Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : DOC10_HUMAN

For an explanation of this page, click here

DOC10_HUMAN
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DOC10_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	88	Target Neighborhood Hits	88	Shared Neighborhood Hits	88
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).

DOCK9_HUMAN
θ value	0 (rank : 2)	NC score	0.977872 (rank : 3)
Query Neighborhood Hits	88	Target Neighborhood Hits	82	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BZ29, Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26, Q9BZ27, Q9BZ28, Q9UPU4	Gene names	DOCK9, KIAA1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

DOCK9_MOUSE
θ value	0 (rank : 3)	NC score	0.978787 (rank : 2)
Query Neighborhood Hits	88	Target Neighborhood Hits	79	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BIK4, Q921Y6	Gene names	Dock9, D14Wsu89e, Kiaa1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

DOCK7_HUMAN
θ value	4.72459e-150 (rank : 4)	NC score	0.913205 (rank : 4)
Query Neighborhood Hits	88	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q96N67, Q6ZV32, Q8TB82, Q96NG6, Q9C092	Gene names	DOCK7, KIAA1771
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 7.

DOCK6_HUMAN
θ value	1.28961e-139 (rank : 5)	NC score	0.912800 (rank : 5)
Query Neighborhood Hits	88	Target Neighborhood Hits	71	Shared Neighborhood Hits	14
SwissProt Accessions	Q96HP0, Q9P2F2	Gene names	DOCK6, KIAA1395
Domain Architecture
Description	Dedicator of cytokinesis protein 6.

DOCK8_HUMAN
θ value	3.51195e-137 (rank : 6)	NC score	0.901250 (rank : 7)
Query Neighborhood Hits	88	Target Neighborhood Hits	42	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NF50, Q3MV16, Q5JPJ1, Q8TEP1, Q8WUY2, Q9BYJ5, Q9H1Q2, Q9H1Q3, Q9H308, Q9H7P2	Gene names	DOCK8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

DOCK8_MOUSE
θ value	4.58675e-137 (rank : 7)	NC score	0.912780 (rank : 6)
Query Neighborhood Hits	88	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C147, Q6PIS0, Q7TMQ5, Q8K105, Q9DBQ2	Gene names	Dock8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

DOCK3_HUMAN
θ value	1.13037e-18 (rank : 8)	NC score	0.492703 (rank : 8)
Query Neighborhood Hits	88	Target Neighborhood Hits	87	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IZD9, O15017	Gene names	DOCK3, KIAA0299, MOCA
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

DOCK3_MOUSE
θ value	3.28887e-18 (rank : 9)	NC score	0.492096 (rank : 9)
Query Neighborhood Hits	88	Target Neighborhood Hits	93	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CIQ7	Gene names	Dock3, Moca
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

DOCK2_MOUSE
θ value	6.85773e-16 (rank : 10)	NC score	0.448597 (rank : 13)
Query Neighborhood Hits	88	Target Neighborhood Hits	104	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C3J5, Q99M79	Gene names	Dock2
Domain Architecture
Description	Dedicator of cytokinesis protein 2 (Hch protein).

DOCK2_HUMAN
θ value	1.52774e-15 (rank : 11)	NC score	0.449803 (rank : 12)
Query Neighborhood Hits	88	Target Neighborhood Hits	90	Shared Neighborhood Hits	14
SwissProt Accessions	Q92608, Q96AK7	Gene names	DOCK2, KIAA0209
Domain Architecture
Description	Dedicator of cytokinesis protein 2.

DOCK4_HUMAN
θ value	5.8054e-15 (rank : 12)	NC score	0.457602 (rank : 10)
Query Neighborhood Hits	88	Target Neighborhood Hits	237	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOCK4_MOUSE
θ value	9.90251e-15 (rank : 13)	NC score	0.456588 (rank : 11)
Query Neighborhood Hits	88	Target Neighborhood Hits	210	Shared Neighborhood Hits	17
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOCK1_HUMAN
θ value	8.38298e-14 (rank : 14)	NC score	0.435049 (rank : 14)
Query Neighborhood Hits	88	Target Neighborhood Hits	191	Shared Neighborhood Hits	15
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

GAB2_MOUSE
θ value	1.69304e-06 (rank : 15)	NC score	0.141770 (rank : 16)
Query Neighborhood Hits	88	Target Neighborhood Hits	220	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

GAB2_HUMAN
θ value	2.44474e-05 (rank : 16)	NC score	0.153334 (rank : 15)
Query Neighborhood Hits	88	Target Neighborhood Hits	188	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

RHG25_HUMAN
θ value	7.1131e-05 (rank : 17)	NC score	0.115310 (rank : 18)
Query Neighborhood Hits	88	Target Neighborhood Hits	550	Shared Neighborhood Hits	36
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_MOUSE
θ value	0.00035302 (rank : 18)	NC score	0.103007 (rank : 21)
Query Neighborhood Hits	88	Target Neighborhood Hits	492	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

MYO10_HUMAN
θ value	0.00175202 (rank : 19)	NC score	0.031343 (rank : 44)
Query Neighborhood Hits	88	Target Neighborhood Hits	920	Shared Neighborhood Hits	36
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

TARA_HUMAN
θ value	0.00509761 (rank : 20)	NC score	0.050195 (rank : 39)
Query Neighborhood Hits	88	Target Neighborhood Hits	1626	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TARA_MOUSE
θ value	0.00869519 (rank : 21)	NC score	0.063153 (rank : 33)
Query Neighborhood Hits	88	Target Neighborhood Hits	1133	Shared Neighborhood Hits	38
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

GAB1_MOUSE
θ value	0.0148317 (rank : 22)	NC score	0.121136 (rank : 17)
Query Neighborhood Hits	88	Target Neighborhood Hits	233	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

PKHA5_HUMAN
θ value	0.0431538 (rank : 23)	NC score	0.105218 (rank : 20)
Query Neighborhood Hits	88	Target Neighborhood Hits	455	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

GOGB1_HUMAN
θ value	0.0563607 (rank : 24)	NC score	0.025478 (rank : 49)
Query Neighborhood Hits	88	Target Neighborhood Hits	2297	Shared Neighborhood Hits	37
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

PKHA6_MOUSE
θ value	0.0563607 (rank : 25)	NC score	0.111351 (rank : 19)
Query Neighborhood Hits	88	Target Neighborhood Hits	591	Shared Neighborhood Hits	35
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

HMMR_HUMAN
θ value	0.163984 (rank : 26)	NC score	0.022247 (rank : 57)
Query Neighborhood Hits	88	Target Neighborhood Hits	1082	Shared Neighborhood Hits	25
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

PKHA6_HUMAN
θ value	0.163984 (rank : 27)	NC score	0.069328 (rank : 29)
Query Neighborhood Hits	88	Target Neighborhood Hits	556	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

GOGA1_HUMAN
θ value	0.21417 (rank : 28)	NC score	0.021429 (rank : 59)
Query Neighborhood Hits	88	Target Neighborhood Hits	1222	Shared Neighborhood Hits	28
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

IFT81_MOUSE
θ value	0.21417 (rank : 29)	NC score	0.024687 (rank : 50)
Query Neighborhood Hits	88	Target Neighborhood Hits	959	Shared Neighborhood Hits	26
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

NU107_HUMAN
θ value	0.21417 (rank : 30)	NC score	0.044035 (rank : 41)
Query Neighborhood Hits	88	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	P57740	Gene names	NUP107
Domain Architecture
Description	Nuclear pore complex protein Nup107 (Nucleoporin Nup107) (107 kDa nucleoporin).

GOGA4_HUMAN
θ value	0.365318 (rank : 31)	NC score	0.019580 (rank : 60)
Query Neighborhood Hits	88	Target Neighborhood Hits	2034	Shared Neighborhood Hits	35
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

RPC1_HUMAN
θ value	0.47712 (rank : 32)	NC score	0.023881 (rank : 52)
Query Neighborhood Hits	88	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	O14802, Q8TCW5	Gene names	POLR3A
Domain Architecture
Description	DNA-directed RNA polymerase III largest subunit (EC 2.7.7.6) (RPC155) (RPC1).

PKHA1_MOUSE
θ value	0.62314 (rank : 33)	NC score	0.060557 (rank : 34)
Query Neighborhood Hits	88	Target Neighborhood Hits	120	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PLEK2_HUMAN
θ value	0.62314 (rank : 34)	NC score	0.075688 (rank : 27)
Query Neighborhood Hits	88	Target Neighborhood Hits	101	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_MOUSE
θ value	0.62314 (rank : 35)	NC score	0.069338 (rank : 28)
Query Neighborhood Hits	88	Target Neighborhood Hits	96	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

AKAP9_HUMAN
θ value	0.813845 (rank : 36)	NC score	0.019250 (rank : 61)
Query Neighborhood Hits	88	Target Neighborhood Hits	1710	Shared Neighborhood Hits	35
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

LAMB1_MOUSE
θ value	0.813845 (rank : 37)	NC score	0.012900 (rank : 73)
Query Neighborhood Hits	88	Target Neighborhood Hits	919	Shared Neighborhood Hits	21
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

IRS2_MOUSE
θ value	1.06291 (rank : 38)	NC score	0.030170 (rank : 45)
Query Neighborhood Hits	88	Target Neighborhood Hits	248	Shared Neighborhood Hits	10
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

MPP2_MOUSE
θ value	1.06291 (rank : 39)	NC score	0.009698 (rank : 77)
Query Neighborhood Hits	88	Target Neighborhood Hits	189	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

NU107_MOUSE
θ value	1.06291 (rank : 40)	NC score	0.038416 (rank : 42)
Query Neighborhood Hits	88	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BH74, Q99KH5	Gene names	Nup107
Domain Architecture
Description	Nuclear pore complex protein Nup107 (Nucleoporin Nup107) (107 kDa nucleoporin).

PLEK_HUMAN
θ value	1.06291 (rank : 41)	NC score	0.090924 (rank : 24)
Query Neighborhood Hits	88	Target Neighborhood Hits	110	Shared Neighborhood Hits	27
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

SPTB2_HUMAN
θ value	1.06291 (rank : 42)	NC score	0.026853 (rank : 47)
Query Neighborhood Hits	88	Target Neighborhood Hits	748	Shared Neighborhood Hits	32
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

TRI14_HUMAN
θ value	1.06291 (rank : 43)	NC score	0.014299 (rank : 69)
Query Neighborhood Hits	88	Target Neighborhood Hits	143	Shared Neighborhood Hits	3
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

CENPE_HUMAN
θ value	1.38821 (rank : 44)	NC score	0.014002 (rank : 70)
Query Neighborhood Hits	88	Target Neighborhood Hits	2060	Shared Neighborhood Hits	37
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

DP13A_HUMAN
θ value	1.38821 (rank : 45)	NC score	0.023818 (rank : 53)
Query Neighborhood Hits	88	Target Neighborhood Hits	107	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKG1, Q9P2B9	Gene names	APPL1, APPL, DIP13A, KIAA1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

DP13A_MOUSE
θ value	1.38821 (rank : 46)	NC score	0.023577 (rank : 54)
Query Neighborhood Hits	88	Target Neighborhood Hits	96	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K3H0, Q3UJP7, Q69ZJ9, Q8BWZ8, Q8VCJ8, Q9CUW4	Gene names	Appl1, Dip13a, Kiaa1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

IRS2_HUMAN
θ value	1.38821 (rank : 47)	NC score	0.028041 (rank : 46)
Query Neighborhood Hits	88	Target Neighborhood Hits	262	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

LAMB1_HUMAN
θ value	1.38821 (rank : 48)	NC score	0.013276 (rank : 72)
Query Neighborhood Hits	88	Target Neighborhood Hits	1018	Shared Neighborhood Hits	20
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

MRIP_MOUSE
θ value	1.38821 (rank : 49)	NC score	0.056249 (rank : 37)
Query Neighborhood Hits	88	Target Neighborhood Hits	569	Shared Neighborhood Hits	36
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

PLCG1_HUMAN
θ value	1.38821 (rank : 50)	NC score	0.016974 (rank : 64)
Query Neighborhood Hits	88	Target Neighborhood Hits	293	Shared Neighborhood Hits	7
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

FAK2_MOUSE
θ value	1.81305 (rank : 51)	NC score	-0.000228 (rank : 93)
Query Neighborhood Hits	88	Target Neighborhood Hits	851	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

PKHA1_HUMAN
θ value	1.81305 (rank : 52)	NC score	0.068728 (rank : 30)
Query Neighborhood Hits	88	Target Neighborhood Hits	127	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PLCG1_MOUSE
θ value	1.81305 (rank : 53)	NC score	0.021859 (rank : 58)
Query Neighborhood Hits	88	Target Neighborhood Hits	314	Shared Neighborhood Hits	8
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

AKA11_HUMAN
θ value	2.36792 (rank : 54)	NC score	0.022741 (rank : 56)
Query Neighborhood Hits	88	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKA4, O75124, Q9NUK7	Gene names	AKAP11, AKAP220, KIAA0629
Domain Architecture
Description	A-kinase anchor protein 11 (Protein kinase A-anchoring protein 11) (PRKA11) (A kinase anchor protein 220 kDa) (AKAP 220) (hAKAP220).

MRCKA_HUMAN
θ value	2.36792 (rank : 55)	NC score	0.004122 (rank : 90)
Query Neighborhood Hits	88	Target Neighborhood Hits	1999	Shared Neighborhood Hits	30
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

NEB2_MOUSE
θ value	2.36792 (rank : 56)	NC score	0.017333 (rank : 63)
Query Neighborhood Hits	88	Target Neighborhood Hits	889	Shared Neighborhood Hits	24
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

TRI14_MOUSE
θ value	2.36792 (rank : 57)	NC score	0.012558 (rank : 74)
Query Neighborhood Hits	88	Target Neighborhood Hits	137	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

ARK72_HUMAN
θ value	3.0926 (rank : 58)	NC score	0.017446 (rank : 62)
Query Neighborhood Hits	88	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	O43488, O75749, Q5TG63	Gene names	AKR7A2, AFAR, AFAR1, AKR7
Domain Architecture
Description	Aflatoxin B1 aldehyde reductase member 2 (EC 1.-.-.-) (AFB1-AR 1) (Aldoketoreductase 7).

CNKR1_HUMAN
θ value	3.0926 (rank : 59)	NC score	0.047415 (rank : 40)
Query Neighborhood Hits	88	Target Neighborhood Hits	154	Shared Neighborhood Hits	19
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CTNA2_HUMAN
θ value	3.0926 (rank : 60)	NC score	0.014617 (rank : 68)
Query Neighborhood Hits	88	Target Neighborhood Hits	74	Shared Neighborhood Hits	9
SwissProt Accessions	P26232, Q4ZFW1, Q53R26, Q53R33, Q53T67, Q53T71, Q53TM8, Q7Z3Y0	Gene names	CTNNA2, CAPR
Domain Architecture
Description	Catenin alpha-2 (Alpha-catenin-related protein) (Alpha N-catenin).

CTNA2_MOUSE
θ value	3.0926 (rank : 61)	NC score	0.014626 (rank : 67)
Query Neighborhood Hits	88	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	Q61301, Q61300, Q6AXD1	Gene names	Ctnna2, Catna2
Domain Architecture
Description	Catenin alpha-2 (Alpha-catenin-related protein) (Alpha N-catenin).

DMXL1_HUMAN
θ value	3.0926 (rank : 62)	NC score	0.009986 (rank : 76)
Query Neighborhood Hits	88	Target Neighborhood Hits	259	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y485	Gene names	DMXL1, XL1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

PKHA4_MOUSE
θ value	3.0926 (rank : 63)	NC score	0.095333 (rank : 23)
Query Neighborhood Hits	88	Target Neighborhood Hits	202	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

SPTB2_MOUSE
θ value	3.0926 (rank : 64)	NC score	0.025709 (rank : 48)
Query Neighborhood Hits	88	Target Neighborhood Hits	770	Shared Neighborhood Hits	32
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

TTC7A_HUMAN
θ value	3.0926 (rank : 65)	NC score	0.013435 (rank : 71)
Query Neighborhood Hits	88	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULT0, Q6PIX4, Q8ND67, Q9BUS3	Gene names	TTC7A, KIAA1140, TTC7
Domain Architecture
Description	Tetratricopeptide repeat protein 7A (TPR repeat protein 7).

IFT81_HUMAN
θ value	4.03905 (rank : 66)	NC score	0.022814 (rank : 55)
Query Neighborhood Hits	88	Target Neighborhood Hits	893	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

MRIP_HUMAN
θ value	4.03905 (rank : 67)	NC score	0.055975 (rank : 38)
Query Neighborhood Hits	88	Target Neighborhood Hits	578	Shared Neighborhood Hits	34
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

PKHA4_HUMAN
θ value	4.03905 (rank : 68)	NC score	0.088553 (rank : 25)
Query Neighborhood Hits	88	Target Neighborhood Hits	283	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

ACHB2_HUMAN
θ value	5.27518 (rank : 69)	NC score	0.004764 (rank : 87)
Query Neighborhood Hits	88	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	P17787, Q9UEH9	Gene names	CHRNB2
Domain Architecture
Description	Neuronal acetylcholine receptor protein subunit beta-2 precursor.

ACHB2_MOUSE
θ value	5.27518 (rank : 70)	NC score	0.004755 (rank : 88)
Query Neighborhood Hits	88	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ERK7	Gene names	Chrnb2
Domain Architecture	No domain graphic available
Description	Neuronal acetylcholine receptor protein subunit beta-2 precursor.

ACOX3_MOUSE
θ value	5.27518 (rank : 71)	NC score	0.009015 (rank : 81)
Query Neighborhood Hits	88	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EPL9	Gene names	Acox3
Domain Architecture
Description	Acyl-coenzyme A oxidase 3, peroxisomal (EC 1.3.3.6) (Pristanoyl-CoA oxidase) (Branched-chain acyl-CoA oxidase) (BRCACox).

ARK72_MOUSE
θ value	5.27518 (rank : 72)	NC score	0.015388 (rank : 66)
Query Neighborhood Hits	88	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CG76, Q3UPU2, Q8CG77, Q8JZQ8, Q9D157	Gene names	Akr7a2, Afar, Akr7a5
Domain Architecture
Description	Aflatoxin B1 aldehyde reductase member 2 (EC 1.-.-.-).

CALR3_MOUSE
θ value	5.27518 (rank : 73)	NC score	0.009429 (rank : 78)
Query Neighborhood Hits	88	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D9Q6	Gene names	Calr3, Crt2
Domain Architecture
Description	Calreticulin-3 precursor (Calreticulin-2).

K2C6B_HUMAN
θ value	5.27518 (rank : 74)	NC score	0.005661 (rank : 85)
Query Neighborhood Hits	88	Target Neighborhood Hits	526	Shared Neighborhood Hits	18
SwissProt Accessions	P04259, P48669	Gene names	KRT6B, K6B
Domain Architecture
Description	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin).

K2C6E_HUMAN
θ value	5.27518 (rank : 75)	NC score	0.005597 (rank : 86)
Query Neighborhood Hits	88	Target Neighborhood Hits	516	Shared Neighborhood Hits	16
SwissProt Accessions	P48668, Q7RTN9	Gene names	KRT6E
Domain Architecture
Description	Keratin, type II cytoskeletal 6E (Cytokeratin-6E) (CK 6E) (K6e keratin) (Keratin K6h).

NEB2_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.015863 (rank : 65)
Query Neighborhood Hits	88	Target Neighborhood Hits	883	Shared Neighborhood Hits	24
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

PLEK_MOUSE
θ value	5.27518 (rank : 77)	NC score	0.077407 (rank : 26)
Query Neighborhood Hits	88	Target Neighborhood Hits	109	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

RHES_MOUSE
θ value	5.27518 (rank : 78)	NC score	0.003279 (rank : 91)
Query Neighborhood Hits	88	Target Neighborhood Hits	236	Shared Neighborhood Hits	3
SwissProt Accessions	P63032, Q9WVD3	Gene names	Rasd2
Domain Architecture	No domain graphic available
Description	GTP-binding protein Rhes (Ras homolog enriched in striatum).

SIRT1_MOUSE
θ value	5.27518 (rank : 79)	NC score	0.009194 (rank : 80)
Query Neighborhood Hits	88	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q923E4, Q9QXG8	Gene names	Sirt1, Sir2l1
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-1 (EC 3.5.1.-) (SIR2alpha) (mSIR2a) (Sir2) (SIR2-like protein 1).

SPTN2_HUMAN
θ value	5.27518 (rank : 80)	NC score	0.031854 (rank : 43)
Query Neighborhood Hits	88	Target Neighborhood Hits	535	Shared Neighborhood Hits	24
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

SPTN4_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.024374 (rank : 51)
Query Neighborhood Hits	88	Target Neighborhood Hits	570	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

ARHGG_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.006313 (rank : 83)
Query Neighborhood Hits	88	Target Neighborhood Hits	129	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

IFT52_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.011680 (rank : 75)
Query Neighborhood Hits	88	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y366, Q5H8Z0, Q9H1G3, Q9H1G4, Q9H1H2	Gene names	IFT52, C20orf9, NGD5
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 52 homolog (Protein NGD5 homolog).

RAI14_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.009291 (rank : 79)
Query Neighborhood Hits	88	Target Neighborhood Hits	1367	Shared Neighborhood Hits	29
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

AKAP1_HUMAN
θ value	8.99809 (rank : 85)	NC score	0.007533 (rank : 82)
Query Neighborhood Hits	88	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	Q92667, Q13320, Q9BW14	Gene names	AKAP1, AKAP149
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84).

CAH4_MOUSE
θ value	8.99809 (rank : 86)	NC score	0.004127 (rank : 89)
Query Neighborhood Hits	88	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q64444	Gene names	Ca4, Car4
Domain Architecture
Description	Carbonic anhydrase 4 precursor (EC 4.2.1.1) (Carbonic anhydrase IV) (Carbonate dehydratase IV) (CA-IV).

CLH2_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.006204 (rank : 84)
Query Neighborhood Hits	88	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	P53675, Q14017, Q15808, Q15809	Gene names	CLTCL1, CLH22, CLTCL, CLTD
Domain Architecture
Description	Clathrin heavy chain 2 (CLH-22).

RHES_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.002344 (rank : 92)
Query Neighborhood Hits	88	Target Neighborhood Hits	236	Shared Neighborhood Hits	3
SwissProt Accessions	Q96D21, O95520, Q5THY8	Gene names	RASD2, TEM2
Domain Architecture
Description	GTP-binding protein Rhes (Ras homolog enriched in striatum) (Tumor endothelial marker 2).

DAPP1_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.059848 (rank : 35)
Query Neighborhood Hits	88	Target Neighborhood Hits	227	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.059837 (rank : 36)
Query Neighborhood Hits	88	Target Neighborhood Hits	225	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

GAB1_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.101432 (rank : 22)
Query Neighborhood Hits	88	Target Neighborhood Hits	279	Shared Neighborhood Hits	23
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

IRS1_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.066127 (rank : 31)
Query Neighborhood Hits	88	Target Neighborhood Hits	109	Shared Neighborhood Hits	14
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

IRS1_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.064455 (rank : 32)
Query Neighborhood Hits	88	Target Neighborhood Hits	112	Shared Neighborhood Hits	13
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

Hits sorted by NC score

DOC10_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	88	Target Neighborhood Hits	88	Shared Neighborhood Hits	88
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).

DOCK9_MOUSE
NC score	0.978787 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	88	Target Neighborhood Hits	79	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BIK4, Q921Y6	Gene names	Dock9, D14Wsu89e, Kiaa1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

DOCK9_HUMAN
NC score	0.977872 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	88	Target Neighborhood Hits	82	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BZ29, Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26, Q9BZ27, Q9BZ28, Q9UPU4	Gene names	DOCK9, KIAA1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

DOCK7_HUMAN
NC score	0.913205 (rank : 4)	θ value	4.72459e-150 (rank : 4)
Query Neighborhood Hits	88	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q96N67, Q6ZV32, Q8TB82, Q96NG6, Q9C092	Gene names	DOCK7, KIAA1771
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 7.

DOCK6_HUMAN
NC score	0.912800 (rank : 5)	θ value	1.28961e-139 (rank : 5)
Query Neighborhood Hits	88	Target Neighborhood Hits	71	Shared Neighborhood Hits	14
SwissProt Accessions	Q96HP0, Q9P2F2	Gene names	DOCK6, KIAA1395
Domain Architecture
Description	Dedicator of cytokinesis protein 6.

DOCK8_MOUSE
NC score	0.912780 (rank : 6)	θ value	4.58675e-137 (rank : 7)
Query Neighborhood Hits	88	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C147, Q6PIS0, Q7TMQ5, Q8K105, Q9DBQ2	Gene names	Dock8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

DOCK8_HUMAN
NC score	0.901250 (rank : 7)	θ value	3.51195e-137 (rank : 6)
Query Neighborhood Hits	88	Target Neighborhood Hits	42	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NF50, Q3MV16, Q5JPJ1, Q8TEP1, Q8WUY2, Q9BYJ5, Q9H1Q2, Q9H1Q3, Q9H308, Q9H7P2	Gene names	DOCK8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

DOCK3_HUMAN
NC score	0.492703 (rank : 8)	θ value	1.13037e-18 (rank : 8)
Query Neighborhood Hits	88	Target Neighborhood Hits	87	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IZD9, O15017	Gene names	DOCK3, KIAA0299, MOCA
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

DOCK3_MOUSE
NC score	0.492096 (rank : 9)	θ value	3.28887e-18 (rank : 9)
Query Neighborhood Hits	88	Target Neighborhood Hits	93	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CIQ7	Gene names	Dock3, Moca
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

DOCK4_HUMAN
NC score	0.457602 (rank : 10)	θ value	5.8054e-15 (rank : 12)
Query Neighborhood Hits	88	Target Neighborhood Hits	237	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOCK4_MOUSE
NC score	0.456588 (rank : 11)	θ value	9.90251e-15 (rank : 13)
Query Neighborhood Hits	88	Target Neighborhood Hits	210	Shared Neighborhood Hits	17
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOCK2_HUMAN
NC score	0.449803 (rank : 12)	θ value	1.52774e-15 (rank : 11)
Query Neighborhood Hits	88	Target Neighborhood Hits	90	Shared Neighborhood Hits	14
SwissProt Accessions	Q92608, Q96AK7	Gene names	DOCK2, KIAA0209
Domain Architecture
Description	Dedicator of cytokinesis protein 2.

DOCK2_MOUSE
NC score	0.448597 (rank : 13)	θ value	6.85773e-16 (rank : 10)
Query Neighborhood Hits	88	Target Neighborhood Hits	104	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C3J5, Q99M79	Gene names	Dock2
Domain Architecture
Description	Dedicator of cytokinesis protein 2 (Hch protein).

DOCK1_HUMAN
NC score	0.435049 (rank : 14)	θ value	8.38298e-14 (rank : 14)
Query Neighborhood Hits	88	Target Neighborhood Hits	191	Shared Neighborhood Hits	15
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

GAB2_HUMAN
NC score	0.153334 (rank : 15)	θ value	2.44474e-05 (rank : 16)
Query Neighborhood Hits	88	Target Neighborhood Hits	188	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

GAB2_MOUSE
NC score	0.141770 (rank : 16)	θ value	1.69304e-06 (rank : 15)
Query Neighborhood Hits	88	Target Neighborhood Hits	220	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

GAB1_MOUSE
NC score	0.121136 (rank : 17)	θ value	0.0148317 (rank : 22)
Query Neighborhood Hits	88	Target Neighborhood Hits	233	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

RHG25_HUMAN
NC score	0.115310 (rank : 18)	θ value	7.1131e-05 (rank : 17)
Query Neighborhood Hits	88	Target Neighborhood Hits	550	Shared Neighborhood Hits	36
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

PKHA6_MOUSE
NC score	0.111351 (rank : 19)	θ value	0.0563607 (rank : 25)
Query Neighborhood Hits	88	Target Neighborhood Hits	591	Shared Neighborhood Hits	35
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA5_HUMAN
NC score	0.105218 (rank : 20)	θ value	0.0431538 (rank : 23)
Query Neighborhood Hits	88	Target Neighborhood Hits	455	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

RHG25_MOUSE
NC score	0.103007 (rank : 21)	θ value	0.00035302 (rank : 18)
Query Neighborhood Hits	88	Target Neighborhood Hits	492	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

GAB1_HUMAN
NC score	0.101432 (rank : 22)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	88	Target Neighborhood Hits	279	Shared Neighborhood Hits	23
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

PKHA4_MOUSE
NC score	0.095333 (rank : 23)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	88	Target Neighborhood Hits	202	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PLEK_HUMAN
NC score	0.090924 (rank : 24)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	88	Target Neighborhood Hits	110	Shared Neighborhood Hits	27
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PKHA4_HUMAN
NC score	0.088553 (rank : 25)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	88	Target Neighborhood Hits	283	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PLEK_MOUSE
NC score	0.077407 (rank : 26)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	88	Target Neighborhood Hits	109	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

PLEK2_HUMAN
NC score	0.075688 (rank : 27)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	88	Target Neighborhood Hits	101	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_MOUSE
NC score	0.069338 (rank : 28)	θ value	0.62314 (rank : 35)
Query Neighborhood Hits	88	Target Neighborhood Hits	96	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PKHA6_HUMAN
NC score	0.069328 (rank : 29)	θ value	0.163984 (rank : 27)
Query Neighborhood Hits	88	Target Neighborhood Hits	556	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA1_HUMAN
NC score	0.068728 (rank : 30)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	88	Target Neighborhood Hits	127	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

IRS1_HUMAN
NC score	0.066127 (rank : 31)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	88	Target Neighborhood Hits	109	Shared Neighborhood Hits	14
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

IRS1_MOUSE
NC score	0.064455 (rank : 32)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	88	Target Neighborhood Hits	112	Shared Neighborhood Hits	13
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

TARA_MOUSE
NC score	0.063153 (rank : 33)	θ value	0.00869519 (rank : 21)
Query Neighborhood Hits	88	Target Neighborhood Hits	1133	Shared Neighborhood Hits	38
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

PKHA1_MOUSE
NC score	0.060557 (rank : 34)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	88	Target Neighborhood Hits	120	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

DAPP1_HUMAN
NC score	0.059848 (rank : 35)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	88	Target Neighborhood Hits	227	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
NC score	0.059837 (rank : 36)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	88	Target Neighborhood Hits	225	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

MRIP_MOUSE
NC score	0.056249 (rank : 37)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	88	Target Neighborhood Hits	569	Shared Neighborhood Hits	36
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

MRIP_HUMAN
NC score	0.055975 (rank : 38)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	88	Target Neighborhood Hits	578	Shared Neighborhood Hits	34
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

TARA_HUMAN
NC score	0.050195 (rank : 39)	θ value	0.00509761 (rank : 20)
Query Neighborhood Hits	88	Target Neighborhood Hits	1626	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CNKR1_HUMAN
NC score	0.047415 (rank : 40)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	88	Target Neighborhood Hits	154	Shared Neighborhood Hits	19
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

NU107_HUMAN
NC score	0.044035 (rank : 41)	θ value	0.21417 (rank : 30)
Query Neighborhood Hits	88	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	P57740	Gene names	NUP107
Domain Architecture
Description	Nuclear pore complex protein Nup107 (Nucleoporin Nup107) (107 kDa nucleoporin).

NU107_MOUSE
NC score	0.038416 (rank : 42)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	88	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BH74, Q99KH5	Gene names	Nup107
Domain Architecture
Description	Nuclear pore complex protein Nup107 (Nucleoporin Nup107) (107 kDa nucleoporin).

SPTN2_HUMAN
NC score	0.031854 (rank : 43)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	88	Target Neighborhood Hits	535	Shared Neighborhood Hits	24
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

MYO10_HUMAN
NC score	0.031343 (rank : 44)	θ value	0.00175202 (rank : 19)
Query Neighborhood Hits	88	Target Neighborhood Hits	920	Shared Neighborhood Hits	36
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

IRS2_MOUSE
NC score	0.030170 (rank : 45)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	88	Target Neighborhood Hits	248	Shared Neighborhood Hits	10
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

IRS2_HUMAN
NC score	0.028041 (rank : 46)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	88	Target Neighborhood Hits	262	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

SPTB2_HUMAN
NC score	0.026853 (rank : 47)	θ value	1.06291 (rank : 42)
Query Neighborhood Hits	88	Target Neighborhood Hits	748	Shared Neighborhood Hits	32
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTB2_MOUSE
NC score	0.025709 (rank : 48)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	88	Target Neighborhood Hits	770	Shared Neighborhood Hits	32
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

GOGB1_HUMAN
NC score	0.025478 (rank : 49)	θ value	0.0563607 (rank : 24)
Query Neighborhood Hits	88	Target Neighborhood Hits	2297	Shared Neighborhood Hits	37
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

IFT81_MOUSE
NC score	0.024687 (rank : 50)	θ value	0.21417 (rank : 29)
Query Neighborhood Hits	88	Target Neighborhood Hits	959	Shared Neighborhood Hits	26
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

SPTN4_HUMAN
NC score	0.024374 (rank : 51)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	88	Target Neighborhood Hits	570	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

RPC1_HUMAN
NC score	0.023881 (rank : 52)	θ value	0.47712 (rank : 32)
Query Neighborhood Hits	88	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	O14802, Q8TCW5	Gene names	POLR3A
Domain Architecture
Description	DNA-directed RNA polymerase III largest subunit (EC 2.7.7.6) (RPC155) (RPC1).

DP13A_HUMAN
NC score	0.023818 (rank : 53)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	88	Target Neighborhood Hits	107	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKG1, Q9P2B9	Gene names	APPL1, APPL, DIP13A, KIAA1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

DP13A_MOUSE
NC score	0.023577 (rank : 54)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	88	Target Neighborhood Hits	96	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K3H0, Q3UJP7, Q69ZJ9, Q8BWZ8, Q8VCJ8, Q9CUW4	Gene names	Appl1, Dip13a, Kiaa1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

IFT81_HUMAN
NC score	0.022814 (rank : 55)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	88	Target Neighborhood Hits	893	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

AKA11_HUMAN
NC score	0.022741 (rank : 56)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	88	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKA4, O75124, Q9NUK7	Gene names	AKAP11, AKAP220, KIAA0629
Domain Architecture
Description	A-kinase anchor protein 11 (Protein kinase A-anchoring protein 11) (PRKA11) (A kinase anchor protein 220 kDa) (AKAP 220) (hAKAP220).

HMMR_HUMAN
NC score	0.022247 (rank : 57)	θ value	0.163984 (rank : 26)
Query Neighborhood Hits	88	Target Neighborhood Hits	1082	Shared Neighborhood Hits	25
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

PLCG1_MOUSE
NC score	0.021859 (rank : 58)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	88	Target Neighborhood Hits	314	Shared Neighborhood Hits	8
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

GOGA1_HUMAN
NC score	0.021429 (rank : 59)	θ value	0.21417 (rank : 28)
Query Neighborhood Hits	88	Target Neighborhood Hits	1222	Shared Neighborhood Hits	28
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GOGA4_HUMAN
NC score	0.019580 (rank : 60)	θ value	0.365318 (rank : 31)
Query Neighborhood Hits	88	Target Neighborhood Hits	2034	Shared Neighborhood Hits	35
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

AKAP9_HUMAN
NC score	0.019250 (rank : 61)	θ value	0.813845 (rank : 36)
Query Neighborhood Hits	88	Target Neighborhood Hits	1710	Shared Neighborhood Hits	35
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

ARK72_HUMAN
NC score	0.017446 (rank : 62)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	88	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	O43488, O75749, Q5TG63	Gene names	AKR7A2, AFAR, AFAR1, AKR7
Domain Architecture
Description	Aflatoxin B1 aldehyde reductase member 2 (EC 1.-.-.-) (AFB1-AR 1) (Aldoketoreductase 7).

NEB2_MOUSE
NC score	0.017333 (rank : 63)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	88	Target Neighborhood Hits	889	Shared Neighborhood Hits	24
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

PLCG1_HUMAN
NC score	0.016974 (rank : 64)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	88	Target Neighborhood Hits	293	Shared Neighborhood Hits	7
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

NEB2_HUMAN
NC score	0.015863 (rank : 65)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	88	Target Neighborhood Hits	883	Shared Neighborhood Hits	24
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

ARK72_MOUSE
NC score	0.015388 (rank : 66)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	88	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CG76, Q3UPU2, Q8CG77, Q8JZQ8, Q9D157	Gene names	Akr7a2, Afar, Akr7a5
Domain Architecture
Description	Aflatoxin B1 aldehyde reductase member 2 (EC 1.-.-.-).

CTNA2_MOUSE
NC score	0.014626 (rank : 67)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	88	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	Q61301, Q61300, Q6AXD1	Gene names	Ctnna2, Catna2
Domain Architecture
Description	Catenin alpha-2 (Alpha-catenin-related protein) (Alpha N-catenin).

CTNA2_HUMAN
NC score	0.014617 (rank : 68)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	88	Target Neighborhood Hits	74	Shared Neighborhood Hits	9
SwissProt Accessions	P26232, Q4ZFW1, Q53R26, Q53R33, Q53T67, Q53T71, Q53TM8, Q7Z3Y0	Gene names	CTNNA2, CAPR
Domain Architecture
Description	Catenin alpha-2 (Alpha-catenin-related protein) (Alpha N-catenin).

TRI14_HUMAN
NC score	0.014299 (rank : 69)	θ value	1.06291 (rank : 43)
Query Neighborhood Hits	88	Target Neighborhood Hits	143	Shared Neighborhood Hits	3
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

CENPE_HUMAN
NC score	0.014002 (rank : 70)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	88	Target Neighborhood Hits	2060	Shared Neighborhood Hits	37
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

TTC7A_HUMAN
NC score	0.013435 (rank : 71)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	88	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULT0, Q6PIX4, Q8ND67, Q9BUS3	Gene names	TTC7A, KIAA1140, TTC7
Domain Architecture
Description	Tetratricopeptide repeat protein 7A (TPR repeat protein 7).

LAMB1_HUMAN
NC score	0.013276 (rank : 72)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	88	Target Neighborhood Hits	1018	Shared Neighborhood Hits	20
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB1_MOUSE
NC score	0.012900 (rank : 73)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	88	Target Neighborhood Hits	919	Shared Neighborhood Hits	21
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

TRI14_MOUSE
NC score	0.012558 (rank : 74)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	88	Target Neighborhood Hits	137	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

IFT52_HUMAN
NC score	0.011680 (rank : 75)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	88	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y366, Q5H8Z0, Q9H1G3, Q9H1G4, Q9H1H2	Gene names	IFT52, C20orf9, NGD5
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 52 homolog (Protein NGD5 homolog).

DMXL1_HUMAN
NC score	0.009986 (rank : 76)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	88	Target Neighborhood Hits	259	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y485	Gene names	DMXL1, XL1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

MPP2_MOUSE
NC score	0.009698 (rank : 77)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	88	Target Neighborhood Hits	189	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

CALR3_MOUSE
NC score	0.009429 (rank : 78)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	88	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D9Q6	Gene names	Calr3, Crt2
Domain Architecture
Description	Calreticulin-3 precursor (Calreticulin-2).

RAI14_HUMAN
NC score	0.009291 (rank : 79)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	88	Target Neighborhood Hits	1367	Shared Neighborhood Hits	29
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

SIRT1_MOUSE
NC score	0.009194 (rank : 80)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	88	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q923E4, Q9QXG8	Gene names	Sirt1, Sir2l1
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-1 (EC 3.5.1.-) (SIR2alpha) (mSIR2a) (Sir2) (SIR2-like protein 1).

ACOX3_MOUSE
NC score	0.009015 (rank : 81)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	88	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EPL9	Gene names	Acox3
Domain Architecture
Description	Acyl-coenzyme A oxidase 3, peroxisomal (EC 1.3.3.6) (Pristanoyl-CoA oxidase) (Branched-chain acyl-CoA oxidase) (BRCACox).

AKAP1_HUMAN
NC score	0.007533 (rank : 82)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	88	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	Q92667, Q13320, Q9BW14	Gene names	AKAP1, AKAP149
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84).

ARHGG_HUMAN
NC score	0.006313 (rank : 83)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	88	Target Neighborhood Hits	129	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

CLH2_HUMAN
NC score	0.006204 (rank : 84)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	88	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	P53675, Q14017, Q15808, Q15809	Gene names	CLTCL1, CLH22, CLTCL, CLTD
Domain Architecture
Description	Clathrin heavy chain 2 (CLH-22).

K2C6B_HUMAN
NC score	0.005661 (rank : 85)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	88	Target Neighborhood Hits	526	Shared Neighborhood Hits	18
SwissProt Accessions	P04259, P48669	Gene names	KRT6B, K6B
Domain Architecture
Description	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin).

K2C6E_HUMAN
NC score	0.005597 (rank : 86)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	88	Target Neighborhood Hits	516	Shared Neighborhood Hits	16
SwissProt Accessions	P48668, Q7RTN9	Gene names	KRT6E
Domain Architecture
Description	Keratin, type II cytoskeletal 6E (Cytokeratin-6E) (CK 6E) (K6e keratin) (Keratin K6h).

ACHB2_HUMAN
NC score	0.004764 (rank : 87)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	88	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	P17787, Q9UEH9	Gene names	CHRNB2
Domain Architecture
Description	Neuronal acetylcholine receptor protein subunit beta-2 precursor.

ACHB2_MOUSE
NC score	0.004755 (rank : 88)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	88	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ERK7	Gene names	Chrnb2
Domain Architecture	No domain graphic available
Description	Neuronal acetylcholine receptor protein subunit beta-2 precursor.

CAH4_MOUSE
NC score	0.004127 (rank : 89)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	88	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q64444	Gene names	Ca4, Car4
Domain Architecture
Description	Carbonic anhydrase 4 precursor (EC 4.2.1.1) (Carbonic anhydrase IV) (Carbonate dehydratase IV) (CA-IV).

MRCKA_HUMAN
NC score	0.004122 (rank : 90)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	88	Target Neighborhood Hits	1999	Shared Neighborhood Hits	30
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

RHES_MOUSE
NC score	0.003279 (rank : 91)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	88	Target Neighborhood Hits	236	Shared Neighborhood Hits	3
SwissProt Accessions	P63032, Q9WVD3	Gene names	Rasd2
Domain Architecture	No domain graphic available
Description	GTP-binding protein Rhes (Ras homolog enriched in striatum).

RHES_HUMAN
NC score	0.002344 (rank : 92)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	88	Target Neighborhood Hits	236	Shared Neighborhood Hits	3
SwissProt Accessions	Q96D21, O95520, Q5THY8	Gene names	RASD2, TEM2
Domain Architecture
Description	GTP-binding protein Rhes (Ras homolog enriched in striatum) (Tumor endothelial marker 2).

FAK2_MOUSE
NC score	-0.000228 (rank : 93)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	88	Target Neighborhood Hits	851	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).