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Network neighborhood for query Sequence : DOCK9_MOUSE

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DOCK9_MOUSE
SwissProt Accessions	Q8BIK4, Q921Y6	Gene names	Dock9, D14Wsu89e, Kiaa1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DOC10_HUMAN
θ value	0 (rank : 1)	NC score	0.978787 (rank : 3)
Query Neighborhood Hits	79	Target Neighborhood Hits	88	Shared Neighborhood Hits	35
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).

DOCK6_HUMAN
θ value	0 (rank : 2)	NC score	0.923869 (rank : 4)
Query Neighborhood Hits	79	Target Neighborhood Hits	71	Shared Neighborhood Hits	15
SwissProt Accessions	Q96HP0, Q9P2F2	Gene names	DOCK6, KIAA1395
Domain Architecture
Description	Dedicator of cytokinesis protein 6.

DOCK9_HUMAN
θ value	0 (rank : 3)	NC score	0.996438 (rank : 2)
Query Neighborhood Hits	79	Target Neighborhood Hits	82	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BZ29, Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26, Q9BZ27, Q9BZ28, Q9UPU4	Gene names	DOCK9, KIAA1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

DOCK9_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	79	Target Neighborhood Hits	79	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BIK4, Q921Y6	Gene names	Dock9, D14Wsu89e, Kiaa1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

DOCK7_HUMAN
θ value	1.41594e-162 (rank : 5)	NC score	0.917749 (rank : 5)
Query Neighborhood Hits	79	Target Neighborhood Hits	29	Shared Neighborhood Hits	15
SwissProt Accessions	Q96N67, Q6ZV32, Q8TB82, Q96NG6, Q9C092	Gene names	DOCK7, KIAA1771
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 7.

DOCK8_HUMAN
θ value	1.12453e-151 (rank : 6)	NC score	0.905137 (rank : 7)
Query Neighborhood Hits	79	Target Neighborhood Hits	42	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NF50, Q3MV16, Q5JPJ1, Q8TEP1, Q8WUY2, Q9BYJ5, Q9H1Q2, Q9H1Q3, Q9H308, Q9H7P2	Gene names	DOCK8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

DOCK8_MOUSE
θ value	1.4755e-135 (rank : 7)	NC score	0.915002 (rank : 6)
Query Neighborhood Hits	79	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C147, Q6PIS0, Q7TMQ5, Q8K105, Q9DBQ2	Gene names	Dock8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

DOCK3_HUMAN
θ value	3.63628e-17 (rank : 8)	NC score	0.455938 (rank : 8)
Query Neighborhood Hits	79	Target Neighborhood Hits	87	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IZD9, O15017	Gene names	DOCK3, KIAA0299, MOCA
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

DOCK3_MOUSE
θ value	8.10077e-17 (rank : 9)	NC score	0.455303 (rank : 9)
Query Neighborhood Hits	79	Target Neighborhood Hits	93	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CIQ7	Gene names	Dock3, Moca
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

DOCK4_HUMAN
θ value	3.52202e-12 (rank : 10)	NC score	0.418971 (rank : 10)
Query Neighborhood Hits	79	Target Neighborhood Hits	237	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOCK4_MOUSE
θ value	4.59992e-12 (rank : 11)	NC score	0.417854 (rank : 11)
Query Neighborhood Hits	79	Target Neighborhood Hits	210	Shared Neighborhood Hits	14
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOCK2_MOUSE
θ value	6.64225e-11 (rank : 12)	NC score	0.406678 (rank : 13)
Query Neighborhood Hits	79	Target Neighborhood Hits	104	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C3J5, Q99M79	Gene names	Dock2
Domain Architecture
Description	Dedicator of cytokinesis protein 2 (Hch protein).

DOCK1_HUMAN
θ value	1.133e-10 (rank : 13)	NC score	0.394920 (rank : 14)
Query Neighborhood Hits	79	Target Neighborhood Hits	191	Shared Neighborhood Hits	14
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

DOCK2_HUMAN
θ value	2.52405e-10 (rank : 14)	NC score	0.407731 (rank : 12)
Query Neighborhood Hits	79	Target Neighborhood Hits	90	Shared Neighborhood Hits	16
SwissProt Accessions	Q92608, Q96AK7	Gene names	DOCK2, KIAA0209
Domain Architecture
Description	Dedicator of cytokinesis protein 2.

DP13B_HUMAN
θ value	4.1701e-05 (rank : 15)	NC score	0.064964 (rank : 34)
Query Neighborhood Hits	79	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEU8, Q8N4R7, Q9NVL2	Gene names	DIP13B, APPL2
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

RHG25_HUMAN
θ value	4.1701e-05 (rank : 16)	NC score	0.115192 (rank : 18)
Query Neighborhood Hits	79	Target Neighborhood Hits	550	Shared Neighborhood Hits	34
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

PKHA6_MOUSE
θ value	0.000786445 (rank : 17)	NC score	0.116296 (rank : 16)
Query Neighborhood Hits	79	Target Neighborhood Hits	591	Shared Neighborhood Hits	38
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

SPTN2_HUMAN
θ value	0.000786445 (rank : 18)	NC score	0.045905 (rank : 39)
Query Neighborhood Hits	79	Target Neighborhood Hits	535	Shared Neighborhood Hits	22
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

RHG25_MOUSE
θ value	0.00102713 (rank : 19)	NC score	0.104855 (rank : 22)
Query Neighborhood Hits	79	Target Neighborhood Hits	492	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

IRS1_HUMAN
θ value	0.00298849 (rank : 20)	NC score	0.095109 (rank : 24)
Query Neighborhood Hits	79	Target Neighborhood Hits	109	Shared Neighborhood Hits	12
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

IRS1_MOUSE
θ value	0.00298849 (rank : 21)	NC score	0.093657 (rank : 25)
Query Neighborhood Hits	79	Target Neighborhood Hits	112	Shared Neighborhood Hits	11
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

PKHA5_HUMAN
θ value	0.00298849 (rank : 22)	NC score	0.108455 (rank : 21)
Query Neighborhood Hits	79	Target Neighborhood Hits	455	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

CENB1_HUMAN
θ value	0.00665767 (rank : 23)	NC score	0.056388 (rank : 37)
Query Neighborhood Hits	79	Target Neighborhood Hits	383	Shared Neighborhood Hits	21
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB2_HUMAN
θ value	0.0193708 (rank : 24)	NC score	0.058771 (rank : 36)
Query Neighborhood Hits	79	Target Neighborhood Hits	425	Shared Neighborhood Hits	26
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

GAB2_MOUSE
θ value	0.0330416 (rank : 25)	NC score	0.115411 (rank : 17)
Query Neighborhood Hits	79	Target Neighborhood Hits	220	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

PKHA4_MOUSE
θ value	0.0431538 (rank : 26)	NC score	0.108952 (rank : 20)
Query Neighborhood Hits	79	Target Neighborhood Hits	202	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

GAB1_MOUSE
θ value	0.0563607 (rank : 27)	NC score	0.109079 (rank : 19)
Query Neighborhood Hits	79	Target Neighborhood Hits	233	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAB2_HUMAN
θ value	0.0563607 (rank : 28)	NC score	0.128184 (rank : 15)
Query Neighborhood Hits	79	Target Neighborhood Hits	188	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

PKHA4_HUMAN
θ value	0.0563607 (rank : 29)	NC score	0.104065 (rank : 23)
Query Neighborhood Hits	79	Target Neighborhood Hits	283	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

DAPP1_HUMAN
θ value	0.125558 (rank : 30)	NC score	0.071159 (rank : 30)
Query Neighborhood Hits	79	Target Neighborhood Hits	227	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	0.125558 (rank : 31)	NC score	0.071369 (rank : 29)
Query Neighborhood Hits	79	Target Neighborhood Hits	225	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

CENPF_HUMAN
θ value	0.163984 (rank : 32)	NC score	0.018950 (rank : 53)
Query Neighborhood Hits	79	Target Neighborhood Hits	1932	Shared Neighborhood Hits	25
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

GAB1_HUMAN
θ value	0.163984 (rank : 33)	NC score	0.091566 (rank : 26)
Query Neighborhood Hits	79	Target Neighborhood Hits	279	Shared Neighborhood Hits	21
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

UACA_HUMAN
θ value	0.163984 (rank : 34)	NC score	0.016246 (rank : 59)
Query Neighborhood Hits	79	Target Neighborhood Hits	1622	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

OSBP1_HUMAN
θ value	0.365318 (rank : 35)	NC score	0.037739 (rank : 40)
Query Neighborhood Hits	79	Target Neighborhood Hits	180	Shared Neighborhood Hits	20
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

PLEK_HUMAN
θ value	0.365318 (rank : 36)	NC score	0.087485 (rank : 27)
Query Neighborhood Hits	79	Target Neighborhood Hits	110	Shared Neighborhood Hits	27
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

HD_HUMAN
θ value	0.62314 (rank : 37)	NC score	0.028630 (rank : 45)
Query Neighborhood Hits	79	Target Neighborhood Hits	165	Shared Neighborhood Hits	5
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

SPTB2_HUMAN
θ value	0.813845 (rank : 38)	NC score	0.033902 (rank : 41)
Query Neighborhood Hits	79	Target Neighborhood Hits	748	Shared Neighborhood Hits	21
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTB2_MOUSE
θ value	0.813845 (rank : 39)	NC score	0.032915 (rank : 43)
Query Neighborhood Hits	79	Target Neighborhood Hits	770	Shared Neighborhood Hits	21
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

RDH12_MOUSE
θ value	1.06291 (rank : 40)	NC score	0.011707 (rank : 67)
Query Neighborhood Hits	79	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BYK4, Q91WA5, Q9D1Y4	Gene names	Rdh12
Domain Architecture
Description	Retinol dehydrogenase 12 (EC 1.1.1.-).

PLEK_MOUSE
θ value	1.38821 (rank : 41)	NC score	0.073690 (rank : 28)
Query Neighborhood Hits	79	Target Neighborhood Hits	109	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

CHSTB_MOUSE
θ value	1.81305 (rank : 42)	NC score	0.015922 (rank : 60)
Query Neighborhood Hits	79	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JME2, Q9JJS2	Gene names	Chst11
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O- sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4ST) (C4ST-1) (C4S-1).

K0226_HUMAN
θ value	1.81305 (rank : 43)	NC score	0.025178 (rank : 47)
Query Neighborhood Hits	79	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q92622	Gene names	KIAA0226
Domain Architecture	No domain graphic available
Description	Protein KIAA0226.

SPTN4_HUMAN
θ value	1.81305 (rank : 44)	NC score	0.033078 (rank : 42)
Query Neighborhood Hits	79	Target Neighborhood Hits	570	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

XPO4_MOUSE
θ value	1.81305 (rank : 45)	NC score	0.017025 (rank : 55)
Query Neighborhood Hits	79	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ESJ0, Q6ZPJ4	Gene names	Xpo4, Kiaa1721
Domain Architecture	No domain graphic available
Description	Exportin-4 (Exp4).

NOC3L_HUMAN
θ value	2.36792 (rank : 46)	NC score	0.026869 (rank : 46)
Query Neighborhood Hits	79	Target Neighborhood Hits	135	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WTT2, Q9H5M6, Q9H9D8	Gene names	NOC3L, AD24, C10orf117, FAD24
Domain Architecture	No domain graphic available
Description	Nucleolar complex protein 3 homolog (NOC3 protein homolog) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein) (Factor for adipocyte differentiation 24).

PKHA1_HUMAN
θ value	2.36792 (rank : 47)	NC score	0.066350 (rank : 33)
Query Neighborhood Hits	79	Target Neighborhood Hits	127	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PLCG1_MOUSE
θ value	2.36792 (rank : 48)	NC score	0.020845 (rank : 48)
Query Neighborhood Hits	79	Target Neighborhood Hits	314	Shared Neighborhood Hits	9
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLEK2_HUMAN
θ value	2.36792 (rank : 49)	NC score	0.070202 (rank : 31)
Query Neighborhood Hits	79	Target Neighborhood Hits	101	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

DYR1A_HUMAN
θ value	3.0926 (rank : 50)	NC score	0.003432 (rank : 77)
Query Neighborhood Hits	79	Target Neighborhood Hits	764	Shared Neighborhood Hits	6
SwissProt Accessions	Q13627, O60769, Q92582, Q92810, Q9UNM5	Gene names	DYRK1A, DYRK, MNB, MNBH
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Protein kinase minibrain homolog) (MNBH) (HP86) (Dual specificity YAK1-related kinase).

UBN1_HUMAN
θ value	3.0926 (rank : 51)	NC score	0.029103 (rank : 44)
Query Neighborhood Hits	79	Target Neighborhood Hits	170	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NPG3, Q13079, Q9P1P7	Gene names	UBN1
Domain Architecture	No domain graphic available
Description	Ubinuclein (Ubiquitously expressed nuclear protein) (VT4).

DMD_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.019402 (rank : 52)
Query Neighborhood Hits	79	Target Neighborhood Hits	1135	Shared Neighborhood Hits	19
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

DSPP_HUMAN
θ value	4.03905 (rank : 53)	NC score	0.017320 (rank : 54)
Query Neighborhood Hits	79	Target Neighborhood Hits	645	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

GOGB1_HUMAN
θ value	4.03905 (rank : 54)	NC score	0.016707 (rank : 58)
Query Neighborhood Hits	79	Target Neighborhood Hits	2297	Shared Neighborhood Hits	28
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

MASTL_MOUSE
θ value	4.03905 (rank : 55)	NC score	0.000751 (rank : 79)
Query Neighborhood Hits	79	Target Neighborhood Hits	862	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C0P0, Q5RJW0, Q6NXX9, Q8BVF3, Q9CZH9, Q9D9V0	Gene names	Mastl
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

TRIPB_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.012035 (rank : 66)
Query Neighborhood Hits	79	Target Neighborhood Hits	1587	Shared Neighborhood Hits	25
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CT112_MOUSE
θ value	5.27518 (rank : 57)	NC score	0.019721 (rank : 51)
Query Neighborhood Hits	79	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	Q6DIB4	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf112 homolog.

K0319_HUMAN
θ value	5.27518 (rank : 58)	NC score	0.019903 (rank : 50)
Query Neighborhood Hits	79	Target Neighborhood Hits	154	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VV43, Q9UJC8, Q9Y4G7	Gene names	KIAA0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

MASTL_HUMAN
θ value	5.27518 (rank : 59)	NC score	0.000434 (rank : 81)
Query Neighborhood Hits	79	Target Neighborhood Hits	894	Shared Neighborhood Hits	5
SwissProt Accessions	Q96GX5, Q5T8D5, Q5T8D7, Q8NCD6, Q96SJ5	Gene names	MASTL, THC2
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

MYH14_MOUSE
θ value	5.27518 (rank : 60)	NC score	0.008930 (rank : 69)
Query Neighborhood Hits	79	Target Neighborhood Hits	1225	Shared Neighborhood Hits	19
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

ANK2_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.006428 (rank : 75)
Query Neighborhood Hits	79	Target Neighborhood Hits	1615	Shared Neighborhood Hits	19
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CP250_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.008079 (rank : 72)
Query Neighborhood Hits	79	Target Neighborhood Hits	1805	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CT011_HUMAN
θ value	6.88961 (rank : 63)	NC score	0.016860 (rank : 56)
Query Neighborhood Hits	79	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NWU2, Q8N5M5	Gene names	C20orf11
Domain Architecture
Description	Protein C20orf11 (Two-hybrid associated protein 1 with RanBPM) (Twa1).

CT011_MOUSE
θ value	6.88961 (rank : 64)	NC score	0.016776 (rank : 57)
Query Neighborhood Hits	79	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D7M1	Gene names
Domain Architecture
Description	Protein C20orf11 homolog (Two-hybrid associated protein 1 with RanBPM) (Twa1).

CTRO_MOUSE
θ value	6.88961 (rank : 65)	NC score	0.003269 (rank : 78)
Query Neighborhood Hits	79	Target Neighborhood Hits	2344	Shared Neighborhood Hits	25
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CUL1_HUMAN
θ value	6.88961 (rank : 66)	NC score	0.008203 (rank : 70)
Query Neighborhood Hits	79	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q13616, O60719, Q8IYW1	Gene names	CUL1
Domain Architecture
Description	Cullin-1 (CUL-1).

CUL1_MOUSE
θ value	6.88961 (rank : 67)	NC score	0.008203 (rank : 71)
Query Neighborhood Hits	79	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WTX6, Q9WUI7	Gene names	Cul1
Domain Architecture
Description	Cullin-1 (CUL-1).

DMD_MOUSE
θ value	6.88961 (rank : 68)	NC score	0.020147 (rank : 49)
Query Neighborhood Hits	79	Target Neighborhood Hits	1111	Shared Neighborhood Hits	24
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

HXA3_HUMAN
θ value	6.88961 (rank : 69)	NC score	0.000510 (rank : 80)
Query Neighborhood Hits	79	Target Neighborhood Hits	535	Shared Neighborhood Hits	2
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

PLEK2_MOUSE
θ value	6.88961 (rank : 70)	NC score	0.061553 (rank : 35)
Query Neighborhood Hits	79	Target Neighborhood Hits	96	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

RFC1_MOUSE
θ value	6.88961 (rank : 71)	NC score	0.008005 (rank : 73)
Query Neighborhood Hits	79	Target Neighborhood Hits	290	Shared Neighborhood Hits	5
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

SDC2_MOUSE
θ value	6.88961 (rank : 72)	NC score	0.012388 (rank : 65)
Query Neighborhood Hits	79	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	P43407	Gene names	Sdc2, Hspg1, Synd2
Domain Architecture
Description	Syndecan-2 precursor (SYND2) (Fibroglycan) (Heparan sulfate proteoglycan core protein) (HSPG).

TTC3_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.014287 (rank : 62)
Query Neighborhood Hits	79	Target Neighborhood Hits	664	Shared Neighborhood Hits	14
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

ATM_HUMAN
θ value	8.99809 (rank : 74)	NC score	0.005612 (rank : 76)
Query Neighborhood Hits	79	Target Neighborhood Hits	78	Shared Neighborhood Hits	5
SwissProt Accessions	Q13315, O15429, Q12758, Q16551, Q93007, Q9NP02, Q9UCX7	Gene names	ATM
Domain Architecture
Description	Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T, mutated).

BACH_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.013260 (rank : 64)
Query Neighborhood Hits	79	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	O00154, O43703, Q5JYL4, Q9UJM9, Q9Y539, Q9Y540	Gene names	ACOT7, BACH
Domain Architecture
Description	Cytosolic acyl coenzyme A thioester hydrolase (EC 3.1.2.2) (Long chain acyl-CoA thioester hydrolase) (CTE-II) (CTE-IIa) (Brain acyl-CoA hydrolase) (Acyl-CoA thioesterase 7).

FETUA_MOUSE
θ value	8.99809 (rank : 76)	NC score	0.009212 (rank : 68)
Query Neighborhood Hits	79	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	P29699, O35634	Gene names	Ahsg, Fetua
Domain Architecture
Description	Alpha-2-HS-glycoprotein precursor (Fetuin-A) (Countertrypin).

FGD5_HUMAN
θ value	8.99809 (rank : 77)	NC score	0.013329 (rank : 63)
Query Neighborhood Hits	79	Target Neighborhood Hits	235	Shared Neighborhood Hits	13
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

LGP2_HUMAN
θ value	8.99809 (rank : 78)	NC score	0.007994 (rank : 74)
Query Neighborhood Hits	79	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

PLCG1_HUMAN
θ value	8.99809 (rank : 79)	NC score	0.015250 (rank : 61)
Query Neighborhood Hits	79	Target Neighborhood Hits	293	Shared Neighborhood Hits	8
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PKHA1_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.055316 (rank : 38)
Query Neighborhood Hits	79	Target Neighborhood Hits	120	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA6_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.069024 (rank : 32)
Query Neighborhood Hits	79	Target Neighborhood Hits	556	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

Hits sorted by NC score

DOCK9_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	79	Target Neighborhood Hits	79	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BIK4, Q921Y6	Gene names	Dock9, D14Wsu89e, Kiaa1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

DOCK9_HUMAN
NC score	0.996438 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	79	Target Neighborhood Hits	82	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BZ29, Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26, Q9BZ27, Q9BZ28, Q9UPU4	Gene names	DOCK9, KIAA1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

DOC10_HUMAN
NC score	0.978787 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	79	Target Neighborhood Hits	88	Shared Neighborhood Hits	35
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).

DOCK6_HUMAN
NC score	0.923869 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	79	Target Neighborhood Hits	71	Shared Neighborhood Hits	15
SwissProt Accessions	Q96HP0, Q9P2F2	Gene names	DOCK6, KIAA1395
Domain Architecture
Description	Dedicator of cytokinesis protein 6.

DOCK7_HUMAN
NC score	0.917749 (rank : 5)	θ value	1.41594e-162 (rank : 5)
Query Neighborhood Hits	79	Target Neighborhood Hits	29	Shared Neighborhood Hits	15
SwissProt Accessions	Q96N67, Q6ZV32, Q8TB82, Q96NG6, Q9C092	Gene names	DOCK7, KIAA1771
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 7.

DOCK8_MOUSE
NC score	0.915002 (rank : 6)	θ value	1.4755e-135 (rank : 7)
Query Neighborhood Hits	79	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C147, Q6PIS0, Q7TMQ5, Q8K105, Q9DBQ2	Gene names	Dock8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

DOCK8_HUMAN
NC score	0.905137 (rank : 7)	θ value	1.12453e-151 (rank : 6)
Query Neighborhood Hits	79	Target Neighborhood Hits	42	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NF50, Q3MV16, Q5JPJ1, Q8TEP1, Q8WUY2, Q9BYJ5, Q9H1Q2, Q9H1Q3, Q9H308, Q9H7P2	Gene names	DOCK8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

DOCK3_HUMAN
NC score	0.455938 (rank : 8)	θ value	3.63628e-17 (rank : 8)
Query Neighborhood Hits	79	Target Neighborhood Hits	87	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IZD9, O15017	Gene names	DOCK3, KIAA0299, MOCA
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

DOCK3_MOUSE
NC score	0.455303 (rank : 9)	θ value	8.10077e-17 (rank : 9)
Query Neighborhood Hits	79	Target Neighborhood Hits	93	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CIQ7	Gene names	Dock3, Moca
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

DOCK4_HUMAN
NC score	0.418971 (rank : 10)	θ value	3.52202e-12 (rank : 10)
Query Neighborhood Hits	79	Target Neighborhood Hits	237	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOCK4_MOUSE
NC score	0.417854 (rank : 11)	θ value	4.59992e-12 (rank : 11)
Query Neighborhood Hits	79	Target Neighborhood Hits	210	Shared Neighborhood Hits	14
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOCK2_HUMAN
NC score	0.407731 (rank : 12)	θ value	2.52405e-10 (rank : 14)
Query Neighborhood Hits	79	Target Neighborhood Hits	90	Shared Neighborhood Hits	16
SwissProt Accessions	Q92608, Q96AK7	Gene names	DOCK2, KIAA0209
Domain Architecture
Description	Dedicator of cytokinesis protein 2.

DOCK2_MOUSE
NC score	0.406678 (rank : 13)	θ value	6.64225e-11 (rank : 12)
Query Neighborhood Hits	79	Target Neighborhood Hits	104	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C3J5, Q99M79	Gene names	Dock2
Domain Architecture
Description	Dedicator of cytokinesis protein 2 (Hch protein).

DOCK1_HUMAN
NC score	0.394920 (rank : 14)	θ value	1.133e-10 (rank : 13)
Query Neighborhood Hits	79	Target Neighborhood Hits	191	Shared Neighborhood Hits	14
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

GAB2_HUMAN
NC score	0.128184 (rank : 15)	θ value	0.0563607 (rank : 28)
Query Neighborhood Hits	79	Target Neighborhood Hits	188	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

PKHA6_MOUSE
NC score	0.116296 (rank : 16)	θ value	0.000786445 (rank : 17)
Query Neighborhood Hits	79	Target Neighborhood Hits	591	Shared Neighborhood Hits	38
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

GAB2_MOUSE
NC score	0.115411 (rank : 17)	θ value	0.0330416 (rank : 25)
Query Neighborhood Hits	79	Target Neighborhood Hits	220	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

RHG25_HUMAN
NC score	0.115192 (rank : 18)	θ value	4.1701e-05 (rank : 16)
Query Neighborhood Hits	79	Target Neighborhood Hits	550	Shared Neighborhood Hits	34
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

GAB1_MOUSE
NC score	0.109079 (rank : 19)	θ value	0.0563607 (rank : 27)
Query Neighborhood Hits	79	Target Neighborhood Hits	233	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

PKHA4_MOUSE
NC score	0.108952 (rank : 20)	θ value	0.0431538 (rank : 26)
Query Neighborhood Hits	79	Target Neighborhood Hits	202	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA5_HUMAN
NC score	0.108455 (rank : 21)	θ value	0.00298849 (rank : 22)
Query Neighborhood Hits	79	Target Neighborhood Hits	455	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

RHG25_MOUSE
NC score	0.104855 (rank : 22)	θ value	0.00102713 (rank : 19)
Query Neighborhood Hits	79	Target Neighborhood Hits	492	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

PKHA4_HUMAN
NC score	0.104065 (rank : 23)	θ value	0.0563607 (rank : 29)
Query Neighborhood Hits	79	Target Neighborhood Hits	283	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

IRS1_HUMAN
NC score	0.095109 (rank : 24)	θ value	0.00298849 (rank : 20)
Query Neighborhood Hits	79	Target Neighborhood Hits	109	Shared Neighborhood Hits	12
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

IRS1_MOUSE
NC score	0.093657 (rank : 25)	θ value	0.00298849 (rank : 21)
Query Neighborhood Hits	79	Target Neighborhood Hits	112	Shared Neighborhood Hits	11
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

GAB1_HUMAN
NC score	0.091566 (rank : 26)	θ value	0.163984 (rank : 33)
Query Neighborhood Hits	79	Target Neighborhood Hits	279	Shared Neighborhood Hits	21
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

PLEK_HUMAN
NC score	0.087485 (rank : 27)	θ value	0.365318 (rank : 36)
Query Neighborhood Hits	79	Target Neighborhood Hits	110	Shared Neighborhood Hits	27
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PLEK_MOUSE
NC score	0.073690 (rank : 28)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	79	Target Neighborhood Hits	109	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

DAPP1_MOUSE
NC score	0.071369 (rank : 29)	θ value	0.125558 (rank : 31)
Query Neighborhood Hits	79	Target Neighborhood Hits	225	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_HUMAN
NC score	0.071159 (rank : 30)	θ value	0.125558 (rank : 30)
Query Neighborhood Hits	79	Target Neighborhood Hits	227	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

PLEK2_HUMAN
NC score	0.070202 (rank : 31)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	79	Target Neighborhood Hits	101	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PKHA6_HUMAN
NC score	0.069024 (rank : 32)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	79	Target Neighborhood Hits	556	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA1_HUMAN
NC score	0.066350 (rank : 33)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	79	Target Neighborhood Hits	127	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

DP13B_HUMAN
NC score	0.064964 (rank : 34)	θ value	4.1701e-05 (rank : 15)
Query Neighborhood Hits	79	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEU8, Q8N4R7, Q9NVL2	Gene names	DIP13B, APPL2
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

PLEK2_MOUSE
NC score	0.061553 (rank : 35)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	79	Target Neighborhood Hits	96	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

CENB2_HUMAN
NC score	0.058771 (rank : 36)	θ value	0.0193708 (rank : 24)
Query Neighborhood Hits	79	Target Neighborhood Hits	425	Shared Neighborhood Hits	26
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB1_HUMAN
NC score	0.056388 (rank : 37)	θ value	0.00665767 (rank : 23)
Query Neighborhood Hits	79	Target Neighborhood Hits	383	Shared Neighborhood Hits	21
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

PKHA1_MOUSE
NC score	0.055316 (rank : 38)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	79	Target Neighborhood Hits	120	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

SPTN2_HUMAN
NC score	0.045905 (rank : 39)	θ value	0.000786445 (rank : 18)
Query Neighborhood Hits	79	Target Neighborhood Hits	535	Shared Neighborhood Hits	22
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

OSBP1_HUMAN
NC score	0.037739 (rank : 40)	θ value	0.365318 (rank : 35)
Query Neighborhood Hits	79	Target Neighborhood Hits	180	Shared Neighborhood Hits	20
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

SPTB2_HUMAN
NC score	0.033902 (rank : 41)	θ value	0.813845 (rank : 38)
Query Neighborhood Hits	79	Target Neighborhood Hits	748	Shared Neighborhood Hits	21
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTN4_HUMAN
NC score	0.033078 (rank : 42)	θ value	1.81305 (rank : 44)
Query Neighborhood Hits	79	Target Neighborhood Hits	570	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

SPTB2_MOUSE
NC score	0.032915 (rank : 43)	θ value	0.813845 (rank : 39)
Query Neighborhood Hits	79	Target Neighborhood Hits	770	Shared Neighborhood Hits	21
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

UBN1_HUMAN
NC score	0.029103 (rank : 44)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	79	Target Neighborhood Hits	170	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NPG3, Q13079, Q9P1P7	Gene names	UBN1
Domain Architecture	No domain graphic available
Description	Ubinuclein (Ubiquitously expressed nuclear protein) (VT4).

HD_HUMAN
NC score	0.028630 (rank : 45)	θ value	0.62314 (rank : 37)
Query Neighborhood Hits	79	Target Neighborhood Hits	165	Shared Neighborhood Hits	5
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

NOC3L_HUMAN
NC score	0.026869 (rank : 46)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	79	Target Neighborhood Hits	135	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WTT2, Q9H5M6, Q9H9D8	Gene names	NOC3L, AD24, C10orf117, FAD24
Domain Architecture	No domain graphic available
Description	Nucleolar complex protein 3 homolog (NOC3 protein homolog) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein) (Factor for adipocyte differentiation 24).

K0226_HUMAN
NC score	0.025178 (rank : 47)	θ value	1.81305 (rank : 43)
Query Neighborhood Hits	79	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q92622	Gene names	KIAA0226
Domain Architecture	No domain graphic available
Description	Protein KIAA0226.

PLCG1_MOUSE
NC score	0.020845 (rank : 48)	θ value	2.36792 (rank : 48)
Query Neighborhood Hits	79	Target Neighborhood Hits	314	Shared Neighborhood Hits	9
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

DMD_MOUSE
NC score	0.020147 (rank : 49)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	79	Target Neighborhood Hits	1111	Shared Neighborhood Hits	24
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

K0319_HUMAN
NC score	0.019903 (rank : 50)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	79	Target Neighborhood Hits	154	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VV43, Q9UJC8, Q9Y4G7	Gene names	KIAA0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

CT112_MOUSE
NC score	0.019721 (rank : 51)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	79	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	Q6DIB4	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf112 homolog.

DMD_HUMAN
NC score	0.019402 (rank : 52)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	79	Target Neighborhood Hits	1135	Shared Neighborhood Hits	19
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

CENPF_HUMAN
NC score	0.018950 (rank : 53)	θ value	0.163984 (rank : 32)
Query Neighborhood Hits	79	Target Neighborhood Hits	1932	Shared Neighborhood Hits	25
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

DSPP_HUMAN
NC score	0.017320 (rank : 54)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	79	Target Neighborhood Hits	645	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

XPO4_MOUSE
NC score	0.017025 (rank : 55)	θ value	1.81305 (rank : 45)
Query Neighborhood Hits	79	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ESJ0, Q6ZPJ4	Gene names	Xpo4, Kiaa1721
Domain Architecture	No domain graphic available
Description	Exportin-4 (Exp4).

CT011_HUMAN
NC score	0.016860 (rank : 56)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	79	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NWU2, Q8N5M5	Gene names	C20orf11
Domain Architecture
Description	Protein C20orf11 (Two-hybrid associated protein 1 with RanBPM) (Twa1).

CT011_MOUSE
NC score	0.016776 (rank : 57)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	79	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D7M1	Gene names
Domain Architecture
Description	Protein C20orf11 homolog (Two-hybrid associated protein 1 with RanBPM) (Twa1).

GOGB1_HUMAN
NC score	0.016707 (rank : 58)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	79	Target Neighborhood Hits	2297	Shared Neighborhood Hits	28
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

UACA_HUMAN
NC score	0.016246 (rank : 59)	θ value	0.163984 (rank : 34)
Query Neighborhood Hits	79	Target Neighborhood Hits	1622	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

CHSTB_MOUSE
NC score	0.015922 (rank : 60)	θ value	1.81305 (rank : 42)
Query Neighborhood Hits	79	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JME2, Q9JJS2	Gene names	Chst11
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O- sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4ST) (C4ST-1) (C4S-1).

PLCG1_HUMAN
NC score	0.015250 (rank : 61)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	79	Target Neighborhood Hits	293	Shared Neighborhood Hits	8
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

TTC3_HUMAN
NC score	0.014287 (rank : 62)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	79	Target Neighborhood Hits	664	Shared Neighborhood Hits	14
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

FGD5_HUMAN
NC score	0.013329 (rank : 63)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	79	Target Neighborhood Hits	235	Shared Neighborhood Hits	13
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

BACH_HUMAN
NC score	0.013260 (rank : 64)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	79	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	O00154, O43703, Q5JYL4, Q9UJM9, Q9Y539, Q9Y540	Gene names	ACOT7, BACH
Domain Architecture
Description	Cytosolic acyl coenzyme A thioester hydrolase (EC 3.1.2.2) (Long chain acyl-CoA thioester hydrolase) (CTE-II) (CTE-IIa) (Brain acyl-CoA hydrolase) (Acyl-CoA thioesterase 7).

SDC2_MOUSE
NC score	0.012388 (rank : 65)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	79	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	P43407	Gene names	Sdc2, Hspg1, Synd2
Domain Architecture
Description	Syndecan-2 precursor (SYND2) (Fibroglycan) (Heparan sulfate proteoglycan core protein) (HSPG).

TRIPB_HUMAN
NC score	0.012035 (rank : 66)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	79	Target Neighborhood Hits	1587	Shared Neighborhood Hits	25
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

RDH12_MOUSE
NC score	0.011707 (rank : 67)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	79	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BYK4, Q91WA5, Q9D1Y4	Gene names	Rdh12
Domain Architecture
Description	Retinol dehydrogenase 12 (EC 1.1.1.-).

FETUA_MOUSE
NC score	0.009212 (rank : 68)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	79	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	P29699, O35634	Gene names	Ahsg, Fetua
Domain Architecture
Description	Alpha-2-HS-glycoprotein precursor (Fetuin-A) (Countertrypin).

MYH14_MOUSE
NC score	0.008930 (rank : 69)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	79	Target Neighborhood Hits	1225	Shared Neighborhood Hits	19
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

CUL1_HUMAN
NC score	0.008203 (rank : 70)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	79	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q13616, O60719, Q8IYW1	Gene names	CUL1
Domain Architecture
Description	Cullin-1 (CUL-1).

CUL1_MOUSE
NC score	0.008203 (rank : 71)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	79	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WTX6, Q9WUI7	Gene names	Cul1
Domain Architecture
Description	Cullin-1 (CUL-1).

CP250_HUMAN
NC score	0.008079 (rank : 72)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	79	Target Neighborhood Hits	1805	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

RFC1_MOUSE
NC score	0.008005 (rank : 73)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	79	Target Neighborhood Hits	290	Shared Neighborhood Hits	5
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

LGP2_HUMAN
NC score	0.007994 (rank : 74)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	79	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

ANK2_HUMAN
NC score	0.006428 (rank : 75)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	79	Target Neighborhood Hits	1615	Shared Neighborhood Hits	19
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ATM_HUMAN
NC score	0.005612 (rank : 76)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	79	Target Neighborhood Hits	78	Shared Neighborhood Hits	5
SwissProt Accessions	Q13315, O15429, Q12758, Q16551, Q93007, Q9NP02, Q9UCX7	Gene names	ATM
Domain Architecture
Description	Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T, mutated).

DYR1A_HUMAN
NC score	0.003432 (rank : 77)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	79	Target Neighborhood Hits	764	Shared Neighborhood Hits	6
SwissProt Accessions	Q13627, O60769, Q92582, Q92810, Q9UNM5	Gene names	DYRK1A, DYRK, MNB, MNBH
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Protein kinase minibrain homolog) (MNBH) (HP86) (Dual specificity YAK1-related kinase).

CTRO_MOUSE
NC score	0.003269 (rank : 78)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	79	Target Neighborhood Hits	2344	Shared Neighborhood Hits	25
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

MASTL_MOUSE
NC score	0.000751 (rank : 79)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	79	Target Neighborhood Hits	862	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C0P0, Q5RJW0, Q6NXX9, Q8BVF3, Q9CZH9, Q9D9V0	Gene names	Mastl
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

HXA3_HUMAN
NC score	0.000510 (rank : 80)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	79	Target Neighborhood Hits	535	Shared Neighborhood Hits	2
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

MASTL_HUMAN
NC score	0.000434 (rank : 81)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	79	Target Neighborhood Hits	894	Shared Neighborhood Hits	5
SwissProt Accessions	Q96GX5, Q5T8D5, Q5T8D7, Q8NCD6, Q96SJ5	Gene names	MASTL, THC2
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).