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Network neighborhood for query Sequence : DNM3B_MOUSE

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DNM3B_MOUSE
SwissProt Accessions	O88509, O88510, O88511	Gene names	Dnmt3b
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase MmuIIIB) (DNA MTase MmuIIIB) (M.MmuIIIB).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DNM3A_HUMAN
θ value	0 (rank : 1)	NC score	0.973003 (rank : 4)
Query Neighborhood Hits	61	Target Neighborhood Hits	104	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y6K1, Q8WXU9	Gene names	DNMT3A
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA).

DNM3A_MOUSE
θ value	0 (rank : 2)	NC score	0.976615 (rank : 3)
Query Neighborhood Hits	61	Target Neighborhood Hits	91	Shared Neighborhood Hits	29
SwissProt Accessions	O88508, Q3UH24, Q8CJ60, Q922J0, Q9CSE1	Gene names	Dnmt3a
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA).

DNM3B_HUMAN
θ value	0 (rank : 3)	NC score	0.995391 (rank : 2)
Query Neighborhood Hits	61	Target Neighborhood Hits	59	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UBC3, Q9UBD4, Q9UJQ5, Q9UKA6, Q9UNE5, Q9Y5R9, Q9Y5S0	Gene names	DNMT3B
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase HsaIIIB) (DNA MTase HsaIIIB) (M.HsaIIIB).

DNM3B_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	61	Target Neighborhood Hits	61	Shared Neighborhood Hits	61
SwissProt Accessions	O88509, O88510, O88511	Gene names	Dnmt3b
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase MmuIIIB) (DNA MTase MmuIIIB) (M.MmuIIIB).

DNM3L_HUMAN
θ value	6.53529e-67 (rank : 5)	NC score	0.913976 (rank : 5)
Query Neighborhood Hits	61	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UJW3, Q9BUJ4	Gene names	DNMT3L
Domain Architecture	No domain graphic available
Description	DNA (cytosine-5)-methyltransferase 3-like.

DNM3L_MOUSE
θ value	1.6097e-65 (rank : 6)	NC score	0.906055 (rank : 6)
Query Neighborhood Hits	61	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	Q9CWR8	Gene names	Dnmt3l
Domain Architecture	No domain graphic available
Description	DNA (cytosine-5)-methyltransferase 3-like.

PWWP2_HUMAN
θ value	3.64472e-09 (rank : 7)	NC score	0.461210 (rank : 7)
Query Neighborhood Hits	61	Target Neighborhood Hits	80	Shared Neighborhood Hits	21
SwissProt Accessions	Q6NUJ5, Q5SZI0, Q6ZQX5, Q96F43	Gene names	PWWP2
Domain Architecture	No domain graphic available
Description	PWWP domain-containing protein 2.

ATRX_HUMAN
θ value	1.53129e-07 (rank : 8)	NC score	0.188307 (rank : 9)
Query Neighborhood Hits	61	Target Neighborhood Hits	842	Shared Neighborhood Hits	31
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

ATRX_MOUSE
θ value	7.59969e-07 (rank : 9)	NC score	0.191503 (rank : 8)
Query Neighborhood Hits	61	Target Neighborhood Hits	682	Shared Neighborhood Hits	32
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

MSH6_HUMAN
θ value	0.0193708 (rank : 10)	NC score	0.110759 (rank : 12)
Query Neighborhood Hits	61	Target Neighborhood Hits	81	Shared Neighborhood Hits	22
SwissProt Accessions	P52701, O43706, O43917, Q8TCX4, Q9BTB5	Gene names	MSH6, GTBP
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

MSH6_MOUSE
θ value	0.0252991 (rank : 11)	NC score	0.117777 (rank : 11)
Query Neighborhood Hits	61	Target Neighborhood Hits	55	Shared Neighborhood Hits	21
SwissProt Accessions	P54276, O54710	Gene names	Msh6, Gtmbp
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

HDGF_HUMAN
θ value	0.0431538 (rank : 12)	NC score	0.104382 (rank : 13)
Query Neighborhood Hits	61	Target Neighborhood Hits	61	Shared Neighborhood Hits	18
SwissProt Accessions	P51858, Q5SZ09	Gene names	HDGF, HMG1L2
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF) (High-mobility group protein 1- like 2) (HMG-1L2).

CHD3_HUMAN
θ value	0.0736092 (rank : 13)	NC score	0.087228 (rank : 21)
Query Neighborhood Hits	61	Target Neighborhood Hits	397	Shared Neighborhood Hits	25
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD5_HUMAN
θ value	0.0736092 (rank : 14)	NC score	0.091330 (rank : 17)
Query Neighborhood Hits	61	Target Neighborhood Hits	349	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

MBD5_HUMAN
θ value	0.0736092 (rank : 15)	NC score	0.138762 (rank : 10)
Query Neighborhood Hits	61	Target Neighborhood Hits	176	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

CHD4_HUMAN
θ value	0.21417 (rank : 16)	NC score	0.086722 (rank : 22)
Query Neighborhood Hits	61	Target Neighborhood Hits	365	Shared Neighborhood Hits	28
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	0.21417 (rank : 17)	NC score	0.086526 (rank : 23)
Query Neighborhood Hits	61	Target Neighborhood Hits	408	Shared Neighborhood Hits	29
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

AFF4_HUMAN
θ value	0.365318 (rank : 18)	NC score	0.031115 (rank : 36)
Query Neighborhood Hits	61	Target Neighborhood Hits	611	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

SPEG_MOUSE
θ value	0.365318 (rank : 19)	NC score	0.006046 (rank : 57)
Query Neighborhood Hits	61	Target Neighborhood Hits	1959	Shared Neighborhood Hits	12
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ZCPW1_HUMAN
θ value	0.365318 (rank : 20)	NC score	0.098011 (rank : 14)
Query Neighborhood Hits	61	Target Neighborhood Hits	116	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H0M4, Q8NA98, Q9BUD0, Q9NWF7	Gene names	ZCWPW1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1.

NNP1_MOUSE
θ value	0.813845 (rank : 21)	NC score	0.029827 (rank : 38)
Query Neighborhood Hits	61	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	P56183, O35712, Q9ERE1, Q9JI07, Q9JK67, Q9JKU2	Gene names	Nnp1
Domain Architecture
Description	NNP-1 protein (Novel nuclear protein 1) (Nop52).

PF21A_MOUSE
θ value	0.813845 (rank : 22)	NC score	0.090025 (rank : 19)
Query Neighborhood Hits	61	Target Neighborhood Hits	285	Shared Neighborhood Hits	22
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

NSD1_HUMAN
θ value	1.06291 (rank : 23)	NC score	0.075031 (rank : 27)
Query Neighborhood Hits	61	Target Neighborhood Hits	427	Shared Neighborhood Hits	36
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

BAIP2_MOUSE
θ value	1.38821 (rank : 24)	NC score	0.027130 (rank : 40)
Query Neighborhood Hits	61	Target Neighborhood Hits	185	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

HDGF_MOUSE
θ value	1.38821 (rank : 25)	NC score	0.087640 (rank : 20)
Query Neighborhood Hits	61	Target Neighborhood Hits	102	Shared Neighborhood Hits	20
SwissProt Accessions	P51859, Q8BPG7, Q9CYA4, Q9JK87	Gene names	Hdgf, Tdrm1
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF).

PARP2_MOUSE
θ value	1.38821 (rank : 26)	NC score	0.019272 (rank : 44)
Query Neighborhood Hits	61	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	O88554, Q99N29	Gene names	Parp2, Adprt2, Adprtl2, Aspartl2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (mPARP-2).

SP110_HUMAN
θ value	1.38821 (rank : 27)	NC score	0.072355 (rank : 29)
Query Neighborhood Hits	61	Target Neighborhood Hits	141	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

ANK2_HUMAN
θ value	1.81305 (rank : 28)	NC score	0.011288 (rank : 51)
Query Neighborhood Hits	61	Target Neighborhood Hits	1615	Shared Neighborhood Hits	23
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

BAIP2_HUMAN
θ value	1.81305 (rank : 29)	NC score	0.026187 (rank : 41)
Query Neighborhood Hits	61	Target Neighborhood Hits	192	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

DNMT2_HUMAN
θ value	1.81305 (rank : 30)	NC score	0.039539 (rank : 33)
Query Neighborhood Hits	61	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	O14717, O43669	Gene names	DNMT2
Domain Architecture
Description	tRNA (cytosine-5-)-methyltransferase (EC 2.1.1.29) (DNA (cytosine-5)- methyltransferase-like protein 2) (Dnmt2) (DNA methyltransferase homolog HsaIIP) (DNA MTase homolog HsaIIP) (M.HsaIIP) (PuMet).

NPT2B_HUMAN
θ value	1.81305 (rank : 31)	NC score	0.016255 (rank : 46)
Query Neighborhood Hits	61	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	O95436, Q8N2K2, Q8WYA9, Q9P0V7	Gene names	SLC34A2
Domain Architecture	No domain graphic available
Description	Sodium-dependent phosphate transport protein 2B (Sodium/phosphate cotransporter 2B) (Na(+)/Pi cotransporter 2B) (Sodium-phosphate transport protein 2B) (Na(+)-dependent phosphate cotransporter 2B) (NaPi-2b) (Solute carrier family 34 member 2) (NaPi3b).

NSD1_MOUSE
θ value	1.81305 (rank : 32)	NC score	0.055920 (rank : 31)
Query Neighborhood Hits	61	Target Neighborhood Hits	472	Shared Neighborhood Hits	32
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PF21A_HUMAN
θ value	1.81305 (rank : 33)	NC score	0.090088 (rank : 18)
Query Neighborhood Hits	61	Target Neighborhood Hits	303	Shared Neighborhood Hits	23
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

ZMY11_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.086252 (rank : 24)
Query Neighborhood Hits	61	Target Neighborhood Hits	201	Shared Neighborhood Hits	32
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

ZMY11_MOUSE
θ value	1.81305 (rank : 35)	NC score	0.085894 (rank : 25)
Query Neighborhood Hits	61	Target Neighborhood Hits	198	Shared Neighborhood Hits	32
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

DNMT1_MOUSE
θ value	2.36792 (rank : 36)	NC score	0.023509 (rank : 42)
Query Neighborhood Hits	61	Target Neighborhood Hits	137	Shared Neighborhood Hits	5
SwissProt Accessions	P13864, P97413, Q80ZU3, Q9CSC6, Q9QXX6	Gene names	Dnmt1, Dnmt, Met1, Uim
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase MmuI) (DNA MTase MmuI) (MCMT) (M.MmuI) (Met-1).

SPEG_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.004303 (rank : 60)
Query Neighborhood Hits	61	Target Neighborhood Hits	1762	Shared Neighborhood Hits	6
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

AHTF1_MOUSE
θ value	3.0926 (rank : 38)	NC score	0.017336 (rank : 45)
Query Neighborhood Hits	61	Target Neighborhood Hits	176	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CJF7, Q8BVJ5, Q8VD55	Gene names	Ahctf1, Elys
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

HDGR3_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.096735 (rank : 16)
Query Neighborhood Hits	61	Target Neighborhood Hits	60	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y3E1	Gene names	HDGFRP3, HDGF2
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3) (Hepatoma- derived growth factor 2).

HDGR3_MOUSE
θ value	3.0926 (rank : 40)	NC score	0.097251 (rank : 15)
Query Neighborhood Hits	61	Target Neighborhood Hits	42	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JMG7, Q3TRX2, Q8BQ69, Q8BR62, Q9D2M7	Gene names	Hdgfrp3
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3).

SFR11_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.028274 (rank : 39)
Query Neighborhood Hits	61	Target Neighborhood Hits	246	Shared Neighborhood Hits	14
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

ZCPW1_MOUSE
θ value	3.0926 (rank : 42)	NC score	0.073699 (rank : 28)
Query Neighborhood Hits	61	Target Neighborhood Hits	307	Shared Neighborhood Hits	25
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

DJC12_MOUSE
θ value	4.03905 (rank : 43)	NC score	0.030569 (rank : 37)
Query Neighborhood Hits	61	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R022	Gene names	Dnajc12, Jdp1
Domain Architecture
Description	DnaJ homolog subfamily C member 12 (J domain-containing protein 1).

GPX3_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.014326 (rank : 47)
Query Neighborhood Hits	61	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	P22352, O43787, Q86W78, Q9NZ74, Q9UEL1	Gene names	GPX3, GPXP
Domain Architecture
Description	Glutathione peroxidase 3 precursor (EC 1.11.1.9) (GSHPx-3) (GPx-3) (Plasma glutathione peroxidase) (GSHPx-P) (Extracellular glutathione peroxidase) (GPx-P).

NKTR_MOUSE
θ value	4.03905 (rank : 45)	NC score	0.013116 (rank : 48)
Query Neighborhood Hits	61	Target Neighborhood Hits	417	Shared Neighborhood Hits	15
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

FOXD4_MOUSE
θ value	5.27518 (rank : 46)	NC score	0.004513 (rank : 59)
Query Neighborhood Hits	61	Target Neighborhood Hits	98	Shared Neighborhood Hits	4
SwissProt Accessions	Q60688, Q61573	Gene names	Foxd4, Fkh2, Fkhl9, Freac5
Domain Architecture
Description	Forkhead box protein D4 (Forkhead-related protein FKHL9) (Forkhead- related transcription factor 5) (FREAC-5) (Transcription factor FKH- 2).

PSIP1_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.069120 (rank : 30)
Query Neighborhood Hits	61	Target Neighborhood Hits	341	Shared Neighborhood Hits	30
SwissProt Accessions	O75475, O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6	Gene names	PSIP1, DFS70, LEDGF, PSIP2
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) (Dense fine speckles 70 kDa protein) (DFS 70) (CLL-associated antigen KW-7).

PSIP1_MOUSE
θ value	5.27518 (rank : 48)	NC score	0.076486 (rank : 26)
Query Neighborhood Hits	61	Target Neighborhood Hits	313	Shared Neighborhood Hits	29
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

WDHD1_MOUSE
θ value	5.27518 (rank : 49)	NC score	0.007831 (rank : 56)
Query Neighborhood Hits	61	Target Neighborhood Hits	414	Shared Neighborhood Hits	7
SwissProt Accessions	P59328, Q6P408	Gene names	Wdhd1, And1
Domain Architecture	No domain graphic available
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

BPTF_HUMAN
θ value	6.88961 (rank : 50)	NC score	0.036375 (rank : 34)
Query Neighborhood Hits	61	Target Neighborhood Hits	786	Shared Neighborhood Hits	24
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

DEN2A_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.007938 (rank : 55)
Query Neighborhood Hits	61	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULE3, Q1RMD5, Q86XY0	Gene names	DENND2A, KIAA1277
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

F19A2_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.012079 (rank : 50)
Query Neighborhood Hits	61	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N3H0, Q4G0R9, Q68DK0, Q6GTX6	Gene names	FAM19A2, TAFA2
Domain Architecture	No domain graphic available
Description	Protein FAM19A2 precursor (Chemokine-like protein TAFA-2).

F19A2_MOUSE
θ value	6.88961 (rank : 53)	NC score	0.012118 (rank : 49)
Query Neighborhood Hits	61	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TPG7, Q5M9Q3	Gene names	Fam19a2, Tafa2
Domain Architecture	No domain graphic available
Description	Protein FAM19A2 precursor (Chemokine-like protein TAFA-2).

UBP1_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.011220 (rank : 52)
Query Neighborhood Hits	61	Target Neighborhood Hits	259	Shared Neighborhood Hits	7
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

AKAP1_MOUSE
θ value	8.99809 (rank : 55)	NC score	0.009191 (rank : 53)
Query Neighborhood Hits	61	Target Neighborhood Hits	198	Shared Neighborhood Hits	5
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

BAZ1A_HUMAN
θ value	8.99809 (rank : 56)	NC score	0.019936 (rank : 43)
Query Neighborhood Hits	61	Target Neighborhood Hits	693	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BRAP_HUMAN
θ value	8.99809 (rank : 57)	NC score	0.005687 (rank : 58)
Query Neighborhood Hits	61	Target Neighborhood Hits	560	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

DMP1_MOUSE
θ value	8.99809 (rank : 58)	NC score	0.031304 (rank : 35)
Query Neighborhood Hits	61	Target Neighborhood Hits	498	Shared Neighborhood Hits	14
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

MIER1_MOUSE
θ value	8.99809 (rank : 59)	NC score	0.008519 (rank : 54)
Query Neighborhood Hits	61	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q5UAK0, Q5UAK1, Q5UAK2, Q5UAK3, Q6ZPL6, Q9D402	Gene names	Mier1, Kiaa1610
Domain Architecture	No domain graphic available
Description	Mesoderm induction early response protein 1 (Mi-er1).

PKCB1_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.052133 (rank : 32)
Query Neighborhood Hits	61	Target Neighborhood Hits	488	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

TRI13_MOUSE
θ value	8.99809 (rank : 61)	NC score	0.003221 (rank : 61)
Query Neighborhood Hits	61	Target Neighborhood Hits	282	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

Hits sorted by NC score

DNM3B_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	61	Target Neighborhood Hits	61	Shared Neighborhood Hits	61
SwissProt Accessions	O88509, O88510, O88511	Gene names	Dnmt3b
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase MmuIIIB) (DNA MTase MmuIIIB) (M.MmuIIIB).

DNM3B_HUMAN
NC score	0.995391 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	61	Target Neighborhood Hits	59	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UBC3, Q9UBD4, Q9UJQ5, Q9UKA6, Q9UNE5, Q9Y5R9, Q9Y5S0	Gene names	DNMT3B
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase HsaIIIB) (DNA MTase HsaIIIB) (M.HsaIIIB).

DNM3A_MOUSE
NC score	0.976615 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	61	Target Neighborhood Hits	91	Shared Neighborhood Hits	29
SwissProt Accessions	O88508, Q3UH24, Q8CJ60, Q922J0, Q9CSE1	Gene names	Dnmt3a
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA).

DNM3A_HUMAN
NC score	0.973003 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	61	Target Neighborhood Hits	104	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y6K1, Q8WXU9	Gene names	DNMT3A
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA).

DNM3L_HUMAN
NC score	0.913976 (rank : 5)	θ value	6.53529e-67 (rank : 5)
Query Neighborhood Hits	61	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UJW3, Q9BUJ4	Gene names	DNMT3L
Domain Architecture	No domain graphic available
Description	DNA (cytosine-5)-methyltransferase 3-like.

DNM3L_MOUSE
NC score	0.906055 (rank : 6)	θ value	1.6097e-65 (rank : 6)
Query Neighborhood Hits	61	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	Q9CWR8	Gene names	Dnmt3l
Domain Architecture	No domain graphic available
Description	DNA (cytosine-5)-methyltransferase 3-like.

PWWP2_HUMAN
NC score	0.461210 (rank : 7)	θ value	3.64472e-09 (rank : 7)
Query Neighborhood Hits	61	Target Neighborhood Hits	80	Shared Neighborhood Hits	21
SwissProt Accessions	Q6NUJ5, Q5SZI0, Q6ZQX5, Q96F43	Gene names	PWWP2
Domain Architecture	No domain graphic available
Description	PWWP domain-containing protein 2.

ATRX_MOUSE
NC score	0.191503 (rank : 8)	θ value	7.59969e-07 (rank : 9)
Query Neighborhood Hits	61	Target Neighborhood Hits	682	Shared Neighborhood Hits	32
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

ATRX_HUMAN
NC score	0.188307 (rank : 9)	θ value	1.53129e-07 (rank : 8)
Query Neighborhood Hits	61	Target Neighborhood Hits	842	Shared Neighborhood Hits	31
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

MBD5_HUMAN
NC score	0.138762 (rank : 10)	θ value	0.0736092 (rank : 15)
Query Neighborhood Hits	61	Target Neighborhood Hits	176	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

MSH6_MOUSE
NC score	0.117777 (rank : 11)	θ value	0.0252991 (rank : 11)
Query Neighborhood Hits	61	Target Neighborhood Hits	55	Shared Neighborhood Hits	21
SwissProt Accessions	P54276, O54710	Gene names	Msh6, Gtmbp
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

MSH6_HUMAN
NC score	0.110759 (rank : 12)	θ value	0.0193708 (rank : 10)
Query Neighborhood Hits	61	Target Neighborhood Hits	81	Shared Neighborhood Hits	22
SwissProt Accessions	P52701, O43706, O43917, Q8TCX4, Q9BTB5	Gene names	MSH6, GTBP
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

HDGF_HUMAN
NC score	0.104382 (rank : 13)	θ value	0.0431538 (rank : 12)
Query Neighborhood Hits	61	Target Neighborhood Hits	61	Shared Neighborhood Hits	18
SwissProt Accessions	P51858, Q5SZ09	Gene names	HDGF, HMG1L2
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF) (High-mobility group protein 1- like 2) (HMG-1L2).

ZCPW1_HUMAN
NC score	0.098011 (rank : 14)	θ value	0.365318 (rank : 20)
Query Neighborhood Hits	61	Target Neighborhood Hits	116	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H0M4, Q8NA98, Q9BUD0, Q9NWF7	Gene names	ZCWPW1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1.

HDGR3_MOUSE
NC score	0.097251 (rank : 15)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	61	Target Neighborhood Hits	42	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JMG7, Q3TRX2, Q8BQ69, Q8BR62, Q9D2M7	Gene names	Hdgfrp3
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3).

HDGR3_HUMAN
NC score	0.096735 (rank : 16)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	61	Target Neighborhood Hits	60	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y3E1	Gene names	HDGFRP3, HDGF2
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3) (Hepatoma- derived growth factor 2).

CHD5_HUMAN
NC score	0.091330 (rank : 17)	θ value	0.0736092 (rank : 14)
Query Neighborhood Hits	61	Target Neighborhood Hits	349	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

PF21A_HUMAN
NC score	0.090088 (rank : 18)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	61	Target Neighborhood Hits	303	Shared Neighborhood Hits	23
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
NC score	0.090025 (rank : 19)	θ value	0.813845 (rank : 22)
Query Neighborhood Hits	61	Target Neighborhood Hits	285	Shared Neighborhood Hits	22
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

HDGF_MOUSE
NC score	0.087640 (rank : 20)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	61	Target Neighborhood Hits	102	Shared Neighborhood Hits	20
SwissProt Accessions	P51859, Q8BPG7, Q9CYA4, Q9JK87	Gene names	Hdgf, Tdrm1
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF).

CHD3_HUMAN
NC score	0.087228 (rank : 21)	θ value	0.0736092 (rank : 13)
Query Neighborhood Hits	61	Target Neighborhood Hits	397	Shared Neighborhood Hits	25
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD4_HUMAN
NC score	0.086722 (rank : 22)	θ value	0.21417 (rank : 16)
Query Neighborhood Hits	61	Target Neighborhood Hits	365	Shared Neighborhood Hits	28
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
NC score	0.086526 (rank : 23)	θ value	0.21417 (rank : 17)
Query Neighborhood Hits	61	Target Neighborhood Hits	408	Shared Neighborhood Hits	29
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

ZMY11_HUMAN
NC score	0.086252 (rank : 24)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	61	Target Neighborhood Hits	201	Shared Neighborhood Hits	32
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

ZMY11_MOUSE
NC score	0.085894 (rank : 25)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	61	Target Neighborhood Hits	198	Shared Neighborhood Hits	32
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

PSIP1_MOUSE
NC score	0.076486 (rank : 26)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	61	Target Neighborhood Hits	313	Shared Neighborhood Hits	29
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

NSD1_HUMAN
NC score	0.075031 (rank : 27)	θ value	1.06291 (rank : 23)
Query Neighborhood Hits	61	Target Neighborhood Hits	427	Shared Neighborhood Hits	36
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

ZCPW1_MOUSE
NC score	0.073699 (rank : 28)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	61	Target Neighborhood Hits	307	Shared Neighborhood Hits	25
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

SP110_HUMAN
NC score	0.072355 (rank : 29)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	61	Target Neighborhood Hits	141	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

PSIP1_HUMAN
NC score	0.069120 (rank : 30)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	61	Target Neighborhood Hits	341	Shared Neighborhood Hits	30
SwissProt Accessions	O75475, O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6	Gene names	PSIP1, DFS70, LEDGF, PSIP2
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) (Dense fine speckles 70 kDa protein) (DFS 70) (CLL-associated antigen KW-7).

NSD1_MOUSE
NC score	0.055920 (rank : 31)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	61	Target Neighborhood Hits	472	Shared Neighborhood Hits	32
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PKCB1_HUMAN
NC score	0.052133 (rank : 32)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	61	Target Neighborhood Hits	488	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

DNMT2_HUMAN
NC score	0.039539 (rank : 33)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	61	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	O14717, O43669	Gene names	DNMT2
Domain Architecture
Description	tRNA (cytosine-5-)-methyltransferase (EC 2.1.1.29) (DNA (cytosine-5)- methyltransferase-like protein 2) (Dnmt2) (DNA methyltransferase homolog HsaIIP) (DNA MTase homolog HsaIIP) (M.HsaIIP) (PuMet).

BPTF_HUMAN
NC score	0.036375 (rank : 34)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	61	Target Neighborhood Hits	786	Shared Neighborhood Hits	24
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

DMP1_MOUSE
NC score	0.031304 (rank : 35)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	61	Target Neighborhood Hits	498	Shared Neighborhood Hits	14
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

AFF4_HUMAN
NC score	0.031115 (rank : 36)	θ value	0.365318 (rank : 18)
Query Neighborhood Hits	61	Target Neighborhood Hits	611	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

DJC12_MOUSE
NC score	0.030569 (rank : 37)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	61	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R022	Gene names	Dnajc12, Jdp1
Domain Architecture
Description	DnaJ homolog subfamily C member 12 (J domain-containing protein 1).

NNP1_MOUSE
NC score	0.029827 (rank : 38)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	61	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	P56183, O35712, Q9ERE1, Q9JI07, Q9JK67, Q9JKU2	Gene names	Nnp1
Domain Architecture
Description	NNP-1 protein (Novel nuclear protein 1) (Nop52).

SFR11_HUMAN
NC score	0.028274 (rank : 39)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	61	Target Neighborhood Hits	246	Shared Neighborhood Hits	14
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

BAIP2_MOUSE
NC score	0.027130 (rank : 40)	θ value	1.38821 (rank : 24)
Query Neighborhood Hits	61	Target Neighborhood Hits	185	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

BAIP2_HUMAN
NC score	0.026187 (rank : 41)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	61	Target Neighborhood Hits	192	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

DNMT1_MOUSE
NC score	0.023509 (rank : 42)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	61	Target Neighborhood Hits	137	Shared Neighborhood Hits	5
SwissProt Accessions	P13864, P97413, Q80ZU3, Q9CSC6, Q9QXX6	Gene names	Dnmt1, Dnmt, Met1, Uim
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase MmuI) (DNA MTase MmuI) (MCMT) (M.MmuI) (Met-1).

BAZ1A_HUMAN
NC score	0.019936 (rank : 43)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	61	Target Neighborhood Hits	693	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

PARP2_MOUSE
NC score	0.019272 (rank : 44)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	61	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	O88554, Q99N29	Gene names	Parp2, Adprt2, Adprtl2, Aspartl2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (mPARP-2).

AHTF1_MOUSE
NC score	0.017336 (rank : 45)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	61	Target Neighborhood Hits	176	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CJF7, Q8BVJ5, Q8VD55	Gene names	Ahctf1, Elys
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

NPT2B_HUMAN
NC score	0.016255 (rank : 46)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	61	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	O95436, Q8N2K2, Q8WYA9, Q9P0V7	Gene names	SLC34A2
Domain Architecture	No domain graphic available
Description	Sodium-dependent phosphate transport protein 2B (Sodium/phosphate cotransporter 2B) (Na(+)/Pi cotransporter 2B) (Sodium-phosphate transport protein 2B) (Na(+)-dependent phosphate cotransporter 2B) (NaPi-2b) (Solute carrier family 34 member 2) (NaPi3b).

GPX3_HUMAN
NC score	0.014326 (rank : 47)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	61	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	P22352, O43787, Q86W78, Q9NZ74, Q9UEL1	Gene names	GPX3, GPXP
Domain Architecture
Description	Glutathione peroxidase 3 precursor (EC 1.11.1.9) (GSHPx-3) (GPx-3) (Plasma glutathione peroxidase) (GSHPx-P) (Extracellular glutathione peroxidase) (GPx-P).

NKTR_MOUSE
NC score	0.013116 (rank : 48)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	61	Target Neighborhood Hits	417	Shared Neighborhood Hits	15
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

F19A2_MOUSE
NC score	0.012118 (rank : 49)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	61	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TPG7, Q5M9Q3	Gene names	Fam19a2, Tafa2
Domain Architecture	No domain graphic available
Description	Protein FAM19A2 precursor (Chemokine-like protein TAFA-2).

F19A2_HUMAN
NC score	0.012079 (rank : 50)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	61	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N3H0, Q4G0R9, Q68DK0, Q6GTX6	Gene names	FAM19A2, TAFA2
Domain Architecture	No domain graphic available
Description	Protein FAM19A2 precursor (Chemokine-like protein TAFA-2).

ANK2_HUMAN
NC score	0.011288 (rank : 51)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	61	Target Neighborhood Hits	1615	Shared Neighborhood Hits	23
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

UBP1_HUMAN
NC score	0.011220 (rank : 52)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	61	Target Neighborhood Hits	259	Shared Neighborhood Hits	7
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

AKAP1_MOUSE
NC score	0.009191 (rank : 53)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	61	Target Neighborhood Hits	198	Shared Neighborhood Hits	5
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

MIER1_MOUSE
NC score	0.008519 (rank : 54)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	61	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q5UAK0, Q5UAK1, Q5UAK2, Q5UAK3, Q6ZPL6, Q9D402	Gene names	Mier1, Kiaa1610
Domain Architecture	No domain graphic available
Description	Mesoderm induction early response protein 1 (Mi-er1).

DEN2A_HUMAN
NC score	0.007938 (rank : 55)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	61	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULE3, Q1RMD5, Q86XY0	Gene names	DENND2A, KIAA1277
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

WDHD1_MOUSE
NC score	0.007831 (rank : 56)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	61	Target Neighborhood Hits	414	Shared Neighborhood Hits	7
SwissProt Accessions	P59328, Q6P408	Gene names	Wdhd1, And1
Domain Architecture	No domain graphic available
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

SPEG_MOUSE
NC score	0.006046 (rank : 57)	θ value	0.365318 (rank : 19)
Query Neighborhood Hits	61	Target Neighborhood Hits	1959	Shared Neighborhood Hits	12
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

BRAP_HUMAN
NC score	0.005687 (rank : 58)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	61	Target Neighborhood Hits	560	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

FOXD4_MOUSE
NC score	0.004513 (rank : 59)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	61	Target Neighborhood Hits	98	Shared Neighborhood Hits	4
SwissProt Accessions	Q60688, Q61573	Gene names	Foxd4, Fkh2, Fkhl9, Freac5
Domain Architecture
Description	Forkhead box protein D4 (Forkhead-related protein FKHL9) (Forkhead- related transcription factor 5) (FREAC-5) (Transcription factor FKH- 2).

SPEG_HUMAN
NC score	0.004303 (rank : 60)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	61	Target Neighborhood Hits	1762	Shared Neighborhood Hits	6
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TRI13_MOUSE
NC score	0.003221 (rank : 61)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	61	Target Neighborhood Hits	282	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).