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Network neighborhood for query Sequence : DNM3L_MOUSE

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DNM3L_MOUSE
SwissProt Accessions	Q9CWR8	Gene names	Dnmt3l
Domain Architecture	No domain graphic available
Description	DNA (cytosine-5)-methyltransferase 3-like.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DNM3L_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	26	Target Neighborhood Hits	26	Shared Neighborhood Hits	26
SwissProt Accessions	Q9CWR8	Gene names	Dnmt3l
Domain Architecture	No domain graphic available
Description	DNA (cytosine-5)-methyltransferase 3-like.

DNM3L_HUMAN
θ value	6.40027e-139 (rank : 2)	NC score	0.992073 (rank : 2)
Query Neighborhood Hits	26	Target Neighborhood Hits	21	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UJW3, Q9BUJ4	Gene names	DNMT3L
Domain Architecture	No domain graphic available
Description	DNA (cytosine-5)-methyltransferase 3-like.

DNM3B_MOUSE
θ value	1.6097e-65 (rank : 3)	NC score	0.906055 (rank : 3)
Query Neighborhood Hits	26	Target Neighborhood Hits	61	Shared Neighborhood Hits	16
SwissProt Accessions	O88509, O88510, O88511	Gene names	Dnmt3b
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase MmuIIIB) (DNA MTase MmuIIIB) (M.MmuIIIB).

DNM3A_HUMAN
θ value	4.38363e-63 (rank : 4)	NC score	0.894756 (rank : 6)
Query Neighborhood Hits	26	Target Neighborhood Hits	104	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y6K1, Q8WXU9	Gene names	DNMT3A
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA).

DNM3A_MOUSE
θ value	5.7252e-63 (rank : 5)	NC score	0.898085 (rank : 5)
Query Neighborhood Hits	26	Target Neighborhood Hits	91	Shared Neighborhood Hits	15
SwissProt Accessions	O88508, Q3UH24, Q8CJ60, Q922J0, Q9CSE1	Gene names	Dnmt3a
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA).

DNM3B_HUMAN
θ value	2.40537e-61 (rank : 6)	NC score	0.905309 (rank : 4)
Query Neighborhood Hits	26	Target Neighborhood Hits	59	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UBC3, Q9UBD4, Q9UJQ5, Q9UKA6, Q9UNE5, Q9Y5R9, Q9Y5S0	Gene names	DNMT3B
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase HsaIIIB) (DNA MTase HsaIIIB) (M.HsaIIIB).

ATRX_HUMAN
θ value	0.00020696 (rank : 7)	NC score	0.190069 (rank : 9)
Query Neighborhood Hits	26	Target Neighborhood Hits	842	Shared Neighborhood Hits	24
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

ATRX_MOUSE
θ value	0.000270298 (rank : 8)	NC score	0.193382 (rank : 8)
Query Neighborhood Hits	26	Target Neighborhood Hits	682	Shared Neighborhood Hits	25
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

CHD5_HUMAN
θ value	0.0193708 (rank : 9)	NC score	0.117536 (rank : 12)
Query Neighborhood Hits	26	Target Neighborhood Hits	349	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

PF21A_HUMAN
θ value	0.0193708 (rank : 10)	NC score	0.143364 (rank : 10)
Query Neighborhood Hits	26	Target Neighborhood Hits	303	Shared Neighborhood Hits	23
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

CHD3_HUMAN
θ value	0.0431538 (rank : 11)	NC score	0.111985 (rank : 13)
Query Neighborhood Hits	26	Target Neighborhood Hits	397	Shared Neighborhood Hits	22
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD4_HUMAN
θ value	0.0563607 (rank : 12)	NC score	0.111684 (rank : 14)
Query Neighborhood Hits	26	Target Neighborhood Hits	365	Shared Neighborhood Hits	22
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	0.0563607 (rank : 13)	NC score	0.111082 (rank : 15)
Query Neighborhood Hits	26	Target Neighborhood Hits	408	Shared Neighborhood Hits	22
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

PF21A_MOUSE
θ value	0.0563607 (rank : 14)	NC score	0.143255 (rank : 11)
Query Neighborhood Hits	26	Target Neighborhood Hits	285	Shared Neighborhood Hits	24
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

TIF1A_HUMAN
θ value	0.279714 (rank : 15)	NC score	0.083587 (rank : 16)
Query Neighborhood Hits	26	Target Neighborhood Hits	327	Shared Neighborhood Hits	19
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1A_MOUSE
θ value	0.365318 (rank : 16)	NC score	0.082267 (rank : 18)
Query Neighborhood Hits	26	Target Neighborhood Hits	307	Shared Neighborhood Hits	19
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1G_HUMAN
θ value	0.47712 (rank : 17)	NC score	0.079411 (rank : 21)
Query Neighborhood Hits	26	Target Neighborhood Hits	410	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	0.47712 (rank : 18)	NC score	0.080169 (rank : 20)
Query Neighborhood Hits	26	Target Neighborhood Hits	498	Shared Neighborhood Hits	20
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

CCDC7_HUMAN
θ value	1.06291 (rank : 19)	NC score	0.034771 (rank : 40)
Query Neighborhood Hits	26	Target Neighborhood Hits	253	Shared Neighborhood Hits	4
SwissProt Accessions	Q96M83, Q8IVQ0, Q8NEQ0	Gene names	CCDC7
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 7.

STK10_HUMAN
θ value	1.06291 (rank : 20)	NC score	0.003487 (rank : 42)
Query Neighborhood Hits	26	Target Neighborhood Hits	1921	Shared Neighborhood Hits	8
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TRI66_MOUSE
θ value	1.81305 (rank : 21)	NC score	0.077189 (rank : 22)
Query Neighborhood Hits	26	Target Neighborhood Hits	491	Shared Neighborhood Hits	18
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

MASTL_HUMAN
θ value	3.0926 (rank : 22)	NC score	0.003059 (rank : 43)
Query Neighborhood Hits	26	Target Neighborhood Hits	894	Shared Neighborhood Hits	4
SwissProt Accessions	Q96GX5, Q5T8D5, Q5T8D7, Q8NCD6, Q96SJ5	Gene names	MASTL, THC2
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

NSD1_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.076329 (rank : 23)
Query Neighborhood Hits	26	Target Neighborhood Hits	427	Shared Neighborhood Hits	23
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	3.0926 (rank : 24)	NC score	0.065916 (rank : 28)
Query Neighborhood Hits	26	Target Neighborhood Hits	472	Shared Neighborhood Hits	19
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

TRI66_HUMAN
θ value	5.27518 (rank : 25)	NC score	0.070952 (rank : 24)
Query Neighborhood Hits	26	Target Neighborhood Hits	479	Shared Neighborhood Hits	17
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TPR_HUMAN
θ value	8.99809 (rank : 26)	NC score	0.005523 (rank : 41)
Query Neighborhood Hits	26	Target Neighborhood Hits	1921	Shared Neighborhood Hits	10
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

AIRE_HUMAN
θ value	θ > 10 (rank : 27)	NC score	0.065610 (rank : 29)
Query Neighborhood Hits	26	Target Neighborhood Hits	144	Shared Neighborhood Hits	16
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	θ > 10 (rank : 28)	NC score	0.065331 (rank : 30)
Query Neighborhood Hits	26	Target Neighborhood Hits	196	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

LY10_HUMAN
θ value	θ > 10 (rank : 29)	NC score	0.065177 (rank : 31)
Query Neighborhood Hits	26	Target Neighborhood Hits	151	Shared Neighborhood Hits	18
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

MBD5_HUMAN
θ value	θ > 10 (rank : 30)	NC score	0.080928 (rank : 19)
Query Neighborhood Hits	26	Target Neighborhood Hits	176	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

MSH6_MOUSE
θ value	θ > 10 (rank : 31)	NC score	0.050215 (rank : 39)
Query Neighborhood Hits	26	Target Neighborhood Hits	55	Shared Neighborhood Hits	7
SwissProt Accessions	P54276, O54710	Gene names	Msh6, Gtmbp
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

PF21B_HUMAN
θ value	θ > 10 (rank : 32)	NC score	0.067062 (rank : 27)
Query Neighborhood Hits	26	Target Neighborhood Hits	197	Shared Neighborhood Hits	14
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_MOUSE
θ value	θ > 10 (rank : 33)	NC score	0.064465 (rank : 32)
Query Neighborhood Hits	26	Target Neighborhood Hits	278	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF12_HUMAN
θ value	θ > 10 (rank : 34)	NC score	0.057085 (rank : 34)
Query Neighborhood Hits	26	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	θ > 10 (rank : 35)	NC score	0.056810 (rank : 35)
Query Neighborhood Hits	26	Target Neighborhood Hits	172	Shared Neighborhood Hits	16
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PKCB1_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.057502 (rank : 33)
Query Neighborhood Hits	26	Target Neighborhood Hits	488	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

PWWP2_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.277762 (rank : 7)
Query Neighborhood Hits	26	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q6NUJ5, Q5SZI0, Q6ZQX5, Q96F43	Gene names	PWWP2
Domain Architecture	No domain graphic available
Description	PWWP domain-containing protein 2.

RAD54_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.050348 (rank : 38)
Query Neighborhood Hits	26	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

SP110_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.082290 (rank : 17)
Query Neighborhood Hits	26	Target Neighborhood Hits	141	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

TIF1B_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.055211 (rank : 36)
Query Neighborhood Hits	26	Target Neighborhood Hits	312	Shared Neighborhood Hits	15
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
θ value	θ > 10 (rank : 41)	NC score	0.054991 (rank : 37)
Query Neighborhood Hits	26	Target Neighborhood Hits	276	Shared Neighborhood Hits	15
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

ZMY11_HUMAN
θ value	θ > 10 (rank : 42)	NC score	0.070026 (rank : 26)
Query Neighborhood Hits	26	Target Neighborhood Hits	201	Shared Neighborhood Hits	20
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

ZMY11_MOUSE
θ value	θ > 10 (rank : 43)	NC score	0.070071 (rank : 25)
Query Neighborhood Hits	26	Target Neighborhood Hits	198	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

Hits sorted by NC score

DNM3L_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	26	Target Neighborhood Hits	26	Shared Neighborhood Hits	26
SwissProt Accessions	Q9CWR8	Gene names	Dnmt3l
Domain Architecture	No domain graphic available
Description	DNA (cytosine-5)-methyltransferase 3-like.

DNM3L_HUMAN
NC score	0.992073 (rank : 2)	θ value	6.40027e-139 (rank : 2)
Query Neighborhood Hits	26	Target Neighborhood Hits	21	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UJW3, Q9BUJ4	Gene names	DNMT3L
Domain Architecture	No domain graphic available
Description	DNA (cytosine-5)-methyltransferase 3-like.

DNM3B_MOUSE
NC score	0.906055 (rank : 3)	θ value	1.6097e-65 (rank : 3)
Query Neighborhood Hits	26	Target Neighborhood Hits	61	Shared Neighborhood Hits	16
SwissProt Accessions	O88509, O88510, O88511	Gene names	Dnmt3b
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase MmuIIIB) (DNA MTase MmuIIIB) (M.MmuIIIB).

DNM3B_HUMAN
NC score	0.905309 (rank : 4)	θ value	2.40537e-61 (rank : 6)
Query Neighborhood Hits	26	Target Neighborhood Hits	59	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UBC3, Q9UBD4, Q9UJQ5, Q9UKA6, Q9UNE5, Q9Y5R9, Q9Y5S0	Gene names	DNMT3B
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase HsaIIIB) (DNA MTase HsaIIIB) (M.HsaIIIB).

DNM3A_MOUSE
NC score	0.898085 (rank : 5)	θ value	5.7252e-63 (rank : 5)
Query Neighborhood Hits	26	Target Neighborhood Hits	91	Shared Neighborhood Hits	15
SwissProt Accessions	O88508, Q3UH24, Q8CJ60, Q922J0, Q9CSE1	Gene names	Dnmt3a
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA).

DNM3A_HUMAN
NC score	0.894756 (rank : 6)	θ value	4.38363e-63 (rank : 4)
Query Neighborhood Hits	26	Target Neighborhood Hits	104	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y6K1, Q8WXU9	Gene names	DNMT3A
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA).

PWWP2_HUMAN
NC score	0.277762 (rank : 7)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	26	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q6NUJ5, Q5SZI0, Q6ZQX5, Q96F43	Gene names	PWWP2
Domain Architecture	No domain graphic available
Description	PWWP domain-containing protein 2.

ATRX_MOUSE
NC score	0.193382 (rank : 8)	θ value	0.000270298 (rank : 8)
Query Neighborhood Hits	26	Target Neighborhood Hits	682	Shared Neighborhood Hits	25
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

ATRX_HUMAN
NC score	0.190069 (rank : 9)	θ value	0.00020696 (rank : 7)
Query Neighborhood Hits	26	Target Neighborhood Hits	842	Shared Neighborhood Hits	24
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

PF21A_HUMAN
NC score	0.143364 (rank : 10)	θ value	0.0193708 (rank : 10)
Query Neighborhood Hits	26	Target Neighborhood Hits	303	Shared Neighborhood Hits	23
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
NC score	0.143255 (rank : 11)	θ value	0.0563607 (rank : 14)
Query Neighborhood Hits	26	Target Neighborhood Hits	285	Shared Neighborhood Hits	24
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

CHD5_HUMAN
NC score	0.117536 (rank : 12)	θ value	0.0193708 (rank : 9)
Query Neighborhood Hits	26	Target Neighborhood Hits	349	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHD3_HUMAN
NC score	0.111985 (rank : 13)	θ value	0.0431538 (rank : 11)
Query Neighborhood Hits	26	Target Neighborhood Hits	397	Shared Neighborhood Hits	22
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD4_HUMAN
NC score	0.111684 (rank : 14)	θ value	0.0563607 (rank : 12)
Query Neighborhood Hits	26	Target Neighborhood Hits	365	Shared Neighborhood Hits	22
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
NC score	0.111082 (rank : 15)	θ value	0.0563607 (rank : 13)
Query Neighborhood Hits	26	Target Neighborhood Hits	408	Shared Neighborhood Hits	22
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

TIF1A_HUMAN
NC score	0.083587 (rank : 16)	θ value	0.279714 (rank : 15)
Query Neighborhood Hits	26	Target Neighborhood Hits	327	Shared Neighborhood Hits	19
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

SP110_HUMAN
NC score	0.082290 (rank : 17)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	26	Target Neighborhood Hits	141	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

TIF1A_MOUSE
NC score	0.082267 (rank : 18)	θ value	0.365318 (rank : 16)
Query Neighborhood Hits	26	Target Neighborhood Hits	307	Shared Neighborhood Hits	19
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

MBD5_HUMAN
NC score	0.080928 (rank : 19)	θ value	θ > 10 (rank : 30)
Query Neighborhood Hits	26	Target Neighborhood Hits	176	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

TIF1G_MOUSE
NC score	0.080169 (rank : 20)	θ value	0.47712 (rank : 18)
Query Neighborhood Hits	26	Target Neighborhood Hits	498	Shared Neighborhood Hits	20
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TIF1G_HUMAN
NC score	0.079411 (rank : 21)	θ value	0.47712 (rank : 17)
Query Neighborhood Hits	26	Target Neighborhood Hits	410	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TRI66_MOUSE
NC score	0.077189 (rank : 22)	θ value	1.81305 (rank : 21)
Query Neighborhood Hits	26	Target Neighborhood Hits	491	Shared Neighborhood Hits	18
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

NSD1_HUMAN
NC score	0.076329 (rank : 23)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	26	Target Neighborhood Hits	427	Shared Neighborhood Hits	23
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

TRI66_HUMAN
NC score	0.070952 (rank : 24)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	26	Target Neighborhood Hits	479	Shared Neighborhood Hits	17
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

ZMY11_MOUSE
NC score	0.070071 (rank : 25)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	26	Target Neighborhood Hits	198	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

ZMY11_HUMAN
NC score	0.070026 (rank : 26)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	26	Target Neighborhood Hits	201	Shared Neighborhood Hits	20
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

PF21B_HUMAN
NC score	0.067062 (rank : 27)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	26	Target Neighborhood Hits	197	Shared Neighborhood Hits	14
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

NSD1_MOUSE
NC score	0.065916 (rank : 28)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	26	Target Neighborhood Hits	472	Shared Neighborhood Hits	19
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

AIRE_HUMAN
NC score	0.065610 (rank : 29)	θ value	θ > 10 (rank : 27)
Query Neighborhood Hits	26	Target Neighborhood Hits	144	Shared Neighborhood Hits	16
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
NC score	0.065331 (rank : 30)	θ value	θ > 10 (rank : 28)
Query Neighborhood Hits	26	Target Neighborhood Hits	196	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

LY10_HUMAN
NC score	0.065177 (rank : 31)	θ value	θ > 10 (rank : 29)
Query Neighborhood Hits	26	Target Neighborhood Hits	151	Shared Neighborhood Hits	18
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

PF21B_MOUSE
NC score	0.064465 (rank : 32)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	26	Target Neighborhood Hits	278	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PKCB1_HUMAN
NC score	0.057502 (rank : 33)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	26	Target Neighborhood Hits	488	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

PHF12_HUMAN
NC score	0.057085 (rank : 34)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	26	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
NC score	0.056810 (rank : 35)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	26	Target Neighborhood Hits	172	Shared Neighborhood Hits	16
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

TIF1B_HUMAN
NC score	0.055211 (rank : 36)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	26	Target Neighborhood Hits	312	Shared Neighborhood Hits	15
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
NC score	0.054991 (rank : 37)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	26	Target Neighborhood Hits	276	Shared Neighborhood Hits	15
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

RAD54_HUMAN
NC score	0.050348 (rank : 38)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	26	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

MSH6_MOUSE
NC score	0.050215 (rank : 39)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	26	Target Neighborhood Hits	55	Shared Neighborhood Hits	7
SwissProt Accessions	P54276, O54710	Gene names	Msh6, Gtmbp
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

CCDC7_HUMAN
NC score	0.034771 (rank : 40)	θ value	1.06291 (rank : 19)
Query Neighborhood Hits	26	Target Neighborhood Hits	253	Shared Neighborhood Hits	4
SwissProt Accessions	Q96M83, Q8IVQ0, Q8NEQ0	Gene names	CCDC7
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 7.

TPR_HUMAN
NC score	0.005523 (rank : 41)	θ value	8.99809 (rank : 26)
Query Neighborhood Hits	26	Target Neighborhood Hits	1921	Shared Neighborhood Hits	10
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

STK10_HUMAN
NC score	0.003487 (rank : 42)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	26	Target Neighborhood Hits	1921	Shared Neighborhood Hits	8
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

MASTL_HUMAN
NC score	0.003059 (rank : 43)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	26	Target Neighborhood Hits	894	Shared Neighborhood Hits	4
SwissProt Accessions	Q96GX5, Q5T8D5, Q5T8D7, Q8NCD6, Q96SJ5	Gene names	MASTL, THC2
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).