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Network neighborhood for query Sequence : CLH2_HUMAN

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CLH2_HUMAN
SwissProt Accessions	P53675, Q14017, Q15808, Q15809	Gene names	CLTCL1, CLH22, CLTCL, CLTD
Domain Architecture
Description	Clathrin heavy chain 2 (CLH-22).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CLH1_HUMAN
θ value	0 (rank : 1)	NC score	0.995191 (rank : 2)
Query Neighborhood Hits	39	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q00610, Q6N0A0, Q86TF2	Gene names	CLTC, CLH17, KIAA0034
Domain Architecture
Description	Clathrin heavy chain 1 (CLH-17).

CLH2_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	39	Target Neighborhood Hits	39	Shared Neighborhood Hits	39
SwissProt Accessions	P53675, Q14017, Q15808, Q15809	Gene names	CLTCL1, CLH22, CLTCL, CLTD
Domain Architecture
Description	Clathrin heavy chain 2 (CLH-22).

CLH_MOUSE
θ value	0 (rank : 3)	NC score	0.995003 (rank : 3)
Query Neighborhood Hits	39	Target Neighborhood Hits	36	Shared Neighborhood Hits	14
SwissProt Accessions	Q68FD5	Gene names	Cltc
Domain Architecture	No domain graphic available
Description	Clathrin heavy chain.

VAV_HUMAN
θ value	0.0193708 (rank : 4)	NC score	0.022927 (rank : 15)
Query Neighborhood Hits	39	Target Neighborhood Hits	452	Shared Neighborhood Hits	2
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VPS41_HUMAN
θ value	0.163984 (rank : 5)	NC score	0.095128 (rank : 5)
Query Neighborhood Hits	39	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	P49754, Q99851, Q99852	Gene names	VPS41
Domain Architecture
Description	Vacuolar protein sorting-associated protein 41 homolog (S53).

VPS41_MOUSE
θ value	0.163984 (rank : 6)	NC score	0.095262 (rank : 4)
Query Neighborhood Hits	39	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	Q5KU39, Q3TPS1, Q80V99, Q8BKK6, Q8CG01, Q8CJC3	Gene names	Vps41
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 41 homolog (VAM2 homolog) (mVAM2).

WDR35_MOUSE
θ value	0.47712 (rank : 7)	NC score	0.057483 (rank : 7)
Query Neighborhood Hits	39	Target Neighborhood Hits	126	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BND3, Q8CDL4	Gene names	Wdr35
Domain Architecture
Description	WD repeat protein 35.

ANLN_MOUSE
θ value	0.813845 (rank : 8)	NC score	0.026768 (rank : 8)
Query Neighborhood Hits	39	Target Neighborhood Hits	297	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

KCC1D_HUMAN
θ value	0.813845 (rank : 9)	NC score	0.004054 (rank : 38)
Query Neighborhood Hits	39	Target Neighborhood Hits	846	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IU85, Q9HD31	Gene names	CAMK1D
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK).

KCC1D_MOUSE
θ value	0.813845 (rank : 10)	NC score	0.004055 (rank : 37)
Query Neighborhood Hits	39	Target Neighborhood Hits	847	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BW96, Q3U450, Q80W64, Q8BWI7	Gene names	Camk1d
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) (mCKLiK).

SYNE1_HUMAN
θ value	1.38821 (rank : 11)	NC score	0.013504 (rank : 21)
Query Neighborhood Hits	39	Target Neighborhood Hits	1484	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

DHX57_HUMAN
θ value	1.81305 (rank : 12)	NC score	0.011660 (rank : 23)
Query Neighborhood Hits	39	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

I2C2_HUMAN
θ value	2.36792 (rank : 13)	NC score	0.023399 (rank : 12)
Query Neighborhood Hits	39	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKV8, Q8TCZ5, Q8WV58, Q96ID1	Gene names	EIF2C2, AGO2
Domain Architecture
Description	Eukaryotic translation initiation factor 2C 2 (eIF2C 2) (eIF-2C 2) (Argonaute-2) (Slicer protein) (PAZ Piwi domain protein) (PPD).

I2C2_MOUSE
θ value	2.36792 (rank : 14)	NC score	0.023240 (rank : 13)
Query Neighborhood Hits	39	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CJG0, Q4VAB3, Q571J6	Gene names	Eif2c2, Ago2, Kiaa4215
Domain Architecture
Description	Eukaryotic translation initiation factor 2C 2 (eIF2C 2) (eIF-2C 2) (Argonaute-2) (Slicer protein) (Piwi/argonaute family protein meIF2C2).

BSSP4_HUMAN
θ value	3.0926 (rank : 15)	NC score	0.004932 (rank : 36)
Query Neighborhood Hits	39	Target Neighborhood Hits	176	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZN4, O43342, Q6UXE0	Gene names	PRSS22, BSSP4, PRSS26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

DOC2A_HUMAN
θ value	3.0926 (rank : 16)	NC score	0.007498 (rank : 31)
Query Neighborhood Hits	39	Target Neighborhood Hits	144	Shared Neighborhood Hits	2
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

CSN2_HUMAN
θ value	4.03905 (rank : 17)	NC score	0.025089 (rank : 10)
Query Neighborhood Hits	39	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	P61201, O88950, Q15647, Q6FGP4, Q9BY54, Q9R249, Q9UNI2, Q9UNQ5	Gene names	COPS2, CSN2, TRIP15
Domain Architecture
Description	COP9 signalosome complex subunit 2 (Signalosome subunit 2) (SGN2) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (Alien homolog).

CSN2_MOUSE
θ value	4.03905 (rank : 18)	NC score	0.025089 (rank : 11)
Query Neighborhood Hits	39	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	P61202, O88950, Q15647, Q3V1W6, Q8R5B0, Q9CWU1, Q9R249, Q9UNQ5	Gene names	Cops2, Csn2, Trip15
Domain Architecture
Description	COP9 signalosome complex subunit 2 (Signalosome subunit 2) (SGN2) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (Alien homolog).

LRMP_MOUSE
θ value	4.03905 (rank : 19)	NC score	0.025162 (rank : 9)
Query Neighborhood Hits	39	Target Neighborhood Hits	120	Shared Neighborhood Hits	3
SwissProt Accessions	Q60664, Q7TMU8	Gene names	Lrmp, Jaw1
Domain Architecture	No domain graphic available
Description	Lymphoid-restricted membrane protein (Protein Jaw1).

LRMP_HUMAN
θ value	5.27518 (rank : 20)	NC score	0.023093 (rank : 14)
Query Neighborhood Hits	39	Target Neighborhood Hits	126	Shared Neighborhood Hits	4
SwissProt Accessions	Q12912, Q8N301	Gene names	LRMP, JAW1
Domain Architecture	No domain graphic available
Description	Lymphoid-restricted membrane protein (Protein Jaw1).

NRP1_MOUSE
θ value	5.27518 (rank : 21)	NC score	0.016977 (rank : 16)
Query Neighborhood Hits	39	Target Neighborhood Hits	120	Shared Neighborhood Hits	5
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

UBP7_HUMAN
θ value	5.27518 (rank : 22)	NC score	0.009634 (rank : 28)
Query Neighborhood Hits	39	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

1433B_HUMAN
θ value	6.88961 (rank : 23)	NC score	0.015954 (rank : 19)
Query Neighborhood Hits	39	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	P31946	Gene names	YWHAB
Domain Architecture
Description	14-3-3 protein beta/alpha (Protein kinase C inhibitor protein 1) (KCIP-1) (Protein 1054).

ABTB1_HUMAN
θ value	6.88961 (rank : 24)	NC score	0.006962 (rank : 34)
Query Neighborhood Hits	39	Target Neighborhood Hits	325	Shared Neighborhood Hits	2
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

BSSP4_MOUSE
θ value	6.88961 (rank : 25)	NC score	0.007706 (rank : 30)
Query Neighborhood Hits	39	Target Neighborhood Hits	179	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ER10	Gene names	Prss22, Bssp4, Prss26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

CRNL1_MOUSE
θ value	6.88961 (rank : 26)	NC score	0.011384 (rank : 26)
Query Neighborhood Hits	39	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	P63154, Q542E8, Q9CQC1	Gene names	Crnkl1
Domain Architecture	No domain graphic available
Description	Crooked neck-like protein 1 (Crooked neck homolog).

ZC11A_MOUSE
θ value	6.88961 (rank : 27)	NC score	0.011828 (rank : 22)
Query Neighborhood Hits	39	Target Neighborhood Hits	216	Shared Neighborhood Hits	2
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

DMAP1_HUMAN
θ value	8.99809 (rank : 28)	NC score	0.016429 (rank : 18)
Query Neighborhood Hits	39	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NPF5, Q5TG41, Q7Z3H7, Q9H0S8, Q9P2C2	Gene names	DMAP1, KIAA1425
Domain Architecture
Description	DNA methyltransferase 1-associated protein 1 (DNMT1-associated protein 1) (DNMAP1).

DMAP1_MOUSE
θ value	8.99809 (rank : 29)	NC score	0.016447 (rank : 17)
Query Neighborhood Hits	39	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JI44, Q99LM0, Q9CSS9, Q9DB33	Gene names	Dmap1, Mmtr
Domain Architecture
Description	DNA methyltransferase 1-associated protein 1 (DNMT1-associated protein 1) (DNMAP1) (MAT1-mediated transcriptional repressor).

DOC10_HUMAN
θ value	8.99809 (rank : 30)	NC score	0.006204 (rank : 35)
Query Neighborhood Hits	39	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).

K1HB_HUMAN
θ value	8.99809 (rank : 31)	NC score	0.001755 (rank : 39)
Query Neighborhood Hits	39	Target Neighborhood Hits	470	Shared Neighborhood Hits	3
SwissProt Accessions	Q14525, O76010	Gene names	KRTHA3B, HHA3-II, HKA3B
Domain Architecture
Description	Keratin, type I cuticular Ha3-II (Hair keratin, type I Ha3-II).

NOC4L_MOUSE
θ value	8.99809 (rank : 32)	NC score	0.011532 (rank : 24)
Query Neighborhood Hits	39	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BHY2, Q8R1F7	Gene names	Noc4l
Domain Architecture	No domain graphic available
Description	Nucleolar complex protein 4 homolog (NOC4 protein homolog) (NOC4-like protein) (Nucleolar complex-associated protein 4-like protein).

NRP1_HUMAN
θ value	8.99809 (rank : 33)	NC score	0.013805 (rank : 20)
Query Neighborhood Hits	39	Target Neighborhood Hits	119	Shared Neighborhood Hits	5
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

PRKDC_HUMAN
θ value	8.99809 (rank : 34)	NC score	0.007181 (rank : 32)
Query Neighborhood Hits	39	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3	Gene names	PRKDC
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460).

TAF1L_HUMAN
θ value	8.99809 (rank : 35)	NC score	0.011422 (rank : 25)
Query Neighborhood Hits	39	Target Neighborhood Hits	144	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZX4	Gene names	TAF1L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID 210 kDa subunit (TBP-associated factor 210 kDa) (TAF(II)210) (TBP-associated factor 1-like).

TAF1_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.011267 (rank : 27)
Query Neighborhood Hits	39	Target Neighborhood Hits	136	Shared Neighborhood Hits	3
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

TRAP1_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.007744 (rank : 29)
Query Neighborhood Hits	39	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q12931, O43642, O75235, Q9UHL5	Gene names	TRAP1, HSP75
Domain Architecture
Description	Heat shock protein 75 kDa, mitochondrial precursor (HSP 75) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) (TNFR- associated protein 1).

WDR35_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.063374 (rank : 6)
Query Neighborhood Hits	39	Target Neighborhood Hits	132	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P2L0, Q8NE11	Gene names	WDR35, KIAA1336
Domain Architecture
Description	WD repeat protein 35.

ZFYV9_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.007175 (rank : 33)
Query Neighborhood Hits	39	Target Neighborhood Hits	134	Shared Neighborhood Hits	2
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

Hits sorted by NC score

CLH2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	39	Target Neighborhood Hits	39	Shared Neighborhood Hits	39
SwissProt Accessions	P53675, Q14017, Q15808, Q15809	Gene names	CLTCL1, CLH22, CLTCL, CLTD
Domain Architecture
Description	Clathrin heavy chain 2 (CLH-22).

CLH1_HUMAN
NC score	0.995191 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	39	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q00610, Q6N0A0, Q86TF2	Gene names	CLTC, CLH17, KIAA0034
Domain Architecture
Description	Clathrin heavy chain 1 (CLH-17).

CLH_MOUSE
NC score	0.995003 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	39	Target Neighborhood Hits	36	Shared Neighborhood Hits	14
SwissProt Accessions	Q68FD5	Gene names	Cltc
Domain Architecture	No domain graphic available
Description	Clathrin heavy chain.

VPS41_MOUSE
NC score	0.095262 (rank : 4)	θ value	0.163984 (rank : 6)
Query Neighborhood Hits	39	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	Q5KU39, Q3TPS1, Q80V99, Q8BKK6, Q8CG01, Q8CJC3	Gene names	Vps41
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 41 homolog (VAM2 homolog) (mVAM2).

VPS41_HUMAN
NC score	0.095128 (rank : 5)	θ value	0.163984 (rank : 5)
Query Neighborhood Hits	39	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	P49754, Q99851, Q99852	Gene names	VPS41
Domain Architecture
Description	Vacuolar protein sorting-associated protein 41 homolog (S53).

WDR35_HUMAN
NC score	0.063374 (rank : 6)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	39	Target Neighborhood Hits	132	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P2L0, Q8NE11	Gene names	WDR35, KIAA1336
Domain Architecture
Description	WD repeat protein 35.

WDR35_MOUSE
NC score	0.057483 (rank : 7)	θ value	0.47712 (rank : 7)
Query Neighborhood Hits	39	Target Neighborhood Hits	126	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BND3, Q8CDL4	Gene names	Wdr35
Domain Architecture
Description	WD repeat protein 35.

ANLN_MOUSE
NC score	0.026768 (rank : 8)	θ value	0.813845 (rank : 8)
Query Neighborhood Hits	39	Target Neighborhood Hits	297	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

LRMP_MOUSE
NC score	0.025162 (rank : 9)	θ value	4.03905 (rank : 19)
Query Neighborhood Hits	39	Target Neighborhood Hits	120	Shared Neighborhood Hits	3
SwissProt Accessions	Q60664, Q7TMU8	Gene names	Lrmp, Jaw1
Domain Architecture	No domain graphic available
Description	Lymphoid-restricted membrane protein (Protein Jaw1).

CSN2_HUMAN
NC score	0.025089 (rank : 10)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	39	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	P61201, O88950, Q15647, Q6FGP4, Q9BY54, Q9R249, Q9UNI2, Q9UNQ5	Gene names	COPS2, CSN2, TRIP15
Domain Architecture
Description	COP9 signalosome complex subunit 2 (Signalosome subunit 2) (SGN2) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (Alien homolog).

CSN2_MOUSE
NC score	0.025089 (rank : 11)	θ value	4.03905 (rank : 18)
Query Neighborhood Hits	39	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	P61202, O88950, Q15647, Q3V1W6, Q8R5B0, Q9CWU1, Q9R249, Q9UNQ5	Gene names	Cops2, Csn2, Trip15
Domain Architecture
Description	COP9 signalosome complex subunit 2 (Signalosome subunit 2) (SGN2) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (Alien homolog).

I2C2_HUMAN
NC score	0.023399 (rank : 12)	θ value	2.36792 (rank : 13)
Query Neighborhood Hits	39	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKV8, Q8TCZ5, Q8WV58, Q96ID1	Gene names	EIF2C2, AGO2
Domain Architecture
Description	Eukaryotic translation initiation factor 2C 2 (eIF2C 2) (eIF-2C 2) (Argonaute-2) (Slicer protein) (PAZ Piwi domain protein) (PPD).

I2C2_MOUSE
NC score	0.023240 (rank : 13)	θ value	2.36792 (rank : 14)
Query Neighborhood Hits	39	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CJG0, Q4VAB3, Q571J6	Gene names	Eif2c2, Ago2, Kiaa4215
Domain Architecture
Description	Eukaryotic translation initiation factor 2C 2 (eIF2C 2) (eIF-2C 2) (Argonaute-2) (Slicer protein) (Piwi/argonaute family protein meIF2C2).

LRMP_HUMAN
NC score	0.023093 (rank : 14)	θ value	5.27518 (rank : 20)
Query Neighborhood Hits	39	Target Neighborhood Hits	126	Shared Neighborhood Hits	4
SwissProt Accessions	Q12912, Q8N301	Gene names	LRMP, JAW1
Domain Architecture	No domain graphic available
Description	Lymphoid-restricted membrane protein (Protein Jaw1).

VAV_HUMAN
NC score	0.022927 (rank : 15)	θ value	0.0193708 (rank : 4)
Query Neighborhood Hits	39	Target Neighborhood Hits	452	Shared Neighborhood Hits	2
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

NRP1_MOUSE
NC score	0.016977 (rank : 16)	θ value	5.27518 (rank : 21)
Query Neighborhood Hits	39	Target Neighborhood Hits	120	Shared Neighborhood Hits	5
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

DMAP1_MOUSE
NC score	0.016447 (rank : 17)	θ value	8.99809 (rank : 29)
Query Neighborhood Hits	39	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JI44, Q99LM0, Q9CSS9, Q9DB33	Gene names	Dmap1, Mmtr
Domain Architecture
Description	DNA methyltransferase 1-associated protein 1 (DNMT1-associated protein 1) (DNMAP1) (MAT1-mediated transcriptional repressor).

DMAP1_HUMAN
NC score	0.016429 (rank : 18)	θ value	8.99809 (rank : 28)
Query Neighborhood Hits	39	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NPF5, Q5TG41, Q7Z3H7, Q9H0S8, Q9P2C2	Gene names	DMAP1, KIAA1425
Domain Architecture
Description	DNA methyltransferase 1-associated protein 1 (DNMT1-associated protein 1) (DNMAP1).

1433B_HUMAN
NC score	0.015954 (rank : 19)	θ value	6.88961 (rank : 23)
Query Neighborhood Hits	39	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	P31946	Gene names	YWHAB
Domain Architecture
Description	14-3-3 protein beta/alpha (Protein kinase C inhibitor protein 1) (KCIP-1) (Protein 1054).

NRP1_HUMAN
NC score	0.013805 (rank : 20)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	39	Target Neighborhood Hits	119	Shared Neighborhood Hits	5
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

SYNE1_HUMAN
NC score	0.013504 (rank : 21)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	39	Target Neighborhood Hits	1484	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

ZC11A_MOUSE
NC score	0.011828 (rank : 22)	θ value	6.88961 (rank : 27)
Query Neighborhood Hits	39	Target Neighborhood Hits	216	Shared Neighborhood Hits	2
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

DHX57_HUMAN
NC score	0.011660 (rank : 23)	θ value	1.81305 (rank : 12)
Query Neighborhood Hits	39	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

NOC4L_MOUSE
NC score	0.011532 (rank : 24)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	39	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BHY2, Q8R1F7	Gene names	Noc4l
Domain Architecture	No domain graphic available
Description	Nucleolar complex protein 4 homolog (NOC4 protein homolog) (NOC4-like protein) (Nucleolar complex-associated protein 4-like protein).

TAF1L_HUMAN
NC score	0.011422 (rank : 25)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	39	Target Neighborhood Hits	144	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZX4	Gene names	TAF1L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID 210 kDa subunit (TBP-associated factor 210 kDa) (TAF(II)210) (TBP-associated factor 1-like).

CRNL1_MOUSE
NC score	0.011384 (rank : 26)	θ value	6.88961 (rank : 26)
Query Neighborhood Hits	39	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	P63154, Q542E8, Q9CQC1	Gene names	Crnkl1
Domain Architecture	No domain graphic available
Description	Crooked neck-like protein 1 (Crooked neck homolog).

TAF1_HUMAN
NC score	0.011267 (rank : 27)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	39	Target Neighborhood Hits	136	Shared Neighborhood Hits	3
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

UBP7_HUMAN
NC score	0.009634 (rank : 28)	θ value	5.27518 (rank : 22)
Query Neighborhood Hits	39	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

TRAP1_HUMAN
NC score	0.007744 (rank : 29)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	39	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q12931, O43642, O75235, Q9UHL5	Gene names	TRAP1, HSP75
Domain Architecture
Description	Heat shock protein 75 kDa, mitochondrial precursor (HSP 75) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) (TNFR- associated protein 1).

BSSP4_MOUSE
NC score	0.007706 (rank : 30)	θ value	6.88961 (rank : 25)
Query Neighborhood Hits	39	Target Neighborhood Hits	179	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ER10	Gene names	Prss22, Bssp4, Prss26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

DOC2A_HUMAN
NC score	0.007498 (rank : 31)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	39	Target Neighborhood Hits	144	Shared Neighborhood Hits	2
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

PRKDC_HUMAN
NC score	0.007181 (rank : 32)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	39	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3	Gene names	PRKDC
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460).

ZFYV9_HUMAN
NC score	0.007175 (rank : 33)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	39	Target Neighborhood Hits	134	Shared Neighborhood Hits	2
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

ABTB1_HUMAN
NC score	0.006962 (rank : 34)	θ value	6.88961 (rank : 24)
Query Neighborhood Hits	39	Target Neighborhood Hits	325	Shared Neighborhood Hits	2
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

DOC10_HUMAN
NC score	0.006204 (rank : 35)	θ value	8.99809 (rank : 30)
Query Neighborhood Hits	39	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).

BSSP4_HUMAN
NC score	0.004932 (rank : 36)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	39	Target Neighborhood Hits	176	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZN4, O43342, Q6UXE0	Gene names	PRSS22, BSSP4, PRSS26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

KCC1D_MOUSE
NC score	0.004055 (rank : 37)	θ value	0.813845 (rank : 10)
Query Neighborhood Hits	39	Target Neighborhood Hits	847	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BW96, Q3U450, Q80W64, Q8BWI7	Gene names	Camk1d
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) (mCKLiK).

KCC1D_HUMAN
NC score	0.004054 (rank : 38)	θ value	0.813845 (rank : 9)
Query Neighborhood Hits	39	Target Neighborhood Hits	846	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IU85, Q9HD31	Gene names	CAMK1D
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase type 1D (EC 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK).

K1HB_HUMAN
NC score	0.001755 (rank : 39)	θ value	8.99809 (rank : 31)
Query Neighborhood Hits	39	Target Neighborhood Hits	470	Shared Neighborhood Hits	3
SwissProt Accessions	Q14525, O76010	Gene names	KRTHA3B, HHA3-II, HKA3B
Domain Architecture
Description	Keratin, type I cuticular Ha3-II (Hair keratin, type I Ha3-II).