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Network neighborhood for query Sequence : PWWP2_HUMAN

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PWWP2_HUMAN
SwissProt Accessions	Q6NUJ5, Q5SZI0, Q6ZQX5, Q96F43	Gene names	PWWP2
Domain Architecture	No domain graphic available
Description	PWWP domain-containing protein 2.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PWWP2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	80	Target Neighborhood Hits	80	Shared Neighborhood Hits	80
SwissProt Accessions	Q6NUJ5, Q5SZI0, Q6ZQX5, Q96F43	Gene names	PWWP2
Domain Architecture	No domain graphic available
Description	PWWP domain-containing protein 2.

DNM3A_HUMAN
θ value	1.133e-10 (rank : 2)	NC score	0.467719 (rank : 2)
Query Neighborhood Hits	80	Target Neighborhood Hits	104	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y6K1, Q8WXU9	Gene names	DNMT3A
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA).

DNM3A_MOUSE
θ value	1.133e-10 (rank : 3)	NC score	0.466598 (rank : 3)
Query Neighborhood Hits	80	Target Neighborhood Hits	91	Shared Neighborhood Hits	20
SwissProt Accessions	O88508, Q3UH24, Q8CJ60, Q922J0, Q9CSE1	Gene names	Dnmt3a
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA).

DNM3B_HUMAN
θ value	2.13673e-09 (rank : 4)	NC score	0.463424 (rank : 4)
Query Neighborhood Hits	80	Target Neighborhood Hits	59	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UBC3, Q9UBD4, Q9UJQ5, Q9UKA6, Q9UNE5, Q9Y5R9, Q9Y5S0	Gene names	DNMT3B
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase HsaIIIB) (DNA MTase HsaIIIB) (M.HsaIIIB).

DNM3B_MOUSE
θ value	3.64472e-09 (rank : 5)	NC score	0.461210 (rank : 5)
Query Neighborhood Hits	80	Target Neighborhood Hits	61	Shared Neighborhood Hits	21
SwissProt Accessions	O88509, O88510, O88511	Gene names	Dnmt3b
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase MmuIIIB) (DNA MTase MmuIIIB) (M.MmuIIIB).

PSIP1_HUMAN
θ value	0.000121331 (rank : 6)	NC score	0.319844 (rank : 11)
Query Neighborhood Hits	80	Target Neighborhood Hits	341	Shared Neighborhood Hits	27
SwissProt Accessions	O75475, O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6	Gene names	PSIP1, DFS70, LEDGF, PSIP2
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) (Dense fine speckles 70 kDa protein) (DFS 70) (CLL-associated antigen KW-7).

HDGR3_HUMAN
θ value	0.000158464 (rank : 7)	NC score	0.374703 (rank : 7)
Query Neighborhood Hits	80	Target Neighborhood Hits	60	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y3E1	Gene names	HDGFRP3, HDGF2
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3) (Hepatoma- derived growth factor 2).

HDGR3_MOUSE
θ value	0.000158464 (rank : 8)	NC score	0.375835 (rank : 6)
Query Neighborhood Hits	80	Target Neighborhood Hits	42	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JMG7, Q3TRX2, Q8BQ69, Q8BR62, Q9D2M7	Gene names	Hdgfrp3
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3).

PSIP1_MOUSE
θ value	0.000158464 (rank : 9)	NC score	0.328047 (rank : 10)
Query Neighborhood Hits	80	Target Neighborhood Hits	313	Shared Neighborhood Hits	28
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

MSH6_MOUSE
θ value	0.00228821 (rank : 10)	NC score	0.203315 (rank : 16)
Query Neighborhood Hits	80	Target Neighborhood Hits	55	Shared Neighborhood Hits	20
SwissProt Accessions	P54276, O54710	Gene names	Msh6, Gtmbp
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

TARA_MOUSE
θ value	0.00509761 (rank : 11)	NC score	0.073832 (rank : 26)
Query Neighborhood Hits	80	Target Neighborhood Hits	1133	Shared Neighborhood Hits	20
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

HDGF_HUMAN
θ value	0.00869519 (rank : 12)	NC score	0.347747 (rank : 8)
Query Neighborhood Hits	80	Target Neighborhood Hits	61	Shared Neighborhood Hits	20
SwissProt Accessions	P51858, Q5SZ09	Gene names	HDGF, HMG1L2
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF) (High-mobility group protein 1- like 2) (HMG-1L2).

HDGF_MOUSE
θ value	0.00869519 (rank : 13)	NC score	0.335397 (rank : 9)
Query Neighborhood Hits	80	Target Neighborhood Hits	102	Shared Neighborhood Hits	21
SwissProt Accessions	P51859, Q8BPG7, Q9CYA4, Q9JK87	Gene names	Hdgf, Tdrm1
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF).

MSH6_HUMAN
θ value	0.0113563 (rank : 14)	NC score	0.195746 (rank : 17)
Query Neighborhood Hits	80	Target Neighborhood Hits	81	Shared Neighborhood Hits	21
SwissProt Accessions	P52701, O43706, O43917, Q8TCX4, Q9BTB5	Gene names	MSH6, GTBP
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

ZCPW1_MOUSE
θ value	0.0193708 (rank : 15)	NC score	0.205481 (rank : 15)
Query Neighborhood Hits	80	Target Neighborhood Hits	307	Shared Neighborhood Hits	27
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

JPH2_HUMAN
θ value	0.0252991 (rank : 16)	NC score	0.063463 (rank : 28)
Query Neighborhood Hits	80	Target Neighborhood Hits	639	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

RGS3_MOUSE
θ value	0.0736092 (rank : 17)	NC score	0.054524 (rank : 32)
Query Neighborhood Hits	80	Target Neighborhood Hits	1621	Shared Neighborhood Hits	35
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

NFH_MOUSE
θ value	0.0961366 (rank : 18)	NC score	0.047610 (rank : 41)
Query Neighborhood Hits	80	Target Neighborhood Hits	2247	Shared Neighborhood Hits	42
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NSD1_HUMAN
θ value	0.0961366 (rank : 19)	NC score	0.127338 (rank : 19)
Query Neighborhood Hits	80	Target Neighborhood Hits	427	Shared Neighborhood Hits	28
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

GLI2_HUMAN
θ value	0.125558 (rank : 20)	NC score	0.012922 (rank : 76)
Query Neighborhood Hits	80	Target Neighborhood Hits	971	Shared Neighborhood Hits	9
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

TAF1C_MOUSE
θ value	0.125558 (rank : 21)	NC score	0.080909 (rank : 24)
Query Neighborhood Hits	80	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PDZ2, P97359, Q3U3B6, Q8BN54	Gene names	Taf1c
Domain Architecture	No domain graphic available
Description	TATA box-binding protein-associated factor, RNA polymerase I, subunit C (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (TBP-associated factor RNA polymerase I 95 kDa) (TAFI95).

ZCPW1_HUMAN
θ value	0.163984 (rank : 22)	NC score	0.210265 (rank : 14)
Query Neighborhood Hits	80	Target Neighborhood Hits	116	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H0M4, Q8NA98, Q9BUD0, Q9NWF7	Gene names	ZCWPW1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1.

MBD5_HUMAN
θ value	0.279714 (rank : 23)	NC score	0.138878 (rank : 18)
Query Neighborhood Hits	80	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

PKCB1_HUMAN
θ value	0.279714 (rank : 24)	NC score	0.123967 (rank : 22)
Query Neighborhood Hits	80	Target Neighborhood Hits	488	Shared Neighborhood Hits	30
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

SC24C_HUMAN
θ value	0.279714 (rank : 25)	NC score	0.051240 (rank : 34)
Query Neighborhood Hits	80	Target Neighborhood Hits	662	Shared Neighborhood Hits	18
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

DDX51_HUMAN
θ value	0.365318 (rank : 26)	NC score	0.029501 (rank : 54)
Query Neighborhood Hits	80	Target Neighborhood Hits	332	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

SH3K1_HUMAN
θ value	0.365318 (rank : 27)	NC score	0.050009 (rank : 35)
Query Neighborhood Hits	80	Target Neighborhood Hits	341	Shared Neighborhood Hits	9
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

NSD1_MOUSE
θ value	0.47712 (rank : 28)	NC score	0.104737 (rank : 23)
Query Neighborhood Hits	80	Target Neighborhood Hits	472	Shared Neighborhood Hits	29
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

SET1A_HUMAN
θ value	0.62314 (rank : 29)	NC score	0.075227 (rank : 25)
Query Neighborhood Hits	80	Target Neighborhood Hits	690	Shared Neighborhood Hits	25
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

TXND2_HUMAN
θ value	0.62314 (rank : 30)	NC score	0.067233 (rank : 27)
Query Neighborhood Hits	80	Target Neighborhood Hits	793	Shared Neighborhood Hits	29
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

IF2B2_HUMAN
θ value	0.813845 (rank : 31)	NC score	0.037389 (rank : 45)
Query Neighborhood Hits	80	Target Neighborhood Hits	142	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6M1	Gene names	IGF2BP2, IMP2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62).

IF4G3_MOUSE
θ value	0.813845 (rank : 32)	NC score	0.049154 (rank : 37)
Query Neighborhood Hits	80	Target Neighborhood Hits	279	Shared Neighborhood Hits	11
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

PGCA_MOUSE
θ value	0.813845 (rank : 33)	NC score	0.027066 (rank : 56)
Query Neighborhood Hits	80	Target Neighborhood Hits	643	Shared Neighborhood Hits	13
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

RABX5_HUMAN
θ value	0.813845 (rank : 34)	NC score	0.048177 (rank : 39)
Query Neighborhood Hits	80	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJ41	Gene names	RABGEF1, RABEX5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5) (Rabaptin-5-associated exchange factor for Rab5).

XRCC1_MOUSE
θ value	0.813845 (rank : 35)	NC score	0.060504 (rank : 30)
Query Neighborhood Hits	80	Target Neighborhood Hits	242	Shared Neighborhood Hits	10
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

BLNK_MOUSE
θ value	1.06291 (rank : 36)	NC score	0.049575 (rank : 36)
Query Neighborhood Hits	80	Target Neighborhood Hits	296	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

SH3K1_MOUSE
θ value	1.06291 (rank : 37)	NC score	0.045859 (rank : 42)
Query Neighborhood Hits	80	Target Neighborhood Hits	332	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

TITIN_HUMAN
θ value	1.06291 (rank : 38)	NC score	0.017444 (rank : 70)
Query Neighborhood Hits	80	Target Neighborhood Hits	2923	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ADA19_HUMAN
θ value	1.38821 (rank : 39)	NC score	0.014104 (rank : 74)
Query Neighborhood Hits	80	Target Neighborhood Hits	381	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ANR11_HUMAN
θ value	1.38821 (rank : 40)	NC score	0.030298 (rank : 51)
Query Neighborhood Hits	80	Target Neighborhood Hits	1289	Shared Neighborhood Hits	20
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

SIVA_HUMAN
θ value	1.38821 (rank : 41)	NC score	0.057558 (rank : 31)
Query Neighborhood Hits	80	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	O15304, Q96P98, Q9UPD6	Gene names	SIVA
Domain Architecture
Description	Apoptosis regulatory protein Siva (CD27-binding protein) (CD27BP).

SOX13_MOUSE
θ value	1.38821 (rank : 42)	NC score	0.026123 (rank : 60)
Query Neighborhood Hits	80	Target Neighborhood Hits	495	Shared Neighborhood Hits	11
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

ZMY11_HUMAN
θ value	1.38821 (rank : 43)	NC score	0.124808 (rank : 21)
Query Neighborhood Hits	80	Target Neighborhood Hits	201	Shared Neighborhood Hits	21
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

ZMY11_MOUSE
θ value	1.38821 (rank : 44)	NC score	0.125490 (rank : 20)
Query Neighborhood Hits	80	Target Neighborhood Hits	198	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

CS007_MOUSE
θ value	1.81305 (rank : 45)	NC score	0.048878 (rank : 38)
Query Neighborhood Hits	80	Target Neighborhood Hits	464	Shared Neighborhood Hits	21
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

JHD2B_HUMAN
θ value	1.81305 (rank : 46)	NC score	0.026361 (rank : 58)
Query Neighborhood Hits	80	Target Neighborhood Hits	171	Shared Neighborhood Hits	6
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

PUNC_MOUSE
θ value	1.81305 (rank : 47)	NC score	0.017622 (rank : 69)
Query Neighborhood Hits	80	Target Neighborhood Hits	501	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

ROBO4_MOUSE
θ value	1.81305 (rank : 48)	NC score	0.026605 (rank : 57)
Query Neighborhood Hits	80	Target Neighborhood Hits	358	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

UBP51_HUMAN
θ value	1.81305 (rank : 49)	NC score	0.019895 (rank : 63)
Query Neighborhood Hits	80	Target Neighborhood Hits	162	Shared Neighborhood Hits	6
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

GP176_MOUSE
θ value	2.36792 (rank : 50)	NC score	0.011793 (rank : 77)
Query Neighborhood Hits	80	Target Neighborhood Hits	539	Shared Neighborhood Hits	3
SwissProt Accessions	Q80WT4, Q80UC4	Gene names	Gpr176, Agr9, Gm1012
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 176 (G-protein coupled receptor AGR9).

RFX3_HUMAN
θ value	2.36792 (rank : 51)	NC score	0.023822 (rank : 61)
Query Neighborhood Hits	80	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	P48380, Q5JTL7, Q5JTL8, Q6NW13, Q8WTU4, Q95HL5, Q95HL6	Gene names	RFX3
Domain Architecture
Description	Transcription factor RFX3.

TF65_HUMAN
θ value	2.36792 (rank : 52)	NC score	0.026133 (rank : 59)
Query Neighborhood Hits	80	Target Neighborhood Hits	115	Shared Neighborhood Hits	7
SwissProt Accessions	Q04206, Q6SLK1	Gene names	RELA, NFKB3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

ATN1_HUMAN
θ value	3.0926 (rank : 53)	NC score	0.048001 (rank : 40)
Query Neighborhood Hits	80	Target Neighborhood Hits	676	Shared Neighborhood Hits	23
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

NOP56_HUMAN
θ value	3.0926 (rank : 54)	NC score	0.033480 (rank : 47)
Query Neighborhood Hits	80	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	O00567, Q9NQ05	Gene names	NOL5A, NOP56
Domain Architecture
Description	Nucleolar protein Nop56 (Nucleolar protein 5A).

REPS2_HUMAN
θ value	3.0926 (rank : 55)	NC score	0.033994 (rank : 46)
Query Neighborhood Hits	80	Target Neighborhood Hits	131	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NFH8, O43428, Q8NFI5	Gene names	REPS2, POB1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

BRE1B_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.010531 (rank : 79)
Query Neighborhood Hits	80	Target Neighborhood Hits	1040	Shared Neighborhood Hits	7
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

JIP3_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.017753 (rank : 68)
Query Neighborhood Hits	80	Target Neighborhood Hits	1039	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

TENA_MOUSE
θ value	4.03905 (rank : 58)	NC score	0.010214 (rank : 80)
Query Neighborhood Hits	80	Target Neighborhood Hits	596	Shared Neighborhood Hits	6
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

ULK1_MOUSE
θ value	4.03905 (rank : 59)	NC score	0.003429 (rank : 83)
Query Neighborhood Hits	80	Target Neighborhood Hits	1214	Shared Neighborhood Hits	17
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

DCX_HUMAN
θ value	5.27518 (rank : 60)	NC score	0.018429 (rank : 65)
Query Neighborhood Hits	80	Target Neighborhood Hits	141	Shared Neighborhood Hits	9
SwissProt Accessions	O43602, O43911	Gene names	DCX, DBCN, LISX
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

PDLI4_HUMAN
θ value	5.27518 (rank : 61)	NC score	0.015143 (rank : 73)
Query Neighborhood Hits	80	Target Neighborhood Hits	245	Shared Neighborhood Hits	3
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

RT35_MOUSE
θ value	5.27518 (rank : 62)	NC score	0.029781 (rank : 53)
Query Neighborhood Hits	80	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BJZ4, Q8VCG7	Gene names	Mrps35
Domain Architecture	No domain graphic available
Description	28S ribosomal protein S35, mitochondrial precursor (S35mt) (MRP-S35).

SASH1_MOUSE
θ value	5.27518 (rank : 63)	NC score	0.030352 (rank : 50)
Query Neighborhood Hits	80	Target Neighborhood Hits	263	Shared Neighborhood Hits	14
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

T22D4_HUMAN
θ value	5.27518 (rank : 64)	NC score	0.028948 (rank : 55)
Query Neighborhood Hits	80	Target Neighborhood Hits	403	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

ZN318_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.030856 (rank : 49)
Query Neighborhood Hits	80	Target Neighborhood Hits	497	Shared Neighborhood Hits	11
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

ADCY9_HUMAN
θ value	6.88961 (rank : 66)	NC score	0.010851 (rank : 78)
Query Neighborhood Hits	80	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	O60503, O60273, Q4ZHT9, Q4ZIR5, Q9BWT4, Q9UGP2	Gene names	ADCY9, KIAA0520
Domain Architecture
Description	Adenylate cyclase type 9 (EC 4.6.1.1) (Adenylate cyclase type IX) (ATP pyrophosphate-lyase 9) (Adenylyl cyclase 9).

ETV3_HUMAN
θ value	6.88961 (rank : 67)	NC score	0.018313 (rank : 66)
Query Neighborhood Hits	80	Target Neighborhood Hits	312	Shared Neighborhood Hits	14
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

FZD6_MOUSE
θ value	6.88961 (rank : 68)	NC score	0.007955 (rank : 82)
Query Neighborhood Hits	80	Target Neighborhood Hits	135	Shared Neighborhood Hits	2
SwissProt Accessions	Q61089	Gene names	Fzd6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (mFz6).

MDC1_HUMAN
θ value	6.88961 (rank : 69)	NC score	0.041027 (rank : 44)
Query Neighborhood Hits	80	Target Neighborhood Hits	1446	Shared Neighborhood Hits	33
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

VGFR3_MOUSE
θ value	6.88961 (rank : 70)	NC score	0.002890 (rank : 84)
Query Neighborhood Hits	80	Target Neighborhood Hits	1056	Shared Neighborhood Hits	7
SwissProt Accessions	P35917	Gene names	Flt4, Flt-4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

CBP_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.029976 (rank : 52)
Query Neighborhood Hits	80	Target Neighborhood Hits	941	Shared Neighborhood Hits	28
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CEL_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.014091 (rank : 75)
Query Neighborhood Hits	80	Target Neighborhood Hits	896	Shared Neighborhood Hits	20
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CS029_MOUSE
θ value	8.99809 (rank : 73)	NC score	0.020348 (rank : 62)
Query Neighborhood Hits	80	Target Neighborhood Hits	201	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CS00	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 homolog.

ELL_HUMAN
θ value	8.99809 (rank : 74)	NC score	0.016789 (rank : 71)
Query Neighborhood Hits	80	Target Neighborhood Hits	183	Shared Neighborhood Hits	4
SwissProt Accessions	P55199	Gene names	ELL, C19orf17
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

IF4G1_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.041709 (rank : 43)
Query Neighborhood Hits	80	Target Neighborhood Hits	347	Shared Neighborhood Hits	17
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

PCLO_MOUSE
θ value	8.99809 (rank : 76)	NC score	0.031500 (rank : 48)
Query Neighborhood Hits	80	Target Neighborhood Hits	2275	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PTN23_HUMAN
θ value	8.99809 (rank : 77)	NC score	0.018520 (rank : 64)
Query Neighborhood Hits	80	Target Neighborhood Hits	646	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

RIMB1_MOUSE
θ value	8.99809 (rank : 78)	NC score	0.017838 (rank : 67)
Query Neighborhood Hits	80	Target Neighborhood Hits	1376	Shared Neighborhood Hits	22
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

TENX_HUMAN
θ value	8.99809 (rank : 79)	NC score	0.009399 (rank : 81)
Query Neighborhood Hits	80	Target Neighborhood Hits	789	Shared Neighborhood Hits	8
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

ZN533_MOUSE
θ value	8.99809 (rank : 80)	NC score	0.016478 (rank : 72)
Query Neighborhood Hits	80	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BXJ8, Q8BWQ7	Gene names	Znf533, Zfp533
Domain Architecture	No domain graphic available
Description	Zinc finger protein 533.

ATRX_MOUSE
θ value	θ > 10 (rank : 81)	NC score	0.054093 (rank : 33)
Query Neighborhood Hits	80	Target Neighborhood Hits	682	Shared Neighborhood Hits	21
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

DNM3L_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.281135 (rank : 12)
Query Neighborhood Hits	80	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJW3, Q9BUJ4	Gene names	DNMT3L
Domain Architecture	No domain graphic available
Description	DNA (cytosine-5)-methyltransferase 3-like.

DNM3L_MOUSE
θ value	θ > 10 (rank : 83)	NC score	0.277762 (rank : 13)
Query Neighborhood Hits	80	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CWR8	Gene names	Dnmt3l
Domain Architecture	No domain graphic available
Description	DNA (cytosine-5)-methyltransferase 3-like.

TMAP1_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.062030 (rank : 29)
Query Neighborhood Hits	80	Target Neighborhood Hits	140	Shared Neighborhood Hits	10
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

Hits sorted by NC score

PWWP2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	80	Target Neighborhood Hits	80	Shared Neighborhood Hits	80
SwissProt Accessions	Q6NUJ5, Q5SZI0, Q6ZQX5, Q96F43	Gene names	PWWP2
Domain Architecture	No domain graphic available
Description	PWWP domain-containing protein 2.

DNM3A_HUMAN
NC score	0.467719 (rank : 2)	θ value	1.133e-10 (rank : 2)
Query Neighborhood Hits	80	Target Neighborhood Hits	104	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y6K1, Q8WXU9	Gene names	DNMT3A
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA).

DNM3A_MOUSE
NC score	0.466598 (rank : 3)	θ value	1.133e-10 (rank : 3)
Query Neighborhood Hits	80	Target Neighborhood Hits	91	Shared Neighborhood Hits	20
SwissProt Accessions	O88508, Q3UH24, Q8CJ60, Q922J0, Q9CSE1	Gene names	Dnmt3a
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA).

DNM3B_HUMAN
NC score	0.463424 (rank : 4)	θ value	2.13673e-09 (rank : 4)
Query Neighborhood Hits	80	Target Neighborhood Hits	59	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UBC3, Q9UBD4, Q9UJQ5, Q9UKA6, Q9UNE5, Q9Y5R9, Q9Y5S0	Gene names	DNMT3B
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase HsaIIIB) (DNA MTase HsaIIIB) (M.HsaIIIB).

DNM3B_MOUSE
NC score	0.461210 (rank : 5)	θ value	3.64472e-09 (rank : 5)
Query Neighborhood Hits	80	Target Neighborhood Hits	61	Shared Neighborhood Hits	21
SwissProt Accessions	O88509, O88510, O88511	Gene names	Dnmt3b
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase MmuIIIB) (DNA MTase MmuIIIB) (M.MmuIIIB).

HDGR3_MOUSE
NC score	0.375835 (rank : 6)	θ value	0.000158464 (rank : 8)
Query Neighborhood Hits	80	Target Neighborhood Hits	42	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JMG7, Q3TRX2, Q8BQ69, Q8BR62, Q9D2M7	Gene names	Hdgfrp3
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3).

HDGR3_HUMAN
NC score	0.374703 (rank : 7)	θ value	0.000158464 (rank : 7)
Query Neighborhood Hits	80	Target Neighborhood Hits	60	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y3E1	Gene names	HDGFRP3, HDGF2
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3) (Hepatoma- derived growth factor 2).

HDGF_HUMAN
NC score	0.347747 (rank : 8)	θ value	0.00869519 (rank : 12)
Query Neighborhood Hits	80	Target Neighborhood Hits	61	Shared Neighborhood Hits	20
SwissProt Accessions	P51858, Q5SZ09	Gene names	HDGF, HMG1L2
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF) (High-mobility group protein 1- like 2) (HMG-1L2).

HDGF_MOUSE
NC score	0.335397 (rank : 9)	θ value	0.00869519 (rank : 13)
Query Neighborhood Hits	80	Target Neighborhood Hits	102	Shared Neighborhood Hits	21
SwissProt Accessions	P51859, Q8BPG7, Q9CYA4, Q9JK87	Gene names	Hdgf, Tdrm1
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF).

PSIP1_MOUSE
NC score	0.328047 (rank : 10)	θ value	0.000158464 (rank : 9)
Query Neighborhood Hits	80	Target Neighborhood Hits	313	Shared Neighborhood Hits	28
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

PSIP1_HUMAN
NC score	0.319844 (rank : 11)	θ value	0.000121331 (rank : 6)
Query Neighborhood Hits	80	Target Neighborhood Hits	341	Shared Neighborhood Hits	27
SwissProt Accessions	O75475, O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6	Gene names	PSIP1, DFS70, LEDGF, PSIP2
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) (Dense fine speckles 70 kDa protein) (DFS 70) (CLL-associated antigen KW-7).

DNM3L_HUMAN
NC score	0.281135 (rank : 12)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	80	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJW3, Q9BUJ4	Gene names	DNMT3L
Domain Architecture	No domain graphic available
Description	DNA (cytosine-5)-methyltransferase 3-like.

DNM3L_MOUSE
NC score	0.277762 (rank : 13)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	80	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CWR8	Gene names	Dnmt3l
Domain Architecture	No domain graphic available
Description	DNA (cytosine-5)-methyltransferase 3-like.

ZCPW1_HUMAN
NC score	0.210265 (rank : 14)	θ value	0.163984 (rank : 22)
Query Neighborhood Hits	80	Target Neighborhood Hits	116	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H0M4, Q8NA98, Q9BUD0, Q9NWF7	Gene names	ZCWPW1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1.

ZCPW1_MOUSE
NC score	0.205481 (rank : 15)	θ value	0.0193708 (rank : 15)
Query Neighborhood Hits	80	Target Neighborhood Hits	307	Shared Neighborhood Hits	27
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

MSH6_MOUSE
NC score	0.203315 (rank : 16)	θ value	0.00228821 (rank : 10)
Query Neighborhood Hits	80	Target Neighborhood Hits	55	Shared Neighborhood Hits	20
SwissProt Accessions	P54276, O54710	Gene names	Msh6, Gtmbp
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

MSH6_HUMAN
NC score	0.195746 (rank : 17)	θ value	0.0113563 (rank : 14)
Query Neighborhood Hits	80	Target Neighborhood Hits	81	Shared Neighborhood Hits	21
SwissProt Accessions	P52701, O43706, O43917, Q8TCX4, Q9BTB5	Gene names	MSH6, GTBP
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

MBD5_HUMAN
NC score	0.138878 (rank : 18)	θ value	0.279714 (rank : 23)
Query Neighborhood Hits	80	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

NSD1_HUMAN
NC score	0.127338 (rank : 19)	θ value	0.0961366 (rank : 19)
Query Neighborhood Hits	80	Target Neighborhood Hits	427	Shared Neighborhood Hits	28
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

ZMY11_MOUSE
NC score	0.125490 (rank : 20)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	80	Target Neighborhood Hits	198	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

ZMY11_HUMAN
NC score	0.124808 (rank : 21)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	80	Target Neighborhood Hits	201	Shared Neighborhood Hits	21
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

PKCB1_HUMAN
NC score	0.123967 (rank : 22)	θ value	0.279714 (rank : 24)
Query Neighborhood Hits	80	Target Neighborhood Hits	488	Shared Neighborhood Hits	30
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

NSD1_MOUSE
NC score	0.104737 (rank : 23)	θ value	0.47712 (rank : 28)
Query Neighborhood Hits	80	Target Neighborhood Hits	472	Shared Neighborhood Hits	29
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

TAF1C_MOUSE
NC score	0.080909 (rank : 24)	θ value	0.125558 (rank : 21)
Query Neighborhood Hits	80	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PDZ2, P97359, Q3U3B6, Q8BN54	Gene names	Taf1c
Domain Architecture	No domain graphic available
Description	TATA box-binding protein-associated factor, RNA polymerase I, subunit C (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (TBP-associated factor RNA polymerase I 95 kDa) (TAFI95).

SET1A_HUMAN
NC score	0.075227 (rank : 25)	θ value	0.62314 (rank : 29)
Query Neighborhood Hits	80	Target Neighborhood Hits	690	Shared Neighborhood Hits	25
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

TARA_MOUSE
NC score	0.073832 (rank : 26)	θ value	0.00509761 (rank : 11)
Query Neighborhood Hits	80	Target Neighborhood Hits	1133	Shared Neighborhood Hits	20
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TXND2_HUMAN
NC score	0.067233 (rank : 27)	θ value	0.62314 (rank : 30)
Query Neighborhood Hits	80	Target Neighborhood Hits	793	Shared Neighborhood Hits	29
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

JPH2_HUMAN
NC score	0.063463 (rank : 28)	θ value	0.0252991 (rank : 16)
Query Neighborhood Hits	80	Target Neighborhood Hits	639	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

TMAP1_HUMAN
NC score	0.062030 (rank : 29)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	80	Target Neighborhood Hits	140	Shared Neighborhood Hits	10
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

XRCC1_MOUSE
NC score	0.060504 (rank : 30)	θ value	0.813845 (rank : 35)
Query Neighborhood Hits	80	Target Neighborhood Hits	242	Shared Neighborhood Hits	10
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

SIVA_HUMAN
NC score	0.057558 (rank : 31)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	80	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	O15304, Q96P98, Q9UPD6	Gene names	SIVA
Domain Architecture
Description	Apoptosis regulatory protein Siva (CD27-binding protein) (CD27BP).

RGS3_MOUSE
NC score	0.054524 (rank : 32)	θ value	0.0736092 (rank : 17)
Query Neighborhood Hits	80	Target Neighborhood Hits	1621	Shared Neighborhood Hits	35
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

ATRX_MOUSE
NC score	0.054093 (rank : 33)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	80	Target Neighborhood Hits	682	Shared Neighborhood Hits	21
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

SC24C_HUMAN
NC score	0.051240 (rank : 34)	θ value	0.279714 (rank : 25)
Query Neighborhood Hits	80	Target Neighborhood Hits	662	Shared Neighborhood Hits	18
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SH3K1_HUMAN
NC score	0.050009 (rank : 35)	θ value	0.365318 (rank : 27)
Query Neighborhood Hits	80	Target Neighborhood Hits	341	Shared Neighborhood Hits	9
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

BLNK_MOUSE
NC score	0.049575 (rank : 36)	θ value	1.06291 (rank : 36)
Query Neighborhood Hits	80	Target Neighborhood Hits	296	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

IF4G3_MOUSE
NC score	0.049154 (rank : 37)	θ value	0.813845 (rank : 32)
Query Neighborhood Hits	80	Target Neighborhood Hits	279	Shared Neighborhood Hits	11
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

CS007_MOUSE
NC score	0.048878 (rank : 38)	θ value	1.81305 (rank : 45)
Query Neighborhood Hits	80	Target Neighborhood Hits	464	Shared Neighborhood Hits	21
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

RABX5_HUMAN
NC score	0.048177 (rank : 39)	θ value	0.813845 (rank : 34)
Query Neighborhood Hits	80	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJ41	Gene names	RABGEF1, RABEX5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5) (Rabaptin-5-associated exchange factor for Rab5).

ATN1_HUMAN
NC score	0.048001 (rank : 40)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	80	Target Neighborhood Hits	676	Shared Neighborhood Hits	23
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

NFH_MOUSE
NC score	0.047610 (rank : 41)	θ value	0.0961366 (rank : 18)
Query Neighborhood Hits	80	Target Neighborhood Hits	2247	Shared Neighborhood Hits	42
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SH3K1_MOUSE
NC score	0.045859 (rank : 42)	θ value	1.06291 (rank : 37)
Query Neighborhood Hits	80	Target Neighborhood Hits	332	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

IF4G1_HUMAN
NC score	0.041709 (rank : 43)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	80	Target Neighborhood Hits	347	Shared Neighborhood Hits	17
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

MDC1_HUMAN
NC score	0.041027 (rank : 44)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	80	Target Neighborhood Hits	1446	Shared Neighborhood Hits	33
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

IF2B2_HUMAN
NC score	0.037389 (rank : 45)	θ value	0.813845 (rank : 31)
Query Neighborhood Hits	80	Target Neighborhood Hits	142	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6M1	Gene names	IGF2BP2, IMP2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62).

REPS2_HUMAN
NC score	0.033994 (rank : 46)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	80	Target Neighborhood Hits	131	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NFH8, O43428, Q8NFI5	Gene names	REPS2, POB1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

NOP56_HUMAN
NC score	0.033480 (rank : 47)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	80	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	O00567, Q9NQ05	Gene names	NOL5A, NOP56
Domain Architecture
Description	Nucleolar protein Nop56 (Nucleolar protein 5A).

PCLO_MOUSE
NC score	0.031500 (rank : 48)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	80	Target Neighborhood Hits	2275	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

ZN318_HUMAN
NC score	0.030856 (rank : 49)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	80	Target Neighborhood Hits	497	Shared Neighborhood Hits	11
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

SASH1_MOUSE
NC score	0.030352 (rank : 50)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	80	Target Neighborhood Hits	263	Shared Neighborhood Hits	14
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

ANR11_HUMAN
NC score	0.030298 (rank : 51)	θ value	1.38821 (rank : 40)
Query Neighborhood Hits	80	Target Neighborhood Hits	1289	Shared Neighborhood Hits	20
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CBP_HUMAN
NC score	0.029976 (rank : 52)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	80	Target Neighborhood Hits	941	Shared Neighborhood Hits	28
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

RT35_MOUSE
NC score	0.029781 (rank : 53)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	80	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BJZ4, Q8VCG7	Gene names	Mrps35
Domain Architecture	No domain graphic available
Description	28S ribosomal protein S35, mitochondrial precursor (S35mt) (MRP-S35).

DDX51_HUMAN
NC score	0.029501 (rank : 54)	θ value	0.365318 (rank : 26)
Query Neighborhood Hits	80	Target Neighborhood Hits	332	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

T22D4_HUMAN
NC score	0.028948 (rank : 55)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	80	Target Neighborhood Hits	403	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

PGCA_MOUSE
NC score	0.027066 (rank : 56)	θ value	0.813845 (rank : 33)
Query Neighborhood Hits	80	Target Neighborhood Hits	643	Shared Neighborhood Hits	13
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

ROBO4_MOUSE
NC score	0.026605 (rank : 57)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	80	Target Neighborhood Hits	358	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

JHD2B_HUMAN
NC score	0.026361 (rank : 58)	θ value	1.81305 (rank : 46)
Query Neighborhood Hits	80	Target Neighborhood Hits	171	Shared Neighborhood Hits	6
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

TF65_HUMAN
NC score	0.026133 (rank : 59)	θ value	2.36792 (rank : 52)
Query Neighborhood Hits	80	Target Neighborhood Hits	115	Shared Neighborhood Hits	7
SwissProt Accessions	Q04206, Q6SLK1	Gene names	RELA, NFKB3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

SOX13_MOUSE
NC score	0.026123 (rank : 60)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	80	Target Neighborhood Hits	495	Shared Neighborhood Hits	11
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

RFX3_HUMAN
NC score	0.023822 (rank : 61)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	80	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	P48380, Q5JTL7, Q5JTL8, Q6NW13, Q8WTU4, Q95HL5, Q95HL6	Gene names	RFX3
Domain Architecture
Description	Transcription factor RFX3.

CS029_MOUSE
NC score	0.020348 (rank : 62)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	80	Target Neighborhood Hits	201	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CS00	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 homolog.

UBP51_HUMAN
NC score	0.019895 (rank : 63)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	80	Target Neighborhood Hits	162	Shared Neighborhood Hits	6
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

PTN23_HUMAN
NC score	0.018520 (rank : 64)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	80	Target Neighborhood Hits	646	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

DCX_HUMAN
NC score	0.018429 (rank : 65)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	80	Target Neighborhood Hits	141	Shared Neighborhood Hits	9
SwissProt Accessions	O43602, O43911	Gene names	DCX, DBCN, LISX
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

ETV3_HUMAN
NC score	0.018313 (rank : 66)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	80	Target Neighborhood Hits	312	Shared Neighborhood Hits	14
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

RIMB1_MOUSE
NC score	0.017838 (rank : 67)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	80	Target Neighborhood Hits	1376	Shared Neighborhood Hits	22
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

JIP3_HUMAN
NC score	0.017753 (rank : 68)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	80	Target Neighborhood Hits	1039	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

PUNC_MOUSE
NC score	0.017622 (rank : 69)	θ value	1.81305 (rank : 47)
Query Neighborhood Hits	80	Target Neighborhood Hits	501	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

TITIN_HUMAN
NC score	0.017444 (rank : 70)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	80	Target Neighborhood Hits	2923	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ELL_HUMAN
NC score	0.016789 (rank : 71)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	80	Target Neighborhood Hits	183	Shared Neighborhood Hits	4
SwissProt Accessions	P55199	Gene names	ELL, C19orf17
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

ZN533_MOUSE
NC score	0.016478 (rank : 72)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	80	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BXJ8, Q8BWQ7	Gene names	Znf533, Zfp533
Domain Architecture	No domain graphic available
Description	Zinc finger protein 533.

PDLI4_HUMAN
NC score	0.015143 (rank : 73)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	80	Target Neighborhood Hits	245	Shared Neighborhood Hits	3
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

ADA19_HUMAN
NC score	0.014104 (rank : 74)	θ value	1.38821 (rank : 39)
Query Neighborhood Hits	80	Target Neighborhood Hits	381	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

CEL_HUMAN
NC score	0.014091 (rank : 75)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	80	Target Neighborhood Hits	896	Shared Neighborhood Hits	20
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

GLI2_HUMAN
NC score	0.012922 (rank : 76)	θ value	0.125558 (rank : 20)
Query Neighborhood Hits	80	Target Neighborhood Hits	971	Shared Neighborhood Hits	9
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

GP176_MOUSE
NC score	0.011793 (rank : 77)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	80	Target Neighborhood Hits	539	Shared Neighborhood Hits	3
SwissProt Accessions	Q80WT4, Q80UC4	Gene names	Gpr176, Agr9, Gm1012
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 176 (G-protein coupled receptor AGR9).

ADCY9_HUMAN
NC score	0.010851 (rank : 78)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	80	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	O60503, O60273, Q4ZHT9, Q4ZIR5, Q9BWT4, Q9UGP2	Gene names	ADCY9, KIAA0520
Domain Architecture
Description	Adenylate cyclase type 9 (EC 4.6.1.1) (Adenylate cyclase type IX) (ATP pyrophosphate-lyase 9) (Adenylyl cyclase 9).

BRE1B_HUMAN
NC score	0.010531 (rank : 79)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	80	Target Neighborhood Hits	1040	Shared Neighborhood Hits	7
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

TENA_MOUSE
NC score	0.010214 (rank : 80)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	80	Target Neighborhood Hits	596	Shared Neighborhood Hits	6
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENX_HUMAN
NC score	0.009399 (rank : 81)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	80	Target Neighborhood Hits	789	Shared Neighborhood Hits	8
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

FZD6_MOUSE
NC score	0.007955 (rank : 82)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	80	Target Neighborhood Hits	135	Shared Neighborhood Hits	2
SwissProt Accessions	Q61089	Gene names	Fzd6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (mFz6).

ULK1_MOUSE
NC score	0.003429 (rank : 83)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	80	Target Neighborhood Hits	1214	Shared Neighborhood Hits	17
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

VGFR3_MOUSE
NC score	0.002890 (rank : 84)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	80	Target Neighborhood Hits	1056	Shared Neighborhood Hits	7
SwissProt Accessions	P35917	Gene names	Flt4, Flt-4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).