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Network neighborhood for query Sequence : DOK1_MOUSE

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DOK1_MOUSE
SwissProt Accessions	P97465, Q9R213	Gene names	Dok1, Dok
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DOK1_HUMAN
θ value	0 (rank : 1)	NC score	0.972098 (rank : 2)
Query Neighborhood Hits	82	Target Neighborhood Hits	85	Shared Neighborhood Hits	26
SwissProt Accessions	Q99704, O43204, Q9UHG6	Gene names	DOK1
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62).

DOK1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	82	Target Neighborhood Hits	82	Shared Neighborhood Hits	82
SwissProt Accessions	P97465, Q9R213	Gene names	Dok1, Dok
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)).

DOK2_MOUSE
θ value	5.7518e-47 (rank : 3)	NC score	0.840482 (rank : 6)
Query Neighborhood Hits	82	Target Neighborhood Hits	244	Shared Neighborhood Hits	36
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

DOK2_HUMAN
θ value	4.122e-45 (rank : 4)	NC score	0.889051 (rank : 3)
Query Neighborhood Hits	82	Target Neighborhood Hits	46	Shared Neighborhood Hits	18
SwissProt Accessions	O60496	Gene names	DOK2
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)).

DOK3_MOUSE
θ value	7.03111e-45 (rank : 5)	NC score	0.884402 (rank : 4)
Query Neighborhood Hits	82	Target Neighborhood Hits	25	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QZK7	Gene names	Dok3, Dokl
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3) (P62(dok)-like protein) (DOK-L).

DOK3_HUMAN
θ value	2.67181e-44 (rank : 6)	NC score	0.872143 (rank : 5)
Query Neighborhood Hits	82	Target Neighborhood Hits	60	Shared Neighborhood Hits	18
SwissProt Accessions	Q7L591, Q8N864, Q9BQB3, Q9H666	Gene names	DOK3
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3).

DOK6_HUMAN
θ value	1.33837e-11 (rank : 7)	NC score	0.577749 (rank : 7)
Query Neighborhood Hits	82	Target Neighborhood Hits	25	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PKX4, Q4V9S3, Q8WUZ8, Q96HI2, Q96LU2	Gene names	DOK6, DOK5L
Domain Architecture	No domain graphic available
Description	Docking protein 6 (Downstream of tyrosine kinase 6).

DOK4_HUMAN
θ value	5.08577e-11 (rank : 8)	NC score	0.563435 (rank : 10)
Query Neighborhood Hits	82	Target Neighborhood Hits	28	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TEW6, O75209, Q9BTP2, Q9NVV3	Gene names	DOK4
Domain Architecture	No domain graphic available
Description	Docking protein 4 (Downstream of tyrosine kinase 4).

DOK4_MOUSE
θ value	5.08577e-11 (rank : 9)	NC score	0.562240 (rank : 11)
Query Neighborhood Hits	82	Target Neighborhood Hits	30	Shared Neighborhood Hits	17
SwissProt Accessions	Q99KE3, Q3U0X3	Gene names	Dok4
Domain Architecture	No domain graphic available
Description	Docking protein 4 (Downstream of tyrosine kinase 4).

FRS3_HUMAN
θ value	4.30538e-10 (rank : 10)	NC score	0.519437 (rank : 12)
Query Neighborhood Hits	82	Target Neighborhood Hits	76	Shared Neighborhood Hits	19
SwissProt Accessions	O43559, Q5T3D5	Gene names	FRS3
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (Suc1-associated neurotrophic factor target 2) (SNT-2) (FGFR signaling adaptor SNT2).

FRS3_MOUSE
θ value	4.30538e-10 (rank : 11)	NC score	0.515626 (rank : 13)
Query Neighborhood Hits	82	Target Neighborhood Hits	168	Shared Neighborhood Hits	27
SwissProt Accessions	Q91WJ0	Gene names	Frs3, Frs2b
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FRS2-beta).

DOK5_HUMAN
θ value	7.34386e-10 (rank : 12)	NC score	0.568434 (rank : 9)
Query Neighborhood Hits	82	Target Neighborhood Hits	28	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P104, Q5T7Y0, Q5TE53, Q8TEW7, Q96H13, Q9BZ24, Q9NQF4, Q9Y411	Gene names	DOK5, C20orf180
Domain Architecture
Description	Docking protein 5 (Downstream of tyrosine kinase 5) (IRS6) (Protein dok-5).

DOK5_MOUSE
θ value	7.34386e-10 (rank : 13)	NC score	0.568768 (rank : 8)
Query Neighborhood Hits	82	Target Neighborhood Hits	27	Shared Neighborhood Hits	17
SwissProt Accessions	Q91ZM9, Q8BRI3, Q9CSM6	Gene names	Dok5
Domain Architecture
Description	Docking protein 5 (Downstream of tyrosine kinase 5) (Protein dok-5).

FRS2_MOUSE
θ value	8.97725e-08 (rank : 14)	NC score	0.492911 (rank : 14)
Query Neighborhood Hits	82	Target Neighborhood Hits	41	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C180	Gene names	Frs2, Frs2a
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (Suc1-associated neurotrophic factor target 1) (SNT-1) (FGFR signaling adaptor SNT) (FRS2 alpha).

FRS2_HUMAN
θ value	1.17247e-07 (rank : 15)	NC score	0.491116 (rank : 15)
Query Neighborhood Hits	82	Target Neighborhood Hits	40	Shared Neighborhood Hits	17
SwissProt Accessions	Q8WU20, O43558, Q7LDQ6	Gene names	FRS2
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (Suc1-associated neurotrophic factor target 1) (SNT-1) (FGFR signaling adaptor SNT).

SHD_HUMAN
θ value	0.0330416 (rank : 16)	NC score	0.054004 (rank : 19)
Query Neighborhood Hits	82	Target Neighborhood Hits	204	Shared Neighborhood Hits	7
SwissProt Accessions	Q96IW2, Q96NC2	Gene names	SHD
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

RAI1_MOUSE
θ value	0.0563607 (rank : 17)	NC score	0.052563 (rank : 21)
Query Neighborhood Hits	82	Target Neighborhood Hits	344	Shared Neighborhood Hits	13
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

GRLF1_HUMAN
θ value	0.163984 (rank : 18)	NC score	0.024164 (rank : 60)
Query Neighborhood Hits	82	Target Neighborhood Hits	167	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

MLL4_HUMAN
θ value	0.279714 (rank : 19)	NC score	0.044484 (rank : 26)
Query Neighborhood Hits	82	Target Neighborhood Hits	722	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

CO039_MOUSE
θ value	0.365318 (rank : 20)	NC score	0.043807 (rank : 28)
Query Neighborhood Hits	82	Target Neighborhood Hits	445	Shared Neighborhood Hits	20
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

AFF1_MOUSE
θ value	0.62314 (rank : 21)	NC score	0.035889 (rank : 37)
Query Neighborhood Hits	82	Target Neighborhood Hits	351	Shared Neighborhood Hits	14
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

CASL_MOUSE
θ value	0.62314 (rank : 22)	NC score	0.034621 (rank : 38)
Query Neighborhood Hits	82	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

DOK7_HUMAN
θ value	0.813845 (rank : 23)	NC score	0.192802 (rank : 16)
Query Neighborhood Hits	82	Target Neighborhood Hits	51	Shared Neighborhood Hits	19
SwissProt Accessions	Q18PE1, Q6P6A6, Q86XG5, Q8N2J3, Q8NBC1	Gene names	DOK7, C4orf25
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

ESPL1_MOUSE
θ value	0.813845 (rank : 24)	NC score	0.030361 (rank : 45)
Query Neighborhood Hits	82	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	P60330	Gene names	Espl1, Esp1, Kiaa0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

FMNL_MOUSE
θ value	0.813845 (rank : 25)	NC score	0.038976 (rank : 31)
Query Neighborhood Hits	82	Target Neighborhood Hits	428	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

PDC6I_HUMAN
θ value	0.813845 (rank : 26)	NC score	0.038406 (rank : 33)
Query Neighborhood Hits	82	Target Neighborhood Hits	278	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

KCNK4_HUMAN
θ value	1.06291 (rank : 27)	NC score	0.018359 (rank : 63)
Query Neighborhood Hits	82	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

RBBP6_HUMAN
θ value	1.06291 (rank : 28)	NC score	0.028873 (rank : 46)
Query Neighborhood Hits	82	Target Neighborhood Hits	1135	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	1.06291 (rank : 29)	NC score	0.031476 (rank : 43)
Query Neighborhood Hits	82	Target Neighborhood Hits	1014	Shared Neighborhood Hits	14
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

YLPM1_HUMAN
θ value	1.06291 (rank : 30)	NC score	0.032763 (rank : 42)
Query Neighborhood Hits	82	Target Neighborhood Hits	670	Shared Neighborhood Hits	22
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

GPSM3_MOUSE
θ value	1.38821 (rank : 31)	NC score	0.042650 (rank : 29)
Query Neighborhood Hits	82	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q3U1Z5, Q3U1M8, Q3UJZ5, Q8VDF9	Gene names	Gpsm3
Domain Architecture	No domain graphic available
Description	G-protein signaling modulator 3.

HXA3_MOUSE
θ value	1.38821 (rank : 32)	NC score	0.009625 (rank : 75)
Query Neighborhood Hits	82	Target Neighborhood Hits	558	Shared Neighborhood Hits	10
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

PDC6I_MOUSE
θ value	1.38821 (rank : 33)	NC score	0.036170 (rank : 36)
Query Neighborhood Hits	82	Target Neighborhood Hits	275	Shared Neighborhood Hits	9
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

SIN3B_HUMAN
θ value	1.38821 (rank : 34)	NC score	0.020966 (rank : 61)
Query Neighborhood Hits	82	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	O75182, Q68GC2, Q6P4B8, Q8TB34, Q9BSC8	Gene names	SIN3B, KIAA0700
Domain Architecture
Description	Paired amphipathic helix protein Sin3b (Transcriptional corepressor Sin3b) (Histone deacetylase complex subunit Sin3b).

UBP42_HUMAN
θ value	1.38821 (rank : 35)	NC score	0.015771 (rank : 66)
Query Neighborhood Hits	82	Target Neighborhood Hits	445	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

OGFR_HUMAN
θ value	1.81305 (rank : 36)	NC score	0.038944 (rank : 32)
Query Neighborhood Hits	82	Target Neighborhood Hits	1582	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

RPGF6_HUMAN
θ value	1.81305 (rank : 37)	NC score	0.025066 (rank : 57)
Query Neighborhood Hits	82	Target Neighborhood Hits	266	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

SFR15_HUMAN
θ value	1.81305 (rank : 38)	NC score	0.033069 (rank : 40)
Query Neighborhood Hits	82	Target Neighborhood Hits	368	Shared Neighborhood Hits	14
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

WASIP_MOUSE
θ value	1.81305 (rank : 39)	NC score	0.036461 (rank : 35)
Query Neighborhood Hits	82	Target Neighborhood Hits	392	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

DOK7_MOUSE
θ value	2.36792 (rank : 40)	NC score	0.173881 (rank : 17)
Query Neighborhood Hits	82	Target Neighborhood Hits	169	Shared Neighborhood Hits	24
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

FMNL_HUMAN
θ value	2.36792 (rank : 41)	NC score	0.045220 (rank : 25)
Query Neighborhood Hits	82	Target Neighborhood Hits	529	Shared Neighborhood Hits	19
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

HIC1_MOUSE
θ value	2.36792 (rank : 42)	NC score	0.000109 (rank : 84)
Query Neighborhood Hits	82	Target Neighborhood Hits	863	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

RXRB_HUMAN
θ value	2.36792 (rank : 43)	NC score	0.012670 (rank : 70)
Query Neighborhood Hits	82	Target Neighborhood Hits	280	Shared Neighborhood Hits	8
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

TDPZ1_MOUSE
θ value	2.36792 (rank : 44)	NC score	0.013864 (rank : 68)
Query Neighborhood Hits	82	Target Neighborhood Hits	164	Shared Neighborhood Hits	4
SwissProt Accessions	Q717B3, Q71G58, Q8BZV7, Q8VI39	Gene names	Tdpoz1, 2cpoz56, Mapp2, Spopl1
Domain Architecture	No domain graphic available
Description	TD and POZ domain-containing protein 1 (MAPP family protein 2).

PRB4S_HUMAN
θ value	3.0926 (rank : 45)	NC score	0.027423 (rank : 51)
Query Neighborhood Hits	82	Target Neighborhood Hits	330	Shared Neighborhood Hits	10
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PS1C2_MOUSE
θ value	3.0926 (rank : 46)	NC score	0.045841 (rank : 24)
Query Neighborhood Hits	82	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q80ZC9	Gene names	Psors1c2, Spr1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein homolog precursor (SPR1 protein).

SF01_MOUSE
θ value	3.0926 (rank : 47)	NC score	0.028595 (rank : 48)
Query Neighborhood Hits	82	Target Neighborhood Hits	240	Shared Neighborhood Hits	11
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

ATS19_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.005652 (rank : 82)
Query Neighborhood Hits	82	Target Neighborhood Hits	203	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

DIAP2_HUMAN
θ value	4.03905 (rank : 49)	NC score	0.024545 (rank : 59)
Query Neighborhood Hits	82	Target Neighborhood Hits	342	Shared Neighborhood Hits	16
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

EFS_HUMAN
θ value	4.03905 (rank : 50)	NC score	0.025270 (rank : 56)
Query Neighborhood Hits	82	Target Neighborhood Hits	348	Shared Neighborhood Hits	12
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

FMN2_MOUSE
θ value	4.03905 (rank : 51)	NC score	0.041801 (rank : 30)
Query Neighborhood Hits	82	Target Neighborhood Hits	349	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

MLL3_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.025020 (rank : 58)
Query Neighborhood Hits	82	Target Neighborhood Hits	1644	Shared Neighborhood Hits	41
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PI5PA_HUMAN
θ value	4.03905 (rank : 53)	NC score	0.032861 (rank : 41)
Query Neighborhood Hits	82	Target Neighborhood Hits	749	Shared Neighborhood Hits	34
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

RXRB_MOUSE
θ value	4.03905 (rank : 54)	NC score	0.010682 (rank : 74)
Query Neighborhood Hits	82	Target Neighborhood Hits	230	Shared Neighborhood Hits	9
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

SF01_HUMAN
θ value	4.03905 (rank : 55)	NC score	0.026434 (rank : 54)
Query Neighborhood Hits	82	Target Neighborhood Hits	287	Shared Neighborhood Hits	11
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF3A1_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.026958 (rank : 53)
Query Neighborhood Hits	82	Target Neighborhood Hits	199	Shared Neighborhood Hits	7
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

SF3A1_MOUSE
θ value	4.03905 (rank : 57)	NC score	0.027123 (rank : 52)
Query Neighborhood Hits	82	Target Neighborhood Hits	198	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

SON_MOUSE
θ value	4.03905 (rank : 58)	NC score	0.020144 (rank : 62)
Query Neighborhood Hits	82	Target Neighborhood Hits	957	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

WBP11_HUMAN
θ value	4.03905 (rank : 59)	NC score	0.036943 (rank : 34)
Query Neighborhood Hits	82	Target Neighborhood Hits	354	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

CAC1H_MOUSE
θ value	5.27518 (rank : 60)	NC score	0.006445 (rank : 81)
Query Neighborhood Hits	82	Target Neighborhood Hits	230	Shared Neighborhood Hits	7
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CASL_HUMAN
θ value	5.27518 (rank : 61)	NC score	0.028198 (rank : 50)
Query Neighborhood Hits	82	Target Neighborhood Hits	259	Shared Neighborhood Hits	10
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

DAAM1_HUMAN
θ value	5.27518 (rank : 62)	NC score	0.026053 (rank : 55)
Query Neighborhood Hits	82	Target Neighborhood Hits	483	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

FMN2_HUMAN
θ value	5.27518 (rank : 63)	NC score	0.028794 (rank : 47)
Query Neighborhood Hits	82	Target Neighborhood Hits	484	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

HXA3_HUMAN
θ value	5.27518 (rank : 64)	NC score	0.008068 (rank : 77)
Query Neighborhood Hits	82	Target Neighborhood Hits	535	Shared Neighborhood Hits	11
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

PRR12_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.044325 (rank : 27)
Query Neighborhood Hits	82	Target Neighborhood Hits	460	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

DOCK3_MOUSE
θ value	6.88961 (rank : 66)	NC score	0.006972 (rank : 79)
Query Neighborhood Hits	82	Target Neighborhood Hits	93	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CIQ7	Gene names	Dock3, Moca
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

ENAH_MOUSE
θ value	6.88961 (rank : 67)	NC score	0.034330 (rank : 39)
Query Neighborhood Hits	82	Target Neighborhood Hits	919	Shared Neighborhood Hits	18
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

PLS1_MOUSE
θ value	6.88961 (rank : 68)	NC score	0.016852 (rank : 64)
Query Neighborhood Hits	82	Target Neighborhood Hits	58	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JJ00, O54730, O54731, Q9D1F8	Gene names	Plscr1, Tra1b, Tras1
Domain Architecture
Description	Phospholipid scramblase 1 (PL scramblase 1) (Ca(2+)-dependent phospholipid scramblase 1) (Transplantability-associated protein 1) (TRA1) (NOR1).

WASIP_HUMAN
θ value	6.88961 (rank : 69)	NC score	0.031085 (rank : 44)
Query Neighborhood Hits	82	Target Neighborhood Hits	458	Shared Neighborhood Hits	18
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

ARX_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.002760 (rank : 83)
Query Neighborhood Hits	82	Target Neighborhood Hits	401	Shared Neighborhood Hits	5
SwissProt Accessions	Q96QS3	Gene names	ARX
Domain Architecture
Description	Homeobox protein ARX (Aristaless-related homeobox).

BCAR1_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.050053 (rank : 23)
Query Neighborhood Hits	82	Target Neighborhood Hits	554	Shared Neighborhood Hits	30
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CD2_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.028372 (rank : 49)
Query Neighborhood Hits	82	Target Neighborhood Hits	504	Shared Neighborhood Hits	32
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CRTC1_HUMAN
θ value	8.99809 (rank : 73)	NC score	0.016186 (rank : 65)
Query Neighborhood Hits	82	Target Neighborhood Hits	319	Shared Neighborhood Hits	20
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

EGFR_HUMAN
θ value	8.99809 (rank : 74)	NC score	-0.002146 (rank : 85)
Query Neighborhood Hits	82	Target Neighborhood Hits	939	Shared Neighborhood Hits	2
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

JPH2_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.014732 (rank : 67)
Query Neighborhood Hits	82	Target Neighborhood Hits	639	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

LSD1_MOUSE
θ value	8.99809 (rank : 76)	NC score	0.008269 (rank : 76)
Query Neighborhood Hits	82	Target Neighborhood Hits	224	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

RANB9_HUMAN
θ value	8.99809 (rank : 77)	NC score	0.012100 (rank : 71)
Query Neighborhood Hits	82	Target Neighborhood Hits	179	Shared Neighborhood Hits	8
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

RC3H1_MOUSE
θ value	8.99809 (rank : 78)	NC score	0.007048 (rank : 78)
Query Neighborhood Hits	82	Target Neighborhood Hits	244	Shared Neighborhood Hits	4
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

STAP2_HUMAN
θ value	8.99809 (rank : 79)	NC score	0.011377 (rank : 72)
Query Neighborhood Hits	82	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UGK3, Q9NXI2	Gene names	STAP2, BKS
Domain Architecture	No domain graphic available
Description	Signal-transducing adaptor protein 2 (STAP-2) (Breast tumor kinase substrate) (BRK substrate).

SUZ12_HUMAN
θ value	8.99809 (rank : 80)	NC score	0.011070 (rank : 73)
Query Neighborhood Hits	82	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q15022, Q96BD9	Gene names	SUZ12, CHET9, JJAZ1, KIAA0160
Domain Architecture	No domain graphic available
Description	Polycomb protein SUZ12 (Suppressor of zeste 12 protein homolog) (Joined to JAZF1 protein) (Chromatin precipitated E2F target 9 protein) (ChET 9 protein).

TACC2_MOUSE
θ value	8.99809 (rank : 81)	NC score	0.006945 (rank : 80)
Query Neighborhood Hits	82	Target Neighborhood Hits	774	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

ZCHC8_MOUSE
θ value	8.99809 (rank : 82)	NC score	0.012824 (rank : 69)
Query Neighborhood Hits	82	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CYA6, Q3TK71, Q8CCB7, Q91WQ1	Gene names	Zcchc8
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 8.

IRS1_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.053553 (rank : 20)
Query Neighborhood Hits	82	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

IRS1_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.065919 (rank : 18)
Query Neighborhood Hits	82	Target Neighborhood Hits	112	Shared Neighborhood Hits	8
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

PELP1_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.052221 (rank : 22)
Query Neighborhood Hits	82	Target Neighborhood Hits	709	Shared Neighborhood Hits	33
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

Hits sorted by NC score

DOK1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	82	Target Neighborhood Hits	82	Shared Neighborhood Hits	82
SwissProt Accessions	P97465, Q9R213	Gene names	Dok1, Dok
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)).

DOK1_HUMAN
NC score	0.972098 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	82	Target Neighborhood Hits	85	Shared Neighborhood Hits	26
SwissProt Accessions	Q99704, O43204, Q9UHG6	Gene names	DOK1
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62).

DOK2_HUMAN
NC score	0.889051 (rank : 3)	θ value	4.122e-45 (rank : 4)
Query Neighborhood Hits	82	Target Neighborhood Hits	46	Shared Neighborhood Hits	18
SwissProt Accessions	O60496	Gene names	DOK2
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)).

DOK3_MOUSE
NC score	0.884402 (rank : 4)	θ value	7.03111e-45 (rank : 5)
Query Neighborhood Hits	82	Target Neighborhood Hits	25	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QZK7	Gene names	Dok3, Dokl
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3) (P62(dok)-like protein) (DOK-L).

DOK3_HUMAN
NC score	0.872143 (rank : 5)	θ value	2.67181e-44 (rank : 6)
Query Neighborhood Hits	82	Target Neighborhood Hits	60	Shared Neighborhood Hits	18
SwissProt Accessions	Q7L591, Q8N864, Q9BQB3, Q9H666	Gene names	DOK3
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3).

DOK2_MOUSE
NC score	0.840482 (rank : 6)	θ value	5.7518e-47 (rank : 3)
Query Neighborhood Hits	82	Target Neighborhood Hits	244	Shared Neighborhood Hits	36
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

DOK6_HUMAN
NC score	0.577749 (rank : 7)	θ value	1.33837e-11 (rank : 7)
Query Neighborhood Hits	82	Target Neighborhood Hits	25	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PKX4, Q4V9S3, Q8WUZ8, Q96HI2, Q96LU2	Gene names	DOK6, DOK5L
Domain Architecture	No domain graphic available
Description	Docking protein 6 (Downstream of tyrosine kinase 6).

DOK5_MOUSE
NC score	0.568768 (rank : 8)	θ value	7.34386e-10 (rank : 13)
Query Neighborhood Hits	82	Target Neighborhood Hits	27	Shared Neighborhood Hits	17
SwissProt Accessions	Q91ZM9, Q8BRI3, Q9CSM6	Gene names	Dok5
Domain Architecture
Description	Docking protein 5 (Downstream of tyrosine kinase 5) (Protein dok-5).

DOK5_HUMAN
NC score	0.568434 (rank : 9)	θ value	7.34386e-10 (rank : 12)
Query Neighborhood Hits	82	Target Neighborhood Hits	28	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P104, Q5T7Y0, Q5TE53, Q8TEW7, Q96H13, Q9BZ24, Q9NQF4, Q9Y411	Gene names	DOK5, C20orf180
Domain Architecture
Description	Docking protein 5 (Downstream of tyrosine kinase 5) (IRS6) (Protein dok-5).

DOK4_HUMAN
NC score	0.563435 (rank : 10)	θ value	5.08577e-11 (rank : 8)
Query Neighborhood Hits	82	Target Neighborhood Hits	28	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TEW6, O75209, Q9BTP2, Q9NVV3	Gene names	DOK4
Domain Architecture	No domain graphic available
Description	Docking protein 4 (Downstream of tyrosine kinase 4).

DOK4_MOUSE
NC score	0.562240 (rank : 11)	θ value	5.08577e-11 (rank : 9)
Query Neighborhood Hits	82	Target Neighborhood Hits	30	Shared Neighborhood Hits	17
SwissProt Accessions	Q99KE3, Q3U0X3	Gene names	Dok4
Domain Architecture	No domain graphic available
Description	Docking protein 4 (Downstream of tyrosine kinase 4).

FRS3_HUMAN
NC score	0.519437 (rank : 12)	θ value	4.30538e-10 (rank : 10)
Query Neighborhood Hits	82	Target Neighborhood Hits	76	Shared Neighborhood Hits	19
SwissProt Accessions	O43559, Q5T3D5	Gene names	FRS3
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (Suc1-associated neurotrophic factor target 2) (SNT-2) (FGFR signaling adaptor SNT2).

FRS3_MOUSE
NC score	0.515626 (rank : 13)	θ value	4.30538e-10 (rank : 11)
Query Neighborhood Hits	82	Target Neighborhood Hits	168	Shared Neighborhood Hits	27
SwissProt Accessions	Q91WJ0	Gene names	Frs3, Frs2b
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FRS2-beta).

FRS2_MOUSE
NC score	0.492911 (rank : 14)	θ value	8.97725e-08 (rank : 14)
Query Neighborhood Hits	82	Target Neighborhood Hits	41	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C180	Gene names	Frs2, Frs2a
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (Suc1-associated neurotrophic factor target 1) (SNT-1) (FGFR signaling adaptor SNT) (FRS2 alpha).

FRS2_HUMAN
NC score	0.491116 (rank : 15)	θ value	1.17247e-07 (rank : 15)
Query Neighborhood Hits	82	Target Neighborhood Hits	40	Shared Neighborhood Hits	17
SwissProt Accessions	Q8WU20, O43558, Q7LDQ6	Gene names	FRS2
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (Suc1-associated neurotrophic factor target 1) (SNT-1) (FGFR signaling adaptor SNT).

DOK7_HUMAN
NC score	0.192802 (rank : 16)	θ value	0.813845 (rank : 23)
Query Neighborhood Hits	82	Target Neighborhood Hits	51	Shared Neighborhood Hits	19
SwissProt Accessions	Q18PE1, Q6P6A6, Q86XG5, Q8N2J3, Q8NBC1	Gene names	DOK7, C4orf25
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

DOK7_MOUSE
NC score	0.173881 (rank : 17)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	82	Target Neighborhood Hits	169	Shared Neighborhood Hits	24
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

IRS1_MOUSE
NC score	0.065919 (rank : 18)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	82	Target Neighborhood Hits	112	Shared Neighborhood Hits	8
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

SHD_HUMAN
NC score	0.054004 (rank : 19)	θ value	0.0330416 (rank : 16)
Query Neighborhood Hits	82	Target Neighborhood Hits	204	Shared Neighborhood Hits	7
SwissProt Accessions	Q96IW2, Q96NC2	Gene names	SHD
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

IRS1_HUMAN
NC score	0.053553 (rank : 20)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	82	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

RAI1_MOUSE
NC score	0.052563 (rank : 21)	θ value	0.0563607 (rank : 17)
Query Neighborhood Hits	82	Target Neighborhood Hits	344	Shared Neighborhood Hits	13
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

PELP1_MOUSE
NC score	0.052221 (rank : 22)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	82	Target Neighborhood Hits	709	Shared Neighborhood Hits	33
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

BCAR1_HUMAN
NC score	0.050053 (rank : 23)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	82	Target Neighborhood Hits	554	Shared Neighborhood Hits	30
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

PS1C2_MOUSE
NC score	0.045841 (rank : 24)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	82	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q80ZC9	Gene names	Psors1c2, Spr1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein homolog precursor (SPR1 protein).

FMNL_HUMAN
NC score	0.045220 (rank : 25)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	82	Target Neighborhood Hits	529	Shared Neighborhood Hits	19
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

MLL4_HUMAN
NC score	0.044484 (rank : 26)	θ value	0.279714 (rank : 19)
Query Neighborhood Hits	82	Target Neighborhood Hits	722	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

PRR12_HUMAN
NC score	0.044325 (rank : 27)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	82	Target Neighborhood Hits	460	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

CO039_MOUSE
NC score	0.043807 (rank : 28)	θ value	0.365318 (rank : 20)
Query Neighborhood Hits	82	Target Neighborhood Hits	445	Shared Neighborhood Hits	20
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

GPSM3_MOUSE
NC score	0.042650 (rank : 29)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	82	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q3U1Z5, Q3U1M8, Q3UJZ5, Q8VDF9	Gene names	Gpsm3
Domain Architecture	No domain graphic available
Description	G-protein signaling modulator 3.

FMN2_MOUSE
NC score	0.041801 (rank : 30)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	82	Target Neighborhood Hits	349	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

FMNL_MOUSE
NC score	0.038976 (rank : 31)	θ value	0.813845 (rank : 25)
Query Neighborhood Hits	82	Target Neighborhood Hits	428	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

OGFR_HUMAN
NC score	0.038944 (rank : 32)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	82	Target Neighborhood Hits	1582	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PDC6I_HUMAN
NC score	0.038406 (rank : 33)	θ value	0.813845 (rank : 26)
Query Neighborhood Hits	82	Target Neighborhood Hits	278	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

WBP11_HUMAN
NC score	0.036943 (rank : 34)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	82	Target Neighborhood Hits	354	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WASIP_MOUSE
NC score	0.036461 (rank : 35)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	82	Target Neighborhood Hits	392	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

PDC6I_MOUSE
NC score	0.036170 (rank : 36)	θ value	1.38821 (rank : 33)
Query Neighborhood Hits	82	Target Neighborhood Hits	275	Shared Neighborhood Hits	9
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

AFF1_MOUSE
NC score	0.035889 (rank : 37)	θ value	0.62314 (rank : 21)
Query Neighborhood Hits	82	Target Neighborhood Hits	351	Shared Neighborhood Hits	14
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

CASL_MOUSE
NC score	0.034621 (rank : 38)	θ value	0.62314 (rank : 22)
Query Neighborhood Hits	82	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

ENAH_MOUSE
NC score	0.034330 (rank : 39)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	82	Target Neighborhood Hits	919	Shared Neighborhood Hits	18
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

SFR15_HUMAN
NC score	0.033069 (rank : 40)	θ value	1.81305 (rank : 38)
Query Neighborhood Hits	82	Target Neighborhood Hits	368	Shared Neighborhood Hits	14
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

PI5PA_HUMAN
NC score	0.032861 (rank : 41)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	82	Target Neighborhood Hits	749	Shared Neighborhood Hits	34
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

YLPM1_HUMAN
NC score	0.032763 (rank : 42)	θ value	1.06291 (rank : 30)
Query Neighborhood Hits	82	Target Neighborhood Hits	670	Shared Neighborhood Hits	22
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

RBBP6_MOUSE
NC score	0.031476 (rank : 43)	θ value	1.06291 (rank : 29)
Query Neighborhood Hits	82	Target Neighborhood Hits	1014	Shared Neighborhood Hits	14
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

WASIP_HUMAN
NC score	0.031085 (rank : 44)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	82	Target Neighborhood Hits	458	Shared Neighborhood Hits	18
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

ESPL1_MOUSE
NC score	0.030361 (rank : 45)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	82	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	P60330	Gene names	Espl1, Esp1, Kiaa0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

RBBP6_HUMAN
NC score	0.028873 (rank : 46)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	82	Target Neighborhood Hits	1135	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

FMN2_HUMAN
NC score	0.028794 (rank : 47)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	82	Target Neighborhood Hits	484	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

SF01_MOUSE
NC score	0.028595 (rank : 48)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	82	Target Neighborhood Hits	240	Shared Neighborhood Hits	11
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

CD2_HUMAN
NC score	0.028372 (rank : 49)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	82	Target Neighborhood Hits	504	Shared Neighborhood Hits	32
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CASL_HUMAN
NC score	0.028198 (rank : 50)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	82	Target Neighborhood Hits	259	Shared Neighborhood Hits	10
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

PRB4S_HUMAN
NC score	0.027423 (rank : 51)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	82	Target Neighborhood Hits	330	Shared Neighborhood Hits	10
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

SF3A1_MOUSE
NC score	0.027123 (rank : 52)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	82	Target Neighborhood Hits	198	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

SF3A1_HUMAN
NC score	0.026958 (rank : 53)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	82	Target Neighborhood Hits	199	Shared Neighborhood Hits	7
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

SF01_HUMAN
NC score	0.026434 (rank : 54)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	82	Target Neighborhood Hits	287	Shared Neighborhood Hits	11
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

DAAM1_HUMAN
NC score	0.026053 (rank : 55)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	82	Target Neighborhood Hits	483	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

EFS_HUMAN
NC score	0.025270 (rank : 56)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	82	Target Neighborhood Hits	348	Shared Neighborhood Hits	12
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

RPGF6_HUMAN
NC score	0.025066 (rank : 57)	θ value	1.81305 (rank : 37)
Query Neighborhood Hits	82	Target Neighborhood Hits	266	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

MLL3_HUMAN
NC score	0.025020 (rank : 58)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	82	Target Neighborhood Hits	1644	Shared Neighborhood Hits	41
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

DIAP2_HUMAN
NC score	0.024545 (rank : 59)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	82	Target Neighborhood Hits	342	Shared Neighborhood Hits	16
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

GRLF1_HUMAN
NC score	0.024164 (rank : 60)	θ value	0.163984 (rank : 18)
Query Neighborhood Hits	82	Target Neighborhood Hits	167	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

SIN3B_HUMAN
NC score	0.020966 (rank : 61)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	82	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	O75182, Q68GC2, Q6P4B8, Q8TB34, Q9BSC8	Gene names	SIN3B, KIAA0700
Domain Architecture
Description	Paired amphipathic helix protein Sin3b (Transcriptional corepressor Sin3b) (Histone deacetylase complex subunit Sin3b).

SON_MOUSE
NC score	0.020144 (rank : 62)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	82	Target Neighborhood Hits	957	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

KCNK4_HUMAN
NC score	0.018359 (rank : 63)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	82	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

PLS1_MOUSE
NC score	0.016852 (rank : 64)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	82	Target Neighborhood Hits	58	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JJ00, O54730, O54731, Q9D1F8	Gene names	Plscr1, Tra1b, Tras1
Domain Architecture
Description	Phospholipid scramblase 1 (PL scramblase 1) (Ca(2+)-dependent phospholipid scramblase 1) (Transplantability-associated protein 1) (TRA1) (NOR1).

CRTC1_HUMAN
NC score	0.016186 (rank : 65)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	82	Target Neighborhood Hits	319	Shared Neighborhood Hits	20
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

UBP42_HUMAN
NC score	0.015771 (rank : 66)	θ value	1.38821 (rank : 35)
Query Neighborhood Hits	82	Target Neighborhood Hits	445	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

JPH2_HUMAN
NC score	0.014732 (rank : 67)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	82	Target Neighborhood Hits	639	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

TDPZ1_MOUSE
NC score	0.013864 (rank : 68)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	82	Target Neighborhood Hits	164	Shared Neighborhood Hits	4
SwissProt Accessions	Q717B3, Q71G58, Q8BZV7, Q8VI39	Gene names	Tdpoz1, 2cpoz56, Mapp2, Spopl1
Domain Architecture	No domain graphic available
Description	TD and POZ domain-containing protein 1 (MAPP family protein 2).

ZCHC8_MOUSE
NC score	0.012824 (rank : 69)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	82	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CYA6, Q3TK71, Q8CCB7, Q91WQ1	Gene names	Zcchc8
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 8.

RXRB_HUMAN
NC score	0.012670 (rank : 70)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	82	Target Neighborhood Hits	280	Shared Neighborhood Hits	8
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

RANB9_HUMAN
NC score	0.012100 (rank : 71)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	82	Target Neighborhood Hits	179	Shared Neighborhood Hits	8
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

STAP2_HUMAN
NC score	0.011377 (rank : 72)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	82	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UGK3, Q9NXI2	Gene names	STAP2, BKS
Domain Architecture	No domain graphic available
Description	Signal-transducing adaptor protein 2 (STAP-2) (Breast tumor kinase substrate) (BRK substrate).

SUZ12_HUMAN
NC score	0.011070 (rank : 73)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	82	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q15022, Q96BD9	Gene names	SUZ12, CHET9, JJAZ1, KIAA0160
Domain Architecture	No domain graphic available
Description	Polycomb protein SUZ12 (Suppressor of zeste 12 protein homolog) (Joined to JAZF1 protein) (Chromatin precipitated E2F target 9 protein) (ChET 9 protein).

RXRB_MOUSE
NC score	0.010682 (rank : 74)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	82	Target Neighborhood Hits	230	Shared Neighborhood Hits	9
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

HXA3_MOUSE
NC score	0.009625 (rank : 75)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	82	Target Neighborhood Hits	558	Shared Neighborhood Hits	10
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

LSD1_MOUSE
NC score	0.008269 (rank : 76)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	82	Target Neighborhood Hits	224	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

HXA3_HUMAN
NC score	0.008068 (rank : 77)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	82	Target Neighborhood Hits	535	Shared Neighborhood Hits	11
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

RC3H1_MOUSE
NC score	0.007048 (rank : 78)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	82	Target Neighborhood Hits	244	Shared Neighborhood Hits	4
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

DOCK3_MOUSE
NC score	0.006972 (rank : 79)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	82	Target Neighborhood Hits	93	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CIQ7	Gene names	Dock3, Moca
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

TACC2_MOUSE
NC score	0.006945 (rank : 80)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	82	Target Neighborhood Hits	774	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

CAC1H_MOUSE
NC score	0.006445 (rank : 81)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	82	Target Neighborhood Hits	230	Shared Neighborhood Hits	7
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

ATS19_HUMAN
NC score	0.005652 (rank : 82)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	82	Target Neighborhood Hits	203	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ARX_HUMAN
NC score	0.002760 (rank : 83)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	82	Target Neighborhood Hits	401	Shared Neighborhood Hits	5
SwissProt Accessions	Q96QS3	Gene names	ARX
Domain Architecture
Description	Homeobox protein ARX (Aristaless-related homeobox).

HIC1_MOUSE
NC score	0.000109 (rank : 84)	θ value	2.36792 (rank : 42)
Query Neighborhood Hits	82	Target Neighborhood Hits	863	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

EGFR_HUMAN
NC score	-0.002146 (rank : 85)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	82	Target Neighborhood Hits	939	Shared Neighborhood Hits	2
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).