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Network neighborhood for query Sequence : SMCA1_HUMAN

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SMCA1_HUMAN
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SMCA1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	105	Target Neighborhood Hits	105	Shared Neighborhood Hits	105
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMCA1_MOUSE
θ value	0 (rank : 2)	NC score	0.996003 (rank : 4)
Query Neighborhood Hits	105	Target Neighborhood Hits	117	Shared Neighborhood Hits	77
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

SMCA5_HUMAN
θ value	0 (rank : 3)	NC score	0.997049 (rank : 3)
Query Neighborhood Hits	105	Target Neighborhood Hits	76	Shared Neighborhood Hits	54
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

SMCA5_MOUSE
θ value	0 (rank : 4)	NC score	0.997153 (rank : 2)
Query Neighborhood Hits	105	Target Neighborhood Hits	80	Shared Neighborhood Hits	55
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

SMCA4_HUMAN
θ value	3.29472e-127 (rank : 5)	NC score	0.904779 (rank : 23)
Query Neighborhood Hits	105	Target Neighborhood Hits	597	Shared Neighborhood Hits	58
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

CHD2_HUMAN
θ value	8.11517e-126 (rank : 6)	NC score	0.942993 (rank : 7)
Query Neighborhood Hits	105	Target Neighborhood Hits	360	Shared Neighborhood Hits	46
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CHD1_MOUSE
θ value	1.29561e-123 (rank : 7)	NC score	0.942738 (rank : 9)
Query Neighborhood Hits	105	Target Neighborhood Hits	266	Shared Neighborhood Hits	43
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_HUMAN
θ value	8.39787e-123 (rank : 8)	NC score	0.938939 (rank : 12)
Query Neighborhood Hits	105	Target Neighborhood Hits	337	Shared Neighborhood Hits	48
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

SMCA2_HUMAN
θ value	1.58377e-121 (rank : 9)	NC score	0.915459 (rank : 22)
Query Neighborhood Hits	105	Target Neighborhood Hits	503	Shared Neighborhood Hits	55
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

CHD3_HUMAN
θ value	1.34075e-120 (rank : 10)	NC score	0.881097 (rank : 24)
Query Neighborhood Hits	105	Target Neighborhood Hits	397	Shared Neighborhood Hits	47
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD5_HUMAN
θ value	3.30237e-119 (rank : 11)	NC score	0.878886 (rank : 26)
Query Neighborhood Hits	105	Target Neighborhood Hits	349	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHD4_HUMAN
θ value	4.03687e-117 (rank : 12)	NC score	0.879050 (rank : 25)
Query Neighborhood Hits	105	Target Neighborhood Hits	365	Shared Neighborhood Hits	47
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	4.03687e-117 (rank : 13)	NC score	0.875545 (rank : 27)
Query Neighborhood Hits	105	Target Neighborhood Hits	408	Shared Neighborhood Hits	48
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD6_HUMAN
θ value	5.64607e-111 (rank : 14)	NC score	0.936025 (rank : 13)
Query Neighborhood Hits	105	Target Neighborhood Hits	342	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CHD8_HUMAN
θ value	8.15288e-110 (rank : 15)	NC score	0.942808 (rank : 8)
Query Neighborhood Hits	105	Target Neighborhood Hits	235	Shared Neighborhood Hits	45
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CHD9_MOUSE
θ value	1.39067e-109 (rank : 16)	NC score	0.926936 (rank : 19)
Query Neighborhood Hits	105	Target Neighborhood Hits	427	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

CHD9_HUMAN
θ value	1.81628e-109 (rank : 17)	NC score	0.931488 (rank : 16)
Query Neighborhood Hits	105	Target Neighborhood Hits	343	Shared Neighborhood Hits	46
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

SMRCD_HUMAN
θ value	3.11973e-85 (rank : 18)	NC score	0.951852 (rank : 6)
Query Neighborhood Hits	105	Target Neighborhood Hits	117	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

SMRCD_MOUSE
θ value	9.07703e-85 (rank : 19)	NC score	0.952115 (rank : 5)
Query Neighborhood Hits	105	Target Neighborhood Hits	96	Shared Neighborhood Hits	40
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

ERCC6_HUMAN
θ value	6.10265e-73 (rank : 20)	NC score	0.940883 (rank : 10)
Query Neighborhood Hits	105	Target Neighborhood Hits	247	Shared Neighborhood Hits	45
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

INOC1_HUMAN
θ value	4.09345e-69 (rank : 21)	NC score	0.920765 (rank : 21)
Query Neighborhood Hits	105	Target Neighborhood Hits	181	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

INOC1_MOUSE
θ value	1.5555e-68 (rank : 22)	NC score	0.920806 (rank : 20)
Query Neighborhood Hits	105	Target Neighborhood Hits	178	Shared Neighborhood Hits	43
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

RA54B_HUMAN
θ value	1.00825e-67 (rank : 23)	NC score	0.934249 (rank : 14)
Query Neighborhood Hits	105	Target Neighborhood Hits	54	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

BTAF1_HUMAN
θ value	6.11685e-65 (rank : 24)	NC score	0.940822 (rank : 11)
Query Neighborhood Hits	105	Target Neighborhood Hits	97	Shared Neighborhood Hits	38
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

RA54B_MOUSE
θ value	1.36269e-64 (rank : 25)	NC score	0.932576 (rank : 15)
Query Neighborhood Hits	105	Target Neighborhood Hits	59	Shared Neighborhood Hits	44
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

RAD54_MOUSE
θ value	1.78386e-56 (rank : 26)	NC score	0.928163 (rank : 18)
Query Neighborhood Hits	105	Target Neighborhood Hits	51	Shared Neighborhood Hits	38
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

RAD54_HUMAN
θ value	2.32979e-56 (rank : 27)	NC score	0.928701 (rank : 17)
Query Neighborhood Hits	105	Target Neighborhood Hits	51	Shared Neighborhood Hits	38
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

EP400_MOUSE
θ value	8.02596e-49 (rank : 28)	NC score	0.825050 (rank : 32)
Query Neighborhood Hits	105	Target Neighborhood Hits	592	Shared Neighborhood Hits	48
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

EP400_HUMAN
θ value	1.04822e-48 (rank : 29)	NC score	0.832034 (rank : 31)
Query Neighborhood Hits	105	Target Neighborhood Hits	556	Shared Neighborhood Hits	45
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

TTF2_HUMAN
θ value	2.58786e-39 (rank : 30)	NC score	0.861380 (rank : 28)
Query Neighborhood Hits	105	Target Neighborhood Hits	98	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

TTF2_MOUSE
θ value	9.52487e-34 (rank : 31)	NC score	0.818727 (rank : 33)
Query Neighborhood Hits	105	Target Neighborhood Hits	364	Shared Neighborhood Hits	51
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

SMAL1_HUMAN
θ value	1.85889e-29 (rank : 32)	NC score	0.835725 (rank : 30)
Query Neighborhood Hits	105	Target Neighborhood Hits	174	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

SMAL1_MOUSE
θ value	9.54697e-26 (rank : 33)	NC score	0.843082 (rank : 29)
Query Neighborhood Hits	105	Target Neighborhood Hits	157	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

ATRX_MOUSE
θ value	6.18819e-25 (rank : 34)	NC score	0.694918 (rank : 36)
Query Neighborhood Hits	105	Target Neighborhood Hits	682	Shared Neighborhood Hits	51
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

ATRX_HUMAN
θ value	1.80048e-24 (rank : 35)	NC score	0.676145 (rank : 37)
Query Neighborhood Hits	105	Target Neighborhood Hits	842	Shared Neighborhood Hits	62
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

SMRA3_HUMAN
θ value	3.51386e-20 (rank : 36)	NC score	0.722258 (rank : 35)
Query Neighborhood Hits	105	Target Neighborhood Hits	265	Shared Neighborhood Hits	39
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

SMRA3_MOUSE
θ value	1.74391e-19 (rank : 37)	NC score	0.723678 (rank : 34)
Query Neighborhood Hits	105	Target Neighborhood Hits	267	Shared Neighborhood Hits	39
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

FANCM_HUMAN
θ value	0.0330416 (rank : 38)	NC score	0.059842 (rank : 84)
Query Neighborhood Hits	105	Target Neighborhood Hits	210	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

MYH11_HUMAN
θ value	0.0330416 (rank : 39)	NC score	0.014373 (rank : 128)
Query Neighborhood Hits	105	Target Neighborhood Hits	1806	Shared Neighborhood Hits	51
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

POF1B_HUMAN
θ value	0.0431538 (rank : 40)	NC score	0.016836 (rank : 125)
Query Neighborhood Hits	105	Target Neighborhood Hits	494	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WVV4, Q5H9E9, Q5H9F0, Q8NG12, Q9H5Y2, Q9H738, Q9H744	Gene names	POF1B
Domain Architecture	No domain graphic available
Description	Protein POF1B (Premature ovarian failure protein 1B).

DDX49_MOUSE
θ value	0.0563607 (rank : 41)	NC score	0.035118 (rank : 109)
Query Neighborhood Hits	105	Target Neighborhood Hits	119	Shared Neighborhood Hits	22
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

TNNT2_HUMAN
θ value	0.0736092 (rank : 42)	NC score	0.038835 (rank : 108)
Query Neighborhood Hits	105	Target Neighborhood Hits	433	Shared Neighborhood Hits	21
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

PCLO_MOUSE
θ value	0.0961366 (rank : 43)	NC score	0.039244 (rank : 107)
Query Neighborhood Hits	105	Target Neighborhood Hits	2275	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PSMD1_HUMAN
θ value	0.163984 (rank : 44)	NC score	0.031230 (rank : 110)
Query Neighborhood Hits	105	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	Q99460, Q53TI2, Q6GMU5, Q6P2P4, Q6PJM7, Q6PKG9, Q86VU1, Q8IV79	Gene names	PSMD1
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112).

PSMD1_MOUSE
θ value	0.163984 (rank : 45)	NC score	0.031125 (rank : 111)
Query Neighborhood Hits	105	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	Q3TXS7	Gene names	Psmd1
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1).

DDX23_HUMAN
θ value	0.21417 (rank : 46)	NC score	0.057095 (rank : 89)
Query Neighborhood Hits	105	Target Neighborhood Hits	486	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

CJ049_HUMAN
θ value	0.279714 (rank : 47)	NC score	0.039816 (rank : 106)
Query Neighborhood Hits	105	Target Neighborhood Hits	90	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WVF2	Gene names	C10orf49
Domain Architecture	No domain graphic available
Description	Protein C10orf49 precursor.

DDX41_HUMAN
θ value	0.365318 (rank : 48)	NC score	0.062564 (rank : 78)
Query Neighborhood Hits	105	Target Neighborhood Hits	111	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
θ value	0.365318 (rank : 49)	NC score	0.066164 (rank : 68)
Query Neighborhood Hits	105	Target Neighborhood Hits	115	Shared Neighborhood Hits	29
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

PL10_MOUSE
θ value	0.365318 (rank : 50)	NC score	0.068311 (rank : 63)
Query Neighborhood Hits	105	Target Neighborhood Hits	120	Shared Neighborhood Hits	28
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

TNNT2_MOUSE
θ value	0.365318 (rank : 51)	NC score	0.027577 (rank : 117)
Query Neighborhood Hits	105	Target Neighborhood Hits	395	Shared Neighborhood Hits	19
SwissProt Accessions	P50752, Q64360, Q64377	Gene names	Tnnt2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

DDX49_HUMAN
θ value	0.47712 (rank : 52)	NC score	0.029431 (rank : 113)
Query Neighborhood Hits	105	Target Neighborhood Hits	223	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

PCLO_HUMAN
θ value	0.47712 (rank : 53)	NC score	0.030946 (rank : 112)
Query Neighborhood Hits	105	Target Neighborhood Hits	2046	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

CAF1A_MOUSE
θ value	0.62314 (rank : 54)	NC score	0.024009 (rank : 120)
Query Neighborhood Hits	105	Target Neighborhood Hits	736	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

ANR26_MOUSE
θ value	0.813845 (rank : 55)	NC score	0.012070 (rank : 136)
Query Neighborhood Hits	105	Target Neighborhood Hits	1554	Shared Neighborhood Hits	45
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

DDX3X_HUMAN
θ value	0.813845 (rank : 56)	NC score	0.063518 (rank : 74)
Query Neighborhood Hits	105	Target Neighborhood Hits	122	Shared Neighborhood Hits	28
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX3X_MOUSE
θ value	0.813845 (rank : 57)	NC score	0.063710 (rank : 73)
Query Neighborhood Hits	105	Target Neighborhood Hits	117	Shared Neighborhood Hits	28
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

LBN_MOUSE
θ value	1.38821 (rank : 58)	NC score	0.021115 (rank : 121)
Query Neighborhood Hits	105	Target Neighborhood Hits	310	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K1G2, Q8BRF3	Gene names	Evc2, Lbn
Domain Architecture	No domain graphic available
Description	Limbin.

LMBL3_MOUSE
θ value	1.38821 (rank : 59)	NC score	0.013829 (rank : 129)
Query Neighborhood Hits	105	Target Neighborhood Hits	212	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BLB7, Q641L7, Q6ZPI2, Q8C0G4	Gene names	L3mbtl3
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein).

SPTN5_HUMAN
θ value	1.38821 (rank : 60)	NC score	0.012550 (rank : 133)
Query Neighborhood Hits	105	Target Neighborhood Hits	674	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

STK10_HUMAN
θ value	1.38821 (rank : 61)	NC score	0.007918 (rank : 149)
Query Neighborhood Hits	105	Target Neighborhood Hits	1921	Shared Neighborhood Hits	46
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

DDX3Y_HUMAN
θ value	1.81305 (rank : 62)	NC score	0.059887 (rank : 82)
Query Neighborhood Hits	105	Target Neighborhood Hits	121	Shared Neighborhood Hits	28
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

GP179_HUMAN
θ value	1.81305 (rank : 63)	NC score	0.017135 (rank : 124)
Query Neighborhood Hits	105	Target Neighborhood Hits	372	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

CEP63_HUMAN
θ value	2.36792 (rank : 64)	NC score	0.006199 (rank : 152)
Query Neighborhood Hits	105	Target Neighborhood Hits	1005	Shared Neighborhood Hits	34
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

SYCC_MOUSE
θ value	2.36792 (rank : 65)	NC score	0.016809 (rank : 126)
Query Neighborhood Hits	105	Target Neighborhood Hits	63	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ER72, O88303, Q8BP81, Q8CAY7, Q8CCE3, Q8K0S4, Q9ER68	Gene names	Cars
Domain Architecture
Description	Cysteinyl-tRNA synthetase, cytoplasmic (EC 6.1.1.16) (Cysteine--tRNA ligase) (CysRS).

UBXD2_MOUSE
θ value	2.36792 (rank : 66)	NC score	0.011598 (rank : 137)
Query Neighborhood Hits	105	Target Neighborhood Hits	183	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VCH8, Q8BW17	Gene names	Ubxd2, Ubxdc1
Domain Architecture
Description	UBX domain-containing protein 2.

CCHCR_MOUSE
θ value	3.0926 (rank : 67)	NC score	0.007926 (rank : 148)
Query Neighborhood Hits	105	Target Neighborhood Hits	932	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

ZN294_HUMAN
θ value	3.0926 (rank : 68)	NC score	0.012351 (rank : 134)
Query Neighborhood Hits	105	Target Neighborhood Hits	86	Shared Neighborhood Hits	4
SwissProt Accessions	O94822, Q9H8M4, Q9NUY5, Q9P0E9	Gene names	ZNF294, C21orf10, C21orf98, KIAA0714
Domain Architecture
Description	Zinc finger protein 294.

ZN628_HUMAN
θ value	3.0926 (rank : 69)	NC score	-0.004360 (rank : 164)
Query Neighborhood Hits	105	Target Neighborhood Hits	814	Shared Neighborhood Hits	3
SwissProt Accessions	Q5EBL2, Q86X34	Gene names	ZNF628
Domain Architecture	No domain graphic available
Description	Zinc finger protein 628.

ANR12_HUMAN
θ value	4.03905 (rank : 70)	NC score	0.010231 (rank : 139)
Query Neighborhood Hits	105	Target Neighborhood Hits	1081	Shared Neighborhood Hits	32
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

GRK4_HUMAN
θ value	4.03905 (rank : 71)	NC score	-0.002080 (rank : 163)
Query Neighborhood Hits	105	Target Neighborhood Hits	822	Shared Neighborhood Hits	8
SwissProt Accessions	P32298, O00641, O00642, Q13293, Q13294, Q13295, Q14453, Q14725, Q15313, Q15314, Q15315, Q15316	Gene names	GRK4, GPRK2L, GPRK4
Domain Architecture
Description	G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1).

MLL3_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.058706 (rank : 87)
Query Neighborhood Hits	105	Target Neighborhood Hits	1644	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PZRN4_HUMAN
θ value	4.03905 (rank : 73)	NC score	0.003798 (rank : 160)
Query Neighborhood Hits	105	Target Neighborhood Hits	438	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

SDPR_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.024323 (rank : 119)
Query Neighborhood Hits	105	Target Neighborhood Hits	337	Shared Neighborhood Hits	25
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

TNNT3_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.019880 (rank : 122)
Query Neighborhood Hits	105	Target Neighborhood Hits	327	Shared Neighborhood Hits	16
SwissProt Accessions	P45378, Q12975, Q12976, Q12977, Q12978, Q86TH6	Gene names	TNNT3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT) (Beta TnTF).

BRD4_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.027504 (rank : 118)
Query Neighborhood Hits	105	Target Neighborhood Hits	851	Shared Neighborhood Hits	30
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CE290_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.008334 (rank : 145)
Query Neighborhood Hits	105	Target Neighborhood Hits	1553	Shared Neighborhood Hits	42
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

NFM_MOUSE
θ value	5.27518 (rank : 78)	NC score	0.007396 (rank : 150)
Query Neighborhood Hits	105	Target Neighborhood Hits	1159	Shared Neighborhood Hits	34
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

PEPL_MOUSE
θ value	5.27518 (rank : 79)	NC score	0.012109 (rank : 135)
Query Neighborhood Hits	105	Target Neighborhood Hits	1105	Shared Neighborhood Hits	36
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

PLEC1_HUMAN
θ value	5.27518 (rank : 80)	NC score	0.006165 (rank : 153)
Query Neighborhood Hits	105	Target Neighborhood Hits	1326	Shared Neighborhood Hits	32
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

RADI_MOUSE
θ value	5.27518 (rank : 81)	NC score	0.005753 (rank : 154)
Query Neighborhood Hits	105	Target Neighborhood Hits	773	Shared Neighborhood Hits	25
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

SH21B_MOUSE
θ value	5.27518 (rank : 82)	NC score	0.009276 (rank : 142)
Query Neighborhood Hits	105	Target Neighborhood Hits	101	Shared Neighborhood Hits	3
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

UB7I1_HUMAN
θ value	5.27518 (rank : 83)	NC score	0.010692 (rank : 138)
Query Neighborhood Hits	105	Target Neighborhood Hits	177	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

ACAD9_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.004440 (rank : 159)
Query Neighborhood Hits	105	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H845, Q8WXX3	Gene names	ACAD9
Domain Architecture
Description	Acyl-CoA dehydrogenase family member 9, mitochondrial precursor (EC 1.3.99.-) (ACAD-9).

BRD4_MOUSE
θ value	6.88961 (rank : 85)	NC score	0.029309 (rank : 114)
Query Neighborhood Hits	105	Target Neighborhood Hits	845	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CAF1A_HUMAN
θ value	6.88961 (rank : 86)	NC score	0.017850 (rank : 123)
Query Neighborhood Hits	105	Target Neighborhood Hits	750	Shared Neighborhood Hits	29
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

FLIP1_MOUSE
θ value	6.88961 (rank : 87)	NC score	0.008804 (rank : 144)
Query Neighborhood Hits	105	Target Neighborhood Hits	1176	Shared Neighborhood Hits	37
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

IMMT_HUMAN
θ value	6.88961 (rank : 88)	NC score	0.010217 (rank : 140)
Query Neighborhood Hits	105	Target Neighborhood Hits	494	Shared Neighborhood Hits	25
SwissProt Accessions	Q16891, Q14539, Q15092, Q68D41, Q69HW5, Q6IBL0, Q7Z3X1, Q8TAJ5, Q9P0V2	Gene names	IMMT, HMP, PIG4
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin) (p87/89) (Proliferation-inducing gene 4 protein).

KI21A_HUMAN
θ value	6.88961 (rank : 89)	NC score	0.013090 (rank : 132)
Query Neighborhood Hits	105	Target Neighborhood Hits	1543	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

MRCKB_MOUSE
θ value	6.88961 (rank : 90)	NC score	0.003033 (rank : 161)
Query Neighborhood Hits	105	Target Neighborhood Hits	2180	Shared Neighborhood Hits	43
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

SETD2_HUMAN
θ value	6.88961 (rank : 91)	NC score	0.013721 (rank : 130)
Query Neighborhood Hits	105	Target Neighborhood Hits	412	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SYCC_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.009988 (rank : 141)
Query Neighborhood Hits	105	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	P49589, Q53XI8, Q9HD24, Q9HD25	Gene names	CARS
Domain Architecture
Description	Cysteinyl-tRNA synthetase, cytoplasmic (EC 6.1.1.16) (Cysteine--tRNA ligase) (CysRS).

TRHY_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.009004 (rank : 143)
Query Neighborhood Hits	105	Target Neighborhood Hits	1385	Shared Neighborhood Hits	35
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

WBP11_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.008112 (rank : 146)
Query Neighborhood Hits	105	Target Neighborhood Hits	354	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

BPAEA_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.004981 (rank : 157)
Query Neighborhood Hits	105	Target Neighborhood Hits	1369	Shared Neighborhood Hits	30
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CEP55_HUMAN
θ value	8.99809 (rank : 96)	NC score	0.004492 (rank : 158)
Query Neighborhood Hits	105	Target Neighborhood Hits	504	Shared Neighborhood Hits	23
SwissProt Accessions	Q53EZ4, Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7	Gene names	CEP55, C10orf3, URCC6
Domain Architecture	No domain graphic available
Description	Centrosome protein 55 (Up-regulated in colon cancer 6).

DDX48_HUMAN
θ value	8.99809 (rank : 97)	NC score	0.029136 (rank : 116)
Query Neighborhood Hits	105	Target Neighborhood Hits	102	Shared Neighborhood Hits	19
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
θ value	8.99809 (rank : 98)	NC score	0.029139 (rank : 115)
Query Neighborhood Hits	105	Target Neighborhood Hits	102	Shared Neighborhood Hits	19
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

FA47A_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.005526 (rank : 156)
Query Neighborhood Hits	105	Target Neighborhood Hits	451	Shared Neighborhood Hits	11
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

K1210_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.014685 (rank : 127)
Query Neighborhood Hits	105	Target Neighborhood Hits	219	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

LBN_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.013449 (rank : 131)
Query Neighborhood Hits	105	Target Neighborhood Hits	308	Shared Neighborhood Hits	16
SwissProt Accessions	Q86UK5, Q86YT3, Q86YT4, Q8NG49	Gene names	EVC2, LBN
Domain Architecture	No domain graphic available
Description	Limbin.

MACOI_MOUSE
θ value	8.99809 (rank : 102)	NC score	0.005697 (rank : 155)
Query Neighborhood Hits	105	Target Neighborhood Hits	620	Shared Neighborhood Hits	29
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

PER2_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.008014 (rank : 147)
Query Neighborhood Hits	105	Target Neighborhood Hits	170	Shared Neighborhood Hits	7
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

SH3K1_MOUSE
θ value	8.99809 (rank : 104)	NC score	0.007193 (rank : 151)
Query Neighborhood Hits	105	Target Neighborhood Hits	332	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

TITIN_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.000959 (rank : 162)
Query Neighborhood Hits	105	Target Neighborhood Hits	2923	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

AIRE_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.099499 (rank : 39)
Query Neighborhood Hits	105	Target Neighborhood Hits	144	Shared Neighborhood Hits	8
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.101238 (rank : 38)
Query Neighborhood Hits	105	Target Neighborhood Hits	196	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

BAZ1A_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.074139 (rank : 54)
Query Neighborhood Hits	105	Target Neighborhood Hits	693	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ1B_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.072185 (rank : 59)
Query Neighborhood Hits	105	Target Neighborhood Hits	701	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ1B_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.079380 (rank : 51)
Query Neighborhood Hits	105	Target Neighborhood Hits	394	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BAZ2A_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.054109 (rank : 96)
Query Neighborhood Hits	105	Target Neighborhood Hits	780	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2A_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.054116 (rank : 95)
Query Neighborhood Hits	105	Target Neighborhood Hits	744	Shared Neighborhood Hits	27
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BAZ2B_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.058765 (rank : 86)
Query Neighborhood Hits	105	Target Neighborhood Hits	803	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BPTF_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.091976 (rank : 42)
Query Neighborhood Hits	105	Target Neighborhood Hits	786	Shared Neighborhood Hits	29
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BRD1_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.051070 (rank : 103)
Query Neighborhood Hits	105	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

CBX1_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.068168 (rank : 65)
Query Neighborhood Hits	105	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.068168 (rank : 66)
Query Neighborhood Hits	105	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

CBX3_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.059894 (rank : 81)
Query Neighborhood Hits	105	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

CBX3_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.063044 (rank : 76)
Query Neighborhood Hits	105	Target Neighborhood Hits	39	Shared Neighborhood Hits	10
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

CBX5_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.082517 (rank : 49)
Query Neighborhood Hits	105	Target Neighborhood Hits	70	Shared Neighborhood Hits	12
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CBX5_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.073673 (rank : 55)
Query Neighborhood Hits	105	Target Neighborhood Hits	67	Shared Neighborhood Hits	11
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

CBX7_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.059874 (rank : 83)
Query Neighborhood Hits	105	Target Neighborhood Hits	48	Shared Neighborhood Hits	8
SwissProt Accessions	O95931, Q86T17	Gene names	CBX7
Domain Architecture
Description	Chromobox protein homolog 7.

CBX7_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.063204 (rank : 75)
Query Neighborhood Hits	105	Target Neighborhood Hits	38	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VDS3	Gene names	Cbx7, D15Ertd417e
Domain Architecture
Description	Chromobox protein homolog 7.

DPF1_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.055954 (rank : 91)
Query Neighborhood Hits	105	Target Neighborhood Hits	136	Shared Neighborhood Hits	5
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

IWS1_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.064236 (rank : 72)
Query Neighborhood Hits	105	Target Neighborhood Hits	1241	Shared Neighborhood Hits	39
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.072438 (rank : 56)
Query Neighborhood Hits	105	Target Neighborhood Hits	1258	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LEO1_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.062951 (rank : 77)
Query Neighborhood Hits	105	Target Neighborhood Hits	958	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LEO1_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.065117 (rank : 70)
Query Neighborhood Hits	105	Target Neighborhood Hits	946	Shared Neighborhood Hits	37
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LY10_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.067804 (rank : 67)
Query Neighborhood Hits	105	Target Neighborhood Hits	151	Shared Neighborhood Hits	11
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

MLL2_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.050723 (rank : 104)
Query Neighborhood Hits	105	Target Neighborhood Hits	1788	Shared Neighborhood Hits	39
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL3_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.051706 (rank : 100)
Query Neighborhood Hits	105	Target Neighborhood Hits	1399	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NIPBL_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.065301 (rank : 69)
Query Neighborhood Hits	105	Target Neighborhood Hits	1311	Shared Neighborhood Hits	44
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.059133 (rank : 85)
Query Neighborhood Hits	105	Target Neighborhood Hits	1041	Shared Neighborhood Hits	38
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NSD1_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.062091 (rank : 80)
Query Neighborhood Hits	105	Target Neighborhood Hits	427	Shared Neighborhood Hits	13
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.064297 (rank : 71)
Query Neighborhood Hits	105	Target Neighborhood Hits	472	Shared Neighborhood Hits	16
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PB1_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.056438 (rank : 90)
Query Neighborhood Hits	105	Target Neighborhood Hits	261	Shared Neighborhood Hits	5
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

PF21A_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.085292 (rank : 47)
Query Neighborhood Hits	105	Target Neighborhood Hits	303	Shared Neighborhood Hits	9
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.086458 (rank : 46)
Query Neighborhood Hits	105	Target Neighborhood Hits	285	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21B_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.088271 (rank : 45)
Query Neighborhood Hits	105	Target Neighborhood Hits	197	Shared Neighborhood Hits	7
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.089364 (rank : 43)
Query Neighborhood Hits	105	Target Neighborhood Hits	278	Shared Neighborhood Hits	10
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF10_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.052324 (rank : 99)
Query Neighborhood Hits	105	Target Neighborhood Hits	151	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.051377 (rank : 101)
Query Neighborhood Hits	105	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PHF12_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.093394 (rank : 41)
Query Neighborhood Hits	105	Target Neighborhood Hits	174	Shared Neighborhood Hits	8
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.093620 (rank : 40)
Query Neighborhood Hits	105	Target Neighborhood Hits	172	Shared Neighborhood Hits	9
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF20_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.053034 (rank : 98)
Query Neighborhood Hits	105	Target Neighborhood Hits	513	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PKCB1_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.089339 (rank : 44)
Query Neighborhood Hits	105	Target Neighborhood Hits	488	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

RBBP6_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.053098 (rank : 97)
Query Neighborhood Hits	105	Target Neighborhood Hits	1135	Shared Neighborhood Hits	38
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.054335 (rank : 94)
Query Neighborhood Hits	105	Target Neighborhood Hits	1014	Shared Neighborhood Hits	35
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RSF1_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.076208 (rank : 52)
Query Neighborhood Hits	105	Target Neighborhood Hits	539	Shared Neighborhood Hits	25
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SP110_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.075889 (rank : 53)
Query Neighborhood Hits	105	Target Neighborhood Hits	141	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

TCAL5_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.055486 (rank : 92)
Query Neighborhood Hits	105	Target Neighborhood Hits	806	Shared Neighborhood Hits	33
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TGON2_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.070128 (rank : 62)
Query Neighborhood Hits	105	Target Neighborhood Hits	1037	Shared Neighborhood Hits	28
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TIF1A_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.068183 (rank : 64)
Query Neighborhood Hits	105	Target Neighborhood Hits	327	Shared Neighborhood Hits	11
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1A_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.071672 (rank : 60)
Query Neighborhood Hits	105	Target Neighborhood Hits	307	Shared Neighborhood Hits	13
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1G_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.062555 (rank : 79)
Query Neighborhood Hits	105	Target Neighborhood Hits	410	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.070172 (rank : 61)
Query Neighborhood Hits	105	Target Neighborhood Hits	498	Shared Neighborhood Hits	16
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TRI66_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.072296 (rank : 58)
Query Neighborhood Hits	105	Target Neighborhood Hits	479	Shared Neighborhood Hits	20
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.072423 (rank : 57)
Query Neighborhood Hits	105	Target Neighborhood Hits	491	Shared Neighborhood Hits	21
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TXND2_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.057490 (rank : 88)
Query Neighborhood Hits	105	Target Neighborhood Hits	828	Shared Neighborhood Hits	36
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

UHRF1_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.051227 (rank : 102)
Query Neighborhood Hits	105	Target Neighborhood Hits	272	Shared Neighborhood Hits	9
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF2_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.054744 (rank : 93)
Query Neighborhood Hits	105	Target Neighborhood Hits	269	Shared Neighborhood Hits	9
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.050523 (rank : 105)
Query Neighborhood Hits	105	Target Neighborhood Hits	275	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

ZMY11_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.082841 (rank : 48)
Query Neighborhood Hits	105	Target Neighborhood Hits	201	Shared Neighborhood Hits	16
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

ZMY11_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.080367 (rank : 50)
Query Neighborhood Hits	105	Target Neighborhood Hits	198	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

Hits sorted by NC score

SMCA1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	105	Target Neighborhood Hits	105	Shared Neighborhood Hits	105
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMCA5_MOUSE
NC score	0.997153 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	105	Target Neighborhood Hits	80	Shared Neighborhood Hits	55
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

SMCA5_HUMAN
NC score	0.997049 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	105	Target Neighborhood Hits	76	Shared Neighborhood Hits	54
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

SMCA1_MOUSE
NC score	0.996003 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	105	Target Neighborhood Hits	117	Shared Neighborhood Hits	77
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

SMRCD_MOUSE
NC score	0.952115 (rank : 5)	θ value	9.07703e-85 (rank : 19)
Query Neighborhood Hits	105	Target Neighborhood Hits	96	Shared Neighborhood Hits	40
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

SMRCD_HUMAN
NC score	0.951852 (rank : 6)	θ value	3.11973e-85 (rank : 18)
Query Neighborhood Hits	105	Target Neighborhood Hits	117	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

CHD2_HUMAN
NC score	0.942993 (rank : 7)	θ value	8.11517e-126 (rank : 6)
Query Neighborhood Hits	105	Target Neighborhood Hits	360	Shared Neighborhood Hits	46
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CHD8_HUMAN
NC score	0.942808 (rank : 8)	θ value	8.15288e-110 (rank : 15)
Query Neighborhood Hits	105	Target Neighborhood Hits	235	Shared Neighborhood Hits	45
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CHD1_MOUSE
NC score	0.942738 (rank : 9)	θ value	1.29561e-123 (rank : 7)
Query Neighborhood Hits	105	Target Neighborhood Hits	266	Shared Neighborhood Hits	43
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

ERCC6_HUMAN
NC score	0.940883 (rank : 10)	θ value	6.10265e-73 (rank : 20)
Query Neighborhood Hits	105	Target Neighborhood Hits	247	Shared Neighborhood Hits	45
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

BTAF1_HUMAN
NC score	0.940822 (rank : 11)	θ value	6.11685e-65 (rank : 24)
Query Neighborhood Hits	105	Target Neighborhood Hits	97	Shared Neighborhood Hits	38
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

CHD1_HUMAN
NC score	0.938939 (rank : 12)	θ value	8.39787e-123 (rank : 8)
Query Neighborhood Hits	105	Target Neighborhood Hits	337	Shared Neighborhood Hits	48
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD6_HUMAN
NC score	0.936025 (rank : 13)	θ value	5.64607e-111 (rank : 14)
Query Neighborhood Hits	105	Target Neighborhood Hits	342	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

RA54B_HUMAN
NC score	0.934249 (rank : 14)	θ value	1.00825e-67 (rank : 23)
Query Neighborhood Hits	105	Target Neighborhood Hits	54	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

RA54B_MOUSE
NC score	0.932576 (rank : 15)	θ value	1.36269e-64 (rank : 25)
Query Neighborhood Hits	105	Target Neighborhood Hits	59	Shared Neighborhood Hits	44
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

CHD9_HUMAN
NC score	0.931488 (rank : 16)	θ value	1.81628e-109 (rank : 17)
Query Neighborhood Hits	105	Target Neighborhood Hits	343	Shared Neighborhood Hits	46
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

RAD54_HUMAN
NC score	0.928701 (rank : 17)	θ value	2.32979e-56 (rank : 27)
Query Neighborhood Hits	105	Target Neighborhood Hits	51	Shared Neighborhood Hits	38
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

RAD54_MOUSE
NC score	0.928163 (rank : 18)	θ value	1.78386e-56 (rank : 26)
Query Neighborhood Hits	105	Target Neighborhood Hits	51	Shared Neighborhood Hits	38
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

CHD9_MOUSE
NC score	0.926936 (rank : 19)	θ value	1.39067e-109 (rank : 16)
Query Neighborhood Hits	105	Target Neighborhood Hits	427	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

INOC1_MOUSE
NC score	0.920806 (rank : 20)	θ value	1.5555e-68 (rank : 22)
Query Neighborhood Hits	105	Target Neighborhood Hits	178	Shared Neighborhood Hits	43
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

INOC1_HUMAN
NC score	0.920765 (rank : 21)	θ value	4.09345e-69 (rank : 21)
Query Neighborhood Hits	105	Target Neighborhood Hits	181	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

SMCA2_HUMAN
NC score	0.915459 (rank : 22)	θ value	1.58377e-121 (rank : 9)
Query Neighborhood Hits	105	Target Neighborhood Hits	503	Shared Neighborhood Hits	55
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SMCA4_HUMAN
NC score	0.904779 (rank : 23)	θ value	3.29472e-127 (rank : 5)
Query Neighborhood Hits	105	Target Neighborhood Hits	597	Shared Neighborhood Hits	58
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

CHD3_HUMAN
NC score	0.881097 (rank : 24)	θ value	1.34075e-120 (rank : 10)
Query Neighborhood Hits	105	Target Neighborhood Hits	397	Shared Neighborhood Hits	47
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD4_HUMAN
NC score	0.879050 (rank : 25)	θ value	4.03687e-117 (rank : 12)
Query Neighborhood Hits	105	Target Neighborhood Hits	365	Shared Neighborhood Hits	47
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD5_HUMAN
NC score	0.878886 (rank : 26)	θ value	3.30237e-119 (rank : 11)
Query Neighborhood Hits	105	Target Neighborhood Hits	349	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHD4_MOUSE
NC score	0.875545 (rank : 27)	θ value	4.03687e-117 (rank : 13)
Query Neighborhood Hits	105	Target Neighborhood Hits	408	Shared Neighborhood Hits	48
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

TTF2_HUMAN
NC score	0.861380 (rank : 28)	θ value	2.58786e-39 (rank : 30)
Query Neighborhood Hits	105	Target Neighborhood Hits	98	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

SMAL1_MOUSE
NC score	0.843082 (rank : 29)	θ value	9.54697e-26 (rank : 33)
Query Neighborhood Hits	105	Target Neighborhood Hits	157	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

SMAL1_HUMAN
NC score	0.835725 (rank : 30)	θ value	1.85889e-29 (rank : 32)
Query Neighborhood Hits	105	Target Neighborhood Hits	174	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

EP400_HUMAN
NC score	0.832034 (rank : 31)	θ value	1.04822e-48 (rank : 29)
Query Neighborhood Hits	105	Target Neighborhood Hits	556	Shared Neighborhood Hits	45
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EP400_MOUSE
NC score	0.825050 (rank : 32)	θ value	8.02596e-49 (rank : 28)
Query Neighborhood Hits	105	Target Neighborhood Hits	592	Shared Neighborhood Hits	48
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

TTF2_MOUSE
NC score	0.818727 (rank : 33)	θ value	9.52487e-34 (rank : 31)
Query Neighborhood Hits	105	Target Neighborhood Hits	364	Shared Neighborhood Hits	51
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

SMRA3_MOUSE
NC score	0.723678 (rank : 34)	θ value	1.74391e-19 (rank : 37)
Query Neighborhood Hits	105	Target Neighborhood Hits	267	Shared Neighborhood Hits	39
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

SMRA3_HUMAN
NC score	0.722258 (rank : 35)	θ value	3.51386e-20 (rank : 36)
Query Neighborhood Hits	105	Target Neighborhood Hits	265	Shared Neighborhood Hits	39
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

ATRX_MOUSE
NC score	0.694918 (rank : 36)	θ value	6.18819e-25 (rank : 34)
Query Neighborhood Hits	105	Target Neighborhood Hits	682	Shared Neighborhood Hits	51
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

ATRX_HUMAN
NC score	0.676145 (rank : 37)	θ value	1.80048e-24 (rank : 35)
Query Neighborhood Hits	105	Target Neighborhood Hits	842	Shared Neighborhood Hits	62
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

AIRE_MOUSE
NC score	0.101238 (rank : 38)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	105	Target Neighborhood Hits	196	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

AIRE_HUMAN
NC score	0.099499 (rank : 39)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	105	Target Neighborhood Hits	144	Shared Neighborhood Hits	8
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

PHF12_MOUSE
NC score	0.093620 (rank : 40)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	105	Target Neighborhood Hits	172	Shared Neighborhood Hits	9
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_HUMAN
NC score	0.093394 (rank : 41)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	105	Target Neighborhood Hits	174	Shared Neighborhood Hits	8
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

BPTF_HUMAN
NC score	0.091976 (rank : 42)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	105	Target Neighborhood Hits	786	Shared Neighborhood Hits	29
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

PF21B_MOUSE
NC score	0.089364 (rank : 43)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	105	Target Neighborhood Hits	278	Shared Neighborhood Hits	10
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PKCB1_HUMAN
NC score	0.089339 (rank : 44)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	105	Target Neighborhood Hits	488	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

PF21B_HUMAN
NC score	0.088271 (rank : 45)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	105	Target Neighborhood Hits	197	Shared Neighborhood Hits	7
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21A_MOUSE
NC score	0.086458 (rank : 46)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	105	Target Neighborhood Hits	285	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21A_HUMAN
NC score	0.085292 (rank : 47)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	105	Target Neighborhood Hits	303	Shared Neighborhood Hits	9
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

ZMY11_HUMAN
NC score	0.082841 (rank : 48)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	105	Target Neighborhood Hits	201	Shared Neighborhood Hits	16
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

CBX5_HUMAN
NC score	0.082517 (rank : 49)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	105	Target Neighborhood Hits	70	Shared Neighborhood Hits	12
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

ZMY11_MOUSE
NC score	0.080367 (rank : 50)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	105	Target Neighborhood Hits	198	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

BAZ1B_MOUSE
NC score	0.079380 (rank : 51)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	105	Target Neighborhood Hits	394	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

RSF1_HUMAN
NC score	0.076208 (rank : 52)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	105	Target Neighborhood Hits	539	Shared Neighborhood Hits	25
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SP110_HUMAN
NC score	0.075889 (rank : 53)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	105	Target Neighborhood Hits	141	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

BAZ1A_HUMAN
NC score	0.074139 (rank : 54)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	105	Target Neighborhood Hits	693	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

CBX5_MOUSE
NC score	0.073673 (rank : 55)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	105	Target Neighborhood Hits	67	Shared Neighborhood Hits	11
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

IWS1_MOUSE
NC score	0.072438 (rank : 56)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	105	Target Neighborhood Hits	1258	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TRI66_MOUSE
NC score	0.072423 (rank : 57)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	105	Target Neighborhood Hits	491	Shared Neighborhood Hits	21
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_HUMAN
NC score	0.072296 (rank : 58)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	105	Target Neighborhood Hits	479	Shared Neighborhood Hits	20
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

BAZ1B_HUMAN
NC score	0.072185 (rank : 59)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	105	Target Neighborhood Hits	701	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

TIF1A_MOUSE
NC score	0.071672 (rank : 60)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	105	Target Neighborhood Hits	307	Shared Neighborhood Hits	13
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1G_MOUSE
NC score	0.070172 (rank : 61)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	105	Target Neighborhood Hits	498	Shared Neighborhood Hits	16
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TGON2_HUMAN
NC score	0.070128 (rank : 62)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	105	Target Neighborhood Hits	1037	Shared Neighborhood Hits	28
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

PL10_MOUSE
NC score	0.068311 (rank : 63)	θ value	0.365318 (rank : 50)
Query Neighborhood Hits	105	Target Neighborhood Hits	120	Shared Neighborhood Hits	28
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

TIF1A_HUMAN
NC score	0.068183 (rank : 64)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	105	Target Neighborhood Hits	327	Shared Neighborhood Hits	11
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

CBX1_HUMAN
NC score	0.068168 (rank : 65)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	105	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
NC score	0.068168 (rank : 66)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	105	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

LY10_HUMAN
NC score	0.067804 (rank : 67)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	105	Target Neighborhood Hits	151	Shared Neighborhood Hits	11
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

DDX41_MOUSE
NC score	0.066164 (rank : 68)	θ value	0.365318 (rank : 49)
Query Neighborhood Hits	105	Target Neighborhood Hits	115	Shared Neighborhood Hits	29
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

NIPBL_HUMAN
NC score	0.065301 (rank : 69)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	105	Target Neighborhood Hits	1311	Shared Neighborhood Hits	44
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

LEO1_MOUSE
NC score	0.065117 (rank : 70)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	105	Target Neighborhood Hits	946	Shared Neighborhood Hits	37
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

NSD1_MOUSE
NC score	0.064297 (rank : 71)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	105	Target Neighborhood Hits	472	Shared Neighborhood Hits	16
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

IWS1_HUMAN
NC score	0.064236 (rank : 72)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	105	Target Neighborhood Hits	1241	Shared Neighborhood Hits	39
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

DDX3X_MOUSE
NC score	0.063710 (rank : 73)	θ value	0.813845 (rank : 57)
Query Neighborhood Hits	105	Target Neighborhood Hits	117	Shared Neighborhood Hits	28
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX3X_HUMAN
NC score	0.063518 (rank : 74)	θ value	0.813845 (rank : 56)
Query Neighborhood Hits	105	Target Neighborhood Hits	122	Shared Neighborhood Hits	28
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

CBX7_MOUSE
NC score	0.063204 (rank : 75)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	105	Target Neighborhood Hits	38	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VDS3	Gene names	Cbx7, D15Ertd417e
Domain Architecture
Description	Chromobox protein homolog 7.

CBX3_MOUSE
NC score	0.063044 (rank : 76)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	105	Target Neighborhood Hits	39	Shared Neighborhood Hits	10
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

LEO1_HUMAN
NC score	0.062951 (rank : 77)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	105	Target Neighborhood Hits	958	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

DDX41_HUMAN
NC score	0.062564 (rank : 78)	θ value	0.365318 (rank : 48)
Query Neighborhood Hits	105	Target Neighborhood Hits	111	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

TIF1G_HUMAN
NC score	0.062555 (rank : 79)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	105	Target Neighborhood Hits	410	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

NSD1_HUMAN
NC score	0.062091 (rank : 80)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	105	Target Neighborhood Hits	427	Shared Neighborhood Hits	13
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

CBX3_HUMAN
NC score	0.059894 (rank : 81)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	105	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

DDX3Y_HUMAN
NC score	0.059887 (rank : 82)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	105	Target Neighborhood Hits	121	Shared Neighborhood Hits	28
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

CBX7_HUMAN
NC score	0.059874 (rank : 83)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	105	Target Neighborhood Hits	48	Shared Neighborhood Hits	8
SwissProt Accessions	O95931, Q86T17	Gene names	CBX7
Domain Architecture
Description	Chromobox protein homolog 7.

FANCM_HUMAN
NC score	0.059842 (rank : 84)	θ value	0.0330416 (rank : 38)
Query Neighborhood Hits	105	Target Neighborhood Hits	210	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

NPBL_MOUSE
NC score	0.059133 (rank : 85)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	105	Target Neighborhood Hits	1041	Shared Neighborhood Hits	38
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

BAZ2B_HUMAN
NC score	0.058765 (rank : 86)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	105	Target Neighborhood Hits	803	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

MLL3_HUMAN
NC score	0.058706 (rank : 87)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	105	Target Neighborhood Hits	1644	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

TXND2_MOUSE
NC score	0.057490 (rank : 88)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	105	Target Neighborhood Hits	828	Shared Neighborhood Hits	36
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

DDX23_HUMAN
NC score	0.057095 (rank : 89)	θ value	0.21417 (rank : 46)
Query Neighborhood Hits	105	Target Neighborhood Hits	486	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

PB1_HUMAN
NC score	0.056438 (rank : 90)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	105	Target Neighborhood Hits	261	Shared Neighborhood Hits	5
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

DPF1_HUMAN
NC score	0.055954 (rank : 91)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	105	Target Neighborhood Hits	136	Shared Neighborhood Hits	5
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

TCAL5_HUMAN
NC score	0.055486 (rank : 92)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	105	Target Neighborhood Hits	806	Shared Neighborhood Hits	33
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

UHRF2_HUMAN
NC score	0.054744 (rank : 93)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	105	Target Neighborhood Hits	269	Shared Neighborhood Hits	9
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

RBBP6_MOUSE
NC score	0.054335 (rank : 94)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	105	Target Neighborhood Hits	1014	Shared Neighborhood Hits	35
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

BAZ2A_MOUSE
NC score	0.054116 (rank : 95)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	105	Target Neighborhood Hits	744	Shared Neighborhood Hits	27
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BAZ2A_HUMAN
NC score	0.054109 (rank : 96)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	105	Target Neighborhood Hits	780	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

RBBP6_HUMAN
NC score	0.053098 (rank : 97)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	105	Target Neighborhood Hits	1135	Shared Neighborhood Hits	38
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

PHF20_MOUSE
NC score	0.053034 (rank : 98)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	105	Target Neighborhood Hits	513	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PHF10_HUMAN
NC score	0.052324 (rank : 99)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	105	Target Neighborhood Hits	151	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

MLL3_MOUSE
NC score	0.051706 (rank : 100)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	105	Target Neighborhood Hits	1399	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PHF10_MOUSE
NC score	0.051377 (rank : 101)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	105	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

UHRF1_HUMAN
NC score	0.051227 (rank : 102)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	105	Target Neighborhood Hits	272	Shared Neighborhood Hits	9
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

BRD1_HUMAN
NC score	0.051070 (rank : 103)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	105	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

MLL2_HUMAN
NC score	0.050723 (rank : 104)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	105	Target Neighborhood Hits	1788	Shared Neighborhood Hits	39
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

UHRF2_MOUSE
NC score	0.050523 (rank : 105)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	105	Target Neighborhood Hits	275	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

CJ049_HUMAN
NC score	0.039816 (rank : 106)	θ value	0.279714 (rank : 47)
Query Neighborhood Hits	105	Target Neighborhood Hits	90	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WVF2	Gene names	C10orf49
Domain Architecture	No domain graphic available
Description	Protein C10orf49 precursor.

PCLO_MOUSE
NC score	0.039244 (rank : 107)	θ value	0.0961366 (rank : 43)
Query Neighborhood Hits	105	Target Neighborhood Hits	2275	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

TNNT2_HUMAN
NC score	0.038835 (rank : 108)	θ value	0.0736092 (rank : 42)
Query Neighborhood Hits	105	Target Neighborhood Hits	433	Shared Neighborhood Hits	21
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

DDX49_MOUSE
NC score	0.035118 (rank : 109)	θ value	0.0563607 (rank : 41)
Query Neighborhood Hits	105	Target Neighborhood Hits	119	Shared Neighborhood Hits	22
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

PSMD1_HUMAN
NC score	0.031230 (rank : 110)	θ value	0.163984 (rank : 44)
Query Neighborhood Hits	105	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	Q99460, Q53TI2, Q6GMU5, Q6P2P4, Q6PJM7, Q6PKG9, Q86VU1, Q8IV79	Gene names	PSMD1
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112).

PSMD1_MOUSE
NC score	0.031125 (rank : 111)	θ value	0.163984 (rank : 45)
Query Neighborhood Hits	105	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	Q3TXS7	Gene names	Psmd1
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1).

PCLO_HUMAN
NC score	0.030946 (rank : 112)	θ value	0.47712 (rank : 53)
Query Neighborhood Hits	105	Target Neighborhood Hits	2046	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

DDX49_HUMAN
NC score	0.029431 (rank : 113)	θ value	0.47712 (rank : 52)
Query Neighborhood Hits	105	Target Neighborhood Hits	223	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

BRD4_MOUSE
NC score	0.029309 (rank : 114)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	105	Target Neighborhood Hits	845	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

DDX48_MOUSE
NC score	0.029139 (rank : 115)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	105	Target Neighborhood Hits	102	Shared Neighborhood Hits	19
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX48_HUMAN
NC score	0.029136 (rank : 116)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	105	Target Neighborhood Hits	102	Shared Neighborhood Hits	19
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

TNNT2_MOUSE
NC score	0.027577 (rank : 117)	θ value	0.365318 (rank : 51)
Query Neighborhood Hits	105	Target Neighborhood Hits	395	Shared Neighborhood Hits	19
SwissProt Accessions	P50752, Q64360, Q64377	Gene names	Tnnt2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

BRD4_HUMAN
NC score	0.027504 (rank : 118)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	105	Target Neighborhood Hits	851	Shared Neighborhood Hits	30
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

SDPR_HUMAN
NC score	0.024323 (rank : 119)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	105	Target Neighborhood Hits	337	Shared Neighborhood Hits	25
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

CAF1A_MOUSE
NC score	0.024009 (rank : 120)	θ value	0.62314 (rank : 54)
Query Neighborhood Hits	105	Target Neighborhood Hits	736	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

LBN_MOUSE
NC score	0.021115 (rank : 121)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	105	Target Neighborhood Hits	310	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K1G2, Q8BRF3	Gene names	Evc2, Lbn
Domain Architecture	No domain graphic available
Description	Limbin.

TNNT3_HUMAN
NC score	0.019880 (rank : 122)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	105	Target Neighborhood Hits	327	Shared Neighborhood Hits	16
SwissProt Accessions	P45378, Q12975, Q12976, Q12977, Q12978, Q86TH6	Gene names	TNNT3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT) (Beta TnTF).

CAF1A_HUMAN
NC score	0.017850 (rank : 123)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	105	Target Neighborhood Hits	750	Shared Neighborhood Hits	29
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

GP179_HUMAN
NC score	0.017135 (rank : 124)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	105	Target Neighborhood Hits	372	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

POF1B_HUMAN
NC score	0.016836 (rank : 125)	θ value	0.0431538 (rank : 40)
Query Neighborhood Hits	105	Target Neighborhood Hits	494	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WVV4, Q5H9E9, Q5H9F0, Q8NG12, Q9H5Y2, Q9H738, Q9H744	Gene names	POF1B
Domain Architecture	No domain graphic available
Description	Protein POF1B (Premature ovarian failure protein 1B).

SYCC_MOUSE
NC score	0.016809 (rank : 126)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	105	Target Neighborhood Hits	63	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ER72, O88303, Q8BP81, Q8CAY7, Q8CCE3, Q8K0S4, Q9ER68	Gene names	Cars
Domain Architecture
Description	Cysteinyl-tRNA synthetase, cytoplasmic (EC 6.1.1.16) (Cysteine--tRNA ligase) (CysRS).

K1210_HUMAN
NC score	0.014685 (rank : 127)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	105	Target Neighborhood Hits	219	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

MYH11_HUMAN
NC score	0.014373 (rank : 128)	θ value	0.0330416 (rank : 39)
Query Neighborhood Hits	105	Target Neighborhood Hits	1806	Shared Neighborhood Hits	51
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

LMBL3_MOUSE
NC score	0.013829 (rank : 129)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	105	Target Neighborhood Hits	212	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BLB7, Q641L7, Q6ZPI2, Q8C0G4	Gene names	L3mbtl3
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein).

SETD2_HUMAN
NC score	0.013721 (rank : 130)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	105	Target Neighborhood Hits	412	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

LBN_HUMAN
NC score	0.013449 (rank : 131)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	105	Target Neighborhood Hits	308	Shared Neighborhood Hits	16
SwissProt Accessions	Q86UK5, Q86YT3, Q86YT4, Q8NG49	Gene names	EVC2, LBN
Domain Architecture	No domain graphic available
Description	Limbin.

KI21A_HUMAN
NC score	0.013090 (rank : 132)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	105	Target Neighborhood Hits	1543	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

SPTN5_HUMAN
NC score	0.012550 (rank : 133)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	105	Target Neighborhood Hits	674	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

ZN294_HUMAN
NC score	0.012351 (rank : 134)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	105	Target Neighborhood Hits	86	Shared Neighborhood Hits	4
SwissProt Accessions	O94822, Q9H8M4, Q9NUY5, Q9P0E9	Gene names	ZNF294, C21orf10, C21orf98, KIAA0714
Domain Architecture
Description	Zinc finger protein 294.

PEPL_MOUSE
NC score	0.012109 (rank : 135)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	105	Target Neighborhood Hits	1105	Shared Neighborhood Hits	36
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

ANR26_MOUSE
NC score	0.012070 (rank : 136)	θ value	0.813845 (rank : 55)
Query Neighborhood Hits	105	Target Neighborhood Hits	1554	Shared Neighborhood Hits	45
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

UBXD2_MOUSE
NC score	0.011598 (rank : 137)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	105	Target Neighborhood Hits	183	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VCH8, Q8BW17	Gene names	Ubxd2, Ubxdc1
Domain Architecture
Description	UBX domain-containing protein 2.

UB7I1_HUMAN
NC score	0.010692 (rank : 138)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	105	Target Neighborhood Hits	177	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

ANR12_HUMAN
NC score	0.010231 (rank : 139)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	105	Target Neighborhood Hits	1081	Shared Neighborhood Hits	32
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

IMMT_HUMAN
NC score	0.010217 (rank : 140)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	105	Target Neighborhood Hits	494	Shared Neighborhood Hits	25
SwissProt Accessions	Q16891, Q14539, Q15092, Q68D41, Q69HW5, Q6IBL0, Q7Z3X1, Q8TAJ5, Q9P0V2	Gene names	IMMT, HMP, PIG4
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin) (p87/89) (Proliferation-inducing gene 4 protein).

SYCC_HUMAN
NC score	0.009988 (rank : 141)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	105	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	P49589, Q53XI8, Q9HD24, Q9HD25	Gene names	CARS
Domain Architecture
Description	Cysteinyl-tRNA synthetase, cytoplasmic (EC 6.1.1.16) (Cysteine--tRNA ligase) (CysRS).

SH21B_MOUSE
NC score	0.009276 (rank : 142)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	105	Target Neighborhood Hits	101	Shared Neighborhood Hits	3
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

TRHY_HUMAN
NC score	0.009004 (rank : 143)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	105	Target Neighborhood Hits	1385	Shared Neighborhood Hits	35
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

FLIP1_MOUSE
NC score	0.008804 (rank : 144)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	105	Target Neighborhood Hits	1176	Shared Neighborhood Hits	37
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

CE290_HUMAN
NC score	0.008334 (rank : 145)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	105	Target Neighborhood Hits	1553	Shared Neighborhood Hits	42
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

WBP11_HUMAN
NC score	0.008112 (rank : 146)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	105	Target Neighborhood Hits	354	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

PER2_HUMAN
NC score	0.008014 (rank : 147)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	105	Target Neighborhood Hits	170	Shared Neighborhood Hits	7
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

CCHCR_MOUSE
NC score	0.007926 (rank : 148)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	105	Target Neighborhood Hits	932	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

STK10_HUMAN
NC score	0.007918 (rank : 149)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	105	Target Neighborhood Hits	1921	Shared Neighborhood Hits	46
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

NFM_MOUSE
NC score	0.007396 (rank : 150)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	105	Target Neighborhood Hits	1159	Shared Neighborhood Hits	34
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

SH3K1_MOUSE
NC score	0.007193 (rank : 151)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	105	Target Neighborhood Hits	332	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

CEP63_HUMAN
NC score	0.006199 (rank : 152)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	105	Target Neighborhood Hits	1005	Shared Neighborhood Hits	34
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

PLEC1_HUMAN
NC score	0.006165 (rank : 153)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	105	Target Neighborhood Hits	1326	Shared Neighborhood Hits	32
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

RADI_MOUSE
NC score	0.005753 (rank : 154)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	105	Target Neighborhood Hits	773	Shared Neighborhood Hits	25
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

MACOI_MOUSE
NC score	0.005697 (rank : 155)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	105	Target Neighborhood Hits	620	Shared Neighborhood Hits	29
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

FA47A_HUMAN
NC score	0.005526 (rank : 156)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	105	Target Neighborhood Hits	451	Shared Neighborhood Hits	11
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

BPAEA_HUMAN
NC score	0.004981 (rank : 157)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	105	Target Neighborhood Hits	1369	Shared Neighborhood Hits	30
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CEP55_HUMAN
NC score	0.004492 (rank : 158)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	105	Target Neighborhood Hits	504	Shared Neighborhood Hits	23
SwissProt Accessions	Q53EZ4, Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7	Gene names	CEP55, C10orf3, URCC6
Domain Architecture	No domain graphic available
Description	Centrosome protein 55 (Up-regulated in colon cancer 6).

ACAD9_HUMAN
NC score	0.004440 (rank : 159)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	105	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H845, Q8WXX3	Gene names	ACAD9
Domain Architecture
Description	Acyl-CoA dehydrogenase family member 9, mitochondrial precursor (EC 1.3.99.-) (ACAD-9).

PZRN4_HUMAN
NC score	0.003798 (rank : 160)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	105	Target Neighborhood Hits	438	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

MRCKB_MOUSE
NC score	0.003033 (rank : 161)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	105	Target Neighborhood Hits	2180	Shared Neighborhood Hits	43
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

TITIN_HUMAN
NC score	0.000959 (rank : 162)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	105	Target Neighborhood Hits	2923	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

GRK4_HUMAN
NC score	-0.002080 (rank : 163)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	105	Target Neighborhood Hits	822	Shared Neighborhood Hits	8
SwissProt Accessions	P32298, O00641, O00642, Q13293, Q13294, Q13295, Q14453, Q14725, Q15313, Q15314, Q15315, Q15316	Gene names	GRK4, GPRK2L, GPRK4
Domain Architecture
Description	G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1).

ZN628_HUMAN
NC score	-0.004360 (rank : 164)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	105	Target Neighborhood Hits	814	Shared Neighborhood Hits	3
SwissProt Accessions	Q5EBL2, Q86X34	Gene names	ZNF628
Domain Architecture	No domain graphic available
Description	Zinc finger protein 628.