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Network neighborhood for query Sequence : RFX3_HUMAN

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RFX3_HUMAN
SwissProt Accessions	P48380, Q5JTL7, Q5JTL8, Q6NW13, Q8WTU4, Q95HL5, Q95HL6	Gene names	RFX3
Domain Architecture
Description	Transcription factor RFX3.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RFX1_HUMAN
θ value	0 (rank : 1)	NC score	0.935949 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	256	Shared Neighborhood Hits	11
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

RFX1_MOUSE
θ value	0 (rank : 2)	NC score	0.958518 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	181	Shared Neighborhood Hits	11
SwissProt Accessions	P48377	Gene names	Rfx1
Domain Architecture
Description	DNA-binding protein RFX1.

RFX2_HUMAN
θ value	0 (rank : 3)	NC score	0.992328 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	P48378	Gene names	RFX2
Domain Architecture
Description	DNA-binding protein RFX2.

RFX2_MOUSE
θ value	0 (rank : 4)	NC score	0.991995 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	P48379	Gene names	Rfx2
Domain Architecture
Description	DNA-binding protein RFX2.

RFX3_HUMAN
θ value	0 (rank : 5)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	P48380, Q5JTL7, Q5JTL8, Q6NW13, Q8WTU4, Q95HL5, Q95HL6	Gene names	RFX3
Domain Architecture
Description	Transcription factor RFX3.

RFX3_MOUSE
θ value	0 (rank : 6)	NC score	0.999865 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	P48381, Q8BLW2, Q8C0R3, Q8VBY6	Gene names	Rfx3
Domain Architecture
Description	Transcription factor RFX3.

RFX5_HUMAN
θ value	9.59137e-10 (rank : 7)	NC score	0.539997 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	59	Shared Neighborhood Hits	8
SwissProt Accessions	P48382	Gene names	RFX5
Domain Architecture
Description	DNA-binding protein RFX5 (Regulatory factor X subunit 5).

ARID2_HUMAN
θ value	0.813845 (rank : 8)	NC score	0.092618 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	302	Shared Neighborhood Hits	10
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

PWWP2_HUMAN
θ value	2.36792 (rank : 9)	NC score	0.023822 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	80	Shared Neighborhood Hits	2
SwissProt Accessions	Q6NUJ5, Q5SZI0, Q6ZQX5, Q96F43	Gene names	PWWP2
Domain Architecture	No domain graphic available
Description	PWWP domain-containing protein 2.

FREM1_MOUSE
θ value	4.03905 (rank : 10)	NC score	0.010704 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	163	Shared Neighborhood Hits	3
SwissProt Accessions	Q684R7, Q5H8C2, Q5M7B3, Q8C732	Gene names	Frem1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

ZBT37_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.007451 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	815	Shared Neighborhood Hits	6
SwissProt Accessions	Q5TC79, Q5TC80, Q96M87, Q9BQ88	Gene names	ZBTB37
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 37.

ACTN4_MOUSE
θ value	5.27518 (rank : 12)	NC score	0.006669 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	276	Shared Neighborhood Hits	5
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

SYNE1_HUMAN
θ value	5.27518 (rank : 13)	NC score	0.009940 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	1484	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

SPN90_MOUSE
θ value	6.88961 (rank : 14)	NC score	0.019991 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

ZFYV9_HUMAN
θ value	6.88961 (rank : 15)	NC score	0.011210 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	134	Shared Neighborhood Hits	4
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

EVPL_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.003702 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	895	Shared Neighborhood Hits	5
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

VP13A_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.015135 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	Q96RL7, Q5JSX9, Q5JSY0, Q5VYR5, Q702P4, Q709D0, Q86YF8, Q96S61, Q9H995, Q9Y2J1	Gene names	VPS13A, CHAC, KIAA0986
Domain Architecture
Description	Vacuolar protein sorting-associated protein 13A (Chorein) (Chorea- acanthocytosis protein).

WNK1_MOUSE
θ value	8.99809 (rank : 18)	NC score	0.005944 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	1179	Shared Neighborhood Hits	6
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

Hits sorted by NC score

RFX3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	P48380, Q5JTL7, Q5JTL8, Q6NW13, Q8WTU4, Q95HL5, Q95HL6	Gene names	RFX3
Domain Architecture
Description	Transcription factor RFX3.

RFX3_MOUSE
NC score	0.999865 (rank : 2)	θ value	0 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	P48381, Q8BLW2, Q8C0R3, Q8VBY6	Gene names	Rfx3
Domain Architecture
Description	Transcription factor RFX3.

RFX2_HUMAN
NC score	0.992328 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	P48378	Gene names	RFX2
Domain Architecture
Description	DNA-binding protein RFX2.

RFX2_MOUSE
NC score	0.991995 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	P48379	Gene names	Rfx2
Domain Architecture
Description	DNA-binding protein RFX2.

RFX1_MOUSE
NC score	0.958518 (rank : 5)	θ value	0 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	181	Shared Neighborhood Hits	11
SwissProt Accessions	P48377	Gene names	Rfx1
Domain Architecture
Description	DNA-binding protein RFX1.

RFX1_HUMAN
NC score	0.935949 (rank : 6)	θ value	0 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	256	Shared Neighborhood Hits	11
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

RFX5_HUMAN
NC score	0.539997 (rank : 7)	θ value	9.59137e-10 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	59	Shared Neighborhood Hits	8
SwissProt Accessions	P48382	Gene names	RFX5
Domain Architecture
Description	DNA-binding protein RFX5 (Regulatory factor X subunit 5).

ARID2_HUMAN
NC score	0.092618 (rank : 8)	θ value	0.813845 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	302	Shared Neighborhood Hits	10
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

PWWP2_HUMAN
NC score	0.023822 (rank : 9)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	80	Shared Neighborhood Hits	2
SwissProt Accessions	Q6NUJ5, Q5SZI0, Q6ZQX5, Q96F43	Gene names	PWWP2
Domain Architecture	No domain graphic available
Description	PWWP domain-containing protein 2.

SPN90_MOUSE
NC score	0.019991 (rank : 10)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

VP13A_HUMAN
NC score	0.015135 (rank : 11)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	Q96RL7, Q5JSX9, Q5JSY0, Q5VYR5, Q702P4, Q709D0, Q86YF8, Q96S61, Q9H995, Q9Y2J1	Gene names	VPS13A, CHAC, KIAA0986
Domain Architecture
Description	Vacuolar protein sorting-associated protein 13A (Chorein) (Chorea- acanthocytosis protein).

ZFYV9_HUMAN
NC score	0.011210 (rank : 12)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	134	Shared Neighborhood Hits	4
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

FREM1_MOUSE
NC score	0.010704 (rank : 13)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	163	Shared Neighborhood Hits	3
SwissProt Accessions	Q684R7, Q5H8C2, Q5M7B3, Q8C732	Gene names	Frem1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

SYNE1_HUMAN
NC score	0.009940 (rank : 14)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	1484	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

ZBT37_HUMAN
NC score	0.007451 (rank : 15)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	815	Shared Neighborhood Hits	6
SwissProt Accessions	Q5TC79, Q5TC80, Q96M87, Q9BQ88	Gene names	ZBTB37
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 37.

ACTN4_MOUSE
NC score	0.006669 (rank : 16)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	276	Shared Neighborhood Hits	5
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

WNK1_MOUSE
NC score	0.005944 (rank : 17)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	1179	Shared Neighborhood Hits	6
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

EVPL_HUMAN
NC score	0.003702 (rank : 18)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	895	Shared Neighborhood Hits	5
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).