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Network neighborhood for query Sequence : PSD4_HUMAN

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PSD4_HUMAN
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PSD4_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	178	Target Neighborhood Hits	178	Shared Neighborhood Hits	178
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

PSD4_MOUSE
θ value	0 (rank : 2)	NC score	0.970280 (rank : 2)
Query Neighborhood Hits	178	Target Neighborhood Hits	78	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44	Gene names	Psd4
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).

PSD3_HUMAN
θ value	1.69605e-115 (rank : 3)	NC score	0.938976 (rank : 3)
Query Neighborhood Hits	178	Target Neighborhood Hits	75	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NYI0, Q9Y2F1	Gene names	PSD3, EFA6R, HCA67, KIAA0942
Domain Architecture
Description	PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).

CYH3_MOUSE
θ value	7.30988e-26 (rank : 4)	NC score	0.716163 (rank : 8)
Query Neighborhood Hits	178	Target Neighborhood Hits	148	Shared Neighborhood Hits	36
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

CYH1_MOUSE
θ value	3.62785e-25 (rank : 5)	NC score	0.717936 (rank : 7)
Query Neighborhood Hits	178	Target Neighborhood Hits	176	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH3_HUMAN
θ value	8.08199e-25 (rank : 6)	NC score	0.719671 (rank : 6)
Query Neighborhood Hits	178	Target Neighborhood Hits	137	Shared Neighborhood Hits	35
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH1_HUMAN
θ value	2.35151e-24 (rank : 7)	NC score	0.714782 (rank : 9)
Query Neighborhood Hits	178	Target Neighborhood Hits	184	Shared Neighborhood Hits	35
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH2_HUMAN
θ value	2.35151e-24 (rank : 8)	NC score	0.720829 (rank : 4)
Query Neighborhood Hits	178	Target Neighborhood Hits	175	Shared Neighborhood Hits	34
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
θ value	1.16704e-23 (rank : 9)	NC score	0.719762 (rank : 5)
Query Neighborhood Hits	178	Target Neighborhood Hits	171	Shared Neighborhood Hits	34
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH4_MOUSE
θ value	3.17815e-21 (rank : 10)	NC score	0.714060 (rank : 11)
Query Neighborhood Hits	178	Target Neighborhood Hits	134	Shared Neighborhood Hits	35
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

CYH4_HUMAN
θ value	4.15078e-21 (rank : 11)	NC score	0.713559 (rank : 12)
Query Neighborhood Hits	178	Target Neighborhood Hits	135	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

BIG1_HUMAN
θ value	7.82807e-20 (rank : 12)	NC score	0.699196 (rank : 14)
Query Neighborhood Hits	178	Target Neighborhood Hits	76	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

IQEC1_HUMAN
θ value	6.62687e-19 (rank : 13)	NC score	0.691223 (rank : 17)
Query Neighborhood Hits	178	Target Neighborhood Hits	76	Shared Neighborhood Hits	25
SwissProt Accessions	Q6DN90, O94863, Q96D85	Gene names	IQSEC1, ARFGEP100, BRAG2, KIAA0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein).

IQEC1_MOUSE
θ value	1.92812e-18 (rank : 14)	NC score	0.691505 (rank : 16)
Query Neighborhood Hits	178	Target Neighborhood Hits	54	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R0S2, Q3TZC3, Q5DU15	Gene names	Iqsec1, Kiaa0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1.

BIG2_HUMAN
θ value	1.63225e-17 (rank : 15)	NC score	0.687635 (rank : 18)
Query Neighborhood Hits	178	Target Neighborhood Hits	66	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

IQEC3_HUMAN
θ value	1.63225e-17 (rank : 16)	NC score	0.700195 (rank : 13)
Query Neighborhood Hits	178	Target Neighborhood Hits	125	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IQEC3_MOUSE
θ value	1.63225e-17 (rank : 17)	NC score	0.696952 (rank : 15)
Query Neighborhood Hits	178	Target Neighborhood Hits	274	Shared Neighborhood Hits	46
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

GBF1_HUMAN
θ value	3.63628e-17 (rank : 18)	NC score	0.714305 (rank : 10)
Query Neighborhood Hits	178	Target Neighborhood Hits	142	Shared Neighborhood Hits	36
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

IQEC2_MOUSE
θ value	3.07829e-16 (rank : 19)	NC score	0.658556 (rank : 19)
Query Neighborhood Hits	178	Target Neighborhood Hits	417	Shared Neighborhood Hits	51
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_HUMAN
θ value	6.85773e-16 (rank : 20)	NC score	0.656997 (rank : 20)
Query Neighborhood Hits	178	Target Neighborhood Hits	403	Shared Neighborhood Hits	50
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

SPTN2_HUMAN
θ value	1.33837e-11 (rank : 21)	NC score	0.155490 (rank : 28)
Query Neighborhood Hits	178	Target Neighborhood Hits	535	Shared Neighborhood Hits	30
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

SPTB2_MOUSE
θ value	2.13673e-09 (rank : 22)	NC score	0.132099 (rank : 35)
Query Neighborhood Hits	178	Target Neighborhood Hits	770	Shared Neighborhood Hits	35
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTB2_HUMAN
θ value	3.64472e-09 (rank : 23)	NC score	0.131100 (rank : 36)
Query Neighborhood Hits	178	Target Neighborhood Hits	748	Shared Neighborhood Hits	33
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTN4_HUMAN
θ value	3.41135e-07 (rank : 24)	NC score	0.141939 (rank : 31)
Query Neighborhood Hits	178	Target Neighborhood Hits	570	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

FBX8_HUMAN
θ value	9.92553e-07 (rank : 25)	NC score	0.612871 (rank : 22)
Query Neighborhood Hits	178	Target Neighborhood Hits	44	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NRD0, Q6UWN4, Q9NRP5, Q9UKC4	Gene names	FBXO8, FBS, FBX8
Domain Architecture
Description	F-box only protein 8 (F-box/SEC7 protein FBS).

FBX8_MOUSE
θ value	9.92553e-07 (rank : 26)	NC score	0.614194 (rank : 21)
Query Neighborhood Hits	178	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QZN3	Gene names	Fbxo8, Fbx8
Domain Architecture
Description	F-box only protein 8.

NFH_MOUSE
θ value	7.1131e-05 (rank : 27)	NC score	0.054067 (rank : 93)
Query Neighborhood Hits	178	Target Neighborhood Hits	2247	Shared Neighborhood Hits	99
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CNKR1_HUMAN
θ value	0.000270298 (rank : 28)	NC score	0.266161 (rank : 23)
Query Neighborhood Hits	178	Target Neighborhood Hits	154	Shared Neighborhood Hits	34
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

MYLK_MOUSE
θ value	0.00102713 (rank : 29)	NC score	0.016693 (rank : 184)
Query Neighborhood Hits	178	Target Neighborhood Hits	1489	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

TIAM1_HUMAN
θ value	0.00102713 (rank : 30)	NC score	0.124864 (rank : 38)
Query Neighborhood Hits	178	Target Neighborhood Hits	225	Shared Neighborhood Hits	23
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TIAM1_MOUSE
θ value	0.00390308 (rank : 31)	NC score	0.118891 (rank : 41)
Query Neighborhood Hits	178	Target Neighborhood Hits	205	Shared Neighborhood Hits	20
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

MAST4_HUMAN
θ value	0.0148317 (rank : 32)	NC score	0.018747 (rank : 179)
Query Neighborhood Hits	178	Target Neighborhood Hits	1804	Shared Neighborhood Hits	68
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MAGE1_HUMAN
θ value	0.0193708 (rank : 33)	NC score	0.046686 (rank : 109)
Query Neighborhood Hits	178	Target Neighborhood Hits	1389	Shared Neighborhood Hits	82
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MUC1_HUMAN
θ value	0.0252991 (rank : 34)	NC score	0.048399 (rank : 103)
Query Neighborhood Hits	178	Target Neighborhood Hits	975	Shared Neighborhood Hits	59
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MLL2_HUMAN
θ value	0.0330416 (rank : 35)	NC score	0.053016 (rank : 97)
Query Neighborhood Hits	178	Target Neighborhood Hits	1788	Shared Neighborhood Hits	74
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MY18B_HUMAN
θ value	0.0330416 (rank : 36)	NC score	0.027691 (rank : 141)
Query Neighborhood Hits	178	Target Neighborhood Hits	1299	Shared Neighborhood Hits	51
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

GLDN_MOUSE
θ value	0.0563607 (rank : 37)	NC score	0.025006 (rank : 148)
Query Neighborhood Hits	178	Target Neighborhood Hits	155	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BMF8, Q80ZC5	Gene names	Gldn, Crgl2
Domain Architecture	No domain graphic available
Description	Gliomedin (Cancer-related gene liver 2 protein) (CRG-L2).

SET1A_HUMAN
θ value	0.0563607 (rank : 38)	NC score	0.063413 (rank : 65)
Query Neighborhood Hits	178	Target Neighborhood Hits	690	Shared Neighborhood Hits	50
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

K1849_MOUSE
θ value	0.0736092 (rank : 39)	NC score	0.029670 (rank : 137)
Query Neighborhood Hits	178	Target Neighborhood Hits	335	Shared Neighborhood Hits	15
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

SCUB3_MOUSE
θ value	0.0736092 (rank : 40)	NC score	0.020303 (rank : 170)
Query Neighborhood Hits	178	Target Neighborhood Hits	442	Shared Neighborhood Hits	6
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

PKHA6_HUMAN
θ value	0.0961366 (rank : 41)	NC score	0.207145 (rank : 24)
Query Neighborhood Hits	178	Target Neighborhood Hits	556	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PLEK_MOUSE
θ value	0.0961366 (rank : 42)	NC score	0.181883 (rank : 27)
Query Neighborhood Hits	178	Target Neighborhood Hits	109	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

SCUB3_HUMAN
θ value	0.0961366 (rank : 43)	NC score	0.020097 (rank : 172)
Query Neighborhood Hits	178	Target Neighborhood Hits	428	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

MYLK_HUMAN
θ value	0.125558 (rank : 44)	NC score	0.012291 (rank : 200)
Query Neighborhood Hits	178	Target Neighborhood Hits	1328	Shared Neighborhood Hits	19
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

PKHA5_HUMAN
θ value	0.125558 (rank : 45)	NC score	0.147481 (rank : 29)
Query Neighborhood Hits	178	Target Neighborhood Hits	455	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

CSF1_HUMAN
θ value	0.163984 (rank : 46)	NC score	0.048080 (rank : 104)
Query Neighborhood Hits	178	Target Neighborhood Hits	258	Shared Neighborhood Hits	24
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

OGFR_HUMAN
θ value	0.163984 (rank : 47)	NC score	0.061017 (rank : 69)
Query Neighborhood Hits	178	Target Neighborhood Hits	1582	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

RGS3_MOUSE
θ value	0.21417 (rank : 48)	NC score	0.054233 (rank : 92)
Query Neighborhood Hits	178	Target Neighborhood Hits	1621	Shared Neighborhood Hits	92
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CN155_HUMAN
θ value	0.279714 (rank : 49)	NC score	0.086595 (rank : 52)
Query Neighborhood Hits	178	Target Neighborhood Hits	385	Shared Neighborhood Hits	36
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

DMN_HUMAN
θ value	0.365318 (rank : 50)	NC score	0.019573 (rank : 176)
Query Neighborhood Hits	178	Target Neighborhood Hits	690	Shared Neighborhood Hits	18
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

EAN57_HUMAN
θ value	0.365318 (rank : 51)	NC score	0.042606 (rank : 115)
Query Neighborhood Hits	178	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	O43247, Q6ICF2, Q9Y4V8	Gene names	EAN57
Domain Architecture	No domain graphic available
Description	Protein EAN57.

OBSCN_HUMAN
θ value	0.365318 (rank : 52)	NC score	0.014825 (rank : 193)
Query Neighborhood Hits	178	Target Neighborhood Hits	1931	Shared Neighborhood Hits	61
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PKHA6_MOUSE
θ value	0.365318 (rank : 53)	NC score	0.201690 (rank : 25)
Query Neighborhood Hits	178	Target Neighborhood Hits	591	Shared Neighborhood Hits	53
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

LRIG1_HUMAN
θ value	0.47712 (rank : 54)	NC score	0.010214 (rank : 206)
Query Neighborhood Hits	178	Target Neighborhood Hits	654	Shared Neighborhood Hits	10
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

PLEK_HUMAN
θ value	0.47712 (rank : 55)	NC score	0.185205 (rank : 26)
Query Neighborhood Hits	178	Target Neighborhood Hits	110	Shared Neighborhood Hits	25
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

NCA11_MOUSE
θ value	0.62314 (rank : 56)	NC score	0.026086 (rank : 143)
Query Neighborhood Hits	178	Target Neighborhood Hits	661	Shared Neighborhood Hits	35
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

PCDH9_HUMAN
θ value	0.62314 (rank : 57)	NC score	0.004184 (rank : 227)
Query Neighborhood Hits	178	Target Neighborhood Hits	180	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HC56	Gene names	PCDH9
Domain Architecture
Description	Protocadherin-9 precursor.

PI5PA_HUMAN
θ value	0.62314 (rank : 58)	NC score	0.040365 (rank : 118)
Query Neighborhood Hits	178	Target Neighborhood Hits	749	Shared Neighborhood Hits	57
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

SON_HUMAN
θ value	0.62314 (rank : 59)	NC score	0.041493 (rank : 117)
Query Neighborhood Hits	178	Target Neighborhood Hits	1568	Shared Neighborhood Hits	88
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TARA_MOUSE
θ value	0.62314 (rank : 60)	NC score	0.068546 (rank : 63)
Query Neighborhood Hits	178	Target Neighborhood Hits	1133	Shared Neighborhood Hits	63
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

APXL_HUMAN
θ value	0.813845 (rank : 61)	NC score	0.043084 (rank : 113)
Query Neighborhood Hits	178	Target Neighborhood Hits	553	Shared Neighborhood Hits	37
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

CSPG5_MOUSE
θ value	0.813845 (rank : 62)	NC score	0.038757 (rank : 119)
Query Neighborhood Hits	178	Target Neighborhood Hits	211	Shared Neighborhood Hits	17
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

OSB10_HUMAN
θ value	0.813845 (rank : 63)	NC score	0.030378 (rank : 136)
Query Neighborhood Hits	178	Target Neighborhood Hits	55	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BXB5, Q9BTU5	Gene names	OSBPL10, ORP10, OSBP9
Domain Architecture
Description	Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).

PHAR2_HUMAN
θ value	0.813845 (rank : 64)	NC score	0.044099 (rank : 111)
Query Neighborhood Hits	178	Target Neighborhood Hits	208	Shared Neighborhood Hits	21
SwissProt Accessions	O75167, Q68DM2	Gene names	PHACTR2, C6orf56, KIAA0680
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 2.

BAT3_MOUSE
θ value	1.06291 (rank : 65)	NC score	0.047084 (rank : 108)
Query Neighborhood Hits	178	Target Neighborhood Hits	518	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

FGD6_HUMAN
θ value	1.06291 (rank : 66)	NC score	0.047744 (rank : 107)
Query Neighborhood Hits	178	Target Neighborhood Hits	237	Shared Neighborhood Hits	24
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

SPR2F_MOUSE
θ value	1.06291 (rank : 67)	NC score	0.041584 (rank : 116)
Query Neighborhood Hits	178	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

ZC3H6_MOUSE
θ value	1.06291 (rank : 68)	NC score	0.021006 (rank : 166)
Query Neighborhood Hits	178	Target Neighborhood Hits	239	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

BOC_HUMAN
θ value	1.38821 (rank : 69)	NC score	0.016316 (rank : 186)
Query Neighborhood Hits	178	Target Neighborhood Hits	543	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

HOOK2_HUMAN
θ value	1.38821 (rank : 70)	NC score	0.020296 (rank : 171)
Query Neighborhood Hits	178	Target Neighborhood Hits	714	Shared Neighborhood Hits	15
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

INVS_MOUSE
θ value	1.38821 (rank : 71)	NC score	0.011680 (rank : 203)
Query Neighborhood Hits	178	Target Neighborhood Hits	609	Shared Neighborhood Hits	39
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

PCNT_MOUSE
θ value	1.38821 (rank : 72)	NC score	0.021696 (rank : 161)
Query Neighborhood Hits	178	Target Neighborhood Hits	1207	Shared Neighborhood Hits	27
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

PDZD2_HUMAN
θ value	1.38821 (rank : 73)	NC score	0.028062 (rank : 140)
Query Neighborhood Hits	178	Target Neighborhood Hits	772	Shared Neighborhood Hits	49
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PRPC_HUMAN
θ value	1.38821 (rank : 74)	NC score	0.052229 (rank : 99)
Query Neighborhood Hits	178	Target Neighborhood Hits	165	Shared Neighborhood Hits	19
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

CAN10_MOUSE
θ value	1.81305 (rank : 75)	NC score	0.011738 (rank : 201)
Query Neighborhood Hits	178	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ESK3, Q99J13, Q9WVF0	Gene names	Capn10, Capn8
Domain Architecture
Description	Calpain-10 (EC 3.4.22.-) (Calcium-activated neutral proteinase 10) (CANP 10).

FBLN2_MOUSE
θ value	1.81305 (rank : 76)	NC score	0.012826 (rank : 197)
Query Neighborhood Hits	178	Target Neighborhood Hits	505	Shared Neighborhood Hits	28
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

K1688_HUMAN
θ value	1.81305 (rank : 77)	NC score	0.019954 (rank : 173)
Query Neighborhood Hits	178	Target Neighborhood Hits	217	Shared Neighborhood Hits	15
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

MILK1_MOUSE
θ value	1.81305 (rank : 78)	NC score	0.087679 (rank : 51)
Query Neighborhood Hits	178	Target Neighborhood Hits	788	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

SPR2I_MOUSE
θ value	1.81305 (rank : 79)	NC score	0.037147 (rank : 126)
Query Neighborhood Hits	178	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

TACC2_MOUSE
θ value	1.81305 (rank : 80)	NC score	0.024171 (rank : 154)
Query Neighborhood Hits	178	Target Neighborhood Hits	774	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TNFC_MOUSE
θ value	1.81305 (rank : 81)	NC score	0.025192 (rank : 146)
Query Neighborhood Hits	178	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P41155	Gene names	Ltb, Tnfc, Tnfsf3
Domain Architecture
Description	Lymphotoxin-beta (LT-beta) (Tumor necrosis factor C) (TNF-C) (Tumor necrosis factor ligand superfamily member 3).

AIM1_HUMAN
θ value	2.36792 (rank : 82)	NC score	0.037996 (rank : 123)
Query Neighborhood Hits	178	Target Neighborhood Hits	247	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

B3A2_MOUSE
θ value	2.36792 (rank : 83)	NC score	0.009767 (rank : 208)
Query Neighborhood Hits	178	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	P13808, Q9ES09, Q9ES10, Q9ES11, Q9ES12, Q9ES13	Gene names	Slc4a2, Ae2
Domain Architecture
Description	Anion exchange protein 2 (Non-erythroid band 3-like protein) (AE2 anion exchanger) (Solute carrier family 4 member 2) (B3RP).

BTBDA_MOUSE
θ value	2.36792 (rank : 84)	NC score	0.028328 (rank : 139)
Query Neighborhood Hits	178	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q80X66	Gene names	Btbd10
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 10.

CO027_HUMAN
θ value	2.36792 (rank : 85)	NC score	0.024409 (rank : 152)
Query Neighborhood Hits	178	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q2M3C6, Q8N993, Q96LL5	Gene names	C15orf27
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf27.

ETV6_HUMAN
θ value	2.36792 (rank : 86)	NC score	0.016048 (rank : 188)
Query Neighborhood Hits	178	Target Neighborhood Hits	120	Shared Neighborhood Hits	10
SwissProt Accessions	P41212, Q9UMF6	Gene names	ETV6, TEL, TEL1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

K1802_HUMAN
θ value	2.36792 (rank : 87)	NC score	0.038082 (rank : 122)
Query Neighborhood Hits	178	Target Neighborhood Hits	1378	Shared Neighborhood Hits	62
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LIGA_HUMAN
θ value	2.36792 (rank : 88)	NC score	0.021402 (rank : 163)
Query Neighborhood Hits	178	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	P41214, Q9NR27, Q9NSN0, Q9NV18, Q9NZ21	Gene names	LGTN, HCA56
Domain Architecture
Description	Ligatin (Hepatocellular carcinoma-associated antigen 56).

MILK1_HUMAN
θ value	2.36792 (rank : 89)	NC score	0.085167 (rank : 53)
Query Neighborhood Hits	178	Target Neighborhood Hits	427	Shared Neighborhood Hits	45
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

NBEA_MOUSE
θ value	2.36792 (rank : 90)	NC score	0.012917 (rank : 196)
Query Neighborhood Hits	178	Target Neighborhood Hits	225	Shared Neighborhood Hits	13
SwissProt Accessions	Q9EPN1, Q8C931, Q9EPM9, Q9EPN0, Q9WVM9	Gene names	Nbea, Lyst2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2).

PLRG1_MOUSE
θ value	2.36792 (rank : 91)	NC score	0.003892 (rank : 228)
Query Neighborhood Hits	178	Target Neighborhood Hits	308	Shared Neighborhood Hits	2
SwissProt Accessions	Q922V4, O55039	Gene names	Plrg1
Domain Architecture
Description	Pleiotropic regulator 1.

RGS3_HUMAN
θ value	2.36792 (rank : 92)	NC score	0.044083 (rank : 112)
Query Neighborhood Hits	178	Target Neighborhood Hits	1375	Shared Neighborhood Hits	82
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SHAN2_MOUSE
θ value	2.36792 (rank : 93)	NC score	0.023875 (rank : 156)
Query Neighborhood Hits	178	Target Neighborhood Hits	446	Shared Neighborhood Hits	32
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SOX17_MOUSE
θ value	2.36792 (rank : 94)	NC score	0.015073 (rank : 192)
Query Neighborhood Hits	178	Target Neighborhood Hits	223	Shared Neighborhood Hits	16
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

SPR2E_MOUSE
θ value	2.36792 (rank : 95)	NC score	0.032512 (rank : 134)
Query Neighborhood Hits	178	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

TIF1G_MOUSE
θ value	2.36792 (rank : 96)	NC score	0.025221 (rank : 145)
Query Neighborhood Hits	178	Target Neighborhood Hits	498	Shared Neighborhood Hits	34
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

ZCPW1_MOUSE
θ value	2.36792 (rank : 97)	NC score	0.025090 (rank : 147)
Query Neighborhood Hits	178	Target Neighborhood Hits	307	Shared Neighborhood Hits	19
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

AATK_HUMAN
θ value	3.0926 (rank : 98)	NC score	0.006778 (rank : 216)
Query Neighborhood Hits	178	Target Neighborhood Hits	1243	Shared Neighborhood Hits	47
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

AFF1_MOUSE
θ value	3.0926 (rank : 99)	NC score	0.035580 (rank : 129)
Query Neighborhood Hits	178	Target Neighborhood Hits	351	Shared Neighborhood Hits	33
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

CNOT3_MOUSE
θ value	3.0926 (rank : 100)	NC score	0.034278 (rank : 130)
Query Neighborhood Hits	178	Target Neighborhood Hits	504	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

COIA1_MOUSE
θ value	3.0926 (rank : 101)	NC score	0.021807 (rank : 160)
Query Neighborhood Hits	178	Target Neighborhood Hits	481	Shared Neighborhood Hits	33
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

DIDO1_HUMAN
θ value	3.0926 (rank : 102)	NC score	0.033623 (rank : 133)
Query Neighborhood Hits	178	Target Neighborhood Hits	960	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

FGD5_HUMAN
θ value	3.0926 (rank : 103)	NC score	0.037038 (rank : 127)
Query Neighborhood Hits	178	Target Neighborhood Hits	235	Shared Neighborhood Hits	23
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

MAP2_HUMAN
θ value	3.0926 (rank : 104)	NC score	0.023599 (rank : 157)
Query Neighborhood Hits	178	Target Neighborhood Hits	348	Shared Neighborhood Hits	23
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

NFAC1_MOUSE
θ value	3.0926 (rank : 105)	NC score	0.015249 (rank : 191)
Query Neighborhood Hits	178	Target Neighborhood Hits	92	Shared Neighborhood Hits	10
SwissProt Accessions	O88942, O70345	Gene names	Nfatc1, Nfat2, Nfatc
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

PP16A_HUMAN
θ value	3.0926 (rank : 106)	NC score	0.005320 (rank : 220)
Query Neighborhood Hits	178	Target Neighborhood Hits	340	Shared Neighborhood Hits	7
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

SYN3_HUMAN
θ value	3.0926 (rank : 107)	NC score	0.024602 (rank : 149)
Query Neighborhood Hits	178	Target Neighborhood Hits	203	Shared Neighborhood Hits	28
SwissProt Accessions	O14994	Gene names	SYN3
Domain Architecture
Description	Synapsin-3 (Synapsin III).

TXLNB_HUMAN
θ value	3.0926 (rank : 108)	NC score	0.024519 (rank : 150)
Query Neighborhood Hits	178	Target Neighborhood Hits	912	Shared Neighborhood Hits	53
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

USH2A_MOUSE
θ value	3.0926 (rank : 109)	NC score	0.006637 (rank : 218)
Query Neighborhood Hits	178	Target Neighborhood Hits	626	Shared Neighborhood Hits	15
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

WBS14_MOUSE
θ value	3.0926 (rank : 110)	NC score	0.027489 (rank : 142)
Query Neighborhood Hits	178	Target Neighborhood Hits	171	Shared Neighborhood Hits	17
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

ZN142_HUMAN
θ value	3.0926 (rank : 111)	NC score	0.000113 (rank : 233)
Query Neighborhood Hits	178	Target Neighborhood Hits	1007	Shared Neighborhood Hits	29
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

AIRE_MOUSE
θ value	4.03905 (rank : 112)	NC score	0.019862 (rank : 174)
Query Neighborhood Hits	178	Target Neighborhood Hits	196	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

CAC1G_HUMAN
θ value	4.03905 (rank : 113)	NC score	0.025429 (rank : 144)
Query Neighborhood Hits	178	Target Neighborhood Hits	587	Shared Neighborhood Hits	44
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CBP_MOUSE
θ value	4.03905 (rank : 114)	NC score	0.035696 (rank : 128)
Query Neighborhood Hits	178	Target Neighborhood Hits	1051	Shared Neighborhood Hits	59
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DDEF1_MOUSE
θ value	4.03905 (rank : 115)	NC score	0.009681 (rank : 209)
Query Neighborhood Hits	178	Target Neighborhood Hits	592	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

JPH2_MOUSE
θ value	4.03905 (rank : 116)	NC score	0.020982 (rank : 167)
Query Neighborhood Hits	178	Target Neighborhood Hits	279	Shared Neighborhood Hits	24
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

K1949_HUMAN
θ value	4.03905 (rank : 117)	NC score	0.021670 (rank : 162)
Query Neighborhood Hits	178	Target Neighborhood Hits	121	Shared Neighborhood Hits	12
SwissProt Accessions	Q6NYC8, Q68CK8, Q6ZUJ6, Q8NDQ4, Q8TF52, Q9BRL9	Gene names	KIAA1949
Domain Architecture	No domain graphic available
Description	Protein KIAA1949.

KIF9_HUMAN
θ value	4.03905 (rank : 118)	NC score	0.004417 (rank : 226)
Query Neighborhood Hits	178	Target Neighborhood Hits	118	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HAQ2, Q86Z28, Q9H8A4	Gene names	KIF9
Domain Architecture
Description	Kinesin-like protein KIF9.

PCSK7_HUMAN
θ value	4.03905 (rank : 119)	NC score	0.007783 (rank : 214)
Query Neighborhood Hits	178	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q16549, Q9UL57	Gene names	PCSK7, LPC, PC7, PC8, SPC7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (PC8) (hPC8) (Lymphoma proprotein convertase).

PHC3_HUMAN
θ value	4.03905 (rank : 120)	NC score	0.020544 (rank : 168)
Query Neighborhood Hits	178	Target Neighborhood Hits	218	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

RERE_HUMAN
θ value	4.03905 (rank : 121)	NC score	0.037453 (rank : 125)
Query Neighborhood Hits	178	Target Neighborhood Hits	779	Shared Neighborhood Hits	51
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SPR2H_MOUSE
θ value	4.03905 (rank : 122)	NC score	0.023894 (rank : 155)
Query Neighborhood Hits	178	Target Neighborhood Hits	82	Shared Neighborhood Hits	7
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

SRRM2_HUMAN
θ value	4.03905 (rank : 123)	NC score	0.054389 (rank : 90)
Query Neighborhood Hits	178	Target Neighborhood Hits	1296	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TARA_HUMAN
θ value	4.03905 (rank : 124)	NC score	0.057876 (rank : 83)
Query Neighborhood Hits	178	Target Neighborhood Hits	1626	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

BTBDA_HUMAN
θ value	5.27518 (rank : 125)	NC score	0.024493 (rank : 151)
Query Neighborhood Hits	178	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BSF8, Q86WG1	Gene names	BTBD10
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 10.

CUTL2_MOUSE
θ value	5.27518 (rank : 126)	NC score	0.019236 (rank : 177)
Query Neighborhood Hits	178	Target Neighborhood Hits	771	Shared Neighborhood Hits	38
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

FRS3_HUMAN
θ value	5.27518 (rank : 127)	NC score	0.012400 (rank : 199)
Query Neighborhood Hits	178	Target Neighborhood Hits	76	Shared Neighborhood Hits	7
SwissProt Accessions	O43559, Q5T3D5	Gene names	FRS3
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (Suc1-associated neurotrophic factor target 2) (SNT-2) (FGFR signaling adaptor SNT2).

IF4G3_MOUSE
θ value	5.27518 (rank : 128)	NC score	0.017865 (rank : 180)
Query Neighborhood Hits	178	Target Neighborhood Hits	279	Shared Neighborhood Hits	19
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

K1543_MOUSE
θ value	5.27518 (rank : 129)	NC score	0.037942 (rank : 124)
Query Neighborhood Hits	178	Target Neighborhood Hits	497	Shared Neighborhood Hits	47
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

K1802_MOUSE
θ value	5.27518 (rank : 130)	NC score	0.038252 (rank : 121)
Query Neighborhood Hits	178	Target Neighborhood Hits	1596	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

NCOR2_HUMAN
θ value	5.27518 (rank : 131)	NC score	0.030945 (rank : 135)
Query Neighborhood Hits	178	Target Neighborhood Hits	870	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

PAX2_HUMAN
θ value	5.27518 (rank : 132)	NC score	0.009294 (rank : 210)
Query Neighborhood Hits	178	Target Neighborhood Hits	84	Shared Neighborhood Hits	5
SwissProt Accessions	Q02962, Q15105, Q15110, Q15837	Gene names	PAX2
Domain Architecture
Description	Paired box protein Pax-2.

PAX2_MOUSE
θ value	5.27518 (rank : 133)	NC score	0.009173 (rank : 211)
Query Neighborhood Hits	178	Target Neighborhood Hits	86	Shared Neighborhood Hits	4
SwissProt Accessions	P32114	Gene names	Pax2, Pax-2
Domain Architecture
Description	Paired box protein Pax-2.

PRGC2_MOUSE
θ value	5.27518 (rank : 134)	NC score	0.016492 (rank : 185)
Query Neighborhood Hits	178	Target Neighborhood Hits	225	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

RP1L1_HUMAN
θ value	5.27518 (rank : 135)	NC score	0.034191 (rank : 131)
Query Neighborhood Hits	178	Target Neighborhood Hits	1072	Shared Neighborhood Hits	54
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SEM5B_HUMAN
θ value	5.27518 (rank : 136)	NC score	0.001960 (rank : 231)
Query Neighborhood Hits	178	Target Neighborhood Hits	178	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

SFR14_MOUSE
θ value	5.27518 (rank : 137)	NC score	0.022388 (rank : 159)
Query Neighborhood Hits	178	Target Neighborhood Hits	238	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CH09, Q6PG19, Q80UY8, Q8BY32, Q8CFM0	Gene names	Sfrs14
Domain Architecture	No domain graphic available
Description	Putative splicing factor, arginine/serine-rich 14 (Arginine/serine- rich-splicing factor 14).

TIF1G_HUMAN
θ value	5.27518 (rank : 138)	NC score	0.018991 (rank : 178)
Query Neighborhood Hits	178	Target Neighborhood Hits	410	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

ULK4_MOUSE
θ value	5.27518 (rank : 139)	NC score	0.002847 (rank : 229)
Query Neighborhood Hits	178	Target Neighborhood Hits	793	Shared Neighborhood Hits	7
SwissProt Accessions	Q3V129, Q2VP87, Q32LZ6, Q8BLS0, Q8C8Z5, Q9D4H6	Gene names	Ulk4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4).

ZIMP7_MOUSE
θ value	5.27518 (rank : 140)	NC score	0.028861 (rank : 138)
Query Neighborhood Hits	178	Target Neighborhood Hits	566	Shared Neighborhood Hits	39
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ANR11_HUMAN
θ value	6.88961 (rank : 141)	NC score	0.015295 (rank : 190)
Query Neighborhood Hits	178	Target Neighborhood Hits	1289	Shared Neighborhood Hits	49
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ATBF1_HUMAN
θ value	6.88961 (rank : 142)	NC score	0.004690 (rank : 224)
Query Neighborhood Hits	178	Target Neighborhood Hits	1547	Shared Neighborhood Hits	43
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

B2L13_MOUSE
θ value	6.88961 (rank : 143)	NC score	0.021032 (rank : 165)
Query Neighborhood Hits	178	Target Neighborhood Hits	58	Shared Neighborhood Hits	9
SwissProt Accessions	P59017	Gene names	Bcl2l13, Mil1
Domain Architecture	No domain graphic available
Description	Bcl-2-like 13 protein (Protein Mil1) (Bcl-rambo).

BRE1B_MOUSE
θ value	6.88961 (rank : 144)	NC score	0.008923 (rank : 212)
Query Neighborhood Hits	178	Target Neighborhood Hits	970	Shared Neighborhood Hits	20
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

CAC1A_HUMAN
θ value	6.88961 (rank : 145)	NC score	0.011736 (rank : 202)
Query Neighborhood Hits	178	Target Neighborhood Hits	387	Shared Neighborhood Hits	32
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CHD1_HUMAN
θ value	6.88961 (rank : 146)	NC score	0.004500 (rank : 225)
Query Neighborhood Hits	178	Target Neighborhood Hits	337	Shared Neighborhood Hits	9
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

FOG1_HUMAN
θ value	6.88961 (rank : 147)	NC score	0.008108 (rank : 213)
Query Neighborhood Hits	178	Target Neighborhood Hits	981	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GA2L1_HUMAN
θ value	6.88961 (rank : 148)	NC score	0.016807 (rank : 183)
Query Neighborhood Hits	178	Target Neighborhood Hits	177	Shared Neighborhood Hits	19
SwissProt Accessions	Q99501, Q53EN7, Q92640, Q9BUY9	Gene names	GAS2L1, GAR22
Domain Architecture
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1) (GAS2-related protein on chromosome 22) (GAR22 protein).

GATA5_MOUSE
θ value	6.88961 (rank : 149)	NC score	0.007589 (rank : 215)
Query Neighborhood Hits	178	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	P97489	Gene names	Gata5
Domain Architecture
Description	Transcription factor GATA-5 (GATA-binding factor 5).

NSD1_MOUSE
θ value	6.88961 (rank : 150)	NC score	0.022396 (rank : 158)
Query Neighborhood Hits	178	Target Neighborhood Hits	472	Shared Neighborhood Hits	34
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

SCN9A_HUMAN
θ value	6.88961 (rank : 151)	NC score	0.005063 (rank : 223)
Query Neighborhood Hits	178	Target Neighborhood Hits	157	Shared Neighborhood Hits	6
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

SPR2D_MOUSE
θ value	6.88961 (rank : 152)	NC score	0.024208 (rank : 153)
Query Neighborhood Hits	178	Target Neighborhood Hits	61	Shared Neighborhood Hits	8
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SRRM1_MOUSE
θ value	6.88961 (rank : 153)	NC score	0.056519 (rank : 86)
Query Neighborhood Hits	178	Target Neighborhood Hits	966	Shared Neighborhood Hits	70
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

U383_HUMAN
θ value	6.88961 (rank : 154)	NC score	0.012420 (rank : 198)
Query Neighborhood Hits	178	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IYL2	Gene names	C4orf23
Domain Architecture	No domain graphic available
Description	Putative methyltransferase UPF0383 (EC 2.1.1.-).

ZN385_HUMAN
θ value	6.88961 (rank : 155)	NC score	0.020436 (rank : 169)
Query Neighborhood Hits	178	Target Neighborhood Hits	614	Shared Neighborhood Hits	35
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

AB1IP_MOUSE
θ value	8.99809 (rank : 156)	NC score	0.042946 (rank : 114)
Query Neighborhood Hits	178	Target Neighborhood Hits	181	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

CBP_HUMAN
θ value	8.99809 (rank : 157)	NC score	0.034157 (rank : 132)
Query Neighborhood Hits	178	Target Neighborhood Hits	941	Shared Neighborhood Hits	55
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CI114_HUMAN
θ value	8.99809 (rank : 158)	NC score	0.011423 (rank : 204)
Query Neighborhood Hits	178	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q5T280, Q6P469, Q6PGP9, Q6PIJ1, Q6PJV9	Gene names	C9orf114
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf114.

CQ028_HUMAN
θ value	8.99809 (rank : 159)	NC score	0.010208 (rank : 207)
Query Neighborhood Hits	178	Target Neighborhood Hits	56	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IV36, Q8N5L6, Q8TE83, Q9NT34	Gene names	C17orf28, DMC1
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 (Down-regulated in multiple cancers- 1).

CUTL2_HUMAN
θ value	8.99809 (rank : 160)	NC score	0.016059 (rank : 187)
Query Neighborhood Hits	178	Target Neighborhood Hits	906	Shared Neighborhood Hits	36
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

DNL1_HUMAN
θ value	8.99809 (rank : 161)	NC score	0.019858 (rank : 175)
Query Neighborhood Hits	178	Target Neighborhood Hits	216	Shared Neighborhood Hits	23
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

DYNA_MOUSE
θ value	8.99809 (rank : 162)	NC score	0.014628 (rank : 194)
Query Neighborhood Hits	178	Target Neighborhood Hits	1084	Shared Neighborhood Hits	36
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

E41L2_MOUSE
θ value	8.99809 (rank : 163)	NC score	0.005132 (rank : 222)
Query Neighborhood Hits	178	Target Neighborhood Hits	459	Shared Neighborhood Hits	15
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

EPN3_MOUSE
θ value	8.99809 (rank : 164)	NC score	0.014543 (rank : 195)
Query Neighborhood Hits	178	Target Neighborhood Hits	312	Shared Neighborhood Hits	31
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

ESX1L_HUMAN
θ value	8.99809 (rank : 165)	NC score	0.006696 (rank : 217)
Query Neighborhood Hits	178	Target Neighborhood Hits	498	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

FGD5_MOUSE
θ value	8.99809 (rank : 166)	NC score	0.038492 (rank : 120)
Query Neighborhood Hits	178	Target Neighborhood Hits	170	Shared Neighborhood Hits	23
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

FGD6_MOUSE
θ value	8.99809 (rank : 167)	NC score	0.045913 (rank : 110)
Query Neighborhood Hits	178	Target Neighborhood Hits	282	Shared Neighborhood Hits	34
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

FOXC2_HUMAN
θ value	8.99809 (rank : 168)	NC score	0.002324 (rank : 230)
Query Neighborhood Hits	178	Target Neighborhood Hits	236	Shared Neighborhood Hits	10
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

K0460_MOUSE
θ value	8.99809 (rank : 169)	NC score	0.017753 (rank : 181)
Query Neighborhood Hits	178	Target Neighborhood Hits	374	Shared Neighborhood Hits	24
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

NFAC2_MOUSE
θ value	8.99809 (rank : 170)	NC score	0.011307 (rank : 205)
Query Neighborhood Hits	178	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q60591, Q60984, Q60985	Gene names	Nfatc2, Nfat1, Nfatp
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

PO6F1_MOUSE
θ value	8.99809 (rank : 171)	NC score	0.005206 (rank : 221)
Query Neighborhood Hits	178	Target Neighborhood Hits	581	Shared Neighborhood Hits	23
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

RHG09_HUMAN
θ value	8.99809 (rank : 172)	NC score	0.021237 (rank : 164)
Query Neighborhood Hits	178	Target Neighborhood Hits	186	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

SEZ6L_HUMAN
θ value	8.99809 (rank : 173)	NC score	0.015867 (rank : 189)
Query Neighborhood Hits	178	Target Neighborhood Hits	289	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SPAG1_HUMAN
θ value	8.99809 (rank : 174)	NC score	0.006338 (rank : 219)
Query Neighborhood Hits	178	Target Neighborhood Hits	197	Shared Neighborhood Hits	6
SwissProt Accessions	Q07617, Q7Z5G1	Gene names	SPAG1
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (HSD-3.8).

SRRM2_MOUSE
θ value	8.99809 (rank : 175)	NC score	0.048057 (rank : 105)
Query Neighborhood Hits	178	Target Neighborhood Hits	1470	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TCOF_HUMAN
θ value	8.99809 (rank : 176)	NC score	0.047982 (rank : 106)
Query Neighborhood Hits	178	Target Neighborhood Hits	543	Shared Neighborhood Hits	45
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TENS1_HUMAN
θ value	8.99809 (rank : 177)	NC score	0.017670 (rank : 182)
Query Neighborhood Hits	178	Target Neighborhood Hits	400	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

ZBTB4_HUMAN
θ value	8.99809 (rank : 178)	NC score	0.001776 (rank : 232)
Query Neighborhood Hits	178	Target Neighborhood Hits	926	Shared Neighborhood Hits	21
SwissProt Accessions	Q9P1Z0, Q7Z697, Q86XJ4, Q8N4V8	Gene names	ZBTB4, KIAA1538
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1).

3BP2_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.113950 (rank : 44)
Query Neighborhood Hits	178	Target Neighborhood Hits	296	Shared Neighborhood Hits	32
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

3BP2_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.112641 (rank : 45)
Query Neighborhood Hits	178	Target Neighborhood Hits	142	Shared Neighborhood Hits	21
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

ACTN1_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.059514 (rank : 73)
Query Neighborhood Hits	178	Target Neighborhood Hits	221	Shared Neighborhood Hits	6
SwissProt Accessions	P12814, Q9BTN1	Gene names	ACTN1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN1_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.059715 (rank : 71)
Query Neighborhood Hits	178	Target Neighborhood Hits	216	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TPR4	Gene names	Actn1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN2_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.058695 (rank : 80)
Query Neighborhood Hits	178	Target Neighborhood Hits	295	Shared Neighborhood Hits	11
SwissProt Accessions	P35609, Q86TF4, Q86TI8	Gene names	ACTN2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

ACTN2_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.058502 (rank : 81)
Query Neighborhood Hits	178	Target Neighborhood Hits	287	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JI91	Gene names	Actn2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

ACTN3_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.058945 (rank : 78)
Query Neighborhood Hits	178	Target Neighborhood Hits	272	Shared Neighborhood Hits	6
SwissProt Accessions	Q08043	Gene names	ACTN3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ACTN3_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.059137 (rank : 75)
Query Neighborhood Hits	178	Target Neighborhood Hits	265	Shared Neighborhood Hits	10
SwissProt Accessions	O88990	Gene names	Actn3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ACTN4_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.059110 (rank : 76)
Query Neighborhood Hits	178	Target Neighborhood Hits	279	Shared Neighborhood Hits	8
SwissProt Accessions	O43707, O76048	Gene names	ACTN4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ACTN4_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.059069 (rank : 77)
Query Neighborhood Hits	178	Target Neighborhood Hits	276	Shared Neighborhood Hits	8
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ANLN_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.109604 (rank : 47)
Query Neighborhood Hits	178	Target Neighborhood Hits	222	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

ANLN_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.089868 (rank : 50)
Query Neighborhood Hits	178	Target Neighborhood Hits	297	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

BASP_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.058423 (rank : 82)
Query Neighborhood Hits	178	Target Neighborhood Hits	321	Shared Neighborhood Hits	32
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.058744 (rank : 79)
Query Neighborhood Hits	178	Target Neighborhood Hits	260	Shared Neighborhood Hits	25
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CENB2_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.062667 (rank : 67)
Query Neighborhood Hits	178	Target Neighborhood Hits	425	Shared Neighborhood Hits	22
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB5_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.056805 (rank : 85)
Query Neighborhood Hits	178	Target Neighborhood Hits	395	Shared Neighborhood Hits	19
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CLMN_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.061449 (rank : 68)
Query Neighborhood Hits	178	Target Neighborhood Hits	205	Shared Neighborhood Hits	12
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

CLMN_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.062799 (rank : 66)
Query Neighborhood Hits	178	Target Neighborhood Hits	180	Shared Neighborhood Hits	13
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

CNKR2_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.122652 (rank : 40)
Query Neighborhood Hits	178	Target Neighborhood Hits	197	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.123661 (rank : 39)
Query Neighborhood Hits	178	Target Neighborhood Hits	197	Shared Neighborhood Hits	30
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

DAPP1_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.098579 (rank : 49)
Query Neighborhood Hits	178	Target Neighborhood Hits	227	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.103760 (rank : 48)
Query Neighborhood Hits	178	Target Neighborhood Hits	225	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DYN2_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.052438 (rank : 98)
Query Neighborhood Hits	178	Target Neighborhood Hits	112	Shared Neighborhood Hits	24
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

DYN2_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.051270 (rank : 100)
Query Neighborhood Hits	178	Target Neighborhood Hits	104	Shared Neighborhood Hits	25
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

DYN3_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.056115 (rank : 88)
Query Neighborhood Hits	178	Target Neighborhood Hits	158	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

GNRP_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.059447 (rank : 74)
Query Neighborhood Hits	178	Target Neighborhood Hits	239	Shared Neighborhood Hits	22
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

GNRP_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.057687 (rank : 84)
Query Neighborhood Hits	178	Target Neighborhood Hits	191	Shared Neighborhood Hits	21
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

MARCS_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.053073 (rank : 95)
Query Neighborhood Hits	178	Target Neighborhood Hits	204	Shared Neighborhood Hits	23
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MILK2_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.076294 (rank : 57)
Query Neighborhood Hits	178	Target Neighborhood Hits	457	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

PHLB1_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.053023 (rank : 96)
Query Neighborhood Hits	178	Target Neighborhood Hits	1038	Shared Neighborhood Hits	64
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PKHA1_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.144063 (rank : 30)
Query Neighborhood Hits	178	Target Neighborhood Hits	127	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.139487 (rank : 32)
Query Neighborhood Hits	178	Target Neighborhood Hits	120	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA2_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.111928 (rank : 46)
Query Neighborhood Hits	178	Target Neighborhood Hits	119	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PKHA2_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.128001 (rank : 37)
Query Neighborhood Hits	178	Target Neighborhood Hits	116	Shared Neighborhood Hits	24
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PKHA4_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.134379 (rank : 34)
Query Neighborhood Hits	178	Target Neighborhood Hits	283	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA4_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.138389 (rank : 33)
Query Neighborhood Hits	178	Target Neighborhood Hits	202	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHB1_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.050476 (rank : 102)
Query Neighborhood Hits	178	Target Neighborhood Hits	46	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UF11, Q9UBF5, Q9UI37, Q9UI44	Gene names	PLEKHB1, KPL1, PHR1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

PKHB2_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.054262 (rank : 91)
Query Neighborhood Hits	178	Target Neighborhood Hits	54	Shared Neighborhood Hits	13
SwissProt Accessions	Q96CS7, Q86W37, Q9BV75, Q9NWK1	Gene names	PLEKHB2, EVT2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

PKHB2_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.053687 (rank : 94)
Query Neighborhood Hits	178	Target Neighborhood Hits	48	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QZC7, Q3UDH6, Q8C4I4, Q8CA27	Gene names	Plekhb2, Evt2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

PLEK2_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.114322 (rank : 43)
Query Neighborhood Hits	178	Target Neighborhood Hits	101	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.115396 (rank : 42)
Query Neighborhood Hits	178	Target Neighborhood Hits	96	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PRP1_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.056085 (rank : 89)
Query Neighborhood Hits	178	Target Neighborhood Hits	385	Shared Neighborhood Hits	44
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

RASA1_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.071185 (rank : 62)
Query Neighborhood Hits	178	Target Neighborhood Hits	258	Shared Neighborhood Hits	16
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RHG25_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.074259 (rank : 61)
Query Neighborhood Hits	178	Target Neighborhood Hits	550	Shared Neighborhood Hits	32
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.080293 (rank : 56)
Query Neighborhood Hits	178	Target Neighborhood Hits	492	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SMOO_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.076121 (rank : 58)
Query Neighborhood Hits	178	Target Neighborhood Hits	391	Shared Neighborhood Hits	43
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

SPTA1_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.059588 (rank : 72)
Query Neighborhood Hits	178	Target Neighborhood Hits	748	Shared Neighborhood Hits	13
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTA1_MOUSE
θ value	θ > 10 (rank : 226)	NC score	0.060993 (rank : 70)
Query Neighborhood Hits	178	Target Neighborhood Hits	675	Shared Neighborhood Hits	14
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTA2_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.056278 (rank : 87)
Query Neighborhood Hits	178	Target Neighborhood Hits	888	Shared Neighborhood Hits	15
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

SPTB1_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.083433 (rank : 54)
Query Neighborhood Hits	178	Target Neighborhood Hits	541	Shared Neighborhood Hits	13
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

SPTB1_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.082870 (rank : 55)
Query Neighborhood Hits	178	Target Neighborhood Hits	543	Shared Neighborhood Hits	17
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

SPTN5_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.075051 (rank : 60)
Query Neighborhood Hits	178	Target Neighborhood Hits	674	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

SWP70_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.075512 (rank : 59)
Query Neighborhood Hits	178	Target Neighborhood Hits	973	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.067136 (rank : 64)
Query Neighborhood Hits	178	Target Neighborhood Hits	1097	Shared Neighborhood Hits	36
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

TMAP1_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.050609 (rank : 101)
Query Neighborhood Hits	178	Target Neighborhood Hits	140	Shared Neighborhood Hits	21
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

Hits sorted by NC score

PSD4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	178	Target Neighborhood Hits	178	Shared Neighborhood Hits	178
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

PSD4_MOUSE
NC score	0.970280 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	178	Target Neighborhood Hits	78	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44	Gene names	Psd4
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).

PSD3_HUMAN
NC score	0.938976 (rank : 3)	θ value	1.69605e-115 (rank : 3)
Query Neighborhood Hits	178	Target Neighborhood Hits	75	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NYI0, Q9Y2F1	Gene names	PSD3, EFA6R, HCA67, KIAA0942
Domain Architecture
Description	PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).

CYH2_HUMAN
NC score	0.720829 (rank : 4)	θ value	2.35151e-24 (rank : 8)
Query Neighborhood Hits	178	Target Neighborhood Hits	175	Shared Neighborhood Hits	34
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
NC score	0.719762 (rank : 5)	θ value	1.16704e-23 (rank : 9)
Query Neighborhood Hits	178	Target Neighborhood Hits	171	Shared Neighborhood Hits	34
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH3_HUMAN
NC score	0.719671 (rank : 6)	θ value	8.08199e-25 (rank : 6)
Query Neighborhood Hits	178	Target Neighborhood Hits	137	Shared Neighborhood Hits	35
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH1_MOUSE
NC score	0.717936 (rank : 7)	θ value	3.62785e-25 (rank : 5)
Query Neighborhood Hits	178	Target Neighborhood Hits	176	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH3_MOUSE
NC score	0.716163 (rank : 8)	θ value	7.30988e-26 (rank : 4)
Query Neighborhood Hits	178	Target Neighborhood Hits	148	Shared Neighborhood Hits	36
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

CYH1_HUMAN
NC score	0.714782 (rank : 9)	θ value	2.35151e-24 (rank : 7)
Query Neighborhood Hits	178	Target Neighborhood Hits	184	Shared Neighborhood Hits	35
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

GBF1_HUMAN
NC score	0.714305 (rank : 10)	θ value	3.63628e-17 (rank : 18)
Query Neighborhood Hits	178	Target Neighborhood Hits	142	Shared Neighborhood Hits	36
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

CYH4_MOUSE
NC score	0.714060 (rank : 11)	θ value	3.17815e-21 (rank : 10)
Query Neighborhood Hits	178	Target Neighborhood Hits	134	Shared Neighborhood Hits	35
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

CYH4_HUMAN
NC score	0.713559 (rank : 12)	θ value	4.15078e-21 (rank : 11)
Query Neighborhood Hits	178	Target Neighborhood Hits	135	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

IQEC3_HUMAN
NC score	0.700195 (rank : 13)	θ value	1.63225e-17 (rank : 16)
Query Neighborhood Hits	178	Target Neighborhood Hits	125	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

BIG1_HUMAN
NC score	0.699196 (rank : 14)	θ value	7.82807e-20 (rank : 12)
Query Neighborhood Hits	178	Target Neighborhood Hits	76	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

IQEC3_MOUSE
NC score	0.696952 (rank : 15)	θ value	1.63225e-17 (rank : 17)
Query Neighborhood Hits	178	Target Neighborhood Hits	274	Shared Neighborhood Hits	46
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IQEC1_MOUSE
NC score	0.691505 (rank : 16)	θ value	1.92812e-18 (rank : 14)
Query Neighborhood Hits	178	Target Neighborhood Hits	54	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R0S2, Q3TZC3, Q5DU15	Gene names	Iqsec1, Kiaa0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1.

IQEC1_HUMAN
NC score	0.691223 (rank : 17)	θ value	6.62687e-19 (rank : 13)
Query Neighborhood Hits	178	Target Neighborhood Hits	76	Shared Neighborhood Hits	25
SwissProt Accessions	Q6DN90, O94863, Q96D85	Gene names	IQSEC1, ARFGEP100, BRAG2, KIAA0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein).

BIG2_HUMAN
NC score	0.687635 (rank : 18)	θ value	1.63225e-17 (rank : 15)
Query Neighborhood Hits	178	Target Neighborhood Hits	66	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

IQEC2_MOUSE
NC score	0.658556 (rank : 19)	θ value	3.07829e-16 (rank : 19)
Query Neighborhood Hits	178	Target Neighborhood Hits	417	Shared Neighborhood Hits	51
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_HUMAN
NC score	0.656997 (rank : 20)	θ value	6.85773e-16 (rank : 20)
Query Neighborhood Hits	178	Target Neighborhood Hits	403	Shared Neighborhood Hits	50
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

FBX8_MOUSE
NC score	0.614194 (rank : 21)	θ value	9.92553e-07 (rank : 26)
Query Neighborhood Hits	178	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QZN3	Gene names	Fbxo8, Fbx8
Domain Architecture
Description	F-box only protein 8.

FBX8_HUMAN
NC score	0.612871 (rank : 22)	θ value	9.92553e-07 (rank : 25)
Query Neighborhood Hits	178	Target Neighborhood Hits	44	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NRD0, Q6UWN4, Q9NRP5, Q9UKC4	Gene names	FBXO8, FBS, FBX8
Domain Architecture
Description	F-box only protein 8 (F-box/SEC7 protein FBS).

CNKR1_HUMAN
NC score	0.266161 (rank : 23)	θ value	0.000270298 (rank : 28)
Query Neighborhood Hits	178	Target Neighborhood Hits	154	Shared Neighborhood Hits	34
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

PKHA6_HUMAN
NC score	0.207145 (rank : 24)	θ value	0.0961366 (rank : 41)
Query Neighborhood Hits	178	Target Neighborhood Hits	556	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
NC score	0.201690 (rank : 25)	θ value	0.365318 (rank : 53)
Query Neighborhood Hits	178	Target Neighborhood Hits	591	Shared Neighborhood Hits	53
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PLEK_HUMAN
NC score	0.185205 (rank : 26)	θ value	0.47712 (rank : 55)
Query Neighborhood Hits	178	Target Neighborhood Hits	110	Shared Neighborhood Hits	25
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PLEK_MOUSE
NC score	0.181883 (rank : 27)	θ value	0.0961366 (rank : 42)
Query Neighborhood Hits	178	Target Neighborhood Hits	109	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

SPTN2_HUMAN
NC score	0.155490 (rank : 28)	θ value	1.33837e-11 (rank : 21)
Query Neighborhood Hits	178	Target Neighborhood Hits	535	Shared Neighborhood Hits	30
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

PKHA5_HUMAN
NC score	0.147481 (rank : 29)	θ value	0.125558 (rank : 45)
Query Neighborhood Hits	178	Target Neighborhood Hits	455	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PKHA1_HUMAN
NC score	0.144063 (rank : 30)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	178	Target Neighborhood Hits	127	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

SPTN4_HUMAN
NC score	0.141939 (rank : 31)	θ value	3.41135e-07 (rank : 24)
Query Neighborhood Hits	178	Target Neighborhood Hits	570	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

PKHA1_MOUSE
NC score	0.139487 (rank : 32)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	178	Target Neighborhood Hits	120	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA4_MOUSE
NC score	0.138389 (rank : 33)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	178	Target Neighborhood Hits	202	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA4_HUMAN
NC score	0.134379 (rank : 34)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	178	Target Neighborhood Hits	283	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

SPTB2_MOUSE
NC score	0.132099 (rank : 35)	θ value	2.13673e-09 (rank : 22)
Query Neighborhood Hits	178	Target Neighborhood Hits	770	Shared Neighborhood Hits	35
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTB2_HUMAN
NC score	0.131100 (rank : 36)	θ value	3.64472e-09 (rank : 23)
Query Neighborhood Hits	178	Target Neighborhood Hits	748	Shared Neighborhood Hits	33
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

PKHA2_MOUSE
NC score	0.128001 (rank : 37)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	178	Target Neighborhood Hits	116	Shared Neighborhood Hits	24
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

TIAM1_HUMAN
NC score	0.124864 (rank : 38)	θ value	0.00102713 (rank : 30)
Query Neighborhood Hits	178	Target Neighborhood Hits	225	Shared Neighborhood Hits	23
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

CNKR2_MOUSE
NC score	0.123661 (rank : 39)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	178	Target Neighborhood Hits	197	Shared Neighborhood Hits	30
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.122652 (rank : 40)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	178	Target Neighborhood Hits	197	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

TIAM1_MOUSE
NC score	0.118891 (rank : 41)	θ value	0.00390308 (rank : 31)
Query Neighborhood Hits	178	Target Neighborhood Hits	205	Shared Neighborhood Hits	20
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

PLEK2_MOUSE
NC score	0.115396 (rank : 42)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	178	Target Neighborhood Hits	96	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_HUMAN
NC score	0.114322 (rank : 43)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	178	Target Neighborhood Hits	101	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

3BP2_HUMAN
NC score	0.113950 (rank : 44)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	178	Target Neighborhood Hits	296	Shared Neighborhood Hits	32
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

3BP2_MOUSE
NC score	0.112641 (rank : 45)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	178	Target Neighborhood Hits	142	Shared Neighborhood Hits	21
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

PKHA2_HUMAN
NC score	0.111928 (rank : 46)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	178	Target Neighborhood Hits	119	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

ANLN_HUMAN
NC score	0.109604 (rank : 47)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	178	Target Neighborhood Hits	222	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

DAPP1_MOUSE
NC score	0.103760 (rank : 48)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	178	Target Neighborhood Hits	225	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_HUMAN
NC score	0.098579 (rank : 49)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	178	Target Neighborhood Hits	227	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

ANLN_MOUSE
NC score	0.089868 (rank : 50)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	178	Target Neighborhood Hits	297	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

MILK1_MOUSE
NC score	0.087679 (rank : 51)	θ value	1.81305 (rank : 78)
Query Neighborhood Hits	178	Target Neighborhood Hits	788	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

CN155_HUMAN
NC score	0.086595 (rank : 52)	θ value	0.279714 (rank : 49)
Query Neighborhood Hits	178	Target Neighborhood Hits	385	Shared Neighborhood Hits	36
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

MILK1_HUMAN
NC score	0.085167 (rank : 53)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	178	Target Neighborhood Hits	427	Shared Neighborhood Hits	45
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

SPTB1_HUMAN
NC score	0.083433 (rank : 54)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	178	Target Neighborhood Hits	541	Shared Neighborhood Hits	13
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

SPTB1_MOUSE
NC score	0.082870 (rank : 55)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	178	Target Neighborhood Hits	543	Shared Neighborhood Hits	17
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

RHG25_MOUSE
NC score	0.080293 (rank : 56)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	178	Target Neighborhood Hits	492	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

MILK2_HUMAN
NC score	0.076294 (rank : 57)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	178	Target Neighborhood Hits	457	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

SMOO_HUMAN
NC score	0.076121 (rank : 58)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	178	Target Neighborhood Hits	391	Shared Neighborhood Hits	43
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

SWP70_HUMAN
NC score	0.075512 (rank : 59)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	178	Target Neighborhood Hits	973	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SPTN5_HUMAN
NC score	0.075051 (rank : 60)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	178	Target Neighborhood Hits	674	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

RHG25_HUMAN
NC score	0.074259 (rank : 61)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	178	Target Neighborhood Hits	550	Shared Neighborhood Hits	32
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RASA1_HUMAN
NC score	0.071185 (rank : 62)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	178	Target Neighborhood Hits	258	Shared Neighborhood Hits	16
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

TARA_MOUSE
NC score	0.068546 (rank : 63)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	178	Target Neighborhood Hits	1133	Shared Neighborhood Hits	63
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SWP70_MOUSE
NC score	0.067136 (rank : 64)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	178	Target Neighborhood Hits	1097	Shared Neighborhood Hits	36
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SET1A_HUMAN
NC score	0.063413 (rank : 65)	θ value	0.0563607 (rank : 38)
Query Neighborhood Hits	178	Target Neighborhood Hits	690	Shared Neighborhood Hits	50
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

CLMN_MOUSE
NC score	0.062799 (rank : 66)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	178	Target Neighborhood Hits	180	Shared Neighborhood Hits	13
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

CENB2_HUMAN
NC score	0.062667 (rank : 67)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	178	Target Neighborhood Hits	425	Shared Neighborhood Hits	22
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CLMN_HUMAN
NC score	0.061449 (rank : 68)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	178	Target Neighborhood Hits	205	Shared Neighborhood Hits	12
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

OGFR_HUMAN
NC score	0.061017 (rank : 69)	θ value	0.163984 (rank : 47)
Query Neighborhood Hits	178	Target Neighborhood Hits	1582	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SPTA1_MOUSE
NC score	0.060993 (rank : 70)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	178	Target Neighborhood Hits	675	Shared Neighborhood Hits	14
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

ACTN1_MOUSE
NC score	0.059715 (rank : 71)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	178	Target Neighborhood Hits	216	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TPR4	Gene names	Actn1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

SPTA1_HUMAN
NC score	0.059588 (rank : 72)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	178	Target Neighborhood Hits	748	Shared Neighborhood Hits	13
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

ACTN1_HUMAN
NC score	0.059514 (rank : 73)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	178	Target Neighborhood Hits	221	Shared Neighborhood Hits	6
SwissProt Accessions	P12814, Q9BTN1	Gene names	ACTN1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

GNRP_HUMAN
NC score	0.059447 (rank : 74)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	178	Target Neighborhood Hits	239	Shared Neighborhood Hits	22
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

ACTN3_MOUSE
NC score	0.059137 (rank : 75)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	178	Target Neighborhood Hits	265	Shared Neighborhood Hits	10
SwissProt Accessions	O88990	Gene names	Actn3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ACTN4_HUMAN
NC score	0.059110 (rank : 76)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	178	Target Neighborhood Hits	279	Shared Neighborhood Hits	8
SwissProt Accessions	O43707, O76048	Gene names	ACTN4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ACTN4_MOUSE
NC score	0.059069 (rank : 77)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	178	Target Neighborhood Hits	276	Shared Neighborhood Hits	8
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ACTN3_HUMAN
NC score	0.058945 (rank : 78)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	178	Target Neighborhood Hits	272	Shared Neighborhood Hits	6
SwissProt Accessions	Q08043	Gene names	ACTN3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

BASP_MOUSE
NC score	0.058744 (rank : 79)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	178	Target Neighborhood Hits	260	Shared Neighborhood Hits	25
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

ACTN2_HUMAN
NC score	0.058695 (rank : 80)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	178	Target Neighborhood Hits	295	Shared Neighborhood Hits	11
SwissProt Accessions	P35609, Q86TF4, Q86TI8	Gene names	ACTN2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

ACTN2_MOUSE
NC score	0.058502 (rank : 81)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	178	Target Neighborhood Hits	287	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JI91	Gene names	Actn2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

BASP_HUMAN
NC score	0.058423 (rank : 82)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	178	Target Neighborhood Hits	321	Shared Neighborhood Hits	32
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

TARA_HUMAN
NC score	0.057876 (rank : 83)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	178	Target Neighborhood Hits	1626	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

GNRP_MOUSE
NC score	0.057687 (rank : 84)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	178	Target Neighborhood Hits	191	Shared Neighborhood Hits	21
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

CENB5_HUMAN
NC score	0.056805 (rank : 85)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	178	Target Neighborhood Hits	395	Shared Neighborhood Hits	19
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

SRRM1_MOUSE
NC score	0.056519 (rank : 86)	θ value	6.88961 (rank : 153)
Query Neighborhood Hits	178	Target Neighborhood Hits	966	Shared Neighborhood Hits	70
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SPTA2_HUMAN
NC score	0.056278 (rank : 87)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	178	Target Neighborhood Hits	888	Shared Neighborhood Hits	15
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

DYN3_HUMAN
NC score	0.056115 (rank : 88)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	178	Target Neighborhood Hits	158	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

PRP1_HUMAN
NC score	0.056085 (rank : 89)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	178	Target Neighborhood Hits	385	Shared Neighborhood Hits	44
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

SRRM2_HUMAN
NC score	0.054389 (rank : 90)	θ value	4.03905 (rank : 123)
Query Neighborhood Hits	178	Target Neighborhood Hits	1296	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

PKHB2_HUMAN
NC score	0.054262 (rank : 91)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	178	Target Neighborhood Hits	54	Shared Neighborhood Hits	13
SwissProt Accessions	Q96CS7, Q86W37, Q9BV75, Q9NWK1	Gene names	PLEKHB2, EVT2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

RGS3_MOUSE
NC score	0.054233 (rank : 92)	θ value	0.21417 (rank : 48)
Query Neighborhood Hits	178	Target Neighborhood Hits	1621	Shared Neighborhood Hits	92
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

NFH_MOUSE
NC score	0.054067 (rank : 93)	θ value	7.1131e-05 (rank : 27)
Query Neighborhood Hits	178	Target Neighborhood Hits	2247	Shared Neighborhood Hits	99
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PKHB2_MOUSE
NC score	0.053687 (rank : 94)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	178	Target Neighborhood Hits	48	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QZC7, Q3UDH6, Q8C4I4, Q8CA27	Gene names	Plekhb2, Evt2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

MARCS_HUMAN
NC score	0.053073 (rank : 95)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	178	Target Neighborhood Hits	204	Shared Neighborhood Hits	23
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

PHLB1_HUMAN
NC score	0.053023 (rank : 96)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	178	Target Neighborhood Hits	1038	Shared Neighborhood Hits	64
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

MLL2_HUMAN
NC score	0.053016 (rank : 97)	θ value	0.0330416 (rank : 35)
Query Neighborhood Hits	178	Target Neighborhood Hits	1788	Shared Neighborhood Hits	74
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

DYN2_HUMAN
NC score	0.052438 (rank : 98)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	178	Target Neighborhood Hits	112	Shared Neighborhood Hits	24
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

PRPC_HUMAN
NC score	0.052229 (rank : 99)	θ value	1.38821 (rank : 74)
Query Neighborhood Hits	178	Target Neighborhood Hits	165	Shared Neighborhood Hits	19
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

DYN2_MOUSE
NC score	0.051270 (rank : 100)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	178	Target Neighborhood Hits	104	Shared Neighborhood Hits	25
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

TMAP1_HUMAN
NC score	0.050609 (rank : 101)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	178	Target Neighborhood Hits	140	Shared Neighborhood Hits	21
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

PKHB1_HUMAN
NC score	0.050476 (rank : 102)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	178	Target Neighborhood Hits	46	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UF11, Q9UBF5, Q9UI37, Q9UI44	Gene names	PLEKHB1, KPL1, PHR1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

MUC1_HUMAN
NC score	0.048399 (rank : 103)	θ value	0.0252991 (rank : 34)
Query Neighborhood Hits	178	Target Neighborhood Hits	975	Shared Neighborhood Hits	59
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

CSF1_HUMAN
NC score	0.048080 (rank : 104)	θ value	0.163984 (rank : 46)
Query Neighborhood Hits	178	Target Neighborhood Hits	258	Shared Neighborhood Hits	24
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

SRRM2_MOUSE
NC score	0.048057 (rank : 105)	θ value	8.99809 (rank : 175)
Query Neighborhood Hits	178	Target Neighborhood Hits	1470	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TCOF_HUMAN
NC score	0.047982 (rank : 106)	θ value	8.99809 (rank : 176)
Query Neighborhood Hits	178	Target Neighborhood Hits	543	Shared Neighborhood Hits	45
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

FGD6_HUMAN
NC score	0.047744 (rank : 107)	θ value	1.06291 (rank : 66)
Query Neighborhood Hits	178	Target Neighborhood Hits	237	Shared Neighborhood Hits	24
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

BAT3_MOUSE
NC score	0.047084 (rank : 108)	θ value	1.06291 (rank : 65)
Query Neighborhood Hits	178	Target Neighborhood Hits	518	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

MAGE1_HUMAN
NC score	0.046686 (rank : 109)	θ value	0.0193708 (rank : 33)
Query Neighborhood Hits	178	Target Neighborhood Hits	1389	Shared Neighborhood Hits	82
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

FGD6_MOUSE
NC score	0.045913 (rank : 110)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	178	Target Neighborhood Hits	282	Shared Neighborhood Hits	34
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

PHAR2_HUMAN
NC score	0.044099 (rank : 111)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	178	Target Neighborhood Hits	208	Shared Neighborhood Hits	21
SwissProt Accessions	O75167, Q68DM2	Gene names	PHACTR2, C6orf56, KIAA0680
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 2.

RGS3_HUMAN
NC score	0.044083 (rank : 112)	θ value	2.36792 (rank : 92)
Query Neighborhood Hits	178	Target Neighborhood Hits	1375	Shared Neighborhood Hits	82
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

APXL_HUMAN
NC score	0.043084 (rank : 113)	θ value	0.813845 (rank : 61)
Query Neighborhood Hits	178	Target Neighborhood Hits	553	Shared Neighborhood Hits	37
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

AB1IP_MOUSE
NC score	0.042946 (rank : 114)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	178	Target Neighborhood Hits	181	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

EAN57_HUMAN
NC score	0.042606 (rank : 115)	θ value	0.365318 (rank : 51)
Query Neighborhood Hits	178	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	O43247, Q6ICF2, Q9Y4V8	Gene names	EAN57
Domain Architecture	No domain graphic available
Description	Protein EAN57.

SPR2F_MOUSE
NC score	0.041584 (rank : 116)	θ value	1.06291 (rank : 67)
Query Neighborhood Hits	178	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

SON_HUMAN
NC score	0.041493 (rank : 117)	θ value	0.62314 (rank : 59)
Query Neighborhood Hits	178	Target Neighborhood Hits	1568	Shared Neighborhood Hits	88
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

PI5PA_HUMAN
NC score	0.040365 (rank : 118)	θ value	0.62314 (rank : 58)
Query Neighborhood Hits	178	Target Neighborhood Hits	749	Shared Neighborhood Hits	57
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

CSPG5_MOUSE
NC score	0.038757 (rank : 119)	θ value	0.813845 (rank : 62)
Query Neighborhood Hits	178	Target Neighborhood Hits	211	Shared Neighborhood Hits	17
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

FGD5_MOUSE
NC score	0.038492 (rank : 120)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	178	Target Neighborhood Hits	170	Shared Neighborhood Hits	23
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

K1802_MOUSE
NC score	0.038252 (rank : 121)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	178	Target Neighborhood Hits	1596	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

K1802_HUMAN
NC score	0.038082 (rank : 122)	θ value	2.36792 (rank : 87)
Query Neighborhood Hits	178	Target Neighborhood Hits	1378	Shared Neighborhood Hits	62
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

AIM1_HUMAN
NC score	0.037996 (rank : 123)	θ value	2.36792 (rank : 82)
Query Neighborhood Hits	178	Target Neighborhood Hits	247	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

K1543_MOUSE
NC score	0.037942 (rank : 124)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	178	Target Neighborhood Hits	497	Shared Neighborhood Hits	47
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

RERE_HUMAN
NC score	0.037453 (rank : 125)	θ value	4.03905 (rank : 121)
Query Neighborhood Hits	178	Target Neighborhood Hits	779	Shared Neighborhood Hits	51
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SPR2I_MOUSE
NC score	0.037147 (rank : 126)	θ value	1.81305 (rank : 79)
Query Neighborhood Hits	178	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

FGD5_HUMAN
NC score	0.037038 (rank : 127)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	178	Target Neighborhood Hits	235	Shared Neighborhood Hits	23
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

CBP_MOUSE
NC score	0.035696 (rank : 128)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	178	Target Neighborhood Hits	1051	Shared Neighborhood Hits	59
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

AFF1_MOUSE
NC score	0.035580 (rank : 129)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	178	Target Neighborhood Hits	351	Shared Neighborhood Hits	33
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

CNOT3_MOUSE
NC score	0.034278 (rank : 130)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	178	Target Neighborhood Hits	504	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

RP1L1_HUMAN
NC score	0.034191 (rank : 131)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	178	Target Neighborhood Hits	1072	Shared Neighborhood Hits	54
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

CBP_HUMAN
NC score	0.034157 (rank : 132)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	178	Target Neighborhood Hits	941	Shared Neighborhood Hits	55
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DIDO1_HUMAN
NC score	0.033623 (rank : 133)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	178	Target Neighborhood Hits	960	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

SPR2E_MOUSE
NC score	0.032512 (rank : 134)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	178	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

NCOR2_HUMAN
NC score	0.030945 (rank : 135)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	178	Target Neighborhood Hits	870	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

OSB10_HUMAN
NC score	0.030378 (rank : 136)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	178	Target Neighborhood Hits	55	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BXB5, Q9BTU5	Gene names	OSBPL10, ORP10, OSBP9
Domain Architecture
Description	Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).

K1849_MOUSE
NC score	0.029670 (rank : 137)	θ value	0.0736092 (rank : 39)
Query Neighborhood Hits	178	Target Neighborhood Hits	335	Shared Neighborhood Hits	15
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

ZIMP7_MOUSE
NC score	0.028861 (rank : 138)	θ value	5.27518 (rank : 140)
Query Neighborhood Hits	178	Target Neighborhood Hits	566	Shared Neighborhood Hits	39
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

BTBDA_MOUSE
NC score	0.028328 (rank : 139)	θ value	2.36792 (rank : 84)
Query Neighborhood Hits	178	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q80X66	Gene names	Btbd10
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 10.

PDZD2_HUMAN
NC score	0.028062 (rank : 140)	θ value	1.38821 (rank : 73)
Query Neighborhood Hits	178	Target Neighborhood Hits	772	Shared Neighborhood Hits	49
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

MY18B_HUMAN
NC score	0.027691 (rank : 141)	θ value	0.0330416 (rank : 36)
Query Neighborhood Hits	178	Target Neighborhood Hits	1299	Shared Neighborhood Hits	51
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

WBS14_MOUSE
NC score	0.027489 (rank : 142)	θ value	3.0926 (rank : 110)
Query Neighborhood Hits	178	Target Neighborhood Hits	171	Shared Neighborhood Hits	17
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

NCA11_MOUSE
NC score	0.026086 (rank : 143)	θ value	0.62314 (rank : 56)
Query Neighborhood Hits	178	Target Neighborhood Hits	661	Shared Neighborhood Hits	35
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

CAC1G_HUMAN
NC score	0.025429 (rank : 144)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	178	Target Neighborhood Hits	587	Shared Neighborhood Hits	44
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

TIF1G_MOUSE
NC score	0.025221 (rank : 145)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	178	Target Neighborhood Hits	498	Shared Neighborhood Hits	34
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TNFC_MOUSE
NC score	0.025192 (rank : 146)	θ value	1.81305 (rank : 81)
Query Neighborhood Hits	178	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P41155	Gene names	Ltb, Tnfc, Tnfsf3
Domain Architecture
Description	Lymphotoxin-beta (LT-beta) (Tumor necrosis factor C) (TNF-C) (Tumor necrosis factor ligand superfamily member 3).

ZCPW1_MOUSE
NC score	0.025090 (rank : 147)	θ value	2.36792 (rank : 97)
Query Neighborhood Hits	178	Target Neighborhood Hits	307	Shared Neighborhood Hits	19
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

GLDN_MOUSE
NC score	0.025006 (rank : 148)	θ value	0.0563607 (rank : 37)
Query Neighborhood Hits	178	Target Neighborhood Hits	155	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BMF8, Q80ZC5	Gene names	Gldn, Crgl2
Domain Architecture	No domain graphic available
Description	Gliomedin (Cancer-related gene liver 2 protein) (CRG-L2).

SYN3_HUMAN
NC score	0.024602 (rank : 149)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	178	Target Neighborhood Hits	203	Shared Neighborhood Hits	28
SwissProt Accessions	O14994	Gene names	SYN3
Domain Architecture
Description	Synapsin-3 (Synapsin III).

TXLNB_HUMAN
NC score	0.024519 (rank : 150)	θ value	3.0926 (rank : 108)
Query Neighborhood Hits	178	Target Neighborhood Hits	912	Shared Neighborhood Hits	53
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

BTBDA_HUMAN
NC score	0.024493 (rank : 151)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	178	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BSF8, Q86WG1	Gene names	BTBD10
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 10.

CO027_HUMAN
NC score	0.024409 (rank : 152)	θ value	2.36792 (rank : 85)
Query Neighborhood Hits	178	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q2M3C6, Q8N993, Q96LL5	Gene names	C15orf27
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf27.

SPR2D_MOUSE
NC score	0.024208 (rank : 153)	θ value	6.88961 (rank : 152)
Query Neighborhood Hits	178	Target Neighborhood Hits	61	Shared Neighborhood Hits	8
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

TACC2_MOUSE
NC score	0.024171 (rank : 154)	θ value	1.81305 (rank : 80)
Query Neighborhood Hits	178	Target Neighborhood Hits	774	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

SPR2H_MOUSE
NC score	0.023894 (rank : 155)	θ value	4.03905 (rank : 122)
Query Neighborhood Hits	178	Target Neighborhood Hits	82	Shared Neighborhood Hits	7
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

SHAN2_MOUSE
NC score	0.023875 (rank : 156)	θ value	2.36792 (rank : 93)
Query Neighborhood Hits	178	Target Neighborhood Hits	446	Shared Neighborhood Hits	32
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

MAP2_HUMAN
NC score	0.023599 (rank : 157)	θ value	3.0926 (rank : 104)
Query Neighborhood Hits	178	Target Neighborhood Hits	348	Shared Neighborhood Hits	23
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

NSD1_MOUSE
NC score	0.022396 (rank : 158)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	178	Target Neighborhood Hits	472	Shared Neighborhood Hits	34
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

SFR14_MOUSE
NC score	0.022388 (rank : 159)	θ value	5.27518 (rank : 137)
Query Neighborhood Hits	178	Target Neighborhood Hits	238	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CH09, Q6PG19, Q80UY8, Q8BY32, Q8CFM0	Gene names	Sfrs14
Domain Architecture	No domain graphic available
Description	Putative splicing factor, arginine/serine-rich 14 (Arginine/serine- rich-splicing factor 14).

COIA1_MOUSE
NC score	0.021807 (rank : 160)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	178	Target Neighborhood Hits	481	Shared Neighborhood Hits	33
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

PCNT_MOUSE
NC score	0.021696 (rank : 161)	θ value	1.38821 (rank : 72)
Query Neighborhood Hits	178	Target Neighborhood Hits	1207	Shared Neighborhood Hits	27
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

K1949_HUMAN
NC score	0.021670 (rank : 162)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	178	Target Neighborhood Hits	121	Shared Neighborhood Hits	12
SwissProt Accessions	Q6NYC8, Q68CK8, Q6ZUJ6, Q8NDQ4, Q8TF52, Q9BRL9	Gene names	KIAA1949
Domain Architecture	No domain graphic available
Description	Protein KIAA1949.

LIGA_HUMAN
NC score	0.021402 (rank : 163)	θ value	2.36792 (rank : 88)
Query Neighborhood Hits	178	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	P41214, Q9NR27, Q9NSN0, Q9NV18, Q9NZ21	Gene names	LGTN, HCA56
Domain Architecture
Description	Ligatin (Hepatocellular carcinoma-associated antigen 56).

RHG09_HUMAN
NC score	0.021237 (rank : 164)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	178	Target Neighborhood Hits	186	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

B2L13_MOUSE
NC score	0.021032 (rank : 165)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	178	Target Neighborhood Hits	58	Shared Neighborhood Hits	9
SwissProt Accessions	P59017	Gene names	Bcl2l13, Mil1
Domain Architecture	No domain graphic available
Description	Bcl-2-like 13 protein (Protein Mil1) (Bcl-rambo).

ZC3H6_MOUSE
NC score	0.021006 (rank : 166)	θ value	1.06291 (rank : 68)
Query Neighborhood Hits	178	Target Neighborhood Hits	239	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

JPH2_MOUSE
NC score	0.020982 (rank : 167)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	178	Target Neighborhood Hits	279	Shared Neighborhood Hits	24
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

PHC3_HUMAN
NC score	0.020544 (rank : 168)	θ value	4.03905 (rank : 120)
Query Neighborhood Hits	178	Target Neighborhood Hits	218	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

ZN385_HUMAN
NC score	0.020436 (rank : 169)	θ value	6.88961 (rank : 155)
Query Neighborhood Hits	178	Target Neighborhood Hits	614	Shared Neighborhood Hits	35
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

SCUB3_MOUSE
NC score	0.020303 (rank : 170)	θ value	0.0736092 (rank : 40)
Query Neighborhood Hits	178	Target Neighborhood Hits	442	Shared Neighborhood Hits	6
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

HOOK2_HUMAN
NC score	0.020296 (rank : 171)	θ value	1.38821 (rank : 70)
Query Neighborhood Hits	178	Target Neighborhood Hits	714	Shared Neighborhood Hits	15
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

SCUB3_HUMAN
NC score	0.020097 (rank : 172)	θ value	0.0961366 (rank : 43)
Query Neighborhood Hits	178	Target Neighborhood Hits	428	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

K1688_HUMAN
NC score	0.019954 (rank : 173)	θ value	1.81305 (rank : 77)
Query Neighborhood Hits	178	Target Neighborhood Hits	217	Shared Neighborhood Hits	15
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

AIRE_MOUSE
NC score	0.019862 (rank : 174)	θ value	4.03905 (rank : 112)
Query Neighborhood Hits	178	Target Neighborhood Hits	196	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

DNL1_HUMAN
NC score	0.019858 (rank : 175)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	178	Target Neighborhood Hits	216	Shared Neighborhood Hits	23
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

DMN_HUMAN
NC score	0.019573 (rank : 176)	θ value	0.365318 (rank : 50)
Query Neighborhood Hits	178	Target Neighborhood Hits	690	Shared Neighborhood Hits	18
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

CUTL2_MOUSE
NC score	0.019236 (rank : 177)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	178	Target Neighborhood Hits	771	Shared Neighborhood Hits	38
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

TIF1G_HUMAN
NC score	0.018991 (rank : 178)	θ value	5.27518 (rank : 138)
Query Neighborhood Hits	178	Target Neighborhood Hits	410	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

MAST4_HUMAN
NC score	0.018747 (rank : 179)	θ value	0.0148317 (rank : 32)
Query Neighborhood Hits	178	Target Neighborhood Hits	1804	Shared Neighborhood Hits	68
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

IF4G3_MOUSE
NC score	0.017865 (rank : 180)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	178	Target Neighborhood Hits	279	Shared Neighborhood Hits	19
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

K0460_MOUSE
NC score	0.017753 (rank : 181)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	178	Target Neighborhood Hits	374	Shared Neighborhood Hits	24
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

TENS1_HUMAN
NC score	0.017670 (rank : 182)	θ value	8.99809 (rank : 177)
Query Neighborhood Hits	178	Target Neighborhood Hits	400	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

GA2L1_HUMAN
NC score	0.016807 (rank : 183)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	178	Target Neighborhood Hits	177	Shared Neighborhood Hits	19
SwissProt Accessions	Q99501, Q53EN7, Q92640, Q9BUY9	Gene names	GAS2L1, GAR22
Domain Architecture
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1) (GAS2-related protein on chromosome 22) (GAR22 protein).

MYLK_MOUSE
NC score	0.016693 (rank : 184)	θ value	0.00102713 (rank : 29)
Query Neighborhood Hits	178	Target Neighborhood Hits	1489	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

PRGC2_MOUSE
NC score	0.016492 (rank : 185)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	178	Target Neighborhood Hits	225	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

BOC_HUMAN
NC score	0.016316 (rank : 186)	θ value	1.38821 (rank : 69)
Query Neighborhood Hits	178	Target Neighborhood Hits	543	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

CUTL2_HUMAN
NC score	0.016059 (rank : 187)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	178	Target Neighborhood Hits	906	Shared Neighborhood Hits	36
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

ETV6_HUMAN
NC score	0.016048 (rank : 188)	θ value	2.36792 (rank : 86)
Query Neighborhood Hits	178	Target Neighborhood Hits	120	Shared Neighborhood Hits	10
SwissProt Accessions	P41212, Q9UMF6	Gene names	ETV6, TEL, TEL1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

SEZ6L_HUMAN
NC score	0.015867 (rank : 189)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	178	Target Neighborhood Hits	289	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

ANR11_HUMAN
NC score	0.015295 (rank : 190)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	178	Target Neighborhood Hits	1289	Shared Neighborhood Hits	49
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

NFAC1_MOUSE
NC score	0.015249 (rank : 191)	θ value	3.0926 (rank : 105)
Query Neighborhood Hits	178	Target Neighborhood Hits	92	Shared Neighborhood Hits	10
SwissProt Accessions	O88942, O70345	Gene names	Nfatc1, Nfat2, Nfatc
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

SOX17_MOUSE
NC score	0.015073 (rank : 192)	θ value	2.36792 (rank : 94)
Query Neighborhood Hits	178	Target Neighborhood Hits	223	Shared Neighborhood Hits	16
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

OBSCN_HUMAN
NC score	0.014825 (rank : 193)	θ value	0.365318 (rank : 52)
Query Neighborhood Hits	178	Target Neighborhood Hits	1931	Shared Neighborhood Hits	61
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

DYNA_MOUSE
NC score	0.014628 (rank : 194)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	178	Target Neighborhood Hits	1084	Shared Neighborhood Hits	36
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

EPN3_MOUSE
NC score	0.014543 (rank : 195)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	178	Target Neighborhood Hits	312	Shared Neighborhood Hits	31
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

NBEA_MOUSE
NC score	0.012917 (rank : 196)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	178	Target Neighborhood Hits	225	Shared Neighborhood Hits	13
SwissProt Accessions	Q9EPN1, Q8C931, Q9EPM9, Q9EPN0, Q9WVM9	Gene names	Nbea, Lyst2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2).

FBLN2_MOUSE
NC score	0.012826 (rank : 197)	θ value	1.81305 (rank : 76)
Query Neighborhood Hits	178	Target Neighborhood Hits	505	Shared Neighborhood Hits	28
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

U383_HUMAN
NC score	0.012420 (rank : 198)	θ value	6.88961 (rank : 154)
Query Neighborhood Hits	178	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IYL2	Gene names	C4orf23
Domain Architecture	No domain graphic available
Description	Putative methyltransferase UPF0383 (EC 2.1.1.-).

FRS3_HUMAN
NC score	0.012400 (rank : 199)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	178	Target Neighborhood Hits	76	Shared Neighborhood Hits	7
SwissProt Accessions	O43559, Q5T3D5	Gene names	FRS3
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (Suc1-associated neurotrophic factor target 2) (SNT-2) (FGFR signaling adaptor SNT2).

MYLK_HUMAN
NC score	0.012291 (rank : 200)	θ value	0.125558 (rank : 44)
Query Neighborhood Hits	178	Target Neighborhood Hits	1328	Shared Neighborhood Hits	19
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

CAN10_MOUSE
NC score	0.011738 (rank : 201)	θ value	1.81305 (rank : 75)
Query Neighborhood Hits	178	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ESK3, Q99J13, Q9WVF0	Gene names	Capn10, Capn8
Domain Architecture
Description	Calpain-10 (EC 3.4.22.-) (Calcium-activated neutral proteinase 10) (CANP 10).

CAC1A_HUMAN
NC score	0.011736 (rank : 202)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	178	Target Neighborhood Hits	387	Shared Neighborhood Hits	32
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

INVS_MOUSE
NC score	0.011680 (rank : 203)	θ value	1.38821 (rank : 71)
Query Neighborhood Hits	178	Target Neighborhood Hits	609	Shared Neighborhood Hits	39
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

CI114_HUMAN
NC score	0.011423 (rank : 204)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	178	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q5T280, Q6P469, Q6PGP9, Q6PIJ1, Q6PJV9	Gene names	C9orf114
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf114.

NFAC2_MOUSE
NC score	0.011307 (rank : 205)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	178	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q60591, Q60984, Q60985	Gene names	Nfatc2, Nfat1, Nfatp
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

LRIG1_HUMAN
NC score	0.010214 (rank : 206)	θ value	0.47712 (rank : 54)
Query Neighborhood Hits	178	Target Neighborhood Hits	654	Shared Neighborhood Hits	10
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

CQ028_HUMAN
NC score	0.010208 (rank : 207)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	178	Target Neighborhood Hits	56	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IV36, Q8N5L6, Q8TE83, Q9NT34	Gene names	C17orf28, DMC1
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 (Down-regulated in multiple cancers- 1).

B3A2_MOUSE
NC score	0.009767 (rank : 208)	θ value	2.36792 (rank : 83)
Query Neighborhood Hits	178	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	P13808, Q9ES09, Q9ES10, Q9ES11, Q9ES12, Q9ES13	Gene names	Slc4a2, Ae2
Domain Architecture
Description	Anion exchange protein 2 (Non-erythroid band 3-like protein) (AE2 anion exchanger) (Solute carrier family 4 member 2) (B3RP).

DDEF1_MOUSE
NC score	0.009681 (rank : 209)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	178	Target Neighborhood Hits	592	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

PAX2_HUMAN
NC score	0.009294 (rank : 210)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	178	Target Neighborhood Hits	84	Shared Neighborhood Hits	5
SwissProt Accessions	Q02962, Q15105, Q15110, Q15837	Gene names	PAX2
Domain Architecture
Description	Paired box protein Pax-2.

PAX2_MOUSE
NC score	0.009173 (rank : 211)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	178	Target Neighborhood Hits	86	Shared Neighborhood Hits	4
SwissProt Accessions	P32114	Gene names	Pax2, Pax-2
Domain Architecture
Description	Paired box protein Pax-2.

BRE1B_MOUSE
NC score	0.008923 (rank : 212)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	178	Target Neighborhood Hits	970	Shared Neighborhood Hits	20
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

FOG1_HUMAN
NC score	0.008108 (rank : 213)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	178	Target Neighborhood Hits	981	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

PCSK7_HUMAN
NC score	0.007783 (rank : 214)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	178	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q16549, Q9UL57	Gene names	PCSK7, LPC, PC7, PC8, SPC7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (PC8) (hPC8) (Lymphoma proprotein convertase).

GATA5_MOUSE
NC score	0.007589 (rank : 215)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	178	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	P97489	Gene names	Gata5
Domain Architecture
Description	Transcription factor GATA-5 (GATA-binding factor 5).

AATK_HUMAN
NC score	0.006778 (rank : 216)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	178	Target Neighborhood Hits	1243	Shared Neighborhood Hits	47
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

ESX1L_HUMAN
NC score	0.006696 (rank : 217)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	178	Target Neighborhood Hits	498	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

USH2A_MOUSE
NC score	0.006637 (rank : 218)	θ value	3.0926 (rank : 109)
Query Neighborhood Hits	178	Target Neighborhood Hits	626	Shared Neighborhood Hits	15
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

SPAG1_HUMAN
NC score	0.006338 (rank : 219)	θ value	8.99809 (rank : 174)
Query Neighborhood Hits	178	Target Neighborhood Hits	197	Shared Neighborhood Hits	6
SwissProt Accessions	Q07617, Q7Z5G1	Gene names	SPAG1
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (HSD-3.8).

PP16A_HUMAN
NC score	0.005320 (rank : 220)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	178	Target Neighborhood Hits	340	Shared Neighborhood Hits	7
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

PO6F1_MOUSE
NC score	0.005206 (rank : 221)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	178	Target Neighborhood Hits	581	Shared Neighborhood Hits	23
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

E41L2_MOUSE
NC score	0.005132 (rank : 222)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	178	Target Neighborhood Hits	459	Shared Neighborhood Hits	15
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

SCN9A_HUMAN
NC score	0.005063 (rank : 223)	θ value	6.88961 (rank : 151)
Query Neighborhood Hits	178	Target Neighborhood Hits	157	Shared Neighborhood Hits	6
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

ATBF1_HUMAN
NC score	0.004690 (rank : 224)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	178	Target Neighborhood Hits	1547	Shared Neighborhood Hits	43
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CHD1_HUMAN
NC score	0.004500 (rank : 225)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	178	Target Neighborhood Hits	337	Shared Neighborhood Hits	9
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

KIF9_HUMAN
NC score	0.004417 (rank : 226)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	178	Target Neighborhood Hits	118	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HAQ2, Q86Z28, Q9H8A4	Gene names	KIF9
Domain Architecture
Description	Kinesin-like protein KIF9.

PCDH9_HUMAN
NC score	0.004184 (rank : 227)	θ value	0.62314 (rank : 57)
Query Neighborhood Hits	178	Target Neighborhood Hits	180	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HC56	Gene names	PCDH9
Domain Architecture
Description	Protocadherin-9 precursor.

PLRG1_MOUSE
NC score	0.003892 (rank : 228)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	178	Target Neighborhood Hits	308	Shared Neighborhood Hits	2
SwissProt Accessions	Q922V4, O55039	Gene names	Plrg1
Domain Architecture
Description	Pleiotropic regulator 1.

ULK4_MOUSE
NC score	0.002847 (rank : 229)	θ value	5.27518 (rank : 139)
Query Neighborhood Hits	178	Target Neighborhood Hits	793	Shared Neighborhood Hits	7
SwissProt Accessions	Q3V129, Q2VP87, Q32LZ6, Q8BLS0, Q8C8Z5, Q9D4H6	Gene names	Ulk4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4).

FOXC2_HUMAN
NC score	0.002324 (rank : 230)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	178	Target Neighborhood Hits	236	Shared Neighborhood Hits	10
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

SEM5B_HUMAN
NC score	0.001960 (rank : 231)	θ value	5.27518 (rank : 136)
Query Neighborhood Hits	178	Target Neighborhood Hits	178	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

ZBTB4_HUMAN
NC score	0.001776 (rank : 232)	θ value	8.99809 (rank : 178)
Query Neighborhood Hits	178	Target Neighborhood Hits	926	Shared Neighborhood Hits	21
SwissProt Accessions	Q9P1Z0, Q7Z697, Q86XJ4, Q8N4V8	Gene names	ZBTB4, KIAA1538
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1).

ZN142_HUMAN
NC score	0.000113 (rank : 233)	θ value	3.0926 (rank : 111)
Query Neighborhood Hits	178	Target Neighborhood Hits	1007	Shared Neighborhood Hits	29
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).