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Network neighborhood for query Sequence : PKHA4_MOUSE

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PKHA4_MOUSE
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PKHA4_HUMAN
θ value	0 (rank : 1)	NC score	0.948125 (rank : 2)
Query Neighborhood Hits	202	Target Neighborhood Hits	283	Shared Neighborhood Hits	134
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA4_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	202	Target Neighborhood Hits	202	Shared Neighborhood Hits	202
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA5_HUMAN
θ value	9.52487e-34 (rank : 3)	NC score	0.660779 (rank : 5)
Query Neighborhood Hits	202	Target Neighborhood Hits	455	Shared Neighborhood Hits	104
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PKHA6_HUMAN
θ value	5.22648e-32 (rank : 4)	NC score	0.708256 (rank : 3)
Query Neighborhood Hits	202	Target Neighborhood Hits	556	Shared Neighborhood Hits	104
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
θ value	8.91499e-32 (rank : 5)	NC score	0.702313 (rank : 4)
Query Neighborhood Hits	202	Target Neighborhood Hits	591	Shared Neighborhood Hits	110
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

CNKR1_HUMAN
θ value	2.28291e-11 (rank : 6)	NC score	0.532983 (rank : 6)
Query Neighborhood Hits	202	Target Neighborhood Hits	154	Shared Neighborhood Hits	61
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CNKR2_HUMAN
θ value	2.61198e-07 (rank : 7)	NC score	0.441196 (rank : 7)
Query Neighborhood Hits	202	Target Neighborhood Hits	197	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	2.61198e-07 (rank : 8)	NC score	0.441076 (rank : 8)
Query Neighborhood Hits	202	Target Neighborhood Hits	197	Shared Neighborhood Hits	54
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

RHG25_MOUSE
θ value	2.61198e-07 (rank : 9)	NC score	0.289214 (rank : 23)
Query Neighborhood Hits	202	Target Neighborhood Hits	492	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_HUMAN
θ value	3.41135e-07 (rank : 10)	NC score	0.286715 (rank : 24)
Query Neighborhood Hits	202	Target Neighborhood Hits	550	Shared Neighborhood Hits	88
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CYH2_HUMAN
θ value	1.09739e-05 (rank : 11)	NC score	0.344893 (rank : 12)
Query Neighborhood Hits	202	Target Neighborhood Hits	175	Shared Neighborhood Hits	73
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
θ value	1.09739e-05 (rank : 12)	NC score	0.344684 (rank : 13)
Query Neighborhood Hits	202	Target Neighborhood Hits	171	Shared Neighborhood Hits	72
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH1_HUMAN
θ value	2.44474e-05 (rank : 13)	NC score	0.349389 (rank : 10)
Query Neighborhood Hits	202	Target Neighborhood Hits	184	Shared Neighborhood Hits	78
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH1_MOUSE
θ value	2.44474e-05 (rank : 14)	NC score	0.348747 (rank : 11)
Query Neighborhood Hits	202	Target Neighborhood Hits	176	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH3_HUMAN
θ value	2.44474e-05 (rank : 15)	NC score	0.350310 (rank : 9)
Query Neighborhood Hits	202	Target Neighborhood Hits	137	Shared Neighborhood Hits	71
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

MYO10_HUMAN
θ value	0.000121331 (rank : 16)	NC score	0.123949 (rank : 71)
Query Neighborhood Hits	202	Target Neighborhood Hits	920	Shared Neighborhood Hits	98
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

MRIP_MOUSE
θ value	0.00020696 (rank : 17)	NC score	0.246533 (rank : 26)
Query Neighborhood Hits	202	Target Neighborhood Hits	569	Shared Neighborhood Hits	85
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

FARP2_MOUSE
θ value	0.000270298 (rank : 18)	NC score	0.175194 (rank : 43)
Query Neighborhood Hits	202	Target Neighborhood Hits	209	Shared Neighborhood Hits	50
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

CYH3_MOUSE
θ value	0.000461057 (rank : 19)	NC score	0.340475 (rank : 15)
Query Neighborhood Hits	202	Target Neighborhood Hits	148	Shared Neighborhood Hits	72
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

CYH4_HUMAN
θ value	0.000461057 (rank : 20)	NC score	0.336442 (rank : 16)
Query Neighborhood Hits	202	Target Neighborhood Hits	135	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

CENB1_HUMAN
θ value	0.00102713 (rank : 21)	NC score	0.167980 (rank : 48)
Query Neighborhood Hits	202	Target Neighborhood Hits	383	Shared Neighborhood Hits	60
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CYH4_MOUSE
θ value	0.00102713 (rank : 22)	NC score	0.333063 (rank : 17)
Query Neighborhood Hits	202	Target Neighborhood Hits	134	Shared Neighborhood Hits	65
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

FARP2_HUMAN
θ value	0.00102713 (rank : 23)	NC score	0.170540 (rank : 45)
Query Neighborhood Hits	202	Target Neighborhood Hits	240	Shared Neighborhood Hits	50
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

IASPP_MOUSE
θ value	0.00175202 (rank : 24)	NC score	0.074514 (rank : 122)
Query Neighborhood Hits	202	Target Neighborhood Hits	1024	Shared Neighborhood Hits	48
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

PKHA1_HUMAN
θ value	0.00175202 (rank : 25)	NC score	0.344521 (rank : 14)
Query Neighborhood Hits	202	Target Neighborhood Hits	127	Shared Neighborhood Hits	63
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

3BP2_HUMAN
θ value	0.00228821 (rank : 26)	NC score	0.308497 (rank : 21)
Query Neighborhood Hits	202	Target Neighborhood Hits	296	Shared Neighborhood Hits	50
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

DGKH_HUMAN
θ value	0.00298849 (rank : 27)	NC score	0.169408 (rank : 46)
Query Neighborhood Hits	202	Target Neighborhood Hits	255	Shared Neighborhood Hits	56
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

MRIP_HUMAN
θ value	0.00298849 (rank : 28)	NC score	0.230856 (rank : 30)
Query Neighborhood Hits	202	Target Neighborhood Hits	578	Shared Neighborhood Hits	86
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

ANLN_HUMAN
θ value	0.00390308 (rank : 29)	NC score	0.232122 (rank : 29)
Query Neighborhood Hits	202	Target Neighborhood Hits	222	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

FGD5_HUMAN
θ value	0.00390308 (rank : 30)	NC score	0.199357 (rank : 37)
Query Neighborhood Hits	202	Target Neighborhood Hits	235	Shared Neighborhood Hits	41
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

TARA_MOUSE
θ value	0.00390308 (rank : 31)	NC score	0.199172 (rank : 38)
Query Neighborhood Hits	202	Target Neighborhood Hits	1133	Shared Neighborhood Hits	102
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

FGD5_MOUSE
θ value	0.00509761 (rank : 32)	NC score	0.203640 (rank : 34)
Query Neighborhood Hits	202	Target Neighborhood Hits	170	Shared Neighborhood Hits	38
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

3BP2_MOUSE
θ value	0.0113563 (rank : 33)	NC score	0.304326 (rank : 22)
Query Neighborhood Hits	202	Target Neighborhood Hits	142	Shared Neighborhood Hits	41
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

FARP1_HUMAN
θ value	0.0148317 (rank : 34)	NC score	0.169157 (rank : 47)
Query Neighborhood Hits	202	Target Neighborhood Hits	241	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FGD1_MOUSE
θ value	0.0148317 (rank : 35)	NC score	0.156541 (rank : 58)
Query Neighborhood Hits	202	Target Neighborhood Hits	387	Shared Neighborhood Hits	50
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

GNRP_MOUSE
θ value	0.0148317 (rank : 36)	NC score	0.160624 (rank : 54)
Query Neighborhood Hits	202	Target Neighborhood Hits	191	Shared Neighborhood Hits	52
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

CT151_HUMAN
θ value	0.0193708 (rank : 37)	NC score	0.099453 (rank : 103)
Query Neighborhood Hits	202	Target Neighborhood Hits	382	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

RIMB1_MOUSE
θ value	0.0193708 (rank : 38)	NC score	0.068581 (rank : 132)
Query Neighborhood Hits	202	Target Neighborhood Hits	1376	Shared Neighborhood Hits	58
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ANLN_MOUSE
θ value	0.0252991 (rank : 39)	NC score	0.198420 (rank : 39)
Query Neighborhood Hits	202	Target Neighborhood Hits	297	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

CENA1_HUMAN
θ value	0.0252991 (rank : 40)	NC score	0.164565 (rank : 52)
Query Neighborhood Hits	202	Target Neighborhood Hits	87	Shared Neighborhood Hits	44
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

FA47B_HUMAN
θ value	0.0252991 (rank : 41)	NC score	0.088475 (rank : 110)
Query Neighborhood Hits	202	Target Neighborhood Hits	431	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

FGD1_HUMAN
θ value	0.0252991 (rank : 42)	NC score	0.154671 (rank : 59)
Query Neighborhood Hits	202	Target Neighborhood Hits	367	Shared Neighborhood Hits	47
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

PKHA2_MOUSE
θ value	0.0252991 (rank : 43)	NC score	0.321597 (rank : 19)
Query Neighborhood Hits	202	Target Neighborhood Hits	116	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

CENB5_HUMAN
θ value	0.0330416 (rank : 44)	NC score	0.172689 (rank : 44)
Query Neighborhood Hits	202	Target Neighborhood Hits	395	Shared Neighborhood Hits	61
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CEND1_HUMAN
θ value	0.0330416 (rank : 45)	NC score	0.166705 (rank : 49)
Query Neighborhood Hits	202	Target Neighborhood Hits	284	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

CEND2_HUMAN
θ value	0.0330416 (rank : 46)	NC score	0.165340 (rank : 51)
Query Neighborhood Hits	202	Target Neighborhood Hits	166	Shared Neighborhood Hits	52
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

FGD6_MOUSE
θ value	0.0330416 (rank : 47)	NC score	0.180308 (rank : 41)
Query Neighborhood Hits	202	Target Neighborhood Hits	282	Shared Neighborhood Hits	50
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

CENB2_HUMAN
θ value	0.0431538 (rank : 48)	NC score	0.181759 (rank : 40)
Query Neighborhood Hits	202	Target Neighborhood Hits	425	Shared Neighborhood Hits	60
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

DOCK9_MOUSE
θ value	0.0431538 (rank : 49)	NC score	0.108952 (rank : 87)
Query Neighborhood Hits	202	Target Neighborhood Hits	79	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BIK4, Q921Y6	Gene names	Dock9, D14Wsu89e, Kiaa1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

OSBP1_HUMAN
θ value	0.0431538 (rank : 50)	NC score	0.151531 (rank : 62)
Query Neighborhood Hits	202	Target Neighborhood Hits	180	Shared Neighborhood Hits	50
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

PKHA2_HUMAN
θ value	0.0431538 (rank : 51)	NC score	0.310767 (rank : 20)
Query Neighborhood Hits	202	Target Neighborhood Hits	119	Shared Neighborhood Hits	66
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

EP300_HUMAN
θ value	0.0563607 (rank : 52)	NC score	0.057534 (rank : 159)
Query Neighborhood Hits	202	Target Neighborhood Hits	821	Shared Neighborhood Hits	50
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

MAGE1_HUMAN
θ value	0.0563607 (rank : 53)	NC score	0.049259 (rank : 197)
Query Neighborhood Hits	202	Target Neighborhood Hits	1389	Shared Neighborhood Hits	70
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

TARA_HUMAN
θ value	0.0563607 (rank : 54)	NC score	0.160794 (rank : 53)
Query Neighborhood Hits	202	Target Neighborhood Hits	1626	Shared Neighborhood Hits	118
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

GNRP_HUMAN
θ value	0.0736092 (rank : 55)	NC score	0.157877 (rank : 56)
Query Neighborhood Hits	202	Target Neighborhood Hits	239	Shared Neighborhood Hits	50
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

PCDA2_HUMAN
θ value	0.0736092 (rank : 56)	NC score	0.011473 (rank : 275)
Query Neighborhood Hits	202	Target Neighborhood Hits	192	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y5H9, O75287, Q9BTV3	Gene names	PCDHA2
Domain Architecture
Description	Protocadherin alpha 2 precursor (PCDH-alpha2).

SI1L3_HUMAN
θ value	0.0736092 (rank : 57)	NC score	0.054677 (rank : 173)
Query Neighborhood Hits	202	Target Neighborhood Hits	305	Shared Neighborhood Hits	28
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

PHLB1_HUMAN
θ value	0.0961366 (rank : 58)	NC score	0.132591 (rank : 66)
Query Neighborhood Hits	202	Target Neighborhood Hits	1038	Shared Neighborhood Hits	86
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

CEND1_MOUSE
θ value	0.125558 (rank : 59)	NC score	0.138394 (rank : 63)
Query Neighborhood Hits	202	Target Neighborhood Hits	260	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

DOCK9_HUMAN
θ value	0.125558 (rank : 60)	NC score	0.106346 (rank : 91)
Query Neighborhood Hits	202	Target Neighborhood Hits	82	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BZ29, Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26, Q9BZ27, Q9BZ28, Q9UPU4	Gene names	DOCK9, KIAA1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

GA2L2_MOUSE
θ value	0.125558 (rank : 61)	NC score	0.053412 (rank : 177)
Query Neighborhood Hits	202	Target Neighborhood Hits	395	Shared Neighborhood Hits	34
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

JADE2_MOUSE
θ value	0.125558 (rank : 62)	NC score	0.037984 (rank : 218)
Query Neighborhood Hits	202	Target Neighborhood Hits	560	Shared Neighborhood Hits	32
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

MTMRD_HUMAN
θ value	0.125558 (rank : 63)	NC score	0.101337 (rank : 98)
Query Neighborhood Hits	202	Target Neighborhood Hits	135	Shared Neighborhood Hits	44
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

PKHA1_MOUSE
θ value	0.163984 (rank : 64)	NC score	0.326054 (rank : 18)
Query Neighborhood Hits	202	Target Neighborhood Hits	120	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHB1_HUMAN
θ value	0.163984 (rank : 65)	NC score	0.235654 (rank : 28)
Query Neighborhood Hits	202	Target Neighborhood Hits	46	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UF11, Q9UBF5, Q9UI37, Q9UI44	Gene names	PLEKHB1, KPL1, PHR1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

PKHB2_MOUSE
θ value	0.163984 (rank : 66)	NC score	0.259790 (rank : 25)
Query Neighborhood Hits	202	Target Neighborhood Hits	48	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QZC7, Q3UDH6, Q8C4I4, Q8CA27	Gene names	Plekhb2, Evt2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

DGKD_HUMAN
θ value	0.21417 (rank : 67)	NC score	0.105112 (rank : 92)
Query Neighborhood Hits	202	Target Neighborhood Hits	231	Shared Neighborhood Hits	34
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

SPEG_MOUSE
θ value	0.21417 (rank : 68)	NC score	0.013996 (rank : 271)
Query Neighborhood Hits	202	Target Neighborhood Hits	1959	Shared Neighborhood Hits	66
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

CENA2_HUMAN
θ value	0.279714 (rank : 69)	NC score	0.132155 (rank : 67)
Query Neighborhood Hits	202	Target Neighborhood Hits	83	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

IASPP_HUMAN
θ value	0.279714 (rank : 70)	NC score	0.061599 (rank : 150)
Query Neighborhood Hits	202	Target Neighborhood Hits	688	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

OSBP2_MOUSE
θ value	0.279714 (rank : 71)	NC score	0.109662 (rank : 85)
Query Neighborhood Hits	202	Target Neighborhood Hits	150	Shared Neighborhood Hits	44
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

STXB4_HUMAN
θ value	0.279714 (rank : 72)	NC score	0.048958 (rank : 199)
Query Neighborhood Hits	202	Target Neighborhood Hits	616	Shared Neighborhood Hits	33
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

ZNHI4_MOUSE
θ value	0.279714 (rank : 73)	NC score	0.068532 (rank : 133)
Query Neighborhood Hits	202	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	Q99PT3, Q9CY38	Gene names	Znhit4, Hmga1l4, Papa1
Domain Architecture	No domain graphic available
Description	Zinc finger HIT domain-containing protein 4 (PAP-1-associated protein 1) (PAPA-1) (High mobility group AT-hook 1-like 4).

ANK2_HUMAN
θ value	0.365318 (rank : 74)	NC score	0.038940 (rank : 216)
Query Neighborhood Hits	202	Target Neighborhood Hits	1615	Shared Neighborhood Hits	71
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

GOGA5_MOUSE
θ value	0.365318 (rank : 75)	NC score	0.057464 (rank : 161)
Query Neighborhood Hits	202	Target Neighborhood Hits	1434	Shared Neighborhood Hits	66
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

LIPA2_MOUSE
θ value	0.365318 (rank : 76)	NC score	0.051175 (rank : 188)
Query Neighborhood Hits	202	Target Neighborhood Hits	1282	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

MLL3_HUMAN
θ value	0.365318 (rank : 77)	NC score	0.042864 (rank : 209)
Query Neighborhood Hits	202	Target Neighborhood Hits	1644	Shared Neighborhood Hits	64
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PKHB2_HUMAN
θ value	0.365318 (rank : 78)	NC score	0.243989 (rank : 27)
Query Neighborhood Hits	202	Target Neighborhood Hits	54	Shared Neighborhood Hits	39
SwissProt Accessions	Q96CS7, Q86W37, Q9BV75, Q9NWK1	Gene names	PLEKHB2, EVT2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

SC24C_HUMAN
θ value	0.365318 (rank : 79)	NC score	0.052988 (rank : 178)
Query Neighborhood Hits	202	Target Neighborhood Hits	662	Shared Neighborhood Hits	32
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

TRI39_HUMAN
θ value	0.365318 (rank : 80)	NC score	0.017963 (rank : 266)
Query Neighborhood Hits	202	Target Neighborhood Hits	693	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

DIDO1_HUMAN
θ value	0.47712 (rank : 81)	NC score	0.070934 (rank : 129)
Query Neighborhood Hits	202	Target Neighborhood Hits	960	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

GAB2_HUMAN
θ value	0.47712 (rank : 82)	NC score	0.156691 (rank : 57)
Query Neighborhood Hits	202	Target Neighborhood Hits	188	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

LMO7_HUMAN
θ value	0.47712 (rank : 83)	NC score	0.054430 (rank : 175)
Query Neighborhood Hits	202	Target Neighborhood Hits	507	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

NCOA6_HUMAN
θ value	0.47712 (rank : 84)	NC score	0.068269 (rank : 135)
Query Neighborhood Hits	202	Target Neighborhood Hits	1202	Shared Neighborhood Hits	67
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PKHB1_MOUSE
θ value	0.47712 (rank : 85)	NC score	0.216593 (rank : 32)
Query Neighborhood Hits	202	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QYE9, Q9QYB3, Q9QYB4, Q9QYD2, Q9QYD3	Gene names	Plekhb1, Phr1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

CROCC_HUMAN
θ value	0.62314 (rank : 86)	NC score	0.057172 (rank : 162)
Query Neighborhood Hits	202	Target Neighborhood Hits	1409	Shared Neighborhood Hits	67
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

FGD6_HUMAN
θ value	0.62314 (rank : 87)	NC score	0.166600 (rank : 50)
Query Neighborhood Hits	202	Target Neighborhood Hits	237	Shared Neighborhood Hits	44
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

LIPA1_HUMAN
θ value	0.62314 (rank : 88)	NC score	0.044070 (rank : 203)
Query Neighborhood Hits	202	Target Neighborhood Hits	1294	Shared Neighborhood Hits	53
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

RIMB1_HUMAN
θ value	0.62314 (rank : 89)	NC score	0.071585 (rank : 126)
Query Neighborhood Hits	202	Target Neighborhood Hits	1479	Shared Neighborhood Hits	66
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

CI079_HUMAN
θ value	0.813845 (rank : 90)	NC score	0.052541 (rank : 182)
Query Neighborhood Hits	202	Target Neighborhood Hits	288	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

CRTC1_HUMAN
θ value	0.813845 (rank : 91)	NC score	0.050432 (rank : 192)
Query Neighborhood Hits	202	Target Neighborhood Hits	319	Shared Neighborhood Hits	27
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

LAMA3_MOUSE
θ value	0.813845 (rank : 92)	NC score	0.019365 (rank : 262)
Query Neighborhood Hits	202	Target Neighborhood Hits	859	Shared Neighborhood Hits	25
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

SF3B1_HUMAN
θ value	0.813845 (rank : 93)	NC score	0.063509 (rank : 146)
Query Neighborhood Hits	202	Target Neighborhood Hits	341	Shared Neighborhood Hits	28
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	0.813845 (rank : 94)	NC score	0.063403 (rank : 147)
Query Neighborhood Hits	202	Target Neighborhood Hits	352	Shared Neighborhood Hits	27
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

USF2_HUMAN
θ value	0.813845 (rank : 95)	NC score	0.042255 (rank : 211)
Query Neighborhood Hits	202	Target Neighborhood Hits	155	Shared Neighborhood Hits	5
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF2_MOUSE
θ value	0.813845 (rank : 96)	NC score	0.043463 (rank : 206)
Query Neighborhood Hits	202	Target Neighborhood Hits	173	Shared Neighborhood Hits	7
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

OSBP2_HUMAN
θ value	1.06291 (rank : 97)	NC score	0.117438 (rank : 79)
Query Neighborhood Hits	202	Target Neighborhood Hits	154	Shared Neighborhood Hits	49
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

SON_HUMAN
θ value	1.06291 (rank : 98)	NC score	0.046243 (rank : 201)
Query Neighborhood Hits	202	Target Neighborhood Hits	1568	Shared Neighborhood Hits	70
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

DYN2_HUMAN
θ value	1.38821 (rank : 99)	NC score	0.100218 (rank : 100)
Query Neighborhood Hits	202	Target Neighborhood Hits	112	Shared Neighborhood Hits	43
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

DYN2_MOUSE
θ value	1.38821 (rank : 100)	NC score	0.099552 (rank : 102)
Query Neighborhood Hits	202	Target Neighborhood Hits	104	Shared Neighborhood Hits	40
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

FA13C_MOUSE
θ value	1.38821 (rank : 101)	NC score	0.025585 (rank : 246)
Query Neighborhood Hits	202	Target Neighborhood Hits	79	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

FOXE2_HUMAN
θ value	1.38821 (rank : 102)	NC score	0.013307 (rank : 272)
Query Neighborhood Hits	202	Target Neighborhood Hits	236	Shared Neighborhood Hits	13
SwissProt Accessions	Q99526	Gene names	FOXE2
Domain Architecture
Description	Forkhead box protein E2 (HNF-3/fork head-like protein 5) (HFKL5) (HFKH4).

GAB2_MOUSE
θ value	1.38821 (rank : 103)	NC score	0.152442 (rank : 61)
Query Neighborhood Hits	202	Target Neighborhood Hits	220	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

KCNQ5_HUMAN
θ value	1.38821 (rank : 104)	NC score	0.020675 (rank : 260)
Query Neighborhood Hits	202	Target Neighborhood Hits	163	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

LAMA3_HUMAN
θ value	1.38821 (rank : 105)	NC score	0.025200 (rank : 247)
Query Neighborhood Hits	202	Target Neighborhood Hits	760	Shared Neighborhood Hits	30
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

MYO15_HUMAN
θ value	1.38821 (rank : 106)	NC score	0.037447 (rank : 219)
Query Neighborhood Hits	202	Target Neighborhood Hits	671	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NIPA_MOUSE
θ value	1.38821 (rank : 107)	NC score	0.031801 (rank : 234)
Query Neighborhood Hits	202	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q80YV2, Q3TJE6, Q80Z11, Q8BTW5, Q8CI56, Q8R3U7	Gene names	Zc3hc1, Nipa
Domain Architecture	No domain graphic available
Description	Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (mNIPA) (Zinc finger C3HC-type protein 1).

PHLPP_MOUSE
θ value	1.38821 (rank : 108)	NC score	0.024513 (rank : 250)
Query Neighborhood Hits	202	Target Neighborhood Hits	394	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

PTPR2_MOUSE
θ value	1.38821 (rank : 109)	NC score	0.022560 (rank : 256)
Query Neighborhood Hits	202	Target Neighborhood Hits	120	Shared Neighborhood Hits	3
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

RTN2_HUMAN
θ value	1.38821 (rank : 110)	NC score	0.026217 (rank : 245)
Query Neighborhood Hits	202	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	O75298, O60509, Q7RTM6, Q7RTN1, Q7RTN2	Gene names	RTN2, NSPL1
Domain Architecture
Description	Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (NSPLI).

TRI39_MOUSE
θ value	1.38821 (rank : 111)	NC score	0.016164 (rank : 268)
Query Neighborhood Hits	202	Target Neighborhood Hits	691	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

CAPS2_MOUSE
θ value	1.81305 (rank : 112)	NC score	0.084329 (rank : 111)
Query Neighborhood Hits	202	Target Neighborhood Hits	78	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BYR5, O08903, Q66JM7, Q6PCL7, Q76I88, Q7TMM6, Q80ZV8, Q8BL25, Q8BY04, Q8K3K6	Gene names	Cadps2, Caps2
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2).

DAPP1_MOUSE
θ value	1.81305 (rank : 113)	NC score	0.208651 (rank : 33)
Query Neighborhood Hits	202	Target Neighborhood Hits	225	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

GLE1_HUMAN
θ value	1.81305 (rank : 114)	NC score	0.043439 (rank : 207)
Query Neighborhood Hits	202	Target Neighborhood Hits	445	Shared Neighborhood Hits	27
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

K1219_HUMAN
θ value	1.81305 (rank : 115)	NC score	0.035498 (rank : 225)
Query Neighborhood Hits	202	Target Neighborhood Hits	85	Shared Neighborhood Hits	6
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

K1C16_HUMAN
θ value	1.81305 (rank : 116)	NC score	0.024614 (rank : 249)
Query Neighborhood Hits	202	Target Neighborhood Hits	440	Shared Neighborhood Hits	33
SwissProt Accessions	P08779, P30654, Q16402, Q9UBG8	Gene names	KRT16, KRT16A
Domain Architecture
Description	Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16).

TPR_HUMAN
θ value	1.81305 (rank : 117)	NC score	0.043839 (rank : 204)
Query Neighborhood Hits	202	Target Neighborhood Hits	1921	Shared Neighborhood Hits	78
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

ATX2_MOUSE
θ value	2.36792 (rank : 118)	NC score	0.037177 (rank : 220)
Query Neighborhood Hits	202	Target Neighborhood Hits	445	Shared Neighborhood Hits	32
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

CENPF_HUMAN
θ value	2.36792 (rank : 119)	NC score	0.041551 (rank : 213)
Query Neighborhood Hits	202	Target Neighborhood Hits	1932	Shared Neighborhood Hits	69
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

FHOD1_HUMAN
θ value	2.36792 (rank : 120)	NC score	0.023450 (rank : 253)
Query Neighborhood Hits	202	Target Neighborhood Hits	184	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

MRCKB_MOUSE
θ value	2.36792 (rank : 121)	NC score	0.015735 (rank : 269)
Query Neighborhood Hits	202	Target Neighborhood Hits	2180	Shared Neighborhood Hits	63
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

PCNT_HUMAN
θ value	2.36792 (rank : 122)	NC score	0.048606 (rank : 200)
Query Neighborhood Hits	202	Target Neighborhood Hits	1551	Shared Neighborhood Hits	68
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

PHLB1_MOUSE
θ value	2.36792 (rank : 123)	NC score	0.135977 (rank : 65)
Query Neighborhood Hits	202	Target Neighborhood Hits	678	Shared Neighborhood Hits	82
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PHLPP_HUMAN
θ value	2.36792 (rank : 124)	NC score	0.024371 (rank : 252)
Query Neighborhood Hits	202	Target Neighborhood Hits	604	Shared Neighborhood Hits	31
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

SFPQ_HUMAN
θ value	2.36792 (rank : 125)	NC score	0.055272 (rank : 170)
Query Neighborhood Hits	202	Target Neighborhood Hits	986	Shared Neighborhood Hits	63
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SNPC4_HUMAN
θ value	2.36792 (rank : 126)	NC score	0.042914 (rank : 208)
Query Neighborhood Hits	202	Target Neighborhood Hits	589	Shared Neighborhood Hits	40
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

CAPS1_HUMAN
θ value	3.0926 (rank : 127)	NC score	0.078831 (rank : 119)
Query Neighborhood Hits	202	Target Neighborhood Hits	86	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ULU8, Q13339, Q6GQQ6, Q8N2Z5, Q8N3M7, Q8NFR0, Q96BC2	Gene names	CADPS, CAPS, CAPS1, KIAA1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

CAPS1_MOUSE
θ value	3.0926 (rank : 128)	NC score	0.079348 (rank : 118)
Query Neighborhood Hits	202	Target Neighborhood Hits	93	Shared Neighborhood Hits	24
SwissProt Accessions	Q80TJ1, Q3TSP2, Q61374, Q6AXB4, Q6PGF0	Gene names	Cadps, Caps, Caps1, Kiaa1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

CAPS2_HUMAN
θ value	3.0926 (rank : 129)	NC score	0.077937 (rank : 120)
Query Neighborhood Hits	202	Target Neighborhood Hits	81	Shared Neighborhood Hits	29
SwissProt Accessions	Q86UW7, Q658Q2, Q7Z5T7, Q8IZW9, Q8N7M4, Q9H6P4, Q9HCI1, Q9NWK8	Gene names	CADPS2, CAPS2, KIAA1591
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2).

CP250_MOUSE
θ value	3.0926 (rank : 130)	NC score	0.045939 (rank : 202)
Query Neighborhood Hits	202	Target Neighborhood Hits	1583	Shared Neighborhood Hits	65
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

DAPP1_HUMAN
θ value	3.0926 (rank : 131)	NC score	0.202502 (rank : 35)
Query Neighborhood Hits	202	Target Neighborhood Hits	227	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DNMT1_HUMAN
θ value	3.0926 (rank : 132)	NC score	0.028534 (rank : 241)
Query Neighborhood Hits	202	Target Neighborhood Hits	401	Shared Neighborhood Hits	24
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

DOC10_HUMAN
θ value	3.0926 (rank : 133)	NC score	0.095333 (rank : 106)
Query Neighborhood Hits	202	Target Neighborhood Hits	88	Shared Neighborhood Hits	23
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).

GOGA5_HUMAN
θ value	3.0926 (rank : 134)	NC score	0.049062 (rank : 198)
Query Neighborhood Hits	202	Target Neighborhood Hits	1168	Shared Neighborhood Hits	58
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

HIF1A_MOUSE
θ value	3.0926 (rank : 135)	NC score	0.009761 (rank : 277)
Query Neighborhood Hits	202	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8	Gene names	Hif1a
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).

IWS1_MOUSE
θ value	3.0926 (rank : 136)	NC score	0.031237 (rank : 235)
Query Neighborhood Hits	202	Target Neighborhood Hits	1258	Shared Neighborhood Hits	49
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

K1C12_MOUSE
θ value	3.0926 (rank : 137)	NC score	0.016356 (rank : 267)
Query Neighborhood Hits	202	Target Neighborhood Hits	409	Shared Neighborhood Hits	22
SwissProt Accessions	Q64291	Gene names	Krt12, Krt1-12, Krt1.12
Domain Architecture
Description	Keratin, type I cytoskeletal 12 (Cytokeratin-12) (CK-12) (Keratin-12) (K12).

AIM1_HUMAN
θ value	4.03905 (rank : 138)	NC score	0.026645 (rank : 243)
Query Neighborhood Hits	202	Target Neighborhood Hits	247	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

CCD96_HUMAN
θ value	4.03905 (rank : 139)	NC score	0.033007 (rank : 227)
Query Neighborhood Hits	202	Target Neighborhood Hits	595	Shared Neighborhood Hits	43
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

HXA3_MOUSE
θ value	4.03905 (rank : 140)	NC score	0.006181 (rank : 280)
Query Neighborhood Hits	202	Target Neighborhood Hits	558	Shared Neighborhood Hits	25
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

K1219_MOUSE
θ value	4.03905 (rank : 141)	NC score	0.032032 (rank : 232)
Query Neighborhood Hits	202	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BQZ4, Q80TH5, Q8BQN1	Gene names	Kiaa1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

KCNQ1_MOUSE
θ value	4.03905 (rank : 142)	NC score	0.018150 (rank : 265)
Query Neighborhood Hits	202	Target Neighborhood Hits	175	Shared Neighborhood Hits	11
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ4_HUMAN
θ value	4.03905 (rank : 143)	NC score	0.024376 (rank : 251)
Query Neighborhood Hits	202	Target Neighborhood Hits	136	Shared Neighborhood Hits	7
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

MAGL2_HUMAN
θ value	4.03905 (rank : 144)	NC score	0.015718 (rank : 270)
Query Neighborhood Hits	202	Target Neighborhood Hits	69	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UJ55	Gene names	MAGEL2, NDNL1
Domain Architecture
Description	MAGE-like protein 2 (Necdin-like protein 1) (Protein nM15).

NPBL_MOUSE
θ value	4.03905 (rank : 145)	NC score	0.051226 (rank : 187)
Query Neighborhood Hits	202	Target Neighborhood Hits	1041	Shared Neighborhood Hits	42
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PERI_HUMAN
θ value	4.03905 (rank : 146)	NC score	0.020876 (rank : 258)
Query Neighborhood Hits	202	Target Neighborhood Hits	506	Shared Neighborhood Hits	34
SwissProt Accessions	P41219, Q8N577	Gene names	PRPH
Domain Architecture
Description	Peripherin.

PERI_MOUSE
θ value	4.03905 (rank : 147)	NC score	0.022218 (rank : 257)
Query Neighborhood Hits	202	Target Neighborhood Hits	502	Shared Neighborhood Hits	34
SwissProt Accessions	P15331, O35688, O35689	Gene names	Prph, Prph1
Domain Architecture
Description	Peripherin.

PHLB2_MOUSE
θ value	4.03905 (rank : 148)	NC score	0.101667 (rank : 96)
Query Neighborhood Hits	202	Target Neighborhood Hits	1016	Shared Neighborhood Hits	74
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PLEK_HUMAN
θ value	4.03905 (rank : 149)	NC score	0.229429 (rank : 31)
Query Neighborhood Hits	202	Target Neighborhood Hits	110	Shared Neighborhood Hits	59
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PRP2_MOUSE
θ value	4.03905 (rank : 150)	NC score	0.082977 (rank : 112)
Query Neighborhood Hits	202	Target Neighborhood Hits	347	Shared Neighborhood Hits	42
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

SELPL_MOUSE
θ value	4.03905 (rank : 151)	NC score	0.033239 (rank : 226)
Query Neighborhood Hits	202	Target Neighborhood Hits	588	Shared Neighborhood Hits	37
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SYN1_HUMAN
θ value	4.03905 (rank : 152)	NC score	0.052927 (rank : 179)
Query Neighborhood Hits	202	Target Neighborhood Hits	419	Shared Neighborhood Hits	50
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

T22D4_HUMAN
θ value	4.03905 (rank : 153)	NC score	0.036255 (rank : 222)
Query Neighborhood Hits	202	Target Neighborhood Hits	403	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

TBCD1_HUMAN
θ value	4.03905 (rank : 154)	NC score	0.020297 (rank : 261)
Query Neighborhood Hits	202	Target Neighborhood Hits	276	Shared Neighborhood Hits	17
SwissProt Accessions	Q86TI0, Q96K82, Q9UPP4	Gene names	TBC1D1, KIAA1108
Domain Architecture
Description	TBC1 domain family member 1.

TBCD2_HUMAN
θ value	4.03905 (rank : 155)	NC score	0.081453 (rank : 114)
Query Neighborhood Hits	202	Target Neighborhood Hits	419	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

UBP42_HUMAN
θ value	4.03905 (rank : 156)	NC score	0.020730 (rank : 259)
Query Neighborhood Hits	202	Target Neighborhood Hits	445	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

C43BP_HUMAN
θ value	5.27518 (rank : 157)	NC score	0.127346 (rank : 70)
Query Neighborhood Hits	202	Target Neighborhood Hits	87	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

CJ012_HUMAN
θ value	5.27518 (rank : 158)	NC score	0.024716 (rank : 248)
Query Neighborhood Hits	202	Target Neighborhood Hits	467	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

EP15R_MOUSE
θ value	5.27518 (rank : 159)	NC score	0.035499 (rank : 224)
Query Neighborhood Hits	202	Target Neighborhood Hits	1135	Shared Neighborhood Hits	54
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

IL17B_HUMAN
θ value	5.27518 (rank : 160)	NC score	0.019070 (rank : 263)
Query Neighborhood Hits	202	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UHF5	Gene names	IL17B, IL20, NIRF, ZCYTO7
Domain Architecture
Description	Interleukin-17B precursor (IL-17B) (Cytokine-like protein Zcyto7) (Neuronal interleukin-17-related factor) (Interleukin-20) (IL-20).

MINT_MOUSE
θ value	5.27518 (rank : 161)	NC score	0.032617 (rank : 229)
Query Neighborhood Hits	202	Target Neighborhood Hits	1514	Shared Neighborhood Hits	65
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NFH_MOUSE
θ value	5.27518 (rank : 162)	NC score	0.052922 (rank : 180)
Query Neighborhood Hits	202	Target Neighborhood Hits	2247	Shared Neighborhood Hits	100
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NHS_HUMAN
θ value	5.27518 (rank : 163)	NC score	0.027417 (rank : 242)
Query Neighborhood Hits	202	Target Neighborhood Hits	198	Shared Neighborhood Hits	14
SwissProt Accessions	Q6T4R5, Q5J7Q0, Q5J7Q1, Q68DR5	Gene names	NHS
Domain Architecture	No domain graphic available
Description	Nance-Horan syndrome protein (Congenital cataracts and dental anomalies protein).

NPFF2_HUMAN
θ value	5.27518 (rank : 164)	NC score	-0.003437 (rank : 286)
Query Neighborhood Hits	202	Target Neighborhood Hits	804	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5X5, Q96RV1, Q9NR49	Gene names	NPFFR2, GPR74, NPFF2, NPGPR
Domain Architecture
Description	Neuropeptide FF receptor 2 (Neuropeptide G-protein coupled receptor) (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77).

PHLB2_HUMAN
θ value	5.27518 (rank : 165)	NC score	0.100113 (rank : 101)
Query Neighborhood Hits	202	Target Neighborhood Hits	964	Shared Neighborhood Hits	69
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

RP3A_MOUSE
θ value	5.27518 (rank : 166)	NC score	0.018847 (rank : 264)
Query Neighborhood Hits	202	Target Neighborhood Hits	510	Shared Neighborhood Hits	35
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SI1L2_MOUSE
θ value	5.27518 (rank : 167)	NC score	0.023332 (rank : 254)
Query Neighborhood Hits	202	Target Neighborhood Hits	124	Shared Neighborhood Hits	7
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SPTN2_HUMAN
θ value	5.27518 (rank : 168)	NC score	0.030234 (rank : 237)
Query Neighborhood Hits	202	Target Neighborhood Hits	535	Shared Neighborhood Hits	42
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

SYN1_MOUSE
θ value	5.27518 (rank : 169)	NC score	0.043629 (rank : 205)
Query Neighborhood Hits	202	Target Neighborhood Hits	363	Shared Neighborhood Hits	39
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

ULK1_HUMAN
θ value	5.27518 (rank : 170)	NC score	0.001563 (rank : 284)
Query Neighborhood Hits	202	Target Neighborhood Hits	1121	Shared Neighborhood Hits	30
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

ZN409_HUMAN
θ value	5.27518 (rank : 171)	NC score	0.007118 (rank : 279)
Query Neighborhood Hits	202	Target Neighborhood Hits	842	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

C43BP_MOUSE
θ value	6.88961 (rank : 172)	NC score	0.130372 (rank : 68)
Query Neighborhood Hits	202	Target Neighborhood Hits	91	Shared Neighborhood Hits	47
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

CIC_HUMAN
θ value	6.88961 (rank : 173)	NC score	0.026563 (rank : 244)
Query Neighborhood Hits	202	Target Neighborhood Hits	992	Shared Neighborhood Hits	56
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CING_MOUSE
θ value	6.88961 (rank : 174)	NC score	0.040314 (rank : 215)
Query Neighborhood Hits	202	Target Neighborhood Hits	1432	Shared Neighborhood Hits	55
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CUTL2_MOUSE
θ value	6.88961 (rank : 175)	NC score	0.031002 (rank : 236)
Query Neighborhood Hits	202	Target Neighborhood Hits	771	Shared Neighborhood Hits	47
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

GAB1_MOUSE
θ value	6.88961 (rank : 176)	NC score	0.121147 (rank : 74)
Query Neighborhood Hits	202	Target Neighborhood Hits	233	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GOGA4_MOUSE
θ value	6.88961 (rank : 177)	NC score	0.038597 (rank : 217)
Query Neighborhood Hits	202	Target Neighborhood Hits	1939	Shared Neighborhood Hits	65
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

GRIN1_MOUSE
θ value	6.88961 (rank : 178)	NC score	0.032243 (rank : 230)
Query Neighborhood Hits	202	Target Neighborhood Hits	337	Shared Neighborhood Hits	30
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

HCN1_HUMAN
θ value	6.88961 (rank : 179)	NC score	0.005892 (rank : 281)
Query Neighborhood Hits	202	Target Neighborhood Hits	120	Shared Neighborhood Hits	9
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

MYO9B_HUMAN
θ value	6.88961 (rank : 180)	NC score	0.036811 (rank : 221)
Query Neighborhood Hits	202	Target Neighborhood Hits	641	Shared Neighborhood Hits	37
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

PJA1_HUMAN
θ value	6.88961 (rank : 181)	NC score	0.012682 (rank : 273)
Query Neighborhood Hits	202	Target Neighborhood Hits	159	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

RASA2_MOUSE
θ value	6.88961 (rank : 182)	NC score	0.068051 (rank : 136)
Query Neighborhood Hits	202	Target Neighborhood Hits	159	Shared Neighborhood Hits	35
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RPKL1_HUMAN
θ value	6.88961 (rank : 183)	NC score	0.002028 (rank : 283)
Query Neighborhood Hits	202	Target Neighborhood Hits	708	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6S9, Q69YT9, Q6ZMQ6, Q96NR9, Q9BSU9	Gene names	RPS6KL1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

TTF2_MOUSE
θ value	6.88961 (rank : 184)	NC score	0.010421 (rank : 276)
Query Neighborhood Hits	202	Target Neighborhood Hits	364	Shared Neighborhood Hits	13
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

ULK1_MOUSE
θ value	6.88961 (rank : 185)	NC score	0.000489 (rank : 285)
Query Neighborhood Hits	202	Target Neighborhood Hits	1214	Shared Neighborhood Hits	34
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

WNK2_HUMAN
θ value	6.88961 (rank : 186)	NC score	0.005876 (rank : 282)
Query Neighborhood Hits	202	Target Neighborhood Hits	1407	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ZNHI4_HUMAN
θ value	6.88961 (rank : 187)	NC score	0.040492 (rank : 214)
Query Neighborhood Hits	202	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q9C086	Gene names	ZNHIT4, HMGA1L4, PAPA1
Domain Architecture	No domain graphic available
Description	Zinc finger HIT domain-containing protein 4 (PAP-1-associated protein 1) (PAPA-1) (High mobility group AT-hook 1-like 4).

ANR15_HUMAN
θ value	8.99809 (rank : 188)	NC score	0.029556 (rank : 239)
Query Neighborhood Hits	202	Target Neighborhood Hits	478	Shared Neighborhood Hits	25
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

BAZ2B_HUMAN
θ value	8.99809 (rank : 189)	NC score	0.029057 (rank : 240)
Query Neighborhood Hits	202	Target Neighborhood Hits	803	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BSN_MOUSE
θ value	8.99809 (rank : 190)	NC score	0.056227 (rank : 165)
Query Neighborhood Hits	202	Target Neighborhood Hits	2057	Shared Neighborhood Hits	99
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

GTSE1_MOUSE
θ value	8.99809 (rank : 191)	NC score	0.031942 (rank : 233)
Query Neighborhood Hits	202	Target Neighborhood Hits	245	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

HIP1_HUMAN
θ value	8.99809 (rank : 192)	NC score	0.032059 (rank : 231)
Query Neighborhood Hits	202	Target Neighborhood Hits	1016	Shared Neighborhood Hits	45
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

IF4G1_HUMAN
θ value	8.99809 (rank : 193)	NC score	0.023331 (rank : 255)
Query Neighborhood Hits	202	Target Neighborhood Hits	347	Shared Neighborhood Hits	32
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

LIPB1_HUMAN
θ value	8.99809 (rank : 194)	NC score	0.029827 (rank : 238)
Query Neighborhood Hits	202	Target Neighborhood Hits	640	Shared Neighborhood Hits	36
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

PSL1_HUMAN
θ value	8.99809 (rank : 195)	NC score	0.035499 (rank : 223)
Query Neighborhood Hits	202	Target Neighborhood Hits	650	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RHG09_HUMAN
θ value	8.99809 (rank : 196)	NC score	0.041647 (rank : 212)
Query Neighborhood Hits	202	Target Neighborhood Hits	186	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

SAPS1_HUMAN
θ value	8.99809 (rank : 197)	NC score	0.042511 (rank : 210)
Query Neighborhood Hits	202	Target Neighborhood Hits	704	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

STAT6_HUMAN
θ value	8.99809 (rank : 198)	NC score	0.011987 (rank : 274)
Query Neighborhood Hits	202	Target Neighborhood Hits	132	Shared Neighborhood Hits	7
SwissProt Accessions	P42226	Gene names	STAT6
Domain Architecture
Description	Signal transducer and activator of transcription 6 (IL-4 Stat).

TIAM1_HUMAN
θ value	8.99809 (rank : 199)	NC score	0.059723 (rank : 154)
Query Neighborhood Hits	202	Target Neighborhood Hits	225	Shared Neighborhood Hits	30
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TIAM1_MOUSE
θ value	8.99809 (rank : 200)	NC score	0.054782 (rank : 171)
Query Neighborhood Hits	202	Target Neighborhood Hits	205	Shared Neighborhood Hits	25
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TSC1_HUMAN
θ value	8.99809 (rank : 201)	NC score	0.032866 (rank : 228)
Query Neighborhood Hits	202	Target Neighborhood Hits	765	Shared Neighborhood Hits	37
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

ZAN_MOUSE
θ value	8.99809 (rank : 202)	NC score	0.007141 (rank : 278)
Query Neighborhood Hits	202	Target Neighborhood Hits	808	Shared Neighborhood Hits	15
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ABR_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.070976 (rank : 128)
Query Neighborhood Hits	202	Target Neighborhood Hits	166	Shared Neighborhood Hits	21
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

ALEX_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.059384 (rank : 155)
Query Neighborhood Hits	202	Target Neighborhood Hits	361	Shared Neighborhood Hits	35
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ARHGF_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.051850 (rank : 183)
Query Neighborhood Hits	202	Target Neighborhood Hits	214	Shared Neighborhood Hits	34
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

BCR_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.069240 (rank : 131)
Query Neighborhood Hits	202	Target Neighborhood Hits	204	Shared Neighborhood Hits	24
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

BIG1_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.119241 (rank : 77)
Query Neighborhood Hits	202	Target Neighborhood Hits	76	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

BIG2_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.120365 (rank : 76)
Query Neighborhood Hits	202	Target Neighborhood Hits	66	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

BSN_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.055869 (rank : 168)
Query Neighborhood Hits	202	Target Neighborhood Hits	1537	Shared Neighborhood Hits	93
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CENA2_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.095037 (rank : 107)
Query Neighborhood Hits	202	Target Neighborhood Hits	68	Shared Neighborhood Hits	30
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

CEND3_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.108422 (rank : 88)
Query Neighborhood Hits	202	Target Neighborhood Hits	275	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CEND3_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.104568 (rank : 94)
Query Neighborhood Hits	202	Target Neighborhood Hits	228	Shared Neighborhood Hits	46
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

DDEF1_MOUSE
θ value	θ > 10 (rank : 213)	NC score	0.062912 (rank : 149)
Query Neighborhood Hits	202	Target Neighborhood Hits	592	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DDEF2_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.055953 (rank : 166)
Query Neighborhood Hits	202	Target Neighborhood Hits	599	Shared Neighborhood Hits	49
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.055719 (rank : 169)
Query Neighborhood Hits	202	Target Neighborhood Hits	625	Shared Neighborhood Hits	48
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDFL1_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.071724 (rank : 124)
Query Neighborhood Hits	202	Target Neighborhood Hits	353	Shared Neighborhood Hits	32
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DDFL1_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.064148 (rank : 144)
Query Neighborhood Hits	202	Target Neighborhood Hits	324	Shared Neighborhood Hits	25
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

DGKK_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.068404 (rank : 134)
Query Neighborhood Hits	202	Target Neighborhood Hits	378	Shared Neighborhood Hits	52
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

DYN1_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.067279 (rank : 139)
Query Neighborhood Hits	202	Target Neighborhood Hits	216	Shared Neighborhood Hits	50
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

DYN1_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.064017 (rank : 145)
Query Neighborhood Hits	202	Target Neighborhood Hits	168	Shared Neighborhood Hits	39
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

DYN3_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.089957 (rank : 109)
Query Neighborhood Hits	202	Target Neighborhood Hits	158	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

ECT2_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.052749 (rank : 181)
Query Neighborhood Hits	202	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ECT2_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.054519 (rank : 174)
Query Neighborhood Hits	202	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

FA47A_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.059276 (rank : 157)
Query Neighborhood Hits	202	Target Neighborhood Hits	451	Shared Neighborhood Hits	32
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FBX8_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.111082 (rank : 84)
Query Neighborhood Hits	202	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NRD0, Q6UWN4, Q9NRP5, Q9UKC4	Gene names	FBXO8, FBS, FBX8
Domain Architecture
Description	F-box only protein 8 (F-box/SEC7 protein FBS).

FBX8_MOUSE
θ value	θ > 10 (rank : 226)	NC score	0.111569 (rank : 82)
Query Neighborhood Hits	202	Target Neighborhood Hits	45	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QZN3	Gene names	Fbxo8, Fbx8
Domain Architecture
Description	F-box only protein 8.

FGD2_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.092106 (rank : 108)
Query Neighborhood Hits	202	Target Neighborhood Hits	151	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

FGD2_MOUSE
θ value	θ > 10 (rank : 228)	NC score	0.096599 (rank : 104)
Query Neighborhood Hits	202	Target Neighborhood Hits	163	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

FGD3_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.080860 (rank : 116)
Query Neighborhood Hits	202	Target Neighborhood Hits	249	Shared Neighborhood Hits	20
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

FGD3_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.103591 (rank : 95)
Query Neighborhood Hits	202	Target Neighborhood Hits	257	Shared Neighborhood Hits	31
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

FGD4_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.100271 (rank : 99)
Query Neighborhood Hits	202	Target Neighborhood Hits	219	Shared Neighborhood Hits	37
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD4_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.101634 (rank : 97)
Query Neighborhood Hits	202	Target Neighborhood Hits	227	Shared Neighborhood Hits	40
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FYCO1_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.050285 (rank : 195)
Query Neighborhood Hits	202	Target Neighborhood Hits	1149	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

GAB1_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.120599 (rank : 75)
Query Neighborhood Hits	202	Target Neighborhood Hits	279	Shared Neighborhood Hits	51
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GBF1_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.123373 (rank : 72)
Query Neighborhood Hits	202	Target Neighborhood Hits	142	Shared Neighborhood Hits	15
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

IQEC1_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.107810 (rank : 89)
Query Neighborhood Hits	202	Target Neighborhood Hits	76	Shared Neighborhood Hits	14
SwissProt Accessions	Q6DN90, O94863, Q96D85	Gene names	IQSEC1, ARFGEP100, BRAG2, KIAA0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein).

IQEC1_MOUSE
θ value	θ > 10 (rank : 237)	NC score	0.104781 (rank : 93)
Query Neighborhood Hits	202	Target Neighborhood Hits	54	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R0S2, Q3TZC3, Q5DU15	Gene names	Iqsec1, Kiaa0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1.

IQEC2_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.109393 (rank : 86)
Query Neighborhood Hits	202	Target Neighborhood Hits	403	Shared Neighborhood Hits	43
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.111421 (rank : 83)
Query Neighborhood Hits	202	Target Neighborhood Hits	417	Shared Neighborhood Hits	47
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC3_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.115252 (rank : 81)
Query Neighborhood Hits	202	Target Neighborhood Hits	125	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IQEC3_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.116847 (rank : 80)
Query Neighborhood Hits	202	Target Neighborhood Hits	274	Shared Neighborhood Hits	37
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

K1914_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.068045 (rank : 137)
Query Neighborhood Hits	202	Target Neighborhood Hits	255	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N4X5, Q8TB54, Q96PX4, Q96SY5	Gene names	KIAA1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

K1914_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.059327 (rank : 156)
Query Neighborhood Hits	202	Target Neighborhood Hits	216	Shared Neighborhood Hits	32
SwissProt Accessions	Q5DTU0, Q8BID1, Q8K2G0	Gene names	Kiaa1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

MTMR5_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.069960 (rank : 130)
Query Neighborhood Hits	202	Target Neighborhood Hits	141	Shared Neighborhood Hits	39
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

MUC7_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.053627 (rank : 176)
Query Neighborhood Hits	202	Target Neighborhood Hits	538	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NCOA6_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.051463 (rank : 184)
Query Neighborhood Hits	202	Target Neighborhood Hits	1076	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

OGFR_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.059781 (rank : 153)
Query Neighborhood Hits	202	Target Neighborhood Hits	1582	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

OSB11_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.050748 (rank : 190)
Query Neighborhood Hits	202	Target Neighborhood Hits	60	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSB11_MOUSE
θ value	θ > 10 (rank : 249)	NC score	0.051350 (rank : 186)
Query Neighborhood Hits	202	Target Neighborhood Hits	71	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSBL9_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.071700 (rank : 125)
Query Neighborhood Hits	202	Target Neighborhood Hits	138	Shared Neighborhood Hits	44
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

PCLO_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.058295 (rank : 158)
Query Neighborhood Hits	202	Target Neighborhood Hits	2046	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PKHA3_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.095806 (rank : 105)
Query Neighborhood Hits	202	Target Neighborhood Hits	66	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PKHA3_MOUSE
θ value	θ > 10 (rank : 253)	NC score	0.107444 (rank : 90)
Query Neighborhood Hits	202	Target Neighborhood Hits	67	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PKHF1_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.060024 (rank : 152)
Query Neighborhood Hits	202	Target Neighborhood Hits	76	Shared Neighborhood Hits	9
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

PKHF1_MOUSE
θ value	θ > 10 (rank : 255)	NC score	0.060467 (rank : 151)
Query Neighborhood Hits	202	Target Neighborhood Hits	80	Shared Neighborhood Hits	11
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

PKHF2_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.063225 (rank : 148)
Query Neighborhood Hits	202	Target Neighborhood Hits	75	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

PKHF2_MOUSE
θ value	θ > 10 (rank : 257)	NC score	0.065540 (rank : 142)
Query Neighborhood Hits	202	Target Neighborhood Hits	77	Shared Neighborhood Hits	16
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

PLEK2_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.159591 (rank : 55)
Query Neighborhood Hits	202	Target Neighborhood Hits	101	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_MOUSE
θ value	θ > 10 (rank : 259)	NC score	0.152676 (rank : 60)
Query Neighborhood Hits	202	Target Neighborhood Hits	96	Shared Neighborhood Hits	58
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PLEK_MOUSE
θ value	θ > 10 (rank : 260)	NC score	0.201379 (rank : 36)
Query Neighborhood Hits	202	Target Neighborhood Hits	109	Shared Neighborhood Hits	56
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

PRB3_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.071908 (rank : 123)
Query Neighborhood Hits	202	Target Neighborhood Hits	318	Shared Neighborhood Hits	37
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.071171 (rank : 127)
Query Neighborhood Hits	202	Target Neighborhood Hits	330	Shared Neighborhood Hits	40
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PREX1_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.054693 (rank : 172)
Query Neighborhood Hits	202	Target Neighborhood Hits	177	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

PRP1_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.081170 (rank : 115)
Query Neighborhood Hits	202	Target Neighborhood Hits	385	Shared Neighborhood Hits	43
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRRT3_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.055933 (rank : 167)
Query Neighborhood Hits	202	Target Neighborhood Hits	998	Shared Neighborhood Hits	57
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PSD3_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.176912 (rank : 42)
Query Neighborhood Hits	202	Target Neighborhood Hits	75	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NYI0, Q9Y2F1	Gene names	PSD3, EFA6R, HCA67, KIAA0942
Domain Architecture
Description	PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).

PSD4_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.138389 (rank : 64)
Query Neighborhood Hits	202	Target Neighborhood Hits	178	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

PSD4_MOUSE
θ value	θ > 10 (rank : 268)	NC score	0.128252 (rank : 69)
Query Neighborhood Hits	202	Target Neighborhood Hits	78	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44	Gene names	Psd4
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).

RASA1_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.081736 (rank : 113)
Query Neighborhood Hits	202	Target Neighborhood Hits	258	Shared Neighborhood Hits	36
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RASA2_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.056575 (rank : 164)
Query Neighborhood Hits	202	Target Neighborhood Hits	157	Shared Neighborhood Hits	32
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RASA3_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.067300 (rank : 138)
Query Neighborhood Hits	202	Target Neighborhood Hits	166	Shared Neighborhood Hits	39
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

RASA3_MOUSE
θ value	θ > 10 (rank : 272)	NC score	0.057492 (rank : 160)
Query Neighborhood Hits	202	Target Neighborhood Hits	144	Shared Neighborhood Hits	34
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

RBP1_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.050141 (rank : 196)
Query Neighborhood Hits	202	Target Neighborhood Hits	521	Shared Neighborhood Hits	35
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RHG26_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.050334 (rank : 194)
Query Neighborhood Hits	202	Target Neighborhood Hits	281	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

SFPQ_MOUSE
θ value	θ > 10 (rank : 275)	NC score	0.051378 (rank : 185)
Query Neighborhood Hits	202	Target Neighborhood Hits	958	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SMAP1_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.050376 (rank : 193)
Query Neighborhood Hits	202	Target Neighborhood Hits	120	Shared Neighborhood Hits	13
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMP1L_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.050524 (rank : 191)
Query Neighborhood Hits	202	Target Neighborhood Hits	74	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SRRM1_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.079798 (rank : 117)
Query Neighborhood Hits	202	Target Neighborhood Hits	690	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.077700 (rank : 121)
Query Neighborhood Hits	202	Target Neighborhood Hits	966	Shared Neighborhood Hits	72
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.066188 (rank : 141)
Query Neighborhood Hits	202	Target Neighborhood Hits	1296	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.056582 (rank : 163)
Query Neighborhood Hits	202	Target Neighborhood Hits	1470	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SWP70_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.122644 (rank : 73)
Query Neighborhood Hits	202	Target Neighborhood Hits	973	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.117747 (rank : 78)
Query Neighborhood Hits	202	Target Neighborhood Hits	1097	Shared Neighborhood Hits	95
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

WASIP_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.066754 (rank : 140)
Query Neighborhood Hits	202	Target Neighborhood Hits	458	Shared Neighborhood Hits	47
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.064738 (rank : 143)
Query Neighborhood Hits	202	Target Neighborhood Hits	392	Shared Neighborhood Hits	42
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WASL_MOUSE
θ value	θ > 10 (rank : 286)	NC score	0.050802 (rank : 189)
Query Neighborhood Hits	202	Target Neighborhood Hits	339	Shared Neighborhood Hits	38
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

Hits sorted by NC score

PKHA4_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	202	Target Neighborhood Hits	202	Shared Neighborhood Hits	202
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA4_HUMAN
NC score	0.948125 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	202	Target Neighborhood Hits	283	Shared Neighborhood Hits	134
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA6_HUMAN
NC score	0.708256 (rank : 3)	θ value	5.22648e-32 (rank : 4)
Query Neighborhood Hits	202	Target Neighborhood Hits	556	Shared Neighborhood Hits	104
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
NC score	0.702313 (rank : 4)	θ value	8.91499e-32 (rank : 5)
Query Neighborhood Hits	202	Target Neighborhood Hits	591	Shared Neighborhood Hits	110
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA5_HUMAN
NC score	0.660779 (rank : 5)	θ value	9.52487e-34 (rank : 3)
Query Neighborhood Hits	202	Target Neighborhood Hits	455	Shared Neighborhood Hits	104
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

CNKR1_HUMAN
NC score	0.532983 (rank : 6)	θ value	2.28291e-11 (rank : 6)
Query Neighborhood Hits	202	Target Neighborhood Hits	154	Shared Neighborhood Hits	61
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CNKR2_HUMAN
NC score	0.441196 (rank : 7)	θ value	2.61198e-07 (rank : 7)
Query Neighborhood Hits	202	Target Neighborhood Hits	197	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
NC score	0.441076 (rank : 8)	θ value	2.61198e-07 (rank : 8)
Query Neighborhood Hits	202	Target Neighborhood Hits	197	Shared Neighborhood Hits	54
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CYH3_HUMAN
NC score	0.350310 (rank : 9)	θ value	2.44474e-05 (rank : 15)
Query Neighborhood Hits	202	Target Neighborhood Hits	137	Shared Neighborhood Hits	71
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH1_HUMAN
NC score	0.349389 (rank : 10)	θ value	2.44474e-05 (rank : 13)
Query Neighborhood Hits	202	Target Neighborhood Hits	184	Shared Neighborhood Hits	78
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH1_MOUSE
NC score	0.348747 (rank : 11)	θ value	2.44474e-05 (rank : 14)
Query Neighborhood Hits	202	Target Neighborhood Hits	176	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH2_HUMAN
NC score	0.344893 (rank : 12)	θ value	1.09739e-05 (rank : 11)
Query Neighborhood Hits	202	Target Neighborhood Hits	175	Shared Neighborhood Hits	73
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
NC score	0.344684 (rank : 13)	θ value	1.09739e-05 (rank : 12)
Query Neighborhood Hits	202	Target Neighborhood Hits	171	Shared Neighborhood Hits	72
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

PKHA1_HUMAN
NC score	0.344521 (rank : 14)	θ value	0.00175202 (rank : 25)
Query Neighborhood Hits	202	Target Neighborhood Hits	127	Shared Neighborhood Hits	63
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

CYH3_MOUSE
NC score	0.340475 (rank : 15)	θ value	0.000461057 (rank : 19)
Query Neighborhood Hits	202	Target Neighborhood Hits	148	Shared Neighborhood Hits	72
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

CYH4_HUMAN
NC score	0.336442 (rank : 16)	θ value	0.000461057 (rank : 20)
Query Neighborhood Hits	202	Target Neighborhood Hits	135	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

CYH4_MOUSE
NC score	0.333063 (rank : 17)	θ value	0.00102713 (rank : 22)
Query Neighborhood Hits	202	Target Neighborhood Hits	134	Shared Neighborhood Hits	65
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

PKHA1_MOUSE
NC score	0.326054 (rank : 18)	θ value	0.163984 (rank : 64)
Query Neighborhood Hits	202	Target Neighborhood Hits	120	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA2_MOUSE
NC score	0.321597 (rank : 19)	θ value	0.0252991 (rank : 43)
Query Neighborhood Hits	202	Target Neighborhood Hits	116	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PKHA2_HUMAN
NC score	0.310767 (rank : 20)	θ value	0.0431538 (rank : 51)
Query Neighborhood Hits	202	Target Neighborhood Hits	119	Shared Neighborhood Hits	66
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

3BP2_HUMAN
NC score	0.308497 (rank : 21)	θ value	0.00228821 (rank : 26)
Query Neighborhood Hits	202	Target Neighborhood Hits	296	Shared Neighborhood Hits	50
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

3BP2_MOUSE
NC score	0.304326 (rank : 22)	θ value	0.0113563 (rank : 33)
Query Neighborhood Hits	202	Target Neighborhood Hits	142	Shared Neighborhood Hits	41
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

RHG25_MOUSE
NC score	0.289214 (rank : 23)	θ value	2.61198e-07 (rank : 9)
Query Neighborhood Hits	202	Target Neighborhood Hits	492	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_HUMAN
NC score	0.286715 (rank : 24)	θ value	3.41135e-07 (rank : 10)
Query Neighborhood Hits	202	Target Neighborhood Hits	550	Shared Neighborhood Hits	88
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

PKHB2_MOUSE
NC score	0.259790 (rank : 25)	θ value	0.163984 (rank : 66)
Query Neighborhood Hits	202	Target Neighborhood Hits	48	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QZC7, Q3UDH6, Q8C4I4, Q8CA27	Gene names	Plekhb2, Evt2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

MRIP_MOUSE
NC score	0.246533 (rank : 26)	θ value	0.00020696 (rank : 17)
Query Neighborhood Hits	202	Target Neighborhood Hits	569	Shared Neighborhood Hits	85
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

PKHB2_HUMAN
NC score	0.243989 (rank : 27)	θ value	0.365318 (rank : 78)
Query Neighborhood Hits	202	Target Neighborhood Hits	54	Shared Neighborhood Hits	39
SwissProt Accessions	Q96CS7, Q86W37, Q9BV75, Q9NWK1	Gene names	PLEKHB2, EVT2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

PKHB1_HUMAN
NC score	0.235654 (rank : 28)	θ value	0.163984 (rank : 65)
Query Neighborhood Hits	202	Target Neighborhood Hits	46	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UF11, Q9UBF5, Q9UI37, Q9UI44	Gene names	PLEKHB1, KPL1, PHR1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

ANLN_HUMAN
NC score	0.232122 (rank : 29)	θ value	0.00390308 (rank : 29)
Query Neighborhood Hits	202	Target Neighborhood Hits	222	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

MRIP_HUMAN
NC score	0.230856 (rank : 30)	θ value	0.00298849 (rank : 28)
Query Neighborhood Hits	202	Target Neighborhood Hits	578	Shared Neighborhood Hits	86
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

PLEK_HUMAN
NC score	0.229429 (rank : 31)	θ value	4.03905 (rank : 149)
Query Neighborhood Hits	202	Target Neighborhood Hits	110	Shared Neighborhood Hits	59
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PKHB1_MOUSE
NC score	0.216593 (rank : 32)	θ value	0.47712 (rank : 85)
Query Neighborhood Hits	202	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QYE9, Q9QYB3, Q9QYB4, Q9QYD2, Q9QYD3	Gene names	Plekhb1, Phr1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

DAPP1_MOUSE
NC score	0.208651 (rank : 33)	θ value	1.81305 (rank : 113)
Query Neighborhood Hits	202	Target Neighborhood Hits	225	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

FGD5_MOUSE
NC score	0.203640 (rank : 34)	θ value	0.00509761 (rank : 32)
Query Neighborhood Hits	202	Target Neighborhood Hits	170	Shared Neighborhood Hits	38
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

DAPP1_HUMAN
NC score	0.202502 (rank : 35)	θ value	3.0926 (rank : 131)
Query Neighborhood Hits	202	Target Neighborhood Hits	227	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

PLEK_MOUSE
NC score	0.201379 (rank : 36)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	202	Target Neighborhood Hits	109	Shared Neighborhood Hits	56
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

FGD5_HUMAN
NC score	0.199357 (rank : 37)	θ value	0.00390308 (rank : 30)
Query Neighborhood Hits	202	Target Neighborhood Hits	235	Shared Neighborhood Hits	41
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

TARA_MOUSE
NC score	0.199172 (rank : 38)	θ value	0.00390308 (rank : 31)
Query Neighborhood Hits	202	Target Neighborhood Hits	1133	Shared Neighborhood Hits	102
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ANLN_MOUSE
NC score	0.198420 (rank : 39)	θ value	0.0252991 (rank : 39)
Query Neighborhood Hits	202	Target Neighborhood Hits	297	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

CENB2_HUMAN
NC score	0.181759 (rank : 40)	θ value	0.0431538 (rank : 48)
Query Neighborhood Hits	202	Target Neighborhood Hits	425	Shared Neighborhood Hits	60
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

FGD6_MOUSE
NC score	0.180308 (rank : 41)	θ value	0.0330416 (rank : 47)
Query Neighborhood Hits	202	Target Neighborhood Hits	282	Shared Neighborhood Hits	50
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

PSD3_HUMAN
NC score	0.176912 (rank : 42)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	202	Target Neighborhood Hits	75	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NYI0, Q9Y2F1	Gene names	PSD3, EFA6R, HCA67, KIAA0942
Domain Architecture
Description	PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).

FARP2_MOUSE
NC score	0.175194 (rank : 43)	θ value	0.000270298 (rank : 18)
Query Neighborhood Hits	202	Target Neighborhood Hits	209	Shared Neighborhood Hits	50
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

CENB5_HUMAN
NC score	0.172689 (rank : 44)	θ value	0.0330416 (rank : 44)
Query Neighborhood Hits	202	Target Neighborhood Hits	395	Shared Neighborhood Hits	61
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

FARP2_HUMAN
NC score	0.170540 (rank : 45)	θ value	0.00102713 (rank : 23)
Query Neighborhood Hits	202	Target Neighborhood Hits	240	Shared Neighborhood Hits	50
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

DGKH_HUMAN
NC score	0.169408 (rank : 46)	θ value	0.00298849 (rank : 27)
Query Neighborhood Hits	202	Target Neighborhood Hits	255	Shared Neighborhood Hits	56
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

FARP1_HUMAN
NC score	0.169157 (rank : 47)	θ value	0.0148317 (rank : 34)
Query Neighborhood Hits	202	Target Neighborhood Hits	241	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

CENB1_HUMAN
NC score	0.167980 (rank : 48)	θ value	0.00102713 (rank : 21)
Query Neighborhood Hits	202	Target Neighborhood Hits	383	Shared Neighborhood Hits	60
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CEND1_HUMAN
NC score	0.166705 (rank : 49)	θ value	0.0330416 (rank : 45)
Query Neighborhood Hits	202	Target Neighborhood Hits	284	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

FGD6_HUMAN
NC score	0.166600 (rank : 50)	θ value	0.62314 (rank : 87)
Query Neighborhood Hits	202	Target Neighborhood Hits	237	Shared Neighborhood Hits	44
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

CEND2_HUMAN
NC score	0.165340 (rank : 51)	θ value	0.0330416 (rank : 46)
Query Neighborhood Hits	202	Target Neighborhood Hits	166	Shared Neighborhood Hits	52
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

CENA1_HUMAN
NC score	0.164565 (rank : 52)	θ value	0.0252991 (rank : 40)
Query Neighborhood Hits	202	Target Neighborhood Hits	87	Shared Neighborhood Hits	44
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

TARA_HUMAN
NC score	0.160794 (rank : 53)	θ value	0.0563607 (rank : 54)
Query Neighborhood Hits	202	Target Neighborhood Hits	1626	Shared Neighborhood Hits	118
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

GNRP_MOUSE
NC score	0.160624 (rank : 54)	θ value	0.0148317 (rank : 36)
Query Neighborhood Hits	202	Target Neighborhood Hits	191	Shared Neighborhood Hits	52
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

PLEK2_HUMAN
NC score	0.159591 (rank : 55)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	202	Target Neighborhood Hits	101	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

GNRP_HUMAN
NC score	0.157877 (rank : 56)	θ value	0.0736092 (rank : 55)
Query Neighborhood Hits	202	Target Neighborhood Hits	239	Shared Neighborhood Hits	50
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

GAB2_HUMAN
NC score	0.156691 (rank : 57)	θ value	0.47712 (rank : 82)
Query Neighborhood Hits	202	Target Neighborhood Hits	188	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

FGD1_MOUSE
NC score	0.156541 (rank : 58)	θ value	0.0148317 (rank : 35)
Query Neighborhood Hits	202	Target Neighborhood Hits	387	Shared Neighborhood Hits	50
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_HUMAN
NC score	0.154671 (rank : 59)	θ value	0.0252991 (rank : 42)
Query Neighborhood Hits	202	Target Neighborhood Hits	367	Shared Neighborhood Hits	47
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

PLEK2_MOUSE
NC score	0.152676 (rank : 60)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	202	Target Neighborhood Hits	96	Shared Neighborhood Hits	58
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

GAB2_MOUSE
NC score	0.152442 (rank : 61)	θ value	1.38821 (rank : 103)
Query Neighborhood Hits	202	Target Neighborhood Hits	220	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

OSBP1_HUMAN
NC score	0.151531 (rank : 62)	θ value	0.0431538 (rank : 50)
Query Neighborhood Hits	202	Target Neighborhood Hits	180	Shared Neighborhood Hits	50
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

CEND1_MOUSE
NC score	0.138394 (rank : 63)	θ value	0.125558 (rank : 59)
Query Neighborhood Hits	202	Target Neighborhood Hits	260	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

PSD4_HUMAN
NC score	0.138389 (rank : 64)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	202	Target Neighborhood Hits	178	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

PHLB1_MOUSE
NC score	0.135977 (rank : 65)	θ value	2.36792 (rank : 123)
Query Neighborhood Hits	202	Target Neighborhood Hits	678	Shared Neighborhood Hits	82
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PHLB1_HUMAN
NC score	0.132591 (rank : 66)	θ value	0.0961366 (rank : 58)
Query Neighborhood Hits	202	Target Neighborhood Hits	1038	Shared Neighborhood Hits	86
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

CENA2_HUMAN
NC score	0.132155 (rank : 67)	θ value	0.279714 (rank : 69)
Query Neighborhood Hits	202	Target Neighborhood Hits	83	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

C43BP_MOUSE
NC score	0.130372 (rank : 68)	θ value	6.88961 (rank : 172)
Query Neighborhood Hits	202	Target Neighborhood Hits	91	Shared Neighborhood Hits	47
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

PSD4_MOUSE
NC score	0.128252 (rank : 69)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	202	Target Neighborhood Hits	78	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44	Gene names	Psd4
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).

C43BP_HUMAN
NC score	0.127346 (rank : 70)	θ value	5.27518 (rank : 157)
Query Neighborhood Hits	202	Target Neighborhood Hits	87	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

MYO10_HUMAN
NC score	0.123949 (rank : 71)	θ value	0.000121331 (rank : 16)
Query Neighborhood Hits	202	Target Neighborhood Hits	920	Shared Neighborhood Hits	98
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

GBF1_HUMAN
NC score	0.123373 (rank : 72)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	202	Target Neighborhood Hits	142	Shared Neighborhood Hits	15
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

SWP70_HUMAN
NC score	0.122644 (rank : 73)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	202	Target Neighborhood Hits	973	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

GAB1_MOUSE
NC score	0.121147 (rank : 74)	θ value	6.88961 (rank : 176)
Query Neighborhood Hits	202	Target Neighborhood Hits	233	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAB1_HUMAN
NC score	0.120599 (rank : 75)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	202	Target Neighborhood Hits	279	Shared Neighborhood Hits	51
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

BIG2_HUMAN
NC score	0.120365 (rank : 76)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	202	Target Neighborhood Hits	66	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

BIG1_HUMAN
NC score	0.119241 (rank : 77)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	202	Target Neighborhood Hits	76	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

SWP70_MOUSE
NC score	0.117747 (rank : 78)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	202	Target Neighborhood Hits	1097	Shared Neighborhood Hits	95
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

OSBP2_HUMAN
NC score	0.117438 (rank : 79)	θ value	1.06291 (rank : 97)
Query Neighborhood Hits	202	Target Neighborhood Hits	154	Shared Neighborhood Hits	49
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

IQEC3_MOUSE
NC score	0.116847 (rank : 80)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	202	Target Neighborhood Hits	274	Shared Neighborhood Hits	37
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IQEC3_HUMAN
NC score	0.115252 (rank : 81)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	202	Target Neighborhood Hits	125	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

FBX8_MOUSE
NC score	0.111569 (rank : 82)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	202	Target Neighborhood Hits	45	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QZN3	Gene names	Fbxo8, Fbx8
Domain Architecture
Description	F-box only protein 8.

IQEC2_MOUSE
NC score	0.111421 (rank : 83)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	202	Target Neighborhood Hits	417	Shared Neighborhood Hits	47
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

FBX8_HUMAN
NC score	0.111082 (rank : 84)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	202	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NRD0, Q6UWN4, Q9NRP5, Q9UKC4	Gene names	FBXO8, FBS, FBX8
Domain Architecture
Description	F-box only protein 8 (F-box/SEC7 protein FBS).

OSBP2_MOUSE
NC score	0.109662 (rank : 85)	θ value	0.279714 (rank : 71)
Query Neighborhood Hits	202	Target Neighborhood Hits	150	Shared Neighborhood Hits	44
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

IQEC2_HUMAN
NC score	0.109393 (rank : 86)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	202	Target Neighborhood Hits	403	Shared Neighborhood Hits	43
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

DOCK9_MOUSE
NC score	0.108952 (rank : 87)	θ value	0.0431538 (rank : 49)
Query Neighborhood Hits	202	Target Neighborhood Hits	79	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BIK4, Q921Y6	Gene names	Dock9, D14Wsu89e, Kiaa1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

CEND3_HUMAN
NC score	0.108422 (rank : 88)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	202	Target Neighborhood Hits	275	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

IQEC1_HUMAN
NC score	0.107810 (rank : 89)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	202	Target Neighborhood Hits	76	Shared Neighborhood Hits	14
SwissProt Accessions	Q6DN90, O94863, Q96D85	Gene names	IQSEC1, ARFGEP100, BRAG2, KIAA0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein).

PKHA3_MOUSE
NC score	0.107444 (rank : 90)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	202	Target Neighborhood Hits	67	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

DOCK9_HUMAN
NC score	0.106346 (rank : 91)	θ value	0.125558 (rank : 60)
Query Neighborhood Hits	202	Target Neighborhood Hits	82	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BZ29, Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26, Q9BZ27, Q9BZ28, Q9UPU4	Gene names	DOCK9, KIAA1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

DGKD_HUMAN
NC score	0.105112 (rank : 92)	θ value	0.21417 (rank : 67)
Query Neighborhood Hits	202	Target Neighborhood Hits	231	Shared Neighborhood Hits	34
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

IQEC1_MOUSE
NC score	0.104781 (rank : 93)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	202	Target Neighborhood Hits	54	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R0S2, Q3TZC3, Q5DU15	Gene names	Iqsec1, Kiaa0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1.

CEND3_MOUSE
NC score	0.104568 (rank : 94)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	202	Target Neighborhood Hits	228	Shared Neighborhood Hits	46
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

FGD3_MOUSE
NC score	0.103591 (rank : 95)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	202	Target Neighborhood Hits	257	Shared Neighborhood Hits	31
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

PHLB2_MOUSE
NC score	0.101667 (rank : 96)	θ value	4.03905 (rank : 148)
Query Neighborhood Hits	202	Target Neighborhood Hits	1016	Shared Neighborhood Hits	74
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

FGD4_MOUSE
NC score	0.101634 (rank : 97)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	202	Target Neighborhood Hits	227	Shared Neighborhood Hits	40
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

MTMRD_HUMAN
NC score	0.101337 (rank : 98)	θ value	0.125558 (rank : 63)
Query Neighborhood Hits	202	Target Neighborhood Hits	135	Shared Neighborhood Hits	44
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

FGD4_HUMAN
NC score	0.100271 (rank : 99)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	202	Target Neighborhood Hits	219	Shared Neighborhood Hits	37
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

DYN2_HUMAN
NC score	0.100218 (rank : 100)	θ value	1.38821 (rank : 99)
Query Neighborhood Hits	202	Target Neighborhood Hits	112	Shared Neighborhood Hits	43
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

PHLB2_HUMAN
NC score	0.100113 (rank : 101)	θ value	5.27518 (rank : 165)
Query Neighborhood Hits	202	Target Neighborhood Hits	964	Shared Neighborhood Hits	69
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

DYN2_MOUSE
NC score	0.099552 (rank : 102)	θ value	1.38821 (rank : 100)
Query Neighborhood Hits	202	Target Neighborhood Hits	104	Shared Neighborhood Hits	40
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

CT151_HUMAN
NC score	0.099453 (rank : 103)	θ value	0.0193708 (rank : 37)
Query Neighborhood Hits	202	Target Neighborhood Hits	382	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

FGD2_MOUSE
NC score	0.096599 (rank : 104)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	202	Target Neighborhood Hits	163	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

PKHA3_HUMAN
NC score	0.095806 (rank : 105)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	202	Target Neighborhood Hits	66	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

DOC10_HUMAN
NC score	0.095333 (rank : 106)	θ value	3.0926 (rank : 133)
Query Neighborhood Hits	202	Target Neighborhood Hits	88	Shared Neighborhood Hits	23
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).

CENA2_MOUSE
NC score	0.095037 (rank : 107)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	202	Target Neighborhood Hits	68	Shared Neighborhood Hits	30
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

FGD2_HUMAN
NC score	0.092106 (rank : 108)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	202	Target Neighborhood Hits	151	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

DYN3_HUMAN
NC score	0.089957 (rank : 109)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	202	Target Neighborhood Hits	158	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

FA47B_HUMAN
NC score	0.088475 (rank : 110)	θ value	0.0252991 (rank : 41)
Query Neighborhood Hits	202	Target Neighborhood Hits	431	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

CAPS2_MOUSE
NC score	0.084329 (rank : 111)	θ value	1.81305 (rank : 112)
Query Neighborhood Hits	202	Target Neighborhood Hits	78	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BYR5, O08903, Q66JM7, Q6PCL7, Q76I88, Q7TMM6, Q80ZV8, Q8BL25, Q8BY04, Q8K3K6	Gene names	Cadps2, Caps2
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2).

PRP2_MOUSE
NC score	0.082977 (rank : 112)	θ value	4.03905 (rank : 150)
Query Neighborhood Hits	202	Target Neighborhood Hits	347	Shared Neighborhood Hits	42
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

RASA1_HUMAN
NC score	0.081736 (rank : 113)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	202	Target Neighborhood Hits	258	Shared Neighborhood Hits	36
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

TBCD2_HUMAN
NC score	0.081453 (rank : 114)	θ value	4.03905 (rank : 155)
Query Neighborhood Hits	202	Target Neighborhood Hits	419	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

PRP1_HUMAN
NC score	0.081170 (rank : 115)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	202	Target Neighborhood Hits	385	Shared Neighborhood Hits	43
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

FGD3_HUMAN
NC score	0.080860 (rank : 116)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	202	Target Neighborhood Hits	249	Shared Neighborhood Hits	20
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

SRRM1_HUMAN
NC score	0.079798 (rank : 117)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	202	Target Neighborhood Hits	690	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

CAPS1_MOUSE
NC score	0.079348 (rank : 118)	θ value	3.0926 (rank : 128)
Query Neighborhood Hits	202	Target Neighborhood Hits	93	Shared Neighborhood Hits	24
SwissProt Accessions	Q80TJ1, Q3TSP2, Q61374, Q6AXB4, Q6PGF0	Gene names	Cadps, Caps, Caps1, Kiaa1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

CAPS1_HUMAN
NC score	0.078831 (rank : 119)	θ value	3.0926 (rank : 127)
Query Neighborhood Hits	202	Target Neighborhood Hits	86	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ULU8, Q13339, Q6GQQ6, Q8N2Z5, Q8N3M7, Q8NFR0, Q96BC2	Gene names	CADPS, CAPS, CAPS1, KIAA1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

CAPS2_HUMAN
NC score	0.077937 (rank : 120)	θ value	3.0926 (rank : 129)
Query Neighborhood Hits	202	Target Neighborhood Hits	81	Shared Neighborhood Hits	29
SwissProt Accessions	Q86UW7, Q658Q2, Q7Z5T7, Q8IZW9, Q8N7M4, Q9H6P4, Q9HCI1, Q9NWK8	Gene names	CADPS2, CAPS2, KIAA1591
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2).

SRRM1_MOUSE
NC score	0.077700 (rank : 121)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	202	Target Neighborhood Hits	966	Shared Neighborhood Hits	72
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

IASPP_MOUSE
NC score	0.074514 (rank : 122)	θ value	0.00175202 (rank : 24)
Query Neighborhood Hits	202	Target Neighborhood Hits	1024	Shared Neighborhood Hits	48
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

PRB3_HUMAN
NC score	0.071908 (rank : 123)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	202	Target Neighborhood Hits	318	Shared Neighborhood Hits	37
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

DDFL1_HUMAN
NC score	0.071724 (rank : 124)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	202	Target Neighborhood Hits	353	Shared Neighborhood Hits	32
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

OSBL9_HUMAN
NC score	0.071700 (rank : 125)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	202	Target Neighborhood Hits	138	Shared Neighborhood Hits	44
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

RIMB1_HUMAN
NC score	0.071585 (rank : 126)	θ value	0.62314 (rank : 89)
Query Neighborhood Hits	202	Target Neighborhood Hits	1479	Shared Neighborhood Hits	66
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

PRB4S_HUMAN
NC score	0.071171 (rank : 127)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	202	Target Neighborhood Hits	330	Shared Neighborhood Hits	40
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

ABR_HUMAN
NC score	0.070976 (rank : 128)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	202	Target Neighborhood Hits	166	Shared Neighborhood Hits	21
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

DIDO1_HUMAN
NC score	0.070934 (rank : 129)	θ value	0.47712 (rank : 81)
Query Neighborhood Hits	202	Target Neighborhood Hits	960	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

MTMR5_HUMAN
NC score	0.069960 (rank : 130)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	202	Target Neighborhood Hits	141	Shared Neighborhood Hits	39
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

BCR_HUMAN
NC score	0.069240 (rank : 131)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	202	Target Neighborhood Hits	204	Shared Neighborhood Hits	24
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

RIMB1_MOUSE
NC score	0.068581 (rank : 132)	θ value	0.0193708 (rank : 38)
Query Neighborhood Hits	202	Target Neighborhood Hits	1376	Shared Neighborhood Hits	58
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ZNHI4_MOUSE
NC score	0.068532 (rank : 133)	θ value	0.279714 (rank : 73)
Query Neighborhood Hits	202	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	Q99PT3, Q9CY38	Gene names	Znhit4, Hmga1l4, Papa1
Domain Architecture	No domain graphic available
Description	Zinc finger HIT domain-containing protein 4 (PAP-1-associated protein 1) (PAPA-1) (High mobility group AT-hook 1-like 4).

DGKK_HUMAN
NC score	0.068404 (rank : 134)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	202	Target Neighborhood Hits	378	Shared Neighborhood Hits	52
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

NCOA6_HUMAN
NC score	0.068269 (rank : 135)	θ value	0.47712 (rank : 84)
Query Neighborhood Hits	202	Target Neighborhood Hits	1202	Shared Neighborhood Hits	67
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

RASA2_MOUSE
NC score	0.068051 (rank : 136)	θ value	6.88961 (rank : 182)
Query Neighborhood Hits	202	Target Neighborhood Hits	159	Shared Neighborhood Hits	35
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

K1914_HUMAN
NC score	0.068045 (rank : 137)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	202	Target Neighborhood Hits	255	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N4X5, Q8TB54, Q96PX4, Q96SY5	Gene names	KIAA1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

RASA3_HUMAN
NC score	0.067300 (rank : 138)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	202	Target Neighborhood Hits	166	Shared Neighborhood Hits	39
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

DYN1_HUMAN
NC score	0.067279 (rank : 139)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	202	Target Neighborhood Hits	216	Shared Neighborhood Hits	50
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

WASIP_HUMAN
NC score	0.066754 (rank : 140)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	202	Target Neighborhood Hits	458	Shared Neighborhood Hits	47
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

SRRM2_HUMAN
NC score	0.066188 (rank : 141)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	202	Target Neighborhood Hits	1296	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

PKHF2_MOUSE
NC score	0.065540 (rank : 142)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	202	Target Neighborhood Hits	77	Shared Neighborhood Hits	16
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

WASIP_MOUSE
NC score	0.064738 (rank : 143)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	202	Target Neighborhood Hits	392	Shared Neighborhood Hits	42
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

DDFL1_MOUSE
NC score	0.064148 (rank : 144)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	202	Target Neighborhood Hits	324	Shared Neighborhood Hits	25
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

DYN1_MOUSE
NC score	0.064017 (rank : 145)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	202	Target Neighborhood Hits	168	Shared Neighborhood Hits	39
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

SF3B1_HUMAN
NC score	0.063509 (rank : 146)	θ value	0.813845 (rank : 93)
Query Neighborhood Hits	202	Target Neighborhood Hits	341	Shared Neighborhood Hits	28
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
NC score	0.063403 (rank : 147)	θ value	0.813845 (rank : 94)
Query Neighborhood Hits	202	Target Neighborhood Hits	352	Shared Neighborhood Hits	27
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

PKHF2_HUMAN
NC score	0.063225 (rank : 148)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	202	Target Neighborhood Hits	75	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

DDEF1_MOUSE
NC score	0.062912 (rank : 149)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	202	Target Neighborhood Hits	592	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

IASPP_HUMAN
NC score	0.061599 (rank : 150)	θ value	0.279714 (rank : 70)
Query Neighborhood Hits	202	Target Neighborhood Hits	688	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

PKHF1_MOUSE
NC score	0.060467 (rank : 151)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	202	Target Neighborhood Hits	80	Shared Neighborhood Hits	11
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

PKHF1_HUMAN
NC score	0.060024 (rank : 152)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	202	Target Neighborhood Hits	76	Shared Neighborhood Hits	9
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

OGFR_HUMAN
NC score	0.059781 (rank : 153)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	202	Target Neighborhood Hits	1582	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

TIAM1_HUMAN
NC score	0.059723 (rank : 154)	θ value	8.99809 (rank : 199)
Query Neighborhood Hits	202	Target Neighborhood Hits	225	Shared Neighborhood Hits	30
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

ALEX_HUMAN
NC score	0.059384 (rank : 155)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	202	Target Neighborhood Hits	361	Shared Neighborhood Hits	35
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

K1914_MOUSE
NC score	0.059327 (rank : 156)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	202	Target Neighborhood Hits	216	Shared Neighborhood Hits	32
SwissProt Accessions	Q5DTU0, Q8BID1, Q8K2G0	Gene names	Kiaa1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

FA47A_HUMAN
NC score	0.059276 (rank : 157)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	202	Target Neighborhood Hits	451	Shared Neighborhood Hits	32
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

PCLO_HUMAN
NC score	0.058295 (rank : 158)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	202	Target Neighborhood Hits	2046	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

EP300_HUMAN
NC score	0.057534 (rank : 159)	θ value	0.0563607 (rank : 52)
Query Neighborhood Hits	202	Target Neighborhood Hits	821	Shared Neighborhood Hits	50
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

RASA3_MOUSE
NC score	0.057492 (rank : 160)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	202	Target Neighborhood Hits	144	Shared Neighborhood Hits	34
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

GOGA5_MOUSE
NC score	0.057464 (rank : 161)	θ value	0.365318 (rank : 75)
Query Neighborhood Hits	202	Target Neighborhood Hits	1434	Shared Neighborhood Hits	66
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

CROCC_HUMAN
NC score	0.057172 (rank : 162)	θ value	0.62314 (rank : 86)
Query Neighborhood Hits	202	Target Neighborhood Hits	1409	Shared Neighborhood Hits	67
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

SRRM2_MOUSE
NC score	0.056582 (rank : 163)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	202	Target Neighborhood Hits	1470	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

RASA2_HUMAN
NC score	0.056575 (rank : 164)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	202	Target Neighborhood Hits	157	Shared Neighborhood Hits	32
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

BSN_MOUSE
NC score	0.056227 (rank : 165)	θ value	8.99809 (rank : 190)
Query Neighborhood Hits	202	Target Neighborhood Hits	2057	Shared Neighborhood Hits	99
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

DDEF2_HUMAN
NC score	0.055953 (rank : 166)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	202	Target Neighborhood Hits	599	Shared Neighborhood Hits	49
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

PRRT3_HUMAN
NC score	0.055933 (rank : 167)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	202	Target Neighborhood Hits	998	Shared Neighborhood Hits	57
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

BSN_HUMAN
NC score	0.055869 (rank : 168)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	202	Target Neighborhood Hits	1537	Shared Neighborhood Hits	93
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

DDEF2_MOUSE
NC score	0.055719 (rank : 169)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	202	Target Neighborhood Hits	625	Shared Neighborhood Hits	48
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

SFPQ_HUMAN
NC score	0.055272 (rank : 170)	θ value	2.36792 (rank : 125)
Query Neighborhood Hits	202	Target Neighborhood Hits	986	Shared Neighborhood Hits	63
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

TIAM1_MOUSE
NC score	0.054782 (rank : 171)	θ value	8.99809 (rank : 200)
Query Neighborhood Hits	202	Target Neighborhood Hits	205	Shared Neighborhood Hits	25
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

PREX1_HUMAN
NC score	0.054693 (rank : 172)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	202	Target Neighborhood Hits	177	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

SI1L3_HUMAN
NC score	0.054677 (rank : 173)	θ value	0.0736092 (rank : 57)
Query Neighborhood Hits	202	Target Neighborhood Hits	305	Shared Neighborhood Hits	28
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

ECT2_MOUSE
NC score	0.054519 (rank : 174)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	202	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

LMO7_HUMAN
NC score	0.054430 (rank : 175)	θ value	0.47712 (rank : 83)
Query Neighborhood Hits	202	Target Neighborhood Hits	507	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

MUC7_HUMAN
NC score	0.053627 (rank : 176)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	202	Target Neighborhood Hits	538	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

GA2L2_MOUSE
NC score	0.053412 (rank : 177)	θ value	0.125558 (rank : 61)
Query Neighborhood Hits	202	Target Neighborhood Hits	395	Shared Neighborhood Hits	34
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

SC24C_HUMAN
NC score	0.052988 (rank : 178)	θ value	0.365318 (rank : 79)
Query Neighborhood Hits	202	Target Neighborhood Hits	662	Shared Neighborhood Hits	32
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SYN1_HUMAN
NC score	0.052927 (rank : 179)	θ value	4.03905 (rank : 152)
Query Neighborhood Hits	202	Target Neighborhood Hits	419	Shared Neighborhood Hits	50
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

NFH_MOUSE
NC score	0.052922 (rank : 180)	θ value	5.27518 (rank : 162)
Query Neighborhood Hits	202	Target Neighborhood Hits	2247	Shared Neighborhood Hits	100
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ECT2_HUMAN
NC score	0.052749 (rank : 181)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	202	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

CI079_HUMAN
NC score	0.052541 (rank : 182)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	202	Target Neighborhood Hits	288	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

ARHGF_HUMAN
NC score	0.051850 (rank : 183)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	202	Target Neighborhood Hits	214	Shared Neighborhood Hits	34
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

NCOA6_MOUSE
NC score	0.051463 (rank : 184)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	202	Target Neighborhood Hits	1076	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

SFPQ_MOUSE
NC score	0.051378 (rank : 185)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	202	Target Neighborhood Hits	958	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

OSB11_MOUSE
NC score	0.051350 (rank : 186)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	202	Target Neighborhood Hits	71	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

NPBL_MOUSE
NC score	0.051226 (rank : 187)	θ value	4.03905 (rank : 145)
Query Neighborhood Hits	202	Target Neighborhood Hits	1041	Shared Neighborhood Hits	42
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

LIPA2_MOUSE
NC score	0.051175 (rank : 188)	θ value	0.365318 (rank : 76)
Query Neighborhood Hits	202	Target Neighborhood Hits	1282	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

WASL_MOUSE
NC score	0.050802 (rank : 189)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	202	Target Neighborhood Hits	339	Shared Neighborhood Hits	38
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

OSB11_HUMAN
NC score	0.050748 (rank : 190)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	202	Target Neighborhood Hits	60	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

SMP1L_HUMAN
NC score	0.050524 (rank : 191)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	202	Target Neighborhood Hits	74	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

CRTC1_HUMAN
NC score	0.050432 (rank : 192)	θ value	0.813845 (rank : 91)
Query Neighborhood Hits	202	Target Neighborhood Hits	319	Shared Neighborhood Hits	27
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

SMAP1_MOUSE
NC score	0.050376 (rank : 193)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	202	Target Neighborhood Hits	120	Shared Neighborhood Hits	13
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

RHG26_HUMAN
NC score	0.050334 (rank : 194)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	202	Target Neighborhood Hits	281	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

FYCO1_HUMAN
NC score	0.050285 (rank : 195)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	202	Target Neighborhood Hits	1149	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

RBP1_HUMAN
NC score	0.050141 (rank : 196)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	202	Target Neighborhood Hits	521	Shared Neighborhood Hits	35
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

MAGE1_HUMAN
NC score	0.049259 (rank : 197)	θ value	0.0563607 (rank : 53)
Query Neighborhood Hits	202	Target Neighborhood Hits	1389	Shared Neighborhood Hits	70
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

GOGA5_HUMAN
NC score	0.049062 (rank : 198)	θ value	3.0926 (rank : 134)
Query Neighborhood Hits	202	Target Neighborhood Hits	1168	Shared Neighborhood Hits	58
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

STXB4_HUMAN
NC score	0.048958 (rank : 199)	θ value	0.279714 (rank : 72)
Query Neighborhood Hits	202	Target Neighborhood Hits	616	Shared Neighborhood Hits	33
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

PCNT_HUMAN
NC score	0.048606 (rank : 200)	θ value	2.36792 (rank : 122)
Query Neighborhood Hits	202	Target Neighborhood Hits	1551	Shared Neighborhood Hits	68
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

SON_HUMAN
NC score	0.046243 (rank : 201)	θ value	1.06291 (rank : 98)
Query Neighborhood Hits	202	Target Neighborhood Hits	1568	Shared Neighborhood Hits	70
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

CP250_MOUSE
NC score	0.045939 (rank : 202)	θ value	3.0926 (rank : 130)
Query Neighborhood Hits	202	Target Neighborhood Hits	1583	Shared Neighborhood Hits	65
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

LIPA1_HUMAN
NC score	0.044070 (rank : 203)	θ value	0.62314 (rank : 88)
Query Neighborhood Hits	202	Target Neighborhood Hits	1294	Shared Neighborhood Hits	53
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

TPR_HUMAN
NC score	0.043839 (rank : 204)	θ value	1.81305 (rank : 117)
Query Neighborhood Hits	202	Target Neighborhood Hits	1921	Shared Neighborhood Hits	78
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

SYN1_MOUSE
NC score	0.043629 (rank : 205)	θ value	5.27518 (rank : 169)
Query Neighborhood Hits	202	Target Neighborhood Hits	363	Shared Neighborhood Hits	39
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

USF2_MOUSE
NC score	0.043463 (rank : 206)	θ value	0.813845 (rank : 96)
Query Neighborhood Hits	202	Target Neighborhood Hits	173	Shared Neighborhood Hits	7
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

GLE1_HUMAN
NC score	0.043439 (rank : 207)	θ value	1.81305 (rank : 114)
Query Neighborhood Hits	202	Target Neighborhood Hits	445	Shared Neighborhood Hits	27
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

SNPC4_HUMAN
NC score	0.042914 (rank : 208)	θ value	2.36792 (rank : 126)
Query Neighborhood Hits	202	Target Neighborhood Hits	589	Shared Neighborhood Hits	40
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

MLL3_HUMAN
NC score	0.042864 (rank : 209)	θ value	0.365318 (rank : 77)
Query Neighborhood Hits	202	Target Neighborhood Hits	1644	Shared Neighborhood Hits	64
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

SAPS1_HUMAN
NC score	0.042511 (rank : 210)	θ value	8.99809 (rank : 197)
Query Neighborhood Hits	202	Target Neighborhood Hits	704	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

USF2_HUMAN
NC score	0.042255 (rank : 211)	θ value	0.813845 (rank : 95)
Query Neighborhood Hits	202	Target Neighborhood Hits	155	Shared Neighborhood Hits	5
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

RHG09_HUMAN
NC score	0.041647 (rank : 212)	θ value	8.99809 (rank : 196)
Query Neighborhood Hits	202	Target Neighborhood Hits	186	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

CENPF_HUMAN
NC score	0.041551 (rank : 213)	θ value	2.36792 (rank : 119)
Query Neighborhood Hits	202	Target Neighborhood Hits	1932	Shared Neighborhood Hits	69
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

ZNHI4_HUMAN
NC score	0.040492 (rank : 214)	θ value	6.88961 (rank : 187)
Query Neighborhood Hits	202	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q9C086	Gene names	ZNHIT4, HMGA1L4, PAPA1
Domain Architecture	No domain graphic available
Description	Zinc finger HIT domain-containing protein 4 (PAP-1-associated protein 1) (PAPA-1) (High mobility group AT-hook 1-like 4).

CING_MOUSE
NC score	0.040314 (rank : 215)	θ value	6.88961 (rank : 174)
Query Neighborhood Hits	202	Target Neighborhood Hits	1432	Shared Neighborhood Hits	55
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

ANK2_HUMAN
NC score	0.038940 (rank : 216)	θ value	0.365318 (rank : 74)
Query Neighborhood Hits	202	Target Neighborhood Hits	1615	Shared Neighborhood Hits	71
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

GOGA4_MOUSE
NC score	0.038597 (rank : 217)	θ value	6.88961 (rank : 177)
Query Neighborhood Hits	202	Target Neighborhood Hits	1939	Shared Neighborhood Hits	65
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

JADE2_MOUSE
NC score	0.037984 (rank : 218)	θ value	0.125558 (rank : 62)
Query Neighborhood Hits	202	Target Neighborhood Hits	560	Shared Neighborhood Hits	32
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

MYO15_HUMAN
NC score	0.037447 (rank : 219)	θ value	1.38821 (rank : 106)
Query Neighborhood Hits	202	Target Neighborhood Hits	671	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

ATX2_MOUSE
NC score	0.037177 (rank : 220)	θ value	2.36792 (rank : 118)
Query Neighborhood Hits	202	Target Neighborhood Hits	445	Shared Neighborhood Hits	32
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

MYO9B_HUMAN
NC score	0.036811 (rank : 221)	θ value	6.88961 (rank : 180)
Query Neighborhood Hits	202	Target Neighborhood Hits	641	Shared Neighborhood Hits	37
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

T22D4_HUMAN
NC score	0.036255 (rank : 222)	θ value	4.03905 (rank : 153)
Query Neighborhood Hits	202	Target Neighborhood Hits	403	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

PSL1_HUMAN
NC score	0.035499 (rank : 223)	θ value	8.99809 (rank : 195)
Query Neighborhood Hits	202	Target Neighborhood Hits	650	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

EP15R_MOUSE
NC score	0.035499 (rank : 224)	θ value	5.27518 (rank : 159)
Query Neighborhood Hits	202	Target Neighborhood Hits	1135	Shared Neighborhood Hits	54
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

K1219_HUMAN
NC score	0.035498 (rank : 225)	θ value	1.81305 (rank : 115)
Query Neighborhood Hits	202	Target Neighborhood Hits	85	Shared Neighborhood Hits	6
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

SELPL_MOUSE
NC score	0.033239 (rank : 226)	θ value	4.03905 (rank : 151)
Query Neighborhood Hits	202	Target Neighborhood Hits	588	Shared Neighborhood Hits	37
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

CCD96_HUMAN
NC score	0.033007 (rank : 227)	θ value	4.03905 (rank : 139)
Query Neighborhood Hits	202	Target Neighborhood Hits	595	Shared Neighborhood Hits	43
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

TSC1_HUMAN
NC score	0.032866 (rank : 228)	θ value	8.99809 (rank : 201)
Query Neighborhood Hits	202	Target Neighborhood Hits	765	Shared Neighborhood Hits	37
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

MINT_MOUSE
NC score	0.032617 (rank : 229)	θ value	5.27518 (rank : 161)
Query Neighborhood Hits	202	Target Neighborhood Hits	1514	Shared Neighborhood Hits	65
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

GRIN1_MOUSE
NC score	0.032243 (rank : 230)	θ value	6.88961 (rank : 178)
Query Neighborhood Hits	202	Target Neighborhood Hits	337	Shared Neighborhood Hits	30
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

HIP1_HUMAN
NC score	0.032059 (rank : 231)	θ value	8.99809 (rank : 192)
Query Neighborhood Hits	202	Target Neighborhood Hits	1016	Shared Neighborhood Hits	45
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

K1219_MOUSE
NC score	0.032032 (rank : 232)	θ value	4.03905 (rank : 141)
Query Neighborhood Hits	202	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BQZ4, Q80TH5, Q8BQN1	Gene names	Kiaa1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

GTSE1_MOUSE
NC score	0.031942 (rank : 233)	θ value	8.99809 (rank : 191)
Query Neighborhood Hits	202	Target Neighborhood Hits	245	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

NIPA_MOUSE
NC score	0.031801 (rank : 234)	θ value	1.38821 (rank : 107)
Query Neighborhood Hits	202	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q80YV2, Q3TJE6, Q80Z11, Q8BTW5, Q8CI56, Q8R3U7	Gene names	Zc3hc1, Nipa
Domain Architecture	No domain graphic available
Description	Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (mNIPA) (Zinc finger C3HC-type protein 1).

IWS1_MOUSE
NC score	0.031237 (rank : 235)	θ value	3.0926 (rank : 136)
Query Neighborhood Hits	202	Target Neighborhood Hits	1258	Shared Neighborhood Hits	49
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CUTL2_MOUSE
NC score	0.031002 (rank : 236)	θ value	6.88961 (rank : 175)
Query Neighborhood Hits	202	Target Neighborhood Hits	771	Shared Neighborhood Hits	47
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

SPTN2_HUMAN
NC score	0.030234 (rank : 237)	θ value	5.27518 (rank : 168)
Query Neighborhood Hits	202	Target Neighborhood Hits	535	Shared Neighborhood Hits	42
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

LIPB1_HUMAN
NC score	0.029827 (rank : 238)	θ value	8.99809 (rank : 194)
Query Neighborhood Hits	202	Target Neighborhood Hits	640	Shared Neighborhood Hits	36
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

ANR15_HUMAN
NC score	0.029556 (rank : 239)	θ value	8.99809 (rank : 188)
Query Neighborhood Hits	202	Target Neighborhood Hits	478	Shared Neighborhood Hits	25
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

BAZ2B_HUMAN
NC score	0.029057 (rank : 240)	θ value	8.99809 (rank : 189)
Query Neighborhood Hits	202	Target Neighborhood Hits	803	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

DNMT1_HUMAN
NC score	0.028534 (rank : 241)	θ value	3.0926 (rank : 132)
Query Neighborhood Hits	202	Target Neighborhood Hits	401	Shared Neighborhood Hits	24
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

NHS_HUMAN
NC score	0.027417 (rank : 242)	θ value	5.27518 (rank : 163)
Query Neighborhood Hits	202	Target Neighborhood Hits	198	Shared Neighborhood Hits	14
SwissProt Accessions	Q6T4R5, Q5J7Q0, Q5J7Q1, Q68DR5	Gene names	NHS
Domain Architecture	No domain graphic available
Description	Nance-Horan syndrome protein (Congenital cataracts and dental anomalies protein).

AIM1_HUMAN
NC score	0.026645 (rank : 243)	θ value	4.03905 (rank : 138)
Query Neighborhood Hits	202	Target Neighborhood Hits	247	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

CIC_HUMAN
NC score	0.026563 (rank : 244)	θ value	6.88961 (rank : 173)
Query Neighborhood Hits	202	Target Neighborhood Hits	992	Shared Neighborhood Hits	56
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

RTN2_HUMAN
NC score	0.026217 (rank : 245)	θ value	1.38821 (rank : 110)
Query Neighborhood Hits	202	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	O75298, O60509, Q7RTM6, Q7RTN1, Q7RTN2	Gene names	RTN2, NSPL1
Domain Architecture
Description	Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (NSPLI).

FA13C_MOUSE
NC score	0.025585 (rank : 246)	θ value	1.38821 (rank : 101)
Query Neighborhood Hits	202	Target Neighborhood Hits	79	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

LAMA3_HUMAN
NC score	0.025200 (rank : 247)	θ value	1.38821 (rank : 105)
Query Neighborhood Hits	202	Target Neighborhood Hits	760	Shared Neighborhood Hits	30
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

CJ012_HUMAN
NC score	0.024716 (rank : 248)	θ value	5.27518 (rank : 158)
Query Neighborhood Hits	202	Target Neighborhood Hits	467	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

K1C16_HUMAN
NC score	0.024614 (rank : 249)	θ value	1.81305 (rank : 116)
Query Neighborhood Hits	202	Target Neighborhood Hits	440	Shared Neighborhood Hits	33
SwissProt Accessions	P08779, P30654, Q16402, Q9UBG8	Gene names	KRT16, KRT16A
Domain Architecture
Description	Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16).

PHLPP_MOUSE
NC score	0.024513 (rank : 250)	θ value	1.38821 (rank : 108)
Query Neighborhood Hits	202	Target Neighborhood Hits	394	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

KCNQ4_HUMAN
NC score	0.024376 (rank : 251)	θ value	4.03905 (rank : 143)
Query Neighborhood Hits	202	Target Neighborhood Hits	136	Shared Neighborhood Hits	7
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

PHLPP_HUMAN
NC score	0.024371 (rank : 252)	θ value	2.36792 (rank : 124)
Query Neighborhood Hits	202	Target Neighborhood Hits	604	Shared Neighborhood Hits	31
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

FHOD1_HUMAN
NC score	0.023450 (rank : 253)	θ value	2.36792 (rank : 120)
Query Neighborhood Hits	202	Target Neighborhood Hits	184	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

SI1L2_MOUSE
NC score	0.023332 (rank : 254)	θ value	5.27518 (rank : 167)
Query Neighborhood Hits	202	Target Neighborhood Hits	124	Shared Neighborhood Hits	7
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

IF4G1_HUMAN
NC score	0.023331 (rank : 255)	θ value	8.99809 (rank : 193)
Query Neighborhood Hits	202	Target Neighborhood Hits	347	Shared Neighborhood Hits	32
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

PTPR2_MOUSE
NC score	0.022560 (rank : 256)	θ value	1.38821 (rank : 109)
Query Neighborhood Hits	202	Target Neighborhood Hits	120	Shared Neighborhood Hits	3
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PERI_MOUSE
NC score	0.022218 (rank : 257)	θ value	4.03905 (rank : 147)
Query Neighborhood Hits	202	Target Neighborhood Hits	502	Shared Neighborhood Hits	34
SwissProt Accessions	P15331, O35688, O35689	Gene names	Prph, Prph1
Domain Architecture
Description	Peripherin.

PERI_HUMAN
NC score	0.020876 (rank : 258)	θ value	4.03905 (rank : 146)
Query Neighborhood Hits	202	Target Neighborhood Hits	506	Shared Neighborhood Hits	34
SwissProt Accessions	P41219, Q8N577	Gene names	PRPH
Domain Architecture
Description	Peripherin.

UBP42_HUMAN
NC score	0.020730 (rank : 259)	θ value	4.03905 (rank : 156)
Query Neighborhood Hits	202	Target Neighborhood Hits	445	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

KCNQ5_HUMAN
NC score	0.020675 (rank : 260)	θ value	1.38821 (rank : 104)
Query Neighborhood Hits	202	Target Neighborhood Hits	163	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

TBCD1_HUMAN
NC score	0.020297 (rank : 261)	θ value	4.03905 (rank : 154)
Query Neighborhood Hits	202	Target Neighborhood Hits	276	Shared Neighborhood Hits	17
SwissProt Accessions	Q86TI0, Q96K82, Q9UPP4	Gene names	TBC1D1, KIAA1108
Domain Architecture
Description	TBC1 domain family member 1.

LAMA3_MOUSE
NC score	0.019365 (rank : 262)	θ value	0.813845 (rank : 92)
Query Neighborhood Hits	202	Target Neighborhood Hits	859	Shared Neighborhood Hits	25
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

IL17B_HUMAN
NC score	0.019070 (rank : 263)	θ value	5.27518 (rank : 160)
Query Neighborhood Hits	202	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UHF5	Gene names	IL17B, IL20, NIRF, ZCYTO7
Domain Architecture
Description	Interleukin-17B precursor (IL-17B) (Cytokine-like protein Zcyto7) (Neuronal interleukin-17-related factor) (Interleukin-20) (IL-20).

RP3A_MOUSE
NC score	0.018847 (rank : 264)	θ value	5.27518 (rank : 166)
Query Neighborhood Hits	202	Target Neighborhood Hits	510	Shared Neighborhood Hits	35
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

KCNQ1_MOUSE
NC score	0.018150 (rank : 265)	θ value	4.03905 (rank : 142)
Query Neighborhood Hits	202	Target Neighborhood Hits	175	Shared Neighborhood Hits	11
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

TRI39_HUMAN
NC score	0.017963 (rank : 266)	θ value	0.365318 (rank : 80)
Query Neighborhood Hits	202	Target Neighborhood Hits	693	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

K1C12_MOUSE
NC score	0.016356 (rank : 267)	θ value	3.0926 (rank : 137)
Query Neighborhood Hits	202	Target Neighborhood Hits	409	Shared Neighborhood Hits	22
SwissProt Accessions	Q64291	Gene names	Krt12, Krt1-12, Krt1.12
Domain Architecture
Description	Keratin, type I cytoskeletal 12 (Cytokeratin-12) (CK-12) (Keratin-12) (K12).

TRI39_MOUSE
NC score	0.016164 (rank : 268)	θ value	1.38821 (rank : 111)
Query Neighborhood Hits	202	Target Neighborhood Hits	691	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

MRCKB_MOUSE
NC score	0.015735 (rank : 269)	θ value	2.36792 (rank : 121)
Query Neighborhood Hits	202	Target Neighborhood Hits	2180	Shared Neighborhood Hits	63
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MAGL2_HUMAN
NC score	0.015718 (rank : 270)	θ value	4.03905 (rank : 144)
Query Neighborhood Hits	202	Target Neighborhood Hits	69	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UJ55	Gene names	MAGEL2, NDNL1
Domain Architecture
Description	MAGE-like protein 2 (Necdin-like protein 1) (Protein nM15).

SPEG_MOUSE
NC score	0.013996 (rank : 271)	θ value	0.21417 (rank : 68)
Query Neighborhood Hits	202	Target Neighborhood Hits	1959	Shared Neighborhood Hits	66
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

FOXE2_HUMAN
NC score	0.013307 (rank : 272)	θ value	1.38821 (rank : 102)
Query Neighborhood Hits	202	Target Neighborhood Hits	236	Shared Neighborhood Hits	13
SwissProt Accessions	Q99526	Gene names	FOXE2
Domain Architecture
Description	Forkhead box protein E2 (HNF-3/fork head-like protein 5) (HFKL5) (HFKH4).

PJA1_HUMAN
NC score	0.012682 (rank : 273)	θ value	6.88961 (rank : 181)
Query Neighborhood Hits	202	Target Neighborhood Hits	159	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

STAT6_HUMAN
NC score	0.011987 (rank : 274)	θ value	8.99809 (rank : 198)
Query Neighborhood Hits	202	Target Neighborhood Hits	132	Shared Neighborhood Hits	7
SwissProt Accessions	P42226	Gene names	STAT6
Domain Architecture
Description	Signal transducer and activator of transcription 6 (IL-4 Stat).

PCDA2_HUMAN
NC score	0.011473 (rank : 275)	θ value	0.0736092 (rank : 56)
Query Neighborhood Hits	202	Target Neighborhood Hits	192	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y5H9, O75287, Q9BTV3	Gene names	PCDHA2
Domain Architecture
Description	Protocadherin alpha 2 precursor (PCDH-alpha2).

TTF2_MOUSE
NC score	0.010421 (rank : 276)	θ value	6.88961 (rank : 184)
Query Neighborhood Hits	202	Target Neighborhood Hits	364	Shared Neighborhood Hits	13
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

HIF1A_MOUSE
NC score	0.009761 (rank : 277)	θ value	3.0926 (rank : 135)
Query Neighborhood Hits	202	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8	Gene names	Hif1a
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).

ZAN_MOUSE
NC score	0.007141 (rank : 278)	θ value	8.99809 (rank : 202)
Query Neighborhood Hits	202	Target Neighborhood Hits	808	Shared Neighborhood Hits	15
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ZN409_HUMAN
NC score	0.007118 (rank : 279)	θ value	5.27518 (rank : 171)
Query Neighborhood Hits	202	Target Neighborhood Hits	842	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

HXA3_MOUSE
NC score	0.006181 (rank : 280)	θ value	4.03905 (rank : 140)
Query Neighborhood Hits	202	Target Neighborhood Hits	558	Shared Neighborhood Hits	25
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

HCN1_HUMAN
NC score	0.005892 (rank : 281)	θ value	6.88961 (rank : 179)
Query Neighborhood Hits	202	Target Neighborhood Hits	120	Shared Neighborhood Hits	9
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

WNK2_HUMAN
NC score	0.005876 (rank : 282)	θ value	6.88961 (rank : 186)
Query Neighborhood Hits	202	Target Neighborhood Hits	1407	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

RPKL1_HUMAN
NC score	0.002028 (rank : 283)	θ value	6.88961 (rank : 183)
Query Neighborhood Hits	202	Target Neighborhood Hits	708	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6S9, Q69YT9, Q6ZMQ6, Q96NR9, Q9BSU9	Gene names	RPS6KL1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

ULK1_HUMAN
NC score	0.001563 (rank : 284)	θ value	5.27518 (rank : 170)
Query Neighborhood Hits	202	Target Neighborhood Hits	1121	Shared Neighborhood Hits	30
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

ULK1_MOUSE
NC score	0.000489 (rank : 285)	θ value	6.88961 (rank : 185)
Query Neighborhood Hits	202	Target Neighborhood Hits	1214	Shared Neighborhood Hits	34
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

NPFF2_HUMAN
NC score	-0.003437 (rank : 286)	θ value	5.27518 (rank : 164)
Query Neighborhood Hits	202	Target Neighborhood Hits	804	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5X5, Q96RV1, Q9NR49	Gene names	NPFFR2, GPR74, NPFF2, NPGPR
Domain Architecture
Description	Neuropeptide FF receptor 2 (Neuropeptide G-protein coupled receptor) (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77).