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Network neighborhood for query Sequence : HDGR3_HUMAN

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HDGR3_HUMAN
SwissProt Accessions	Q9Y3E1	Gene names	HDGFRP3, HDGF2
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3) (Hepatoma- derived growth factor 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HDGR3_HUMAN
θ value	9.37149e-90 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	60	Target Neighborhood Hits	60	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y3E1	Gene names	HDGFRP3, HDGF2
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3) (Hepatoma- derived growth factor 2).

HDGR3_MOUSE
θ value	1.82896e-85 (rank : 2)	NC score	0.993137 (rank : 2)
Query Neighborhood Hits	60	Target Neighborhood Hits	42	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JMG7, Q3TRX2, Q8BQ69, Q8BR62, Q9D2M7	Gene names	Hdgfrp3
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3).

HDGF_MOUSE
θ value	1.32293e-51 (rank : 3)	NC score	0.937218 (rank : 4)
Query Neighborhood Hits	60	Target Neighborhood Hits	102	Shared Neighborhood Hits	24
SwissProt Accessions	P51859, Q8BPG7, Q9CYA4, Q9JK87	Gene names	Hdgf, Tdrm1
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF).

HDGF_HUMAN
θ value	1.61718e-49 (rank : 4)	NC score	0.948927 (rank : 3)
Query Neighborhood Hits	60	Target Neighborhood Hits	61	Shared Neighborhood Hits	22
SwissProt Accessions	P51858, Q5SZ09	Gene names	HDGF, HMG1L2
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF) (High-mobility group protein 1- like 2) (HMG-1L2).

PSIP1_HUMAN
θ value	1.28137e-46 (rank : 5)	NC score	0.821564 (rank : 6)
Query Neighborhood Hits	60	Target Neighborhood Hits	341	Shared Neighborhood Hits	32
SwissProt Accessions	O75475, O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6	Gene names	PSIP1, DFS70, LEDGF, PSIP2
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) (Dense fine speckles 70 kDa protein) (DFS 70) (CLL-associated antigen KW-7).

PSIP1_MOUSE
θ value	2.85459e-46 (rank : 6)	NC score	0.828565 (rank : 5)
Query Neighborhood Hits	60	Target Neighborhood Hits	313	Shared Neighborhood Hits	33
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

PWWP2_HUMAN
θ value	0.000158464 (rank : 7)	NC score	0.374703 (rank : 7)
Query Neighborhood Hits	60	Target Neighborhood Hits	80	Shared Neighborhood Hits	21
SwissProt Accessions	Q6NUJ5, Q5SZI0, Q6ZQX5, Q96F43	Gene names	PWWP2
Domain Architecture	No domain graphic available
Description	PWWP domain-containing protein 2.

MSH6_HUMAN
θ value	0.0563607 (rank : 8)	NC score	0.169029 (rank : 10)
Query Neighborhood Hits	60	Target Neighborhood Hits	81	Shared Neighborhood Hits	23
SwissProt Accessions	P52701, O43706, O43917, Q8TCX4, Q9BTB5	Gene names	MSH6, GTBP
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

ZCPW1_MOUSE
θ value	0.0736092 (rank : 9)	NC score	0.188052 (rank : 8)
Query Neighborhood Hits	60	Target Neighborhood Hits	307	Shared Neighborhood Hits	26
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

PDE1C_MOUSE
θ value	0.0961366 (rank : 10)	NC score	0.025785 (rank : 58)
Query Neighborhood Hits	60	Target Neighborhood Hits	161	Shared Neighborhood Hits	7
SwissProt Accessions	Q64338, Q62045, Q8BSV6	Gene names	Pde1c
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C).

MSH6_MOUSE
θ value	0.125558 (rank : 11)	NC score	0.164848 (rank : 11)
Query Neighborhood Hits	60	Target Neighborhood Hits	55	Shared Neighborhood Hits	22
SwissProt Accessions	P54276, O54710	Gene names	Msh6, Gtmbp
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

PKCB1_HUMAN
θ value	0.163984 (rank : 12)	NC score	0.143708 (rank : 12)
Query Neighborhood Hits	60	Target Neighborhood Hits	488	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

NSD1_HUMAN
θ value	0.21417 (rank : 13)	NC score	0.107145 (rank : 15)
Query Neighborhood Hits	60	Target Neighborhood Hits	427	Shared Neighborhood Hits	20
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	0.21417 (rank : 14)	NC score	0.096717 (rank : 18)
Query Neighborhood Hits	60	Target Neighborhood Hits	472	Shared Neighborhood Hits	22
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

LEO1_MOUSE
θ value	0.365318 (rank : 15)	NC score	0.074529 (rank : 23)
Query Neighborhood Hits	60	Target Neighborhood Hits	946	Shared Neighborhood Hits	31
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

VPS72_MOUSE
θ value	0.365318 (rank : 16)	NC score	0.078515 (rank : 21)
Query Neighborhood Hits	60	Target Neighborhood Hits	286	Shared Neighborhood Hits	19
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

HIRP3_HUMAN
θ value	0.47712 (rank : 17)	NC score	0.067435 (rank : 26)
Query Neighborhood Hits	60	Target Neighborhood Hits	323	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

ELOA1_MOUSE
θ value	0.62314 (rank : 18)	NC score	0.045340 (rank : 41)
Query Neighborhood Hits	60	Target Neighborhood Hits	152	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CB77, Q80VB2, Q9R0Q5	Gene names	Tceb3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

ZCPW1_HUMAN
θ value	0.813845 (rank : 19)	NC score	0.178178 (rank : 9)
Query Neighborhood Hits	60	Target Neighborhood Hits	116	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H0M4, Q8NA98, Q9BUD0, Q9NWF7	Gene names	ZCWPW1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1.

RBP26_HUMAN
θ value	1.06291 (rank : 20)	NC score	0.038284 (rank : 43)
Query Neighborhood Hits	60	Target Neighborhood Hits	146	Shared Neighborhood Hits	4
SwissProt Accessions	Q68DN6, Q6V1X0	Gene names	RANBP2L6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 6 (RanBP2L6).

MBD5_HUMAN
θ value	1.38821 (rank : 21)	NC score	0.070727 (rank : 25)
Query Neighborhood Hits	60	Target Neighborhood Hits	176	Shared Neighborhood Hits	15
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

ZMY11_HUMAN
θ value	1.38821 (rank : 22)	NC score	0.133232 (rank : 14)
Query Neighborhood Hits	60	Target Neighborhood Hits	201	Shared Neighborhood Hits	21
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

ZMY11_MOUSE
θ value	1.38821 (rank : 23)	NC score	0.133750 (rank : 13)
Query Neighborhood Hits	60	Target Neighborhood Hits	198	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

DNM3A_HUMAN
θ value	1.81305 (rank : 24)	NC score	0.074195 (rank : 24)
Query Neighborhood Hits	60	Target Neighborhood Hits	104	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y6K1, Q8WXU9	Gene names	DNMT3A
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA).

DNM3A_MOUSE
θ value	1.81305 (rank : 25)	NC score	0.079467 (rank : 20)
Query Neighborhood Hits	60	Target Neighborhood Hits	91	Shared Neighborhood Hits	18
SwissProt Accessions	O88508, Q3UH24, Q8CJ60, Q922J0, Q9CSE1	Gene names	Dnmt3a
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA).

KMHN1_MOUSE
θ value	1.81305 (rank : 26)	NC score	0.011620 (rank : 66)
Query Neighborhood Hits	60	Target Neighborhood Hits	949	Shared Neighborhood Hits	9
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

RBP2_HUMAN
θ value	1.81305 (rank : 27)	NC score	0.025260 (rank : 59)
Query Neighborhood Hits	60	Target Neighborhood Hits	249	Shared Neighborhood Hits	6
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

RNUXA_MOUSE
θ value	1.81305 (rank : 28)	NC score	0.044615 (rank : 42)
Query Neighborhood Hits	60	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJT9, Q8BSR8	Gene names	Rnuxa, Phax
Domain Architecture	No domain graphic available
Description	RNA U small nuclear RNA export adapter protein (Phosphorylated adapter RNA export protein).

ATX2_HUMAN
θ value	2.36792 (rank : 29)	NC score	0.031916 (rank : 45)
Query Neighborhood Hits	60	Target Neighborhood Hits	375	Shared Neighborhood Hits	7
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

ATX2_MOUSE
θ value	2.36792 (rank : 30)	NC score	0.030726 (rank : 49)
Query Neighborhood Hits	60	Target Neighborhood Hits	445	Shared Neighborhood Hits	6
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

VPS72_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.067410 (rank : 27)
Query Neighborhood Hits	60	Target Neighborhood Hits	274	Shared Neighborhood Hits	20
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

AFF4_HUMAN
θ value	3.0926 (rank : 32)	NC score	0.028014 (rank : 54)
Query Neighborhood Hits	60	Target Neighborhood Hits	611	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

DNM3B_HUMAN
θ value	3.0926 (rank : 33)	NC score	0.096856 (rank : 16)
Query Neighborhood Hits	60	Target Neighborhood Hits	59	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UBC3, Q9UBD4, Q9UJQ5, Q9UKA6, Q9UNE5, Q9Y5R9, Q9Y5S0	Gene names	DNMT3B
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase HsaIIIB) (DNA MTase HsaIIIB) (M.HsaIIIB).

DNM3B_MOUSE
θ value	3.0926 (rank : 34)	NC score	0.096735 (rank : 17)
Query Neighborhood Hits	60	Target Neighborhood Hits	61	Shared Neighborhood Hits	22
SwissProt Accessions	O88509, O88510, O88511	Gene names	Dnmt3b
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase MmuIIIB) (DNA MTase MmuIIIB) (M.MmuIIIB).

GP73_MOUSE
θ value	3.0926 (rank : 35)	NC score	0.028263 (rank : 53)
Query Neighborhood Hits	60	Target Neighborhood Hits	506	Shared Neighborhood Hits	9
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

NRDC_MOUSE
θ value	3.0926 (rank : 36)	NC score	0.034084 (rank : 44)
Query Neighborhood Hits	60	Target Neighborhood Hits	96	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BHG1	Gene names	Nrd1
Domain Architecture
Description	Nardilysin precursor (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C).

TRI44_HUMAN
θ value	3.0926 (rank : 37)	NC score	0.030010 (rank : 52)
Query Neighborhood Hits	60	Target Neighborhood Hits	393	Shared Neighborhood Hits	15
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

CASZ1_HUMAN
θ value	4.03905 (rank : 38)	NC score	0.016279 (rank : 61)
Query Neighborhood Hits	60	Target Neighborhood Hits	473	Shared Neighborhood Hits	3
SwissProt Accessions	Q86V15, Q5T9S1, Q8WX49, Q8WX50, Q9BT16, Q9NXC6	Gene names	CASZ1, CST, ZNF693
Domain Architecture	No domain graphic available
Description	Castor homolog 1 zinc finger protein (Castor-related protein) (Zinc finger protein 693).

NPBL_MOUSE
θ value	4.03905 (rank : 39)	NC score	0.057872 (rank : 31)
Query Neighborhood Hits	60	Target Neighborhood Hits	1041	Shared Neighborhood Hits	25
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NRDC_HUMAN
θ value	4.03905 (rank : 40)	NC score	0.030888 (rank : 48)
Query Neighborhood Hits	60	Target Neighborhood Hits	60	Shared Neighborhood Hits	10
SwissProt Accessions	O43847, O15241, O15242, Q5VUL0, Q96HB2, Q9NU57	Gene names	NRD1
Domain Architecture
Description	Nardilysin precursor (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C).

AN32A_MOUSE
θ value	5.27518 (rank : 41)	NC score	0.031634 (rank : 46)
Query Neighborhood Hits	60	Target Neighborhood Hits	254	Shared Neighborhood Hits	12
SwissProt Accessions	O35381, P97437	Gene names	Anp32a, Anp32, Lanp
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein).

AN32C_MOUSE
θ value	5.27518 (rank : 42)	NC score	0.031634 (rank : 47)
Query Neighborhood Hits	60	Target Neighborhood Hits	254	Shared Neighborhood Hits	12
SwissProt Accessions	Q64G17	Gene names	Anp32c
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member C.

ERIC1_HUMAN
θ value	5.27518 (rank : 43)	NC score	0.047615 (rank : 40)
Query Neighborhood Hits	60	Target Neighborhood Hits	364	Shared Neighborhood Hits	19
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

GBF1_HUMAN
θ value	5.27518 (rank : 44)	NC score	0.012296 (rank : 65)
Query Neighborhood Hits	60	Target Neighborhood Hits	142	Shared Neighborhood Hits	3
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

NCKX1_HUMAN
θ value	5.27518 (rank : 45)	NC score	0.026747 (rank : 57)
Query Neighborhood Hits	60	Target Neighborhood Hits	223	Shared Neighborhood Hits	14
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

NKTR_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.027278 (rank : 56)
Query Neighborhood Hits	60	Target Neighborhood Hits	658	Shared Neighborhood Hits	24
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

OTOF_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.014736 (rank : 62)
Query Neighborhood Hits	60	Target Neighborhood Hits	168	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

HUWE1_HUMAN
θ value	6.88961 (rank : 48)	NC score	0.011594 (rank : 67)
Query Neighborhood Hits	60	Target Neighborhood Hits	443	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

MATR3_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.030141 (rank : 51)
Query Neighborhood Hits	60	Target Neighborhood Hits	325	Shared Neighborhood Hits	19
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

TCAL5_HUMAN
θ value	6.88961 (rank : 50)	NC score	0.076380 (rank : 22)
Query Neighborhood Hits	60	Target Neighborhood Hits	806	Shared Neighborhood Hits	31
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

ABTAP_HUMAN
θ value	8.99809 (rank : 51)	NC score	0.017220 (rank : 60)
Query Neighborhood Hits	60	Target Neighborhood Hits	290	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H501, Q86X92, Q9H9Q5, Q9HA35, Q9NX93, Q9P1S6	Gene names	ABTAP, C20orf6
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

CD2L1_HUMAN
θ value	8.99809 (rank : 52)	NC score	0.003453 (rank : 70)
Query Neighborhood Hits	60	Target Neighborhood Hits	1467	Shared Neighborhood Hits	20
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CT2NL_HUMAN
θ value	8.99809 (rank : 53)	NC score	0.014372 (rank : 63)
Query Neighborhood Hits	60	Target Neighborhood Hits	1059	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

DCDC2_MOUSE
θ value	8.99809 (rank : 54)	NC score	0.027595 (rank : 55)
Query Neighborhood Hits	60	Target Neighborhood Hits	247	Shared Neighborhood Hits	19
SwissProt Accessions	Q5DU00, Q5SZU0, Q80Y99	Gene names	Dcdc2, Kiaa1154
Domain Architecture	No domain graphic available
Description	Doublecortin domain-containing protein 2.

LEO1_HUMAN
θ value	8.99809 (rank : 55)	NC score	0.061575 (rank : 30)
Query Neighborhood Hits	60	Target Neighborhood Hits	958	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

NFM_MOUSE
θ value	8.99809 (rank : 56)	NC score	0.014227 (rank : 64)
Query Neighborhood Hits	60	Target Neighborhood Hits	1159	Shared Neighborhood Hits	24
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

POK3_HUMAN
θ value	8.99809 (rank : 57)	NC score	0.004746 (rank : 69)
Query Neighborhood Hits	60	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WJR5, O15312	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Pol protein (HERV-K(C19) Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

RNF8_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.005211 (rank : 68)
Query Neighborhood Hits	60	Target Neighborhood Hits	622	Shared Neighborhood Hits	5
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RNUXA_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.030153 (rank : 50)
Query Neighborhood Hits	60	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H814, Q9H8W1	Gene names	RNUXA, PHAX
Domain Architecture	No domain graphic available
Description	RNA U small nuclear RNA export adapter protein (Phosphorylated adapter RNA export protein).

UBF1_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.051554 (rank : 38)
Query Neighborhood Hits	60	Target Neighborhood Hits	415	Shared Neighborhood Hits	16
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

ARS2_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.057819 (rank : 32)
Query Neighborhood Hits	60	Target Neighborhood Hits	212	Shared Neighborhood Hits	12
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

ELOA1_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.051721 (rank : 37)
Query Neighborhood Hits	60	Target Neighborhood Hits	388	Shared Neighborhood Hits	15
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

HMGN2_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.085334 (rank : 19)
Query Neighborhood Hits	60	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P05204, Q6FGI5, Q96C64	Gene names	HMGN2, HMG17
Domain Architecture	No domain graphic available
Description	Nonhistone chromosomal protein HMG-17 (High-mobility group nucleosome- binding domain-containing protein 2).

HMGN2_MOUSE
θ value	θ > 10 (rank : 64)	NC score	0.066521 (rank : 28)
Query Neighborhood Hits	60	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P09602	Gene names	Hmgn2, Hmg-17, Hmg17
Domain Architecture	No domain graphic available
Description	Nonhistone chromosomal protein HMG-17 (High-mobility group nucleosome- binding domain-containing protein 2).

IWS1_MOUSE
θ value	θ > 10 (rank : 65)	NC score	0.056220 (rank : 33)
Query Neighborhood Hits	60	Target Neighborhood Hits	1258	Shared Neighborhood Hits	31
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NIPBL_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.052328 (rank : 36)
Query Neighborhood Hits	60	Target Neighborhood Hits	1311	Shared Neighborhood Hits	27
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NSBP1_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.062700 (rank : 29)
Query Neighborhood Hits	60	Target Neighborhood Hits	251	Shared Neighborhood Hits	15
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

PTMS_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.056183 (rank : 34)
Query Neighborhood Hits	60	Target Neighborhood Hits	68	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

TGON2_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.050721 (rank : 39)
Query Neighborhood Hits	60	Target Neighborhood Hits	1037	Shared Neighborhood Hits	25
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TXND2_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.052446 (rank : 35)
Query Neighborhood Hits	60	Target Neighborhood Hits	828	Shared Neighborhood Hits	24
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

Hits sorted by NC score

HDGR3_HUMAN
NC score	0.999962 (rank : 1)	θ value	9.37149e-90 (rank : 1)
Query Neighborhood Hits	60	Target Neighborhood Hits	60	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y3E1	Gene names	HDGFRP3, HDGF2
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3) (Hepatoma- derived growth factor 2).

HDGR3_MOUSE
NC score	0.993137 (rank : 2)	θ value	1.82896e-85 (rank : 2)
Query Neighborhood Hits	60	Target Neighborhood Hits	42	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JMG7, Q3TRX2, Q8BQ69, Q8BR62, Q9D2M7	Gene names	Hdgfrp3
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3).

HDGF_HUMAN
NC score	0.948927 (rank : 3)	θ value	1.61718e-49 (rank : 4)
Query Neighborhood Hits	60	Target Neighborhood Hits	61	Shared Neighborhood Hits	22
SwissProt Accessions	P51858, Q5SZ09	Gene names	HDGF, HMG1L2
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF) (High-mobility group protein 1- like 2) (HMG-1L2).

HDGF_MOUSE
NC score	0.937218 (rank : 4)	θ value	1.32293e-51 (rank : 3)
Query Neighborhood Hits	60	Target Neighborhood Hits	102	Shared Neighborhood Hits	24
SwissProt Accessions	P51859, Q8BPG7, Q9CYA4, Q9JK87	Gene names	Hdgf, Tdrm1
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF).

PSIP1_MOUSE
NC score	0.828565 (rank : 5)	θ value	2.85459e-46 (rank : 6)
Query Neighborhood Hits	60	Target Neighborhood Hits	313	Shared Neighborhood Hits	33
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

PSIP1_HUMAN
NC score	0.821564 (rank : 6)	θ value	1.28137e-46 (rank : 5)
Query Neighborhood Hits	60	Target Neighborhood Hits	341	Shared Neighborhood Hits	32
SwissProt Accessions	O75475, O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6	Gene names	PSIP1, DFS70, LEDGF, PSIP2
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) (Dense fine speckles 70 kDa protein) (DFS 70) (CLL-associated antigen KW-7).

PWWP2_HUMAN
NC score	0.374703 (rank : 7)	θ value	0.000158464 (rank : 7)
Query Neighborhood Hits	60	Target Neighborhood Hits	80	Shared Neighborhood Hits	21
SwissProt Accessions	Q6NUJ5, Q5SZI0, Q6ZQX5, Q96F43	Gene names	PWWP2
Domain Architecture	No domain graphic available
Description	PWWP domain-containing protein 2.

ZCPW1_MOUSE
NC score	0.188052 (rank : 8)	θ value	0.0736092 (rank : 9)
Query Neighborhood Hits	60	Target Neighborhood Hits	307	Shared Neighborhood Hits	26
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

ZCPW1_HUMAN
NC score	0.178178 (rank : 9)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	60	Target Neighborhood Hits	116	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H0M4, Q8NA98, Q9BUD0, Q9NWF7	Gene names	ZCWPW1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1.

MSH6_HUMAN
NC score	0.169029 (rank : 10)	θ value	0.0563607 (rank : 8)
Query Neighborhood Hits	60	Target Neighborhood Hits	81	Shared Neighborhood Hits	23
SwissProt Accessions	P52701, O43706, O43917, Q8TCX4, Q9BTB5	Gene names	MSH6, GTBP
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

MSH6_MOUSE
NC score	0.164848 (rank : 11)	θ value	0.125558 (rank : 11)
Query Neighborhood Hits	60	Target Neighborhood Hits	55	Shared Neighborhood Hits	22
SwissProt Accessions	P54276, O54710	Gene names	Msh6, Gtmbp
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

PKCB1_HUMAN
NC score	0.143708 (rank : 12)	θ value	0.163984 (rank : 12)
Query Neighborhood Hits	60	Target Neighborhood Hits	488	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

ZMY11_MOUSE
NC score	0.133750 (rank : 13)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	60	Target Neighborhood Hits	198	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

ZMY11_HUMAN
NC score	0.133232 (rank : 14)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	60	Target Neighborhood Hits	201	Shared Neighborhood Hits	21
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

NSD1_HUMAN
NC score	0.107145 (rank : 15)	θ value	0.21417 (rank : 13)
Query Neighborhood Hits	60	Target Neighborhood Hits	427	Shared Neighborhood Hits	20
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

DNM3B_HUMAN
NC score	0.096856 (rank : 16)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	60	Target Neighborhood Hits	59	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UBC3, Q9UBD4, Q9UJQ5, Q9UKA6, Q9UNE5, Q9Y5R9, Q9Y5S0	Gene names	DNMT3B
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase HsaIIIB) (DNA MTase HsaIIIB) (M.HsaIIIB).

DNM3B_MOUSE
NC score	0.096735 (rank : 17)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	60	Target Neighborhood Hits	61	Shared Neighborhood Hits	22
SwissProt Accessions	O88509, O88510, O88511	Gene names	Dnmt3b
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase MmuIIIB) (DNA MTase MmuIIIB) (M.MmuIIIB).

NSD1_MOUSE
NC score	0.096717 (rank : 18)	θ value	0.21417 (rank : 14)
Query Neighborhood Hits	60	Target Neighborhood Hits	472	Shared Neighborhood Hits	22
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

HMGN2_HUMAN
NC score	0.085334 (rank : 19)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	60	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P05204, Q6FGI5, Q96C64	Gene names	HMGN2, HMG17
Domain Architecture	No domain graphic available
Description	Nonhistone chromosomal protein HMG-17 (High-mobility group nucleosome- binding domain-containing protein 2).

DNM3A_MOUSE
NC score	0.079467 (rank : 20)	θ value	1.81305 (rank : 25)
Query Neighborhood Hits	60	Target Neighborhood Hits	91	Shared Neighborhood Hits	18
SwissProt Accessions	O88508, Q3UH24, Q8CJ60, Q922J0, Q9CSE1	Gene names	Dnmt3a
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA).

VPS72_MOUSE
NC score	0.078515 (rank : 21)	θ value	0.365318 (rank : 16)
Query Neighborhood Hits	60	Target Neighborhood Hits	286	Shared Neighborhood Hits	19
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

TCAL5_HUMAN
NC score	0.076380 (rank : 22)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	60	Target Neighborhood Hits	806	Shared Neighborhood Hits	31
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

LEO1_MOUSE
NC score	0.074529 (rank : 23)	θ value	0.365318 (rank : 15)
Query Neighborhood Hits	60	Target Neighborhood Hits	946	Shared Neighborhood Hits	31
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

DNM3A_HUMAN
NC score	0.074195 (rank : 24)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	60	Target Neighborhood Hits	104	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y6K1, Q8WXU9	Gene names	DNMT3A
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA).

MBD5_HUMAN
NC score	0.070727 (rank : 25)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	60	Target Neighborhood Hits	176	Shared Neighborhood Hits	15
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

HIRP3_HUMAN
NC score	0.067435 (rank : 26)	θ value	0.47712 (rank : 17)
Query Neighborhood Hits	60	Target Neighborhood Hits	323	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

VPS72_HUMAN
NC score	0.067410 (rank : 27)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	60	Target Neighborhood Hits	274	Shared Neighborhood Hits	20
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

HMGN2_MOUSE
NC score	0.066521 (rank : 28)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	60	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P09602	Gene names	Hmgn2, Hmg-17, Hmg17
Domain Architecture	No domain graphic available
Description	Nonhistone chromosomal protein HMG-17 (High-mobility group nucleosome- binding domain-containing protein 2).

NSBP1_HUMAN
NC score	0.062700 (rank : 29)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	60	Target Neighborhood Hits	251	Shared Neighborhood Hits	15
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

LEO1_HUMAN
NC score	0.061575 (rank : 30)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	60	Target Neighborhood Hits	958	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

NPBL_MOUSE
NC score	0.057872 (rank : 31)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	60	Target Neighborhood Hits	1041	Shared Neighborhood Hits	25
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

ARS2_MOUSE
NC score	0.057819 (rank : 32)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	60	Target Neighborhood Hits	212	Shared Neighborhood Hits	12
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

IWS1_MOUSE
NC score	0.056220 (rank : 33)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	60	Target Neighborhood Hits	1258	Shared Neighborhood Hits	31
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PTMS_MOUSE
NC score	0.056183 (rank : 34)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	60	Target Neighborhood Hits	68	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

TXND2_MOUSE
NC score	0.052446 (rank : 35)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	60	Target Neighborhood Hits	828	Shared Neighborhood Hits	24
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

NIPBL_HUMAN
NC score	0.052328 (rank : 36)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	60	Target Neighborhood Hits	1311	Shared Neighborhood Hits	27
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

ELOA1_HUMAN
NC score	0.051721 (rank : 37)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	60	Target Neighborhood Hits	388	Shared Neighborhood Hits	15
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

UBF1_HUMAN
NC score	0.051554 (rank : 38)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	60	Target Neighborhood Hits	415	Shared Neighborhood Hits	16
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

TGON2_HUMAN
NC score	0.050721 (rank : 39)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	60	Target Neighborhood Hits	1037	Shared Neighborhood Hits	25
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

ERIC1_HUMAN
NC score	0.047615 (rank : 40)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	60	Target Neighborhood Hits	364	Shared Neighborhood Hits	19
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

ELOA1_MOUSE
NC score	0.045340 (rank : 41)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	60	Target Neighborhood Hits	152	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CB77, Q80VB2, Q9R0Q5	Gene names	Tceb3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

RNUXA_MOUSE
NC score	0.044615 (rank : 42)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	60	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJT9, Q8BSR8	Gene names	Rnuxa, Phax
Domain Architecture	No domain graphic available
Description	RNA U small nuclear RNA export adapter protein (Phosphorylated adapter RNA export protein).

RBP26_HUMAN
NC score	0.038284 (rank : 43)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	60	Target Neighborhood Hits	146	Shared Neighborhood Hits	4
SwissProt Accessions	Q68DN6, Q6V1X0	Gene names	RANBP2L6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 6 (RanBP2L6).

NRDC_MOUSE
NC score	0.034084 (rank : 44)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	60	Target Neighborhood Hits	96	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BHG1	Gene names	Nrd1
Domain Architecture
Description	Nardilysin precursor (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C).

ATX2_HUMAN
NC score	0.031916 (rank : 45)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	60	Target Neighborhood Hits	375	Shared Neighborhood Hits	7
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

AN32A_MOUSE
NC score	0.031634 (rank : 46)	θ value	5.27518 (rank : 41)
Query Neighborhood Hits	60	Target Neighborhood Hits	254	Shared Neighborhood Hits	12
SwissProt Accessions	O35381, P97437	Gene names	Anp32a, Anp32, Lanp
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein).

AN32C_MOUSE
NC score	0.031634 (rank : 47)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	60	Target Neighborhood Hits	254	Shared Neighborhood Hits	12
SwissProt Accessions	Q64G17	Gene names	Anp32c
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member C.

NRDC_HUMAN
NC score	0.030888 (rank : 48)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	60	Target Neighborhood Hits	60	Shared Neighborhood Hits	10
SwissProt Accessions	O43847, O15241, O15242, Q5VUL0, Q96HB2, Q9NU57	Gene names	NRD1
Domain Architecture
Description	Nardilysin precursor (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C).

ATX2_MOUSE
NC score	0.030726 (rank : 49)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	60	Target Neighborhood Hits	445	Shared Neighborhood Hits	6
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

RNUXA_HUMAN
NC score	0.030153 (rank : 50)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	60	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H814, Q9H8W1	Gene names	RNUXA, PHAX
Domain Architecture	No domain graphic available
Description	RNA U small nuclear RNA export adapter protein (Phosphorylated adapter RNA export protein).

MATR3_HUMAN
NC score	0.030141 (rank : 51)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	60	Target Neighborhood Hits	325	Shared Neighborhood Hits	19
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

TRI44_HUMAN
NC score	0.030010 (rank : 52)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	60	Target Neighborhood Hits	393	Shared Neighborhood Hits	15
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

GP73_MOUSE
NC score	0.028263 (rank : 53)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	60	Target Neighborhood Hits	506	Shared Neighborhood Hits	9
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

AFF4_HUMAN
NC score	0.028014 (rank : 54)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	60	Target Neighborhood Hits	611	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

DCDC2_MOUSE
NC score	0.027595 (rank : 55)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	60	Target Neighborhood Hits	247	Shared Neighborhood Hits	19
SwissProt Accessions	Q5DU00, Q5SZU0, Q80Y99	Gene names	Dcdc2, Kiaa1154
Domain Architecture	No domain graphic available
Description	Doublecortin domain-containing protein 2.

NKTR_HUMAN
NC score	0.027278 (rank : 56)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	60	Target Neighborhood Hits	658	Shared Neighborhood Hits	24
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

NCKX1_HUMAN
NC score	0.026747 (rank : 57)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	60	Target Neighborhood Hits	223	Shared Neighborhood Hits	14
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

PDE1C_MOUSE
NC score	0.025785 (rank : 58)	θ value	0.0961366 (rank : 10)
Query Neighborhood Hits	60	Target Neighborhood Hits	161	Shared Neighborhood Hits	7
SwissProt Accessions	Q64338, Q62045, Q8BSV6	Gene names	Pde1c
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C).

RBP2_HUMAN
NC score	0.025260 (rank : 59)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	60	Target Neighborhood Hits	249	Shared Neighborhood Hits	6
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

ABTAP_HUMAN
NC score	0.017220 (rank : 60)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	60	Target Neighborhood Hits	290	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H501, Q86X92, Q9H9Q5, Q9HA35, Q9NX93, Q9P1S6	Gene names	ABTAP, C20orf6
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

CASZ1_HUMAN
NC score	0.016279 (rank : 61)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	60	Target Neighborhood Hits	473	Shared Neighborhood Hits	3
SwissProt Accessions	Q86V15, Q5T9S1, Q8WX49, Q8WX50, Q9BT16, Q9NXC6	Gene names	CASZ1, CST, ZNF693
Domain Architecture	No domain graphic available
Description	Castor homolog 1 zinc finger protein (Castor-related protein) (Zinc finger protein 693).

OTOF_HUMAN
NC score	0.014736 (rank : 62)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	60	Target Neighborhood Hits	168	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

CT2NL_HUMAN
NC score	0.014372 (rank : 63)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	60	Target Neighborhood Hits	1059	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

NFM_MOUSE
NC score	0.014227 (rank : 64)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	60	Target Neighborhood Hits	1159	Shared Neighborhood Hits	24
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

GBF1_HUMAN
NC score	0.012296 (rank : 65)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	60	Target Neighborhood Hits	142	Shared Neighborhood Hits	3
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

KMHN1_MOUSE
NC score	0.011620 (rank : 66)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	60	Target Neighborhood Hits	949	Shared Neighborhood Hits	9
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

HUWE1_HUMAN
NC score	0.011594 (rank : 67)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	60	Target Neighborhood Hits	443	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

RNF8_HUMAN
NC score	0.005211 (rank : 68)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	60	Target Neighborhood Hits	622	Shared Neighborhood Hits	5
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

POK3_HUMAN
NC score	0.004746 (rank : 69)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	60	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WJR5, O15312	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Pol protein (HERV-K(C19) Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

CD2L1_HUMAN
NC score	0.003453 (rank : 70)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	60	Target Neighborhood Hits	1467	Shared Neighborhood Hits	20
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).