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Network neighborhood for query Sequence : IRS1_HUMAN

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IRS1_HUMAN
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IRS1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	109
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

IRS1_MOUSE
θ value	0 (rank : 2)	NC score	0.981650 (rank : 2)
Query Neighborhood Hits	109	Target Neighborhood Hits	112	Shared Neighborhood Hits	62
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

IRS2_MOUSE
θ value	1.98959e-140 (rank : 3)	NC score	0.856944 (rank : 3)
Query Neighborhood Hits	109	Target Neighborhood Hits	248	Shared Neighborhood Hits	25
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

IRS2_HUMAN
θ value	7.07634e-138 (rank : 4)	NC score	0.850260 (rank : 4)
Query Neighborhood Hits	109	Target Neighborhood Hits	262	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

GAB2_MOUSE
θ value	7.59969e-07 (rank : 5)	NC score	0.253146 (rank : 10)
Query Neighborhood Hits	109	Target Neighborhood Hits	220	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

DOK6_HUMAN
θ value	1.69304e-06 (rank : 6)	NC score	0.288255 (rank : 5)
Query Neighborhood Hits	109	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PKX4, Q4V9S3, Q8WUZ8, Q96HI2, Q96LU2	Gene names	DOK6, DOK5L
Domain Architecture	No domain graphic available
Description	Docking protein 6 (Downstream of tyrosine kinase 6).

GAB2_HUMAN
θ value	2.88788e-06 (rank : 7)	NC score	0.246857 (rank : 12)
Query Neighborhood Hits	109	Target Neighborhood Hits	188	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

DOK5_MOUSE
θ value	4.92598e-06 (rank : 8)	NC score	0.284636 (rank : 6)
Query Neighborhood Hits	109	Target Neighborhood Hits	27	Shared Neighborhood Hits	11
SwissProt Accessions	Q91ZM9, Q8BRI3, Q9CSM6	Gene names	Dok5
Domain Architecture
Description	Docking protein 5 (Downstream of tyrosine kinase 5) (Protein dok-5).

DOK4_HUMAN
θ value	6.43352e-06 (rank : 9)	NC score	0.256927 (rank : 9)
Query Neighborhood Hits	109	Target Neighborhood Hits	28	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TEW6, O75209, Q9BTP2, Q9NVV3	Gene names	DOK4
Domain Architecture	No domain graphic available
Description	Docking protein 4 (Downstream of tyrosine kinase 4).

DOK4_MOUSE
θ value	1.43324e-05 (rank : 10)	NC score	0.252940 (rank : 11)
Query Neighborhood Hits	109	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q99KE3, Q3U0X3	Gene names	Dok4
Domain Architecture	No domain graphic available
Description	Docking protein 4 (Downstream of tyrosine kinase 4).

DOK5_HUMAN
θ value	2.44474e-05 (rank : 11)	NC score	0.276701 (rank : 7)
Query Neighborhood Hits	109	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P104, Q5T7Y0, Q5TE53, Q8TEW7, Q96H13, Q9BZ24, Q9NQF4, Q9Y411	Gene names	DOK5, C20orf180
Domain Architecture
Description	Docking protein 5 (Downstream of tyrosine kinase 5) (IRS6) (Protein dok-5).

GAB1_HUMAN
θ value	4.1701e-05 (rank : 12)	NC score	0.269459 (rank : 8)
Query Neighborhood Hits	109	Target Neighborhood Hits	279	Shared Neighborhood Hits	28
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAB1_MOUSE
θ value	9.29e-05 (rank : 13)	NC score	0.215390 (rank : 13)
Query Neighborhood Hits	109	Target Neighborhood Hits	233	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

DOCK9_MOUSE
θ value	0.00298849 (rank : 14)	NC score	0.095109 (rank : 15)
Query Neighborhood Hits	109	Target Neighborhood Hits	79	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BIK4, Q921Y6	Gene names	Dock9, D14Wsu89e, Kiaa1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

DOCK9_HUMAN
θ value	0.00390308 (rank : 15)	NC score	0.092135 (rank : 16)
Query Neighborhood Hits	109	Target Neighborhood Hits	82	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BZ29, Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26, Q9BZ27, Q9BZ28, Q9UPU4	Gene names	DOCK9, KIAA1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

TFE2_HUMAN
θ value	0.00665767 (rank : 16)	NC score	0.060335 (rank : 24)
Query Neighborhood Hits	109	Target Neighborhood Hits	161	Shared Neighborhood Hits	9
SwissProt Accessions	P15923, P15883, Q14208, Q14635, Q14636, Q9UPI9	Gene names	TCF3, E2A, ITF1
Domain Architecture
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Immunoglobulin transcription factor 1) (Transcription factor ITF-1) (Kappa-E2-binding factor).

RNPS1_HUMAN
θ value	0.0431538 (rank : 17)	NC score	0.085838 (rank : 17)
Query Neighborhood Hits	109	Target Neighborhood Hits	285	Shared Neighborhood Hits	9
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
θ value	0.0431538 (rank : 18)	NC score	0.085838 (rank : 18)
Query Neighborhood Hits	109	Target Neighborhood Hits	285	Shared Neighborhood Hits	9
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

ULK2_HUMAN
θ value	0.0431538 (rank : 19)	NC score	0.013893 (rank : 81)
Query Neighborhood Hits	109	Target Neighborhood Hits	979	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

AL2S8_MOUSE
θ value	0.163984 (rank : 20)	NC score	0.047813 (rank : 35)
Query Neighborhood Hits	109	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHI4	Gene names	Als2cr8, Carf
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein homolog (Calcium-response factor) (CaRF).

ANR11_HUMAN
θ value	0.21417 (rank : 21)	NC score	0.024994 (rank : 61)
Query Neighborhood Hits	109	Target Neighborhood Hits	1289	Shared Neighborhood Hits	25
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CSKI2_MOUSE
θ value	0.279714 (rank : 22)	NC score	0.023096 (rank : 62)
Query Neighborhood Hits	109	Target Neighborhood Hits	812	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

KLF17_MOUSE
θ value	0.279714 (rank : 23)	NC score	0.005346 (rank : 108)
Query Neighborhood Hits	109	Target Neighborhood Hits	684	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CFA7, Q3UT30, Q6P233, Q9D351	Gene names	Klf17, Gzf, Zfp393, Znf393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393) (Germ cell-specific zinc finger protein).

ABCA1_MOUSE
θ value	0.47712 (rank : 24)	NC score	0.018081 (rank : 74)
Query Neighborhood Hits	109	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	P41233	Gene names	Abca1, Abc1
Domain Architecture
Description	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ATP-binding cassette 1) (ABC-1).

GON4L_HUMAN
θ value	0.47712 (rank : 25)	NC score	0.049823 (rank : 32)
Query Neighborhood Hits	109	Target Neighborhood Hits	555	Shared Neighborhood Hits	17
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

FHOD1_MOUSE
θ value	0.62314 (rank : 26)	NC score	0.039472 (rank : 45)
Query Neighborhood Hits	109	Target Neighborhood Hits	217	Shared Neighborhood Hits	12
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

GLI1_HUMAN
θ value	0.62314 (rank : 27)	NC score	0.008434 (rank : 96)
Query Neighborhood Hits	109	Target Neighborhood Hits	828	Shared Neighborhood Hits	13
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

MAGE1_HUMAN
θ value	0.62314 (rank : 28)	NC score	0.041071 (rank : 44)
Query Neighborhood Hits	109	Target Neighborhood Hits	1389	Shared Neighborhood Hits	40
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MTR1L_MOUSE
θ value	0.62314 (rank : 29)	NC score	0.004162 (rank : 112)
Query Neighborhood Hits	109	Target Neighborhood Hits	903	Shared Neighborhood Hits	2
SwissProt Accessions	O88495	Gene names	Gpr50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

SOS2_HUMAN
θ value	0.62314 (rank : 30)	NC score	0.034154 (rank : 52)
Query Neighborhood Hits	109	Target Neighborhood Hits	193	Shared Neighborhood Hits	13
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

UTX_HUMAN
θ value	0.62314 (rank : 31)	NC score	0.028448 (rank : 56)
Query Neighborhood Hits	109	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	O15550	Gene names	UTX
Domain Architecture
Description	Ubiquitously transcribed X chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the X chromosome).

CIC_HUMAN
θ value	0.813845 (rank : 32)	NC score	0.043958 (rank : 41)
Query Neighborhood Hits	109	Target Neighborhood Hits	992	Shared Neighborhood Hits	35
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

ZN645_HUMAN
θ value	0.813845 (rank : 33)	NC score	0.052789 (rank : 29)
Query Neighborhood Hits	109	Target Neighborhood Hits	265	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

ABCA1_HUMAN
θ value	1.06291 (rank : 34)	NC score	0.017070 (rank : 76)
Query Neighborhood Hits	109	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	O95477, Q96S56, Q96T85, Q9NQV4, Q9UN06, Q9UN07, Q9UN08, Q9UN09	Gene names	ABCA1, ABC1, CERP
Domain Architecture
Description	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ATP-binding cassette 1) (ABC-1) (Cholesterol efflux regulatory protein).

SYNP2_HUMAN
θ value	1.06291 (rank : 35)	NC score	0.036013 (rank : 49)
Query Neighborhood Hits	109	Target Neighborhood Hits	323	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

T22D2_HUMAN
θ value	1.06291 (rank : 36)	NC score	0.046305 (rank : 39)
Query Neighborhood Hits	109	Target Neighborhood Hits	250	Shared Neighborhood Hits	17
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

YTDC2_HUMAN
θ value	1.06291 (rank : 37)	NC score	0.020519 (rank : 67)
Query Neighborhood Hits	109	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H6S0	Gene names	YTHDC2
Domain Architecture	No domain graphic available
Description	YTH domain-containing protein 2.

ATX2_MOUSE
θ value	1.38821 (rank : 38)	NC score	0.035207 (rank : 50)
Query Neighborhood Hits	109	Target Neighborhood Hits	445	Shared Neighborhood Hits	17
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

K0310_HUMAN
θ value	1.38821 (rank : 39)	NC score	0.059049 (rank : 26)
Query Neighborhood Hits	109	Target Neighborhood Hits	420	Shared Neighborhood Hits	25
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

MAP1A_HUMAN
θ value	1.38821 (rank : 40)	NC score	0.033188 (rank : 53)
Query Neighborhood Hits	109	Target Neighborhood Hits	1626	Shared Neighborhood Hits	33
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

NFAC3_HUMAN
θ value	1.38821 (rank : 41)	NC score	0.025734 (rank : 60)
Query Neighborhood Hits	109	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	Q12968, O75211, Q14516, Q99840, Q99841, Q99842	Gene names	NFATC3, NFAT4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

OTU7A_MOUSE
θ value	1.38821 (rank : 42)	NC score	0.022345 (rank : 64)
Query Neighborhood Hits	109	Target Neighborhood Hits	91	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R554	Gene names	Otud7a, Otud7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

ARBK1_MOUSE
θ value	1.81305 (rank : 43)	NC score	0.008370 (rank : 97)
Query Neighborhood Hits	109	Target Neighborhood Hits	849	Shared Neighborhood Hits	11
SwissProt Accessions	Q99MK8, Q99LL8	Gene names	Adrbk1, Grk2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein-coupled receptor kinase 2).

SMAL1_HUMAN
θ value	1.81305 (rank : 44)	NC score	0.019016 (rank : 71)
Query Neighborhood Hits	109	Target Neighborhood Hits	174	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

SPEG_MOUSE
θ value	1.81305 (rank : 45)	NC score	0.012809 (rank : 85)
Query Neighborhood Hits	109	Target Neighborhood Hits	1959	Shared Neighborhood Hits	39
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ARBK1_HUMAN
θ value	2.36792 (rank : 46)	NC score	0.007886 (rank : 98)
Query Neighborhood Hits	109	Target Neighborhood Hits	859	Shared Neighborhood Hits	11
SwissProt Accessions	P25098, Q13837	Gene names	ADRBK1, BARK, BARK1, GRK2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein coupled receptor kinase 2).

GP124_MOUSE
θ value	2.36792 (rank : 47)	NC score	0.012621 (rank : 86)
Query Neighborhood Hits	109	Target Neighborhood Hits	423	Shared Neighborhood Hits	9
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

ITF2_HUMAN
θ value	2.36792 (rank : 48)	NC score	0.048921 (rank : 33)
Query Neighborhood Hits	109	Target Neighborhood Hits	168	Shared Neighborhood Hits	11
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

MYO10_HUMAN
θ value	2.36792 (rank : 49)	NC score	0.019459 (rank : 70)
Query Neighborhood Hits	109	Target Neighborhood Hits	920	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

RUNX3_MOUSE
θ value	2.36792 (rank : 50)	NC score	0.034774 (rank : 51)
Query Neighborhood Hits	109	Target Neighborhood Hits	113	Shared Neighborhood Hits	9
SwissProt Accessions	Q64131, Q99P92, Q9R199	Gene names	Runx3, Aml2, Cbfa3, Pebp2a3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

SRRM2_HUMAN
θ value	2.36792 (rank : 51)	NC score	0.063913 (rank : 22)
Query Neighborhood Hits	109	Target Neighborhood Hits	1296	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SYCP1_HUMAN
θ value	2.36792 (rank : 52)	NC score	0.009993 (rank : 94)
Query Neighborhood Hits	109	Target Neighborhood Hits	1313	Shared Neighborhood Hits	16
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

APOA_HUMAN
θ value	3.0926 (rank : 53)	NC score	0.004214 (rank : 111)
Query Neighborhood Hits	109	Target Neighborhood Hits	221	Shared Neighborhood Hits	2
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

ATN1_HUMAN
θ value	3.0926 (rank : 54)	NC score	0.026343 (rank : 59)
Query Neighborhood Hits	109	Target Neighborhood Hits	676	Shared Neighborhood Hits	27
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

GPTC8_HUMAN
θ value	3.0926 (rank : 55)	NC score	0.037502 (rank : 46)
Query Neighborhood Hits	109	Target Neighborhood Hits	366	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

ITF2_MOUSE
θ value	3.0926 (rank : 56)	NC score	0.047084 (rank : 36)
Query Neighborhood Hits	109	Target Neighborhood Hits	154	Shared Neighborhood Hits	10
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).

MUS81_HUMAN
θ value	3.0926 (rank : 57)	NC score	0.021827 (rank : 65)
Query Neighborhood Hits	109	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q96NY9, Q9H7D9	Gene names	MUS81
Domain Architecture
Description	Crossover junction endonuclease MUS81 (EC 3.1.22.-).

PLEK2_HUMAN
θ value	3.0926 (rank : 58)	NC score	0.043294 (rank : 42)
Query Neighborhood Hits	109	Target Neighborhood Hits	101	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

SRRM2_MOUSE
θ value	3.0926 (rank : 59)	NC score	0.061797 (rank : 23)
Query Neighborhood Hits	109	Target Neighborhood Hits	1470	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

AGRIN_HUMAN
θ value	4.03905 (rank : 60)	NC score	0.005491 (rank : 107)
Query Neighborhood Hits	109	Target Neighborhood Hits	582	Shared Neighborhood Hits	6
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

CB013_HUMAN
θ value	4.03905 (rank : 61)	NC score	0.036959 (rank : 47)
Query Neighborhood Hits	109	Target Neighborhood Hits	55	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IW19, Q53P47, Q53PB9, Q53QU0	Gene names	C2orf13
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf13.

DOK3_MOUSE
θ value	4.03905 (rank : 62)	NC score	0.059223 (rank : 25)
Query Neighborhood Hits	109	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QZK7	Gene names	Dok3, Dokl
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3) (P62(dok)-like protein) (DOK-L).

GRIN1_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.028015 (rank : 58)
Query Neighborhood Hits	109	Target Neighborhood Hits	681	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

HXD8_MOUSE
θ value	4.03905 (rank : 64)	NC score	0.006559 (rank : 103)
Query Neighborhood Hits	109	Target Neighborhood Hits	333	Shared Neighborhood Hits	3
SwissProt Accessions	P23463	Gene names	Hoxd8, Hox-4.3, Hoxd-8
Domain Architecture
Description	Homeobox protein Hox-D8 (Hox-4.3) (Hox-5.4).

K0323_HUMAN
θ value	4.03905 (rank : 65)	NC score	0.051270 (rank : 31)
Query Neighborhood Hits	109	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	O15037, Q86TZ6, Q8IUQ2, Q96BA9	Gene names	KIAA0323
Domain Architecture	No domain graphic available
Description	Protein KIAA0323.

MAP1B_HUMAN
θ value	4.03905 (rank : 66)	NC score	0.046301 (rank : 40)
Query Neighborhood Hits	109	Target Neighborhood Hits	903	Shared Neighborhood Hits	22
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MAP1B_MOUSE
θ value	4.03905 (rank : 67)	NC score	0.030735 (rank : 54)
Query Neighborhood Hits	109	Target Neighborhood Hits	977	Shared Neighborhood Hits	19
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

NGN2_MOUSE
θ value	4.03905 (rank : 68)	NC score	0.010517 (rank : 93)
Query Neighborhood Hits	109	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	P70447, P70237	Gene names	Neurog2, Ath4a, Atoh4, Ngn2
Domain Architecture
Description	Neurogenin 2 (Atonal protein homolog 4) (Helix-loop-helix protein mATH-4A) (MATH4A).

NNP1_MOUSE
θ value	4.03905 (rank : 69)	NC score	0.018302 (rank : 72)
Query Neighborhood Hits	109	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	P56183, O35712, Q9ERE1, Q9JI07, Q9JK67, Q9JKU2	Gene names	Nnp1
Domain Architecture
Description	NNP-1 protein (Novel nuclear protein 1) (Nop52).

PKHA1_MOUSE
θ value	4.03905 (rank : 70)	NC score	0.055292 (rank : 27)
Query Neighborhood Hits	109	Target Neighborhood Hits	120	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PLEK2_MOUSE
θ value	4.03905 (rank : 71)	NC score	0.041508 (rank : 43)
Query Neighborhood Hits	109	Target Neighborhood Hits	96	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

TB182_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.021361 (rank : 66)
Query Neighborhood Hits	109	Target Neighborhood Hits	414	Shared Neighborhood Hits	16
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

APC_HUMAN
θ value	5.27518 (rank : 73)	NC score	0.022840 (rank : 63)
Query Neighborhood Hits	109	Target Neighborhood Hits	603	Shared Neighborhood Hits	19
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

IBP2_HUMAN
θ value	5.27518 (rank : 74)	NC score	0.010819 (rank : 92)
Query Neighborhood Hits	109	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	P18065, Q14619, Q9UCL3	Gene names	IGFBP2, BP2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

INHBE_MOUSE
θ value	5.27518 (rank : 75)	NC score	0.006868 (rank : 101)
Query Neighborhood Hits	109	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	O08717	Gene names	Inhbe
Domain Architecture
Description	Inhibin beta E chain precursor (Activin beta-E chain).

PKHA6_MOUSE
θ value	5.27518 (rank : 76)	NC score	0.046887 (rank : 37)
Query Neighborhood Hits	109	Target Neighborhood Hits	591	Shared Neighborhood Hits	30
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

SSPO_MOUSE
θ value	5.27518 (rank : 77)	NC score	0.003685 (rank : 113)
Query Neighborhood Hits	109	Target Neighborhood Hits	800	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

TDRD3_MOUSE
θ value	5.27518 (rank : 78)	NC score	0.015400 (rank : 78)
Query Neighborhood Hits	109	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q91W18, Q8BZW6	Gene names	Tdrd3
Domain Architecture
Description	Tudor domain-containing protein 3.

TRIO_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.005152 (rank : 109)
Query Neighborhood Hits	109	Target Neighborhood Hits	1580	Shared Neighborhood Hits	21
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

TTBK1_HUMAN
θ value	5.27518 (rank : 80)	NC score	0.006075 (rank : 104)
Query Neighborhood Hits	109	Target Neighborhood Hits	1058	Shared Neighborhood Hits	21
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

CM007_MOUSE
θ value	6.88961 (rank : 81)	NC score	0.017714 (rank : 75)
Query Neighborhood Hits	109	Target Neighborhood Hits	416	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

CSKI2_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.013483 (rank : 82)
Query Neighborhood Hits	109	Target Neighborhood Hits	747	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

DSCAM_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.003010 (rank : 114)
Query Neighborhood Hits	109	Target Neighborhood Hits	524	Shared Neighborhood Hits	7
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

FRS2_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.051703 (rank : 30)
Query Neighborhood Hits	109	Target Neighborhood Hits	40	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WU20, O43558, Q7LDQ6	Gene names	FRS2
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (Suc1-associated neurotrophic factor target 1) (SNT-1) (FGFR signaling adaptor SNT).

GTR8_MOUSE
θ value	6.88961 (rank : 85)	NC score	0.007123 (rank : 100)
Query Neighborhood Hits	109	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JIF3, Q9JJP4, Q9JJZ0	Gene names	Slc2a8, Glut8, GlutX1
Domain Architecture
Description	Solute carrier family 2, facilitated glucose transporter member 8 (Glucose transporter type 8) (Glucose transporter type X1).

NOVA1_HUMAN
θ value	6.88961 (rank : 86)	NC score	0.011010 (rank : 91)
Query Neighborhood Hits	109	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	P51513	Gene names	NOVA1
Domain Architecture
Description	RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Onconeural ventral antigen 1) (Paraneoplastic Ri antigen) (Ventral neuron-specific protein 1).

OAZ1_MOUSE
θ value	6.88961 (rank : 87)	NC score	0.019539 (rank : 69)
Query Neighborhood Hits	109	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P54369, O08610	Gene names	Oaz1, Oaz
Domain Architecture
Description	Ornithine decarboxylase antizyme (ODC-Az).

PHLB1_HUMAN
θ value	6.88961 (rank : 88)	NC score	0.030677 (rank : 55)
Query Neighborhood Hits	109	Target Neighborhood Hits	1038	Shared Neighborhood Hits	37
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PKHA6_HUMAN
θ value	6.88961 (rank : 89)	NC score	0.036717 (rank : 48)
Query Neighborhood Hits	109	Target Neighborhood Hits	556	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

RP1L1_MOUSE
θ value	6.88961 (rank : 90)	NC score	0.012212 (rank : 87)
Query Neighborhood Hits	109	Target Neighborhood Hits	170	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

SPRE3_MOUSE
θ value	6.88961 (rank : 91)	NC score	0.018127 (rank : 73)
Query Neighborhood Hits	109	Target Neighborhood Hits	111	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P6N5, Q7TNJ8	Gene names	Spred3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

TCF19_MOUSE
θ value	6.88961 (rank : 92)	NC score	0.048497 (rank : 34)
Query Neighborhood Hits	109	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q99KJ5, Q8BPA3, Q9CT93	Gene names	Tcf19, Sc1
Domain Architecture
Description	Transcription factor 19-like protein (SC1 protein homolog).

TMF1_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.004321 (rank : 110)
Query Neighborhood Hits	109	Target Neighborhood Hits	987	Shared Neighborhood Hits	12
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

ULK2_MOUSE
θ value	6.88961 (rank : 94)	NC score	0.007450 (rank : 99)
Query Neighborhood Hits	109	Target Neighborhood Hits	943	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QY01, Q80TV7, Q9WTP4	Gene names	Ulk2, Kiaa0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2).

BAZ2A_MOUSE
θ value	8.99809 (rank : 95)	NC score	0.009473 (rank : 95)
Query Neighborhood Hits	109	Target Neighborhood Hits	744	Shared Neighborhood Hits	25
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CBL_HUMAN
θ value	8.99809 (rank : 96)	NC score	0.012053 (rank : 88)
Query Neighborhood Hits	109	Target Neighborhood Hits	353	Shared Neighborhood Hits	11
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CRTC1_HUMAN
θ value	8.99809 (rank : 97)	NC score	0.016243 (rank : 77)
Query Neighborhood Hits	109	Target Neighborhood Hits	319	Shared Neighborhood Hits	13
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

FBX10_HUMAN
θ value	8.99809 (rank : 98)	NC score	0.020080 (rank : 68)
Query Neighborhood Hits	109	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UK96, Q5JRT8, Q9UKC3	Gene names	FBXO10, FBX10
Domain Architecture	No domain graphic available
Description	F-box only protein 10.

LRRF2_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.011248 (rank : 90)
Query Neighborhood Hits	109	Target Neighborhood Hits	791	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

LRRF2_MOUSE
θ value	8.99809 (rank : 100)	NC score	0.014654 (rank : 80)
Query Neighborhood Hits	109	Target Neighborhood Hits	556	Shared Neighborhood Hits	8
SwissProt Accessions	Q91WK0, Q8BVD1, Q9CU89	Gene names	Lrrfip2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

PAR3L_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.005977 (rank : 106)
Query Neighborhood Hits	109	Target Neighborhood Hits	297	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

PCLO_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.013335 (rank : 83)
Query Neighborhood Hits	109	Target Neighborhood Hits	2046	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PDZD2_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.028207 (rank : 57)
Query Neighborhood Hits	109	Target Neighborhood Hits	772	Shared Neighborhood Hits	25
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PKHA1_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.046708 (rank : 38)
Query Neighborhood Hits	109	Target Neighborhood Hits	127	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

RAI1_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.015064 (rank : 79)
Query Neighborhood Hits	109	Target Neighborhood Hits	360	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

SEM6C_MOUSE
θ value	8.99809 (rank : 106)	NC score	0.011841 (rank : 89)
Query Neighborhood Hits	109	Target Neighborhood Hits	352	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SMAL1_MOUSE
θ value	8.99809 (rank : 107)	NC score	0.013210 (rank : 84)
Query Neighborhood Hits	109	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

T2R41_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.006072 (rank : 105)
Query Neighborhood Hits	109	Target Neighborhood Hits	77	Shared Neighborhood Hits	3
SwissProt Accessions	P59536, P59550	Gene names	TAS2R41
Domain Architecture
Description	Taste receptor type 2 member 41 (T2R41) (T2R59).

TGIF_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.006765 (rank : 102)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	Q15583, Q6ICR0, Q8N5X9, Q9NRS0	Gene names	TGIF
Domain Architecture
Description	5'-TG-3'-interacting factor (Homeobox protein TGIF).

DOC10_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.066127 (rank : 20)
Query Neighborhood Hits	109	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).

DOK1_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.063976 (rank : 21)
Query Neighborhood Hits	109	Target Neighborhood Hits	85	Shared Neighborhood Hits	12
SwissProt Accessions	Q99704, O43204, Q9UHG6	Gene names	DOK1
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62).

DOK1_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.053553 (rank : 28)
Query Neighborhood Hits	109	Target Neighborhood Hits	82	Shared Neighborhood Hits	8
SwissProt Accessions	P97465, Q9R213	Gene names	Dok1, Dok
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)).

DOK2_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.076541 (rank : 19)
Query Neighborhood Hits	109	Target Neighborhood Hits	46	Shared Neighborhood Hits	11
SwissProt Accessions	O60496	Gene names	DOK2
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)).

DOK2_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.101241 (rank : 14)
Query Neighborhood Hits	109	Target Neighborhood Hits	244	Shared Neighborhood Hits	19
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

Hits sorted by NC score

IRS1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	109
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

IRS1_MOUSE
NC score	0.981650 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	109	Target Neighborhood Hits	112	Shared Neighborhood Hits	62
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

IRS2_MOUSE
NC score	0.856944 (rank : 3)	θ value	1.98959e-140 (rank : 3)
Query Neighborhood Hits	109	Target Neighborhood Hits	248	Shared Neighborhood Hits	25
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

IRS2_HUMAN
NC score	0.850260 (rank : 4)	θ value	7.07634e-138 (rank : 4)
Query Neighborhood Hits	109	Target Neighborhood Hits	262	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

DOK6_HUMAN
NC score	0.288255 (rank : 5)	θ value	1.69304e-06 (rank : 6)
Query Neighborhood Hits	109	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PKX4, Q4V9S3, Q8WUZ8, Q96HI2, Q96LU2	Gene names	DOK6, DOK5L
Domain Architecture	No domain graphic available
Description	Docking protein 6 (Downstream of tyrosine kinase 6).

DOK5_MOUSE
NC score	0.284636 (rank : 6)	θ value	4.92598e-06 (rank : 8)
Query Neighborhood Hits	109	Target Neighborhood Hits	27	Shared Neighborhood Hits	11
SwissProt Accessions	Q91ZM9, Q8BRI3, Q9CSM6	Gene names	Dok5
Domain Architecture
Description	Docking protein 5 (Downstream of tyrosine kinase 5) (Protein dok-5).

DOK5_HUMAN
NC score	0.276701 (rank : 7)	θ value	2.44474e-05 (rank : 11)
Query Neighborhood Hits	109	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P104, Q5T7Y0, Q5TE53, Q8TEW7, Q96H13, Q9BZ24, Q9NQF4, Q9Y411	Gene names	DOK5, C20orf180
Domain Architecture
Description	Docking protein 5 (Downstream of tyrosine kinase 5) (IRS6) (Protein dok-5).

GAB1_HUMAN
NC score	0.269459 (rank : 8)	θ value	4.1701e-05 (rank : 12)
Query Neighborhood Hits	109	Target Neighborhood Hits	279	Shared Neighborhood Hits	28
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

DOK4_HUMAN
NC score	0.256927 (rank : 9)	θ value	6.43352e-06 (rank : 9)
Query Neighborhood Hits	109	Target Neighborhood Hits	28	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TEW6, O75209, Q9BTP2, Q9NVV3	Gene names	DOK4
Domain Architecture	No domain graphic available
Description	Docking protein 4 (Downstream of tyrosine kinase 4).

GAB2_MOUSE
NC score	0.253146 (rank : 10)	θ value	7.59969e-07 (rank : 5)
Query Neighborhood Hits	109	Target Neighborhood Hits	220	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

DOK4_MOUSE
NC score	0.252940 (rank : 11)	θ value	1.43324e-05 (rank : 10)
Query Neighborhood Hits	109	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q99KE3, Q3U0X3	Gene names	Dok4
Domain Architecture	No domain graphic available
Description	Docking protein 4 (Downstream of tyrosine kinase 4).

GAB2_HUMAN
NC score	0.246857 (rank : 12)	θ value	2.88788e-06 (rank : 7)
Query Neighborhood Hits	109	Target Neighborhood Hits	188	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

GAB1_MOUSE
NC score	0.215390 (rank : 13)	θ value	9.29e-05 (rank : 13)
Query Neighborhood Hits	109	Target Neighborhood Hits	233	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

DOK2_MOUSE
NC score	0.101241 (rank : 14)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	109	Target Neighborhood Hits	244	Shared Neighborhood Hits	19
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

DOCK9_MOUSE
NC score	0.095109 (rank : 15)	θ value	0.00298849 (rank : 14)
Query Neighborhood Hits	109	Target Neighborhood Hits	79	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BIK4, Q921Y6	Gene names	Dock9, D14Wsu89e, Kiaa1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

DOCK9_HUMAN
NC score	0.092135 (rank : 16)	θ value	0.00390308 (rank : 15)
Query Neighborhood Hits	109	Target Neighborhood Hits	82	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BZ29, Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26, Q9BZ27, Q9BZ28, Q9UPU4	Gene names	DOCK9, KIAA1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

RNPS1_HUMAN
NC score	0.085838 (rank : 17)	θ value	0.0431538 (rank : 17)
Query Neighborhood Hits	109	Target Neighborhood Hits	285	Shared Neighborhood Hits	9
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
NC score	0.085838 (rank : 18)	θ value	0.0431538 (rank : 18)
Query Neighborhood Hits	109	Target Neighborhood Hits	285	Shared Neighborhood Hits	9
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

DOK2_HUMAN
NC score	0.076541 (rank : 19)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	109	Target Neighborhood Hits	46	Shared Neighborhood Hits	11
SwissProt Accessions	O60496	Gene names	DOK2
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)).

DOC10_HUMAN
NC score	0.066127 (rank : 20)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	109	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).

DOK1_HUMAN
NC score	0.063976 (rank : 21)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	109	Target Neighborhood Hits	85	Shared Neighborhood Hits	12
SwissProt Accessions	Q99704, O43204, Q9UHG6	Gene names	DOK1
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62).

SRRM2_HUMAN
NC score	0.063913 (rank : 22)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	109	Target Neighborhood Hits	1296	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
NC score	0.061797 (rank : 23)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	109	Target Neighborhood Hits	1470	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TFE2_HUMAN
NC score	0.060335 (rank : 24)	θ value	0.00665767 (rank : 16)
Query Neighborhood Hits	109	Target Neighborhood Hits	161	Shared Neighborhood Hits	9
SwissProt Accessions	P15923, P15883, Q14208, Q14635, Q14636, Q9UPI9	Gene names	TCF3, E2A, ITF1
Domain Architecture
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Immunoglobulin transcription factor 1) (Transcription factor ITF-1) (Kappa-E2-binding factor).

DOK3_MOUSE
NC score	0.059223 (rank : 25)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	109	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QZK7	Gene names	Dok3, Dokl
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3) (P62(dok)-like protein) (DOK-L).

K0310_HUMAN
NC score	0.059049 (rank : 26)	θ value	1.38821 (rank : 39)
Query Neighborhood Hits	109	Target Neighborhood Hits	420	Shared Neighborhood Hits	25
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

PKHA1_MOUSE
NC score	0.055292 (rank : 27)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	109	Target Neighborhood Hits	120	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

DOK1_MOUSE
NC score	0.053553 (rank : 28)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	109	Target Neighborhood Hits	82	Shared Neighborhood Hits	8
SwissProt Accessions	P97465, Q9R213	Gene names	Dok1, Dok
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)).

ZN645_HUMAN
NC score	0.052789 (rank : 29)	θ value	0.813845 (rank : 33)
Query Neighborhood Hits	109	Target Neighborhood Hits	265	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

FRS2_HUMAN
NC score	0.051703 (rank : 30)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	109	Target Neighborhood Hits	40	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WU20, O43558, Q7LDQ6	Gene names	FRS2
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (Suc1-associated neurotrophic factor target 1) (SNT-1) (FGFR signaling adaptor SNT).

K0323_HUMAN
NC score	0.051270 (rank : 31)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	109	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	O15037, Q86TZ6, Q8IUQ2, Q96BA9	Gene names	KIAA0323
Domain Architecture	No domain graphic available
Description	Protein KIAA0323.

GON4L_HUMAN
NC score	0.049823 (rank : 32)	θ value	0.47712 (rank : 25)
Query Neighborhood Hits	109	Target Neighborhood Hits	555	Shared Neighborhood Hits	17
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

ITF2_HUMAN
NC score	0.048921 (rank : 33)	θ value	2.36792 (rank : 48)
Query Neighborhood Hits	109	Target Neighborhood Hits	168	Shared Neighborhood Hits	11
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

TCF19_MOUSE
NC score	0.048497 (rank : 34)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	109	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q99KJ5, Q8BPA3, Q9CT93	Gene names	Tcf19, Sc1
Domain Architecture
Description	Transcription factor 19-like protein (SC1 protein homolog).

AL2S8_MOUSE
NC score	0.047813 (rank : 35)	θ value	0.163984 (rank : 20)
Query Neighborhood Hits	109	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHI4	Gene names	Als2cr8, Carf
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein homolog (Calcium-response factor) (CaRF).

ITF2_MOUSE
NC score	0.047084 (rank : 36)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	109	Target Neighborhood Hits	154	Shared Neighborhood Hits	10
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).

PKHA6_MOUSE
NC score	0.046887 (rank : 37)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	109	Target Neighborhood Hits	591	Shared Neighborhood Hits	30
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA1_HUMAN
NC score	0.046708 (rank : 38)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	109	Target Neighborhood Hits	127	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

T22D2_HUMAN
NC score	0.046305 (rank : 39)	θ value	1.06291 (rank : 36)
Query Neighborhood Hits	109	Target Neighborhood Hits	250	Shared Neighborhood Hits	17
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

MAP1B_HUMAN
NC score	0.046301 (rank : 40)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	109	Target Neighborhood Hits	903	Shared Neighborhood Hits	22
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

CIC_HUMAN
NC score	0.043958 (rank : 41)	θ value	0.813845 (rank : 32)
Query Neighborhood Hits	109	Target Neighborhood Hits	992	Shared Neighborhood Hits	35
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

PLEK2_HUMAN
NC score	0.043294 (rank : 42)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	109	Target Neighborhood Hits	101	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_MOUSE
NC score	0.041508 (rank : 43)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	109	Target Neighborhood Hits	96	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

MAGE1_HUMAN
NC score	0.041071 (rank : 44)	θ value	0.62314 (rank : 28)
Query Neighborhood Hits	109	Target Neighborhood Hits	1389	Shared Neighborhood Hits	40
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

FHOD1_MOUSE
NC score	0.039472 (rank : 45)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	109	Target Neighborhood Hits	217	Shared Neighborhood Hits	12
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

GPTC8_HUMAN
NC score	0.037502 (rank : 46)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	109	Target Neighborhood Hits	366	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

CB013_HUMAN
NC score	0.036959 (rank : 47)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	109	Target Neighborhood Hits	55	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IW19, Q53P47, Q53PB9, Q53QU0	Gene names	C2orf13
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf13.

PKHA6_HUMAN
NC score	0.036717 (rank : 48)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	109	Target Neighborhood Hits	556	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

SYNP2_HUMAN
NC score	0.036013 (rank : 49)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	109	Target Neighborhood Hits	323	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

ATX2_MOUSE
NC score	0.035207 (rank : 50)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	109	Target Neighborhood Hits	445	Shared Neighborhood Hits	17
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

RUNX3_MOUSE
NC score	0.034774 (rank : 51)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	109	Target Neighborhood Hits	113	Shared Neighborhood Hits	9
SwissProt Accessions	Q64131, Q99P92, Q9R199	Gene names	Runx3, Aml2, Cbfa3, Pebp2a3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

SOS2_HUMAN
NC score	0.034154 (rank : 52)	θ value	0.62314 (rank : 30)
Query Neighborhood Hits	109	Target Neighborhood Hits	193	Shared Neighborhood Hits	13
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

MAP1A_HUMAN
NC score	0.033188 (rank : 53)	θ value	1.38821 (rank : 40)
Query Neighborhood Hits	109	Target Neighborhood Hits	1626	Shared Neighborhood Hits	33
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MAP1B_MOUSE
NC score	0.030735 (rank : 54)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	109	Target Neighborhood Hits	977	Shared Neighborhood Hits	19
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

PHLB1_HUMAN
NC score	0.030677 (rank : 55)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	109	Target Neighborhood Hits	1038	Shared Neighborhood Hits	37
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

UTX_HUMAN
NC score	0.028448 (rank : 56)	θ value	0.62314 (rank : 31)
Query Neighborhood Hits	109	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	O15550	Gene names	UTX
Domain Architecture
Description	Ubiquitously transcribed X chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the X chromosome).

PDZD2_HUMAN
NC score	0.028207 (rank : 57)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	109	Target Neighborhood Hits	772	Shared Neighborhood Hits	25
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

GRIN1_HUMAN
NC score	0.028015 (rank : 58)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	109	Target Neighborhood Hits	681	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

ATN1_HUMAN
NC score	0.026343 (rank : 59)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	109	Target Neighborhood Hits	676	Shared Neighborhood Hits	27
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

NFAC3_HUMAN
NC score	0.025734 (rank : 60)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	109	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	Q12968, O75211, Q14516, Q99840, Q99841, Q99842	Gene names	NFATC3, NFAT4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

ANR11_HUMAN
NC score	0.024994 (rank : 61)	θ value	0.21417 (rank : 21)
Query Neighborhood Hits	109	Target Neighborhood Hits	1289	Shared Neighborhood Hits	25
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CSKI2_MOUSE
NC score	0.023096 (rank : 62)	θ value	0.279714 (rank : 22)
Query Neighborhood Hits	109	Target Neighborhood Hits	812	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

APC_HUMAN
NC score	0.022840 (rank : 63)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	109	Target Neighborhood Hits	603	Shared Neighborhood Hits	19
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

OTU7A_MOUSE
NC score	0.022345 (rank : 64)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	109	Target Neighborhood Hits	91	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R554	Gene names	Otud7a, Otud7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

MUS81_HUMAN
NC score	0.021827 (rank : 65)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	109	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q96NY9, Q9H7D9	Gene names	MUS81
Domain Architecture
Description	Crossover junction endonuclease MUS81 (EC 3.1.22.-).

TB182_HUMAN
NC score	0.021361 (rank : 66)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	109	Target Neighborhood Hits	414	Shared Neighborhood Hits	16
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

YTDC2_HUMAN
NC score	0.020519 (rank : 67)	θ value	1.06291 (rank : 37)
Query Neighborhood Hits	109	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H6S0	Gene names	YTHDC2
Domain Architecture	No domain graphic available
Description	YTH domain-containing protein 2.

FBX10_HUMAN
NC score	0.020080 (rank : 68)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	109	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UK96, Q5JRT8, Q9UKC3	Gene names	FBXO10, FBX10
Domain Architecture	No domain graphic available
Description	F-box only protein 10.

OAZ1_MOUSE
NC score	0.019539 (rank : 69)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	109	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P54369, O08610	Gene names	Oaz1, Oaz
Domain Architecture
Description	Ornithine decarboxylase antizyme (ODC-Az).

MYO10_HUMAN
NC score	0.019459 (rank : 70)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	109	Target Neighborhood Hits	920	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

SMAL1_HUMAN
NC score	0.019016 (rank : 71)	θ value	1.81305 (rank : 44)
Query Neighborhood Hits	109	Target Neighborhood Hits	174	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

NNP1_MOUSE
NC score	0.018302 (rank : 72)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	109	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	P56183, O35712, Q9ERE1, Q9JI07, Q9JK67, Q9JKU2	Gene names	Nnp1
Domain Architecture
Description	NNP-1 protein (Novel nuclear protein 1) (Nop52).

SPRE3_MOUSE
NC score	0.018127 (rank : 73)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	109	Target Neighborhood Hits	111	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P6N5, Q7TNJ8	Gene names	Spred3
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 3 (Spred-3).

ABCA1_MOUSE
NC score	0.018081 (rank : 74)	θ value	0.47712 (rank : 24)
Query Neighborhood Hits	109	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	P41233	Gene names	Abca1, Abc1
Domain Architecture
Description	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ATP-binding cassette 1) (ABC-1).

CM007_MOUSE
NC score	0.017714 (rank : 75)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	109	Target Neighborhood Hits	416	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

ABCA1_HUMAN
NC score	0.017070 (rank : 76)	θ value	1.06291 (rank : 34)
Query Neighborhood Hits	109	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	O95477, Q96S56, Q96T85, Q9NQV4, Q9UN06, Q9UN07, Q9UN08, Q9UN09	Gene names	ABCA1, ABC1, CERP
Domain Architecture
Description	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ATP-binding cassette 1) (ABC-1) (Cholesterol efflux regulatory protein).

CRTC1_HUMAN
NC score	0.016243 (rank : 77)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	109	Target Neighborhood Hits	319	Shared Neighborhood Hits	13
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

TDRD3_MOUSE
NC score	0.015400 (rank : 78)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	109	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q91W18, Q8BZW6	Gene names	Tdrd3
Domain Architecture
Description	Tudor domain-containing protein 3.

RAI1_HUMAN
NC score	0.015064 (rank : 79)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	109	Target Neighborhood Hits	360	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

LRRF2_MOUSE
NC score	0.014654 (rank : 80)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	109	Target Neighborhood Hits	556	Shared Neighborhood Hits	8
SwissProt Accessions	Q91WK0, Q8BVD1, Q9CU89	Gene names	Lrrfip2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

ULK2_HUMAN
NC score	0.013893 (rank : 81)	θ value	0.0431538 (rank : 19)
Query Neighborhood Hits	109	Target Neighborhood Hits	979	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

CSKI2_HUMAN
NC score	0.013483 (rank : 82)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	109	Target Neighborhood Hits	747	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

PCLO_HUMAN
NC score	0.013335 (rank : 83)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	109	Target Neighborhood Hits	2046	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SMAL1_MOUSE
NC score	0.013210 (rank : 84)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	109	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

SPEG_MOUSE
NC score	0.012809 (rank : 85)	θ value	1.81305 (rank : 45)
Query Neighborhood Hits	109	Target Neighborhood Hits	1959	Shared Neighborhood Hits	39
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

GP124_MOUSE
NC score	0.012621 (rank : 86)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	109	Target Neighborhood Hits	423	Shared Neighborhood Hits	9
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

RP1L1_MOUSE
NC score	0.012212 (rank : 87)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	109	Target Neighborhood Hits	170	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

CBL_HUMAN
NC score	0.012053 (rank : 88)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	109	Target Neighborhood Hits	353	Shared Neighborhood Hits	11
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

SEM6C_MOUSE
NC score	0.011841 (rank : 89)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	109	Target Neighborhood Hits	352	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

LRRF2_HUMAN
NC score	0.011248 (rank : 90)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	109	Target Neighborhood Hits	791	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

NOVA1_HUMAN
NC score	0.011010 (rank : 91)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	109	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	P51513	Gene names	NOVA1
Domain Architecture
Description	RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Onconeural ventral antigen 1) (Paraneoplastic Ri antigen) (Ventral neuron-specific protein 1).

IBP2_HUMAN
NC score	0.010819 (rank : 92)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	109	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	P18065, Q14619, Q9UCL3	Gene names	IGFBP2, BP2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

NGN2_MOUSE
NC score	0.010517 (rank : 93)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	109	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	P70447, P70237	Gene names	Neurog2, Ath4a, Atoh4, Ngn2
Domain Architecture
Description	Neurogenin 2 (Atonal protein homolog 4) (Helix-loop-helix protein mATH-4A) (MATH4A).

SYCP1_HUMAN
NC score	0.009993 (rank : 94)	θ value	2.36792 (rank : 52)
Query Neighborhood Hits	109	Target Neighborhood Hits	1313	Shared Neighborhood Hits	16
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

BAZ2A_MOUSE
NC score	0.009473 (rank : 95)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	109	Target Neighborhood Hits	744	Shared Neighborhood Hits	25
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

GLI1_HUMAN
NC score	0.008434 (rank : 96)	θ value	0.62314 (rank : 27)
Query Neighborhood Hits	109	Target Neighborhood Hits	828	Shared Neighborhood Hits	13
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

ARBK1_MOUSE
NC score	0.008370 (rank : 97)	θ value	1.81305 (rank : 43)
Query Neighborhood Hits	109	Target Neighborhood Hits	849	Shared Neighborhood Hits	11
SwissProt Accessions	Q99MK8, Q99LL8	Gene names	Adrbk1, Grk2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein-coupled receptor kinase 2).

ARBK1_HUMAN
NC score	0.007886 (rank : 98)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	109	Target Neighborhood Hits	859	Shared Neighborhood Hits	11
SwissProt Accessions	P25098, Q13837	Gene names	ADRBK1, BARK, BARK1, GRK2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein coupled receptor kinase 2).

ULK2_MOUSE
NC score	0.007450 (rank : 99)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	109	Target Neighborhood Hits	943	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QY01, Q80TV7, Q9WTP4	Gene names	Ulk2, Kiaa0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2).

GTR8_MOUSE
NC score	0.007123 (rank : 100)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	109	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JIF3, Q9JJP4, Q9JJZ0	Gene names	Slc2a8, Glut8, GlutX1
Domain Architecture
Description	Solute carrier family 2, facilitated glucose transporter member 8 (Glucose transporter type 8) (Glucose transporter type X1).

INHBE_MOUSE
NC score	0.006868 (rank : 101)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	109	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	O08717	Gene names	Inhbe
Domain Architecture
Description	Inhibin beta E chain precursor (Activin beta-E chain).

TGIF_HUMAN
NC score	0.006765 (rank : 102)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	Q15583, Q6ICR0, Q8N5X9, Q9NRS0	Gene names	TGIF
Domain Architecture
Description	5'-TG-3'-interacting factor (Homeobox protein TGIF).

HXD8_MOUSE
NC score	0.006559 (rank : 103)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	109	Target Neighborhood Hits	333	Shared Neighborhood Hits	3
SwissProt Accessions	P23463	Gene names	Hoxd8, Hox-4.3, Hoxd-8
Domain Architecture
Description	Homeobox protein Hox-D8 (Hox-4.3) (Hox-5.4).

TTBK1_HUMAN
NC score	0.006075 (rank : 104)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	109	Target Neighborhood Hits	1058	Shared Neighborhood Hits	21
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

T2R41_HUMAN
NC score	0.006072 (rank : 105)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	109	Target Neighborhood Hits	77	Shared Neighborhood Hits	3
SwissProt Accessions	P59536, P59550	Gene names	TAS2R41
Domain Architecture
Description	Taste receptor type 2 member 41 (T2R41) (T2R59).

PAR3L_HUMAN
NC score	0.005977 (rank : 106)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	109	Target Neighborhood Hits	297	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

AGRIN_HUMAN
NC score	0.005491 (rank : 107)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	109	Target Neighborhood Hits	582	Shared Neighborhood Hits	6
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

KLF17_MOUSE
NC score	0.005346 (rank : 108)	θ value	0.279714 (rank : 23)
Query Neighborhood Hits	109	Target Neighborhood Hits	684	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CFA7, Q3UT30, Q6P233, Q9D351	Gene names	Klf17, Gzf, Zfp393, Znf393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393) (Germ cell-specific zinc finger protein).

TRIO_HUMAN
NC score	0.005152 (rank : 109)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	109	Target Neighborhood Hits	1580	Shared Neighborhood Hits	21
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

TMF1_HUMAN
NC score	0.004321 (rank : 110)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	109	Target Neighborhood Hits	987	Shared Neighborhood Hits	12
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

APOA_HUMAN
NC score	0.004214 (rank : 111)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	109	Target Neighborhood Hits	221	Shared Neighborhood Hits	2
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

MTR1L_MOUSE
NC score	0.004162 (rank : 112)	θ value	0.62314 (rank : 29)
Query Neighborhood Hits	109	Target Neighborhood Hits	903	Shared Neighborhood Hits	2
SwissProt Accessions	O88495	Gene names	Gpr50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

SSPO_MOUSE
NC score	0.003685 (rank : 113)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	109	Target Neighborhood Hits	800	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

DSCAM_HUMAN
NC score	0.003010 (rank : 114)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	109	Target Neighborhood Hits	524	Shared Neighborhood Hits	7
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).