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Network neighborhood for query Sequence : AIRE_HUMAN

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AIRE_HUMAN
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AIRE_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	144	Target Neighborhood Hits	144	Shared Neighborhood Hits	144
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	0 (rank : 2)	NC score	0.970581 (rank : 2)
Query Neighborhood Hits	144	Target Neighborhood Hits	196	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

CHD5_HUMAN
θ value	1.80466e-16 (rank : 3)	NC score	0.442051 (rank : 42)
Query Neighborhood Hits	144	Target Neighborhood Hits	349	Shared Neighborhood Hits	86
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

TRI66_MOUSE
θ value	4.91457e-14 (rank : 4)	NC score	0.607277 (rank : 8)
Query Neighborhood Hits	144	Target Neighborhood Hits	491	Shared Neighborhood Hits	82
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TIF1A_HUMAN
θ value	8.38298e-14 (rank : 5)	NC score	0.571838 (rank : 13)
Query Neighborhood Hits	144	Target Neighborhood Hits	327	Shared Neighborhood Hits	80
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TRI66_HUMAN
θ value	1.42992e-13 (rank : 6)	NC score	0.602839 (rank : 9)
Query Neighborhood Hits	144	Target Neighborhood Hits	479	Shared Neighborhood Hits	85
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TIF1A_MOUSE
θ value	2.43908e-13 (rank : 7)	NC score	0.576708 (rank : 12)
Query Neighborhood Hits	144	Target Neighborhood Hits	307	Shared Neighborhood Hits	83
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

CHD4_HUMAN
θ value	4.16044e-13 (rank : 8)	NC score	0.431604 (rank : 45)
Query Neighborhood Hits	144	Target Neighborhood Hits	365	Shared Neighborhood Hits	89
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	4.16044e-13 (rank : 9)	NC score	0.431266 (rank : 46)
Query Neighborhood Hits	144	Target Neighborhood Hits	408	Shared Neighborhood Hits	91
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

LY10_HUMAN
θ value	1.2105e-12 (rank : 10)	NC score	0.595718 (rank : 11)
Query Neighborhood Hits	144	Target Neighborhood Hits	151	Shared Neighborhood Hits	71
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

TIF1G_MOUSE
θ value	2.69671e-12 (rank : 11)	NC score	0.539800 (rank : 16)
Query Neighborhood Hits	144	Target Neighborhood Hits	498	Shared Neighborhood Hits	85
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

SP110_HUMAN
θ value	4.59992e-12 (rank : 12)	NC score	0.559120 (rank : 14)
Query Neighborhood Hits	144	Target Neighborhood Hits	141	Shared Neighborhood Hits	58
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

CHD3_HUMAN
θ value	7.84624e-12 (rank : 13)	NC score	0.425378 (rank : 51)
Query Neighborhood Hits	144	Target Neighborhood Hits	397	Shared Neighborhood Hits	92
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

TIF1G_HUMAN
θ value	7.84624e-12 (rank : 14)	NC score	0.538666 (rank : 17)
Query Neighborhood Hits	144	Target Neighborhood Hits	410	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

PF21A_HUMAN
θ value	1.02475e-11 (rank : 15)	NC score	0.691636 (rank : 4)
Query Neighborhood Hits	144	Target Neighborhood Hits	303	Shared Neighborhood Hits	85
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	1.02475e-11 (rank : 16)	NC score	0.698117 (rank : 3)
Query Neighborhood Hits	144	Target Neighborhood Hits	285	Shared Neighborhood Hits	80
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PHF12_HUMAN
θ value	2.28291e-11 (rank : 17)	NC score	0.660795 (rank : 5)
Query Neighborhood Hits	144	Target Neighborhood Hits	174	Shared Neighborhood Hits	82
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	2.28291e-11 (rank : 18)	NC score	0.660153 (rank : 6)
Query Neighborhood Hits	144	Target Neighborhood Hits	172	Shared Neighborhood Hits	81
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

BPTF_HUMAN
θ value	7.34386e-10 (rank : 19)	NC score	0.492233 (rank : 26)
Query Neighborhood Hits	144	Target Neighborhood Hits	786	Shared Neighborhood Hits	81
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BAZ1B_HUMAN
θ value	3.64472e-09 (rank : 20)	NC score	0.509176 (rank : 20)
Query Neighborhood Hits	144	Target Neighborhood Hits	701	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

PF21B_HUMAN
θ value	6.21693e-09 (rank : 21)	NC score	0.633220 (rank : 7)
Query Neighborhood Hits	144	Target Neighborhood Hits	197	Shared Neighborhood Hits	66
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

BAZ1B_MOUSE
θ value	1.38499e-08 (rank : 22)	NC score	0.543916 (rank : 15)
Query Neighborhood Hits	144	Target Neighborhood Hits	394	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

JAD1C_HUMAN
θ value	2.36244e-08 (rank : 23)	NC score	0.464331 (rank : 35)
Query Neighborhood Hits	144	Target Neighborhood Hits	187	Shared Neighborhood Hits	76
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

JAD1C_MOUSE
θ value	2.36244e-08 (rank : 24)	NC score	0.464866 (rank : 34)
Query Neighborhood Hits	144	Target Neighborhood Hits	164	Shared Neighborhood Hits	76
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

JAD1D_HUMAN
θ value	2.36244e-08 (rank : 25)	NC score	0.471362 (rank : 33)
Query Neighborhood Hits	144	Target Neighborhood Hits	147	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JAD1D_MOUSE
θ value	3.08544e-08 (rank : 26)	NC score	0.458222 (rank : 36)
Query Neighborhood Hits	144	Target Neighborhood Hits	228	Shared Neighborhood Hits	78
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

NSD1_HUMAN
θ value	3.08544e-08 (rank : 27)	NC score	0.445305 (rank : 40)
Query Neighborhood Hits	144	Target Neighborhood Hits	427	Shared Neighborhood Hits	86
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	3.08544e-08 (rank : 28)	NC score	0.449509 (rank : 38)
Query Neighborhood Hits	144	Target Neighborhood Hits	472	Shared Neighborhood Hits	88
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

TIF1B_MOUSE
θ value	5.26297e-08 (rank : 29)	NC score	0.516007 (rank : 19)
Query Neighborhood Hits	144	Target Neighborhood Hits	276	Shared Neighborhood Hits	68
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

BAZ2A_MOUSE
θ value	3.41135e-07 (rank : 30)	NC score	0.495283 (rank : 25)
Query Neighborhood Hits	144	Target Neighborhood Hits	744	Shared Neighborhood Hits	89
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

DPF1_MOUSE
θ value	3.41135e-07 (rank : 31)	NC score	0.496995 (rank : 23)
Query Neighborhood Hits	144	Target Neighborhood Hits	491	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

MLL3_HUMAN
θ value	5.81887e-07 (rank : 32)	NC score	0.378203 (rank : 57)
Query Neighborhood Hits	144	Target Neighborhood Hits	1644	Shared Neighborhood Hits	100
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
θ value	5.81887e-07 (rank : 33)	NC score	0.398600 (rank : 53)
Query Neighborhood Hits	144	Target Neighborhood Hits	1399	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PF21B_MOUSE
θ value	5.81887e-07 (rank : 34)	NC score	0.597847 (rank : 10)
Query Neighborhood Hits	144	Target Neighborhood Hits	278	Shared Neighborhood Hits	70
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

MYST3_HUMAN
θ value	9.92553e-07 (rank : 35)	NC score	0.425452 (rank : 50)
Query Neighborhood Hits	144	Target Neighborhood Hits	772	Shared Neighborhood Hits	89
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST3_MOUSE
θ value	9.92553e-07 (rank : 36)	NC score	0.428915 (rank : 49)
Query Neighborhood Hits	144	Target Neighborhood Hits	688	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

PHF14_MOUSE
θ value	9.92553e-07 (rank : 37)	NC score	0.443807 (rank : 41)
Query Neighborhood Hits	144	Target Neighborhood Hits	342	Shared Neighborhood Hits	81
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

JAD1A_HUMAN
θ value	1.29631e-06 (rank : 38)	NC score	0.454225 (rank : 37)
Query Neighborhood Hits	144	Target Neighborhood Hits	328	Shared Neighborhood Hits	81
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

BAZ2A_HUMAN
θ value	1.69304e-06 (rank : 39)	NC score	0.498679 (rank : 22)
Query Neighborhood Hits	144	Target Neighborhood Hits	780	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

PKCB1_HUMAN
θ value	1.69304e-06 (rank : 40)	NC score	0.496399 (rank : 24)
Query Neighborhood Hits	144	Target Neighborhood Hits	488	Shared Neighborhood Hits	85
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

DPF1_HUMAN
θ value	2.21117e-06 (rank : 41)	NC score	0.523787 (rank : 18)
Query Neighborhood Hits	144	Target Neighborhood Hits	136	Shared Neighborhood Hits	74
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

TIF1B_HUMAN
θ value	2.21117e-06 (rank : 42)	NC score	0.505027 (rank : 21)
Query Neighborhood Hits	144	Target Neighborhood Hits	312	Shared Neighborhood Hits	67
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

PHF14_HUMAN
θ value	2.88788e-06 (rank : 43)	NC score	0.434916 (rank : 44)
Query Neighborhood Hits	144	Target Neighborhood Hits	447	Shared Neighborhood Hits	79
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

BAZ1A_HUMAN
θ value	6.43352e-06 (rank : 44)	NC score	0.488327 (rank : 29)
Query Neighborhood Hits	144	Target Neighborhood Hits	693	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

MYST4_MOUSE
θ value	6.43352e-06 (rank : 45)	NC score	0.447627 (rank : 39)
Query Neighborhood Hits	144	Target Neighborhood Hits	416	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

MLL2_HUMAN
θ value	8.40245e-06 (rank : 46)	NC score	0.392573 (rank : 56)
Query Neighborhood Hits	144	Target Neighborhood Hits	1788	Shared Neighborhood Hits	101
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MYST4_HUMAN
θ value	8.40245e-06 (rank : 47)	NC score	0.429728 (rank : 48)
Query Neighborhood Hits	144	Target Neighborhood Hits	671	Shared Neighborhood Hits	88
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

REQU_HUMAN
θ value	8.40245e-06 (rank : 48)	NC score	0.490278 (rank : 27)
Query Neighborhood Hits	144	Target Neighborhood Hits	523	Shared Neighborhood Hits	76
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

REQU_MOUSE
θ value	8.40245e-06 (rank : 49)	NC score	0.489083 (rank : 28)
Query Neighborhood Hits	144	Target Neighborhood Hits	519	Shared Neighborhood Hits	76
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

UHRF2_MOUSE
θ value	1.87187e-05 (rank : 50)	NC score	0.394767 (rank : 55)
Query Neighborhood Hits	144	Target Neighborhood Hits	275	Shared Neighborhood Hits	70
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

BAZ2B_HUMAN
θ value	7.1131e-05 (rank : 51)	NC score	0.436604 (rank : 43)
Query Neighborhood Hits	144	Target Neighborhood Hits	803	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

RSF1_HUMAN
θ value	0.00020696 (rank : 52)	NC score	0.481094 (rank : 32)
Query Neighborhood Hits	144	Target Neighborhood Hits	539	Shared Neighborhood Hits	78
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

UHRF1_HUMAN
θ value	0.00035302 (rank : 53)	NC score	0.430615 (rank : 47)
Query Neighborhood Hits	144	Target Neighborhood Hits	272	Shared Neighborhood Hits	69
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF1_MOUSE
θ value	0.000461057 (rank : 54)	NC score	0.417133 (rank : 52)
Query Neighborhood Hits	144	Target Neighborhood Hits	278	Shared Neighborhood Hits	68
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

BRPF1_HUMAN
θ value	0.00175202 (rank : 55)	NC score	0.353224 (rank : 60)
Query Neighborhood Hits	144	Target Neighborhood Hits	259	Shared Neighborhood Hits	78
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

JADE2_HUMAN
θ value	0.00228821 (rank : 56)	NC score	0.327378 (rank : 66)
Query Neighborhood Hits	144	Target Neighborhood Hits	199	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

JADE2_MOUSE
θ value	0.00228821 (rank : 57)	NC score	0.311080 (rank : 68)
Query Neighborhood Hits	144	Target Neighborhood Hits	560	Shared Neighborhood Hits	80
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

UHRF2_HUMAN
θ value	0.00228821 (rank : 58)	NC score	0.394914 (rank : 54)
Query Neighborhood Hits	144	Target Neighborhood Hits	269	Shared Neighborhood Hits	71
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

JADE3_MOUSE
θ value	0.00509761 (rank : 59)	NC score	0.329471 (rank : 65)
Query Neighborhood Hits	144	Target Neighborhood Hits	174	Shared Neighborhood Hits	72
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

JADE3_HUMAN
θ value	0.00665767 (rank : 60)	NC score	0.325194 (rank : 67)
Query Neighborhood Hits	144	Target Neighborhood Hits	148	Shared Neighborhood Hits	73
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

BRD1_HUMAN
θ value	0.00869519 (rank : 61)	NC score	0.344718 (rank : 61)
Query Neighborhood Hits	144	Target Neighborhood Hits	188	Shared Neighborhood Hits	72
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

JADE1_HUMAN
θ value	0.00869519 (rank : 62)	NC score	0.330880 (rank : 63)
Query Neighborhood Hits	144	Target Neighborhood Hits	140	Shared Neighborhood Hits	71
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_MOUSE
θ value	0.00869519 (rank : 63)	NC score	0.330479 (rank : 64)
Query Neighborhood Hits	144	Target Neighborhood Hits	160	Shared Neighborhood Hits	71
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

PHF10_HUMAN
θ value	0.0193708 (rank : 64)	NC score	0.482996 (rank : 30)
Query Neighborhood Hits	144	Target Neighborhood Hits	151	Shared Neighborhood Hits	77
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
θ value	0.0252991 (rank : 65)	NC score	0.482074 (rank : 31)
Query Neighborhood Hits	144	Target Neighborhood Hits	131	Shared Neighborhood Hits	76
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PHF1_MOUSE
θ value	0.0252991 (rank : 66)	NC score	0.249918 (rank : 70)
Query Neighborhood Hits	144	Target Neighborhood Hits	116	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

SP100_HUMAN
θ value	0.0330416 (rank : 67)	NC score	0.115129 (rank : 123)
Query Neighborhood Hits	144	Target Neighborhood Hits	117	Shared Neighborhood Hits	13
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

ZMY11_HUMAN
θ value	0.0330416 (rank : 68)	NC score	0.355444 (rank : 59)
Query Neighborhood Hits	144	Target Neighborhood Hits	201	Shared Neighborhood Hits	61
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

BRPF3_HUMAN
θ value	0.0431538 (rank : 69)	NC score	0.339857 (rank : 62)
Query Neighborhood Hits	144	Target Neighborhood Hits	217	Shared Neighborhood Hits	70
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

PHF1_HUMAN
θ value	0.0431538 (rank : 70)	NC score	0.253243 (rank : 69)
Query Neighborhood Hits	144	Target Neighborhood Hits	117	Shared Neighborhood Hits	56
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

AMBN_HUMAN
θ value	0.0563607 (rank : 71)	NC score	0.057290 (rank : 235)
Query Neighborhood Hits	144	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NP70, Q9H2X1, Q9H4L1	Gene names	AMBN
Domain Architecture
Description	Ameloblastin precursor.

ATRX_HUMAN
θ value	0.0563607 (rank : 72)	NC score	0.162898 (rank : 81)
Query Neighborhood Hits	144	Target Neighborhood Hits	842	Shared Neighborhood Hits	47
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

ATRX_MOUSE
θ value	0.0563607 (rank : 73)	NC score	0.169822 (rank : 80)
Query Neighborhood Hits	144	Target Neighborhood Hits	682	Shared Neighborhood Hits	39
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

ZMY11_MOUSE
θ value	0.0736092 (rank : 74)	NC score	0.363308 (rank : 58)
Query Neighborhood Hits	144	Target Neighborhood Hits	198	Shared Neighborhood Hits	65
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

DOT1L_HUMAN
θ value	0.0961366 (rank : 75)	NC score	0.057380 (rank : 234)
Query Neighborhood Hits	144	Target Neighborhood Hits	660	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

SEPT9_HUMAN
θ value	0.0961366 (rank : 76)	NC score	0.038488 (rank : 263)
Query Neighborhood Hits	144	Target Neighborhood Hits	706	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

ING5_HUMAN
θ value	0.163984 (rank : 77)	NC score	0.159954 (rank : 85)
Query Neighborhood Hits	144	Target Neighborhood Hits	65	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WYH8, Q9BS30	Gene names	ING5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5 (p28ING5).

ING5_MOUSE
θ value	0.163984 (rank : 78)	NC score	0.155718 (rank : 88)
Query Neighborhood Hits	144	Target Neighborhood Hits	76	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D8Y8, Q3UL57, Q6P292, Q9CV64, Q9D9V8	Gene names	Ing5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5.

RGS3_MOUSE
θ value	0.21417 (rank : 79)	NC score	0.059545 (rank : 226)
Query Neighborhood Hits	144	Target Neighborhood Hits	1621	Shared Neighborhood Hits	43
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SLIK1_MOUSE
θ value	0.21417 (rank : 80)	NC score	0.014799 (rank : 279)
Query Neighborhood Hits	144	Target Neighborhood Hits	333	Shared Neighborhood Hits	7
SwissProt Accessions	Q810C1, Q9CXL0	Gene names	Slitrk1, Sltk1
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor.

ING3_HUMAN
θ value	0.279714 (rank : 81)	NC score	0.160648 (rank : 84)
Query Neighborhood Hits	144	Target Neighborhood Hits	178	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

AF10_HUMAN
θ value	0.365318 (rank : 82)	NC score	0.202782 (rank : 77)
Query Neighborhood Hits	144	Target Neighborhood Hits	198	Shared Neighborhood Hits	53
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

AF10_MOUSE
θ value	0.365318 (rank : 83)	NC score	0.203219 (rank : 76)
Query Neighborhood Hits	144	Target Neighborhood Hits	182	Shared Neighborhood Hits	55
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

AF17_HUMAN
θ value	0.365318 (rank : 84)	NC score	0.216695 (rank : 75)
Query Neighborhood Hits	144	Target Neighborhood Hits	230	Shared Neighborhood Hits	60
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

ING3_MOUSE
θ value	0.365318 (rank : 85)	NC score	0.144015 (rank : 102)
Query Neighborhood Hits	144	Target Neighborhood Hits	177	Shared Neighborhood Hits	42
SwissProt Accessions	Q8VEK6, Q99JS6, Q9ERB2	Gene names	Ing3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

XKR6_HUMAN
θ value	0.47712 (rank : 86)	NC score	0.021896 (rank : 271)
Query Neighborhood Hits	144	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q5GH73, Q8TBA0	Gene names	XKR6, C8orf21, C8orf7, XRG6
Domain Architecture	No domain graphic available
Description	XK-related protein 6.

EHMT2_MOUSE
θ value	0.813845 (rank : 87)	NC score	0.036403 (rank : 265)
Query Neighborhood Hits	144	Target Neighborhood Hits	750	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

LNP_MOUSE
θ value	0.813845 (rank : 88)	NC score	0.041188 (rank : 261)
Query Neighborhood Hits	144	Target Neighborhood Hits	83	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TQ95, Q69ZC5, Q6PAQ1, Q6PEN8	Gene names	Lnp, Kiaa1715, Uln
Domain Architecture	No domain graphic available
Description	Protein lunapark (Protein ulnaless).

RGS3_HUMAN
θ value	0.813845 (rank : 89)	NC score	0.052756 (rank : 243)
Query Neighborhood Hits	144	Target Neighborhood Hits	1375	Shared Neighborhood Hits	42
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

MLL4_HUMAN
θ value	1.06291 (rank : 90)	NC score	0.238746 (rank : 73)
Query Neighborhood Hits	144	Target Neighborhood Hits	722	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

PRAX_HUMAN
θ value	1.06291 (rank : 91)	NC score	0.034987 (rank : 266)
Query Neighborhood Hits	144	Target Neighborhood Hits	215	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

JHD1A_HUMAN
θ value	1.38821 (rank : 92)	NC score	0.055691 (rank : 237)
Query Neighborhood Hits	144	Target Neighborhood Hits	133	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

LAMA5_MOUSE
θ value	1.38821 (rank : 93)	NC score	0.008295 (rank : 289)
Query Neighborhood Hits	144	Target Neighborhood Hits	828	Shared Neighborhood Hits	13
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

PCLO_HUMAN
θ value	1.38821 (rank : 94)	NC score	0.061796 (rank : 214)
Query Neighborhood Hits	144	Target Neighborhood Hits	2046	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

IPR1_MOUSE
θ value	1.81305 (rank : 95)	NC score	0.146591 (rank : 98)
Query Neighborhood Hits	144	Target Neighborhood Hits	65	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BVK9, Q3UCV7, Q80V00	Gene names	Ipr1, Ifi75
Domain Architecture	No domain graphic available
Description	Intracellular pathogen resistance protein 1.

KLF16_MOUSE
θ value	1.81305 (rank : 96)	NC score	-0.001831 (rank : 303)
Query Neighborhood Hits	144	Target Neighborhood Hits	719	Shared Neighborhood Hits	10
SwissProt Accessions	P58334, Q3U3Y4, Q8C8S2	Gene names	Klf16, Bteb4, Drrf
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 16 (Transcription factor BTEB4) (Basic transcription element-binding protein 4) (BTE-binding protein 4) (Dopamine receptor-regulating factor).

SHC1_HUMAN
θ value	1.81305 (rank : 97)	NC score	0.016457 (rank : 273)
Query Neighborhood Hits	144	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SLIK1_HUMAN
θ value	1.81305 (rank : 98)	NC score	0.011943 (rank : 281)
Query Neighborhood Hits	144	Target Neighborhood Hits	297	Shared Neighborhood Hits	5
SwissProt Accessions	Q96PX8, Q5U5I6, Q96SF9	Gene names	SLITRK1, KIAA1910, LRRC12
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor (Leucine-rich repeat-containing protein 12).

NACAM_MOUSE
θ value	2.36792 (rank : 99)	NC score	0.062164 (rank : 212)
Query Neighborhood Hits	144	Target Neighborhood Hits	1866	Shared Neighborhood Hits	59
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NFH_MOUSE
θ value	2.36792 (rank : 100)	NC score	0.040404 (rank : 262)
Query Neighborhood Hits	144	Target Neighborhood Hits	2247	Shared Neighborhood Hits	59
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RAI14_HUMAN
θ value	2.36792 (rank : 101)	NC score	0.002846 (rank : 299)
Query Neighborhood Hits	144	Target Neighborhood Hits	1367	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

BSN_MOUSE
θ value	3.0926 (rank : 102)	NC score	0.048694 (rank : 260)
Query Neighborhood Hits	144	Target Neighborhood Hits	2057	Shared Neighborhood Hits	47
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MMRN1_HUMAN
θ value	3.0926 (rank : 103)	NC score	0.009942 (rank : 283)
Query Neighborhood Hits	144	Target Neighborhood Hits	636	Shared Neighborhood Hits	8
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

MTF2_HUMAN
θ value	3.0926 (rank : 104)	NC score	0.243853 (rank : 71)
Query Neighborhood Hits	144	Target Neighborhood Hits	119	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MTF2_MOUSE
θ value	3.0926 (rank : 105)	NC score	0.243348 (rank : 72)
Query Neighborhood Hits	144	Target Neighborhood Hits	126	Shared Neighborhood Hits	70
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

RPGF1_HUMAN
θ value	3.0926 (rank : 106)	NC score	0.014947 (rank : 277)
Query Neighborhood Hits	144	Target Neighborhood Hits	262	Shared Neighborhood Hits	8
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

SHC1_MOUSE
θ value	3.0926 (rank : 107)	NC score	0.015296 (rank : 276)
Query Neighborhood Hits	144	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

TCF19_HUMAN
θ value	3.0926 (rank : 108)	NC score	0.110489 (rank : 126)
Query Neighborhood Hits	144	Target Neighborhood Hits	124	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y242, Q13176, Q15967, Q5SQ89, Q5STD6, Q5STF5, Q9BUM2, Q9UBH7	Gene names	TCF19, SC1
Domain Architecture
Description	Transcription factor 19 (Transcription factor SC1).

WN10A_MOUSE
θ value	3.0926 (rank : 109)	NC score	0.009900 (rank : 284)
Query Neighborhood Hits	144	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	P70701	Gene names	Wnt10a
Domain Architecture
Description	Protein Wnt-10a precursor.

WNT2B_HUMAN
θ value	3.0926 (rank : 110)	NC score	0.009891 (rank : 285)
Query Neighborhood Hits	144	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q93097, O14903, Q9HDC1, Q9HDC2	Gene names	WNT2B, WNT13
Domain Architecture
Description	Protein Wnt-2b precursor (Wnt-13).

WNT2B_MOUSE
θ value	3.0926 (rank : 111)	NC score	0.009882 (rank : 286)
Query Neighborhood Hits	144	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	O70283, O88530	Gene names	Wnt2b, Wnt13
Domain Architecture
Description	Protein Wnt-2b precursor (Wnt-13).

CEND1_HUMAN
θ value	4.03905 (rank : 112)	NC score	0.005808 (rank : 293)
Query Neighborhood Hits	144	Target Neighborhood Hits	284	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

DEAF1_HUMAN
θ value	4.03905 (rank : 113)	NC score	0.094879 (rank : 155)
Query Neighborhood Hits	144	Target Neighborhood Hits	67	Shared Neighborhood Hits	14
SwissProt Accessions	O75398, O15152, O75399, O75510, O75511, O75512, O75513, Q9UET1	Gene names	DEAF1, SPN, ZMYND5
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR) (Suppressin) (Zinc finger MYND domain-containing protein 5).

DEAF1_MOUSE
θ value	4.03905 (rank : 114)	NC score	0.097877 (rank : 149)
Query Neighborhood Hits	144	Target Neighborhood Hits	70	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z1T5	Gene names	Deaf1
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR).

NFX1_HUMAN
θ value	4.03905 (rank : 115)	NC score	0.062056 (rank : 213)
Query Neighborhood Hits	144	Target Neighborhood Hits	405	Shared Neighborhood Hits	34
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

PIDD_HUMAN
θ value	4.03905 (rank : 116)	NC score	0.006007 (rank : 292)
Query Neighborhood Hits	144	Target Neighborhood Hits	271	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HB75, Q59FD1, Q59H10, Q59HC7, Q7Z4P8, Q8NC89, Q8NDL2, Q96C25, Q9NRE6	Gene names	LRDD, PIDD
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and death domain-containing protein (p53-induced protein with a death domain).

REG3G_HUMAN
θ value	4.03905 (rank : 117)	NC score	0.008125 (rank : 290)
Query Neighborhood Hits	144	Target Neighborhood Hits	86	Shared Neighborhood Hits	2
SwissProt Accessions	Q6UW15, Q6FH18	Gene names	REG3G, PAP1B
Domain Architecture	No domain graphic available
Description	Regenerating islet-derived protein 3 gamma precursor (Reg III-gamma) (Pancreatitis-associated protein 1B) (PAP IB).

ZN516_MOUSE
θ value	4.03905 (rank : 118)	NC score	0.002870 (rank : 298)
Query Neighborhood Hits	144	Target Neighborhood Hits	1197	Shared Neighborhood Hits	19
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

ZN606_HUMAN
θ value	4.03905 (rank : 119)	NC score	-0.003128 (rank : 306)
Query Neighborhood Hits	144	Target Neighborhood Hits	749	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WXB4, Q8NE04, Q96JH5	Gene names	ZNF606, KIAA1852, ZNF328
Domain Architecture
Description	Zinc finger protein 606 (Zinc finger protein 328).

E2F4_HUMAN
θ value	5.27518 (rank : 120)	NC score	0.016481 (rank : 272)
Query Neighborhood Hits	144	Target Neighborhood Hits	188	Shared Neighborhood Hits	11
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

JHD1A_MOUSE
θ value	5.27518 (rank : 121)	NC score	0.050963 (rank : 253)
Query Neighborhood Hits	144	Target Neighborhood Hits	134	Shared Neighborhood Hits	24
SwissProt Accessions	P59997, Q3U1M5, Q3UR56, Q3V3Q1, Q69ZT4	Gene names	Fbxl11, Jhdm1a, Kiaa1004
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11).

LAMA1_MOUSE
θ value	5.27518 (rank : 122)	NC score	0.004029 (rank : 296)
Query Neighborhood Hits	144	Target Neighborhood Hits	838	Shared Neighborhood Hits	10
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LNP_HUMAN
θ value	5.27518 (rank : 123)	NC score	0.031247 (rank : 268)
Query Neighborhood Hits	144	Target Neighborhood Hits	62	Shared Neighborhood Hits	5
SwissProt Accessions	Q9C0E8, Q2M2V8, Q2YD99, Q658W8, Q8N5V9, Q96MS5	Gene names	LNP, KIAA1715
Domain Architecture	No domain graphic available
Description	Protein lunapark.

NCA11_MOUSE
θ value	5.27518 (rank : 124)	NC score	0.007314 (rank : 291)
Query Neighborhood Hits	144	Target Neighborhood Hits	661	Shared Neighborhood Hits	17
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

PCSK5_MOUSE
θ value	5.27518 (rank : 125)	NC score	0.022446 (rank : 270)
Query Neighborhood Hits	144	Target Neighborhood Hits	613	Shared Neighborhood Hits	17
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

PLCB1_HUMAN
θ value	5.27518 (rank : 126)	NC score	0.012770 (rank : 280)
Query Neighborhood Hits	144	Target Neighborhood Hits	614	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

SYAC_HUMAN
θ value	5.27518 (rank : 127)	NC score	0.016291 (rank : 274)
Query Neighborhood Hits	144	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	P49588, Q53GV7, Q96FA0	Gene names	AARS
Domain Architecture
Description	Alanyl-tRNA synthetase, cytoplasmic (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS) (NY-REN-42 antigen).

SYAC_MOUSE
θ value	5.27518 (rank : 128)	NC score	0.016152 (rank : 275)
Query Neighborhood Hits	144	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGQ7, Q8BXR0	Gene names	Aars
Domain Architecture
Description	Alanyl-tRNA synthetase, cytoplasmic (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS).

ZFP38_HUMAN
θ value	5.27518 (rank : 129)	NC score	-0.002760 (rank : 305)
Query Neighborhood Hits	144	Target Neighborhood Hits	766	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y5A6, Q9H0B5	Gene names	ZNF38, ZFP38, ZSCAN21
Domain Architecture
Description	Zinc finger protein 38 homolog (Zfp-38) (Zinc finger and SCAN domain- containing protein 21) (NY-REN-21 antigen).

AMFR_MOUSE
θ value	6.88961 (rank : 130)	NC score	0.008967 (rank : 288)
Query Neighborhood Hits	144	Target Neighborhood Hits	208	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

FYV1_MOUSE
θ value	6.88961 (rank : 131)	NC score	0.009722 (rank : 287)
Query Neighborhood Hits	144	Target Neighborhood Hits	191	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

GLI3_HUMAN
θ value	6.88961 (rank : 132)	NC score	-0.001043 (rank : 302)
Query Neighborhood Hits	144	Target Neighborhood Hits	871	Shared Neighborhood Hits	18
SwissProt Accessions	P10071, O75219, Q9UDT5, Q9UJ39	Gene names	GLI3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

SP100_MOUSE
θ value	6.88961 (rank : 133)	NC score	0.095790 (rank : 154)
Query Neighborhood Hits	144	Target Neighborhood Hits	32	Shared Neighborhood Hits	9
SwissProt Accessions	O35892, O35897, O88392, O88395	Gene names	Sp100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein).

SYNP2_MOUSE
θ value	6.88961 (rank : 134)	NC score	0.014848 (rank : 278)
Query Neighborhood Hits	144	Target Neighborhood Hits	252	Shared Neighborhood Hits	11
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

BAT2_HUMAN
θ value	8.99809 (rank : 135)	NC score	0.036995 (rank : 264)
Query Neighborhood Hits	144	Target Neighborhood Hits	931	Shared Neighborhood Hits	29
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CIC_HUMAN
θ value	8.99809 (rank : 136)	NC score	0.028052 (rank : 269)
Query Neighborhood Hits	144	Target Neighborhood Hits	992	Shared Neighborhood Hits	30
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

EGFL7_MOUSE
θ value	8.99809 (rank : 137)	NC score	0.003040 (rank : 297)
Query Neighborhood Hits	144	Target Neighborhood Hits	287	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

K2C7_HUMAN
θ value	8.99809 (rank : 138)	NC score	0.000324 (rank : 301)
Query Neighborhood Hits	144	Target Neighborhood Hits	369	Shared Neighborhood Hits	4
SwissProt Accessions	P08729, Q92676, Q9BUD8, Q9Y3R7	Gene names	KRT7, SCL
Domain Architecture
Description	Keratin, type II cytoskeletal 7 (Cytokeratin-7) (CK-7) (Keratin-7) (K7) (Sarcolectin).

LAMB2_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.004456 (rank : 294)
Query Neighborhood Hits	144	Target Neighborhood Hits	692	Shared Neighborhood Hits	9
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

MAGA5_HUMAN
θ value	8.99809 (rank : 140)	NC score	0.011797 (rank : 282)
Query Neighborhood Hits	144	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	P43359	Gene names	MAGEA5, MAGE5
Domain Architecture
Description	Melanoma-associated antigen 5 (MAGE-5 antigen).

NKX24_HUMAN
θ value	8.99809 (rank : 141)	NC score	0.004399 (rank : 295)
Query Neighborhood Hits	144	Target Neighborhood Hits	366	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H2Z4	Gene names	NKX2-4, NKX2D
Domain Architecture
Description	Homeobox protein Nkx-2.4 (Homeobox protein NKX2.4) (Homeobox protein NK-2 homolog D).

PRAX_MOUSE
θ value	8.99809 (rank : 142)	NC score	0.034050 (rank : 267)
Query Neighborhood Hits	144	Target Neighborhood Hits	199	Shared Neighborhood Hits	17
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

SALL3_HUMAN
θ value	8.99809 (rank : 143)	NC score	0.001906 (rank : 300)
Query Neighborhood Hits	144	Target Neighborhood Hits	1066	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

ZSCA1_HUMAN
θ value	8.99809 (rank : 144)	NC score	-0.002727 (rank : 304)
Query Neighborhood Hits	144	Target Neighborhood Hits	724	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NBB4, Q6WLH8, Q86WS8	Gene names	ZSCAN1
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 1.

ARI1A_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.060968 (rank : 223)
Query Neighborhood Hits	144	Target Neighborhood Hits	787	Shared Neighborhood Hits	28
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

ARI1B_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.051101 (rank : 252)
Query Neighborhood Hits	144	Target Neighborhood Hits	567	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ARI3A_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.063724 (rank : 206)
Query Neighborhood Hits	144	Target Neighborhood Hits	80	Shared Neighborhood Hits	10
SwissProt Accessions	Q99856, Q8IZA7	Gene names	ARID3A, DRIL1, DRX, E2FBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 3A (ARID domain- containing protein 3A) (B-cell regulator of IgH transcription) (Bright) (E2F-binding protein 1).

ARI3A_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.061736 (rank : 215)
Query Neighborhood Hits	144	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	Q62431	Gene names	Arid3a, Dri1, Dril1
Domain Architecture
Description	AT-rich interactive domain-containing protein 3A (ARID domain- containing protein 3A) (Dead ringer-like protein 1) (B-cell regulator of IgH transcription) (Bright).

ARI4A_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.052151 (rank : 246)
Query Neighborhood Hits	144	Target Neighborhood Hits	434	Shared Neighborhood Hits	16
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

ARI5B_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.066398 (rank : 197)
Query Neighborhood Hits	144	Target Neighborhood Hits	328	Shared Neighborhood Hits	26
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

ATAD2_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.057758 (rank : 231)
Query Neighborhood Hits	144	Target Neighborhood Hits	322	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

ATAD2_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.054925 (rank : 240)
Query Neighborhood Hits	144	Target Neighborhood Hits	167	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

BRD2_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.155352 (rank : 90)
Query Neighborhood Hits	144	Target Neighborhood Hits	242	Shared Neighborhood Hits	27
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

BRD3_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.140378 (rank : 108)
Query Neighborhood Hits	144	Target Neighborhood Hits	369	Shared Neighborhood Hits	27
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BRD3_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.140610 (rank : 107)
Query Neighborhood Hits	144	Target Neighborhood Hits	402	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

BRD4_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.144960 (rank : 100)
Query Neighborhood Hits	144	Target Neighborhood Hits	851	Shared Neighborhood Hits	43
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

BRD4_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.145855 (rank : 99)
Query Neighborhood Hits	144	Target Neighborhood Hits	845	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BRD7_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.113053 (rank : 125)
Query Neighborhood Hits	144	Target Neighborhood Hits	94	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

BRD7_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.110364 (rank : 127)
Query Neighborhood Hits	144	Target Neighborhood Hits	141	Shared Neighborhood Hits	21
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

BRD8_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.140949 (rank : 106)
Query Neighborhood Hits	144	Target Neighborhood Hits	292	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

BRD8_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.135407 (rank : 112)
Query Neighborhood Hits	144	Target Neighborhood Hits	422	Shared Neighborhood Hits	36
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

BRD9_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.113488 (rank : 124)
Query Neighborhood Hits	144	Target Neighborhood Hits	56	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H8M2, Q2XUS1, Q6UWU9, Q8IUS4, Q9H5Q5, Q9H7R9	Gene names	BRD9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS- 40.8).

BRD9_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.120276 (rank : 119)
Query Neighborhood Hits	144	Target Neighborhood Hits	84	Shared Neighborhood Hits	19
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

BRDT_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.135948 (rank : 109)
Query Neighborhood Hits	144	Target Neighborhood Hits	280	Shared Neighborhood Hits	25
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

BRDT_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.135539 (rank : 110)
Query Neighborhood Hits	144	Target Neighborhood Hits	243	Shared Neighborhood Hits	24
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

BRWD1_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.073373 (rank : 191)
Query Neighborhood Hits	144	Target Neighborhood Hits	448	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

BRWD1_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.076343 (rank : 187)
Query Neighborhood Hits	144	Target Neighborhood Hits	478	Shared Neighborhood Hits	25
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

BTAF1_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.085126 (rank : 176)
Query Neighborhood Hits	144	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

CBP_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.120588 (rank : 118)
Query Neighborhood Hits	144	Target Neighborhood Hits	941	Shared Neighborhood Hits	42
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CBP_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.126395 (rank : 116)
Query Neighborhood Hits	144	Target Neighborhood Hits	1051	Shared Neighborhood Hits	52
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CECR2_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.174237 (rank : 79)
Query Neighborhood Hits	144	Target Neighborhood Hits	543	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CHD1_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.106856 (rank : 133)
Query Neighborhood Hits	144	Target Neighborhood Hits	337	Shared Neighborhood Hits	12
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.106070 (rank : 134)
Query Neighborhood Hits	144	Target Neighborhood Hits	266	Shared Neighborhood Hits	10
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD2_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.108091 (rank : 130)
Query Neighborhood Hits	144	Target Neighborhood Hits	360	Shared Neighborhood Hits	14
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CHD6_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.108881 (rank : 129)
Query Neighborhood Hits	144	Target Neighborhood Hits	342	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CHD8_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.103818 (rank : 138)
Query Neighborhood Hits	144	Target Neighborhood Hits	235	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CHD9_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.105033 (rank : 136)
Query Neighborhood Hits	144	Target Neighborhood Hits	343	Shared Neighborhood Hits	13
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CHD9_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.103561 (rank : 139)
Query Neighborhood Hits	144	Target Neighborhood Hits	427	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

CXCC1_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.101278 (rank : 141)
Query Neighborhood Hits	144	Target Neighborhood Hits	143	Shared Neighborhood Hits	43
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

CXCC1_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.096325 (rank : 153)
Query Neighborhood Hits	144	Target Neighborhood Hits	124	Shared Neighborhood Hits	43
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

DIDO1_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.083499 (rank : 178)
Query Neighborhood Hits	144	Target Neighborhood Hits	960	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

DNM3L_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.065610 (rank : 198)
Query Neighborhood Hits	144	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	Q9CWR8	Gene names	Dnmt3l
Domain Architecture	No domain graphic available
Description	DNA (cytosine-5)-methyltransferase 3-like.

DPF3_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.120002 (rank : 121)
Query Neighborhood Hits	144	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q92784, Q9H7Y5	Gene names	DPF3, CERD4
Domain Architecture	No domain graphic available
Description	Zinc-finger protein DPF3 (cer-d4).

DPF3_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.144666 (rank : 101)
Query Neighborhood Hits	144	Target Neighborhood Hits	327	Shared Neighborhood Hits	14
SwissProt Accessions	P58269	Gene names	Dpf3, Cerd4
Domain Architecture	No domain graphic available
Description	Zinc-finger protein Dpf3 (cer-d4).

EP300_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.127424 (rank : 115)
Query Neighborhood Hits	144	Target Neighborhood Hits	821	Shared Neighborhood Hits	47
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

EP400_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.094078 (rank : 158)
Query Neighborhood Hits	144	Target Neighborhood Hits	556	Shared Neighborhood Hits	30
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EP400_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.094674 (rank : 156)
Query Neighborhood Hits	144	Target Neighborhood Hits	592	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

ERCC6_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.099792 (rank : 143)
Query Neighborhood Hits	144	Target Neighborhood Hits	247	Shared Neighborhood Hits	11
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

EZH1_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.063694 (rank : 207)
Query Neighborhood Hits	144	Target Neighborhood Hits	121	Shared Neighborhood Hits	9
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.063774 (rank : 205)
Query Neighborhood Hits	144	Target Neighborhood Hits	126	Shared Neighborhood Hits	10
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH2_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.064092 (rank : 203)
Query Neighborhood Hits	144	Target Neighborhood Hits	84	Shared Neighborhood Hits	7
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH2_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.063445 (rank : 209)
Query Neighborhood Hits	144	Target Neighborhood Hits	86	Shared Neighborhood Hits	7
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

GCNL2_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.155556 (rank : 89)
Query Neighborhood Hits	144	Target Neighborhood Hits	159	Shared Neighborhood Hits	24
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

GCNL2_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.151867 (rank : 95)
Query Neighborhood Hits	144	Target Neighborhood Hits	146	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

GSCR1_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.053608 (rank : 241)
Query Neighborhood Hits	144	Target Neighborhood Hits	674	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HRX_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.223915 (rank : 74)
Query Neighborhood Hits	144	Target Neighborhood Hits	825	Shared Neighborhood Hits	77
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

ING1_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.105927 (rank : 135)
Query Neighborhood Hits	144	Target Neighborhood Hits	65	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UK53, O00532, O43658, Q9H007, Q9HD98, Q9HD99, Q9NS83, Q9P0U6, Q9UBC6, Q9UIJ1, Q9UIJ2, Q9UIJ3, Q9UIJ4, Q9UK52	Gene names	ING1
Domain Architecture
Description	Inhibitor of growth protein 1.

ING1_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.107287 (rank : 132)
Query Neighborhood Hits	144	Target Neighborhood Hits	71	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QXV3, Q9QUP8, Q9QXV4, Q9QZX3	Gene names	Ing1
Domain Architecture
Description	Inhibitor of growth protein 1.

ING2_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.117199 (rank : 122)
Query Neighborhood Hits	144	Target Neighborhood Hits	101	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H160, O95698	Gene names	ING2, ING1L
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein) (ING1Lp) (p32).

ING2_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.120020 (rank : 120)
Query Neighborhood Hits	144	Target Neighborhood Hits	102	Shared Neighborhood Hits	34
SwissProt Accessions	Q9ESK4, Q80VI5, Q8BGU8	Gene names	Ing2, Ing1l
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein).

ING4_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.104576 (rank : 137)
Query Neighborhood Hits	144	Target Neighborhood Hits	82	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UNL4, Q96E15, Q9H3J0	Gene names	ING4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

ING4_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.103226 (rank : 140)
Query Neighborhood Hits	144	Target Neighborhood Hits	93	Shared Neighborhood Hits	35
SwissProt Accessions	Q8C0D7, Q8C1S7, Q8K3Q5, Q8K3Q6, Q8K3Q7, Q9D7F9	Gene names	Ing4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

INOC1_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.088773 (rank : 172)
Query Neighborhood Hits	144	Target Neighborhood Hits	181	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

INOC1_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.088863 (rank : 171)
Query Neighborhood Hits	144	Target Neighborhood Hits	178	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

IWS1_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.064972 (rank : 199)
Query Neighborhood Hits	144	Target Neighborhood Hits	1241	Shared Neighborhood Hits	39
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.073066 (rank : 192)
Query Neighborhood Hits	144	Target Neighborhood Hits	1258	Shared Neighborhood Hits	40
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JARD2_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.100077 (rank : 142)
Query Neighborhood Hits	144	Target Neighborhood Hits	119	Shared Neighborhood Hits	8
SwissProt Accessions	Q92833, Q5U5L5	Gene names	JARID2, JMJ
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

JARD2_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.097840 (rank : 150)
Query Neighborhood Hits	144	Target Neighborhood Hits	169	Shared Neighborhood Hits	11
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

JHD3A_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.154080 (rank : 93)
Query Neighborhood Hits	144	Target Neighborhood Hits	78	Shared Neighborhood Hits	30
SwissProt Accessions	O75164, Q5VVB1	Gene names	JMJD2A, JHDM3A, JMJD2, KIAA0677
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3A_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.158759 (rank : 86)
Query Neighborhood Hits	144	Target Neighborhood Hits	85	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BW72, Q3UKM5, Q3UM81, Q3UWV2, Q6ZQ72, Q8K137	Gene names	Jmjd2a, Jhdm3a, Jmjd2, Kiaa0677
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3B_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.151293 (rank : 97)
Query Neighborhood Hits	144	Target Neighborhood Hits	128	Shared Neighborhood Hits	31
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3B_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.153383 (rank : 94)
Query Neighborhood Hits	144	Target Neighborhood Hits	152	Shared Neighborhood Hits	34
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3C_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.151784 (rank : 96)
Query Neighborhood Hits	144	Target Neighborhood Hits	91	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

JHD3C_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.154274 (rank : 91)
Query Neighborhood Hits	144	Target Neighborhood Hits	84	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

JHD3D_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.080491 (rank : 180)
Query Neighborhood Hits	144	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	Q6B0I6, Q9NT41, Q9NW76	Gene names	JMJD2D, JHDM3D
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

JHD3D_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.081565 (rank : 179)
Query Neighborhood Hits	144	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	Q3U2K5, Q2M1G7, Q8BI19	Gene names	Jmjd2d, Jhdm3d
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

MDC1_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.058395 (rank : 230)
Query Neighborhood Hits	144	Target Neighborhood Hits	1446	Shared Neighborhood Hits	45
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MDC1_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.050606 (rank : 255)
Query Neighborhood Hits	144	Target Neighborhood Hits	998	Shared Neighborhood Hits	47
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MUC7_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.055655 (rank : 238)
Query Neighborhood Hits	144	Target Neighborhood Hits	538	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MYST1_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.091425 (rank : 169)
Query Neighborhood Hits	144	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H7Z6, Q659G0, Q7LC17, Q8IY59, Q8WYB4, Q8WZ14, Q9HAC5, Q9NR35	Gene names	MYST1, MOF
Domain Architecture	No domain graphic available
Description	Probable histone acetyltransferase MYST1 (EC 2.3.1.48) (MYST protein 1) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (hMOF).

MYST1_MOUSE
θ value	θ > 10 (rank : 221)	NC score	0.091359 (rank : 170)
Query Neighborhood Hits	144	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D1P2, Q3UIY0, Q8BJ69, Q8BJ76, Q8CI73	Gene names	Myst1, Mof
Domain Architecture	No domain graphic available
Description	Probable histone acetyltransferase MYST1 (EC 2.3.1.48) (MYST protein 1) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1).

MYST2_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.092428 (rank : 159)
Query Neighborhood Hits	144	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	O95251	Gene names	MYST2, HBO1, HBOa
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

MYST2_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.092392 (rank : 160)
Query Neighborhood Hits	144	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q5SVQ0, Q5SVQ1, Q5SVQ2, Q5SVQ3, Q5SVQ7, Q6PGC6, Q80Y65	Gene names	Myst2, Hbo1
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

NIPBL_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.061436 (rank : 218)
Query Neighborhood Hits	144	Target Neighborhood Hits	1311	Shared Neighborhood Hits	41
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.050790 (rank : 254)
Query Neighborhood Hits	144	Target Neighborhood Hits	1041	Shared Neighborhood Hits	36
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PB1_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.121052 (rank : 117)
Query Neighborhood Hits	144	Target Neighborhood Hits	261	Shared Neighborhood Hits	23
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

PCAF_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.156472 (rank : 87)
Query Neighborhood Hits	144	Target Neighborhood Hits	68	Shared Neighborhood Hits	18
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

PHF11_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.069464 (rank : 195)
Query Neighborhood Hits	144	Target Neighborhood Hits	42	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

PHF20_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.074181 (rank : 189)
Query Neighborhood Hits	144	Target Neighborhood Hits	394	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

PHF20_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.077990 (rank : 184)
Query Neighborhood Hits	144	Target Neighborhood Hits	513	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PHF22_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.154160 (rank : 92)
Query Neighborhood Hits	144	Target Neighborhood Hits	121	Shared Neighborhood Hits	39
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

PHF22_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.161051 (rank : 83)
Query Neighborhood Hits	144	Target Neighborhood Hits	89	Shared Neighborhood Hits	41
SwissProt Accessions	Q9D168, Q3U2Q5, Q921U2	Gene names	Ints12, Phf22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

PHF2_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.051438 (rank : 251)
Query Neighborhood Hits	144	Target Neighborhood Hits	208	Shared Neighborhood Hits	34
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PHF2_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.051739 (rank : 248)
Query Neighborhood Hits	144	Target Neighborhood Hits	241	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PHF3_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.053168 (rank : 242)
Query Neighborhood Hits	144	Target Neighborhood Hits	419	Shared Neighborhood Hits	28
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

PHF6_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.061715 (rank : 216)
Query Neighborhood Hits	144	Target Neighborhood Hits	37	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

PHF6_MOUSE
θ value	θ > 10 (rank : 237)	NC score	0.057583 (rank : 232)
Query Neighborhood Hits	144	Target Neighborhood Hits	39	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

PHF7_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.085811 (rank : 175)
Query Neighborhood Hits	144	Target Neighborhood Hits	71	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PHF7_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.079003 (rank : 181)
Query Neighborhood Hits	144	Target Neighborhood Hits	65	Shared Neighborhood Hits	29
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PML_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.109615 (rank : 128)
Query Neighborhood Hits	144	Target Neighborhood Hits	248	Shared Neighborhood Hits	18
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

PML_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.107884 (rank : 131)
Query Neighborhood Hits	144	Target Neighborhood Hits	246	Shared Neighborhood Hits	13
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

RA54B_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.091968 (rank : 167)
Query Neighborhood Hits	144	Target Neighborhood Hits	54	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

RA54B_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.091871 (rank : 168)
Query Neighborhood Hits	144	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

RAD54_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.094091 (rank : 157)
Query Neighborhood Hits	144	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

RAD54_MOUSE
θ value	θ > 10 (rank : 245)	NC score	0.092353 (rank : 161)
Query Neighborhood Hits	144	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

RAI1_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.057190 (rank : 236)
Query Neighborhood Hits	144	Target Neighborhood Hits	360	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RAI1_MOUSE
θ value	θ > 10 (rank : 247)	NC score	0.061331 (rank : 219)
Query Neighborhood Hits	144	Target Neighborhood Hits	344	Shared Neighborhood Hits	31
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

S100R_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.092057 (rank : 166)
Query Neighborhood Hits	144	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q99388	Gene names	D1Lub1, Sp100-rs
Domain Architecture
Description	Putative Sp100-related protein.

SET1A_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.099176 (rank : 146)
Query Neighborhood Hits	144	Target Neighborhood Hits	690	Shared Neighborhood Hits	28
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SETB2_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.061443 (rank : 217)
Query Neighborhood Hits	144	Target Neighborhood Hits	62	Shared Neighborhood Hits	11
SwissProt Accessions	Q96T68, Q86UD6, Q96AI6	Gene names	SETDB2, CLLD8
Domain Architecture
Description	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein).

SETD2_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.085882 (rank : 174)
Query Neighborhood Hits	144	Target Neighborhood Hits	412	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SETD8_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.058454 (rank : 229)
Query Neighborhood Hits	144	Target Neighborhood Hits	114	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

SETD8_MOUSE
θ value	θ > 10 (rank : 253)	NC score	0.059699 (rank : 225)
Query Neighborhood Hits	144	Target Neighborhood Hits	131	Shared Neighborhood Hits	10
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

SMAL1_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.084911 (rank : 177)
Query Neighborhood Hits	144	Target Neighborhood Hits	174	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

SMAL1_MOUSE
θ value	θ > 10 (rank : 255)	NC score	0.087058 (rank : 173)
Query Neighborhood Hits	144	Target Neighborhood Hits	157	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

SMCA1_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.099499 (rank : 144)
Query Neighborhood Hits	144	Target Neighborhood Hits	105	Shared Neighborhood Hits	8
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMCA1_MOUSE
θ value	θ > 10 (rank : 257)	NC score	0.099356 (rank : 145)
Query Neighborhood Hits	144	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

SMCA2_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.143638 (rank : 103)
Query Neighborhood Hits	144	Target Neighborhood Hits	503	Shared Neighborhood Hits	35
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SMCA4_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.142577 (rank : 104)
Query Neighborhood Hits	144	Target Neighborhood Hits	597	Shared Neighborhood Hits	37
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SMCA5_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.099038 (rank : 148)
Query Neighborhood Hits	144	Target Neighborhood Hits	76	Shared Neighborhood Hits	7
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

SMCA5_MOUSE
θ value	θ > 10 (rank : 261)	NC score	0.099098 (rank : 147)
Query Neighborhood Hits	144	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

SMRA3_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.074181 (rank : 190)
Query Neighborhood Hits	144	Target Neighborhood Hits	265	Shared Neighborhood Hits	13
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

SMRA3_MOUSE
θ value	θ > 10 (rank : 263)	NC score	0.074504 (rank : 188)
Query Neighborhood Hits	144	Target Neighborhood Hits	267	Shared Neighborhood Hits	12
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

SMRCD_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.092111 (rank : 165)
Query Neighborhood Hits	144	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

SMRCD_MOUSE
θ value	θ > 10 (rank : 265)	NC score	0.092124 (rank : 164)
Query Neighborhood Hits	144	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

SON_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.057455 (rank : 233)
Query Neighborhood Hits	144	Target Neighborhood Hits	1568	Shared Neighborhood Hits	50
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SRRM1_MOUSE
θ value	θ > 10 (rank : 267)	NC score	0.050591 (rank : 256)
Query Neighborhood Hits	144	Target Neighborhood Hits	966	Shared Neighborhood Hits	35
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SUV91_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.061263 (rank : 220)
Query Neighborhood Hits	144	Target Neighborhood Hits	63	Shared Neighborhood Hits	8
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

SUV91_MOUSE
θ value	θ > 10 (rank : 269)	NC score	0.058900 (rank : 228)
Query Neighborhood Hits	144	Target Neighborhood Hits	69	Shared Neighborhood Hits	7
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

SUV92_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.064312 (rank : 202)
Query Neighborhood Hits	144	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV92_MOUSE
θ value	θ > 10 (rank : 271)	NC score	0.062416 (rank : 211)
Query Neighborhood Hits	144	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

TAF1L_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.134742 (rank : 113)
Query Neighborhood Hits	144	Target Neighborhood Hits	144	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZX4	Gene names	TAF1L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID 210 kDa subunit (TBP-associated factor 210 kDa) (TAF(II)210) (TBP-associated factor 1-like).

TAF1_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.141347 (rank : 105)
Query Neighborhood Hits	144	Target Neighborhood Hits	136	Shared Neighborhood Hits	22
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

TAF3_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.178556 (rank : 78)
Query Neighborhood Hits	144	Target Neighborhood Hits	568	Shared Neighborhood Hits	68
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TAF3_MOUSE
θ value	θ > 10 (rank : 275)	NC score	0.161114 (rank : 82)
Query Neighborhood Hits	144	Target Neighborhood Hits	463	Shared Neighborhood Hits	61
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TCF20_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.052047 (rank : 247)
Query Neighborhood Hits	144	Target Neighborhood Hits	323	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

TCF20_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.052414 (rank : 245)
Query Neighborhood Hits	144	Target Neighborhood Hits	396	Shared Neighborhood Hits	29
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

TGON2_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.051622 (rank : 250)
Query Neighborhood Hits	144	Target Neighborhood Hits	1037	Shared Neighborhood Hits	36
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TIP60_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.092211 (rank : 162)
Query Neighborhood Hits	144	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q92993, O95624, Q13430, Q6GSE8, Q9BWK7	Gene names	HTATIP, TIP60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60) (HIV-1 Tat interactive protein) (cPLA(2)-interacting protein).

TIP60_MOUSE
θ value	θ > 10 (rank : 280)	NC score	0.092204 (rank : 163)
Query Neighborhood Hits	144	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

TP53B_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.051667 (rank : 249)
Query Neighborhood Hits	144	Target Neighborhood Hits	644	Shared Neighborhood Hits	28
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TRI29_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.052755 (rank : 244)
Query Neighborhood Hits	144	Target Neighborhood Hits	273	Shared Neighborhood Hits	11
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI36_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.064350 (rank : 201)
Query Neighborhood Hits	144	Target Neighborhood Hits	282	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRI36_MOUSE
θ value	θ > 10 (rank : 284)	NC score	0.061167 (rank : 221)
Query Neighborhood Hits	144	Target Neighborhood Hits	266	Shared Neighborhood Hits	17
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRI37_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.050398 (rank : 257)
Query Neighborhood Hits	144	Target Neighborhood Hits	307	Shared Neighborhood Hits	12
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	θ > 10 (rank : 286)	NC score	0.050331 (rank : 258)
Query Neighborhood Hits	144	Target Neighborhood Hits	316	Shared Neighborhood Hits	12
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI42_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.069335 (rank : 196)
Query Neighborhood Hits	144	Target Neighborhood Hits	283	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI42_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.072178 (rank : 193)
Query Neighborhood Hits	144	Target Neighborhood Hits	316	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI45_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.135423 (rank : 111)
Query Neighborhood Hits	144	Target Neighborhood Hits	155	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI45_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.134129 (rank : 114)
Query Neighborhood Hits	144	Target Neighborhood Hits	155	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

TRI46_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.064883 (rank : 200)
Query Neighborhood Hits	144	Target Neighborhood Hits	291	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.063635 (rank : 208)
Query Neighborhood Hits	144	Target Neighborhood Hits	287	Shared Neighborhood Hits	15
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI55_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.050093 (rank : 259)
Query Neighborhood Hits	144	Target Neighborhood Hits	292	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI56_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.096834 (rank : 152)
Query Neighborhood Hits	144	Target Neighborhood Hits	339	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI56_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.097655 (rank : 151)
Query Neighborhood Hits	144	Target Neighborhood Hits	255	Shared Neighborhood Hits	13
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI63_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.063335 (rank : 210)
Query Neighborhood Hits	144	Target Neighborhood Hits	298	Shared Neighborhood Hits	14
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI63_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.055097 (rank : 239)
Query Neighborhood Hits	144	Target Neighborhood Hits	240	Shared Neighborhood Hits	13
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRIM1_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.060655 (rank : 224)
Query Neighborhood Hits	144	Target Neighborhood Hits	345	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.061028 (rank : 222)
Query Neighborhood Hits	144	Target Neighborhood Hits	361	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRIM2_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.078941 (rank : 182)
Query Neighborhood Hits	144	Target Neighborhood Hits	330	Shared Neighborhood Hits	14
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.078854 (rank : 183)
Query Neighborhood Hits	144	Target Neighborhood Hits	331	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRIM3_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.077223 (rank : 186)
Query Neighborhood Hits	144	Target Neighborhood Hits	357	Shared Neighborhood Hits	16
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM3_MOUSE
θ value	θ > 10 (rank : 303)	NC score	0.077821 (rank : 185)
Query Neighborhood Hits	144	Target Neighborhood Hits	351	Shared Neighborhood Hits	15
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TTF2_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.064091 (rank : 204)
Query Neighborhood Hits	144	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

TTF2_MOUSE
θ value	θ > 10 (rank : 305)	NC score	0.071073 (rank : 194)
Query Neighborhood Hits	144	Target Neighborhood Hits	364	Shared Neighborhood Hits	15
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

TXND2_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.059461 (rank : 227)
Query Neighborhood Hits	144	Target Neighborhood Hits	793	Shared Neighborhood Hits	35
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

Hits sorted by NC score

AIRE_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	144	Target Neighborhood Hits	144	Shared Neighborhood Hits	144
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
NC score	0.970581 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	144	Target Neighborhood Hits	196	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

PF21A_MOUSE
NC score	0.698117 (rank : 3)	θ value	1.02475e-11 (rank : 16)
Query Neighborhood Hits	144	Target Neighborhood Hits	285	Shared Neighborhood Hits	80
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21A_HUMAN
NC score	0.691636 (rank : 4)	θ value	1.02475e-11 (rank : 15)
Query Neighborhood Hits	144	Target Neighborhood Hits	303	Shared Neighborhood Hits	85
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PHF12_HUMAN
NC score	0.660795 (rank : 5)	θ value	2.28291e-11 (rank : 17)
Query Neighborhood Hits	144	Target Neighborhood Hits	174	Shared Neighborhood Hits	82
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
NC score	0.660153 (rank : 6)	θ value	2.28291e-11 (rank : 18)
Query Neighborhood Hits	144	Target Neighborhood Hits	172	Shared Neighborhood Hits	81
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PF21B_HUMAN
NC score	0.633220 (rank : 7)	θ value	6.21693e-09 (rank : 21)
Query Neighborhood Hits	144	Target Neighborhood Hits	197	Shared Neighborhood Hits	66
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

TRI66_MOUSE
NC score	0.607277 (rank : 8)	θ value	4.91457e-14 (rank : 4)
Query Neighborhood Hits	144	Target Neighborhood Hits	491	Shared Neighborhood Hits	82
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_HUMAN
NC score	0.602839 (rank : 9)	θ value	1.42992e-13 (rank : 6)
Query Neighborhood Hits	144	Target Neighborhood Hits	479	Shared Neighborhood Hits	85
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

PF21B_MOUSE
NC score	0.597847 (rank : 10)	θ value	5.81887e-07 (rank : 34)
Query Neighborhood Hits	144	Target Neighborhood Hits	278	Shared Neighborhood Hits	70
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

LY10_HUMAN
NC score	0.595718 (rank : 11)	θ value	1.2105e-12 (rank : 10)
Query Neighborhood Hits	144	Target Neighborhood Hits	151	Shared Neighborhood Hits	71
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

TIF1A_MOUSE
NC score	0.576708 (rank : 12)	θ value	2.43908e-13 (rank : 7)
Query Neighborhood Hits	144	Target Neighborhood Hits	307	Shared Neighborhood Hits	83
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1A_HUMAN
NC score	0.571838 (rank : 13)	θ value	8.38298e-14 (rank : 5)
Query Neighborhood Hits	144	Target Neighborhood Hits	327	Shared Neighborhood Hits	80
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

SP110_HUMAN
NC score	0.559120 (rank : 14)	θ value	4.59992e-12 (rank : 12)
Query Neighborhood Hits	144	Target Neighborhood Hits	141	Shared Neighborhood Hits	58
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

BAZ1B_MOUSE
NC score	0.543916 (rank : 15)	θ value	1.38499e-08 (rank : 22)
Query Neighborhood Hits	144	Target Neighborhood Hits	394	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

TIF1G_MOUSE
NC score	0.539800 (rank : 16)	θ value	2.69671e-12 (rank : 11)
Query Neighborhood Hits	144	Target Neighborhood Hits	498	Shared Neighborhood Hits	85
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TIF1G_HUMAN
NC score	0.538666 (rank : 17)	θ value	7.84624e-12 (rank : 14)
Query Neighborhood Hits	144	Target Neighborhood Hits	410	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

DPF1_HUMAN
NC score	0.523787 (rank : 18)	θ value	2.21117e-06 (rank : 41)
Query Neighborhood Hits	144	Target Neighborhood Hits	136	Shared Neighborhood Hits	74
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

TIF1B_MOUSE
NC score	0.516007 (rank : 19)	θ value	5.26297e-08 (rank : 29)
Query Neighborhood Hits	144	Target Neighborhood Hits	276	Shared Neighborhood Hits	68
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

BAZ1B_HUMAN
NC score	0.509176 (rank : 20)	θ value	3.64472e-09 (rank : 20)
Query Neighborhood Hits	144	Target Neighborhood Hits	701	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

TIF1B_HUMAN
NC score	0.505027 (rank : 21)	θ value	2.21117e-06 (rank : 42)
Query Neighborhood Hits	144	Target Neighborhood Hits	312	Shared Neighborhood Hits	67
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

BAZ2A_HUMAN
NC score	0.498679 (rank : 22)	θ value	1.69304e-06 (rank : 39)
Query Neighborhood Hits	144	Target Neighborhood Hits	780	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

DPF1_MOUSE
NC score	0.496995 (rank : 23)	θ value	3.41135e-07 (rank : 31)
Query Neighborhood Hits	144	Target Neighborhood Hits	491	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

PKCB1_HUMAN
NC score	0.496399 (rank : 24)	θ value	1.69304e-06 (rank : 40)
Query Neighborhood Hits	144	Target Neighborhood Hits	488	Shared Neighborhood Hits	85
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

BAZ2A_MOUSE
NC score	0.495283 (rank : 25)	θ value	3.41135e-07 (rank : 30)
Query Neighborhood Hits	144	Target Neighborhood Hits	744	Shared Neighborhood Hits	89
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BPTF_HUMAN
NC score	0.492233 (rank : 26)	θ value	7.34386e-10 (rank : 19)
Query Neighborhood Hits	144	Target Neighborhood Hits	786	Shared Neighborhood Hits	81
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

REQU_HUMAN
NC score	0.490278 (rank : 27)	θ value	8.40245e-06 (rank : 48)
Query Neighborhood Hits	144	Target Neighborhood Hits	523	Shared Neighborhood Hits	76
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

REQU_MOUSE
NC score	0.489083 (rank : 28)	θ value	8.40245e-06 (rank : 49)
Query Neighborhood Hits	144	Target Neighborhood Hits	519	Shared Neighborhood Hits	76
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

BAZ1A_HUMAN
NC score	0.488327 (rank : 29)	θ value	6.43352e-06 (rank : 44)
Query Neighborhood Hits	144	Target Neighborhood Hits	693	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

PHF10_HUMAN
NC score	0.482996 (rank : 30)	θ value	0.0193708 (rank : 64)
Query Neighborhood Hits	144	Target Neighborhood Hits	151	Shared Neighborhood Hits	77
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
NC score	0.482074 (rank : 31)	θ value	0.0252991 (rank : 65)
Query Neighborhood Hits	144	Target Neighborhood Hits	131	Shared Neighborhood Hits	76
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

RSF1_HUMAN
NC score	0.481094 (rank : 32)	θ value	0.00020696 (rank : 52)
Query Neighborhood Hits	144	Target Neighborhood Hits	539	Shared Neighborhood Hits	78
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

JAD1D_HUMAN
NC score	0.471362 (rank : 33)	θ value	2.36244e-08 (rank : 25)
Query Neighborhood Hits	144	Target Neighborhood Hits	147	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JAD1C_MOUSE
NC score	0.464866 (rank : 34)	θ value	2.36244e-08 (rank : 24)
Query Neighborhood Hits	144	Target Neighborhood Hits	164	Shared Neighborhood Hits	76
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

JAD1C_HUMAN
NC score	0.464331 (rank : 35)	θ value	2.36244e-08 (rank : 23)
Query Neighborhood Hits	144	Target Neighborhood Hits	187	Shared Neighborhood Hits	76
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

JAD1D_MOUSE
NC score	0.458222 (rank : 36)	θ value	3.08544e-08 (rank : 26)
Query Neighborhood Hits	144	Target Neighborhood Hits	228	Shared Neighborhood Hits	78
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JAD1A_HUMAN
NC score	0.454225 (rank : 37)	θ value	1.29631e-06 (rank : 38)
Query Neighborhood Hits	144	Target Neighborhood Hits	328	Shared Neighborhood Hits	81
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

NSD1_MOUSE
NC score	0.449509 (rank : 38)	θ value	3.08544e-08 (rank : 28)
Query Neighborhood Hits	144	Target Neighborhood Hits	472	Shared Neighborhood Hits	88
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

MYST4_MOUSE
NC score	0.447627 (rank : 39)	θ value	6.43352e-06 (rank : 45)
Query Neighborhood Hits	144	Target Neighborhood Hits	416	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

NSD1_HUMAN
NC score	0.445305 (rank : 40)	θ value	3.08544e-08 (rank : 27)
Query Neighborhood Hits	144	Target Neighborhood Hits	427	Shared Neighborhood Hits	86
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

PHF14_MOUSE
NC score	0.443807 (rank : 41)	θ value	9.92553e-07 (rank : 37)
Query Neighborhood Hits	144	Target Neighborhood Hits	342	Shared Neighborhood Hits	81
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

CHD5_HUMAN
NC score	0.442051 (rank : 42)	θ value	1.80466e-16 (rank : 3)
Query Neighborhood Hits	144	Target Neighborhood Hits	349	Shared Neighborhood Hits	86
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

BAZ2B_HUMAN
NC score	0.436604 (rank : 43)	θ value	7.1131e-05 (rank : 51)
Query Neighborhood Hits	144	Target Neighborhood Hits	803	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

PHF14_HUMAN
NC score	0.434916 (rank : 44)	θ value	2.88788e-06 (rank : 43)
Query Neighborhood Hits	144	Target Neighborhood Hits	447	Shared Neighborhood Hits	79
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

CHD4_HUMAN
NC score	0.431604 (rank : 45)	θ value	4.16044e-13 (rank : 8)
Query Neighborhood Hits	144	Target Neighborhood Hits	365	Shared Neighborhood Hits	89
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
NC score	0.431266 (rank : 46)	θ value	4.16044e-13 (rank : 9)
Query Neighborhood Hits	144	Target Neighborhood Hits	408	Shared Neighborhood Hits	91
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

UHRF1_HUMAN
NC score	0.430615 (rank : 47)	θ value	0.00035302 (rank : 53)
Query Neighborhood Hits	144	Target Neighborhood Hits	272	Shared Neighborhood Hits	69
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

MYST4_HUMAN
NC score	0.429728 (rank : 48)	θ value	8.40245e-06 (rank : 47)
Query Neighborhood Hits	144	Target Neighborhood Hits	671	Shared Neighborhood Hits	88
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MYST3_MOUSE
NC score	0.428915 (rank : 49)	θ value	9.92553e-07 (rank : 36)
Query Neighborhood Hits	144	Target Neighborhood Hits	688	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

MYST3_HUMAN
NC score	0.425452 (rank : 50)	θ value	9.92553e-07 (rank : 35)
Query Neighborhood Hits	144	Target Neighborhood Hits	772	Shared Neighborhood Hits	89
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

CHD3_HUMAN
NC score	0.425378 (rank : 51)	θ value	7.84624e-12 (rank : 13)
Query Neighborhood Hits	144	Target Neighborhood Hits	397	Shared Neighborhood Hits	92
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

UHRF1_MOUSE
NC score	0.417133 (rank : 52)	θ value	0.000461057 (rank : 54)
Query Neighborhood Hits	144	Target Neighborhood Hits	278	Shared Neighborhood Hits	68
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

MLL3_MOUSE
NC score	0.398600 (rank : 53)	θ value	5.81887e-07 (rank : 33)
Query Neighborhood Hits	144	Target Neighborhood Hits	1399	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

UHRF2_HUMAN
NC score	0.394914 (rank : 54)	θ value	0.00228821 (rank : 58)
Query Neighborhood Hits	144	Target Neighborhood Hits	269	Shared Neighborhood Hits	71
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
NC score	0.394767 (rank : 55)	θ value	1.87187e-05 (rank : 50)
Query Neighborhood Hits	144	Target Neighborhood Hits	275	Shared Neighborhood Hits	70
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

MLL2_HUMAN
NC score	0.392573 (rank : 56)	θ value	8.40245e-06 (rank : 46)
Query Neighborhood Hits	144	Target Neighborhood Hits	1788	Shared Neighborhood Hits	101
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL3_HUMAN
NC score	0.378203 (rank : 57)	θ value	5.81887e-07 (rank : 32)
Query Neighborhood Hits	144	Target Neighborhood Hits	1644	Shared Neighborhood Hits	100
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

ZMY11_MOUSE
NC score	0.363308 (rank : 58)	θ value	0.0736092 (rank : 74)
Query Neighborhood Hits	144	Target Neighborhood Hits	198	Shared Neighborhood Hits	65
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

ZMY11_HUMAN
NC score	0.355444 (rank : 59)	θ value	0.0330416 (rank : 68)
Query Neighborhood Hits	144	Target Neighborhood Hits	201	Shared Neighborhood Hits	61
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

BRPF1_HUMAN
NC score	0.353224 (rank : 60)	θ value	0.00175202 (rank : 55)
Query Neighborhood Hits	144	Target Neighborhood Hits	259	Shared Neighborhood Hits	78
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

BRD1_HUMAN
NC score	0.344718 (rank : 61)	θ value	0.00869519 (rank : 61)
Query Neighborhood Hits	144	Target Neighborhood Hits	188	Shared Neighborhood Hits	72
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

BRPF3_HUMAN
NC score	0.339857 (rank : 62)	θ value	0.0431538 (rank : 69)
Query Neighborhood Hits	144	Target Neighborhood Hits	217	Shared Neighborhood Hits	70
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

JADE1_HUMAN
NC score	0.330880 (rank : 63)	θ value	0.00869519 (rank : 62)
Query Neighborhood Hits	144	Target Neighborhood Hits	140	Shared Neighborhood Hits	71
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_MOUSE
NC score	0.330479 (rank : 64)	θ value	0.00869519 (rank : 63)
Query Neighborhood Hits	144	Target Neighborhood Hits	160	Shared Neighborhood Hits	71
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE3_MOUSE
NC score	0.329471 (rank : 65)	θ value	0.00509761 (rank : 59)
Query Neighborhood Hits	144	Target Neighborhood Hits	174	Shared Neighborhood Hits	72
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

JADE2_HUMAN
NC score	0.327378 (rank : 66)	θ value	0.00228821 (rank : 56)
Query Neighborhood Hits	144	Target Neighborhood Hits	199	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

JADE3_HUMAN
NC score	0.325194 (rank : 67)	θ value	0.00665767 (rank : 60)
Query Neighborhood Hits	144	Target Neighborhood Hits	148	Shared Neighborhood Hits	73
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

JADE2_MOUSE
NC score	0.311080 (rank : 68)	θ value	0.00228821 (rank : 57)
Query Neighborhood Hits	144	Target Neighborhood Hits	560	Shared Neighborhood Hits	80
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

PHF1_HUMAN
NC score	0.253243 (rank : 69)	θ value	0.0431538 (rank : 70)
Query Neighborhood Hits	144	Target Neighborhood Hits	117	Shared Neighborhood Hits	56
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PHF1_MOUSE
NC score	0.249918 (rank : 70)	θ value	0.0252991 (rank : 66)
Query Neighborhood Hits	144	Target Neighborhood Hits	116	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

MTF2_HUMAN
NC score	0.243853 (rank : 71)	θ value	3.0926 (rank : 104)
Query Neighborhood Hits	144	Target Neighborhood Hits	119	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MTF2_MOUSE
NC score	0.243348 (rank : 72)	θ value	3.0926 (rank : 105)
Query Neighborhood Hits	144	Target Neighborhood Hits	126	Shared Neighborhood Hits	70
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MLL4_HUMAN
NC score	0.238746 (rank : 73)	θ value	1.06291 (rank : 90)
Query Neighborhood Hits	144	Target Neighborhood Hits	722	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

HRX_HUMAN
NC score	0.223915 (rank : 74)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	144	Target Neighborhood Hits	825	Shared Neighborhood Hits	77
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

AF17_HUMAN
NC score	0.216695 (rank : 75)	θ value	0.365318 (rank : 84)
Query Neighborhood Hits	144	Target Neighborhood Hits	230	Shared Neighborhood Hits	60
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

AF10_MOUSE
NC score	0.203219 (rank : 76)	θ value	0.365318 (rank : 83)
Query Neighborhood Hits	144	Target Neighborhood Hits	182	Shared Neighborhood Hits	55
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

AF10_HUMAN
NC score	0.202782 (rank : 77)	θ value	0.365318 (rank : 82)
Query Neighborhood Hits	144	Target Neighborhood Hits	198	Shared Neighborhood Hits	53
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

TAF3_HUMAN
NC score	0.178556 (rank : 78)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	144	Target Neighborhood Hits	568	Shared Neighborhood Hits	68
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

CECR2_HUMAN
NC score	0.174237 (rank : 79)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	144	Target Neighborhood Hits	543	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

ATRX_MOUSE
NC score	0.169822 (rank : 80)	θ value	0.0563607 (rank : 73)
Query Neighborhood Hits	144	Target Neighborhood Hits	682	Shared Neighborhood Hits	39
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

ATRX_HUMAN
NC score	0.162898 (rank : 81)	θ value	0.0563607 (rank : 72)
Query Neighborhood Hits	144	Target Neighborhood Hits	842	Shared Neighborhood Hits	47
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

TAF3_MOUSE
NC score	0.161114 (rank : 82)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	144	Target Neighborhood Hits	463	Shared Neighborhood Hits	61
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

PHF22_MOUSE
NC score	0.161051 (rank : 83)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	144	Target Neighborhood Hits	89	Shared Neighborhood Hits	41
SwissProt Accessions	Q9D168, Q3U2Q5, Q921U2	Gene names	Ints12, Phf22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

ING3_HUMAN
NC score	0.160648 (rank : 84)	θ value	0.279714 (rank : 81)
Query Neighborhood Hits	144	Target Neighborhood Hits	178	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

ING5_HUMAN
NC score	0.159954 (rank : 85)	θ value	0.163984 (rank : 77)
Query Neighborhood Hits	144	Target Neighborhood Hits	65	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WYH8, Q9BS30	Gene names	ING5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5 (p28ING5).

JHD3A_MOUSE
NC score	0.158759 (rank : 86)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	144	Target Neighborhood Hits	85	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BW72, Q3UKM5, Q3UM81, Q3UWV2, Q6ZQ72, Q8K137	Gene names	Jmjd2a, Jhdm3a, Jmjd2, Kiaa0677
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

PCAF_HUMAN
NC score	0.156472 (rank : 87)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	144	Target Neighborhood Hits	68	Shared Neighborhood Hits	18
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

ING5_MOUSE
NC score	0.155718 (rank : 88)	θ value	0.163984 (rank : 78)
Query Neighborhood Hits	144	Target Neighborhood Hits	76	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D8Y8, Q3UL57, Q6P292, Q9CV64, Q9D9V8	Gene names	Ing5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5.

GCNL2_HUMAN
NC score	0.155556 (rank : 89)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	144	Target Neighborhood Hits	159	Shared Neighborhood Hits	24
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

BRD2_HUMAN
NC score	0.155352 (rank : 90)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	144	Target Neighborhood Hits	242	Shared Neighborhood Hits	27
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

JHD3C_MOUSE
NC score	0.154274 (rank : 91)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	144	Target Neighborhood Hits	84	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

PHF22_HUMAN
NC score	0.154160 (rank : 92)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	144	Target Neighborhood Hits	121	Shared Neighborhood Hits	39
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

JHD3A_HUMAN
NC score	0.154080 (rank : 93)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	144	Target Neighborhood Hits	78	Shared Neighborhood Hits	30
SwissProt Accessions	O75164, Q5VVB1	Gene names	JMJD2A, JHDM3A, JMJD2, KIAA0677
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3B_MOUSE
NC score	0.153383 (rank : 94)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	144	Target Neighborhood Hits	152	Shared Neighborhood Hits	34
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

GCNL2_MOUSE
NC score	0.151867 (rank : 95)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	144	Target Neighborhood Hits	146	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

JHD3C_HUMAN
NC score	0.151784 (rank : 96)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	144	Target Neighborhood Hits	91	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

JHD3B_HUMAN
NC score	0.151293 (rank : 97)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	144	Target Neighborhood Hits	128	Shared Neighborhood Hits	31
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

IPR1_MOUSE
NC score	0.146591 (rank : 98)	θ value	1.81305 (rank : 95)
Query Neighborhood Hits	144	Target Neighborhood Hits	65	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BVK9, Q3UCV7, Q80V00	Gene names	Ipr1, Ifi75
Domain Architecture	No domain graphic available
Description	Intracellular pathogen resistance protein 1.

BRD4_MOUSE
NC score	0.145855 (rank : 99)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	144	Target Neighborhood Hits	845	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BRD4_HUMAN
NC score	0.144960 (rank : 100)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	144	Target Neighborhood Hits	851	Shared Neighborhood Hits	43
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

DPF3_MOUSE
NC score	0.144666 (rank : 101)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	144	Target Neighborhood Hits	327	Shared Neighborhood Hits	14
SwissProt Accessions	P58269	Gene names	Dpf3, Cerd4
Domain Architecture	No domain graphic available
Description	Zinc-finger protein Dpf3 (cer-d4).

ING3_MOUSE
NC score	0.144015 (rank : 102)	θ value	0.365318 (rank : 85)
Query Neighborhood Hits	144	Target Neighborhood Hits	177	Shared Neighborhood Hits	42
SwissProt Accessions	Q8VEK6, Q99JS6, Q9ERB2	Gene names	Ing3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

SMCA2_HUMAN
NC score	0.143638 (rank : 103)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	144	Target Neighborhood Hits	503	Shared Neighborhood Hits	35
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SMCA4_HUMAN
NC score	0.142577 (rank : 104)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	144	Target Neighborhood Hits	597	Shared Neighborhood Hits	37
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

TAF1_HUMAN
NC score	0.141347 (rank : 105)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	144	Target Neighborhood Hits	136	Shared Neighborhood Hits	22
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

BRD8_HUMAN
NC score	0.140949 (rank : 106)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	144	Target Neighborhood Hits	292	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

BRD3_MOUSE
NC score	0.140610 (rank : 107)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	144	Target Neighborhood Hits	402	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

BRD3_HUMAN
NC score	0.140378 (rank : 108)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	144	Target Neighborhood Hits	369	Shared Neighborhood Hits	27
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BRDT_HUMAN
NC score	0.135948 (rank : 109)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	144	Target Neighborhood Hits	280	Shared Neighborhood Hits	25
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

BRDT_MOUSE
NC score	0.135539 (rank : 110)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	144	Target Neighborhood Hits	243	Shared Neighborhood Hits	24
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

TRI45_HUMAN
NC score	0.135423 (rank : 111)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	144	Target Neighborhood Hits	155	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

BRD8_MOUSE
NC score	0.135407 (rank : 112)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	144	Target Neighborhood Hits	422	Shared Neighborhood Hits	36
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

TAF1L_HUMAN
NC score	0.134742 (rank : 113)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	144	Target Neighborhood Hits	144	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZX4	Gene names	TAF1L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID 210 kDa subunit (TBP-associated factor 210 kDa) (TAF(II)210) (TBP-associated factor 1-like).

TRI45_MOUSE
NC score	0.134129 (rank : 114)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	144	Target Neighborhood Hits	155	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

EP300_HUMAN
NC score	0.127424 (rank : 115)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	144	Target Neighborhood Hits	821	Shared Neighborhood Hits	47
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

CBP_MOUSE
NC score	0.126395 (rank : 116)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	144	Target Neighborhood Hits	1051	Shared Neighborhood Hits	52
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

PB1_HUMAN
NC score	0.121052 (rank : 117)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	144	Target Neighborhood Hits	261	Shared Neighborhood Hits	23
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

CBP_HUMAN
NC score	0.120588 (rank : 118)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	144	Target Neighborhood Hits	941	Shared Neighborhood Hits	42
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

BRD9_MOUSE
NC score	0.120276 (rank : 119)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	144	Target Neighborhood Hits	84	Shared Neighborhood Hits	19
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

ING2_MOUSE
NC score	0.120020 (rank : 120)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	144	Target Neighborhood Hits	102	Shared Neighborhood Hits	34
SwissProt Accessions	Q9ESK4, Q80VI5, Q8BGU8	Gene names	Ing2, Ing1l
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein).

DPF3_HUMAN
NC score	0.120002 (rank : 121)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	144	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q92784, Q9H7Y5	Gene names	DPF3, CERD4
Domain Architecture	No domain graphic available
Description	Zinc-finger protein DPF3 (cer-d4).

ING2_HUMAN
NC score	0.117199 (rank : 122)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	144	Target Neighborhood Hits	101	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H160, O95698	Gene names	ING2, ING1L
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein) (ING1Lp) (p32).

SP100_HUMAN
NC score	0.115129 (rank : 123)	θ value	0.0330416 (rank : 67)
Query Neighborhood Hits	144	Target Neighborhood Hits	117	Shared Neighborhood Hits	13
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

BRD9_HUMAN
NC score	0.113488 (rank : 124)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	144	Target Neighborhood Hits	56	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H8M2, Q2XUS1, Q6UWU9, Q8IUS4, Q9H5Q5, Q9H7R9	Gene names	BRD9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS- 40.8).

BRD7_HUMAN
NC score	0.113053 (rank : 125)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	144	Target Neighborhood Hits	94	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

TCF19_HUMAN
NC score	0.110489 (rank : 126)	θ value	3.0926 (rank : 108)
Query Neighborhood Hits	144	Target Neighborhood Hits	124	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y242, Q13176, Q15967, Q5SQ89, Q5STD6, Q5STF5, Q9BUM2, Q9UBH7	Gene names	TCF19, SC1
Domain Architecture
Description	Transcription factor 19 (Transcription factor SC1).

BRD7_MOUSE
NC score	0.110364 (rank : 127)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	144	Target Neighborhood Hits	141	Shared Neighborhood Hits	21
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

PML_HUMAN
NC score	0.109615 (rank : 128)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	144	Target Neighborhood Hits	248	Shared Neighborhood Hits	18
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

CHD6_HUMAN
NC score	0.108881 (rank : 129)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	144	Target Neighborhood Hits	342	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CHD2_HUMAN
NC score	0.108091 (rank : 130)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	144	Target Neighborhood Hits	360	Shared Neighborhood Hits	14
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

PML_MOUSE
NC score	0.107884 (rank : 131)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	144	Target Neighborhood Hits	246	Shared Neighborhood Hits	13
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

ING1_MOUSE
NC score	0.107287 (rank : 132)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	144	Target Neighborhood Hits	71	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QXV3, Q9QUP8, Q9QXV4, Q9QZX3	Gene names	Ing1
Domain Architecture
Description	Inhibitor of growth protein 1.

CHD1_HUMAN
NC score	0.106856 (rank : 133)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	144	Target Neighborhood Hits	337	Shared Neighborhood Hits	12
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_MOUSE
NC score	0.106070 (rank : 134)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	144	Target Neighborhood Hits	266	Shared Neighborhood Hits	10
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

ING1_HUMAN
NC score	0.105927 (rank : 135)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	144	Target Neighborhood Hits	65	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UK53, O00532, O43658, Q9H007, Q9HD98, Q9HD99, Q9NS83, Q9P0U6, Q9UBC6, Q9UIJ1, Q9UIJ2, Q9UIJ3, Q9UIJ4, Q9UK52	Gene names	ING1
Domain Architecture
Description	Inhibitor of growth protein 1.

CHD9_HUMAN
NC score	0.105033 (rank : 136)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	144	Target Neighborhood Hits	343	Shared Neighborhood Hits	13
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

ING4_HUMAN
NC score	0.104576 (rank : 137)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	144	Target Neighborhood Hits	82	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UNL4, Q96E15, Q9H3J0	Gene names	ING4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

CHD8_HUMAN
NC score	0.103818 (rank : 138)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	144	Target Neighborhood Hits	235	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CHD9_MOUSE
NC score	0.103561 (rank : 139)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	144	Target Neighborhood Hits	427	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

ING4_MOUSE
NC score	0.103226 (rank : 140)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	144	Target Neighborhood Hits	93	Shared Neighborhood Hits	35
SwissProt Accessions	Q8C0D7, Q8C1S7, Q8K3Q5, Q8K3Q6, Q8K3Q7, Q9D7F9	Gene names	Ing4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

CXCC1_HUMAN
NC score	0.101278 (rank : 141)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	144	Target Neighborhood Hits	143	Shared Neighborhood Hits	43
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

JARD2_HUMAN
NC score	0.100077 (rank : 142)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	144	Target Neighborhood Hits	119	Shared Neighborhood Hits	8
SwissProt Accessions	Q92833, Q5U5L5	Gene names	JARID2, JMJ
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

ERCC6_HUMAN
NC score	0.099792 (rank : 143)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	144	Target Neighborhood Hits	247	Shared Neighborhood Hits	11
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

SMCA1_HUMAN
NC score	0.099499 (rank : 144)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	144	Target Neighborhood Hits	105	Shared Neighborhood Hits	8
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMCA1_MOUSE
NC score	0.099356 (rank : 145)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	144	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

SET1A_HUMAN
NC score	0.099176 (rank : 146)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	144	Target Neighborhood Hits	690	Shared Neighborhood Hits	28
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SMCA5_MOUSE
NC score	0.099098 (rank : 147)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	144	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

SMCA5_HUMAN
NC score	0.099038 (rank : 148)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	144	Target Neighborhood Hits	76	Shared Neighborhood Hits	7
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

DEAF1_MOUSE
NC score	0.097877 (rank : 149)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	144	Target Neighborhood Hits	70	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z1T5	Gene names	Deaf1
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR).

JARD2_MOUSE
NC score	0.097840 (rank : 150)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	144	Target Neighborhood Hits	169	Shared Neighborhood Hits	11
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

TRI56_MOUSE
NC score	0.097655 (rank : 151)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	144	Target Neighborhood Hits	255	Shared Neighborhood Hits	13
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI56_HUMAN
NC score	0.096834 (rank : 152)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	144	Target Neighborhood Hits	339	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

CXCC1_MOUSE
NC score	0.096325 (rank : 153)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	144	Target Neighborhood Hits	124	Shared Neighborhood Hits	43
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

SP100_MOUSE
NC score	0.095790 (rank : 154)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	144	Target Neighborhood Hits	32	Shared Neighborhood Hits	9
SwissProt Accessions	O35892, O35897, O88392, O88395	Gene names	Sp100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein).

DEAF1_HUMAN
NC score	0.094879 (rank : 155)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	144	Target Neighborhood Hits	67	Shared Neighborhood Hits	14
SwissProt Accessions	O75398, O15152, O75399, O75510, O75511, O75512, O75513, Q9UET1	Gene names	DEAF1, SPN, ZMYND5
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR) (Suppressin) (Zinc finger MYND domain-containing protein 5).

EP400_MOUSE
NC score	0.094674 (rank : 156)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	144	Target Neighborhood Hits	592	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

RAD54_HUMAN
NC score	0.094091 (rank : 157)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	144	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

EP400_HUMAN
NC score	0.094078 (rank : 158)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	144	Target Neighborhood Hits	556	Shared Neighborhood Hits	30
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

MYST2_HUMAN
NC score	0.092428 (rank : 159)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	144	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	O95251	Gene names	MYST2, HBO1, HBOa
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

MYST2_MOUSE
NC score	0.092392 (rank : 160)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	144	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q5SVQ0, Q5SVQ1, Q5SVQ2, Q5SVQ3, Q5SVQ7, Q6PGC6, Q80Y65	Gene names	Myst2, Hbo1
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

RAD54_MOUSE
NC score	0.092353 (rank : 161)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	144	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

TIP60_HUMAN
NC score	0.092211 (rank : 162)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	144	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q92993, O95624, Q13430, Q6GSE8, Q9BWK7	Gene names	HTATIP, TIP60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60) (HIV-1 Tat interactive protein) (cPLA(2)-interacting protein).

TIP60_MOUSE
NC score	0.092204 (rank : 163)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	144	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

SMRCD_MOUSE
NC score	0.092124 (rank : 164)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	144	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

SMRCD_HUMAN
NC score	0.092111 (rank : 165)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	144	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

S100R_MOUSE
NC score	0.092057 (rank : 166)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	144	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q99388	Gene names	D1Lub1, Sp100-rs
Domain Architecture
Description	Putative Sp100-related protein.

RA54B_HUMAN
NC score	0.091968 (rank : 167)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	144	Target Neighborhood Hits	54	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

RA54B_MOUSE
NC score	0.091871 (rank : 168)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	144	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

MYST1_HUMAN
NC score	0.091425 (rank : 169)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	144	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H7Z6, Q659G0, Q7LC17, Q8IY59, Q8WYB4, Q8WZ14, Q9HAC5, Q9NR35	Gene names	MYST1, MOF
Domain Architecture	No domain graphic available
Description	Probable histone acetyltransferase MYST1 (EC 2.3.1.48) (MYST protein 1) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (hMOF).

MYST1_MOUSE
NC score	0.091359 (rank : 170)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	144	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D1P2, Q3UIY0, Q8BJ69, Q8BJ76, Q8CI73	Gene names	Myst1, Mof
Domain Architecture	No domain graphic available
Description	Probable histone acetyltransferase MYST1 (EC 2.3.1.48) (MYST protein 1) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1).

INOC1_MOUSE
NC score	0.088863 (rank : 171)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	144	Target Neighborhood Hits	178	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

INOC1_HUMAN
NC score	0.088773 (rank : 172)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	144	Target Neighborhood Hits	181	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

SMAL1_MOUSE
NC score	0.087058 (rank : 173)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	144	Target Neighborhood Hits	157	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

SETD2_HUMAN
NC score	0.085882 (rank : 174)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	144	Target Neighborhood Hits	412	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

PHF7_HUMAN
NC score	0.085811 (rank : 175)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	144	Target Neighborhood Hits	71	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

BTAF1_HUMAN
NC score	0.085126 (rank : 176)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	144	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

SMAL1_HUMAN
NC score	0.084911 (rank : 177)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	144	Target Neighborhood Hits	174	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

DIDO1_HUMAN
NC score	0.083499 (rank : 178)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	144	Target Neighborhood Hits	960	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

JHD3D_MOUSE
NC score	0.081565 (rank : 179)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	144	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	Q3U2K5, Q2M1G7, Q8BI19	Gene names	Jmjd2d, Jhdm3d
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

JHD3D_HUMAN
NC score	0.080491 (rank : 180)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	144	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	Q6B0I6, Q9NT41, Q9NW76	Gene names	JMJD2D, JHDM3D
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

PHF7_MOUSE
NC score	0.079003 (rank : 181)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	144	Target Neighborhood Hits	65	Shared Neighborhood Hits	29
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

TRIM2_HUMAN
NC score	0.078941 (rank : 182)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	144	Target Neighborhood Hits	330	Shared Neighborhood Hits	14
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
NC score	0.078854 (rank : 183)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	144	Target Neighborhood Hits	331	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

PHF20_MOUSE
NC score	0.077990 (rank : 184)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	144	Target Neighborhood Hits	513	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

TRIM3_MOUSE
NC score	0.077821 (rank : 185)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	144	Target Neighborhood Hits	351	Shared Neighborhood Hits	15
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRIM3_HUMAN
NC score	0.077223 (rank : 186)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	144	Target Neighborhood Hits	357	Shared Neighborhood Hits	16
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

BRWD1_MOUSE
NC score	0.076343 (rank : 187)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	144	Target Neighborhood Hits	478	Shared Neighborhood Hits	25
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

SMRA3_MOUSE
NC score	0.074504 (rank : 188)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	144	Target Neighborhood Hits	267	Shared Neighborhood Hits	12
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

PHF20_HUMAN
NC score	0.074181 (rank : 189)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	144	Target Neighborhood Hits	394	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

SMRA3_HUMAN
NC score	0.074181 (rank : 190)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	144	Target Neighborhood Hits	265	Shared Neighborhood Hits	13
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

BRWD1_HUMAN
NC score	0.073373 (rank : 191)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	144	Target Neighborhood Hits	448	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

IWS1_MOUSE
NC score	0.073066 (rank : 192)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	144	Target Neighborhood Hits	1258	Shared Neighborhood Hits	40
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TRI42_MOUSE
NC score	0.072178 (rank : 193)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	144	Target Neighborhood Hits	316	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TTF2_MOUSE
NC score	0.071073 (rank : 194)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	144	Target Neighborhood Hits	364	Shared Neighborhood Hits	15
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

PHF11_HUMAN
NC score	0.069464 (rank : 195)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	144	Target Neighborhood Hits	42	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

TRI42_HUMAN
NC score	0.069335 (rank : 196)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	144	Target Neighborhood Hits	283	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

ARI5B_HUMAN
NC score	0.066398 (rank : 197)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	144	Target Neighborhood Hits	328	Shared Neighborhood Hits	26
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

DNM3L_MOUSE
NC score	0.065610 (rank : 198)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	144	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	Q9CWR8	Gene names	Dnmt3l
Domain Architecture	No domain graphic available
Description	DNA (cytosine-5)-methyltransferase 3-like.

IWS1_HUMAN
NC score	0.064972 (rank : 199)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	144	Target Neighborhood Hits	1241	Shared Neighborhood Hits	39
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TRI46_HUMAN
NC score	0.064883 (rank : 200)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	144	Target Neighborhood Hits	291	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI36_HUMAN
NC score	0.064350 (rank : 201)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	144	Target Neighborhood Hits	282	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

SUV92_HUMAN
NC score	0.064312 (rank : 202)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	144	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

EZH2_HUMAN
NC score	0.064092 (rank : 203)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	144	Target Neighborhood Hits	84	Shared Neighborhood Hits	7
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

TTF2_HUMAN
NC score	0.064091 (rank : 204)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	144	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

EZH1_MOUSE
NC score	0.063774 (rank : 205)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	144	Target Neighborhood Hits	126	Shared Neighborhood Hits	10
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

ARI3A_HUMAN
NC score	0.063724 (rank : 206)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	144	Target Neighborhood Hits	80	Shared Neighborhood Hits	10
SwissProt Accessions	Q99856, Q8IZA7	Gene names	ARID3A, DRIL1, DRX, E2FBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 3A (ARID domain- containing protein 3A) (B-cell regulator of IgH transcription) (Bright) (E2F-binding protein 1).

EZH1_HUMAN
NC score	0.063694 (rank : 207)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	144	Target Neighborhood Hits	121	Shared Neighborhood Hits	9
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

TRI46_MOUSE
NC score	0.063635 (rank : 208)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	144	Target Neighborhood Hits	287	Shared Neighborhood Hits	15
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

EZH2_MOUSE
NC score	0.063445 (rank : 209)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	144	Target Neighborhood Hits	86	Shared Neighborhood Hits	7
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

TRI63_HUMAN
NC score	0.063335 (rank : 210)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	144	Target Neighborhood Hits	298	Shared Neighborhood Hits	14
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

SUV92_MOUSE
NC score	0.062416 (rank : 211)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	144	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

NACAM_MOUSE
NC score	0.062164 (rank : 212)	θ value	2.36792 (rank : 99)
Query Neighborhood Hits	144	Target Neighborhood Hits	1866	Shared Neighborhood Hits	59
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NFX1_HUMAN
NC score	0.062056 (rank : 213)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	144	Target Neighborhood Hits	405	Shared Neighborhood Hits	34
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

PCLO_HUMAN
NC score	0.061796 (rank : 214)	θ value	1.38821 (rank : 94)
Query Neighborhood Hits	144	Target Neighborhood Hits	2046	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

ARI3A_MOUSE
NC score	0.061736 (rank : 215)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	144	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	Q62431	Gene names	Arid3a, Dri1, Dril1
Domain Architecture
Description	AT-rich interactive domain-containing protein 3A (ARID domain- containing protein 3A) (Dead ringer-like protein 1) (B-cell regulator of IgH transcription) (Bright).

PHF6_HUMAN
NC score	0.061715 (rank : 216)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	144	Target Neighborhood Hits	37	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

SETB2_HUMAN
NC score	0.061443 (rank : 217)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	144	Target Neighborhood Hits	62	Shared Neighborhood Hits	11
SwissProt Accessions	Q96T68, Q86UD6, Q96AI6	Gene names	SETDB2, CLLD8
Domain Architecture
Description	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein).

NIPBL_HUMAN
NC score	0.061436 (rank : 218)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	144	Target Neighborhood Hits	1311	Shared Neighborhood Hits	41
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

RAI1_MOUSE
NC score	0.061331 (rank : 219)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	144	Target Neighborhood Hits	344	Shared Neighborhood Hits	31
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

SUV91_HUMAN
NC score	0.061263 (rank : 220)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	144	Target Neighborhood Hits	63	Shared Neighborhood Hits	8
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

TRI36_MOUSE
NC score	0.061167 (rank : 221)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	144	Target Neighborhood Hits	266	Shared Neighborhood Hits	17
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRIM1_MOUSE
NC score	0.061028 (rank : 222)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	144	Target Neighborhood Hits	361	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

ARI1A_HUMAN
NC score	0.060968 (rank : 223)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	144	Target Neighborhood Hits	787	Shared Neighborhood Hits	28
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

TRIM1_HUMAN
NC score	0.060655 (rank : 224)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	144	Target Neighborhood Hits	345	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

SETD8_MOUSE
NC score	0.059699 (rank : 225)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	144	Target Neighborhood Hits	131	Shared Neighborhood Hits	10
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

RGS3_MOUSE
NC score	0.059545 (rank : 226)	θ value	0.21417 (rank : 79)
Query Neighborhood Hits	144	Target Neighborhood Hits	1621	Shared Neighborhood Hits	43
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

TXND2_HUMAN
NC score	0.059461 (rank : 227)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	144	Target Neighborhood Hits	793	Shared Neighborhood Hits	35
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

SUV91_MOUSE
NC score	0.058900 (rank : 228)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	144	Target Neighborhood Hits	69	Shared Neighborhood Hits	7
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

SETD8_HUMAN
NC score	0.058454 (rank : 229)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	144	Target Neighborhood Hits	114	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

MDC1_HUMAN
NC score	0.058395 (rank : 230)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	144	Target Neighborhood Hits	1446	Shared Neighborhood Hits	45
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

ATAD2_HUMAN
NC score	0.057758 (rank : 231)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	144	Target Neighborhood Hits	322	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

PHF6_MOUSE
NC score	0.057583 (rank : 232)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	144	Target Neighborhood Hits	39	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

SON_HUMAN
NC score	0.057455 (rank : 233)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	144	Target Neighborhood Hits	1568	Shared Neighborhood Hits	50
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

DOT1L_HUMAN
NC score	0.057380 (rank : 234)	θ value	0.0961366 (rank : 75)
Query Neighborhood Hits	144	Target Neighborhood Hits	660	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

AMBN_HUMAN
NC score	0.057290 (rank : 235)	θ value	0.0563607 (rank : 71)
Query Neighborhood Hits	144	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NP70, Q9H2X1, Q9H4L1	Gene names	AMBN
Domain Architecture
Description	Ameloblastin precursor.

RAI1_HUMAN
NC score	0.057190 (rank : 236)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	144	Target Neighborhood Hits	360	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

JHD1A_HUMAN
NC score	0.055691 (rank : 237)	θ value	1.38821 (rank : 92)
Query Neighborhood Hits	144	Target Neighborhood Hits	133	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

MUC7_HUMAN
NC score	0.055655 (rank : 238)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	144	Target Neighborhood Hits	538	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

TRI63_MOUSE
NC score	0.055097 (rank : 239)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	144	Target Neighborhood Hits	240	Shared Neighborhood Hits	13
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

ATAD2_MOUSE
NC score	0.054925 (rank : 240)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	144	Target Neighborhood Hits	167	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

GSCR1_HUMAN
NC score	0.053608 (rank : 241)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	144	Target Neighborhood Hits	674	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

PHF3_HUMAN
NC score	0.053168 (rank : 242)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	144	Target Neighborhood Hits	419	Shared Neighborhood Hits	28
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

RGS3_HUMAN
NC score	0.052756 (rank : 243)	θ value	0.813845 (rank : 89)
Query Neighborhood Hits	144	Target Neighborhood Hits	1375	Shared Neighborhood Hits	42
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

TRI29_HUMAN
NC score	0.052755 (rank : 244)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	144	Target Neighborhood Hits	273	Shared Neighborhood Hits	11
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TCF20_MOUSE
NC score	0.052414 (rank : 245)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	144	Target Neighborhood Hits	396	Shared Neighborhood Hits	29
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

ARI4A_HUMAN
NC score	0.052151 (rank : 246)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	144	Target Neighborhood Hits	434	Shared Neighborhood Hits	16
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

TCF20_HUMAN
NC score	0.052047 (rank : 247)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	144	Target Neighborhood Hits	323	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

PHF2_MOUSE
NC score	0.051739 (rank : 248)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	144	Target Neighborhood Hits	241	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

TP53B_MOUSE
NC score	0.051667 (rank : 249)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	144	Target Neighborhood Hits	644	Shared Neighborhood Hits	28
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TGON2_HUMAN
NC score	0.051622 (rank : 250)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	144	Target Neighborhood Hits	1037	Shared Neighborhood Hits	36
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

PHF2_HUMAN
NC score	0.051438 (rank : 251)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	144	Target Neighborhood Hits	208	Shared Neighborhood Hits	34
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

ARI1B_HUMAN
NC score	0.051101 (rank : 252)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	144	Target Neighborhood Hits	567	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

JHD1A_MOUSE
NC score	0.050963 (rank : 253)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	144	Target Neighborhood Hits	134	Shared Neighborhood Hits	24
SwissProt Accessions	P59997, Q3U1M5, Q3UR56, Q3V3Q1, Q69ZT4	Gene names	Fbxl11, Jhdm1a, Kiaa1004
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11).

NPBL_MOUSE
NC score	0.050790 (rank : 254)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	144	Target Neighborhood Hits	1041	Shared Neighborhood Hits	36
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

MDC1_MOUSE
NC score	0.050606 (rank : 255)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	144	Target Neighborhood Hits	998	Shared Neighborhood Hits	47
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

SRRM1_MOUSE
NC score	0.050591 (rank : 256)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	144	Target Neighborhood Hits	966	Shared Neighborhood Hits	35
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TRI37_HUMAN
NC score	0.050398 (rank : 257)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	144	Target Neighborhood Hits	307	Shared Neighborhood Hits	12
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
NC score	0.050331 (rank : 258)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	144	Target Neighborhood Hits	316	Shared Neighborhood Hits	12
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI55_HUMAN
NC score	0.050093 (rank : 259)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	144	Target Neighborhood Hits	292	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

BSN_MOUSE
NC score	0.048694 (rank : 260)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	144	Target Neighborhood Hits	2057	Shared Neighborhood Hits	47
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

LNP_MOUSE
NC score	0.041188 (rank : 261)	θ value	0.813845 (rank : 88)
Query Neighborhood Hits	144	Target Neighborhood Hits	83	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TQ95, Q69ZC5, Q6PAQ1, Q6PEN8	Gene names	Lnp, Kiaa1715, Uln
Domain Architecture	No domain graphic available
Description	Protein lunapark (Protein ulnaless).

NFH_MOUSE
NC score	0.040404 (rank : 262)	θ value	2.36792 (rank : 100)
Query Neighborhood Hits	144	Target Neighborhood Hits	2247	Shared Neighborhood Hits	59
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SEPT9_HUMAN
NC score	0.038488 (rank : 263)	θ value	0.0961366 (rank : 76)
Query Neighborhood Hits	144	Target Neighborhood Hits	706	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

BAT2_HUMAN
NC score	0.036995 (rank : 264)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	144	Target Neighborhood Hits	931	Shared Neighborhood Hits	29
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

EHMT2_MOUSE
NC score	0.036403 (rank : 265)	θ value	0.813845 (rank : 87)
Query Neighborhood Hits	144	Target Neighborhood Hits	750	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

PRAX_HUMAN
NC score	0.034987 (rank : 266)	θ value	1.06291 (rank : 91)
Query Neighborhood Hits	144	Target Neighborhood Hits	215	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

PRAX_MOUSE
NC score	0.034050 (rank : 267)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	144	Target Neighborhood Hits	199	Shared Neighborhood Hits	17
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

LNP_HUMAN
NC score	0.031247 (rank : 268)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	144	Target Neighborhood Hits	62	Shared Neighborhood Hits	5
SwissProt Accessions	Q9C0E8, Q2M2V8, Q2YD99, Q658W8, Q8N5V9, Q96MS5	Gene names	LNP, KIAA1715
Domain Architecture	No domain graphic available
Description	Protein lunapark.

CIC_HUMAN
NC score	0.028052 (rank : 269)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	144	Target Neighborhood Hits	992	Shared Neighborhood Hits	30
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

PCSK5_MOUSE
NC score	0.022446 (rank : 270)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	144	Target Neighborhood Hits	613	Shared Neighborhood Hits	17
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

XKR6_HUMAN
NC score	0.021896 (rank : 271)	θ value	0.47712 (rank : 86)
Query Neighborhood Hits	144	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q5GH73, Q8TBA0	Gene names	XKR6, C8orf21, C8orf7, XRG6
Domain Architecture	No domain graphic available
Description	XK-related protein 6.

E2F4_HUMAN
NC score	0.016481 (rank : 272)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	144	Target Neighborhood Hits	188	Shared Neighborhood Hits	11
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

SHC1_HUMAN
NC score	0.016457 (rank : 273)	θ value	1.81305 (rank : 97)
Query Neighborhood Hits	144	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SYAC_HUMAN
NC score	0.016291 (rank : 274)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	144	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	P49588, Q53GV7, Q96FA0	Gene names	AARS
Domain Architecture
Description	Alanyl-tRNA synthetase, cytoplasmic (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS) (NY-REN-42 antigen).

SYAC_MOUSE
NC score	0.016152 (rank : 275)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	144	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGQ7, Q8BXR0	Gene names	Aars
Domain Architecture
Description	Alanyl-tRNA synthetase, cytoplasmic (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS).

SHC1_MOUSE
NC score	0.015296 (rank : 276)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	144	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

RPGF1_HUMAN
NC score	0.014947 (rank : 277)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	144	Target Neighborhood Hits	262	Shared Neighborhood Hits	8
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

SYNP2_MOUSE
NC score	0.014848 (rank : 278)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	144	Target Neighborhood Hits	252	Shared Neighborhood Hits	11
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

SLIK1_MOUSE
NC score	0.014799 (rank : 279)	θ value	0.21417 (rank : 80)
Query Neighborhood Hits	144	Target Neighborhood Hits	333	Shared Neighborhood Hits	7
SwissProt Accessions	Q810C1, Q9CXL0	Gene names	Slitrk1, Sltk1
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor.

PLCB1_HUMAN
NC score	0.012770 (rank : 280)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	144	Target Neighborhood Hits	614	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

SLIK1_HUMAN
NC score	0.011943 (rank : 281)	θ value	1.81305 (rank : 98)
Query Neighborhood Hits	144	Target Neighborhood Hits	297	Shared Neighborhood Hits	5
SwissProt Accessions	Q96PX8, Q5U5I6, Q96SF9	Gene names	SLITRK1, KIAA1910, LRRC12
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor (Leucine-rich repeat-containing protein 12).

MAGA5_HUMAN
NC score	0.011797 (rank : 282)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	144	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	P43359	Gene names	MAGEA5, MAGE5
Domain Architecture
Description	Melanoma-associated antigen 5 (MAGE-5 antigen).

MMRN1_HUMAN
NC score	0.009942 (rank : 283)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	144	Target Neighborhood Hits	636	Shared Neighborhood Hits	8
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

WN10A_MOUSE
NC score	0.009900 (rank : 284)	θ value	3.0926 (rank : 109)
Query Neighborhood Hits	144	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	P70701	Gene names	Wnt10a
Domain Architecture
Description	Protein Wnt-10a precursor.

WNT2B_HUMAN
NC score	0.009891 (rank : 285)	θ value	3.0926 (rank : 110)
Query Neighborhood Hits	144	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q93097, O14903, Q9HDC1, Q9HDC2	Gene names	WNT2B, WNT13
Domain Architecture
Description	Protein Wnt-2b precursor (Wnt-13).

WNT2B_MOUSE
NC score	0.009882 (rank : 286)	θ value	3.0926 (rank : 111)
Query Neighborhood Hits	144	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	O70283, O88530	Gene names	Wnt2b, Wnt13
Domain Architecture
Description	Protein Wnt-2b precursor (Wnt-13).

FYV1_MOUSE
NC score	0.009722 (rank : 287)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	144	Target Neighborhood Hits	191	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

AMFR_MOUSE
NC score	0.008967 (rank : 288)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	144	Target Neighborhood Hits	208	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

LAMA5_MOUSE
NC score	0.008295 (rank : 289)	θ value	1.38821 (rank : 93)
Query Neighborhood Hits	144	Target Neighborhood Hits	828	Shared Neighborhood Hits	13
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

REG3G_HUMAN
NC score	0.008125 (rank : 290)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	144	Target Neighborhood Hits	86	Shared Neighborhood Hits	2
SwissProt Accessions	Q6UW15, Q6FH18	Gene names	REG3G, PAP1B
Domain Architecture	No domain graphic available
Description	Regenerating islet-derived protein 3 gamma precursor (Reg III-gamma) (Pancreatitis-associated protein 1B) (PAP IB).

NCA11_MOUSE
NC score	0.007314 (rank : 291)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	144	Target Neighborhood Hits	661	Shared Neighborhood Hits	17
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

PIDD_HUMAN
NC score	0.006007 (rank : 292)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	144	Target Neighborhood Hits	271	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HB75, Q59FD1, Q59H10, Q59HC7, Q7Z4P8, Q8NC89, Q8NDL2, Q96C25, Q9NRE6	Gene names	LRDD, PIDD
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and death domain-containing protein (p53-induced protein with a death domain).

CEND1_HUMAN
NC score	0.005808 (rank : 293)	θ value	4.03905 (rank : 112)
Query Neighborhood Hits	144	Target Neighborhood Hits	284	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

LAMB2_HUMAN
NC score	0.004456 (rank : 294)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	144	Target Neighborhood Hits	692	Shared Neighborhood Hits	9
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

NKX24_HUMAN
NC score	0.004399 (rank : 295)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	144	Target Neighborhood Hits	366	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H2Z4	Gene names	NKX2-4, NKX2D
Domain Architecture
Description	Homeobox protein Nkx-2.4 (Homeobox protein NKX2.4) (Homeobox protein NK-2 homolog D).

LAMA1_MOUSE
NC score	0.004029 (rank : 296)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	144	Target Neighborhood Hits	838	Shared Neighborhood Hits	10
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

EGFL7_MOUSE
NC score	0.003040 (rank : 297)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	144	Target Neighborhood Hits	287	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

ZN516_MOUSE
NC score	0.002870 (rank : 298)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	144	Target Neighborhood Hits	1197	Shared Neighborhood Hits	19
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

RAI14_HUMAN
NC score	0.002846 (rank : 299)	θ value	2.36792 (rank : 101)
Query Neighborhood Hits	144	Target Neighborhood Hits	1367	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

SALL3_HUMAN
NC score	0.001906 (rank : 300)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	144	Target Neighborhood Hits	1066	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

K2C7_HUMAN
NC score	0.000324 (rank : 301)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	144	Target Neighborhood Hits	369	Shared Neighborhood Hits	4
SwissProt Accessions	P08729, Q92676, Q9BUD8, Q9Y3R7	Gene names	KRT7, SCL
Domain Architecture
Description	Keratin, type II cytoskeletal 7 (Cytokeratin-7) (CK-7) (Keratin-7) (K7) (Sarcolectin).

GLI3_HUMAN
NC score	-0.001043 (rank : 302)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	144	Target Neighborhood Hits	871	Shared Neighborhood Hits	18
SwissProt Accessions	P10071, O75219, Q9UDT5, Q9UJ39	Gene names	GLI3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

KLF16_MOUSE
NC score	-0.001831 (rank : 303)	θ value	1.81305 (rank : 96)
Query Neighborhood Hits	144	Target Neighborhood Hits	719	Shared Neighborhood Hits	10
SwissProt Accessions	P58334, Q3U3Y4, Q8C8S2	Gene names	Klf16, Bteb4, Drrf
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 16 (Transcription factor BTEB4) (Basic transcription element-binding protein 4) (BTE-binding protein 4) (Dopamine receptor-regulating factor).

ZSCA1_HUMAN
NC score	-0.002727 (rank : 304)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	144	Target Neighborhood Hits	724	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NBB4, Q6WLH8, Q86WS8	Gene names	ZSCAN1
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 1.

ZFP38_HUMAN
NC score	-0.002760 (rank : 305)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	144	Target Neighborhood Hits	766	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y5A6, Q9H0B5	Gene names	ZNF38, ZFP38, ZSCAN21
Domain Architecture
Description	Zinc finger protein 38 homolog (Zfp-38) (Zinc finger and SCAN domain- containing protein 21) (NY-REN-21 antigen).

ZN606_HUMAN
NC score	-0.003128 (rank : 306)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	144	Target Neighborhood Hits	749	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WXB4, Q8NE04, Q96JH5	Gene names	ZNF606, KIAA1852, ZNF328
Domain Architecture
Description	Zinc finger protein 606 (Zinc finger protein 328).