAN
θ value	6.38894e-30 (rank : 19)	NC score	0.818897 (rank : 22)
Query Neighborhood Hits	98	Target Neighborhood Hits	343	Shared Neighborhood Hits	46
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CHD1_HUMAN
θ value	2.42779e-29 (rank : 20)	NC score	0.824640 (rank : 21)
Query Neighborhood Hits	98	Target Neighborhood Hits	337	Shared Neighborhood Hits	44
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_MOUSE
θ value	2.42779e-29 (rank : 21)	NC score	0.827532 (rank : 19)
Query Neighborhood Hits	98	Target Neighborhood Hits	266	Shared Neighborhood Hits	41
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

SMCA2_HUMAN
θ value	4.14116e-29 (rank : 22)	NC score	0.805813 (rank : 26)
Query Neighborhood Hits	98	Target Neighborhood Hits	503	Shared Neighborhood Hits	47
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SMCA4_HUMAN
θ value	6.61148e-27 (rank : 23)	NC score	0.792921 (rank : 27)
Query Neighborhood Hits	98	Target Neighborhood Hits	597	Shared Neighborhood Hits	50
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

RAD54_HUMAN
θ value	8.93572e-24 (rank : 24)	NC score	0.858056 (rank : 13)
Query Neighborhood Hits	98	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

INOC1_HUMAN
θ value	1.5242e-23 (rank : 25)	NC score	0.828505 (rank : 17)
Query Neighborhood Hits	98	Target Neighborhood Hits	181	Shared Neighborhood Hits	40
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

INOC1_MOUSE
θ value	3.39556e-23 (rank : 26)	NC score	0.827995 (rank : 18)
Query Neighborhood Hits	98	Target Neighborhood Hits	178	Shared Neighborhood Hits	39
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

RAD54_MOUSE
θ value	8.36355e-22 (rank : 27)	NC score	0.854351 (rank : 14)
Query Neighborhood Hits	98	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

CHD4_HUMAN
θ value	3.28887e-18 (rank : 28)	NC score	0.746341 (rank : 30)
Query Neighborhood Hits	98	Target Neighborhood Hits	365	Shared Neighborhood Hits	41
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	3.28887e-18 (rank : 29)	NC score	0.743306 (rank : 33)
Query Neighborhood Hits	98	Target Neighborhood Hits	408	Shared Neighborhood Hits	42
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD5_HUMAN
θ value	5.60996e-18 (rank : 30)	NC score	0.744549 (rank : 32)
Query Neighborhood Hits	98	Target Neighborhood Hits	349	Shared Neighborhood Hits	43
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHD3_HUMAN
θ value	8.10077e-17 (rank : 31)	NC score	0.745229 (rank : 31)
Query Neighborhood Hits	98	Target Neighborhood Hits	397	Shared Neighborhood Hits	43
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

ATRX_MOUSE
θ value	5.25075e-16 (rank : 32)	NC score	0.661297 (rank : 36)
Query Neighborhood Hits	98	Target Neighborhood Hits	682	Shared Neighborhood Hits	51
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

EP400_MOUSE
θ value	1.16975e-15 (rank : 33)	NC score	0.722482 (rank : 35)
Query Neighborhood Hits	98	Target Neighborhood Hits	592	Shared Neighborhood Hits	44
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

ATRX_HUMAN
θ value	2.60593e-15 (rank : 34)	NC score	0.641503 (rank : 37)
Query Neighborhood Hits	98	Target Neighborhood Hits	842	Shared Neighborhood Hits	55
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

EP400_HUMAN
θ value	1.68911e-14 (rank : 35)	NC score	0.728147 (rank : 34)
Query Neighborhood Hits	98	Target Neighborhood Hits	556	Shared Neighborhood Hits	43
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

SMAL1_HUMAN
θ value	1.42992e-13 (rank : 36)	NC score	0.765400 (rank : 29)
Query Neighborhood Hits	98	Target Neighborhood Hits	174	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

SMAL1_MOUSE
θ value	4.16044e-13 (rank : 37)	NC score	0.771264 (rank : 28)
Query Neighborhood Hits	98	Target Neighborhood Hits	157	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

NEIL3_HUMAN
θ value	0.00298849 (rank : 38)	NC score	0.105243 (rank : 38)
Query Neighborhood Hits	98	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TAT5, Q2PPJ3, Q8NG51, Q9NV95	Gene names	NEIL3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

NALP5_MOUSE
θ value	0.00869519 (rank : 39)	NC score	0.038094 (rank : 72)
Query Neighborhood Hits	98	Target Neighborhood Hits	560	Shared Neighborhood Hits	18
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

NEIL3_MOUSE
θ value	0.00869519 (rank : 40)	NC score	0.098608 (rank : 39)
Query Neighborhood Hits	98	Target Neighborhood Hits	39	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K203, Q8CD85, Q8R3P4	Gene names	Neil3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

FLIP1_MOUSE
θ value	0.0330416 (rank : 41)	NC score	0.020120 (rank : 89)
Query Neighborhood Hits	98	Target Neighborhood Hits	1176	Shared Neighborhood Hits	27
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

ZN451_HUMAN
θ value	0.0330416 (rank : 42)	NC score	0.019859 (rank : 90)
Query Neighborhood Hits	98	Target Neighborhood Hits	627	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4E5, Q5VVF1, Q8N380, Q8TD15, Q9NQM1	Gene names	ZNF451, COASTER, KIAA0576
Domain Architecture	No domain graphic available
Description	Zinc finger protein 451 (Coactivator for steroid receptors).

RRBP1_MOUSE
θ value	0.0563607 (rank : 43)	NC score	0.033387 (rank : 78)
Query Neighborhood Hits	98	Target Neighborhood Hits	1650	Shared Neighborhood Hits	32
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

NPDC1_MOUSE
θ value	0.0736092 (rank : 44)	NC score	0.044240 (rank : 71)
Query Neighborhood Hits	98	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q64322	Gene names	Npdc1, Npdc-1
Domain Architecture
Description	Neural proliferation differentiation and control protein 1 precursor (NPDC-1 protein).

RABE1_MOUSE
θ value	0.0736092 (rank : 45)	NC score	0.028496 (rank : 81)
Query Neighborhood Hits	98	Target Neighborhood Hits	1105	Shared Neighborhood Hits	26
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

CNGB3_MOUSE
θ value	0.0961366 (rank : 46)	NC score	0.017910 (rank : 94)
Query Neighborhood Hits	98	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

SNRK_MOUSE
θ value	0.21417 (rank : 47)	NC score	0.000017 (rank : 124)
Query Neighborhood Hits	98	Target Neighborhood Hits	849	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VDU5, Q91WX6	Gene names	Snrk
Domain Architecture	No domain graphic available
Description	SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1- related kinase).

GCC2_MOUSE
θ value	0.279714 (rank : 48)	NC score	0.014908 (rank : 100)
Query Neighborhood Hits	98	Target Neighborhood Hits	1619	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

NFAT5_MOUSE
θ value	0.365318 (rank : 49)	NC score	0.018519 (rank : 93)
Query Neighborhood Hits	98	Target Neighborhood Hits	162	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

SNRK_HUMAN
θ value	0.47712 (rank : 50)	NC score	-0.000377 (rank : 125)
Query Neighborhood Hits	98	Target Neighborhood Hits	855	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NRH2, Q14706, Q68D15, Q6IQ46, Q9NXI7	Gene names	SNRK, KIAA0096, SNFRK
Domain Architecture	No domain graphic available
Description	SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1- related kinase).

TRI29_HUMAN
θ value	0.47712 (rank : 51)	NC score	0.020261 (rank : 88)
Query Neighborhood Hits	98	Target Neighborhood Hits	273	Shared Neighborhood Hits	12
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

IWS1_MOUSE
θ value	0.62314 (rank : 52)	NC score	0.067162 (rank : 41)
Query Neighborhood Hits	98	Target Neighborhood Hits	1258	Shared Neighborhood Hits	30
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JIP3_HUMAN
θ value	0.62314 (rank : 53)	NC score	0.019487 (rank : 91)
Query Neighborhood Hits	98	Target Neighborhood Hits	1039	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

ZN451_MOUSE
θ value	0.62314 (rank : 54)	NC score	0.015454 (rank : 99)
Query Neighborhood Hits	98	Target Neighborhood Hits	643	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C0P7	Gene names	Znf451, Zfp451
Domain Architecture	No domain graphic available
Description	Zinc finger protein 451.

WDHD1_MOUSE
θ value	0.813845 (rank : 55)	NC score	0.012439 (rank : 106)
Query Neighborhood Hits	98	Target Neighborhood Hits	414	Shared Neighborhood Hits	4
SwissProt Accessions	P59328, Q6P408	Gene names	Wdhd1, And1
Domain Architecture	No domain graphic available
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

DHX34_MOUSE
θ value	1.06291 (rank : 56)	NC score	0.008578 (rank : 115)
Query Neighborhood Hits	98	Target Neighborhood Hits	235	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DBV3	Gene names	Dhx34, Ddx34, Kiaa0134
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

EZRI_HUMAN
θ value	1.06291 (rank : 57)	NC score	0.009924 (rank : 114)
Query Neighborhood Hits	98	Target Neighborhood Hits	663	Shared Neighborhood Hits	17
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

NKTR_MOUSE
θ value	1.06291 (rank : 58)	NC score	0.030030 (rank : 80)
Query Neighborhood Hits	98	Target Neighborhood Hits	417	Shared Neighborhood Hits	18
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

TOP3A_HUMAN
θ value	1.38821 (rank : 59)	NC score	0.037408 (rank : 74)
Query Neighborhood Hits	98	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q13472, Q13473	Gene names	TOP3A, TOP3
Domain Architecture
Description	DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha).

ANR11_HUMAN
θ value	1.81305 (rank : 60)	NC score	0.023045 (rank : 85)
Query Neighborhood Hits	98	Target Neighborhood Hits	1289	Shared Neighborhood Hits	32
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

MGAT5_HUMAN
θ value	1.81305 (rank : 61)	NC score	0.026461 (rank : 83)
Query Neighborhood Hits	98	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q09328	Gene names	MGAT5, GGNT5
Domain Architecture	No domain graphic available
Description	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase V (EC 2.4.1.155) (Mannoside acetylglucosaminyltransferase 5) (Alpha- mannoside beta-1,6-N-acetylglucosaminyltransferase) (N- acetylglucosaminyl-transferase V) (GNT-V) (GlcNAc-T V).

MGAT5_MOUSE
θ value	1.81305 (rank : 62)	NC score	0.026441 (rank : 84)
Query Neighborhood Hits	98	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R4G6	Gene names	Mgat5
Domain Architecture	No domain graphic available
Description	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase V (EC 2.4.1.155) (Mannoside acetylglucosaminyltransferase 5) (Alpha- mannoside beta-1,6-N-acetylglucosaminyltransferase) (N- acetylglucosaminyl-transferase V) (GNT-V) (GlcNAc-T V).

TCEA1_HUMAN
θ value	1.81305 (rank : 63)	NC score	0.011946 (rank : 108)
Query Neighborhood Hits	98	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	P23193, Q15563, Q6FG87	Gene names	TCEA1, TFIIS
Domain Architecture
Description	Transcription elongation factor A protein 1 (Transcription elongation factor S-II protein 1) (Transcription elongation factor TFIIS.o).

CCHCR_MOUSE
θ value	2.36792 (rank : 64)	NC score	0.012611 (rank : 104)
Query Neighborhood Hits	98	Target Neighborhood Hits	932	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

DPOLA_MOUSE
θ value	2.36792 (rank : 65)	NC score	0.016168 (rank : 96)
Query Neighborhood Hits	98	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	P33609	Gene names	Pola1, Pola
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

HRX_HUMAN
θ value	2.36792 (rank : 66)	NC score	0.036423 (rank : 75)
Query Neighborhood Hits	98	Target Neighborhood Hits	825	Shared Neighborhood Hits	21
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

RABE1_HUMAN
θ value	2.36792 (rank : 67)	NC score	0.022591 (rank : 86)
Query Neighborhood Hits	98	Target Neighborhood Hits	1104	Shared Neighborhood Hits	24
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

TPR_HUMAN
θ value	2.36792 (rank : 68)	NC score	0.015796 (rank : 97)
Query Neighborhood Hits	98	Target Neighborhood Hits	1921	Shared Neighborhood Hits	35
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

ZN690_HUMAN
θ value	2.36792 (rank : 69)	NC score	-0.003547 (rank : 127)
Query Neighborhood Hits	98	Target Neighborhood Hits	777	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IWY8, Q32M75, Q32M76, Q8NA40	Gene names	ZNF690
Domain Architecture	No domain graphic available
Description	Zinc finger protein 690.

EEA1_HUMAN
θ value	3.0926 (rank : 70)	NC score	0.012337 (rank : 107)
Query Neighborhood Hits	98	Target Neighborhood Hits	1796	Shared Neighborhood Hits	33
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

PCLO_HUMAN
θ value	3.0926 (rank : 71)	NC score	0.027580 (rank : 82)
Query Neighborhood Hits	98	Target Neighborhood Hits	2046	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

ZBT40_HUMAN
θ value	3.0926 (rank : 72)	NC score	-0.000720 (rank : 126)
Query Neighborhood Hits	98	Target Neighborhood Hits	949	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.

ATF1_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.011059 (rank : 112)
Query Neighborhood Hits	98	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	P81269	Gene names	Atf1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-1 (Activating transcription factor 1) (TCR-ATF1).

EFHC2_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.019355 (rank : 92)
Query Neighborhood Hits	98	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JST6, Q5JST8, Q68DK4, Q8NEI0, Q9H653	Gene names	EFHC2
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member C2.

GP179_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.020940 (rank : 87)
Query Neighborhood Hits	98	Target Neighborhood Hits	372	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

PKHA6_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.013824 (rank : 101)
Query Neighborhood Hits	98	Target Neighborhood Hits	591	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

SIA7A_MOUSE
θ value	4.03905 (rank : 77)	NC score	0.011537 (rank : 110)
Query Neighborhood Hits	98	Target Neighborhood Hits	203	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZ39, Q9JJP5	Gene names	St6galnac1, Siat7a
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

STX12_HUMAN
θ value	4.03905 (rank : 78)	NC score	0.011832 (rank : 109)
Query Neighborhood Hits	98	Target Neighborhood Hits	226	Shared Neighborhood Hits	7
SwissProt Accessions	Q86Y82, O95564	Gene names	STX12
Domain Architecture
Description	Syntaxin-12.

UACA_HUMAN
θ value	4.03905 (rank : 79)	NC score	0.008093 (rank : 116)
Query Neighborhood Hits	98	Target Neighborhood Hits	1622	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

ZW10_HUMAN
θ value	4.03905 (rank : 80)	NC score	0.013012 (rank : 102)
Query Neighborhood Hits	98	Target Neighborhood Hits	101	Shared Neighborhood Hits	6
SwissProt Accessions	O43264	Gene names	ZW10
Domain Architecture
Description	Centromere/kinetochore protein zw10 homolog.

COIA1_MOUSE
θ value	5.27518 (rank : 81)	NC score	0.006053 (rank : 120)
Query Neighborhood Hits	98	Target Neighborhood Hits	481	Shared Neighborhood Hits	6
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

O2T33_HUMAN
θ value	5.27518 (rank : 82)	NC score	-0.004220 (rank : 128)
Query Neighborhood Hits	98	Target Neighborhood Hits	689	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NG76	Gene names	OR2T33
Domain Architecture	No domain graphic available
Description	Olfactory receptor 2T33 (Olfactory receptor OR1-56).

SYTL1_MOUSE
θ value	5.27518 (rank : 83)	NC score	0.006453 (rank : 119)
Query Neighborhood Hits	98	Target Neighborhood Hits	314	Shared Neighborhood Hits	7
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

ALMS1_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.016356 (rank : 95)
Query Neighborhood Hits	98	Target Neighborhood Hits	356	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

APEX2_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.035409 (rank : 76)
Query Neighborhood Hits	98	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UBZ4, Q9Y5X7	Gene names	APEX2, APE2, APEXL2, XTH2
Domain Architecture	No domain graphic available
Description	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 4.2.99.18) (Apurinic- apyrimidinic endonuclease 2) (AP endonuclease 2) (APEX nuclease 2) (APEX nuclease-like 2) (AP endonuclease XTH2).

APEX2_MOUSE
θ value	6.88961 (rank : 86)	NC score	0.033234 (rank : 79)
Query Neighborhood Hits	98	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	Q68G58, Q8BJP7, Q8BTR7, Q8BUZ2, Q8BYE9, Q8R018, Q8R328, Q9CS12	Gene names	Apex2, Ape2
Domain Architecture	No domain graphic available
Description	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 4.2.99.18) (Apurinic- apyrimidinic endonuclease 2) (AP endonuclease 2) (APEX nuclease 2).

CF064_MOUSE
θ value	6.88961 (rank : 87)	NC score	0.015482 (rank : 98)
Query Neighborhood Hits	98	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K190	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf64 homolog.

DEN2A_MOUSE
θ value	6.88961 (rank : 88)	NC score	0.005566 (rank : 121)
Query Neighborhood Hits	98	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C4S8, Q3TJU2, Q3TUG3, Q3UXA3	Gene names	Dennd2a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

HASP_MOUSE
θ value	6.88961 (rank : 89)	NC score	0.012699 (rank : 103)
Query Neighborhood Hits	98	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z0R0, Q99MU9, Q9JJJ4	Gene names	Gsg2
Domain Architecture
Description	Serine/threonine-protein kinase Haspin (EC 2.7.11.1) (Haploid germ cell-specific nuclear protein kinase) (Germ cell-specific gene 2 protein).

STX12_MOUSE
θ value	6.88961 (rank : 90)	NC score	0.011063 (rank : 111)
Query Neighborhood Hits	98	Target Neighborhood Hits	283	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ER00, Q3UIV9, Q921T9	Gene names	Stx12
Domain Architecture
Description	Syntaxin-12.

TOP3A_MOUSE
θ value	6.88961 (rank : 91)	NC score	0.034838 (rank : 77)
Query Neighborhood Hits	98	Target Neighborhood Hits	24	Shared Neighborhood Hits	8
SwissProt Accessions	O70157	Gene names	Top3a, Top3
Domain Architecture
Description	DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha).

YTDC1_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.037707 (rank : 73)
Query Neighborhood Hits	98	Target Neighborhood Hits	458	Shared Neighborhood Hits	17
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

DPOLA_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.012480 (rank : 105)
Query Neighborhood Hits	98	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	P09884, Q86UQ7	Gene names	POLA1, POLA
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

GOGA3_MOUSE
θ value	8.99809 (rank : 94)	NC score	0.006460 (rank : 118)
Query Neighborhood Hits	98	Target Neighborhood Hits	1437	Shared Neighborhood Hits	23
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

POT14_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.000992 (rank : 123)
Query Neighborhood Hits	98	Target Neighborhood Hits	403	Shared Neighborhood Hits	5
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

SPC25_MOUSE
θ value	8.99809 (rank : 96)	NC score	0.011005 (rank : 113)
Query Neighborhood Hits	98	Target Neighborhood Hits	241	Shared Neighborhood Hits	11
SwissProt Accessions	Q3UA16, Q9D021, Q9D1K6	Gene names	Spbc25
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc25.

TUFT1_MOUSE
θ value	8.99809 (rank : 97)	NC score	0.007282 (rank : 117)
Query Neighborhood Hits	98	Target Neighborhood Hits	732	Shared Neighborhood Hits	16
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

WWP2_HUMAN
θ value	8.99809 (rank : 98)	NC score	0.001297 (rank : 122)
Query Neighborhood Hits	98	Target Neighborhood Hits	177	Shared Neighborhood Hits	3
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

AIRE_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.064091 (rank : 45)
Query Neighborhood Hits	98	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.065254 (rank : 42)
Query Neighborhood Hits	98	Target Neighborhood Hits	196	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

BAZ1A_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.050532 (rank : 70)
Query Neighborhood Hits	98	Target Neighborhood Hits	693	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ1B_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.053769 (rank : 64)
Query Neighborhood Hits	98	Target Neighborhood Hits	394	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BPTF_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.067338 (rank : 40)
Query Neighborhood Hits	98	Target Neighborhood Hits	786	Shared Neighborhood Hits	26
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CBX1_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.052074 (rank : 66)
Query Neighborhood Hits	98	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.052074 (rank : 67)
Query Neighborhood Hits	98	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

CBX5_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.060603 (rank : 49)
Query Neighborhood Hits	98	Target Neighborhood Hits	70	Shared Neighborhood Hits	10
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CBX5_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.053284 (rank : 65)
Query Neighborhood Hits	98	Target Neighborhood Hits	67	Shared Neighborhood Hits	9
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

IWS1_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.060704 (rank : 48)
Query Neighborhood Hits	98	Target Neighborhood Hits	1241	Shared Neighborhood Hits	28
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LEO1_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.054027 (rank : 63)
Query Neighborhood Hits	98	Target Neighborhood Hits	958	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LEO1_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.056579 (rank : 56)
Query Neighborhood Hits	98	Target Neighborhood Hits	946	Shared Neighborhood Hits	29
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

NIPBL_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.058788 (rank : 51)
Query Neighborhood Hits	98	Target Neighborhood Hits	1311	Shared Neighborhood Hits	32
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.059083 (rank : 50)
Query Neighborhood Hits	98	Target Neighborhood Hits	1041	Shared Neighborhood Hits	29
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PF21A_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.054349 (rank : 61)
Query Neighborhood Hits	98	Target Neighborhood Hits	303	Shared Neighborhood Hits	12
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.055267 (rank : 59)
Query Neighborhood Hits	98	Target Neighborhood Hits	285	Shared Neighborhood Hits	13
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21B_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.054103 (rank : 62)
Query Neighborhood Hits	98	Target Neighborhood Hits	197	Shared Neighborhood Hits	7
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_MOUSE
θ value	θ > 10 (rank : 116)	NC score	0.056257 (rank : 58)
Query Neighborhood Hits	98	Target Neighborhood Hits	278	Shared Neighborhood Hits	10
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF12_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.061535 (rank : 47)
Query Neighborhood Hits	98	Target Neighborhood Hits	174	Shared Neighborhood Hits	7
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.061902 (rank : 46)
Query Neighborhood Hits	98	Target Neighborhood Hits	172	Shared Neighborhood Hits	8
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PKCB1_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.064821 (rank : 43)
Query Neighborhood Hits	98	Target Neighborhood Hits	488	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

RBBP6_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.057361 (rank : 53)
Query Neighborhood Hits	98	Target Neighborhood Hits	1135	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.058261 (rank : 52)
Query Neighborhood Hits	98	Target Neighborhood Hits	1014	Shared Neighborhood Hits	30
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RSF1_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.056662 (rank : 55)
Query Neighborhood Hits	98	Target Neighborhood Hits	539	Shared Neighborhood Hits	23
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SFR11_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.051178 (rank : 69)
Query Neighborhood Hits	98	Target Neighborhood Hits	246	Shared Neighborhood Hits	12
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

SP110_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.051319 (rank : 68)
Query Neighborhood Hits	98	Target Neighborhood Hits	141	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

TGON2_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.064414 (rank : 44)
Query Neighborhood Hits	98	Target Neighborhood Hits	1037	Shared Neighborhood Hits	28
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TXND2_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.056912 (rank : 54)
Query Neighborhood Hits	98	Target Neighborhood Hits	828	Shared Neighborhood Hits	26
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

ZMY11_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.056487 (rank : 57)
Query Neighborhood Hits	98	Target Neighborhood Hits	201	Shared Neighborhood Hits	10
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

ZMY11_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.054504 (rank : 60)
Query Neighborhood Hits	98	Target Neighborhood Hits	198	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

Hits sorted by NC score

TTF2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

TTF2_MOUSE
NC score	0.940595 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	98	Target Neighborhood Hits	364	Shared Neighborhood Hits	51
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

SMRCD_HUMAN
NC score	0.874938 (rank : 3)	θ value	3.86705e-35 (rank : 12)
Query Neighborhood Hits	98	Target Neighborhood Hits	117	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

RA54B_HUMAN
NC score	0.874486 (rank : 4)	θ value	3.85808e-43 (rank : 5)
Query Neighborhood Hits	98	Target Neighborhood Hits	54	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

BTAF1_HUMAN
NC score	0.873290 (rank : 5)	θ value	1.12514e-34 (rank : 13)
Query Neighborhood Hits	98	Target Neighborhood Hits	97	Shared Neighborhood Hits	37
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

SMRCD_MOUSE
NC score	0.872378 (rank : 6)	θ value	3.3877e-31 (rank : 15)
Query Neighborhood Hits	98	Target Neighborhood Hits	96	Shared Neighborhood Hits	38
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

RA54B_MOUSE
NC score	0.871769 (rank : 7)	θ value	3.61106e-41 (rank : 6)
Query Neighborhood Hits	98	Target Neighborhood Hits	59	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

SMCA1_HUMAN
NC score	0.861380 (rank : 8)	θ value	2.58786e-39 (rank : 8)
Query Neighborhood Hits	98	Target Neighborhood Hits	105	Shared Neighborhood Hits	41
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMCA5_MOUSE
NC score	0.860705 (rank : 9)	θ value	4.13158e-37 (rank : 9)
Query Neighborhood Hits	98	Target Neighborhood Hits	80	Shared Neighborhood Hits	39
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

SMCA5_HUMAN
NC score	0.860368 (rank : 10)	θ value	9.20422e-37 (rank : 10)
Query Neighborhood Hits	98	Target Neighborhood Hits	76	Shared Neighborhood Hits	38
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

SMCA1_MOUSE
NC score	0.859726 (rank : 11)	θ value	2.34062e-40 (rank : 7)
Query Neighborhood Hits	98	Target Neighborhood Hits	117	Shared Neighborhood Hits	39
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

ERCC6_HUMAN
NC score	0.859580 (rank : 12)	θ value	1.32909e-35 (rank : 11)
Query Neighborhood Hits	98	Target Neighborhood Hits	247	Shared Neighborhood Hits	45
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

RAD54_HUMAN
NC score	0.858056 (rank : 13)	θ value	8.93572e-24 (rank : 24)
Query Neighborhood Hits	98	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

RAD54_MOUSE
NC score	0.854351 (rank : 14)	θ value	8.36355e-22 (rank : 27)
Query Neighborhood Hits	98	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

CHD8_HUMAN
NC score	0.831350 (rank : 15)	θ value	5.22648e-32 (rank : 14)
Query Neighborhood Hits	98	Target Neighborhood Hits	235	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CHD2_HUMAN
NC score	0.829498 (rank : 16)	θ value	2.86786e-30 (rank : 16)
Query Neighborhood Hits	98	Target Neighborhood Hits	360	Shared Neighborhood Hits	44
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

INOC1_HUMAN
NC score	0.828505 (rank : 17)	θ value	1.5242e-23 (rank : 25)
Query Neighborhood Hits	98	Target Neighborhood Hits	181	Shared Neighborhood Hits	40
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

INOC1_MOUSE
NC score	0.827995 (rank : 18)	θ value	3.39556e-23 (rank : 26)
Query Neighborhood Hits	98	Target Neighborhood Hits	178	Shared Neighborhood Hits	39
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

CHD1_MOUSE
NC score	0.827532 (rank : 19)	θ value	2.42779e-29 (rank : 21)
Query Neighborhood Hits	98	Target Neighborhood Hits	266	Shared Neighborhood Hits	41
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD6_HUMAN
NC score	0.824725 (rank : 20)	θ value	3.74554e-30 (rank : 17)
Query Neighborhood Hits	98	Target Neighborhood Hits	342	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CHD1_HUMAN
NC score	0.824640 (rank : 21)	θ value	2.42779e-29 (rank : 20)
Query Neighborhood Hits	98	Target Neighborhood Hits	337	Shared Neighborhood Hits	44
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD9_HUMAN
NC score	0.818897 (rank : 22)	θ value	6.38894e-30 (rank : 19)
Query Neighborhood Hits	98	Target Neighborhood Hits	343	Shared Neighborhood Hits	46
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CHD9_MOUSE
NC score	0.814292 (rank : 23)	θ value	3.74554e-30 (rank : 18)
Query Neighborhood Hits	98	Target Neighborhood Hits	427	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

SMRA3_MOUSE
NC score	0.813398 (rank : 24)	θ value	4.84666e-62 (rank : 4)
Query Neighborhood Hits	98	Target Neighborhood Hits	267	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

SMRA3_HUMAN
NC score	0.809813 (rank : 25)	θ value	2.24614e-67 (rank : 3)
Query Neighborhood Hits	98	Target Neighborhood Hits	265	Shared Neighborhood Hits	37
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

SMCA2_HUMAN
NC score	0.805813 (rank : 26)	θ value	4.14116e-29 (rank : 22)
Query Neighborhood Hits	98	Target Neighborhood Hits	503	Shared Neighborhood Hits	47
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SMCA4_HUMAN
NC score	0.792921 (rank : 27)	θ value	6.61148e-27 (rank : 23)
Query Neighborhood Hits	98	Target Neighborhood Hits	597	Shared Neighborhood Hits	50
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SMAL1_MOUSE
NC score	0.771264 (rank : 28)	θ value	4.16044e-13 (rank : 37)
Query Neighborhood Hits	98	Target Neighborhood Hits	157	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

SMAL1_HUMAN
NC score	0.765400 (rank : 29)	θ value	1.42992e-13 (rank : 36)
Query Neighborhood Hits	98	Target Neighborhood Hits	174	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

CHD4_HUMAN
NC score	0.746341 (rank : 30)	θ value	3.28887e-18 (rank : 28)
Query Neighborhood Hits	98	Target Neighborhood Hits	365	Shared Neighborhood Hits	41
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD3_HUMAN
NC score	0.745229 (rank : 31)	θ value	8.10077e-17 (rank : 31)
Query Neighborhood Hits	98	Target Neighborhood Hits	397	Shared Neighborhood Hits	43
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD5_HUMAN
NC score	0.744549 (rank : 32)	θ value	5.60996e-18 (rank : 30)
Query Neighborhood Hits	98	Target Neighborhood Hits	349	Shared Neighborhood Hits	43
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHD4_MOUSE
NC score	0.743306 (rank : 33)	θ value	3.28887e-18 (rank : 29)
Query Neighborhood Hits	98	Target Neighborhood Hits	408	Shared Neighborhood Hits	42
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

EP400_HUMAN
NC score	0.728147 (rank : 34)	θ value	1.68911e-14 (rank : 35)
Query Neighborhood Hits	98	Target Neighborhood Hits	556	Shared Neighborhood Hits	43
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EP400_MOUSE
NC score	0.722482 (rank : 35)	θ value	1.16975e-15 (rank : 33)
Query Neighborhood Hits	98	Target Neighborhood Hits	592	Shared Neighborhood Hits	44
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

ATRX_MOUSE
NC score	0.661297 (rank : 36)	θ value	5.25075e-16 (rank : 32)
Query Neighborhood Hits	98	Target Neighborhood Hits	682	Shared Neighborhood Hits	51
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

ATRX_HUMAN
NC score	0.641503 (rank : 37)	θ value	2.60593e-15 (rank : 34)
Query Neighborhood Hits	98	Target Neighborhood Hits	842	Shared Neighborhood Hits	55
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

NEIL3_HUMAN
NC score	0.105243 (rank : 38)	θ value	0.00298849 (rank : 38)
Query Neighborhood Hits	98	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TAT5, Q2PPJ3, Q8NG51, Q9NV95	Gene names	NEIL3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

NEIL3_MOUSE
NC score	0.098608 (rank : 39)	θ value	0.00869519 (rank : 40)
Query Neighborhood Hits	98	Target Neighborhood Hits	39	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K203, Q8CD85, Q8R3P4	Gene names	Neil3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

BPTF_HUMAN
NC score	0.067338 (rank : 40)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	98	Target Neighborhood Hits	786	Shared Neighborhood Hits	26
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

IWS1_MOUSE
NC score	0.067162 (rank : 41)	θ value	0.62314 (rank : 52)
Query Neighborhood Hits	98	Target Neighborhood Hits	1258	Shared Neighborhood Hits	30
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

AIRE_MOUSE
NC score	0.065254 (rank : 42)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	98	Target Neighborhood Hits	196	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

PKCB1_HUMAN
NC score	0.064821 (rank : 43)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	98	Target Neighborhood Hits	488	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

TGON2_HUMAN
NC score	0.064414 (rank : 44)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	98	Target Neighborhood Hits	1037	Shared Neighborhood Hits	28
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

AIRE_HUMAN
NC score	0.064091 (rank : 45)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	98	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

PHF12_MOUSE
NC score	0.061902 (rank : 46)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	98	Target Neighborhood Hits	172	Shared Neighborhood Hits	8
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_HUMAN
NC score	0.061535 (rank : 47)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	98	Target Neighborhood Hits	174	Shared Neighborhood Hits	7
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

IWS1_HUMAN
NC score	0.060704 (rank : 48)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	98	Target Neighborhood Hits	1241	Shared Neighborhood Hits	28
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CBX5_HUMAN
NC score	0.060603 (rank : 49)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	98	Target Neighborhood Hits	70	Shared Neighborhood Hits	10
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

NPBL_MOUSE
NC score	0.059083 (rank : 50)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	98	Target Neighborhood Hits	1041	Shared Neighborhood Hits	29
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NIPBL_HUMAN
NC score	0.058788 (rank : 51)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	98	Target Neighborhood Hits	1311	Shared Neighborhood Hits	32
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

RBBP6_MOUSE
NC score	0.058261 (rank : 52)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	98	Target Neighborhood Hits	1014	Shared Neighborhood Hits	30
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RBBP6_HUMAN
NC score	0.057361 (rank : 53)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	98	Target Neighborhood Hits	1135	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

TXND2_MOUSE
NC score	0.056912 (rank : 54)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	98	Target Neighborhood Hits	828	Shared Neighborhood Hits	26
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

RSF1_HUMAN
NC score	0.056662 (rank : 55)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	98	Target Neighborhood Hits	539	Shared Neighborhood Hits	23
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

LEO1_MOUSE
NC score	0.056579 (rank : 56)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	98	Target Neighborhood Hits	946	Shared Neighborhood Hits	29
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

ZMY11_HUMAN
NC score	0.056487 (rank : 57)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	98	Target Neighborhood Hits	201	Shared Neighborhood Hits	10
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

PF21B_MOUSE
NC score	0.056257 (rank : 58)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	98	Target Neighborhood Hits	278	Shared Neighborhood Hits	10
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21A_MOUSE
NC score	0.055267 (rank : 59)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	98	Target Neighborhood Hits	285	Shared Neighborhood Hits	13
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

ZMY11_MOUSE
NC score	0.054504 (rank : 60)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	98	Target Neighborhood Hits	198	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

PF21A_HUMAN
NC score	0.054349 (rank : 61)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	98	Target Neighborhood Hits	303	Shared Neighborhood Hits	12
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21B_HUMAN
NC score	0.054103 (rank : 62)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	98	Target Neighborhood Hits	197	Shared Neighborhood Hits	7
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

LEO1_HUMAN
NC score	0.054027 (rank : 63)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	98	Target Neighborhood Hits	958	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

BAZ1B_MOUSE
NC score	0.053769 (rank : 64)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	98	Target Neighborhood Hits	394	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

CBX5_MOUSE
NC score	0.053284 (rank : 65)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	98	Target Neighborhood Hits	67	Shared Neighborhood Hits	9
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

CBX1_HUMAN
NC score	0.052074 (rank : 66)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	98	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
NC score	0.052074 (rank : 67)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	98	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

SP110_HUMAN
NC score	0.051319 (rank : 68)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	98	Target Neighborhood Hits	141	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

SFR11_HUMAN
NC score	0.051178 (rank : 69)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	98	Target Neighborhood Hits	246	Shared Neighborhood Hits	12
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

BAZ1A_HUMAN
NC score	0.050532 (rank : 70)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	98	Target Neighborhood Hits	693	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

NPDC1_MOUSE
NC score	0.044240 (rank : 71)	θ value	0.0736092 (rank : 44)
Query Neighborhood Hits	98	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q64322	Gene names	Npdc1, Npdc-1
Domain Architecture
Description	Neural proliferation differentiation and control protein 1 precursor (NPDC-1 protein).

NALP5_MOUSE
NC score	0.038094 (rank : 72)	θ value	0.00869519 (rank : 39)
Query Neighborhood Hits	98	Target Neighborhood Hits	560	Shared Neighborhood Hits	18
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

YTDC1_HUMAN
NC score	0.037707 (rank : 73)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	98	Target Neighborhood Hits	458	Shared Neighborhood Hits	17
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

TOP3A_HUMAN
NC score	0.037408 (rank : 74)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	98	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q13472, Q13473	Gene names	TOP3A, TOP3
Domain Architecture
Description	DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha).

HRX_HUMAN
NC score	0.036423 (rank : 75)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	98	Target Neighborhood Hits	825	Shared Neighborhood Hits	21
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

APEX2_HUMAN
NC score	0.035409 (rank : 76)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	98	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UBZ4, Q9Y5X7	Gene names	APEX2, APE2, APEXL2, XTH2
Domain Architecture	No domain graphic available
Description	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 4.2.99.18) (Apurinic- apyrimidinic endonuclease 2) (AP endonuclease 2) (APEX nuclease 2) (APEX nuclease-like 2) (AP endonuclease XTH2).

TOP3A_MOUSE
NC score	0.034838 (rank : 77)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	98	Target Neighborhood Hits	24	Shared Neighborhood Hits	8
SwissProt Accessions	O70157	Gene names	Top3a, Top3
Domain Architecture
Description	DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha).

RRBP1_MOUSE
NC score	0.033387 (rank : 78)	θ value	0.0563607 (rank : 43)
Query Neighborhood Hits	98	Target Neighborhood Hits	1650	Shared Neighborhood Hits	32
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

APEX2_MOUSE
NC score	0.033234 (rank : 79)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	98	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	Q68G58, Q8BJP7, Q8BTR7, Q8BUZ2, Q8BYE9, Q8R018, Q8R328, Q9CS12	Gene names	Apex2, Ape2
Domain Architecture	No domain graphic available
Description	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 4.2.99.18) (Apurinic- apyrimidinic endonuclease 2) (AP endonuclease 2) (APEX nuclease 2).

NKTR_MOUSE
NC score	0.030030 (rank : 80)	θ value	1.06291 (rank : 58)
Query Neighborhood Hits	98	Target Neighborhood Hits	417	Shared Neighborhood Hits	18
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

RABE1_MOUSE
NC score	0.028496 (rank : 81)	θ value	0.0736092 (rank : 45)
Query Neighborhood Hits	98	Target Neighborhood Hits	1105	Shared Neighborhood Hits	26
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

PCLO_HUMAN
NC score	0.027580 (rank : 82)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	98	Target Neighborhood Hits	2046	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

MGAT5_HUMAN
NC score	0.026461 (rank : 83)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	98	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q09328	Gene names	MGAT5, GGNT5
Domain Architecture	No domain graphic available
Description	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase V (EC 2.4.1.155) (Mannoside acetylglucosaminyltransferase 5) (Alpha- mannoside beta-1,6-N-acetylglucosaminyltransferase) (N- acetylglucosaminyl-transferase V) (GNT-V) (GlcNAc-T V).

MGAT5_MOUSE
NC score	0.026441 (rank : 84)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	98	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R4G6	Gene names	Mgat5
Domain Architecture	No domain graphic available
Description	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase V (EC 2.4.1.155) (Mannoside acetylglucosaminyltransferase 5) (Alpha- mannoside beta-1,6-N-acetylglucosaminyltransferase) (N- acetylglucosaminyl-transferase V) (GNT-V) (GlcNAc-T V).

ANR11_HUMAN
NC score	0.023045 (rank : 85)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	98	Target Neighborhood Hits	1289	Shared Neighborhood Hits	32
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

RABE1_HUMAN
NC score	0.022591 (rank : 86)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	98	Target Neighborhood Hits	1104	Shared Neighborhood Hits	24
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

GP179_HUMAN
NC score	0.020940 (rank : 87)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	98	Target Neighborhood Hits	372	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

TRI29_HUMAN
NC score	0.020261 (rank : 88)	θ value	0.47712 (rank : 51)
Query Neighborhood Hits	98	Target Neighborhood Hits	273	Shared Neighborhood Hits	12
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

FLIP1_MOUSE
NC score	0.020120 (rank : 89)	θ value	0.0330416 (rank : 41)
Query Neighborhood Hits	98	Target Neighborhood Hits	1176	Shared Neighborhood Hits	27
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

ZN451_HUMAN
NC score	0.019859 (rank : 90)	θ value	0.0330416 (rank : 42)
Query Neighborhood Hits	98	Target Neighborhood Hits	627	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4E5, Q5VVF1, Q8N380, Q8TD15, Q9NQM1	Gene names	ZNF451, COASTER, KIAA0576
Domain Architecture	No domain graphic available
Description	Zinc finger protein 451 (Coactivator for steroid receptors).

JIP3_HUMAN
NC score	0.019487 (rank : 91)	θ value	0.62314 (rank : 53)
Query Neighborhood Hits	98	Target Neighborhood Hits	1039	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

EFHC2_HUMAN
NC score	0.019355 (rank : 92)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	98	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JST6, Q5JST8, Q68DK4, Q8NEI0, Q9H653	Gene names	EFHC2
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member C2.

NFAT5_MOUSE
NC score	0.018519 (rank : 93)	θ value	0.365318 (rank : 49)
Query Neighborhood Hits	98	Target Neighborhood Hits	162	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

CNGB3_MOUSE
NC score	0.017910 (rank : 94)	θ value	0.0961366 (rank : 46)
Query Neighborhood Hits	98	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

ALMS1_HUMAN
NC score	0.016356 (rank : 95)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	98	Target Neighborhood Hits	356	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

DPOLA_MOUSE
NC score	0.016168 (rank : 96)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	98	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	P33609	Gene names	Pola1, Pola
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

TPR_HUMAN
NC score	0.015796 (rank : 97)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	98	Target Neighborhood Hits	1921	Shared Neighborhood Hits	35
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

CF064_MOUSE
NC score	0.015482 (rank : 98)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	98	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K190	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf64 homolog.

ZN451_MOUSE
NC score	0.015454 (rank : 99)	θ value	0.62314 (rank : 54)
Query Neighborhood Hits	98	Target Neighborhood Hits	643	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C0P7	Gene names	Znf451, Zfp451
Domain Architecture	No domain graphic available
Description	Zinc finger protein 451.

GCC2_MOUSE
NC score	0.014908 (rank : 100)	θ value	0.279714 (rank : 48)
Query Neighborhood Hits	98	Target Neighborhood Hits	1619	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

PKHA6_MOUSE
NC score	0.013824 (rank : 101)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	98	Target Neighborhood Hits	591	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

ZW10_HUMAN
NC score	0.013012 (rank : 102)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	98	Target Neighborhood Hits	101	Shared Neighborhood Hits	6
SwissProt Accessions	O43264	Gene names	ZW10
Domain Architecture
Description	Centromere/kinetochore protein zw10 homolog.

HASP_MOUSE
NC score	0.012699 (rank : 103)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	98	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z0R0, Q99MU9, Q9JJJ4	Gene names	Gsg2
Domain Architecture
Description	Serine/threonine-protein kinase Haspin (EC 2.7.11.1) (Haploid germ cell-specific nuclear protein kinase) (Germ cell-specific gene 2 protein).

CCHCR_MOUSE
NC score	0.012611 (rank : 104)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	98	Target Neighborhood Hits	932	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

DPOLA_HUMAN
NC score	0.012480 (rank : 105)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	98	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	P09884, Q86UQ7	Gene names	POLA1, POLA
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

WDHD1_MOUSE
NC score	0.012439 (rank : 106)	θ value	0.813845 (rank : 55)
Query Neighborhood Hits	98	Target Neighborhood Hits	414	Shared Neighborhood Hits	4
SwissProt Accessions	P59328, Q6P408	Gene names	Wdhd1, And1
Domain Architecture	No domain graphic available
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

EEA1_HUMAN
NC score	0.012337 (rank : 107)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	98	Target Neighborhood Hits	1796	Shared Neighborhood Hits	33
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

TCEA1_HUMAN
NC score	0.011946 (rank : 108)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	98	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	P23193, Q15563, Q6FG87	Gene names	TCEA1, TFIIS
Domain Architecture
Description	Transcription elongation factor A protein 1 (Transcription elongation factor S-II protein 1) (Transcription elongation factor TFIIS.o).

STX12_HUMAN
NC score	0.011832 (rank : 109)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	98	Target Neighborhood Hits	226	Shared Neighborhood Hits	7
SwissProt Accessions	Q86Y82, O95564	Gene names	STX12
Domain Architecture
Description	Syntaxin-12.

SIA7A_MOUSE
NC score	0.011537 (rank : 110)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	98	Target Neighborhood Hits	203	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZ39, Q9JJP5	Gene names	St6galnac1, Siat7a
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

STX12_MOUSE
NC score	0.011063 (rank : 111)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	98	Target Neighborhood Hits	283	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ER00, Q3UIV9, Q921T9	Gene names	Stx12
Domain Architecture
Description	Syntaxin-12.

ATF1_MOUSE
NC score	0.011059 (rank : 112)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	98	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	P81269	Gene names	Atf1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-1 (Activating transcription factor 1) (TCR-ATF1).

SPC25_MOUSE
NC score	0.011005 (rank : 113)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	98	Target Neighborhood Hits	241	Shared Neighborhood Hits	11
SwissProt Accessions	Q3UA16, Q9D021, Q9D1K6	Gene names	Spbc25
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc25.

EZRI_HUMAN
NC score	0.009924 (rank : 114)	θ value	1.06291 (rank : 57)
Query Neighborhood Hits	98	Target Neighborhood Hits	663	Shared Neighborhood Hits	17
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

DHX34_MOUSE
NC score	0.008578 (rank : 115)	θ value	1.06291 (rank : 56)
Query Neighborhood Hits	98	Target Neighborhood Hits	235	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DBV3	Gene names	Dhx34, Ddx34, Kiaa0134
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

UACA_HUMAN
NC score	0.008093 (rank : 116)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	98	Target Neighborhood Hits	1622	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

TUFT1_MOUSE
NC score	0.007282 (rank : 117)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	98	Target Neighborhood Hits	732	Shared Neighborhood Hits	16
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

GOGA3_MOUSE
NC score	0.006460 (rank : 118)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	98	Target Neighborhood Hits	1437	Shared Neighborhood Hits	23
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

SYTL1_MOUSE
NC score	0.006453 (rank : 119)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	98	Target Neighborhood Hits	314	Shared Neighborhood Hits	7
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

COIA1_MOUSE
NC score	0.006053 (rank : 120)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	98	Target Neighborhood Hits	481	Shared Neighborhood Hits	6
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

DEN2A_MOUSE
NC score	0.005566 (rank : 121)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	98	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C4S8, Q3TJU2, Q3TUG3, Q3UXA3	Gene names	Dennd2a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

WWP2_HUMAN
NC score	0.001297 (rank : 122)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	98	Target Neighborhood Hits	177	Shared Neighborhood Hits	3
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

POT14_HUMAN
NC score	0.000992 (rank : 123)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	98	Target Neighborhood Hits	403	Shared Neighborhood Hits	5
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

SNRK_MOUSE
NC score	0.000017 (rank : 124)	θ value	0.21417 (rank : 47)
Query Neighborhood Hits	98	Target Neighborhood Hits	849	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VDU5, Q91WX6	Gene names	Snrk
Domain Architecture	No domain graphic available
Description	SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1- related kinase).

SNRK_HUMAN
NC score	-0.000377 (rank : 125)	θ value	0.47712 (rank : 50)
Query Neighborhood Hits	98	Target Neighborhood Hits	855	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NRH2, Q14706, Q68D15, Q6IQ46, Q9NXI7	Gene names	SNRK, KIAA0096, SNFRK
Domain Architecture	No domain graphic available
Description	SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1- related kinase).

ZBT40_HUMAN
NC score	-0.000720 (rank : 126)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	98	Target Neighborhood Hits	949	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.

ZN690_HUMAN
NC score	-0.003547 (rank : 127)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	98	Target Neighborhood Hits	777	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IWY8, Q32M75, Q32M76, Q8NA40	Gene names	ZNF690
Domain Architecture	No domain graphic available
Description	Zinc finger protein 690.

O2T33_HUMAN
NC score	-0.004220 (rank : 128)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	98	Target Neighborhood Hits	689	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NG76	Gene names	OR2T33
Domain Architecture	No domain graphic available
Description	Olfactory receptor 2T33 (Olfactory receptor OR1-56).