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Network neighborhood for query Sequence : DYN1_MOUSE

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DYN1_MOUSE
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DYN1_HUMAN
θ value	0 (rank : 1)	NC score	0.993902 (rank : 2)
Query Neighborhood Hits	168	Target Neighborhood Hits	216	Shared Neighborhood Hits	155
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

DYN1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	168	Target Neighborhood Hits	168	Shared Neighborhood Hits	168
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

DYN2_HUMAN
θ value	0 (rank : 3)	NC score	0.981951 (rank : 3)
Query Neighborhood Hits	168	Target Neighborhood Hits	112	Shared Neighborhood Hits	57
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

DYN2_MOUSE
θ value	0 (rank : 4)	NC score	0.980376 (rank : 4)
Query Neighborhood Hits	168	Target Neighborhood Hits	104	Shared Neighborhood Hits	50
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

DYN3_HUMAN
θ value	0 (rank : 5)	NC score	0.980064 (rank : 5)
Query Neighborhood Hits	168	Target Neighborhood Hits	158	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

DNM1L_HUMAN
θ value	1.20984e-129 (rank : 6)	NC score	0.944844 (rank : 7)
Query Neighborhood Hits	168	Target Neighborhood Hits	39	Shared Neighborhood Hits	14
SwissProt Accessions	O00429, O14541, O60709, Q7L6B3, Q8TBT7, Q9BWM1, Q9Y5J2	Gene names	DNM1L, DLP1, DRP1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-like protein) (Dnm1p/Vps1p-like protein) (DVLP) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-related protein 1) (Dynamin-like protein 4) (Dynamin-like protein IV) (HdynIV).

DNM1L_MOUSE
θ value	6.00439e-129 (rank : 7)	NC score	0.945051 (rank : 6)
Query Neighborhood Hits	168	Target Neighborhood Hits	28	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K1M6, Q8BNQ5, Q8BQ64, Q8CGD0, Q8K1A1	Gene names	Dnm1l, Drp1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-related protein 1) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple).

MX1_HUMAN
θ value	4.84666e-62 (rank : 8)	NC score	0.862047 (rank : 8)
Query Neighborhood Hits	168	Target Neighborhood Hits	62	Shared Neighborhood Hits	17
SwissProt Accessions	P20591	Gene names	MX1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Interferon-regulated resistance GTP-binding protein MxA) (Interferon-induced protein p78) (IFI-78K).

MX2_MOUSE
θ value	3.14151e-61 (rank : 9)	NC score	0.860214 (rank : 9)
Query Neighborhood Hits	168	Target Neighborhood Hits	62	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WVP9, Q922L4	Gene names	Mx2
Domain Architecture	No domain graphic available
Description	Interferon-induced GTP-binding protein Mx2.

MX1_MOUSE
θ value	1.90589e-58 (rank : 10)	NC score	0.859960 (rank : 10)
Query Neighborhood Hits	168	Target Neighborhood Hits	60	Shared Neighborhood Hits	17
SwissProt Accessions	P09922	Gene names	Mx1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Influenza resistance protein).

MX2_HUMAN
θ value	1.97229e-55 (rank : 11)	NC score	0.854048 (rank : 11)
Query Neighborhood Hits	168	Target Neighborhood Hits	71	Shared Neighborhood Hits	18
SwissProt Accessions	P20592	Gene names	MX2
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx2 (Interferon-regulated resistance GTP-binding protein MxB) (p78-related protein).

OPA1_HUMAN
θ value	2.59989e-23 (rank : 12)	NC score	0.686077 (rank : 13)
Query Neighborhood Hits	168	Target Neighborhood Hits	85	Shared Neighborhood Hits	19
SwissProt Accessions	O60313	Gene names	OPA1, KIAA0567
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1) [Contains: Dynamin-like 120 kDa protein, form S1].

OPA1_MOUSE
θ value	2.59989e-23 (rank : 13)	NC score	0.688954 (rank : 12)
Query Neighborhood Hits	168	Target Neighborhood Hits	79	Shared Neighborhood Hits	19
SwissProt Accessions	P58281, Q3ULA5, Q8BKU7, Q8BLL3, Q8BM08, Q8R3J7	Gene names	Opa1
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1 homolog) (Large GTP-binding protein) (LargeG) [Contains: Dynamin-like 120 kDa protein, form S1].

CEL_HUMAN
θ value	4.92598e-06 (rank : 14)	NC score	0.075218 (rank : 33)
Query Neighborhood Hits	168	Target Neighborhood Hits	896	Shared Neighborhood Hits	61
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CYH1_HUMAN
θ value	0.00134147 (rank : 15)	NC score	0.132221 (rank : 17)
Query Neighborhood Hits	168	Target Neighborhood Hits	184	Shared Neighborhood Hits	32
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH1_MOUSE
θ value	0.00134147 (rank : 16)	NC score	0.131527 (rank : 18)
Query Neighborhood Hits	168	Target Neighborhood Hits	176	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH3_HUMAN
θ value	0.0148317 (rank : 17)	NC score	0.129425 (rank : 19)
Query Neighborhood Hits	168	Target Neighborhood Hits	137	Shared Neighborhood Hits	29
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH2_HUMAN
θ value	0.0252991 (rank : 18)	NC score	0.123307 (rank : 21)
Query Neighborhood Hits	168	Target Neighborhood Hits	175	Shared Neighborhood Hits	29
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
θ value	0.0252991 (rank : 19)	NC score	0.123177 (rank : 22)
Query Neighborhood Hits	168	Target Neighborhood Hits	171	Shared Neighborhood Hits	28
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH3_MOUSE
θ value	0.0252991 (rank : 20)	NC score	0.126472 (rank : 20)
Query Neighborhood Hits	168	Target Neighborhood Hits	148	Shared Neighborhood Hits	30
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

CNKR1_HUMAN
θ value	0.0330416 (rank : 21)	NC score	0.152735 (rank : 14)
Query Neighborhood Hits	168	Target Neighborhood Hits	154	Shared Neighborhood Hits	39
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

BCL9_HUMAN
θ value	0.0431538 (rank : 22)	NC score	0.074916 (rank : 34)
Query Neighborhood Hits	168	Target Neighborhood Hits	1008	Shared Neighborhood Hits	69
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

HXB3_HUMAN
θ value	0.0431538 (rank : 23)	NC score	0.016735 (rank : 135)
Query Neighborhood Hits	168	Target Neighborhood Hits	559	Shared Neighborhood Hits	25
SwissProt Accessions	P14651, O95615, P17484	Gene names	HOXB3, HOX2G
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7).

CNKR2_HUMAN
θ value	0.0736092 (rank : 24)	NC score	0.133502 (rank : 15)
Query Neighborhood Hits	168	Target Neighborhood Hits	197	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	0.0736092 (rank : 25)	NC score	0.133383 (rank : 16)
Query Neighborhood Hits	168	Target Neighborhood Hits	197	Shared Neighborhood Hits	30
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

OGFR_HUMAN
θ value	0.0736092 (rank : 26)	NC score	0.082812 (rank : 28)
Query Neighborhood Hits	168	Target Neighborhood Hits	1582	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

ROCK1_MOUSE
θ value	0.0736092 (rank : 27)	NC score	0.017397 (rank : 129)
Query Neighborhood Hits	168	Target Neighborhood Hits	2126	Shared Neighborhood Hits	53
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

SLK_MOUSE
θ value	0.0736092 (rank : 28)	NC score	0.011522 (rank : 153)
Query Neighborhood Hits	168	Target Neighborhood Hits	1798	Shared Neighborhood Hits	44
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

AATK_HUMAN
θ value	0.0961366 (rank : 29)	NC score	0.016852 (rank : 133)
Query Neighborhood Hits	168	Target Neighborhood Hits	1243	Shared Neighborhood Hits	52
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

CE016_HUMAN
θ value	0.0961366 (rank : 30)	NC score	0.054477 (rank : 53)
Query Neighborhood Hits	168	Target Neighborhood Hits	80	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NC24, Q6P4E7, Q6UXY2	Gene names	C5orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf16.

EPN2_HUMAN
θ value	0.0961366 (rank : 31)	NC score	0.049006 (rank : 61)
Query Neighborhood Hits	168	Target Neighborhood Hits	156	Shared Neighborhood Hits	21
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

MRIP_MOUSE
θ value	0.0961366 (rank : 32)	NC score	0.077285 (rank : 31)
Query Neighborhood Hits	168	Target Neighborhood Hits	569	Shared Neighborhood Hits	52
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

ROCK1_HUMAN
θ value	0.0961366 (rank : 33)	NC score	0.017691 (rank : 127)
Query Neighborhood Hits	168	Target Neighborhood Hits	2000	Shared Neighborhood Hits	50
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

TLE1_MOUSE
θ value	0.0961366 (rank : 34)	NC score	0.036008 (rank : 80)
Query Neighborhood Hits	168	Target Neighborhood Hits	491	Shared Neighborhood Hits	25
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

TLE4_HUMAN
θ value	0.125558 (rank : 35)	NC score	0.034229 (rank : 87)
Query Neighborhood Hits	168	Target Neighborhood Hits	477	Shared Neighborhood Hits	19
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

TLE4_MOUSE
θ value	0.125558 (rank : 36)	NC score	0.034216 (rank : 88)
Query Neighborhood Hits	168	Target Neighborhood Hits	482	Shared Neighborhood Hits	19
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

AKAP2_HUMAN
θ value	0.163984 (rank : 37)	NC score	0.040829 (rank : 69)
Query Neighborhood Hits	168	Target Neighborhood Hits	507	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

IF4B_HUMAN
θ value	0.163984 (rank : 38)	NC score	0.062236 (rank : 43)
Query Neighborhood Hits	168	Target Neighborhood Hits	417	Shared Neighborhood Hits	22
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

JPH2_HUMAN
θ value	0.163984 (rank : 39)	NC score	0.038501 (rank : 72)
Query Neighborhood Hits	168	Target Neighborhood Hits	639	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

SC24A_MOUSE
θ value	0.163984 (rank : 40)	NC score	0.060355 (rank : 45)
Query Neighborhood Hits	168	Target Neighborhood Hits	394	Shared Neighborhood Hits	49
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

TARA_MOUSE
θ value	0.163984 (rank : 41)	NC score	0.074331 (rank : 35)
Query Neighborhood Hits	168	Target Neighborhood Hits	1133	Shared Neighborhood Hits	78
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

DIDO1_HUMAN
θ value	0.21417 (rank : 42)	NC score	0.043014 (rank : 66)
Query Neighborhood Hits	168	Target Neighborhood Hits	960	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

MRIP_HUMAN
θ value	0.21417 (rank : 43)	NC score	0.077885 (rank : 30)
Query Neighborhood Hits	168	Target Neighborhood Hits	578	Shared Neighborhood Hits	51
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

PRRT3_HUMAN
θ value	0.21417 (rank : 44)	NC score	0.076696 (rank : 32)
Query Neighborhood Hits	168	Target Neighborhood Hits	998	Shared Neighborhood Hits	62
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SYNE2_HUMAN
θ value	0.21417 (rank : 45)	NC score	0.021272 (rank : 119)
Query Neighborhood Hits	168	Target Neighborhood Hits	1323	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

CK024_HUMAN
θ value	0.279714 (rank : 46)	NC score	0.051447 (rank : 58)
Query Neighborhood Hits	168	Target Neighborhood Hits	408	Shared Neighborhood Hits	33
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

K1802_MOUSE
θ value	0.279714 (rank : 47)	NC score	0.034629 (rank : 84)
Query Neighborhood Hits	168	Target Neighborhood Hits	1596	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

NCOA6_HUMAN
θ value	0.279714 (rank : 48)	NC score	0.059518 (rank : 46)
Query Neighborhood Hits	168	Target Neighborhood Hits	1202	Shared Neighborhood Hits	69
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

RHG25_HUMAN
θ value	0.279714 (rank : 49)	NC score	0.072024 (rank : 39)
Query Neighborhood Hits	168	Target Neighborhood Hits	550	Shared Neighborhood Hits	40
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

S23IP_MOUSE
θ value	0.279714 (rank : 50)	NC score	0.045274 (rank : 64)
Query Neighborhood Hits	168	Target Neighborhood Hits	363	Shared Neighborhood Hits	40
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

SLK_HUMAN
θ value	0.279714 (rank : 51)	NC score	0.010566 (rank : 157)
Query Neighborhood Hits	168	Target Neighborhood Hits	1775	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

MYO15_HUMAN
θ value	0.365318 (rank : 52)	NC score	0.022452 (rank : 115)
Query Neighborhood Hits	168	Target Neighborhood Hits	671	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PKHA5_HUMAN
θ value	0.365318 (rank : 53)	NC score	0.093828 (rank : 26)
Query Neighborhood Hits	168	Target Neighborhood Hits	455	Shared Neighborhood Hits	40
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

SC24C_HUMAN
θ value	0.365318 (rank : 54)	NC score	0.056768 (rank : 51)
Query Neighborhood Hits	168	Target Neighborhood Hits	662	Shared Neighborhood Hits	55
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

TLE1_HUMAN
θ value	0.365318 (rank : 55)	NC score	0.034562 (rank : 85)
Query Neighborhood Hits	168	Target Neighborhood Hits	485	Shared Neighborhood Hits	26
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

BCL9_MOUSE
θ value	0.47712 (rank : 56)	NC score	0.062335 (rank : 42)
Query Neighborhood Hits	168	Target Neighborhood Hits	770	Shared Neighborhood Hits	63
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

C2TA_HUMAN
θ value	0.47712 (rank : 57)	NC score	0.033282 (rank : 90)
Query Neighborhood Hits	168	Target Neighborhood Hits	190	Shared Neighborhood Hits	17
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

CECR2_HUMAN
θ value	0.47712 (rank : 58)	NC score	0.035393 (rank : 82)
Query Neighborhood Hits	168	Target Neighborhood Hits	543	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

EPN3_MOUSE
θ value	0.47712 (rank : 59)	NC score	0.051942 (rank : 56)
Query Neighborhood Hits	168	Target Neighborhood Hits	312	Shared Neighborhood Hits	31
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

NCOA6_MOUSE
θ value	0.47712 (rank : 60)	NC score	0.053657 (rank : 54)
Query Neighborhood Hits	168	Target Neighborhood Hits	1076	Shared Neighborhood Hits	66
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

RHG25_MOUSE
θ value	0.47712 (rank : 61)	NC score	0.073912 (rank : 36)
Query Neighborhood Hits	168	Target Neighborhood Hits	492	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RUNX1_MOUSE
θ value	0.47712 (rank : 62)	NC score	0.018117 (rank : 125)
Query Neighborhood Hits	168	Target Neighborhood Hits	93	Shared Neighborhood Hits	7
SwissProt Accessions	Q03347, O08598, Q62049, Q9ESB9, Q9ET65	Gene names	Runx1, Aml1, Cbfa2, Pebp2ab
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

IF4B_MOUSE
θ value	0.62314 (rank : 63)	NC score	0.057664 (rank : 48)
Query Neighborhood Hits	168	Target Neighborhood Hits	368	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

K1802_HUMAN
θ value	0.62314 (rank : 64)	NC score	0.034374 (rank : 86)
Query Neighborhood Hits	168	Target Neighborhood Hits	1378	Shared Neighborhood Hits	68
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

ZIMP7_HUMAN
θ value	0.62314 (rank : 65)	NC score	0.047128 (rank : 63)
Query Neighborhood Hits	168	Target Neighborhood Hits	290	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

BCAR1_MOUSE
θ value	0.813845 (rank : 66)	NC score	0.024241 (rank : 111)
Query Neighborhood Hits	168	Target Neighborhood Hits	438	Shared Neighborhood Hits	31
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

MUC1_HUMAN
θ value	0.813845 (rank : 67)	NC score	0.040516 (rank : 70)
Query Neighborhood Hits	168	Target Neighborhood Hits	975	Shared Neighborhood Hits	63
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

PELP1_MOUSE
θ value	0.813845 (rank : 68)	NC score	0.049155 (rank : 60)
Query Neighborhood Hits	168	Target Neighborhood Hits	709	Shared Neighborhood Hits	58
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

RP3A_MOUSE
θ value	0.813845 (rank : 69)	NC score	0.018716 (rank : 123)
Query Neighborhood Hits	168	Target Neighborhood Hits	510	Shared Neighborhood Hits	41
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SPEG_HUMAN
θ value	0.813845 (rank : 70)	NC score	0.012587 (rank : 150)
Query Neighborhood Hits	168	Target Neighborhood Hits	1762	Shared Neighborhood Hits	72
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

CSTF2_HUMAN
θ value	1.06291 (rank : 71)	NC score	0.019109 (rank : 121)
Query Neighborhood Hits	168	Target Neighborhood Hits	296	Shared Neighborhood Hits	14
SwissProt Accessions	P33240, Q5H951, Q6LA74, Q8N502	Gene names	CSTF2
Domain Architecture
Description	Cleavage stimulation factor 64 kDa subunit (CSTF 64 kDa subunit) (CF-1 64 kDa subunit) (CstF-64).

DESM_MOUSE
θ value	1.06291 (rank : 72)	NC score	0.010738 (rank : 155)
Query Neighborhood Hits	168	Target Neighborhood Hits	498	Shared Neighborhood Hits	21
SwissProt Accessions	P31001	Gene names	Des
Domain Architecture
Description	Desmin.

PKHB1_HUMAN
θ value	1.06291 (rank : 73)	NC score	0.078157 (rank : 29)
Query Neighborhood Hits	168	Target Neighborhood Hits	46	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UF11, Q9UBF5, Q9UI37, Q9UI44	Gene names	PLEKHB1, KPL1, PHR1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

PKHB1_MOUSE
θ value	1.06291 (rank : 74)	NC score	0.072251 (rank : 38)
Query Neighborhood Hits	168	Target Neighborhood Hits	47	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QYE9, Q9QYB3, Q9QYB4, Q9QYD2, Q9QYD3	Gene names	Plekhb1, Phr1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

PSMF1_MOUSE
θ value	1.06291 (rank : 75)	NC score	0.036521 (rank : 79)
Query Neighborhood Hits	168	Target Neighborhood Hits	85	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BHL8, Q8C0G9	Gene names	Psmf1
Domain Architecture	No domain graphic available
Description	Proteasome inhibitor PI31 subunit.

RIF1_MOUSE
θ value	1.06291 (rank : 76)	NC score	0.025411 (rank : 105)
Query Neighborhood Hits	168	Target Neighborhood Hits	315	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

ZIM10_HUMAN
θ value	1.06291 (rank : 77)	NC score	0.043707 (rank : 65)
Query Neighborhood Hits	168	Target Neighborhood Hits	577	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ANGL1_MOUSE
θ value	1.38821 (rank : 78)	NC score	0.009642 (rank : 160)
Query Neighborhood Hits	168	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	Q640P2, Q3UQL1, Q9CZ81	Gene names	Angptl1
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 1 precursor (Angiopoietin-like 1).

ASTL_HUMAN
θ value	1.38821 (rank : 79)	NC score	0.024444 (rank : 110)
Query Neighborhood Hits	168	Target Neighborhood Hits	252	Shared Neighborhood Hits	31
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

BAG4_HUMAN
θ value	1.38821 (rank : 80)	NC score	0.032841 (rank : 91)
Query Neighborhood Hits	168	Target Neighborhood Hits	96	Shared Neighborhood Hits	12
SwissProt Accessions	O95429, O95818	Gene names	BAG4, SODD
Domain Architecture
Description	BAG family molecular chaperone regulator 4 (BCL2-associated athanogene 4) (BAG-4) (Silencer of death domains).

BMX_HUMAN
θ value	1.38821 (rank : 81)	NC score	0.006526 (rank : 170)
Query Neighborhood Hits	168	Target Neighborhood Hits	942	Shared Neighborhood Hits	26
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

CSKI1_HUMAN
θ value	1.38821 (rank : 82)	NC score	0.023067 (rank : 114)
Query Neighborhood Hits	168	Target Neighborhood Hits	997	Shared Neighborhood Hits	73
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CYH4_MOUSE
θ value	1.38821 (rank : 83)	NC score	0.105342 (rank : 23)
Query Neighborhood Hits	168	Target Neighborhood Hits	134	Shared Neighborhood Hits	28
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

EGR4_HUMAN
θ value	1.38821 (rank : 84)	NC score	0.014178 (rank : 142)
Query Neighborhood Hits	168	Target Neighborhood Hits	939	Shared Neighborhood Hits	22
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

HPS4_HUMAN
θ value	1.38821 (rank : 85)	NC score	0.031274 (rank : 94)
Query Neighborhood Hits	168	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NQG7, Q5H8V6, Q96LX6, Q9BY93, Q9UH37, Q9UH38	Gene names	HPS4, KIAA1667
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 4 protein (Light-ear protein homolog).

MUCDL_HUMAN
θ value	1.38821 (rank : 86)	NC score	0.032083 (rank : 93)
Query Neighborhood Hits	168	Target Neighborhood Hits	777	Shared Neighborhood Hits	59
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NCOA3_MOUSE
θ value	1.38821 (rank : 87)	NC score	0.017082 (rank : 131)
Query Neighborhood Hits	168	Target Neighborhood Hits	203	Shared Neighborhood Hits	17
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

NFAC1_HUMAN
θ value	1.38821 (rank : 88)	NC score	0.027449 (rank : 102)
Query Neighborhood Hits	168	Target Neighborhood Hits	312	Shared Neighborhood Hits	36
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

ZN385_HUMAN
θ value	1.38821 (rank : 89)	NC score	0.025201 (rank : 108)
Query Neighborhood Hits	168	Target Neighborhood Hits	614	Shared Neighborhood Hits	36
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

CENPE_HUMAN
θ value	1.81305 (rank : 90)	NC score	0.012731 (rank : 149)
Query Neighborhood Hits	168	Target Neighborhood Hits	2060	Shared Neighborhood Hits	51
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

EPN3_HUMAN
θ value	1.81305 (rank : 91)	NC score	0.037429 (rank : 75)
Query Neighborhood Hits	168	Target Neighborhood Hits	197	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

FYCO1_HUMAN
θ value	1.81305 (rank : 92)	NC score	0.023404 (rank : 113)
Query Neighborhood Hits	168	Target Neighborhood Hits	1149	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

K2C6B_MOUSE
θ value	1.81305 (rank : 93)	NC score	0.014654 (rank : 141)
Query Neighborhood Hits	168	Target Neighborhood Hits	506	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z331	Gene names	Krt6b, K6-beta, Krt2-6b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin) (Keratin-6 beta) (mK6-beta).

MEGF9_MOUSE
θ value	1.81305 (rank : 94)	NC score	0.018651 (rank : 124)
Query Neighborhood Hits	168	Target Neighborhood Hits	896	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NRX2A_HUMAN
θ value	1.81305 (rank : 95)	NC score	0.025088 (rank : 109)
Query Neighborhood Hits	168	Target Neighborhood Hits	614	Shared Neighborhood Hits	41
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	1.81305 (rank : 96)	NC score	0.037884 (rank : 73)
Query Neighborhood Hits	168	Target Neighborhood Hits	481	Shared Neighborhood Hits	40
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

PKHA6_HUMAN
θ value	1.81305 (rank : 97)	NC score	0.098819 (rank : 25)
Query Neighborhood Hits	168	Target Neighborhood Hits	556	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

SCEL_HUMAN
θ value	1.81305 (rank : 98)	NC score	0.026183 (rank : 104)
Query Neighborhood Hits	168	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	O95171	Gene names	SCEL
Domain Architecture
Description	Sciellin.

SMRD2_MOUSE
θ value	1.81305 (rank : 99)	NC score	0.017354 (rank : 130)
Query Neighborhood Hits	168	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q99JR8	Gene names	Smarcd2, Baf60b
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 (60 kDa BRG-1/Brm-associated factor subunit B) (BRG1-associated factor 60B).

ALDR_HUMAN
θ value	2.36792 (rank : 100)	NC score	0.010599 (rank : 156)
Query Neighborhood Hits	168	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P15121, Q9BS21, Q9UCI9	Gene names	AKR1B1, ALDR1
Domain Architecture
Description	Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase).

BSN_MOUSE
θ value	2.36792 (rank : 101)	NC score	0.041033 (rank : 67)
Query Neighborhood Hits	168	Target Neighborhood Hits	2057	Shared Neighborhood Hits	98
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CO9A1_MOUSE
θ value	2.36792 (rank : 102)	NC score	0.013934 (rank : 144)
Query Neighborhood Hits	168	Target Neighborhood Hits	477	Shared Neighborhood Hits	44
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

ELOA2_HUMAN
θ value	2.36792 (rank : 103)	NC score	0.017056 (rank : 132)
Query Neighborhood Hits	168	Target Neighborhood Hits	165	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IYF1, Q9P2V9	Gene names	TCEB3B, TCEB3L
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A2 (Elongin-A2) (EloA2) (Transcription elongation factor B polypeptide 3B).

GLYG2_HUMAN
θ value	2.36792 (rank : 104)	NC score	0.024127 (rank : 112)
Query Neighborhood Hits	168	Target Neighborhood Hits	65	Shared Neighborhood Hits	8
SwissProt Accessions	O15488, O15485, O15486, O15487, O15489, O15490	Gene names	GYG2
Domain Architecture
Description	Glycogenin-2 (EC 2.4.1.186) (GN-2) (GN2).

SIM2_HUMAN
θ value	2.36792 (rank : 105)	NC score	0.008335 (rank : 164)
Query Neighborhood Hits	168	Target Neighborhood Hits	76	Shared Neighborhood Hits	7
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

COG8_MOUSE
θ value	3.0926 (rank : 106)	NC score	0.025358 (rank : 107)
Query Neighborhood Hits	168	Target Neighborhood Hits	147	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JJA2	Gene names	Cog8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

CP250_MOUSE
θ value	3.0926 (rank : 107)	NC score	0.013102 (rank : 146)
Query Neighborhood Hits	168	Target Neighborhood Hits	1583	Shared Neighborhood Hits	39
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

CYH4_HUMAN
θ value	3.0926 (rank : 108)	NC score	0.100229 (rank : 24)
Query Neighborhood Hits	168	Target Neighborhood Hits	135	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

GRAP1_MOUSE
θ value	3.0926 (rank : 109)	NC score	0.015913 (rank : 137)
Query Neighborhood Hits	168	Target Neighborhood Hits	1234	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

MLL2_HUMAN
θ value	3.0926 (rank : 110)	NC score	0.036578 (rank : 78)
Query Neighborhood Hits	168	Target Neighborhood Hits	1788	Shared Neighborhood Hits	101
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

RBCC1_MOUSE
θ value	3.0926 (rank : 111)	NC score	0.018953 (rank : 122)
Query Neighborhood Hits	168	Target Neighborhood Hits	1048	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

SPEG_MOUSE
θ value	3.0926 (rank : 112)	NC score	0.012343 (rank : 151)
Query Neighborhood Hits	168	Target Neighborhood Hits	1959	Shared Neighborhood Hits	73
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SYNP2_HUMAN
θ value	3.0926 (rank : 113)	NC score	0.022271 (rank : 116)
Query Neighborhood Hits	168	Target Neighborhood Hits	323	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

TITIN_HUMAN
θ value	3.0926 (rank : 114)	NC score	0.008651 (rank : 163)
Query Neighborhood Hits	168	Target Neighborhood Hits	2923	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

UGGG2_HUMAN
θ value	3.0926 (rank : 115)	NC score	0.013973 (rank : 143)
Query Neighborhood Hits	168	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYU1, Q9UFC4	Gene names	UGCGL2, UGT2
Domain Architecture
Description	UDP-glucose:glycoprotein glucosyltransferase 2 precursor (EC 2.4.1.-) (UDP-glucose ceramide glucosyltransferase-like 1) (UDP-- Glc:glycoprotein glucosyltransferase 2) (HUGT2).

CAC1B_HUMAN
θ value	4.03905 (rank : 116)	NC score	0.010895 (rank : 154)
Query Neighborhood Hits	168	Target Neighborhood Hits	257	Shared Neighborhood Hits	19
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CCD37_MOUSE
θ value	4.03905 (rank : 117)	NC score	0.021416 (rank : 118)
Query Neighborhood Hits	168	Target Neighborhood Hits	199	Shared Neighborhood Hits	13
SwissProt Accessions	Q80VN0, Q6AXD6	Gene names	Ccdc37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

CIC_HUMAN
θ value	4.03905 (rank : 118)	NC score	0.033868 (rank : 89)
Query Neighborhood Hits	168	Target Neighborhood Hits	992	Shared Neighborhood Hits	74
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

DESM_HUMAN
θ value	4.03905 (rank : 119)	NC score	0.008718 (rank : 162)
Query Neighborhood Hits	168	Target Neighborhood Hits	495	Shared Neighborhood Hits	22
SwissProt Accessions	P17661, Q15787, Q8IZR1, Q8IZR6, Q8NES2, Q8NEU6, Q8TAC4, Q8TCX2, Q8TD99, Q9UHN5, Q9UJ80	Gene names	DES
Domain Architecture
Description	Desmin.

GLI2_HUMAN
θ value	4.03905 (rank : 120)	NC score	0.000277 (rank : 178)
Query Neighborhood Hits	168	Target Neighborhood Hits	971	Shared Neighborhood Hits	27
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

GOGA4_HUMAN
θ value	4.03905 (rank : 121)	NC score	0.013644 (rank : 145)
Query Neighborhood Hits	168	Target Neighborhood Hits	2034	Shared Neighborhood Hits	44
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

MAML2_HUMAN
θ value	4.03905 (rank : 122)	NC score	0.028200 (rank : 98)
Query Neighborhood Hits	168	Target Neighborhood Hits	360	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

MAST1_HUMAN
θ value	4.03905 (rank : 123)	NC score	0.005917 (rank : 173)
Query Neighborhood Hits	168	Target Neighborhood Hits	1146	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MLL3_HUMAN
θ value	4.03905 (rank : 124)	NC score	0.032127 (rank : 92)
Query Neighborhood Hits	168	Target Neighborhood Hits	1644	Shared Neighborhood Hits	70
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PKHA6_MOUSE
θ value	4.03905 (rank : 125)	NC score	0.092861 (rank : 27)
Query Neighborhood Hits	168	Target Neighborhood Hits	591	Shared Neighborhood Hits	63
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

TROAP_HUMAN
θ value	4.03905 (rank : 126)	NC score	0.030767 (rank : 95)
Query Neighborhood Hits	168	Target Neighborhood Hits	258	Shared Neighborhood Hits	25
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

ZIMP7_MOUSE
θ value	4.03905 (rank : 127)	NC score	0.040209 (rank : 71)
Query Neighborhood Hits	168	Target Neighborhood Hits	566	Shared Neighborhood Hits	48
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

AMOL1_MOUSE
θ value	5.27518 (rank : 128)	NC score	0.014719 (rank : 140)
Query Neighborhood Hits	168	Target Neighborhood Hits	445	Shared Neighborhood Hits	22
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

AP3D1_MOUSE
θ value	5.27518 (rank : 129)	NC score	0.009937 (rank : 158)
Query Neighborhood Hits	168	Target Neighborhood Hits	144	Shared Neighborhood Hits	10
SwissProt Accessions	O54774	Gene names	Ap3d1, Ap3d
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin) (mBLVR1).

BMX_MOUSE
θ value	5.27518 (rank : 130)	NC score	0.005124 (rank : 174)
Query Neighborhood Hits	168	Target Neighborhood Hits	912	Shared Neighborhood Hits	25
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

CING_MOUSE
θ value	5.27518 (rank : 131)	NC score	0.012184 (rank : 152)
Query Neighborhood Hits	168	Target Neighborhood Hits	1432	Shared Neighborhood Hits	39
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CRTC1_HUMAN
θ value	5.27518 (rank : 132)	NC score	0.037099 (rank : 77)
Query Neighborhood Hits	168	Target Neighborhood Hits	319	Shared Neighborhood Hits	48
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

ICK_MOUSE
θ value	5.27518 (rank : 133)	NC score	0.003429 (rank : 175)
Query Neighborhood Hits	168	Target Neighborhood Hits	860	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JKV2, Q8K138	Gene names	Ick
Domain Architecture
Description	Serine/threonine-protein kinase ICK (EC 2.7.11.22) (Intestinal cell kinase) (mICK) (MAK-related kinase) (MRK).

IL9R_HUMAN
θ value	5.27518 (rank : 134)	NC score	0.015943 (rank : 136)
Query Neighborhood Hits	168	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q01113, Q14634, Q8WWU1, Q96TF0	Gene names	IL9R
Domain Architecture	No domain graphic available
Description	Interleukin-9 receptor precursor (IL-9R) (CD129 antigen).

KI67_HUMAN
θ value	5.27518 (rank : 135)	NC score	0.021193 (rank : 120)
Query Neighborhood Hits	168	Target Neighborhood Hits	581	Shared Neighborhood Hits	27
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

LSD1_HUMAN
θ value	5.27518 (rank : 136)	NC score	0.012950 (rank : 148)
Query Neighborhood Hits	168	Target Neighborhood Hits	455	Shared Neighborhood Hits	29
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

MFN1_HUMAN
θ value	5.27518 (rank : 137)	NC score	0.052020 (rank : 55)
Query Neighborhood Hits	168	Target Neighborhood Hits	71	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IWA4, O15323, O60639, Q9BZB5, Q9NWQ2	Gene names	MFN1
Domain Architecture
Description	Transmembrane GTPase MFN1 (EC 3.6.5.-) (Mitofusin-1) (Fzo homolog).

NACAM_MOUSE
θ value	5.27518 (rank : 138)	NC score	0.035298 (rank : 83)
Query Neighborhood Hits	168	Target Neighborhood Hits	1866	Shared Neighborhood Hits	79
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PAK4_MOUSE
θ value	5.27518 (rank : 139)	NC score	0.006770 (rank : 169)
Query Neighborhood Hits	168	Target Neighborhood Hits	1098	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

POMT2_MOUSE
θ value	5.27518 (rank : 140)	NC score	0.012972 (rank : 147)
Query Neighborhood Hits	168	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGQ4, Q8R4Z0	Gene names	Pomt2
Domain Architecture
Description	Protein O-mannosyl-transferase 2 (EC 2.4.1.109) (Dolichyl-phosphate- mannose--protein mannosyltransferase 2).

SON_HUMAN
θ value	5.27518 (rank : 141)	NC score	0.047245 (rank : 62)
Query Neighborhood Hits	168	Target Neighborhood Hits	1568	Shared Neighborhood Hits	73
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SRRM1_MOUSE
θ value	5.27518 (rank : 142)	NC score	0.037878 (rank : 74)
Query Neighborhood Hits	168	Target Neighborhood Hits	966	Shared Neighborhood Hits	59
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

ZIM10_MOUSE
θ value	5.27518 (rank : 143)	NC score	0.035593 (rank : 81)
Query Neighborhood Hits	168	Target Neighborhood Hits	430	Shared Neighborhood Hits	41
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZN516_MOUSE
θ value	5.27518 (rank : 144)	NC score	0.006257 (rank : 171)
Query Neighborhood Hits	168	Target Neighborhood Hits	1197	Shared Neighborhood Hits	40
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

AP3D1_HUMAN
θ value	6.88961 (rank : 145)	NC score	0.008830 (rank : 161)
Query Neighborhood Hits	168	Target Neighborhood Hits	254	Shared Neighborhood Hits	11
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

BIM_HUMAN
θ value	6.88961 (rank : 146)	NC score	0.017524 (rank : 128)
Query Neighborhood Hits	168	Target Neighborhood Hits	134	Shared Neighborhood Hits	8
SwissProt Accessions	O43521, O43522	Gene names	BCL2L11, BIM
Domain Architecture
Description	Bcl-2-like protein 11 (Bcl2-interacting mediator of cell death).

KCNQ4_HUMAN
θ value	6.88961 (rank : 147)	NC score	0.007154 (rank : 168)
Query Neighborhood Hits	168	Target Neighborhood Hits	136	Shared Neighborhood Hits	6
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

MAP1A_HUMAN
θ value	6.88961 (rank : 148)	NC score	0.026247 (rank : 103)
Query Neighborhood Hits	168	Target Neighborhood Hits	1626	Shared Neighborhood Hits	73
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MTSS1_MOUSE
θ value	6.88961 (rank : 149)	NC score	0.029065 (rank : 97)
Query Neighborhood Hits	168	Target Neighborhood Hits	592	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

PCLO_MOUSE
θ value	6.88961 (rank : 150)	NC score	0.028061 (rank : 99)
Query Neighborhood Hits	168	Target Neighborhood Hits	2275	Shared Neighborhood Hits	92
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RBCC1_HUMAN
θ value	6.88961 (rank : 151)	NC score	0.017797 (rank : 126)
Query Neighborhood Hits	168	Target Neighborhood Hits	1023	Shared Neighborhood Hits	29
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

RGS3_MOUSE
θ value	6.88961 (rank : 152)	NC score	0.037275 (rank : 76)
Query Neighborhood Hits	168	Target Neighborhood Hits	1621	Shared Neighborhood Hits	75
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SYNG_MOUSE
θ value	6.88961 (rank : 153)	NC score	0.015540 (rank : 138)
Query Neighborhood Hits	168	Target Neighborhood Hits	206	Shared Neighborhood Hits	17
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

TBCD1_HUMAN
θ value	6.88961 (rank : 154)	NC score	0.009890 (rank : 159)
Query Neighborhood Hits	168	Target Neighborhood Hits	276	Shared Neighborhood Hits	14
SwissProt Accessions	Q86TI0, Q96K82, Q9UPP4	Gene names	TBC1D1, KIAA1108
Domain Architecture
Description	TBC1 domain family member 1.

ZN598_HUMAN
θ value	6.88961 (rank : 155)	NC score	0.027817 (rank : 100)
Query Neighborhood Hits	168	Target Neighborhood Hits	339	Shared Neighborhood Hits	43
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

AT2A3_MOUSE
θ value	8.99809 (rank : 156)	NC score	0.002821 (rank : 177)
Query Neighborhood Hits	168	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	Q64518, O70625, Q64517	Gene names	Atp2a3
Domain Architecture
Description	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (EC 3.6.3.8) (Calcium pump 3) (SERCA3) (SR Ca(2+)-ATPase 3).

COKA1_HUMAN
θ value	8.99809 (rank : 157)	NC score	0.006201 (rank : 172)
Query Neighborhood Hits	168	Target Neighborhood Hits	403	Shared Neighborhood Hits	24
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

CRSP2_HUMAN
θ value	8.99809 (rank : 158)	NC score	0.027672 (rank : 101)
Query Neighborhood Hits	168	Target Neighborhood Hits	380	Shared Neighborhood Hits	43
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

CU086_HUMAN
θ value	8.99809 (rank : 159)	NC score	0.040874 (rank : 68)
Query Neighborhood Hits	168	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	P59089	Gene names	C21orf86
Domain Architecture	No domain graphic available
Description	Protein C21orf86.

FOG1_MOUSE
θ value	8.99809 (rank : 160)	NC score	0.007317 (rank : 166)
Query Neighborhood Hits	168	Target Neighborhood Hits	1237	Shared Neighborhood Hits	55
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

HXD3_HUMAN
θ value	8.99809 (rank : 161)	NC score	0.007280 (rank : 167)
Query Neighborhood Hits	168	Target Neighborhood Hits	433	Shared Neighborhood Hits	26
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

ICK_HUMAN
θ value	8.99809 (rank : 162)	NC score	0.002943 (rank : 176)
Query Neighborhood Hits	168	Target Neighborhood Hits	867	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UPZ9, O75985, Q5THL2, Q8IYH8, Q9BX17, Q9NYX3	Gene names	ICK, KIAA0936
Domain Architecture
Description	Serine/threonine-protein kinase ICK (EC 2.7.11.22) (Intestinal cell kinase) (hICK) (MAK-related kinase) (MRK) (Laryngeal cancer kinase 2) (LCK2).

JIP3_HUMAN
θ value	8.99809 (rank : 163)	NC score	0.016810 (rank : 134)
Query Neighborhood Hits	168	Target Neighborhood Hits	1039	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

MILK1_MOUSE
θ value	8.99809 (rank : 164)	NC score	0.022188 (rank : 117)
Query Neighborhood Hits	168	Target Neighborhood Hits	788	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

PCLO_HUMAN
θ value	8.99809 (rank : 165)	NC score	0.030423 (rank : 96)
Query Neighborhood Hits	168	Target Neighborhood Hits	2046	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PHC2_HUMAN
θ value	8.99809 (rank : 166)	NC score	0.015086 (rank : 139)
Query Neighborhood Hits	168	Target Neighborhood Hits	388	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

SAPS1_HUMAN
θ value	8.99809 (rank : 167)	NC score	0.025394 (rank : 106)
Query Neighborhood Hits	168	Target Neighborhood Hits	704	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SOX17_MOUSE
θ value	8.99809 (rank : 168)	NC score	0.007537 (rank : 165)
Query Neighborhood Hits	168	Target Neighborhood Hits	223	Shared Neighborhood Hits	25
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

CN032_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.055152 (rank : 52)
Query Neighborhood Hits	168	Target Neighborhood Hits	267	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CN032_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.051813 (rank : 57)
Query Neighborhood Hits	168	Target Neighborhood Hits	233	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

PKHA1_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.050779 (rank : 59)
Query Neighborhood Hits	168	Target Neighborhood Hits	127	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA4_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.072674 (rank : 37)
Query Neighborhood Hits	168	Target Neighborhood Hits	283	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA4_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.064017 (rank : 41)
Query Neighborhood Hits	168	Target Neighborhood Hits	202	Shared Neighborhood Hits	39
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PLEK_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.058147 (rank : 47)
Query Neighborhood Hits	168	Target Neighborhood Hits	110	Shared Neighborhood Hits	23
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PRB3_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.057400 (rank : 49)
Query Neighborhood Hits	168	Target Neighborhood Hits	318	Shared Neighborhood Hits	60
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.056809 (rank : 50)
Query Neighborhood Hits	168	Target Neighborhood Hits	330	Shared Neighborhood Hits	61
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRP1_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.061765 (rank : 44)
Query Neighborhood Hits	168	Target Neighborhood Hits	385	Shared Neighborhood Hits	69
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.069109 (rank : 40)
Query Neighborhood Hits	168	Target Neighborhood Hits	347	Shared Neighborhood Hits	76
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

Hits sorted by NC score

DYN1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	168	Target Neighborhood Hits	168	Shared Neighborhood Hits	168
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

DYN1_HUMAN
NC score	0.993902 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	168	Target Neighborhood Hits	216	Shared Neighborhood Hits	155
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

DYN2_HUMAN
NC score	0.981951 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	168	Target Neighborhood Hits	112	Shared Neighborhood Hits	57
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

DYN2_MOUSE
NC score	0.980376 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	168	Target Neighborhood Hits	104	Shared Neighborhood Hits	50
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

DYN3_HUMAN
NC score	0.980064 (rank : 5)	θ value	0 (rank : 5)
Query Neighborhood Hits	168	Target Neighborhood Hits	158	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

DNM1L_MOUSE
NC score	0.945051 (rank : 6)	θ value	6.00439e-129 (rank : 7)
Query Neighborhood Hits	168	Target Neighborhood Hits	28	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K1M6, Q8BNQ5, Q8BQ64, Q8CGD0, Q8K1A1	Gene names	Dnm1l, Drp1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-related protein 1) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple).

DNM1L_HUMAN
NC score	0.944844 (rank : 7)	θ value	1.20984e-129 (rank : 6)
Query Neighborhood Hits	168	Target Neighborhood Hits	39	Shared Neighborhood Hits	14
SwissProt Accessions	O00429, O14541, O60709, Q7L6B3, Q8TBT7, Q9BWM1, Q9Y5J2	Gene names	DNM1L, DLP1, DRP1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-like protein) (Dnm1p/Vps1p-like protein) (DVLP) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-related protein 1) (Dynamin-like protein 4) (Dynamin-like protein IV) (HdynIV).

MX1_HUMAN
NC score	0.862047 (rank : 8)	θ value	4.84666e-62 (rank : 8)
Query Neighborhood Hits	168	Target Neighborhood Hits	62	Shared Neighborhood Hits	17
SwissProt Accessions	P20591	Gene names	MX1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Interferon-regulated resistance GTP-binding protein MxA) (Interferon-induced protein p78) (IFI-78K).

MX2_MOUSE
NC score	0.860214 (rank : 9)	θ value	3.14151e-61 (rank : 9)
Query Neighborhood Hits	168	Target Neighborhood Hits	62	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WVP9, Q922L4	Gene names	Mx2
Domain Architecture	No domain graphic available
Description	Interferon-induced GTP-binding protein Mx2.

MX1_MOUSE
NC score	0.859960 (rank : 10)	θ value	1.90589e-58 (rank : 10)
Query Neighborhood Hits	168	Target Neighborhood Hits	60	Shared Neighborhood Hits	17
SwissProt Accessions	P09922	Gene names	Mx1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Influenza resistance protein).

MX2_HUMAN
NC score	0.854048 (rank : 11)	θ value	1.97229e-55 (rank : 11)
Query Neighborhood Hits	168	Target Neighborhood Hits	71	Shared Neighborhood Hits	18
SwissProt Accessions	P20592	Gene names	MX2
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx2 (Interferon-regulated resistance GTP-binding protein MxB) (p78-related protein).

OPA1_MOUSE
NC score	0.688954 (rank : 12)	θ value	2.59989e-23 (rank : 13)
Query Neighborhood Hits	168	Target Neighborhood Hits	79	Shared Neighborhood Hits	19
SwissProt Accessions	P58281, Q3ULA5, Q8BKU7, Q8BLL3, Q8BM08, Q8R3J7	Gene names	Opa1
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1 homolog) (Large GTP-binding protein) (LargeG) [Contains: Dynamin-like 120 kDa protein, form S1].

OPA1_HUMAN
NC score	0.686077 (rank : 13)	θ value	2.59989e-23 (rank : 12)
Query Neighborhood Hits	168	Target Neighborhood Hits	85	Shared Neighborhood Hits	19
SwissProt Accessions	O60313	Gene names	OPA1, KIAA0567
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1) [Contains: Dynamin-like 120 kDa protein, form S1].

CNKR1_HUMAN
NC score	0.152735 (rank : 14)	θ value	0.0330416 (rank : 21)
Query Neighborhood Hits	168	Target Neighborhood Hits	154	Shared Neighborhood Hits	39
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CNKR2_HUMAN
NC score	0.133502 (rank : 15)	θ value	0.0736092 (rank : 24)
Query Neighborhood Hits	168	Target Neighborhood Hits	197	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
NC score	0.133383 (rank : 16)	θ value	0.0736092 (rank : 25)
Query Neighborhood Hits	168	Target Neighborhood Hits	197	Shared Neighborhood Hits	30
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CYH1_HUMAN
NC score	0.132221 (rank : 17)	θ value	0.00134147 (rank : 15)
Query Neighborhood Hits	168	Target Neighborhood Hits	184	Shared Neighborhood Hits	32
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH1_MOUSE
NC score	0.131527 (rank : 18)	θ value	0.00134147 (rank : 16)
Query Neighborhood Hits	168	Target Neighborhood Hits	176	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH3_HUMAN
NC score	0.129425 (rank : 19)	θ value	0.0148317 (rank : 17)
Query Neighborhood Hits	168	Target Neighborhood Hits	137	Shared Neighborhood Hits	29
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH3_MOUSE
NC score	0.126472 (rank : 20)	θ value	0.0252991 (rank : 20)
Query Neighborhood Hits	168	Target Neighborhood Hits	148	Shared Neighborhood Hits	30
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

CYH2_HUMAN
NC score	0.123307 (rank : 21)	θ value	0.0252991 (rank : 18)
Query Neighborhood Hits	168	Target Neighborhood Hits	175	Shared Neighborhood Hits	29
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
NC score	0.123177 (rank : 22)	θ value	0.0252991 (rank : 19)
Query Neighborhood Hits	168	Target Neighborhood Hits	171	Shared Neighborhood Hits	28
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH4_MOUSE
NC score	0.105342 (rank : 23)	θ value	1.38821 (rank : 83)
Query Neighborhood Hits	168	Target Neighborhood Hits	134	Shared Neighborhood Hits	28
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

CYH4_HUMAN
NC score	0.100229 (rank : 24)	θ value	3.0926 (rank : 108)
Query Neighborhood Hits	168	Target Neighborhood Hits	135	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

PKHA6_HUMAN
NC score	0.098819 (rank : 25)	θ value	1.81305 (rank : 97)
Query Neighborhood Hits	168	Target Neighborhood Hits	556	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA5_HUMAN
NC score	0.093828 (rank : 26)	θ value	0.365318 (rank : 53)
Query Neighborhood Hits	168	Target Neighborhood Hits	455	Shared Neighborhood Hits	40
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PKHA6_MOUSE
NC score	0.092861 (rank : 27)	θ value	4.03905 (rank : 125)
Query Neighborhood Hits	168	Target Neighborhood Hits	591	Shared Neighborhood Hits	63
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

OGFR_HUMAN
NC score	0.082812 (rank : 28)	θ value	0.0736092 (rank : 26)
Query Neighborhood Hits	168	Target Neighborhood Hits	1582	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PKHB1_HUMAN
NC score	0.078157 (rank : 29)	θ value	1.06291 (rank : 73)
Query Neighborhood Hits	168	Target Neighborhood Hits	46	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UF11, Q9UBF5, Q9UI37, Q9UI44	Gene names	PLEKHB1, KPL1, PHR1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

MRIP_HUMAN
NC score	0.077885 (rank : 30)	θ value	0.21417 (rank : 43)
Query Neighborhood Hits	168	Target Neighborhood Hits	578	Shared Neighborhood Hits	51
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

MRIP_MOUSE
NC score	0.077285 (rank : 31)	θ value	0.0961366 (rank : 32)
Query Neighborhood Hits	168	Target Neighborhood Hits	569	Shared Neighborhood Hits	52
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

PRRT3_HUMAN
NC score	0.076696 (rank : 32)	θ value	0.21417 (rank : 44)
Query Neighborhood Hits	168	Target Neighborhood Hits	998	Shared Neighborhood Hits	62
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

CEL_HUMAN
NC score	0.075218 (rank : 33)	θ value	4.92598e-06 (rank : 14)
Query Neighborhood Hits	168	Target Neighborhood Hits	896	Shared Neighborhood Hits	61
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

BCL9_HUMAN
NC score	0.074916 (rank : 34)	θ value	0.0431538 (rank : 22)
Query Neighborhood Hits	168	Target Neighborhood Hits	1008	Shared Neighborhood Hits	69
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

TARA_MOUSE
NC score	0.074331 (rank : 35)	θ value	0.163984 (rank : 41)
Query Neighborhood Hits	168	Target Neighborhood Hits	1133	Shared Neighborhood Hits	78
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

RHG25_MOUSE
NC score	0.073912 (rank : 36)	θ value	0.47712 (rank : 61)
Query Neighborhood Hits	168	Target Neighborhood Hits	492	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

PKHA4_HUMAN
NC score	0.072674 (rank : 37)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	168	Target Neighborhood Hits	283	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHB1_MOUSE
NC score	0.072251 (rank : 38)	θ value	1.06291 (rank : 74)
Query Neighborhood Hits	168	Target Neighborhood Hits	47	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QYE9, Q9QYB3, Q9QYB4, Q9QYD2, Q9QYD3	Gene names	Plekhb1, Phr1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

RHG25_HUMAN
NC score	0.072024 (rank : 39)	θ value	0.279714 (rank : 49)
Query Neighborhood Hits	168	Target Neighborhood Hits	550	Shared Neighborhood Hits	40
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

PRP2_MOUSE
NC score	0.069109 (rank : 40)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	168	Target Neighborhood Hits	347	Shared Neighborhood Hits	76
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PKHA4_MOUSE
NC score	0.064017 (rank : 41)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	168	Target Neighborhood Hits	202	Shared Neighborhood Hits	39
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

BCL9_MOUSE
NC score	0.062335 (rank : 42)	θ value	0.47712 (rank : 56)
Query Neighborhood Hits	168	Target Neighborhood Hits	770	Shared Neighborhood Hits	63
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

IF4B_HUMAN
NC score	0.062236 (rank : 43)	θ value	0.163984 (rank : 38)
Query Neighborhood Hits	168	Target Neighborhood Hits	417	Shared Neighborhood Hits	22
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

PRP1_HUMAN
NC score	0.061765 (rank : 44)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	168	Target Neighborhood Hits	385	Shared Neighborhood Hits	69
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

SC24A_MOUSE
NC score	0.060355 (rank : 45)	θ value	0.163984 (rank : 40)
Query Neighborhood Hits	168	Target Neighborhood Hits	394	Shared Neighborhood Hits	49
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

NCOA6_HUMAN
NC score	0.059518 (rank : 46)	θ value	0.279714 (rank : 48)
Query Neighborhood Hits	168	Target Neighborhood Hits	1202	Shared Neighborhood Hits	69
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PLEK_HUMAN
NC score	0.058147 (rank : 47)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	168	Target Neighborhood Hits	110	Shared Neighborhood Hits	23
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

IF4B_MOUSE
NC score	0.057664 (rank : 48)	θ value	0.62314 (rank : 63)
Query Neighborhood Hits	168	Target Neighborhood Hits	368	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

PRB3_HUMAN
NC score	0.057400 (rank : 49)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	168	Target Neighborhood Hits	318	Shared Neighborhood Hits	60
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
NC score	0.056809 (rank : 50)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	168	Target Neighborhood Hits	330	Shared Neighborhood Hits	61
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

SC24C_HUMAN
NC score	0.056768 (rank : 51)	θ value	0.365318 (rank : 54)
Query Neighborhood Hits	168	Target Neighborhood Hits	662	Shared Neighborhood Hits	55
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

CN032_HUMAN
NC score	0.055152 (rank : 52)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	168	Target Neighborhood Hits	267	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CE016_HUMAN
NC score	0.054477 (rank : 53)	θ value	0.0961366 (rank : 30)
Query Neighborhood Hits	168	Target Neighborhood Hits	80	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NC24, Q6P4E7, Q6UXY2	Gene names	C5orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf16.

NCOA6_MOUSE
NC score	0.053657 (rank : 54)	θ value	0.47712 (rank : 60)
Query Neighborhood Hits	168	Target Neighborhood Hits	1076	Shared Neighborhood Hits	66
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

MFN1_HUMAN
NC score	0.052020 (rank : 55)	θ value	5.27518 (rank : 137)
Query Neighborhood Hits	168	Target Neighborhood Hits	71	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IWA4, O15323, O60639, Q9BZB5, Q9NWQ2	Gene names	MFN1
Domain Architecture
Description	Transmembrane GTPase MFN1 (EC 3.6.5.-) (Mitofusin-1) (Fzo homolog).

EPN3_MOUSE
NC score	0.051942 (rank : 56)	θ value	0.47712 (rank : 59)
Query Neighborhood Hits	168	Target Neighborhood Hits	312	Shared Neighborhood Hits	31
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

CN032_MOUSE
NC score	0.051813 (rank : 57)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	168	Target Neighborhood Hits	233	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CK024_HUMAN
NC score	0.051447 (rank : 58)	θ value	0.279714 (rank : 46)
Query Neighborhood Hits	168	Target Neighborhood Hits	408	Shared Neighborhood Hits	33
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

PKHA1_HUMAN
NC score	0.050779 (rank : 59)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	168	Target Neighborhood Hits	127	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PELP1_MOUSE
NC score	0.049155 (rank : 60)	θ value	0.813845 (rank : 68)
Query Neighborhood Hits	168	Target Neighborhood Hits	709	Shared Neighborhood Hits	58
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

EPN2_HUMAN
NC score	0.049006 (rank : 61)	θ value	0.0961366 (rank : 31)
Query Neighborhood Hits	168	Target Neighborhood Hits	156	Shared Neighborhood Hits	21
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

SON_HUMAN
NC score	0.047245 (rank : 62)	θ value	5.27518 (rank : 141)
Query Neighborhood Hits	168	Target Neighborhood Hits	1568	Shared Neighborhood Hits	73
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

ZIMP7_HUMAN
NC score	0.047128 (rank : 63)	θ value	0.62314 (rank : 65)
Query Neighborhood Hits	168	Target Neighborhood Hits	290	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

S23IP_MOUSE
NC score	0.045274 (rank : 64)	θ value	0.279714 (rank : 50)
Query Neighborhood Hits	168	Target Neighborhood Hits	363	Shared Neighborhood Hits	40
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

ZIM10_HUMAN
NC score	0.043707 (rank : 65)	θ value	1.06291 (rank : 77)
Query Neighborhood Hits	168	Target Neighborhood Hits	577	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

DIDO1_HUMAN
NC score	0.043014 (rank : 66)	θ value	0.21417 (rank : 42)
Query Neighborhood Hits	168	Target Neighborhood Hits	960	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

BSN_MOUSE
NC score	0.041033 (rank : 67)	θ value	2.36792 (rank : 101)
Query Neighborhood Hits	168	Target Neighborhood Hits	2057	Shared Neighborhood Hits	98
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CU086_HUMAN
NC score	0.040874 (rank : 68)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	168	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	P59089	Gene names	C21orf86
Domain Architecture	No domain graphic available
Description	Protein C21orf86.

AKAP2_HUMAN
NC score	0.040829 (rank : 69)	θ value	0.163984 (rank : 37)
Query Neighborhood Hits	168	Target Neighborhood Hits	507	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

MUC1_HUMAN
NC score	0.040516 (rank : 70)	θ value	0.813845 (rank : 67)
Query Neighborhood Hits	168	Target Neighborhood Hits	975	Shared Neighborhood Hits	63
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

ZIMP7_MOUSE
NC score	0.040209 (rank : 71)	θ value	4.03905 (rank : 127)
Query Neighborhood Hits	168	Target Neighborhood Hits	566	Shared Neighborhood Hits	48
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

JPH2_HUMAN
NC score	0.038501 (rank : 72)	θ value	0.163984 (rank : 39)
Query Neighborhood Hits	168	Target Neighborhood Hits	639	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

NRX2B_HUMAN
NC score	0.037884 (rank : 73)	θ value	1.81305 (rank : 96)
Query Neighborhood Hits	168	Target Neighborhood Hits	481	Shared Neighborhood Hits	40
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

SRRM1_MOUSE
NC score	0.037878 (rank : 74)	θ value	5.27518 (rank : 142)
Query Neighborhood Hits	168	Target Neighborhood Hits	966	Shared Neighborhood Hits	59
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

EPN3_HUMAN
NC score	0.037429 (rank : 75)	θ value	1.81305 (rank : 91)
Query Neighborhood Hits	168	Target Neighborhood Hits	197	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

RGS3_MOUSE
NC score	0.037275 (rank : 76)	θ value	6.88961 (rank : 152)
Query Neighborhood Hits	168	Target Neighborhood Hits	1621	Shared Neighborhood Hits	75
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CRTC1_HUMAN
NC score	0.037099 (rank : 77)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	168	Target Neighborhood Hits	319	Shared Neighborhood Hits	48
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

MLL2_HUMAN
NC score	0.036578 (rank : 78)	θ value	3.0926 (rank : 110)
Query Neighborhood Hits	168	Target Neighborhood Hits	1788	Shared Neighborhood Hits	101
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PSMF1_MOUSE
NC score	0.036521 (rank : 79)	θ value	1.06291 (rank : 75)
Query Neighborhood Hits	168	Target Neighborhood Hits	85	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BHL8, Q8C0G9	Gene names	Psmf1
Domain Architecture	No domain graphic available
Description	Proteasome inhibitor PI31 subunit.

TLE1_MOUSE
NC score	0.036008 (rank : 80)	θ value	0.0961366 (rank : 34)
Query Neighborhood Hits	168	Target Neighborhood Hits	491	Shared Neighborhood Hits	25
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

ZIM10_MOUSE
NC score	0.035593 (rank : 81)	θ value	5.27518 (rank : 143)
Query Neighborhood Hits	168	Target Neighborhood Hits	430	Shared Neighborhood Hits	41
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

CECR2_HUMAN
NC score	0.035393 (rank : 82)	θ value	0.47712 (rank : 58)
Query Neighborhood Hits	168	Target Neighborhood Hits	543	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

NACAM_MOUSE
NC score	0.035298 (rank : 83)	θ value	5.27518 (rank : 138)
Query Neighborhood Hits	168	Target Neighborhood Hits	1866	Shared Neighborhood Hits	79
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

K1802_MOUSE
NC score	0.034629 (rank : 84)	θ value	0.279714 (rank : 47)
Query Neighborhood Hits	168	Target Neighborhood Hits	1596	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

TLE1_HUMAN
NC score	0.034562 (rank : 85)	θ value	0.365318 (rank : 55)
Query Neighborhood Hits	168	Target Neighborhood Hits	485	Shared Neighborhood Hits	26
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

K1802_HUMAN
NC score	0.034374 (rank : 86)	θ value	0.62314 (rank : 64)
Query Neighborhood Hits	168	Target Neighborhood Hits	1378	Shared Neighborhood Hits	68
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

TLE4_HUMAN
NC score	0.034229 (rank : 87)	θ value	0.125558 (rank : 35)
Query Neighborhood Hits	168	Target Neighborhood Hits	477	Shared Neighborhood Hits	19
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

TLE4_MOUSE
NC score	0.034216 (rank : 88)	θ value	0.125558 (rank : 36)
Query Neighborhood Hits	168	Target Neighborhood Hits	482	Shared Neighborhood Hits	19
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

CIC_HUMAN
NC score	0.033868 (rank : 89)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	168	Target Neighborhood Hits	992	Shared Neighborhood Hits	74
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

C2TA_HUMAN
NC score	0.033282 (rank : 90)	θ value	0.47712 (rank : 57)
Query Neighborhood Hits	168	Target Neighborhood Hits	190	Shared Neighborhood Hits	17
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

BAG4_HUMAN
NC score	0.032841 (rank : 91)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	168	Target Neighborhood Hits	96	Shared Neighborhood Hits	12
SwissProt Accessions	O95429, O95818	Gene names	BAG4, SODD
Domain Architecture
Description	BAG family molecular chaperone regulator 4 (BCL2-associated athanogene 4) (BAG-4) (Silencer of death domains).

MLL3_HUMAN
NC score	0.032127 (rank : 92)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	168	Target Neighborhood Hits	1644	Shared Neighborhood Hits	70
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MUCDL_HUMAN
NC score	0.032083 (rank : 93)	θ value	1.38821 (rank : 86)
Query Neighborhood Hits	168	Target Neighborhood Hits	777	Shared Neighborhood Hits	59
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

HPS4_HUMAN
NC score	0.031274 (rank : 94)	θ value	1.38821 (rank : 85)
Query Neighborhood Hits	168	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NQG7, Q5H8V6, Q96LX6, Q9BY93, Q9UH37, Q9UH38	Gene names	HPS4, KIAA1667
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 4 protein (Light-ear protein homolog).

TROAP_HUMAN
NC score	0.030767 (rank : 95)	θ value	4.03905 (rank : 126)
Query Neighborhood Hits	168	Target Neighborhood Hits	258	Shared Neighborhood Hits	25
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

PCLO_HUMAN
NC score	0.030423 (rank : 96)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	168	Target Neighborhood Hits	2046	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

MTSS1_MOUSE
NC score	0.029065 (rank : 97)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	168	Target Neighborhood Hits	592	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

MAML2_HUMAN
NC score	0.028200 (rank : 98)	θ value	4.03905 (rank : 122)
Query Neighborhood Hits	168	Target Neighborhood Hits	360	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

PCLO_MOUSE
NC score	0.028061 (rank : 99)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	168	Target Neighborhood Hits	2275	Shared Neighborhood Hits	92
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

ZN598_HUMAN
NC score	0.027817 (rank : 100)	θ value	6.88961 (rank : 155)
Query Neighborhood Hits	168	Target Neighborhood Hits	339	Shared Neighborhood Hits	43
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

CRSP2_HUMAN
NC score	0.027672 (rank : 101)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	168	Target Neighborhood Hits	380	Shared Neighborhood Hits	43
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

NFAC1_HUMAN
NC score	0.027449 (rank : 102)	θ value	1.38821 (rank : 88)
Query Neighborhood Hits	168	Target Neighborhood Hits	312	Shared Neighborhood Hits	36
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

MAP1A_HUMAN
NC score	0.026247 (rank : 103)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	168	Target Neighborhood Hits	1626	Shared Neighborhood Hits	73
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

SCEL_HUMAN
NC score	0.026183 (rank : 104)	θ value	1.81305 (rank : 98)
Query Neighborhood Hits	168	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	O95171	Gene names	SCEL
Domain Architecture
Description	Sciellin.

RIF1_MOUSE
NC score	0.025411 (rank : 105)	θ value	1.06291 (rank : 76)
Query Neighborhood Hits	168	Target Neighborhood Hits	315	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

SAPS1_HUMAN
NC score	0.025394 (rank : 106)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	168	Target Neighborhood Hits	704	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

COG8_MOUSE
NC score	0.025358 (rank : 107)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	168	Target Neighborhood Hits	147	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JJA2	Gene names	Cog8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

ZN385_HUMAN
NC score	0.025201 (rank : 108)	θ value	1.38821 (rank : 89)
Query Neighborhood Hits	168	Target Neighborhood Hits	614	Shared Neighborhood Hits	36
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

NRX2A_HUMAN
NC score	0.025088 (rank : 109)	θ value	1.81305 (rank : 95)
Query Neighborhood Hits	168	Target Neighborhood Hits	614	Shared Neighborhood Hits	41
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

ASTL_HUMAN
NC score	0.024444 (rank : 110)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	168	Target Neighborhood Hits	252	Shared Neighborhood Hits	31
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

BCAR1_MOUSE
NC score	0.024241 (rank : 111)	θ value	0.813845 (rank : 66)
Query Neighborhood Hits	168	Target Neighborhood Hits	438	Shared Neighborhood Hits	31
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

GLYG2_HUMAN
NC score	0.024127 (rank : 112)	θ value	2.36792 (rank : 104)
Query Neighborhood Hits	168	Target Neighborhood Hits	65	Shared Neighborhood Hits	8
SwissProt Accessions	O15488, O15485, O15486, O15487, O15489, O15490	Gene names	GYG2
Domain Architecture
Description	Glycogenin-2 (EC 2.4.1.186) (GN-2) (GN2).

FYCO1_HUMAN
NC score	0.023404 (rank : 113)	θ value	1.81305 (rank : 92)
Query Neighborhood Hits	168	Target Neighborhood Hits	1149	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

CSKI1_HUMAN
NC score	0.023067 (rank : 114)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	168	Target Neighborhood Hits	997	Shared Neighborhood Hits	73
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

MYO15_HUMAN
NC score	0.022452 (rank : 115)	θ value	0.365318 (rank : 52)
Query Neighborhood Hits	168	Target Neighborhood Hits	671	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

SYNP2_HUMAN
NC score	0.022271 (rank : 116)	θ value	3.0926 (rank : 113)
Query Neighborhood Hits	168	Target Neighborhood Hits	323	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

MILK1_MOUSE
NC score	0.022188 (rank : 117)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	168	Target Neighborhood Hits	788	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

CCD37_MOUSE
NC score	0.021416 (rank : 118)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	168	Target Neighborhood Hits	199	Shared Neighborhood Hits	13
SwissProt Accessions	Q80VN0, Q6AXD6	Gene names	Ccdc37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

SYNE2_HUMAN
NC score	0.021272 (rank : 119)	θ value	0.21417 (rank : 45)
Query Neighborhood Hits	168	Target Neighborhood Hits	1323	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

KI67_HUMAN
NC score	0.021193 (rank : 120)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	168	Target Neighborhood Hits	581	Shared Neighborhood Hits	27
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

CSTF2_HUMAN
NC score	0.019109 (rank : 121)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	168	Target Neighborhood Hits	296	Shared Neighborhood Hits	14
SwissProt Accessions	P33240, Q5H951, Q6LA74, Q8N502	Gene names	CSTF2
Domain Architecture
Description	Cleavage stimulation factor 64 kDa subunit (CSTF 64 kDa subunit) (CF-1 64 kDa subunit) (CstF-64).

RBCC1_MOUSE
NC score	0.018953 (rank : 122)	θ value	3.0926 (rank : 111)
Query Neighborhood Hits	168	Target Neighborhood Hits	1048	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

RP3A_MOUSE
NC score	0.018716 (rank : 123)	θ value	0.813845 (rank : 69)
Query Neighborhood Hits	168	Target Neighborhood Hits	510	Shared Neighborhood Hits	41
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

MEGF9_MOUSE
NC score	0.018651 (rank : 124)	θ value	1.81305 (rank : 94)
Query Neighborhood Hits	168	Target Neighborhood Hits	896	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

RUNX1_MOUSE
NC score	0.018117 (rank : 125)	θ value	0.47712 (rank : 62)
Query Neighborhood Hits	168	Target Neighborhood Hits	93	Shared Neighborhood Hits	7
SwissProt Accessions	Q03347, O08598, Q62049, Q9ESB9, Q9ET65	Gene names	Runx1, Aml1, Cbfa2, Pebp2ab
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

RBCC1_HUMAN
NC score	0.017797 (rank : 126)	θ value	6.88961 (rank : 151)
Query Neighborhood Hits	168	Target Neighborhood Hits	1023	Shared Neighborhood Hits	29
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

ROCK1_HUMAN
NC score	0.017691 (rank : 127)	θ value	0.0961366 (rank : 33)
Query Neighborhood Hits	168	Target Neighborhood Hits	2000	Shared Neighborhood Hits	50
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

BIM_HUMAN
NC score	0.017524 (rank : 128)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	168	Target Neighborhood Hits	134	Shared Neighborhood Hits	8
SwissProt Accessions	O43521, O43522	Gene names	BCL2L11, BIM
Domain Architecture
Description	Bcl-2-like protein 11 (Bcl2-interacting mediator of cell death).

ROCK1_MOUSE
NC score	0.017397 (rank : 129)	θ value	0.0736092 (rank : 27)
Query Neighborhood Hits	168	Target Neighborhood Hits	2126	Shared Neighborhood Hits	53
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

SMRD2_MOUSE
NC score	0.017354 (rank : 130)	θ value	1.81305 (rank : 99)
Query Neighborhood Hits	168	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q99JR8	Gene names	Smarcd2, Baf60b
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 (60 kDa BRG-1/Brm-associated factor subunit B) (BRG1-associated factor 60B).

NCOA3_MOUSE
NC score	0.017082 (rank : 131)	θ value	1.38821 (rank : 87)
Query Neighborhood Hits	168	Target Neighborhood Hits	203	Shared Neighborhood Hits	17
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

ELOA2_HUMAN
NC score	0.017056 (rank : 132)	θ value	2.36792 (rank : 103)
Query Neighborhood Hits	168	Target Neighborhood Hits	165	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IYF1, Q9P2V9	Gene names	TCEB3B, TCEB3L
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A2 (Elongin-A2) (EloA2) (Transcription elongation factor B polypeptide 3B).

AATK_HUMAN
NC score	0.016852 (rank : 133)	θ value	0.0961366 (rank : 29)
Query Neighborhood Hits	168	Target Neighborhood Hits	1243	Shared Neighborhood Hits	52
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

JIP3_HUMAN
NC score	0.016810 (rank : 134)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	168	Target Neighborhood Hits	1039	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

HXB3_HUMAN
NC score	0.016735 (rank : 135)	θ value	0.0431538 (rank : 23)
Query Neighborhood Hits	168	Target Neighborhood Hits	559	Shared Neighborhood Hits	25
SwissProt Accessions	P14651, O95615, P17484	Gene names	HOXB3, HOX2G
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7).

IL9R_HUMAN
NC score	0.015943 (rank : 136)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	168	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q01113, Q14634, Q8WWU1, Q96TF0	Gene names	IL9R
Domain Architecture	No domain graphic available
Description	Interleukin-9 receptor precursor (IL-9R) (CD129 antigen).

GRAP1_MOUSE
NC score	0.015913 (rank : 137)	θ value	3.0926 (rank : 109)
Query Neighborhood Hits	168	Target Neighborhood Hits	1234	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

SYNG_MOUSE
NC score	0.015540 (rank : 138)	θ value	6.88961 (rank : 153)
Query Neighborhood Hits	168	Target Neighborhood Hits	206	Shared Neighborhood Hits	17
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

PHC2_HUMAN
NC score	0.015086 (rank : 139)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	168	Target Neighborhood Hits	388	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

AMOL1_MOUSE
NC score	0.014719 (rank : 140)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	168	Target Neighborhood Hits	445	Shared Neighborhood Hits	22
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

K2C6B_MOUSE
NC score	0.014654 (rank : 141)	θ value	1.81305 (rank : 93)
Query Neighborhood Hits	168	Target Neighborhood Hits	506	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z331	Gene names	Krt6b, K6-beta, Krt2-6b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin) (Keratin-6 beta) (mK6-beta).

EGR4_HUMAN
NC score	0.014178 (rank : 142)	θ value	1.38821 (rank : 84)
Query Neighborhood Hits	168	Target Neighborhood Hits	939	Shared Neighborhood Hits	22
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

UGGG2_HUMAN
NC score	0.013973 (rank : 143)	θ value	3.0926 (rank : 115)
Query Neighborhood Hits	168	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYU1, Q9UFC4	Gene names	UGCGL2, UGT2
Domain Architecture
Description	UDP-glucose:glycoprotein glucosyltransferase 2 precursor (EC 2.4.1.-) (UDP-glucose ceramide glucosyltransferase-like 1) (UDP-- Glc:glycoprotein glucosyltransferase 2) (HUGT2).

CO9A1_MOUSE
NC score	0.013934 (rank : 144)	θ value	2.36792 (rank : 102)
Query Neighborhood Hits	168	Target Neighborhood Hits	477	Shared Neighborhood Hits	44
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

GOGA4_HUMAN
NC score	0.013644 (rank : 145)	θ value	4.03905 (rank : 121)
Query Neighborhood Hits	168	Target Neighborhood Hits	2034	Shared Neighborhood Hits	44
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

CP250_MOUSE
NC score	0.013102 (rank : 146)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	168	Target Neighborhood Hits	1583	Shared Neighborhood Hits	39
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

POMT2_MOUSE
NC score	0.012972 (rank : 147)	θ value	5.27518 (rank : 140)
Query Neighborhood Hits	168	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGQ4, Q8R4Z0	Gene names	Pomt2
Domain Architecture
Description	Protein O-mannosyl-transferase 2 (EC 2.4.1.109) (Dolichyl-phosphate- mannose--protein mannosyltransferase 2).

LSD1_HUMAN
NC score	0.012950 (rank : 148)	θ value	5.27518 (rank : 136)
Query Neighborhood Hits	168	Target Neighborhood Hits	455	Shared Neighborhood Hits	29
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

CENPE_HUMAN
NC score	0.012731 (rank : 149)	θ value	1.81305 (rank : 90)
Query Neighborhood Hits	168	Target Neighborhood Hits	2060	Shared Neighborhood Hits	51
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

SPEG_HUMAN
NC score	0.012587 (rank : 150)	θ value	0.813845 (rank : 70)
Query Neighborhood Hits	168	Target Neighborhood Hits	1762	Shared Neighborhood Hits	72
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPEG_MOUSE
NC score	0.012343 (rank : 151)	θ value	3.0926 (rank : 112)
Query Neighborhood Hits	168	Target Neighborhood Hits	1959	Shared Neighborhood Hits	73
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

CING_MOUSE
NC score	0.012184 (rank : 152)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	168	Target Neighborhood Hits	1432	Shared Neighborhood Hits	39
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

SLK_MOUSE
NC score	0.011522 (rank : 153)	θ value	0.0736092 (rank : 28)
Query Neighborhood Hits	168	Target Neighborhood Hits	1798	Shared Neighborhood Hits	44
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

CAC1B_HUMAN
NC score	0.010895 (rank : 154)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	168	Target Neighborhood Hits	257	Shared Neighborhood Hits	19
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

DESM_MOUSE
NC score	0.010738 (rank : 155)	θ value	1.06291 (rank : 72)
Query Neighborhood Hits	168	Target Neighborhood Hits	498	Shared Neighborhood Hits	21
SwissProt Accessions	P31001	Gene names	Des
Domain Architecture
Description	Desmin.

ALDR_HUMAN
NC score	0.010599 (rank : 156)	θ value	2.36792 (rank : 100)
Query Neighborhood Hits	168	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P15121, Q9BS21, Q9UCI9	Gene names	AKR1B1, ALDR1
Domain Architecture
Description	Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase).

SLK_HUMAN
NC score	0.010566 (rank : 157)	θ value	0.279714 (rank : 51)
Query Neighborhood Hits	168	Target Neighborhood Hits	1775	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

AP3D1_MOUSE
NC score	0.009937 (rank : 158)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	168	Target Neighborhood Hits	144	Shared Neighborhood Hits	10
SwissProt Accessions	O54774	Gene names	Ap3d1, Ap3d
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin) (mBLVR1).

TBCD1_HUMAN
NC score	0.009890 (rank : 159)	θ value	6.88961 (rank : 154)
Query Neighborhood Hits	168	Target Neighborhood Hits	276	Shared Neighborhood Hits	14
SwissProt Accessions	Q86TI0, Q96K82, Q9UPP4	Gene names	TBC1D1, KIAA1108
Domain Architecture
Description	TBC1 domain family member 1.

ANGL1_MOUSE
NC score	0.009642 (rank : 160)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	168	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	Q640P2, Q3UQL1, Q9CZ81	Gene names	Angptl1
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 1 precursor (Angiopoietin-like 1).

AP3D1_HUMAN
NC score	0.008830 (rank : 161)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	168	Target Neighborhood Hits	254	Shared Neighborhood Hits	11
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

DESM_HUMAN
NC score	0.008718 (rank : 162)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	168	Target Neighborhood Hits	495	Shared Neighborhood Hits	22
SwissProt Accessions	P17661, Q15787, Q8IZR1, Q8IZR6, Q8NES2, Q8NEU6, Q8TAC4, Q8TCX2, Q8TD99, Q9UHN5, Q9UJ80	Gene names	DES
Domain Architecture
Description	Desmin.

TITIN_HUMAN
NC score	0.008651 (rank : 163)	θ value	3.0926 (rank : 114)
Query Neighborhood Hits	168	Target Neighborhood Hits	2923	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

SIM2_HUMAN
NC score	0.008335 (rank : 164)	θ value	2.36792 (rank : 105)
Query Neighborhood Hits	168	Target Neighborhood Hits	76	Shared Neighborhood Hits	7
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

SOX17_MOUSE
NC score	0.007537 (rank : 165)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	168	Target Neighborhood Hits	223	Shared Neighborhood Hits	25
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

FOG1_MOUSE
NC score	0.007317 (rank : 166)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	168	Target Neighborhood Hits	1237	Shared Neighborhood Hits	55
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

HXD3_HUMAN
NC score	0.007280 (rank : 167)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	168	Target Neighborhood Hits	433	Shared Neighborhood Hits	26
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

KCNQ4_HUMAN
NC score	0.007154 (rank : 168)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	168	Target Neighborhood Hits	136	Shared Neighborhood Hits	6
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

PAK4_MOUSE
NC score	0.006770 (rank : 169)	θ value	5.27518 (rank : 139)
Query Neighborhood Hits	168	Target Neighborhood Hits	1098	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

BMX_HUMAN
NC score	0.006526 (rank : 170)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	168	Target Neighborhood Hits	942	Shared Neighborhood Hits	26
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

ZN516_MOUSE
NC score	0.006257 (rank : 171)	θ value	5.27518 (rank : 144)
Query Neighborhood Hits	168	Target Neighborhood Hits	1197	Shared Neighborhood Hits	40
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

COKA1_HUMAN
NC score	0.006201 (rank : 172)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	168	Target Neighborhood Hits	403	Shared Neighborhood Hits	24
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

MAST1_HUMAN
NC score	0.005917 (rank : 173)	θ value	4.03905 (rank : 123)
Query Neighborhood Hits	168	Target Neighborhood Hits	1146	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

BMX_MOUSE
NC score	0.005124 (rank : 174)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	168	Target Neighborhood Hits	912	Shared Neighborhood Hits	25
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

ICK_MOUSE
NC score	0.003429 (rank : 175)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	168	Target Neighborhood Hits	860	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JKV2, Q8K138	Gene names	Ick
Domain Architecture
Description	Serine/threonine-protein kinase ICK (EC 2.7.11.22) (Intestinal cell kinase) (mICK) (MAK-related kinase) (MRK).

ICK_HUMAN
NC score	0.002943 (rank : 176)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	168	Target Neighborhood Hits	867	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UPZ9, O75985, Q5THL2, Q8IYH8, Q9BX17, Q9NYX3	Gene names	ICK, KIAA0936
Domain Architecture
Description	Serine/threonine-protein kinase ICK (EC 2.7.11.22) (Intestinal cell kinase) (hICK) (MAK-related kinase) (MRK) (Laryngeal cancer kinase 2) (LCK2).

AT2A3_MOUSE
NC score	0.002821 (rank : 177)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	168	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	Q64518, O70625, Q64517	Gene names	Atp2a3
Domain Architecture
Description	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (EC 3.6.3.8) (Calcium pump 3) (SERCA3) (SR Ca(2+)-ATPase 3).

GLI2_HUMAN
NC score	0.000277 (rank : 178)	θ value	4.03905 (rank : 120)
Query Neighborhood Hits	168	Target Neighborhood Hits	971	Shared Neighborhood Hits	27
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).