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Network neighborhood for query Sequence : GBF1_HUMAN

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GBF1_HUMAN
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GBF1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	142	Target Neighborhood Hits	142	Shared Neighborhood Hits	142
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

BIG2_HUMAN
θ value	4.10295e-61 (rank : 2)	NC score	0.868836 (rank : 3)
Query Neighborhood Hits	142	Target Neighborhood Hits	66	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

BIG1_HUMAN
θ value	3.59435e-57 (rank : 3)	NC score	0.869742 (rank : 2)
Query Neighborhood Hits	142	Target Neighborhood Hits	76	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

CYH3_HUMAN
θ value	9.20422e-37 (rank : 4)	NC score	0.813035 (rank : 9)
Query Neighborhood Hits	142	Target Neighborhood Hits	137	Shared Neighborhood Hits	23
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH3_MOUSE
θ value	9.20422e-37 (rank : 5)	NC score	0.807238 (rank : 15)
Query Neighborhood Hits	142	Target Neighborhood Hits	148	Shared Neighborhood Hits	23
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

CYH1_HUMAN
θ value	7.79185e-36 (rank : 6)	NC score	0.808090 (rank : 14)
Query Neighborhood Hits	142	Target Neighborhood Hits	184	Shared Neighborhood Hits	23
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH1_MOUSE
θ value	7.79185e-36 (rank : 7)	NC score	0.810310 (rank : 12)
Query Neighborhood Hits	142	Target Neighborhood Hits	176	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH2_MOUSE
θ value	6.59618e-35 (rank : 8)	NC score	0.813468 (rank : 8)
Query Neighborhood Hits	142	Target Neighborhood Hits	171	Shared Neighborhood Hits	23
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH2_HUMAN
θ value	2.50655e-34 (rank : 9)	NC score	0.812975 (rank : 10)
Query Neighborhood Hits	142	Target Neighborhood Hits	175	Shared Neighborhood Hits	23
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH4_MOUSE
θ value	1.6247e-33 (rank : 10)	NC score	0.810636 (rank : 11)
Query Neighborhood Hits	142	Target Neighborhood Hits	134	Shared Neighborhood Hits	23
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

CYH4_HUMAN
θ value	4.72714e-33 (rank : 11)	NC score	0.810015 (rank : 13)
Query Neighborhood Hits	142	Target Neighborhood Hits	135	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

IQEC1_HUMAN
θ value	5.22648e-32 (rank : 12)	NC score	0.818949 (rank : 7)
Query Neighborhood Hits	142	Target Neighborhood Hits	76	Shared Neighborhood Hits	24
SwissProt Accessions	Q6DN90, O94863, Q96D85	Gene names	IQSEC1, ARFGEP100, BRAG2, KIAA0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein).

IQEC1_MOUSE
θ value	5.22648e-32 (rank : 13)	NC score	0.821060 (rank : 5)
Query Neighborhood Hits	142	Target Neighborhood Hits	54	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R0S2, Q3TZC3, Q5DU15	Gene names	Iqsec1, Kiaa0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1.

IQEC2_MOUSE
θ value	4.42448e-31 (rank : 14)	NC score	0.782323 (rank : 16)
Query Neighborhood Hits	142	Target Neighborhood Hits	417	Shared Neighborhood Hits	50
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_HUMAN
θ value	9.8567e-31 (rank : 15)	NC score	0.781531 (rank : 17)
Query Neighborhood Hits	142	Target Neighborhood Hits	403	Shared Neighborhood Hits	48
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC3_HUMAN
θ value	1.85889e-29 (rank : 16)	NC score	0.824317 (rank : 4)
Query Neighborhood Hits	142	Target Neighborhood Hits	125	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IQEC3_MOUSE
θ value	1.85889e-29 (rank : 17)	NC score	0.819649 (rank : 6)
Query Neighborhood Hits	142	Target Neighborhood Hits	274	Shared Neighborhood Hits	45
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

PSD3_HUMAN
θ value	1.5773e-20 (rank : 18)	NC score	0.755649 (rank : 18)
Query Neighborhood Hits	142	Target Neighborhood Hits	75	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NYI0, Q9Y2F1	Gene names	PSD3, EFA6R, HCA67, KIAA0942
Domain Architecture
Description	PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).

PSD4_MOUSE
θ value	3.28887e-18 (rank : 19)	NC score	0.720633 (rank : 19)
Query Neighborhood Hits	142	Target Neighborhood Hits	78	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44	Gene names	Psd4
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).

PSD4_HUMAN
θ value	3.63628e-17 (rank : 20)	NC score	0.714305 (rank : 21)
Query Neighborhood Hits	142	Target Neighborhood Hits	178	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

FBX8_MOUSE
θ value	5.26297e-08 (rank : 21)	NC score	0.715186 (rank : 20)
Query Neighborhood Hits	142	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QZN3	Gene names	Fbxo8, Fbx8
Domain Architecture
Description	F-box only protein 8.

FBX8_HUMAN
θ value	8.97725e-08 (rank : 22)	NC score	0.712496 (rank : 22)
Query Neighborhood Hits	142	Target Neighborhood Hits	44	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NRD0, Q6UWN4, Q9NRP5, Q9UKC4	Gene names	FBXO8, FBS, FBX8
Domain Architecture
Description	F-box only protein 8 (F-box/SEC7 protein FBS).

FOG1_MOUSE
θ value	0.00298849 (rank : 23)	NC score	0.026538 (rank : 100)
Query Neighborhood Hits	142	Target Neighborhood Hits	1237	Shared Neighborhood Hits	45
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

OGFR_HUMAN
θ value	0.0113563 (rank : 24)	NC score	0.054628 (rank : 60)
Query Neighborhood Hits	142	Target Neighborhood Hits	1582	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

CUTL1_MOUSE
θ value	0.0252991 (rank : 25)	NC score	0.023492 (rank : 108)
Query Neighborhood Hits	142	Target Neighborhood Hits	1620	Shared Neighborhood Hits	41
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

B4GT1_HUMAN
θ value	0.0736092 (rank : 26)	NC score	0.026154 (rank : 101)
Query Neighborhood Hits	142	Target Neighborhood Hits	168	Shared Neighborhood Hits	3
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

SON_HUMAN
θ value	0.0736092 (rank : 27)	NC score	0.040095 (rank : 75)
Query Neighborhood Hits	142	Target Neighborhood Hits	1568	Shared Neighborhood Hits	60
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

RGS3_HUMAN
θ value	0.0961366 (rank : 28)	NC score	0.040852 (rank : 73)
Query Neighborhood Hits	142	Target Neighborhood Hits	1375	Shared Neighborhood Hits	51
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

ZBT17_MOUSE
θ value	0.0961366 (rank : 29)	NC score	0.005203 (rank : 172)
Query Neighborhood Hits	142	Target Neighborhood Hits	940	Shared Neighborhood Hits	18
SwissProt Accessions	Q60821, Q60699	Gene names	Zbtb17, Zfp100, Znf151
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 17 (Zinc finger protein 151) (Zinc finger protein 100) (Zfp-100) (Polyomavirus late initiator promoter-binding protein) (LP-1) (Zinc finger protein Z13).

OSBL2_HUMAN
θ value	0.125558 (rank : 30)	NC score	0.022951 (rank : 113)
Query Neighborhood Hits	142	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H1P3, Q9BZB1, Q9Y4B8	Gene names	OSBPL2, KIAA0772, ORP2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

TSH3_MOUSE
θ value	0.125558 (rank : 31)	NC score	0.026822 (rank : 98)
Query Neighborhood Hits	142	Target Neighborhood Hits	590	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CGV9, Q5DTX4	Gene names	Tshz3, Kiaa1474, Tsh3, Zfp537, Znf537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

CSKI1_MOUSE
θ value	0.163984 (rank : 32)	NC score	0.022954 (rank : 112)
Query Neighborhood Hits	142	Target Neighborhood Hits	1031	Shared Neighborhood Hits	46
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

LRCH2_MOUSE
θ value	0.163984 (rank : 33)	NC score	0.018317 (rank : 122)
Query Neighborhood Hits	142	Target Neighborhood Hits	287	Shared Neighborhood Hits	5
SwissProt Accessions	Q3UMG5, Q7TNP9, Q80TC9	Gene names	Lrch2, Kiaa1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

MAGE1_HUMAN
θ value	0.163984 (rank : 34)	NC score	0.036114 (rank : 79)
Query Neighborhood Hits	142	Target Neighborhood Hits	1389	Shared Neighborhood Hits	58
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

CD248_HUMAN
θ value	0.21417 (rank : 35)	NC score	0.031794 (rank : 91)
Query Neighborhood Hits	142	Target Neighborhood Hits	679	Shared Neighborhood Hits	28
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

ETV6_HUMAN
θ value	0.279714 (rank : 36)	NC score	0.025014 (rank : 104)
Query Neighborhood Hits	142	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	P41212, Q9UMF6	Gene names	ETV6, TEL, TEL1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

RGS3_MOUSE
θ value	0.279714 (rank : 37)	NC score	0.043998 (rank : 71)
Query Neighborhood Hits	142	Target Neighborhood Hits	1621	Shared Neighborhood Hits	57
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

GRIN1_HUMAN
θ value	0.365318 (rank : 38)	NC score	0.036052 (rank : 80)
Query Neighborhood Hits	142	Target Neighborhood Hits	681	Shared Neighborhood Hits	38
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

ZN667_HUMAN
θ value	0.47712 (rank : 39)	NC score	0.002917 (rank : 180)
Query Neighborhood Hits	142	Target Neighborhood Hits	773	Shared Neighborhood Hits	12
SwissProt Accessions	Q5HYK9, Q6B093, Q9H807	Gene names	ZNF667
Domain Architecture	No domain graphic available
Description	Zinc finger protein 667.

MFAP1_MOUSE
θ value	0.62314 (rank : 40)	NC score	0.029688 (rank : 95)
Query Neighborhood Hits	142	Target Neighborhood Hits	353	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

MINT_MOUSE
θ value	0.62314 (rank : 41)	NC score	0.029728 (rank : 94)
Query Neighborhood Hits	142	Target Neighborhood Hits	1514	Shared Neighborhood Hits	56
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NFAC1_HUMAN
θ value	0.62314 (rank : 42)	NC score	0.025484 (rank : 102)
Query Neighborhood Hits	142	Target Neighborhood Hits	312	Shared Neighborhood Hits	25
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

SIX4_MOUSE
θ value	0.62314 (rank : 43)	NC score	0.018071 (rank : 123)
Query Neighborhood Hits	142	Target Neighborhood Hits	341	Shared Neighborhood Hits	6
SwissProt Accessions	Q61321, Q61322, Q61323	Gene names	Six4, Arec3
Domain Architecture
Description	Homeobox protein SIX4 (Sine oculis homeobox homolog 4) (Skeletal muscle-specific ARE-binding protein AREC3).

CU024_HUMAN
θ value	0.813845 (rank : 44)	NC score	0.056834 (rank : 54)
Query Neighborhood Hits	142	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q6XXX2	Gene names	C21orf24
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C21orf24.

K1543_HUMAN
θ value	0.813845 (rank : 45)	NC score	0.049820 (rank : 67)
Query Neighborhood Hits	142	Target Neighborhood Hits	435	Shared Neighborhood Hits	34
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

MKL1_MOUSE
θ value	0.813845 (rank : 46)	NC score	0.040671 (rank : 74)
Query Neighborhood Hits	142	Target Neighborhood Hits	667	Shared Neighborhood Hits	30
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

SEPT9_HUMAN
θ value	0.813845 (rank : 47)	NC score	0.024503 (rank : 106)
Query Neighborhood Hits	142	Target Neighborhood Hits	706	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

ZBT17_HUMAN
θ value	0.813845 (rank : 48)	NC score	0.004318 (rank : 175)
Query Neighborhood Hits	142	Target Neighborhood Hits	925	Shared Neighborhood Hits	14
SwissProt Accessions	Q13105, Q15932, Q5JYB2, Q9NUC9	Gene names	ZBTB17, MIZ1, ZNF151
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 17 (Zinc finger protein 151) (Myc-interacting zinc finger protein) (Miz-1 protein).

ENPL_HUMAN
θ value	1.06291 (rank : 49)	NC score	0.017613 (rank : 126)
Query Neighborhood Hits	142	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	P14625, Q96A97	Gene names	HSP90B1, TRA1
Domain Architecture
Description	Endoplasmin precursor (Heat shock protein 90 kDa beta member 1) (94 kDa glucose-regulated protein) (GRP94) (gp96 homolog) (Tumor rejection antigen 1).

ERCC5_MOUSE
θ value	1.06291 (rank : 50)	NC score	0.032716 (rank : 89)
Query Neighborhood Hits	142	Target Neighborhood Hits	206	Shared Neighborhood Hits	11
SwissProt Accessions	P35689, Q61528, Q64248	Gene names	Ercc5, Ercc-5, Xpg
Domain Architecture
Description	DNA-repair protein complementing XP-G cells homolog (Xeroderma pigmentosum group G-complementing protein homolog) (DNA excision repair protein ERCC-5).

FGD3_HUMAN
θ value	1.06291 (rank : 51)	NC score	0.010288 (rank : 152)
Query Neighborhood Hits	142	Target Neighborhood Hits	249	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

NALDL_MOUSE
θ value	1.06291 (rank : 52)	NC score	0.018471 (rank : 121)
Query Neighborhood Hits	142	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q7M758	Gene names	Naaladl1, Naaladasel
Domain Architecture	No domain graphic available
Description	N-acetylated-alpha-linked acidic dipeptidase-like protein (EC 3.4.17.21) (NAALADase L).

SRRM1_MOUSE
θ value	1.06291 (rank : 53)	NC score	0.046968 (rank : 68)
Query Neighborhood Hits	142	Target Neighborhood Hits	966	Shared Neighborhood Hits	49
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

BAZ2A_MOUSE
θ value	1.38821 (rank : 54)	NC score	0.021124 (rank : 117)
Query Neighborhood Hits	142	Target Neighborhood Hits	744	Shared Neighborhood Hits	34
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BPAEA_HUMAN
θ value	1.38821 (rank : 55)	NC score	0.008850 (rank : 159)
Query Neighborhood Hits	142	Target Neighborhood Hits	1369	Shared Neighborhood Hits	20
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

F100B_MOUSE
θ value	1.38821 (rank : 56)	NC score	0.044286 (rank : 70)
Query Neighborhood Hits	142	Target Neighborhood Hits	91	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BQH4, Q3UMH5	Gene names	Fam100b
Domain Architecture	No domain graphic available
Description	Protein FAM100B.

NF2L1_HUMAN
θ value	1.38821 (rank : 57)	NC score	0.016998 (rank : 128)
Query Neighborhood Hits	142	Target Neighborhood Hits	169	Shared Neighborhood Hits	5
SwissProt Accessions	Q14494, Q12877, Q96FN6	Gene names	NFE2L1, HBZ17, NRF1, TCF11
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1) (Transcription factor 11) (Transcription factor HBZ17) (Transcription factor LCR-F1) (Locus control region-factor 1).

SC24C_HUMAN
θ value	1.38821 (rank : 58)	NC score	0.031476 (rank : 92)
Query Neighborhood Hits	142	Target Neighborhood Hits	662	Shared Neighborhood Hits	30
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

TM108_MOUSE
θ value	1.38821 (rank : 59)	NC score	0.034632 (rank : 84)
Query Neighborhood Hits	142	Target Neighborhood Hits	336	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

ZN509_MOUSE
θ value	1.38821 (rank : 60)	NC score	0.003700 (rank : 179)
Query Neighborhood Hits	142	Target Neighborhood Hits	990	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

BAT3_HUMAN
θ value	1.81305 (rank : 61)	NC score	0.041399 (rank : 72)
Query Neighborhood Hits	142	Target Neighborhood Hits	490	Shared Neighborhood Hits	31
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BAT3_MOUSE
θ value	1.81305 (rank : 62)	NC score	0.046232 (rank : 69)
Query Neighborhood Hits	142	Target Neighborhood Hits	518	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

BCL6_HUMAN
θ value	1.81305 (rank : 63)	NC score	0.003920 (rank : 177)
Query Neighborhood Hits	142	Target Neighborhood Hits	922	Shared Neighborhood Hits	21
SwissProt Accessions	P41182	Gene names	BCL6, BCL5, LAZ3, ZBTB27, ZNF51
Domain Architecture
Description	B-cell lymphoma 6 protein (BCL-6) (Zinc finger protein 51) (LAZ-3 protein) (BCL-5) (Zinc finger and BTB domain-containing protein 27).

IWS1_HUMAN
θ value	1.81305 (rank : 64)	NC score	0.023229 (rank : 111)
Query Neighborhood Hits	142	Target Neighborhood Hits	1241	Shared Neighborhood Hits	41
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

K1802_MOUSE
θ value	1.81305 (rank : 65)	NC score	0.038835 (rank : 77)
Query Neighborhood Hits	142	Target Neighborhood Hits	1596	Shared Neighborhood Hits	65
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MLL3_HUMAN
θ value	1.81305 (rank : 66)	NC score	0.033915 (rank : 85)
Query Neighborhood Hits	142	Target Neighborhood Hits	1644	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

P66A_MOUSE
θ value	1.81305 (rank : 67)	NC score	0.022293 (rank : 115)
Query Neighborhood Hits	142	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CHY6, Q8BTQ2, Q8VEC9	Gene names	Gatad2a
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 alpha (GATA zinc finger domain- containing protein 2A).

TAU_HUMAN
θ value	1.81305 (rank : 68)	NC score	0.033358 (rank : 87)
Query Neighborhood Hits	142	Target Neighborhood Hits	448	Shared Neighborhood Hits	31
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

ZN688_HUMAN
θ value	1.81305 (rank : 69)	NC score	0.003738 (rank : 178)
Query Neighborhood Hits	142	Target Neighborhood Hits	873	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WV14, O75701, Q8IW91, Q96MN0	Gene names	ZNF688
Domain Architecture	No domain graphic available
Description	Zinc finger protein 688.

CF010_HUMAN
θ value	2.36792 (rank : 70)	NC score	0.021378 (rank : 116)
Query Neighborhood Hits	142	Target Neighborhood Hits	329	Shared Neighborhood Hits	9
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

MILK1_MOUSE
θ value	2.36792 (rank : 71)	NC score	0.035013 (rank : 82)
Query Neighborhood Hits	142	Target Neighborhood Hits	788	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MK15_HUMAN
θ value	2.36792 (rank : 72)	NC score	-0.001318 (rank : 183)
Query Neighborhood Hits	142	Target Neighborhood Hits	1038	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

PCDA5_HUMAN
θ value	2.36792 (rank : 73)	NC score	0.002000 (rank : 181)
Query Neighborhood Hits	142	Target Neighborhood Hits	217	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y5H7, O75284, Q8N4R3	Gene names	PCDHA5
Domain Architecture
Description	Protocadherin alpha 5 precursor (PCDH-alpha5).

PER3_HUMAN
θ value	2.36792 (rank : 74)	NC score	0.023353 (rank : 109)
Query Neighborhood Hits	142	Target Neighborhood Hits	479	Shared Neighborhood Hits	30
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

RC3H1_HUMAN
θ value	2.36792 (rank : 75)	NC score	0.014310 (rank : 136)
Query Neighborhood Hits	142	Target Neighborhood Hits	433	Shared Neighborhood Hits	11
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

TE2IP_HUMAN
θ value	2.36792 (rank : 76)	NC score	0.032799 (rank : 88)
Query Neighborhood Hits	142	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NYB0, Q8WYZ3, Q9NWR2	Gene names	TERF2IP, RAP1
Domain Architecture	No domain graphic available
Description	Telomeric repeat-binding factor 2-interacting protein 1 (TRF2- interacting telomeric protein Rap1) (hRap1).

TE2IP_MOUSE
θ value	2.36792 (rank : 77)	NC score	0.033397 (rank : 86)
Query Neighborhood Hits	142	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	Q91VL8, Q543F4, Q9JJE8, Q9JJE9	Gene names	Terf2ip, Rap1
Domain Architecture	No domain graphic available
Description	Telomeric repeat-binding factor 2-interacting protein 1 (TRF2- interacting telomeric protein Rap1).

CAC1B_MOUSE
θ value	3.0926 (rank : 78)	NC score	0.008006 (rank : 163)
Query Neighborhood Hits	142	Target Neighborhood Hits	351	Shared Neighborhood Hits	20
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CEBPE_HUMAN
θ value	3.0926 (rank : 79)	NC score	0.016027 (rank : 132)
Query Neighborhood Hits	142	Target Neighborhood Hits	236	Shared Neighborhood Hits	5
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

CTND2_HUMAN
θ value	3.0926 (rank : 80)	NC score	0.017977 (rank : 124)
Query Neighborhood Hits	142	Target Neighborhood Hits	333	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

FOXM1_HUMAN
θ value	3.0926 (rank : 81)	NC score	0.011562 (rank : 145)
Query Neighborhood Hits	142	Target Neighborhood Hits	167	Shared Neighborhood Hits	14
SwissProt Accessions	Q08050, O43258, O43259, O43260, Q4ZGG7, Q9BRL2	Gene names	FOXM1, FKHL16, HFH11, MPP2, WIN
Domain Architecture
Description	Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/fork-head homolog 11) (HFH-11) (Winged helix factor from INS-1 cells) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident).

FRS3_MOUSE
θ value	3.0926 (rank : 82)	NC score	0.015806 (rank : 134)
Query Neighborhood Hits	142	Target Neighborhood Hits	168	Shared Neighborhood Hits	12
SwissProt Accessions	Q91WJ0	Gene names	Frs3, Frs2b
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FRS2-beta).

HAP1_HUMAN
θ value	3.0926 (rank : 83)	NC score	0.012402 (rank : 142)
Query Neighborhood Hits	142	Target Neighborhood Hits	606	Shared Neighborhood Hits	15
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

KPCL_HUMAN
θ value	3.0926 (rank : 84)	NC score	-0.002588 (rank : 184)
Query Neighborhood Hits	142	Target Neighborhood Hits	887	Shared Neighborhood Hits	3
SwissProt Accessions	P24723, Q16246	Gene names	PRKCH, PKCL
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

NPAS4_MOUSE
θ value	3.0926 (rank : 85)	NC score	0.016984 (rank : 129)
Query Neighborhood Hits	142	Target Neighborhood Hits	245	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

SM1L2_HUMAN
θ value	3.0926 (rank : 86)	NC score	0.006496 (rank : 169)
Query Neighborhood Hits	142	Target Neighborhood Hits	1019	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

AL2S8_MOUSE
θ value	4.03905 (rank : 87)	NC score	0.017551 (rank : 127)
Query Neighborhood Hits	142	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VHI4	Gene names	Als2cr8, Carf
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein homolog (Calcium-response factor) (CaRF).

BPA1_MOUSE
θ value	4.03905 (rank : 88)	NC score	0.006821 (rank : 167)
Query Neighborhood Hits	142	Target Neighborhood Hits	1477	Shared Neighborhood Hits	24
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

INOC1_HUMAN
θ value	4.03905 (rank : 89)	NC score	0.010801 (rank : 150)
Query Neighborhood Hits	142	Target Neighborhood Hits	181	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

INOC1_MOUSE
θ value	4.03905 (rank : 90)	NC score	0.010898 (rank : 149)
Query Neighborhood Hits	142	Target Neighborhood Hits	178	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

K1802_HUMAN
θ value	4.03905 (rank : 91)	NC score	0.034763 (rank : 83)
Query Neighborhood Hits	142	Target Neighborhood Hits	1378	Shared Neighborhood Hits	57
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

NKTR_HUMAN
θ value	4.03905 (rank : 92)	NC score	0.009390 (rank : 156)
Query Neighborhood Hits	142	Target Neighborhood Hits	658	Shared Neighborhood Hits	21
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

CC28B_HUMAN
θ value	5.27518 (rank : 93)	NC score	0.022895 (rank : 114)
Query Neighborhood Hits	142	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BUN5, Q8TBV8	Gene names	CCDC28B
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 28B.

CC28B_MOUSE
θ value	5.27518 (rank : 94)	NC score	0.023291 (rank : 110)
Query Neighborhood Hits	142	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CEG5, Q8K132	Gene names	Ccdc28b
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 28B.

DOK3_MOUSE
θ value	5.27518 (rank : 95)	NC score	0.013568 (rank : 139)
Query Neighborhood Hits	142	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZK7	Gene names	Dok3, Dokl
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3) (P62(dok)-like protein) (DOK-L).

HDGR3_HUMAN
θ value	5.27518 (rank : 96)	NC score	0.012296 (rank : 143)
Query Neighborhood Hits	142	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y3E1	Gene names	HDGFRP3, HDGF2
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3) (Hepatoma- derived growth factor 2).

LZTS1_MOUSE
θ value	5.27518 (rank : 97)	NC score	0.011540 (rank : 147)
Query Neighborhood Hits	142	Target Neighborhood Hits	540	Shared Neighborhood Hits	13
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

MDC1_MOUSE
θ value	5.27518 (rank : 98)	NC score	0.027328 (rank : 97)
Query Neighborhood Hits	142	Target Neighborhood Hits	998	Shared Neighborhood Hits	48
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

NADE1_MOUSE
θ value	5.27518 (rank : 99)	NC score	0.014727 (rank : 135)
Query Neighborhood Hits	142	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q711T7, Q711P6, Q8CFY6, Q9D280	Gene names	Nadsyn1
Domain Architecture	No domain graphic available
Description	Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]) (NAD(+) synthetase 1) (NH3-dependent NAD(+) synthetase-like protein).

S3TC2_MOUSE
θ value	5.27518 (rank : 100)	NC score	0.011555 (rank : 146)
Query Neighborhood Hits	142	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	Q80VA5, Q8BWH2, Q8BXB8, Q8C0G6	Gene names	Sh3tc2, Kiaa1985
Domain Architecture
Description	SH3 domain and tetratricopeptide repeats-containing protein 2.

SRRM1_HUMAN
θ value	5.27518 (rank : 101)	NC score	0.037382 (rank : 78)
Query Neighborhood Hits	142	Target Neighborhood Hits	690	Shared Neighborhood Hits	43
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

ZC3H6_HUMAN
θ value	5.27518 (rank : 102)	NC score	0.014104 (rank : 138)
Query Neighborhood Hits	142	Target Neighborhood Hits	228	Shared Neighborhood Hits	18
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

ARI1A_HUMAN
θ value	6.88961 (rank : 103)	NC score	0.023526 (rank : 107)
Query Neighborhood Hits	142	Target Neighborhood Hits	787	Shared Neighborhood Hits	39
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

BCN1_HUMAN
θ value	6.88961 (rank : 104)	NC score	0.009276 (rank : 157)
Query Neighborhood Hits	142	Target Neighborhood Hits	395	Shared Neighborhood Hits	8
SwissProt Accessions	Q14457, O75595, Q9UNA8	Gene names	BECN1, GT197
Domain Architecture
Description	Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197).

BRDT_MOUSE
θ value	6.88961 (rank : 105)	NC score	0.009394 (rank : 155)
Query Neighborhood Hits	142	Target Neighborhood Hits	243	Shared Neighborhood Hits	14
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

BSN_MOUSE
θ value	6.88961 (rank : 106)	NC score	0.035882 (rank : 81)
Query Neighborhood Hits	142	Target Neighborhood Hits	2057	Shared Neighborhood Hits	66
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CD248_MOUSE
θ value	6.88961 (rank : 107)	NC score	0.019676 (rank : 119)
Query Neighborhood Hits	142	Target Neighborhood Hits	578	Shared Neighborhood Hits	22
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

DLGP1_HUMAN
θ value	6.88961 (rank : 108)	NC score	0.008034 (rank : 161)
Query Neighborhood Hits	142	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	O14490, O14489, P78335	Gene names	DLGAP1, DAP1, GKAP
Domain Architecture
Description	Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (hGKAP) (SAP90/PSD-95-associated protein 1) (SAPAP1) (PSD- 95/SAP90-binding protein 1).

DMRTD_HUMAN
θ value	6.88961 (rank : 109)	NC score	0.016512 (rank : 131)
Query Neighborhood Hits	142	Target Neighborhood Hits	216	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

FOXC2_MOUSE
θ value	6.88961 (rank : 110)	NC score	0.004000 (rank : 176)
Query Neighborhood Hits	142	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	Q61850, P97948, Q63869, Q8C694	Gene names	Foxc2, Fkh14, Fkhl14, Mfh1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

GLU2B_HUMAN
θ value	6.88961 (rank : 111)	NC score	0.011470 (rank : 148)
Query Neighborhood Hits	142	Target Neighborhood Hits	377	Shared Neighborhood Hits	10
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

MAP1A_HUMAN
θ value	6.88961 (rank : 112)	NC score	0.019099 (rank : 120)
Query Neighborhood Hits	142	Target Neighborhood Hits	1626	Shared Neighborhood Hits	57
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MTSS1_HUMAN
θ value	6.88961 (rank : 113)	NC score	0.017868 (rank : 125)
Query Neighborhood Hits	142	Target Neighborhood Hits	504	Shared Neighborhood Hits	22
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

MUG2_MOUSE
θ value	6.88961 (rank : 114)	NC score	0.006239 (rank : 170)
Query Neighborhood Hits	142	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	P28666	Gene names	Mug2, Mug-2
Domain Architecture
Description	Murinoglobulin-2 precursor (MuG2).

PI5PA_MOUSE
θ value	6.88961 (rank : 115)	NC score	0.026685 (rank : 99)
Query Neighborhood Hits	142	Target Neighborhood Hits	331	Shared Neighborhood Hits	31
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PRKDC_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.007673 (rank : 165)
Query Neighborhood Hits	142	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3	Gene names	PRKDC
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460).

RBY1A_HUMAN
θ value	6.88961 (rank : 117)	NC score	0.005544 (rank : 171)
Query Neighborhood Hits	142	Target Neighborhood Hits	245	Shared Neighborhood Hits	4
SwissProt Accessions	Q15414, Q15377, Q8NHR0	Gene names	RBMY1A1, RBM1, YRRM1
Domain Architecture
Description	RNA-binding motif protein, Y chromosome, family 1 member A1 (RNA- binding motif protein 1).

RT28_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.016944 (rank : 130)
Query Neighborhood Hits	142	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2Q9, Q96Q21	Gene names	MRPS28, MRPS35
Domain Architecture	No domain graphic available
Description	Mitochondrial 28S ribosomal protein S28 (S28mt) (MRP-S28) (MRP-S35).

SFRS4_HUMAN
θ value	6.88961 (rank : 119)	NC score	0.007389 (rank : 166)
Query Neighborhood Hits	142	Target Neighborhood Hits	384	Shared Neighborhood Hits	12
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

SMOO_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.025143 (rank : 103)
Query Neighborhood Hits	142	Target Neighborhood Hits	391	Shared Neighborhood Hits	34
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

ARI4A_HUMAN
θ value	8.99809 (rank : 121)	NC score	0.012693 (rank : 141)
Query Neighborhood Hits	142	Target Neighborhood Hits	434	Shared Neighborhood Hits	12
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

BAG3_MOUSE
θ value	8.99809 (rank : 122)	NC score	0.030973 (rank : 93)
Query Neighborhood Hits	142	Target Neighborhood Hits	513	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BCL9_HUMAN
θ value	8.99809 (rank : 123)	NC score	0.032502 (rank : 90)
Query Neighborhood Hits	142	Target Neighborhood Hits	1008	Shared Neighborhood Hits	45
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CUTL1_HUMAN
θ value	8.99809 (rank : 124)	NC score	0.014203 (rank : 137)
Query Neighborhood Hits	142	Target Neighborhood Hits	1574	Shared Neighborhood Hits	36
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

DDX51_HUMAN
θ value	8.99809 (rank : 125)	NC score	0.008022 (rank : 162)
Query Neighborhood Hits	142	Target Neighborhood Hits	332	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

GNAS1_HUMAN
θ value	8.99809 (rank : 126)	NC score	0.008930 (rank : 158)
Query Neighborhood Hits	142	Target Neighborhood Hits	278	Shared Neighborhood Hits	21
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

LPP_HUMAN
θ value	8.99809 (rank : 127)	NC score	0.012934 (rank : 140)
Query Neighborhood Hits	142	Target Neighborhood Hits	775	Shared Neighborhood Hits	31
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

LRCH2_HUMAN
θ value	8.99809 (rank : 128)	NC score	0.009987 (rank : 153)
Query Neighborhood Hits	142	Target Neighborhood Hits	315	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VUJ6, Q9HA88, Q9P233	Gene names	LRCH2, KIAA1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

MCP_MOUSE
θ value	8.99809 (rank : 129)	NC score	0.004787 (rank : 173)
Query Neighborhood Hits	142	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	O88174, Q9R0R9	Gene names	Cd46, Mcp
Domain Architecture	No domain graphic available
Description	Membrane cofactor protein precursor (CD46 antigen).

MEF2D_HUMAN
θ value	8.99809 (rank : 130)	NC score	0.008740 (rank : 160)
Query Neighborhood Hits	142	Target Neighborhood Hits	170	Shared Neighborhood Hits	13
SwissProt Accessions	Q14814, Q14815	Gene names	MEF2D
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

MFAP1_HUMAN
θ value	8.99809 (rank : 131)	NC score	0.020369 (rank : 118)
Query Neighborhood Hits	142	Target Neighborhood Hits	321	Shared Neighborhood Hits	11
SwissProt Accessions	P55081	Gene names	MFAP1
Domain Architecture
Description	Microfibrillar-associated protein 1.

PARD3_HUMAN
θ value	8.99809 (rank : 132)	NC score	0.004321 (rank : 174)
Query Neighborhood Hits	142	Target Neighborhood Hits	312	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PCLO_MOUSE
θ value	8.99809 (rank : 133)	NC score	0.024870 (rank : 105)
Query Neighborhood Hits	142	Target Neighborhood Hits	2275	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RNPL1_HUMAN
θ value	8.99809 (rank : 134)	NC score	0.006540 (rank : 168)
Query Neighborhood Hits	142	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HAU8, Q96AC9, Q9H033, Q9NVD0	Gene names	RNPEPL1
Domain Architecture
Description	Arginyl aminopeptidase-like 1 (EC 3.4.11.-) (RNPEP-like protein).

SGOL2_MOUSE
θ value	8.99809 (rank : 135)	NC score	0.009858 (rank : 154)
Query Neighborhood Hits	142	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TSY8, Q811I4, Q8C9C4, Q8CGJ4, Q9CS55	Gene names	Sgol2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2.

SRRM2_HUMAN
θ value	8.99809 (rank : 136)	NC score	0.029002 (rank : 96)
Query Neighborhood Hits	142	Target Neighborhood Hits	1296	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SYF2_MOUSE
θ value	8.99809 (rank : 137)	NC score	0.012199 (rank : 144)
Query Neighborhood Hits	142	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D198	Gene names	Syf2, Cbpin, Gcipip
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor SYF2 (CCNDBP1-interactor) (p29) (mp29).

TACC2_MOUSE
θ value	8.99809 (rank : 138)	NC score	0.010673 (rank : 151)
Query Neighborhood Hits	142	Target Neighborhood Hits	774	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TARA_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.039278 (rank : 76)
Query Neighborhood Hits	142	Target Neighborhood Hits	1626	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TS13_MOUSE
θ value	8.99809 (rank : 140)	NC score	0.015809 (rank : 133)
Query Neighborhood Hits	142	Target Neighborhood Hits	191	Shared Neighborhood Hits	13
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

YTHD2_HUMAN
θ value	8.99809 (rank : 141)	NC score	0.007698 (rank : 164)
Query Neighborhood Hits	142	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y5A9, Q5VSZ9, Q8TDH0, Q9BUJ5	Gene names	YTHDF2, HGRG8
Domain Architecture
Description	YTH domain family protein 2 (High-glucose-regulated protein 8) (NY- REN-2 antigen) (CLL-associated antigen KW-14).

ZN621_HUMAN
θ value	8.99809 (rank : 142)	NC score	0.001567 (rank : 182)
Query Neighborhood Hits	142	Target Neighborhood Hits	737	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZSS3, Q8TE91	Gene names	ZNF621
Domain Architecture	No domain graphic available
Description	Zinc finger protein 621.

3BP2_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.111470 (rank : 36)
Query Neighborhood Hits	142	Target Neighborhood Hits	296	Shared Neighborhood Hits	19
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

3BP2_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.112613 (rank : 35)
Query Neighborhood Hits	142	Target Neighborhood Hits	142	Shared Neighborhood Hits	12
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

AB1IP_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.054722 (rank : 59)
Query Neighborhood Hits	142	Target Neighborhood Hits	213	Shared Neighborhood Hits	33
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

ANLN_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.115852 (rank : 33)
Query Neighborhood Hits	142	Target Neighborhood Hits	222	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

ANLN_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.094305 (rank : 44)
Query Neighborhood Hits	142	Target Neighborhood Hits	297	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

CENB2_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.066065 (rank : 49)
Query Neighborhood Hits	142	Target Neighborhood Hits	425	Shared Neighborhood Hits	12
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB5_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.060317 (rank : 51)
Query Neighborhood Hits	142	Target Neighborhood Hits	395	Shared Neighborhood Hits	13
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CNKR1_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.192006 (rank : 23)
Query Neighborhood Hits	142	Target Neighborhood Hits	154	Shared Neighborhood Hits	18
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CNKR2_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.097952 (rank : 42)
Query Neighborhood Hits	142	Target Neighborhood Hits	197	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.098038 (rank : 41)
Query Neighborhood Hits	142	Target Neighborhood Hits	197	Shared Neighborhood Hits	12
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

DAPP1_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.109210 (rank : 37)
Query Neighborhood Hits	142	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.114917 (rank : 34)
Query Neighborhood Hits	142	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DYN2_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.056489 (rank : 55)
Query Neighborhood Hits	142	Target Neighborhood Hits	112	Shared Neighborhood Hits	17
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

DYN2_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.055731 (rank : 57)
Query Neighborhood Hits	142	Target Neighborhood Hits	104	Shared Neighborhood Hits	15
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

DYN3_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.058854 (rank : 52)
Query Neighborhood Hits	142	Target Neighborhood Hits	158	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

GNRP_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.056993 (rank : 53)
Query Neighborhood Hits	142	Target Neighborhood Hits	239	Shared Neighborhood Hits	13
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

GNRP_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.054064 (rank : 61)
Query Neighborhood Hits	142	Target Neighborhood Hits	191	Shared Neighborhood Hits	12
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

MTMR5_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.053140 (rank : 62)
Query Neighborhood Hits	142	Target Neighborhood Hits	141	Shared Neighborhood Hits	9
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

OSBL8_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.053091 (rank : 63)
Query Neighborhood Hits	142	Target Neighborhood Hits	289	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

PHLB1_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.051230 (rank : 66)
Query Neighborhood Hits	142	Target Neighborhood Hits	1038	Shared Neighborhood Hits	46
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PKHA1_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.133234 (rank : 26)
Query Neighborhood Hits	142	Target Neighborhood Hits	127	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.132768 (rank : 27)
Query Neighborhood Hits	142	Target Neighborhood Hits	120	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA2_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.104431 (rank : 38)
Query Neighborhood Hits	142	Target Neighborhood Hits	119	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PKHA2_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.118445 (rank : 32)
Query Neighborhood Hits	142	Target Neighborhood Hits	116	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PKHA4_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.118900 (rank : 31)
Query Neighborhood Hits	142	Target Neighborhood Hits	283	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA4_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.123373 (rank : 30)
Query Neighborhood Hits	142	Target Neighborhood Hits	202	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA5_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.096758 (rank : 43)
Query Neighborhood Hits	142	Target Neighborhood Hits	455	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PKHA6_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.136106 (rank : 24)
Query Neighborhood Hits	142	Target Neighborhood Hits	556	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.130300 (rank : 29)
Query Neighborhood Hits	142	Target Neighborhood Hits	591	Shared Neighborhood Hits	29
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHB1_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.051348 (rank : 65)
Query Neighborhood Hits	142	Target Neighborhood Hits	46	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UF11, Q9UBF5, Q9UI37, Q9UI44	Gene names	PLEKHB1, KPL1, PHR1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

PKHB2_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.056318 (rank : 56)
Query Neighborhood Hits	142	Target Neighborhood Hits	54	Shared Neighborhood Hits	10
SwissProt Accessions	Q96CS7, Q86W37, Q9BV75, Q9NWK1	Gene names	PLEKHB2, EVT2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

PKHB2_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.054867 (rank : 58)
Query Neighborhood Hits	142	Target Neighborhood Hits	48	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QZC7, Q3UDH6, Q8C4I4, Q8CA27	Gene names	Plekhb2, Evt2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

PLEK2_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.099184 (rank : 40)
Query Neighborhood Hits	142	Target Neighborhood Hits	101	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.101095 (rank : 39)
Query Neighborhood Hits	142	Target Neighborhood Hits	96	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PLEK_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.130642 (rank : 28)
Query Neighborhood Hits	142	Target Neighborhood Hits	110	Shared Neighborhood Hits	11
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PLEK_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.133417 (rank : 25)
Query Neighborhood Hits	142	Target Neighborhood Hits	109	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

RASA1_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.077785 (rank : 45)
Query Neighborhood Hits	142	Target Neighborhood Hits	258	Shared Neighborhood Hits	8
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RHG25_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.073744 (rank : 47)
Query Neighborhood Hits	142	Target Neighborhood Hits	550	Shared Neighborhood Hits	17
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.077066 (rank : 46)
Query Neighborhood Hits	142	Target Neighborhood Hits	492	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SWP70_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.068988 (rank : 48)
Query Neighborhood Hits	142	Target Neighborhood Hits	973	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.060496 (rank : 50)
Query Neighborhood Hits	142	Target Neighborhood Hits	1097	Shared Neighborhood Hits	23
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

TBCD2_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.051916 (rank : 64)
Query Neighborhood Hits	142	Target Neighborhood Hits	419	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

Hits sorted by NC score

GBF1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	142	Target Neighborhood Hits	142	Shared Neighborhood Hits	142
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

BIG1_HUMAN
NC score	0.869742 (rank : 2)	θ value	3.59435e-57 (rank : 3)
Query Neighborhood Hits	142	Target Neighborhood Hits	76	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

BIG2_HUMAN
NC score	0.868836 (rank : 3)	θ value	4.10295e-61 (rank : 2)
Query Neighborhood Hits	142	Target Neighborhood Hits	66	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

IQEC3_HUMAN
NC score	0.824317 (rank : 4)	θ value	1.85889e-29 (rank : 16)
Query Neighborhood Hits	142	Target Neighborhood Hits	125	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IQEC1_MOUSE
NC score	0.821060 (rank : 5)	θ value	5.22648e-32 (rank : 13)
Query Neighborhood Hits	142	Target Neighborhood Hits	54	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R0S2, Q3TZC3, Q5DU15	Gene names	Iqsec1, Kiaa0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1.

IQEC3_MOUSE
NC score	0.819649 (rank : 6)	θ value	1.85889e-29 (rank : 17)
Query Neighborhood Hits	142	Target Neighborhood Hits	274	Shared Neighborhood Hits	45
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IQEC1_HUMAN
NC score	0.818949 (rank : 7)	θ value	5.22648e-32 (rank : 12)
Query Neighborhood Hits	142	Target Neighborhood Hits	76	Shared Neighborhood Hits	24
SwissProt Accessions	Q6DN90, O94863, Q96D85	Gene names	IQSEC1, ARFGEP100, BRAG2, KIAA0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein).

CYH2_MOUSE
NC score	0.813468 (rank : 8)	θ value	6.59618e-35 (rank : 8)
Query Neighborhood Hits	142	Target Neighborhood Hits	171	Shared Neighborhood Hits	23
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH3_HUMAN
NC score	0.813035 (rank : 9)	θ value	9.20422e-37 (rank : 4)
Query Neighborhood Hits	142	Target Neighborhood Hits	137	Shared Neighborhood Hits	23
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH2_HUMAN
NC score	0.812975 (rank : 10)	θ value	2.50655e-34 (rank : 9)
Query Neighborhood Hits	142	Target Neighborhood Hits	175	Shared Neighborhood Hits	23
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH4_MOUSE
NC score	0.810636 (rank : 11)	θ value	1.6247e-33 (rank : 10)
Query Neighborhood Hits	142	Target Neighborhood Hits	134	Shared Neighborhood Hits	23
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

CYH1_MOUSE
NC score	0.810310 (rank : 12)	θ value	7.79185e-36 (rank : 7)
Query Neighborhood Hits	142	Target Neighborhood Hits	176	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH4_HUMAN
NC score	0.810015 (rank : 13)	θ value	4.72714e-33 (rank : 11)
Query Neighborhood Hits	142	Target Neighborhood Hits	135	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

CYH1_HUMAN
NC score	0.808090 (rank : 14)	θ value	7.79185e-36 (rank : 6)
Query Neighborhood Hits	142	Target Neighborhood Hits	184	Shared Neighborhood Hits	23
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH3_MOUSE
NC score	0.807238 (rank : 15)	θ value	9.20422e-37 (rank : 5)
Query Neighborhood Hits	142	Target Neighborhood Hits	148	Shared Neighborhood Hits	23
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

IQEC2_MOUSE
NC score	0.782323 (rank : 16)	θ value	4.42448e-31 (rank : 14)
Query Neighborhood Hits	142	Target Neighborhood Hits	417	Shared Neighborhood Hits	50
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_HUMAN
NC score	0.781531 (rank : 17)	θ value	9.8567e-31 (rank : 15)
Query Neighborhood Hits	142	Target Neighborhood Hits	403	Shared Neighborhood Hits	48
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

PSD3_HUMAN
NC score	0.755649 (rank : 18)	θ value	1.5773e-20 (rank : 18)
Query Neighborhood Hits	142	Target Neighborhood Hits	75	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NYI0, Q9Y2F1	Gene names	PSD3, EFA6R, HCA67, KIAA0942
Domain Architecture
Description	PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).

PSD4_MOUSE
NC score	0.720633 (rank : 19)	θ value	3.28887e-18 (rank : 19)
Query Neighborhood Hits	142	Target Neighborhood Hits	78	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44	Gene names	Psd4
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).

FBX8_MOUSE
NC score	0.715186 (rank : 20)	θ value	5.26297e-08 (rank : 21)
Query Neighborhood Hits	142	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QZN3	Gene names	Fbxo8, Fbx8
Domain Architecture
Description	F-box only protein 8.

PSD4_HUMAN
NC score	0.714305 (rank : 21)	θ value	3.63628e-17 (rank : 20)
Query Neighborhood Hits	142	Target Neighborhood Hits	178	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

FBX8_HUMAN
NC score	0.712496 (rank : 22)	θ value	8.97725e-08 (rank : 22)
Query Neighborhood Hits	142	Target Neighborhood Hits	44	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NRD0, Q6UWN4, Q9NRP5, Q9UKC4	Gene names	FBXO8, FBS, FBX8
Domain Architecture
Description	F-box only protein 8 (F-box/SEC7 protein FBS).

CNKR1_HUMAN
NC score	0.192006 (rank : 23)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	142	Target Neighborhood Hits	154	Shared Neighborhood Hits	18
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

PKHA6_HUMAN
NC score	0.136106 (rank : 24)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	142	Target Neighborhood Hits	556	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PLEK_MOUSE
NC score	0.133417 (rank : 25)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	142	Target Neighborhood Hits	109	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

PKHA1_HUMAN
NC score	0.133234 (rank : 26)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	142	Target Neighborhood Hits	127	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_MOUSE
NC score	0.132768 (rank : 27)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	142	Target Neighborhood Hits	120	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PLEK_HUMAN
NC score	0.130642 (rank : 28)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	142	Target Neighborhood Hits	110	Shared Neighborhood Hits	11
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PKHA6_MOUSE
NC score	0.130300 (rank : 29)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	142	Target Neighborhood Hits	591	Shared Neighborhood Hits	29
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA4_MOUSE
NC score	0.123373 (rank : 30)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	142	Target Neighborhood Hits	202	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA4_HUMAN
NC score	0.118900 (rank : 31)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	142	Target Neighborhood Hits	283	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA2_MOUSE
NC score	0.118445 (rank : 32)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	142	Target Neighborhood Hits	116	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

ANLN_HUMAN
NC score	0.115852 (rank : 33)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	142	Target Neighborhood Hits	222	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

DAPP1_MOUSE
NC score	0.114917 (rank : 34)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	142	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

3BP2_MOUSE
NC score	0.112613 (rank : 35)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	142	Target Neighborhood Hits	142	Shared Neighborhood Hits	12
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

3BP2_HUMAN
NC score	0.111470 (rank : 36)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	142	Target Neighborhood Hits	296	Shared Neighborhood Hits	19
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

DAPP1_HUMAN
NC score	0.109210 (rank : 37)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	142	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

PKHA2_HUMAN
NC score	0.104431 (rank : 38)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	142	Target Neighborhood Hits	119	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PLEK2_MOUSE
NC score	0.101095 (rank : 39)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	142	Target Neighborhood Hits	96	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_HUMAN
NC score	0.099184 (rank : 40)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	142	Target Neighborhood Hits	101	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

CNKR2_MOUSE
NC score	0.098038 (rank : 41)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	142	Target Neighborhood Hits	197	Shared Neighborhood Hits	12
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.097952 (rank : 42)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	142	Target Neighborhood Hits	197	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

PKHA5_HUMAN
NC score	0.096758 (rank : 43)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	142	Target Neighborhood Hits	455	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

ANLN_MOUSE
NC score	0.094305 (rank : 44)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	142	Target Neighborhood Hits	297	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

RASA1_HUMAN
NC score	0.077785 (rank : 45)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	142	Target Neighborhood Hits	258	Shared Neighborhood Hits	8
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RHG25_MOUSE
NC score	0.077066 (rank : 46)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	142	Target Neighborhood Hits	492	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_HUMAN
NC score	0.073744 (rank : 47)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	142	Target Neighborhood Hits	550	Shared Neighborhood Hits	17
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SWP70_HUMAN
NC score	0.068988 (rank : 48)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	142	Target Neighborhood Hits	973	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

CENB2_HUMAN
NC score	0.066065 (rank : 49)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	142	Target Neighborhood Hits	425	Shared Neighborhood Hits	12
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

SWP70_MOUSE
NC score	0.060496 (rank : 50)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	142	Target Neighborhood Hits	1097	Shared Neighborhood Hits	23
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

CENB5_HUMAN
NC score	0.060317 (rank : 51)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	142	Target Neighborhood Hits	395	Shared Neighborhood Hits	13
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

DYN3_HUMAN
NC score	0.058854 (rank : 52)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	142	Target Neighborhood Hits	158	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

GNRP_HUMAN
NC score	0.056993 (rank : 53)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	142	Target Neighborhood Hits	239	Shared Neighborhood Hits	13
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

CU024_HUMAN
NC score	0.056834 (rank : 54)	θ value	0.813845 (rank : 44)
Query Neighborhood Hits	142	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q6XXX2	Gene names	C21orf24
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C21orf24.

DYN2_HUMAN
NC score	0.056489 (rank : 55)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	142	Target Neighborhood Hits	112	Shared Neighborhood Hits	17
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

PKHB2_HUMAN
NC score	0.056318 (rank : 56)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	142	Target Neighborhood Hits	54	Shared Neighborhood Hits	10
SwissProt Accessions	Q96CS7, Q86W37, Q9BV75, Q9NWK1	Gene names	PLEKHB2, EVT2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

DYN2_MOUSE
NC score	0.055731 (rank : 57)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	142	Target Neighborhood Hits	104	Shared Neighborhood Hits	15
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

PKHB2_MOUSE
NC score	0.054867 (rank : 58)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	142	Target Neighborhood Hits	48	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QZC7, Q3UDH6, Q8C4I4, Q8CA27	Gene names	Plekhb2, Evt2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

AB1IP_HUMAN
NC score	0.054722 (rank : 59)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	142	Target Neighborhood Hits	213	Shared Neighborhood Hits	33
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

OGFR_HUMAN
NC score	0.054628 (rank : 60)	θ value	0.0113563 (rank : 24)
Query Neighborhood Hits	142	Target Neighborhood Hits	1582	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

GNRP_MOUSE
NC score	0.054064 (rank : 61)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	142	Target Neighborhood Hits	191	Shared Neighborhood Hits	12
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

MTMR5_HUMAN
NC score	0.053140 (rank : 62)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	142	Target Neighborhood Hits	141	Shared Neighborhood Hits	9
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

OSBL8_HUMAN
NC score	0.053091 (rank : 63)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	142	Target Neighborhood Hits	289	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

TBCD2_HUMAN
NC score	0.051916 (rank : 64)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	142	Target Neighborhood Hits	419	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

PKHB1_HUMAN
NC score	0.051348 (rank : 65)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	142	Target Neighborhood Hits	46	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UF11, Q9UBF5, Q9UI37, Q9UI44	Gene names	PLEKHB1, KPL1, PHR1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

PHLB1_HUMAN
NC score	0.051230 (rank : 66)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	142	Target Neighborhood Hits	1038	Shared Neighborhood Hits	46
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

K1543_HUMAN
NC score	0.049820 (rank : 67)	θ value	0.813845 (rank : 45)
Query Neighborhood Hits	142	Target Neighborhood Hits	435	Shared Neighborhood Hits	34
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

SRRM1_MOUSE
NC score	0.046968 (rank : 68)	θ value	1.06291 (rank : 53)
Query Neighborhood Hits	142	Target Neighborhood Hits	966	Shared Neighborhood Hits	49
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

BAT3_MOUSE
NC score	0.046232 (rank : 69)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	142	Target Neighborhood Hits	518	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

F100B_MOUSE
NC score	0.044286 (rank : 70)	θ value	1.38821 (rank : 56)
Query Neighborhood Hits	142	Target Neighborhood Hits	91	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BQH4, Q3UMH5	Gene names	Fam100b
Domain Architecture	No domain graphic available
Description	Protein FAM100B.

RGS3_MOUSE
NC score	0.043998 (rank : 71)	θ value	0.279714 (rank : 37)
Query Neighborhood Hits	142	Target Neighborhood Hits	1621	Shared Neighborhood Hits	57
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

BAT3_HUMAN
NC score	0.041399 (rank : 72)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	142	Target Neighborhood Hits	490	Shared Neighborhood Hits	31
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

RGS3_HUMAN
NC score	0.040852 (rank : 73)	θ value	0.0961366 (rank : 28)
Query Neighborhood Hits	142	Target Neighborhood Hits	1375	Shared Neighborhood Hits	51
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

MKL1_MOUSE
NC score	0.040671 (rank : 74)	θ value	0.813845 (rank : 46)
Query Neighborhood Hits	142	Target Neighborhood Hits	667	Shared Neighborhood Hits	30
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

SON_HUMAN
NC score	0.040095 (rank : 75)	θ value	0.0736092 (rank : 27)
Query Neighborhood Hits	142	Target Neighborhood Hits	1568	Shared Neighborhood Hits	60
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TARA_HUMAN
NC score	0.039278 (rank : 76)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	142	Target Neighborhood Hits	1626	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

K1802_MOUSE
NC score	0.038835 (rank : 77)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	142	Target Neighborhood Hits	1596	Shared Neighborhood Hits	65
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

SRRM1_HUMAN
NC score	0.037382 (rank : 78)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	142	Target Neighborhood Hits	690	Shared Neighborhood Hits	43
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

MAGE1_HUMAN
NC score	0.036114 (rank : 79)	θ value	0.163984 (rank : 34)
Query Neighborhood Hits	142	Target Neighborhood Hits	1389	Shared Neighborhood Hits	58
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

GRIN1_HUMAN
NC score	0.036052 (rank : 80)	θ value	0.365318 (rank : 38)
Query Neighborhood Hits	142	Target Neighborhood Hits	681	Shared Neighborhood Hits	38
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

BSN_MOUSE
NC score	0.035882 (rank : 81)	θ value	6.88961 (rank : 106)
Query Neighborhood Hits	142	Target Neighborhood Hits	2057	Shared Neighborhood Hits	66
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MILK1_MOUSE
NC score	0.035013 (rank : 82)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	142	Target Neighborhood Hits	788	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

K1802_HUMAN
NC score	0.034763 (rank : 83)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	142	Target Neighborhood Hits	1378	Shared Neighborhood Hits	57
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

TM108_MOUSE
NC score	0.034632 (rank : 84)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	142	Target Neighborhood Hits	336	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

MLL3_HUMAN
NC score	0.033915 (rank : 85)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	142	Target Neighborhood Hits	1644	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

TE2IP_MOUSE
NC score	0.033397 (rank : 86)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	142	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	Q91VL8, Q543F4, Q9JJE8, Q9JJE9	Gene names	Terf2ip, Rap1
Domain Architecture	No domain graphic available
Description	Telomeric repeat-binding factor 2-interacting protein 1 (TRF2- interacting telomeric protein Rap1).

TAU_HUMAN
NC score	0.033358 (rank : 87)	θ value	1.81305 (rank : 68)
Query Neighborhood Hits	142	Target Neighborhood Hits	448	Shared Neighborhood Hits	31
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TE2IP_HUMAN
NC score	0.032799 (rank : 88)	θ value	2.36792 (rank : 76)
Query Neighborhood Hits	142	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NYB0, Q8WYZ3, Q9NWR2	Gene names	TERF2IP, RAP1
Domain Architecture	No domain graphic available
Description	Telomeric repeat-binding factor 2-interacting protein 1 (TRF2- interacting telomeric protein Rap1) (hRap1).

ERCC5_MOUSE
NC score	0.032716 (rank : 89)	θ value	1.06291 (rank : 50)
Query Neighborhood Hits	142	Target Neighborhood Hits	206	Shared Neighborhood Hits	11
SwissProt Accessions	P35689, Q61528, Q64248	Gene names	Ercc5, Ercc-5, Xpg
Domain Architecture
Description	DNA-repair protein complementing XP-G cells homolog (Xeroderma pigmentosum group G-complementing protein homolog) (DNA excision repair protein ERCC-5).

BCL9_HUMAN
NC score	0.032502 (rank : 90)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	142	Target Neighborhood Hits	1008	Shared Neighborhood Hits	45
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CD248_HUMAN
NC score	0.031794 (rank : 91)	θ value	0.21417 (rank : 35)
Query Neighborhood Hits	142	Target Neighborhood Hits	679	Shared Neighborhood Hits	28
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

SC24C_HUMAN
NC score	0.031476 (rank : 92)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	142	Target Neighborhood Hits	662	Shared Neighborhood Hits	30
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

BAG3_MOUSE
NC score	0.030973 (rank : 93)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	142	Target Neighborhood Hits	513	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

MINT_MOUSE
NC score	0.029728 (rank : 94)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	142	Target Neighborhood Hits	1514	Shared Neighborhood Hits	56
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MFAP1_MOUSE
NC score	0.029688 (rank : 95)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	142	Target Neighborhood Hits	353	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

SRRM2_HUMAN
NC score	0.029002 (rank : 96)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	142	Target Neighborhood Hits	1296	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

MDC1_MOUSE
NC score	0.027328 (rank : 97)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	142	Target Neighborhood Hits	998	Shared Neighborhood Hits	48
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

TSH3_MOUSE
NC score	0.026822 (rank : 98)	θ value	0.125558 (rank : 31)
Query Neighborhood Hits	142	Target Neighborhood Hits	590	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CGV9, Q5DTX4	Gene names	Tshz3, Kiaa1474, Tsh3, Zfp537, Znf537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

PI5PA_MOUSE
NC score	0.026685 (rank : 99)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	142	Target Neighborhood Hits	331	Shared Neighborhood Hits	31
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

FOG1_MOUSE
NC score	0.026538 (rank : 100)	θ value	0.00298849 (rank : 23)
Query Neighborhood Hits	142	Target Neighborhood Hits	1237	Shared Neighborhood Hits	45
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

B4GT1_HUMAN
NC score	0.026154 (rank : 101)	θ value	0.0736092 (rank : 26)
Query Neighborhood Hits	142	Target Neighborhood Hits	168	Shared Neighborhood Hits	3
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

NFAC1_HUMAN
NC score	0.025484 (rank : 102)	θ value	0.62314 (rank : 42)
Query Neighborhood Hits	142	Target Neighborhood Hits	312	Shared Neighborhood Hits	25
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

SMOO_HUMAN
NC score	0.025143 (rank : 103)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	142	Target Neighborhood Hits	391	Shared Neighborhood Hits	34
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

ETV6_HUMAN
NC score	0.025014 (rank : 104)	θ value	0.279714 (rank : 36)
Query Neighborhood Hits	142	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	P41212, Q9UMF6	Gene names	ETV6, TEL, TEL1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

PCLO_MOUSE
NC score	0.024870 (rank : 105)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	142	Target Neighborhood Hits	2275	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SEPT9_HUMAN
NC score	0.024503 (rank : 106)	θ value	0.813845 (rank : 47)
Query Neighborhood Hits	142	Target Neighborhood Hits	706	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

ARI1A_HUMAN
NC score	0.023526 (rank : 107)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	142	Target Neighborhood Hits	787	Shared Neighborhood Hits	39
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

CUTL1_MOUSE
NC score	0.023492 (rank : 108)	θ value	0.0252991 (rank : 25)
Query Neighborhood Hits	142	Target Neighborhood Hits	1620	Shared Neighborhood Hits	41
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

PER3_HUMAN
NC score	0.023353 (rank : 109)	θ value	2.36792 (rank : 74)
Query Neighborhood Hits	142	Target Neighborhood Hits	479	Shared Neighborhood Hits	30
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

CC28B_MOUSE
NC score	0.023291 (rank : 110)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	142	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CEG5, Q8K132	Gene names	Ccdc28b
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 28B.

IWS1_HUMAN
NC score	0.023229 (rank : 111)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	142	Target Neighborhood Hits	1241	Shared Neighborhood Hits	41
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CSKI1_MOUSE
NC score	0.022954 (rank : 112)	θ value	0.163984 (rank : 32)
Query Neighborhood Hits	142	Target Neighborhood Hits	1031	Shared Neighborhood Hits	46
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

OSBL2_HUMAN
NC score	0.022951 (rank : 113)	θ value	0.125558 (rank : 30)
Query Neighborhood Hits	142	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H1P3, Q9BZB1, Q9Y4B8	Gene names	OSBPL2, KIAA0772, ORP2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

CC28B_HUMAN
NC score	0.022895 (rank : 114)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	142	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BUN5, Q8TBV8	Gene names	CCDC28B
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 28B.

P66A_MOUSE
NC score	0.022293 (rank : 115)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	142	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CHY6, Q8BTQ2, Q8VEC9	Gene names	Gatad2a
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 alpha (GATA zinc finger domain- containing protein 2A).

CF010_HUMAN
NC score	0.021378 (rank : 116)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	142	Target Neighborhood Hits	329	Shared Neighborhood Hits	9
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

BAZ2A_MOUSE
NC score	0.021124 (rank : 117)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	142	Target Neighborhood Hits	744	Shared Neighborhood Hits	34
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

MFAP1_HUMAN
NC score	0.020369 (rank : 118)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	142	Target Neighborhood Hits	321	Shared Neighborhood Hits	11
SwissProt Accessions	P55081	Gene names	MFAP1
Domain Architecture
Description	Microfibrillar-associated protein 1.

CD248_MOUSE
NC score	0.019676 (rank : 119)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	142	Target Neighborhood Hits	578	Shared Neighborhood Hits	22
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

MAP1A_HUMAN
NC score	0.019099 (rank : 120)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	142	Target Neighborhood Hits	1626	Shared Neighborhood Hits	57
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

NALDL_MOUSE
NC score	0.018471 (rank : 121)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	142	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q7M758	Gene names	Naaladl1, Naaladasel
Domain Architecture	No domain graphic available
Description	N-acetylated-alpha-linked acidic dipeptidase-like protein (EC 3.4.17.21) (NAALADase L).

LRCH2_MOUSE
NC score	0.018317 (rank : 122)	θ value	0.163984 (rank : 33)
Query Neighborhood Hits	142	Target Neighborhood Hits	287	Shared Neighborhood Hits	5
SwissProt Accessions	Q3UMG5, Q7TNP9, Q80TC9	Gene names	Lrch2, Kiaa1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

SIX4_MOUSE
NC score	0.018071 (rank : 123)	θ value	0.62314 (rank : 43)
Query Neighborhood Hits	142	Target Neighborhood Hits	341	Shared Neighborhood Hits	6
SwissProt Accessions	Q61321, Q61322, Q61323	Gene names	Six4, Arec3
Domain Architecture
Description	Homeobox protein SIX4 (Sine oculis homeobox homolog 4) (Skeletal muscle-specific ARE-binding protein AREC3).

CTND2_HUMAN
NC score	0.017977 (rank : 124)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	142	Target Neighborhood Hits	333	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

MTSS1_HUMAN
NC score	0.017868 (rank : 125)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	142	Target Neighborhood Hits	504	Shared Neighborhood Hits	22
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

ENPL_HUMAN
NC score	0.017613 (rank : 126)	θ value	1.06291 (rank : 49)
Query Neighborhood Hits	142	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	P14625, Q96A97	Gene names	HSP90B1, TRA1
Domain Architecture
Description	Endoplasmin precursor (Heat shock protein 90 kDa beta member 1) (94 kDa glucose-regulated protein) (GRP94) (gp96 homolog) (Tumor rejection antigen 1).

AL2S8_MOUSE
NC score	0.017551 (rank : 127)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	142	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VHI4	Gene names	Als2cr8, Carf
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein homolog (Calcium-response factor) (CaRF).

NF2L1_HUMAN
NC score	0.016998 (rank : 128)	θ value	1.38821 (rank : 57)
Query Neighborhood Hits	142	Target Neighborhood Hits	169	Shared Neighborhood Hits	5
SwissProt Accessions	Q14494, Q12877, Q96FN6	Gene names	NFE2L1, HBZ17, NRF1, TCF11
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1) (Transcription factor 11) (Transcription factor HBZ17) (Transcription factor LCR-F1) (Locus control region-factor 1).

NPAS4_MOUSE
NC score	0.016984 (rank : 129)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	142	Target Neighborhood Hits	245	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

RT28_HUMAN
NC score	0.016944 (rank : 130)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	142	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2Q9, Q96Q21	Gene names	MRPS28, MRPS35
Domain Architecture	No domain graphic available
Description	Mitochondrial 28S ribosomal protein S28 (S28mt) (MRP-S28) (MRP-S35).

DMRTD_HUMAN
NC score	0.016512 (rank : 131)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	142	Target Neighborhood Hits	216	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

CEBPE_HUMAN
NC score	0.016027 (rank : 132)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	142	Target Neighborhood Hits	236	Shared Neighborhood Hits	5
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

TS13_MOUSE
NC score	0.015809 (rank : 133)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	142	Target Neighborhood Hits	191	Shared Neighborhood Hits	13
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

FRS3_MOUSE
NC score	0.015806 (rank : 134)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	142	Target Neighborhood Hits	168	Shared Neighborhood Hits	12
SwissProt Accessions	Q91WJ0	Gene names	Frs3, Frs2b
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FRS2-beta).

NADE1_MOUSE
NC score	0.014727 (rank : 135)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	142	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q711T7, Q711P6, Q8CFY6, Q9D280	Gene names	Nadsyn1
Domain Architecture	No domain graphic available
Description	Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]) (NAD(+) synthetase 1) (NH3-dependent NAD(+) synthetase-like protein).

RC3H1_HUMAN
NC score	0.014310 (rank : 136)	θ value	2.36792 (rank : 75)
Query Neighborhood Hits	142	Target Neighborhood Hits	433	Shared Neighborhood Hits	11
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

CUTL1_HUMAN
NC score	0.014203 (rank : 137)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	142	Target Neighborhood Hits	1574	Shared Neighborhood Hits	36
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

ZC3H6_HUMAN
NC score	0.014104 (rank : 138)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	142	Target Neighborhood Hits	228	Shared Neighborhood Hits	18
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

DOK3_MOUSE
NC score	0.013568 (rank : 139)	θ value	5.27518 (rank : 95)
Query Neighborhood Hits	142	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZK7	Gene names	Dok3, Dokl
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3) (P62(dok)-like protein) (DOK-L).

LPP_HUMAN
NC score	0.012934 (rank : 140)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	142	Target Neighborhood Hits	775	Shared Neighborhood Hits	31
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

ARI4A_HUMAN
NC score	0.012693 (rank : 141)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	142	Target Neighborhood Hits	434	Shared Neighborhood Hits	12
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

HAP1_HUMAN
NC score	0.012402 (rank : 142)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	142	Target Neighborhood Hits	606	Shared Neighborhood Hits	15
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

HDGR3_HUMAN
NC score	0.012296 (rank : 143)	θ value	5.27518 (rank : 96)
Query Neighborhood Hits	142	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y3E1	Gene names	HDGFRP3, HDGF2
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3) (Hepatoma- derived growth factor 2).

SYF2_MOUSE
NC score	0.012199 (rank : 144)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	142	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D198	Gene names	Syf2, Cbpin, Gcipip
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor SYF2 (CCNDBP1-interactor) (p29) (mp29).

FOXM1_HUMAN
NC score	0.011562 (rank : 145)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	142	Target Neighborhood Hits	167	Shared Neighborhood Hits	14
SwissProt Accessions	Q08050, O43258, O43259, O43260, Q4ZGG7, Q9BRL2	Gene names	FOXM1, FKHL16, HFH11, MPP2, WIN
Domain Architecture
Description	Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/fork-head homolog 11) (HFH-11) (Winged helix factor from INS-1 cells) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident).

S3TC2_MOUSE
NC score	0.011555 (rank : 146)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	142	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	Q80VA5, Q8BWH2, Q8BXB8, Q8C0G6	Gene names	Sh3tc2, Kiaa1985
Domain Architecture
Description	SH3 domain and tetratricopeptide repeats-containing protein 2.

LZTS1_MOUSE
NC score	0.011540 (rank : 147)	θ value	5.27518 (rank : 97)
Query Neighborhood Hits	142	Target Neighborhood Hits	540	Shared Neighborhood Hits	13
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

GLU2B_HUMAN
NC score	0.011470 (rank : 148)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	142	Target Neighborhood Hits	377	Shared Neighborhood Hits	10
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

INOC1_MOUSE
NC score	0.010898 (rank : 149)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	142	Target Neighborhood Hits	178	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

INOC1_HUMAN
NC score	0.010801 (rank : 150)	θ value	4.03905 (rank : 89)
Query Neighborhood Hits	142	Target Neighborhood Hits	181	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

TACC2_MOUSE
NC score	0.010673 (rank : 151)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	142	Target Neighborhood Hits	774	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

FGD3_HUMAN
NC score	0.010288 (rank : 152)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	142	Target Neighborhood Hits	249	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

LRCH2_HUMAN
NC score	0.009987 (rank : 153)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	142	Target Neighborhood Hits	315	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VUJ6, Q9HA88, Q9P233	Gene names	LRCH2, KIAA1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

SGOL2_MOUSE
NC score	0.009858 (rank : 154)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	142	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TSY8, Q811I4, Q8C9C4, Q8CGJ4, Q9CS55	Gene names	Sgol2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2.

BRDT_MOUSE
NC score	0.009394 (rank : 155)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	142	Target Neighborhood Hits	243	Shared Neighborhood Hits	14
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

NKTR_HUMAN
NC score	0.009390 (rank : 156)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	142	Target Neighborhood Hits	658	Shared Neighborhood Hits	21
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

BCN1_HUMAN
NC score	0.009276 (rank : 157)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	142	Target Neighborhood Hits	395	Shared Neighborhood Hits	8
SwissProt Accessions	Q14457, O75595, Q9UNA8	Gene names	BECN1, GT197
Domain Architecture
Description	Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197).

GNAS1_HUMAN
NC score	0.008930 (rank : 158)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	142	Target Neighborhood Hits	278	Shared Neighborhood Hits	21
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

BPAEA_HUMAN
NC score	0.008850 (rank : 159)	θ value	1.38821 (rank : 55)
Query Neighborhood Hits	142	Target Neighborhood Hits	1369	Shared Neighborhood Hits	20
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

MEF2D_HUMAN
NC score	0.008740 (rank : 160)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	142	Target Neighborhood Hits	170	Shared Neighborhood Hits	13
SwissProt Accessions	Q14814, Q14815	Gene names	MEF2D
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

DLGP1_HUMAN
NC score	0.008034 (rank : 161)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	142	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	O14490, O14489, P78335	Gene names	DLGAP1, DAP1, GKAP
Domain Architecture
Description	Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (hGKAP) (SAP90/PSD-95-associated protein 1) (SAPAP1) (PSD- 95/SAP90-binding protein 1).

DDX51_HUMAN
NC score	0.008022 (rank : 162)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	142	Target Neighborhood Hits	332	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

CAC1B_MOUSE
NC score	0.008006 (rank : 163)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	142	Target Neighborhood Hits	351	Shared Neighborhood Hits	20
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

YTHD2_HUMAN
NC score	0.007698 (rank : 164)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	142	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y5A9, Q5VSZ9, Q8TDH0, Q9BUJ5	Gene names	YTHDF2, HGRG8
Domain Architecture
Description	YTH domain family protein 2 (High-glucose-regulated protein 8) (NY- REN-2 antigen) (CLL-associated antigen KW-14).

PRKDC_HUMAN
NC score	0.007673 (rank : 165)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	142	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3	Gene names	PRKDC
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460).

SFRS4_HUMAN
NC score	0.007389 (rank : 166)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	142	Target Neighborhood Hits	384	Shared Neighborhood Hits	12
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

BPA1_MOUSE
NC score	0.006821 (rank : 167)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	142	Target Neighborhood Hits	1477	Shared Neighborhood Hits	24
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

RNPL1_HUMAN
NC score	0.006540 (rank : 168)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	142	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HAU8, Q96AC9, Q9H033, Q9NVD0	Gene names	RNPEPL1
Domain Architecture
Description	Arginyl aminopeptidase-like 1 (EC 3.4.11.-) (RNPEP-like protein).

SM1L2_HUMAN
NC score	0.006496 (rank : 169)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	142	Target Neighborhood Hits	1019	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

MUG2_MOUSE
NC score	0.006239 (rank : 170)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	142	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	P28666	Gene names	Mug2, Mug-2
Domain Architecture
Description	Murinoglobulin-2 precursor (MuG2).

RBY1A_HUMAN
NC score	0.005544 (rank : 171)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	142	Target Neighborhood Hits	245	Shared Neighborhood Hits	4
SwissProt Accessions	Q15414, Q15377, Q8NHR0	Gene names	RBMY1A1, RBM1, YRRM1
Domain Architecture
Description	RNA-binding motif protein, Y chromosome, family 1 member A1 (RNA- binding motif protein 1).

ZBT17_MOUSE
NC score	0.005203 (rank : 172)	θ value	0.0961366 (rank : 29)
Query Neighborhood Hits	142	Target Neighborhood Hits	940	Shared Neighborhood Hits	18
SwissProt Accessions	Q60821, Q60699	Gene names	Zbtb17, Zfp100, Znf151
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 17 (Zinc finger protein 151) (Zinc finger protein 100) (Zfp-100) (Polyomavirus late initiator promoter-binding protein) (LP-1) (Zinc finger protein Z13).

MCP_MOUSE
NC score	0.004787 (rank : 173)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	142	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	O88174, Q9R0R9	Gene names	Cd46, Mcp
Domain Architecture	No domain graphic available
Description	Membrane cofactor protein precursor (CD46 antigen).

PARD3_HUMAN
NC score	0.004321 (rank : 174)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	142	Target Neighborhood Hits	312	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

ZBT17_HUMAN
NC score	0.004318 (rank : 175)	θ value	0.813845 (rank : 48)
Query Neighborhood Hits	142	Target Neighborhood Hits	925	Shared Neighborhood Hits	14
SwissProt Accessions	Q13105, Q15932, Q5JYB2, Q9NUC9	Gene names	ZBTB17, MIZ1, ZNF151
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 17 (Zinc finger protein 151) (Myc-interacting zinc finger protein) (Miz-1 protein).

FOXC2_MOUSE
NC score	0.004000 (rank : 176)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	142	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	Q61850, P97948, Q63869, Q8C694	Gene names	Foxc2, Fkh14, Fkhl14, Mfh1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

BCL6_HUMAN
NC score	0.003920 (rank : 177)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	142	Target Neighborhood Hits	922	Shared Neighborhood Hits	21
SwissProt Accessions	P41182	Gene names	BCL6, BCL5, LAZ3, ZBTB27, ZNF51
Domain Architecture
Description	B-cell lymphoma 6 protein (BCL-6) (Zinc finger protein 51) (LAZ-3 protein) (BCL-5) (Zinc finger and BTB domain-containing protein 27).

ZN688_HUMAN
NC score	0.003738 (rank : 178)	θ value	1.81305 (rank : 69)
Query Neighborhood Hits	142	Target Neighborhood Hits	873	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WV14, O75701, Q8IW91, Q96MN0	Gene names	ZNF688
Domain Architecture	No domain graphic available
Description	Zinc finger protein 688.

ZN509_MOUSE
NC score	0.003700 (rank : 179)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	142	Target Neighborhood Hits	990	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

ZN667_HUMAN
NC score	0.002917 (rank : 180)	θ value	0.47712 (rank : 39)
Query Neighborhood Hits	142	Target Neighborhood Hits	773	Shared Neighborhood Hits	12
SwissProt Accessions	Q5HYK9, Q6B093, Q9H807	Gene names	ZNF667
Domain Architecture	No domain graphic available
Description	Zinc finger protein 667.

PCDA5_HUMAN
NC score	0.002000 (rank : 181)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	142	Target Neighborhood Hits	217	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y5H7, O75284, Q8N4R3	Gene names	PCDHA5
Domain Architecture
Description	Protocadherin alpha 5 precursor (PCDH-alpha5).

ZN621_HUMAN
NC score	0.001567 (rank : 182)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	142	Target Neighborhood Hits	737	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZSS3, Q8TE91	Gene names	ZNF621
Domain Architecture	No domain graphic available
Description	Zinc finger protein 621.

MK15_HUMAN
NC score	-0.001318 (rank : 183)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	142	Target Neighborhood Hits	1038	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

KPCL_HUMAN
NC score	-0.002588 (rank : 184)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	142	Target Neighborhood Hits	887	Shared Neighborhood Hits	3
SwissProt Accessions	P24723, Q16246	Gene names	PRKCH, PKCL
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).