Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : RXRB_MOUSE

For an explanation of this page, click here

RXRB_MOUSE
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RXRB_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	230	Target Neighborhood Hits	230	Shared Neighborhood Hits	230
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

RXRB_HUMAN
θ value	2.74423e-182 (rank : 2)	NC score	0.994094 (rank : 2)
Query Neighborhood Hits	230	Target Neighborhood Hits	280	Shared Neighborhood Hits	184
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

RXRA_HUMAN
θ value	3.37019e-164 (rank : 3)	NC score	0.989598 (rank : 6)
Query Neighborhood Hits	230	Target Neighborhood Hits	223	Shared Neighborhood Hits	112
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

RXRA_MOUSE
θ value	3.72618e-163 (rank : 4)	NC score	0.992293 (rank : 3)
Query Neighborhood Hits	230	Target Neighborhood Hits	129	Shared Neighborhood Hits	109
SwissProt Accessions	P28700	Gene names	Rxra, Nr2b1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

RXRG_HUMAN
θ value	4.90052e-139 (rank : 5)	NC score	0.991271 (rank : 5)
Query Neighborhood Hits	230	Target Neighborhood Hits	114	Shared Neighborhood Hits	99
SwissProt Accessions	P48443	Gene names	RXRG, NR2B3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

RXRG_MOUSE
θ value	1.09172e-138 (rank : 6)	NC score	0.991542 (rank : 4)
Query Neighborhood Hits	230	Target Neighborhood Hits	113	Shared Neighborhood Hits	100
SwissProt Accessions	P28705	Gene names	Rxrg, Nr2b3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

HNF4G_HUMAN
θ value	4.09345e-69 (rank : 7)	NC score	0.978300 (rank : 8)
Query Neighborhood Hits	230	Target Neighborhood Hits	100	Shared Neighborhood Hits	98
SwissProt Accessions	Q14541, Q9UH81, Q9UIS6	Gene names	HNF4G, NR2A2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

COT1_HUMAN
θ value	5.34618e-69 (rank : 8)	NC score	0.974797 (rank : 16)
Query Neighborhood Hits	230	Target Neighborhood Hits	159	Shared Neighborhood Hits	105
SwissProt Accessions	P10589	Gene names	NR2F1, EAR3, ERBAL3, TFCOUP1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I) (V-ERBA-related protein EAR-3).

COT1_MOUSE
θ value	5.34618e-69 (rank : 9)	NC score	0.974917 (rank : 15)
Query Neighborhood Hits	230	Target Neighborhood Hits	160	Shared Neighborhood Hits	103
SwissProt Accessions	Q60632, Q61438	Gene names	Nr2f1, Erbal3, Tfcoup1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I).

COT2_HUMAN
θ value	6.98233e-69 (rank : 10)	NC score	0.975931 (rank : 12)
Query Neighborhood Hits	230	Target Neighborhood Hits	135	Shared Neighborhood Hits	102
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT2_MOUSE
θ value	6.98233e-69 (rank : 11)	NC score	0.975931 (rank : 13)
Query Neighborhood Hits	230	Target Neighborhood Hits	135	Shared Neighborhood Hits	102
SwissProt Accessions	P43135	Gene names	Nr2f2, Aporp1, Arp-1, Arp1, Tfcoup2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

HNF4A_HUMAN
θ value	1.71981e-67 (rank : 12)	NC score	0.977544 (rank : 10)
Query Neighborhood Hits	230	Target Neighborhood Hits	105	Shared Neighborhood Hits	98
SwissProt Accessions	P41235, O00659, O00723, Q14540, Q92653, Q92654, Q92655, Q99864, Q9NQH0	Gene names	HNF4A, HNF4, NR2A1, TCF14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

HNF4A_MOUSE
θ value	2.4834e-66 (rank : 13)	NC score	0.977565 (rank : 9)
Query Neighborhood Hits	230	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	P49698	Gene names	Hnf4a, Hnf-4, Hnf4, Nr2a1, Tcf14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

HNF4G_MOUSE
θ value	4.23606e-66 (rank : 14)	NC score	0.978504 (rank : 7)
Query Neighborhood Hits	230	Target Neighborhood Hits	101	Shared Neighborhood Hits	98
SwissProt Accessions	Q9WUU6	Gene names	Hnf4g, Nr2a2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

EAR2_MOUSE
θ value	3.84025e-59 (rank : 15)	NC score	0.975136 (rank : 14)
Query Neighborhood Hits	230	Target Neighborhood Hits	104	Shared Neighborhood Hits	99
SwissProt Accessions	P43136, Q61504	Gene names	Nr2f6, Ear-2, Ear2, Erbal2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

EAR2_HUMAN
θ value	8.55514e-59 (rank : 16)	NC score	0.976327 (rank : 11)
Query Neighborhood Hits	230	Target Neighborhood Hits	106	Shared Neighborhood Hits	99
SwissProt Accessions	P10588, Q9BUE8	Gene names	NR2F6, EAR2, ERBAL2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

NR2E3_HUMAN
θ value	2.84797e-54 (rank : 17)	NC score	0.972607 (rank : 17)
Query Neighborhood Hits	230	Target Neighborhood Hits	102	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Y5X4, Q9UHM4	Gene names	NR2E3, PNR, RNR
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

ERR3_HUMAN
θ value	8.28633e-54 (rank : 18)	NC score	0.959968 (rank : 21)
Query Neighborhood Hits	230	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P62508, O75454, O96021, Q68DA0, Q6P274, Q6PK28, Q6TS38, Q9R1F3, Q9UNJ4	Gene names	ESRRG, ERR3, ERRG2, KIAA0832, NR3B3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (ERR gamma-2).

ERR3_MOUSE
θ value	8.28633e-54 (rank : 19)	NC score	0.959968 (rank : 22)
Query Neighborhood Hits	230	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P62509, O75454, O96021, Q8CHC9, Q9R1F3	Gene names	Esrrg, Err3, Kiaa0832, Nr3b3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3).

ERR2_MOUSE
θ value	3.48141e-52 (rank : 20)	NC score	0.959500 (rank : 23)
Query Neighborhood Hits	230	Target Neighborhood Hits	109	Shared Neighborhood Hits	98
SwissProt Accessions	Q61539, O09067, O09146	Gene names	Esrrb, Err-2, Err2, Nr3b2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2).

NR2E3_MOUSE
θ value	7.75577e-52 (rank : 21)	NC score	0.970879 (rank : 18)
Query Neighborhood Hits	230	Target Neighborhood Hits	113	Shared Neighborhood Hits	98
SwissProt Accessions	Q9QXZ7	Gene names	Nr2e3, Pnr, Rnr
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

ERR2_HUMAN
θ value	1.91031e-50 (rank : 22)	NC score	0.957240 (rank : 24)
Query Neighborhood Hits	230	Target Neighborhood Hits	108	Shared Neighborhood Hits	99
SwissProt Accessions	O95718, Q9HCB4	Gene names	ESRRB, ERRB2, NR3B2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2) (ERR beta-2).

NR2E1_MOUSE
θ value	4.25575e-50 (rank : 23)	NC score	0.969625 (rank : 19)
Query Neighborhood Hits	230	Target Neighborhood Hits	106	Shared Neighborhood Hits	99
SwissProt Accessions	Q64104	Gene names	Nr2e1, Tll, Tlx
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (mTll).

RARB_HUMAN
θ value	1.23823e-49 (rank : 24)	NC score	0.944729 (rank : 26)
Query Neighborhood Hits	230	Target Neighborhood Hits	118	Shared Neighborhood Hits	94
SwissProt Accessions	P10826, P12891, Q00989, Q15298, Q9UN48	Gene names	RARB, HAP, NR1B2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta) (RAR-epsilon) (HBV-activated protein).

RARB_MOUSE
θ value	1.23823e-49 (rank : 25)	NC score	0.944645 (rank : 27)
Query Neighborhood Hits	230	Target Neighborhood Hits	109	Shared Neighborhood Hits	95
SwissProt Accessions	P22605, P11417, P22604	Gene names	Rarb, Nr1b2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta).

RARA_MOUSE
θ value	1.788e-48 (rank : 26)	NC score	0.944362 (rank : 28)
Query Neighborhood Hits	230	Target Neighborhood Hits	113	Shared Neighborhood Hits	98
SwissProt Accessions	P11416, P22603	Gene names	Rara, Nr1b1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARA_HUMAN
θ value	2.3352e-48 (rank : 27)	NC score	0.944172 (rank : 29)
Query Neighborhood Hits	230	Target Neighborhood Hits	118	Shared Neighborhood Hits	97
SwissProt Accessions	P10276, P78456, Q13440, Q13441, Q9NQS0	Gene names	RARA, NR1B1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARG1_MOUSE
θ value	1.28137e-46 (rank : 28)	NC score	0.943338 (rank : 33)
Query Neighborhood Hits	230	Target Neighborhood Hits	113	Shared Neighborhood Hits	96
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

RARG2_MOUSE
θ value	1.28137e-46 (rank : 29)	NC score	0.943610 (rank : 32)
Query Neighborhood Hits	230	Target Neighborhood Hits	114	Shared Neighborhood Hits	96
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

RARG1_HUMAN
θ value	8.30557e-46 (rank : 30)	NC score	0.943706 (rank : 31)
Query Neighborhood Hits	230	Target Neighborhood Hits	107	Shared Neighborhood Hits	95
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARG2_HUMAN
θ value	8.30557e-46 (rank : 31)	NC score	0.943843 (rank : 30)
Query Neighborhood Hits	230	Target Neighborhood Hits	109	Shared Neighborhood Hits	95
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

NR4A2_HUMAN
θ value	2.95404e-43 (rank : 32)	NC score	0.943120 (rank : 36)
Query Neighborhood Hits	230	Target Neighborhood Hits	120	Shared Neighborhood Hits	99
SwissProt Accessions	P43354, Q16311	Gene names	NR4A2, NOT, NURR1, TINUR
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (Immediate-early response protein NOT) (Transcriptionally-inducible nuclear receptor).

NR4A2_MOUSE
θ value	2.95404e-43 (rank : 33)	NC score	0.943175 (rank : 35)
Query Neighborhood Hits	230	Target Neighborhood Hits	121	Shared Neighborhood Hits	99
SwissProt Accessions	Q06219, O08690	Gene names	Nr4a2, Nurr1
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (NUR- related factor 1).

NR2E1_HUMAN
θ value	1.46607e-42 (rank : 34)	NC score	0.967348 (rank : 20)
Query Neighborhood Hits	230	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y466	Gene names	NR2E1, TLX
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (hTll).

ESR2_HUMAN
θ value	6.15952e-41 (rank : 35)	NC score	0.940507 (rank : 38)
Query Neighborhood Hits	230	Target Neighborhood Hits	110	Shared Neighborhood Hits	97
SwissProt Accessions	Q92731, O60608, O60685, O60702, O60703, O75583, O75584, Q86Z31, Q9UEV6, Q9UHD3, Q9UQK9	Gene names	ESR2, ESTRB, NR3A2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

ERR1_HUMAN
θ value	2.58786e-39 (rank : 36)	NC score	0.955297 (rank : 25)
Query Neighborhood Hits	230	Target Neighborhood Hits	157	Shared Neighborhood Hits	101
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

NR4A3_MOUSE
θ value	2.58786e-39 (rank : 37)	NC score	0.943178 (rank : 34)
Query Neighborhood Hits	230	Target Neighborhood Hits	127	Shared Neighborhood Hits	103
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

NR4A3_HUMAN
θ value	4.88048e-38 (rank : 38)	NC score	0.942427 (rank : 37)
Query Neighborhood Hits	230	Target Neighborhood Hits	131	Shared Neighborhood Hits	102
SwissProt Accessions	Q92570, Q12935, Q14979, Q16420, Q4VXA9, Q9UEK2, Q9UEK3	Gene names	NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1) (Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphan receptor).

ESR2_MOUSE
θ value	1.32909e-35 (rank : 39)	NC score	0.938670 (rank : 40)
Query Neighborhood Hits	230	Target Neighborhood Hits	110	Shared Neighborhood Hits	96
SwissProt Accessions	O08537, O35635, O70519	Gene names	Esr2, Estrb, Nr3a2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

ESR1_HUMAN
θ value	1.46948e-34 (rank : 40)	NC score	0.934228 (rank : 42)
Query Neighborhood Hits	230	Target Neighborhood Hits	105	Shared Neighborhood Hits	97
SwissProt Accessions	P03372, Q13511, Q14276, Q9NU51, Q9UDZ7, Q9UIS7	Gene names	ESR1, ESR, NR3A1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

THA_HUMAN
θ value	1.24399e-33 (rank : 41)	NC score	0.923495 (rank : 54)
Query Neighborhood Hits	230	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	P10827, P21205, Q8N6A1, Q96H73	Gene names	THRA, ERBA1, NR1A1, THRA1
Domain Architecture
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1) (EAR-7) (EAR7).

NR4A1_HUMAN
θ value	1.6247e-33 (rank : 42)	NC score	0.939476 (rank : 39)
Query Neighborhood Hits	230	Target Neighborhood Hits	133	Shared Neighborhood Hits	103
SwissProt Accessions	P22736	Gene names	NR4A1, GFRP1, HMR, NAK1
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Early response protein NAK1) (TR3 orphan receptor) (ST-59).

THA_MOUSE
θ value	1.6247e-33 (rank : 43)	NC score	0.923432 (rank : 55)
Query Neighborhood Hits	230	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	P63058, P10685, P15827, P16416, P37241, Q63107, Q63195, Q63196, Q99146	Gene names	Thra, C-erba-alpha, Nr1a1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1).

PPARA_HUMAN
θ value	4.72714e-33 (rank : 44)	NC score	0.916413 (rank : 64)
Query Neighborhood Hits	230	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q07869, Q16241, Q92486, Q92689, Q9Y3N1	Gene names	PPARA, NR1C1, PPAR
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

ESR1_MOUSE
θ value	1.0531e-32 (rank : 45)	NC score	0.934091 (rank : 43)
Query Neighborhood Hits	230	Target Neighborhood Hits	104	Shared Neighborhood Hits	96
SwissProt Accessions	P19785, Q9JJT5, Q9QY51, Q9QY52	Gene names	Esr1, Esr, Estr, Estra, Nr3a1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

THB2_HUMAN
θ value	3.06405e-32 (rank : 46)	NC score	0.917540 (rank : 62)
Query Neighborhood Hits	230	Target Neighborhood Hits	104	Shared Neighborhood Hits	100
SwissProt Accessions	P37243	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor beta-2.

THB1_HUMAN
θ value	6.82597e-32 (rank : 47)	NC score	0.917107 (rank : 63)
Query Neighborhood Hits	230	Target Neighborhood Hits	106	Shared Neighborhood Hits	100
SwissProt Accessions	P10828, Q13986	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture
Description	Thyroid hormone receptor beta-1.

THB1_MOUSE
θ value	1.52067e-31 (rank : 48)	NC score	0.915944 (rank : 65)
Query Neighborhood Hits	230	Target Neighborhood Hits	105	Shared Neighborhood Hits	98
SwissProt Accessions	P37242	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-1.

THB2_MOUSE
θ value	1.52067e-31 (rank : 49)	NC score	0.915928 (rank : 66)
Query Neighborhood Hits	230	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P37244	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-2.

NR1H3_HUMAN
θ value	4.42448e-31 (rank : 50)	NC score	0.926175 (rank : 50)
Query Neighborhood Hits	230	Target Neighborhood Hits	104	Shared Neighborhood Hits	95
SwissProt Accessions	Q13133, Q96H87	Gene names	NR1H3, LXRA
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

NR1H3_MOUSE
θ value	1.6813e-30 (rank : 51)	NC score	0.925361 (rank : 53)
Query Neighborhood Hits	230	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Z0Y9, Q9QUH7	Gene names	Nr1h3, Lxra
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

PPARA_MOUSE
θ value	2.19584e-30 (rank : 52)	NC score	0.915217 (rank : 67)
Query Neighborhood Hits	230	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	P23204	Gene names	Ppara, Nr1c1, Ppar
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

NR4A1_MOUSE
θ value	2.86786e-30 (rank : 53)	NC score	0.937113 (rank : 41)
Query Neighborhood Hits	230	Target Neighborhood Hits	128	Shared Neighborhood Hits	95
SwissProt Accessions	P12813	Gene names	Nr4a1, Gfrp, Hmr, N10, Nur77
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Nuclear hormone receptor NUR/77) (N10 nuclear protein).

TR2_MOUSE
θ value	4.89182e-30 (rank : 54)	NC score	0.926242 (rank : 48)
Query Neighborhood Hits	230	Target Neighborhood Hits	100	Shared Neighborhood Hits	98
SwissProt Accessions	Q505F1, P97763, Q3UIJ7, Q4U1Z4, Q60927, Q62152, Q8VIJ3	Gene names	Nr2c1, Tr2, Tr2-11
Domain Architecture	No domain graphic available
Description	Orphan nuclear receptor TR2 (Testicular receptor 2) (mTR2).

NR5A2_HUMAN
θ value	1.08979e-29 (rank : 55)	NC score	0.921250 (rank : 58)
Query Neighborhood Hits	230	Target Neighborhood Hits	112	Shared Neighborhood Hits	99
SwissProt Accessions	O00482, O95642	Gene names	NR5A2, B1F, CPF, FTF
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Alpha-1-fetoprotein transcription factor) (Hepatocytic transcription factor) (B1-binding factor) (hB1F) (CYP7A promoter-binding factor) (Liver receptor homolog 1) (LRH-1).

TR2_HUMAN
θ value	1.08979e-29 (rank : 56)	NC score	0.928996 (rank : 44)
Query Neighborhood Hits	230	Target Neighborhood Hits	110	Shared Neighborhood Hits	97
SwissProt Accessions	P13056	Gene names	NR2C1, TR2
Domain Architecture
Description	Orphan nuclear receptor TR2 (Testicular receptor 2).

NR1H4_MOUSE
θ value	2.42779e-29 (rank : 57)	NC score	0.926234 (rank : 49)
Query Neighborhood Hits	230	Target Neighborhood Hits	113	Shared Neighborhood Hits	98
SwissProt Accessions	Q60641, Q60642, Q60643	Gene names	Nr1h4, Bar, Fxr, Rip14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

TR4_HUMAN
θ value	5.40856e-29 (rank : 58)	NC score	0.926023 (rank : 51)
Query Neighborhood Hits	230	Target Neighborhood Hits	117	Shared Neighborhood Hits	99
SwissProt Accessions	P49116, P55092	Gene names	NR2C2, TAK1, TR4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

NR1H4_HUMAN
θ value	1.2049e-28 (rank : 59)	NC score	0.926758 (rank : 47)
Query Neighborhood Hits	230	Target Neighborhood Hits	112	Shared Neighborhood Hits	98
SwissProt Accessions	Q96RI1, Q8NFP5, Q8NFP6, Q92943	Gene names	NR1H4, BAR, FXR, HRR1, RIP14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

NR5A2_MOUSE
θ value	1.2049e-28 (rank : 60)	NC score	0.922989 (rank : 57)
Query Neighborhood Hits	230	Target Neighborhood Hits	107	Shared Neighborhood Hits	98
SwissProt Accessions	P45448	Gene names	Nr5a2, Lrh1
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Liver receptor homolog 1) (LRH-1).

TR4_MOUSE
θ value	2.05525e-28 (rank : 61)	NC score	0.925364 (rank : 52)
Query Neighborhood Hits	230	Target Neighborhood Hits	115	Shared Neighborhood Hits	99
SwissProt Accessions	P49117, P55093	Gene names	Nr2c2, Mtr2r1, Tak1, Tr4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

ANDR_MOUSE
θ value	1.92365e-26 (rank : 62)	NC score	0.883179 (rank : 87)
Query Neighborhood Hits	230	Target Neighborhood Hits	133	Shared Neighborhood Hits	102
SwissProt Accessions	P19091	Gene names	Ar, Nr3c4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

NR1H2_MOUSE
θ value	2.12685e-25 (rank : 63)	NC score	0.913589 (rank : 68)
Query Neighborhood Hits	230	Target Neighborhood Hits	109	Shared Neighborhood Hits	98
SwissProt Accessions	Q60644	Gene names	Nr1h2, Lxrb, Rip15, Unr, Unr2
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Retinoid X receptor-interacting protein No.15).

RORA_HUMAN
θ value	4.73814e-25 (rank : 64)	NC score	0.899205 (rank : 83)
Query Neighborhood Hits	230	Target Neighborhood Hits	105	Shared Neighborhood Hits	95
SwissProt Accessions	P35398, P35397, P35399, P45445, Q96H83	Gene names	RORA, NR1F1, RZRA
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

RORA_MOUSE
θ value	4.73814e-25 (rank : 65)	NC score	0.898575 (rank : 85)
Query Neighborhood Hits	230	Target Neighborhood Hits	105	Shared Neighborhood Hits	95
SwissProt Accessions	P51448, P70283, P97741, P97773, Q923G1	Gene names	Rora, Nr1f1, Rzra
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

PXR_HUMAN
θ value	1.05554e-24 (rank : 66)	NC score	0.899256 (rank : 81)
Query Neighborhood Hits	230	Target Neighborhood Hits	107	Shared Neighborhood Hits	97
SwissProt Accessions	O75469, Q96AC7, Q9UJ22, Q9UJ23, Q9UJ24, Q9UJ25, Q9UJ26, Q9UJ27	Gene names	NR1I2, PXR
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor) (Orphan nuclear receptor PAR1) (Steroid and xenobiotic receptor) (SXR).

NR6A1_MOUSE
θ value	1.80048e-24 (rank : 67)	NC score	0.928059 (rank : 46)
Query Neighborhood Hits	230	Target Neighborhood Hits	110	Shared Neighborhood Hits	98
SwissProt Accessions	Q64249	Gene names	Nr6a1, Gcnf
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

STF1_HUMAN
θ value	2.35151e-24 (rank : 68)	NC score	0.918745 (rank : 60)
Query Neighborhood Hits	230	Target Neighborhood Hits	132	Shared Neighborhood Hits	107
SwissProt Accessions	Q13285, O15196	Gene names	NR5A1, AD4BP, FTZF1, SF1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1).

STF1_MOUSE
θ value	2.35151e-24 (rank : 69)	NC score	0.921232 (rank : 59)
Query Neighborhood Hits	230	Target Neighborhood Hits	137	Shared Neighborhood Hits	111
SwissProt Accessions	P33242	Gene names	Nr5a1, Ftzf1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1) (Embryonal LTR-binding protein) (ELP) (Embryonal long terminal repeat- binding protein) (Steroid hydroxylase positive regulator).

NR6A1_HUMAN
θ value	4.01107e-24 (rank : 70)	NC score	0.928670 (rank : 45)
Query Neighborhood Hits	230	Target Neighborhood Hits	108	Shared Neighborhood Hits	98
SwissProt Accessions	Q15406, O00551, O00603, Q8NHQ0, Q92898, Q99802	Gene names	NR6A1, GCNF
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

RORB_HUMAN
θ value	4.01107e-24 (rank : 71)	NC score	0.899200 (rank : 84)
Query Neighborhood Hits	230	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	Q92753, Q8WX73	Gene names	RORB, NR1F2, RZRB
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORB_MOUSE
θ value	4.01107e-24 (rank : 72)	NC score	0.899205 (rank : 82)
Query Neighborhood Hits	230	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	Q8R1B8	Gene names	Rorb, Nr1f2
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORG_HUMAN
θ value	4.01107e-24 (rank : 73)	NC score	0.897901 (rank : 86)
Query Neighborhood Hits	230	Target Neighborhood Hits	119	Shared Neighborhood Hits	96
SwissProt Accessions	P51449, Q8N5V7, Q8NCY8	Gene names	RORC, NR1F3, RORG, RZRG
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma).

ANDR_HUMAN
θ value	6.84181e-24 (rank : 74)	NC score	0.880271 (rank : 89)
Query Neighborhood Hits	230	Target Neighborhood Hits	126	Shared Neighborhood Hits	99
SwissProt Accessions	P10275	Gene names	AR, DHTR, NR3C4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

RORG_MOUSE
θ value	6.84181e-24 (rank : 75)	NC score	0.901104 (rank : 77)
Query Neighborhood Hits	230	Target Neighborhood Hits	107	Shared Neighborhood Hits	95
SwissProt Accessions	P51450, Q61027, Q91YT5, Q9QXD9, Q9R177	Gene names	Rorc, Nr1f3, Rorg, Thor
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma) (Thymus orphan receptor) (TOR).

GCR_HUMAN
θ value	1.16704e-23 (rank : 76)	NC score	0.883131 (rank : 88)
Query Neighborhood Hits	230	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P04150, P04151, Q53EP5, Q6N0A4	Gene names	NR3C1, GRL
Domain Architecture
Description	Glucocorticoid receptor (GR).

MCR_HUMAN
θ value	1.5242e-23 (rank : 77)	NC score	0.876857 (rank : 91)
Query Neighborhood Hits	230	Target Neighborhood Hits	149	Shared Neighborhood Hits	104
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

GCR_MOUSE
θ value	1.29031e-22 (rank : 78)	NC score	0.877422 (rank : 90)
Query Neighborhood Hits	230	Target Neighborhood Hits	117	Shared Neighborhood Hits	96
SwissProt Accessions	P06537, Q61628, Q61629	Gene names	Nr3c1, Grl, Grl1
Domain Architecture
Description	Glucocorticoid receptor (GR).

PPARG_HUMAN
θ value	3.75424e-22 (rank : 79)	NC score	0.908830 (rank : 72)
Query Neighborhood Hits	230	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37231, O00684, O00710, O14515, Q15178, Q15179, Q15180, Q15832, Q86U60, Q96J12	Gene names	PPARG, NR1C3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

PPARG_MOUSE
θ value	3.75424e-22 (rank : 80)	NC score	0.908435 (rank : 73)
Query Neighborhood Hits	230	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37238	Gene names	Pparg, Nr1c3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

PPARD_HUMAN
θ value	6.40375e-22 (rank : 81)	NC score	0.910977 (rank : 70)
Query Neighborhood Hits	230	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q03181, Q7Z5K0, Q9BUD4	Gene names	PPARD, NR1C2, PPARB
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1) (NUCI).

PPARD_MOUSE
θ value	1.09232e-21 (rank : 82)	NC score	0.908833 (rank : 71)
Query Neighborhood Hits	230	Target Neighborhood Hits	103	Shared Neighborhood Hits	95
SwissProt Accessions	P35396, P37239	Gene names	Ppard, Nr1c2, Pparb
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1).

NR1D2_HUMAN
θ value	1.86321e-21 (rank : 83)	NC score	0.904322 (rank : 75)
Query Neighborhood Hits	230	Target Neighborhood Hits	115	Shared Neighborhood Hits	94
SwissProt Accessions	Q14995, O00402, Q86XD4	Gene names	NR1D2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (EAR-1R) (Orphan nuclear hormone receptor BD73).

NR1D2_MOUSE
θ value	1.86321e-21 (rank : 84)	NC score	0.901895 (rank : 76)
Query Neighborhood Hits	230	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	Q60674, Q60646	Gene names	Nr1d2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (Orphan nuclear receptor RVR).

NR1D1_HUMAN
θ value	3.17815e-21 (rank : 85)	NC score	0.911964 (rank : 69)
Query Neighborhood Hits	230	Target Neighborhood Hits	140	Shared Neighborhood Hits	103
SwissProt Accessions	P20393, Q15304	Gene names	NR1D1, EAR1, HREV, THRAL
Domain Architecture
Description	Orphan nuclear receptor NR1D1 (V-erbA-related protein EAR-1) (Rev- erbA-alpha).

PRGR_MOUSE
θ value	4.15078e-21 (rank : 86)	NC score	0.867586 (rank : 94)
Query Neighborhood Hits	230	Target Neighborhood Hits	286	Shared Neighborhood Hits	115
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

MCR_MOUSE
θ value	1.5773e-20 (rank : 87)	NC score	0.872182 (rank : 92)
Query Neighborhood Hits	230	Target Neighborhood Hits	162	Shared Neighborhood Hits	104
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

NR1I3_HUMAN
θ value	3.88503e-19 (rank : 88)	NC score	0.923285 (rank : 56)
Query Neighborhood Hits	230	Target Neighborhood Hits	107	Shared Neighborhood Hits	99
SwissProt Accessions	Q14994	Gene names	NR1I3, CAR
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Constitutive activator of retinoid response) (Constitutive active response) (Orphan nuclear receptor MB67).

VDR_HUMAN
θ value	1.63225e-17 (rank : 89)	NC score	0.900837 (rank : 79)
Query Neighborhood Hits	230	Target Neighborhood Hits	112	Shared Neighborhood Hits	96
SwissProt Accessions	P11473	Gene names	VDR, NR1I1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

VDR_MOUSE
θ value	6.20254e-17 (rank : 90)	NC score	0.899738 (rank : 80)
Query Neighborhood Hits	230	Target Neighborhood Hits	103	Shared Neighborhood Hits	96
SwissProt Accessions	P48281	Gene names	Vdr, Nr1i1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

PXR_MOUSE
θ value	1.058e-16 (rank : 91)	NC score	0.901025 (rank : 78)
Query Neighborhood Hits	230	Target Neighborhood Hits	107	Shared Neighborhood Hits	97
SwissProt Accessions	O54915	Gene names	Nr1i2, Pxr
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor).

NR1I3_MOUSE
θ value	1.80466e-16 (rank : 92)	NC score	0.917741 (rank : 61)
Query Neighborhood Hits	230	Target Neighborhood Hits	103	Shared Neighborhood Hits	100
SwissProt Accessions	O35627, O35628	Gene names	Nr1i3, Car
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67).

NR1H2_HUMAN
θ value	4.02038e-16 (rank : 93)	NC score	0.907006 (rank : 74)
Query Neighborhood Hits	230	Target Neighborhood Hits	114	Shared Neighborhood Hits	100
SwissProt Accessions	P55055, Q12970	Gene names	NR1H2, LXRB, NER, UNR
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Nuclear receptor NER).

PRGR_HUMAN
θ value	8.95645e-16 (rank : 94)	NC score	0.871935 (rank : 93)
Query Neighborhood Hits	230	Target Neighborhood Hits	163	Shared Neighborhood Hits	106
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

SHP_HUMAN
θ value	3.89403e-11 (rank : 95)	NC score	0.603222 (rank : 95)
Query Neighborhood Hits	230	Target Neighborhood Hits	57	Shared Neighborhood Hits	56
SwissProt Accessions	Q15466, Q5QP36	Gene names	NR0B2, SHP
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

DAX1_MOUSE
θ value	1.133e-10 (rank : 96)	NC score	0.584387 (rank : 97)
Query Neighborhood Hits	230	Target Neighborhood Hits	70	Shared Neighborhood Hits	60
SwissProt Accessions	Q61066, O09068, O09147	Gene names	Nr0b1, Ahch, Dax1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1).

SHP_MOUSE
θ value	1.9326e-10 (rank : 97)	NC score	0.594275 (rank : 96)
Query Neighborhood Hits	230	Target Neighborhood Hits	53	Shared Neighborhood Hits	53
SwissProt Accessions	Q62227, Q53Z53	Gene names	Nr0b2, Shp
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

DAX1_HUMAN
θ value	2.52405e-10 (rank : 98)	NC score	0.561957 (rank : 98)
Query Neighborhood Hits	230	Target Neighborhood Hits	65	Shared Neighborhood Hits	59
SwissProt Accessions	P51843, Q96F69	Gene names	NR0B1, AHC, DAX1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1) (DSS-AHC critical region on the X chromosome protein 1).

RGS3_MOUSE
θ value	0.000270298 (rank : 99)	NC score	0.030891 (rank : 108)
Query Neighborhood Hits	230	Target Neighborhood Hits	1621	Shared Neighborhood Hits	76
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SON_HUMAN
θ value	0.00102713 (rank : 100)	NC score	0.029466 (rank : 111)
Query Neighborhood Hits	230	Target Neighborhood Hits	1568	Shared Neighborhood Hits	82
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

RGS3_HUMAN
θ value	0.00390308 (rank : 101)	NC score	0.022038 (rank : 127)
Query Neighborhood Hits	230	Target Neighborhood Hits	1375	Shared Neighborhood Hits	59
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

CECR2_HUMAN
θ value	0.0113563 (rank : 102)	NC score	0.021968 (rank : 128)
Query Neighborhood Hits	230	Target Neighborhood Hits	543	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

NCOA6_HUMAN
θ value	0.0113563 (rank : 103)	NC score	0.044415 (rank : 101)
Query Neighborhood Hits	230	Target Neighborhood Hits	1202	Shared Neighborhood Hits	86
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

CO9A1_MOUSE
θ value	0.0148317 (rank : 104)	NC score	0.018709 (rank : 140)
Query Neighborhood Hits	230	Target Neighborhood Hits	477	Shared Neighborhood Hits	48
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

NCOA6_MOUSE
θ value	0.0252991 (rank : 105)	NC score	0.045865 (rank : 100)
Query Neighborhood Hits	230	Target Neighborhood Hits	1076	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NRX2A_HUMAN
θ value	0.0252991 (rank : 106)	NC score	0.016659 (rank : 146)
Query Neighborhood Hits	230	Target Neighborhood Hits	614	Shared Neighborhood Hits	35
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	0.0252991 (rank : 107)	NC score	0.025253 (rank : 121)
Query Neighborhood Hits	230	Target Neighborhood Hits	481	Shared Neighborhood Hits	33
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

CEL_HUMAN
θ value	0.0330416 (rank : 108)	NC score	0.021113 (rank : 129)
Query Neighborhood Hits	230	Target Neighborhood Hits	896	Shared Neighborhood Hits	51
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

MLL3_HUMAN
θ value	0.0563607 (rank : 109)	NC score	0.026238 (rank : 118)
Query Neighborhood Hits	230	Target Neighborhood Hits	1644	Shared Neighborhood Hits	87
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

NACAM_MOUSE
θ value	0.0736092 (rank : 110)	NC score	0.029239 (rank : 112)
Query Neighborhood Hits	230	Target Neighborhood Hits	1866	Shared Neighborhood Hits	89
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

MAGE1_HUMAN
θ value	0.0961366 (rank : 111)	NC score	0.026176 (rank : 119)
Query Neighborhood Hits	230	Target Neighborhood Hits	1389	Shared Neighborhood Hits	81
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

OGFR_HUMAN
θ value	0.0961366 (rank : 112)	NC score	0.027750 (rank : 113)
Query Neighborhood Hits	230	Target Neighborhood Hits	1582	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PRRT3_HUMAN
θ value	0.125558 (rank : 113)	NC score	0.027085 (rank : 116)
Query Neighborhood Hits	230	Target Neighborhood Hits	998	Shared Neighborhood Hits	63
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SPT5H_HUMAN
θ value	0.163984 (rank : 114)	NC score	0.027576 (rank : 114)
Query Neighborhood Hits	230	Target Neighborhood Hits	436	Shared Neighborhood Hits	45
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	0.163984 (rank : 115)	NC score	0.027537 (rank : 115)
Query Neighborhood Hits	230	Target Neighborhood Hits	437	Shared Neighborhood Hits	45
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

TCGAP_HUMAN
θ value	0.163984 (rank : 116)	NC score	0.020317 (rank : 131)
Query Neighborhood Hits	230	Target Neighborhood Hits	872	Shared Neighborhood Hits	68
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

BCL9_MOUSE
θ value	0.21417 (rank : 117)	NC score	0.053802 (rank : 99)
Query Neighborhood Hits	230	Target Neighborhood Hits	770	Shared Neighborhood Hits	82
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

MILK1_MOUSE
θ value	0.279714 (rank : 118)	NC score	0.019840 (rank : 134)
Query Neighborhood Hits	230	Target Neighborhood Hits	788	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

ZN687_HUMAN
θ value	0.279714 (rank : 119)	NC score	0.002399 (rank : 209)
Query Neighborhood Hits	230	Target Neighborhood Hits	1244	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

BAT2_HUMAN
θ value	0.365318 (rank : 120)	NC score	0.038000 (rank : 103)
Query Neighborhood Hits	230	Target Neighborhood Hits	931	Shared Neighborhood Hits	83
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT2_MOUSE
θ value	0.365318 (rank : 121)	NC score	0.035359 (rank : 106)
Query Neighborhood Hits	230	Target Neighborhood Hits	947	Shared Neighborhood Hits	79
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BCL9_HUMAN
θ value	0.47712 (rank : 122)	NC score	0.044003 (rank : 102)
Query Neighborhood Hits	230	Target Neighborhood Hits	1008	Shared Neighborhood Hits	84
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

F120C_HUMAN
θ value	0.47712 (rank : 123)	NC score	0.018462 (rank : 142)
Query Neighborhood Hits	230	Target Neighborhood Hits	91	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NX05	Gene names	FAM120C, CXorf17
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120C (Tumor antigen BJ-HCC-21).

MAST4_HUMAN
θ value	0.47712 (rank : 124)	NC score	-0.005421 (rank : 224)
Query Neighborhood Hits	230	Target Neighborhood Hits	1804	Shared Neighborhood Hits	53
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

CBP_MOUSE
θ value	0.62314 (rank : 125)	NC score	0.032394 (rank : 107)
Query Neighborhood Hits	230	Target Neighborhood Hits	1051	Shared Neighborhood Hits	79
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DOK2_MOUSE
θ value	0.62314 (rank : 126)	NC score	0.018690 (rank : 141)
Query Neighborhood Hits	230	Target Neighborhood Hits	244	Shared Neighborhood Hits	20
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

FREA_HUMAN
θ value	0.62314 (rank : 127)	NC score	0.005318 (rank : 199)
Query Neighborhood Hits	230	Target Neighborhood Hits	205	Shared Neighborhood Hits	17
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

IASPP_MOUSE
θ value	0.62314 (rank : 128)	NC score	0.007957 (rank : 189)
Query Neighborhood Hits	230	Target Neighborhood Hits	1024	Shared Neighborhood Hits	53
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

MAP1A_HUMAN
θ value	0.62314 (rank : 129)	NC score	0.008718 (rank : 185)
Query Neighborhood Hits	230	Target Neighborhood Hits	1626	Shared Neighborhood Hits	58
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MISS_MOUSE
θ value	0.62314 (rank : 130)	NC score	0.035442 (rank : 105)
Query Neighborhood Hits	230	Target Neighborhood Hits	444	Shared Neighborhood Hits	51
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

PAX7_HUMAN
θ value	0.62314 (rank : 131)	NC score	0.002288 (rank : 210)
Query Neighborhood Hits	230	Target Neighborhood Hits	456	Shared Neighborhood Hits	11
SwissProt Accessions	P23759	Gene names	PAX7, HUP1
Domain Architecture
Description	Paired box protein Pax-7 (HUP1).

PCLO_MOUSE
θ value	0.62314 (rank : 132)	NC score	0.016918 (rank : 145)
Query Neighborhood Hits	230	Target Neighborhood Hits	2275	Shared Neighborhood Hits	93
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RBNS5_MOUSE
θ value	0.62314 (rank : 133)	NC score	0.010500 (rank : 171)
Query Neighborhood Hits	230	Target Neighborhood Hits	266	Shared Neighborhood Hits	13
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

F120C_MOUSE
θ value	0.813845 (rank : 134)	NC score	0.018036 (rank : 143)
Query Neighborhood Hits	230	Target Neighborhood Hits	98	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C3F2	Gene names	Fam120c, ORF34
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120C.

MYO15_HUMAN
θ value	0.813845 (rank : 135)	NC score	0.009085 (rank : 181)
Query Neighborhood Hits	230	Target Neighborhood Hits	671	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NCOR1_HUMAN
θ value	0.813845 (rank : 136)	NC score	0.014261 (rank : 154)
Query Neighborhood Hits	230	Target Neighborhood Hits	577	Shared Neighborhood Hits	36
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

ETV5_MOUSE
θ value	1.06291 (rank : 137)	NC score	0.011047 (rank : 169)
Query Neighborhood Hits	230	Target Neighborhood Hits	328	Shared Neighborhood Hits	36
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

TLE1_HUMAN
θ value	1.06291 (rank : 138)	NC score	0.008723 (rank : 184)
Query Neighborhood Hits	230	Target Neighborhood Hits	485	Shared Neighborhood Hits	31
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

TS13_MOUSE
θ value	1.06291 (rank : 139)	NC score	0.021068 (rank : 130)
Query Neighborhood Hits	230	Target Neighborhood Hits	191	Shared Neighborhood Hits	14
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

FOXP4_MOUSE
θ value	1.38821 (rank : 140)	NC score	0.005319 (rank : 198)
Query Neighborhood Hits	230	Target Neighborhood Hits	211	Shared Neighborhood Hits	16
SwissProt Accessions	Q9DBY0, Q80V92, Q8CG10, Q8CIS1	Gene names	Foxp4
Domain Architecture	No domain graphic available
Description	Forkhead box protein P4 (Fork head-related protein like A) (mFKHLA).

MLL2_HUMAN
θ value	1.38821 (rank : 141)	NC score	0.024314 (rank : 124)
Query Neighborhood Hits	230	Target Neighborhood Hits	1788	Shared Neighborhood Hits	98
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MUCDL_HUMAN
θ value	1.38821 (rank : 142)	NC score	0.018992 (rank : 137)
Query Neighborhood Hits	230	Target Neighborhood Hits	777	Shared Neighborhood Hits	59
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NCOR1_MOUSE
θ value	1.38821 (rank : 143)	NC score	0.013632 (rank : 156)
Query Neighborhood Hits	230	Target Neighborhood Hits	521	Shared Neighborhood Hits	29
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

NOTC3_HUMAN
θ value	1.38821 (rank : 144)	NC score	-0.001931 (rank : 218)
Query Neighborhood Hits	230	Target Neighborhood Hits	1062	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

PATZ1_HUMAN
θ value	1.38821 (rank : 145)	NC score	-0.007569 (rank : 228)
Query Neighborhood Hits	230	Target Neighborhood Hits	802	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HBE1, Q9HBE2, Q9HBE3, Q9P1A9, Q9UDU0, Q9Y529	Gene names	PATZ1, PATZ, RIAZ, ZBTB19, ZNF278, ZSG
Domain Architecture
Description	POZ-, AT hook-, and zinc finger-containing protein 1 (Zinc finger protein 278) (Zinc finger sarcoma gene protein) (BTB-POZ domain zinc finger transcription factor) (Protein kinase A RI-subunit alpha- associated protein) (Zinc finger and BTB domain-containing protein 19).

TLE1_MOUSE
θ value	1.38821 (rank : 146)	NC score	0.009955 (rank : 175)
Query Neighborhood Hits	230	Target Neighborhood Hits	491	Shared Neighborhood Hits	31
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

ZIM10_HUMAN
θ value	1.38821 (rank : 147)	NC score	0.025146 (rank : 122)
Query Neighborhood Hits	230	Target Neighborhood Hits	577	Shared Neighborhood Hits	58
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

F100B_MOUSE
θ value	1.81305 (rank : 148)	NC score	0.017638 (rank : 144)
Query Neighborhood Hits	230	Target Neighborhood Hits	91	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BQH4, Q3UMH5	Gene names	Fam100b
Domain Architecture	No domain graphic available
Description	Protein FAM100B.

PIGQ_HUMAN
θ value	1.81305 (rank : 149)	NC score	0.009739 (rank : 177)
Query Neighborhood Hits	230	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BRB3, O14927, Q96G00, Q96S22, Q9UJH4	Gene names	PIGQ, GPI1
Domain Architecture
Description	Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (EC 2.4.1.198) (Phosphatidylinositol-glycan biosynthesis class Q protein) (PIG-Q) (N-acetylglucosamyl transferase component GPI1).

PKD1_HUMAN
θ value	1.81305 (rank : 150)	NC score	0.007077 (rank : 192)
Query Neighborhood Hits	230	Target Neighborhood Hits	387	Shared Neighborhood Hits	6
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

SCUB3_HUMAN
θ value	1.81305 (rank : 151)	NC score	0.001301 (rank : 212)
Query Neighborhood Hits	230	Target Neighborhood Hits	428	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

ZIM10_MOUSE
θ value	1.81305 (rank : 152)	NC score	0.024376 (rank : 123)
Query Neighborhood Hits	230	Target Neighborhood Hits	430	Shared Neighborhood Hits	54
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

CJ108_HUMAN
θ value	2.36792 (rank : 153)	NC score	0.015437 (rank : 150)
Query Neighborhood Hits	230	Target Neighborhood Hits	165	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

MKL1_MOUSE
θ value	2.36792 (rank : 154)	NC score	0.019686 (rank : 135)
Query Neighborhood Hits	230	Target Neighborhood Hits	667	Shared Neighborhood Hits	50
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

MLL3_MOUSE
θ value	2.36792 (rank : 155)	NC score	0.019896 (rank : 132)
Query Neighborhood Hits	230	Target Neighborhood Hits	1399	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PAX5_HUMAN
θ value	2.36792 (rank : 156)	NC score	0.008950 (rank : 183)
Query Neighborhood Hits	230	Target Neighborhood Hits	106	Shared Neighborhood Hits	10
SwissProt Accessions	Q02548, O75933	Gene names	PAX5
Domain Architecture
Description	Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP).

PAX5_MOUSE
θ value	2.36792 (rank : 157)	NC score	0.008954 (rank : 182)
Query Neighborhood Hits	230	Target Neighborhood Hits	106	Shared Neighborhood Hits	10
SwissProt Accessions	Q02650	Gene names	Pax5, Pax-5
Domain Architecture
Description	Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP).

PER3_HUMAN
θ value	2.36792 (rank : 158)	NC score	0.019533 (rank : 136)
Query Neighborhood Hits	230	Target Neighborhood Hits	479	Shared Neighborhood Hits	47
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

SCUB3_MOUSE
θ value	2.36792 (rank : 159)	NC score	0.000954 (rank : 214)
Query Neighborhood Hits	230	Target Neighborhood Hits	442	Shared Neighborhood Hits	10
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SOX30_MOUSE
θ value	2.36792 (rank : 160)	NC score	0.007982 (rank : 188)
Query Neighborhood Hits	230	Target Neighborhood Hits	374	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

ZN598_MOUSE
θ value	2.36792 (rank : 161)	NC score	0.013441 (rank : 158)
Query Neighborhood Hits	230	Target Neighborhood Hits	255	Shared Neighborhood Hits	20
SwissProt Accessions	Q80YR4, Q6KAT0, Q8R3S1	Gene names	Znf598, Zfp598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

CJ093_HUMAN
θ value	3.0926 (rank : 162)	NC score	0.011691 (rank : 164)
Query Neighborhood Hits	230	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SR76, Q86ST2, Q8N777	Gene names	C10orf93
Domain Architecture	No domain graphic available
Description	Protein C10orf93.

EDNRB_MOUSE
θ value	3.0926 (rank : 163)	NC score	-0.006034 (rank : 225)
Query Neighborhood Hits	230	Target Neighborhood Hits	587	Shared Neighborhood Hits	2
SwissProt Accessions	P48302, Q542M3	Gene names	Ednrb
Domain Architecture
Description	Endothelin B receptor precursor (ET-B) (Endothelin receptor Non- selective type).

HELZ_HUMAN
θ value	3.0926 (rank : 164)	NC score	0.008341 (rank : 187)
Query Neighborhood Hits	230	Target Neighborhood Hits	198	Shared Neighborhood Hits	20
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

LAMC2_HUMAN
θ value	3.0926 (rank : 165)	NC score	0.001609 (rank : 211)
Query Neighborhood Hits	230	Target Neighborhood Hits	715	Shared Neighborhood Hits	19
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

MMAC_HUMAN
θ value	3.0926 (rank : 166)	NC score	0.012821 (rank : 160)
Query Neighborhood Hits	230	Target Neighborhood Hits	76	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y4U1, Q5T157, Q9BRQ7	Gene names	MMACHC
Domain Architecture	No domain graphic available
Description	Methylmalonic aciduria and homocystinuria type C protein.

MYO15_MOUSE
θ value	3.0926 (rank : 167)	NC score	0.005619 (rank : 196)
Query Neighborhood Hits	230	Target Neighborhood Hits	467	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PDZD2_HUMAN
θ value	3.0926 (rank : 168)	NC score	0.004427 (rank : 204)
Query Neighborhood Hits	230	Target Neighborhood Hits	772	Shared Neighborhood Hits	39
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PELP1_MOUSE
θ value	3.0926 (rank : 169)	NC score	0.026959 (rank : 117)
Query Neighborhood Hits	230	Target Neighborhood Hits	709	Shared Neighborhood Hits	71
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

RP1L1_HUMAN
θ value	3.0926 (rank : 170)	NC score	0.009894 (rank : 176)
Query Neighborhood Hits	230	Target Neighborhood Hits	1072	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

TCF19_HUMAN
θ value	3.0926 (rank : 171)	NC score	0.010127 (rank : 172)
Query Neighborhood Hits	230	Target Neighborhood Hits	124	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y242, Q13176, Q15967, Q5SQ89, Q5STD6, Q5STF5, Q9BUM2, Q9UBH7	Gene names	TCF19, SC1
Domain Architecture
Description	Transcription factor 19 (Transcription factor SC1).

ZBTB3_HUMAN
θ value	3.0926 (rank : 172)	NC score	-0.005201 (rank : 223)
Query Neighborhood Hits	230	Target Neighborhood Hits	910	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

CBP_HUMAN
θ value	4.03905 (rank : 173)	NC score	0.030682 (rank : 109)
Query Neighborhood Hits	230	Target Neighborhood Hits	941	Shared Neighborhood Hits	75
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DOK1_MOUSE
θ value	4.03905 (rank : 174)	NC score	0.010682 (rank : 170)
Query Neighborhood Hits	230	Target Neighborhood Hits	82	Shared Neighborhood Hits	9
SwissProt Accessions	P97465, Q9R213	Gene names	Dok1, Dok
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)).

GP123_HUMAN
θ value	4.03905 (rank : 175)	NC score	0.005160 (rank : 201)
Query Neighborhood Hits	230	Target Neighborhood Hits	120	Shared Neighborhood Hits	5
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

IF4G1_MOUSE
θ value	4.03905 (rank : 176)	NC score	0.013506 (rank : 157)
Query Neighborhood Hits	230	Target Neighborhood Hits	534	Shared Neighborhood Hits	43
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

K1802_MOUSE
θ value	4.03905 (rank : 177)	NC score	0.008429 (rank : 186)
Query Neighborhood Hits	230	Target Neighborhood Hits	1596	Shared Neighborhood Hits	71
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LTK_MOUSE
θ value	4.03905 (rank : 178)	NC score	-0.007345 (rank : 227)
Query Neighborhood Hits	230	Target Neighborhood Hits	770	Shared Neighborhood Hits	6
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

PCLO_HUMAN
θ value	4.03905 (rank : 179)	NC score	0.014434 (rank : 153)
Query Neighborhood Hits	230	Target Neighborhood Hits	2046	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PI5PA_HUMAN
θ value	4.03905 (rank : 180)	NC score	0.023983 (rank : 125)
Query Neighborhood Hits	230	Target Neighborhood Hits	749	Shared Neighborhood Hits	73
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PINC_HUMAN
θ value	4.03905 (rank : 181)	NC score	0.000573 (rank : 215)
Query Neighborhood Hits	230	Target Neighborhood Hits	231	Shared Neighborhood Hits	3
SwissProt Accessions	P48059, Q53TE0, Q9BS44	Gene names	LIMS1
Domain Architecture
Description	Protein PINCH (Particularly interesting new Cys-His protein) (LIM and senescent cell antigen-like domains 1) (NY-REN-48 antigen).

S23IP_MOUSE
θ value	4.03905 (rank : 182)	NC score	0.019885 (rank : 133)
Query Neighborhood Hits	230	Target Neighborhood Hits	363	Shared Neighborhood Hits	46
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

SC24C_HUMAN
θ value	4.03905 (rank : 183)	NC score	0.030037 (rank : 110)
Query Neighborhood Hits	230	Target Neighborhood Hits	662	Shared Neighborhood Hits	60
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SNPC4_MOUSE
θ value	4.03905 (rank : 184)	NC score	0.011160 (rank : 167)
Query Neighborhood Hits	230	Target Neighborhood Hits	237	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

TARSH_HUMAN
θ value	4.03905 (rank : 185)	NC score	0.015021 (rank : 152)
Query Neighborhood Hits	230	Target Neighborhood Hits	768	Shared Neighborhood Hits	52
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TCF7_MOUSE
θ value	4.03905 (rank : 186)	NC score	0.003302 (rank : 205)
Query Neighborhood Hits	230	Target Neighborhood Hits	277	Shared Neighborhood Hits	19
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

TENS1_HUMAN
θ value	4.03905 (rank : 187)	NC score	0.016271 (rank : 147)
Query Neighborhood Hits	230	Target Neighborhood Hits	400	Shared Neighborhood Hits	44
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

TPO_MOUSE
θ value	4.03905 (rank : 188)	NC score	0.015189 (rank : 151)
Query Neighborhood Hits	230	Target Neighborhood Hits	258	Shared Neighborhood Hits	22
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

CUTC_HUMAN
θ value	5.27518 (rank : 189)	NC score	0.009644 (rank : 178)
Query Neighborhood Hits	230	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NTM9, Q9Y321	Gene names	CUTC
Domain Architecture	No domain graphic available
Description	Copper homeostasis protein cutC homolog.

FXL19_MOUSE
θ value	5.27518 (rank : 190)	NC score	0.005474 (rank : 197)
Query Neighborhood Hits	230	Target Neighborhood Hits	217	Shared Neighborhood Hits	19
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

GLI2_HUMAN
θ value	5.27518 (rank : 191)	NC score	-0.005046 (rank : 222)
Query Neighborhood Hits	230	Target Neighborhood Hits	971	Shared Neighborhood Hits	36
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

JPH2_HUMAN
θ value	5.27518 (rank : 192)	NC score	0.009965 (rank : 174)
Query Neighborhood Hits	230	Target Neighborhood Hits	639	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

MEF2B_HUMAN
θ value	5.27518 (rank : 193)	NC score	0.012843 (rank : 159)
Query Neighborhood Hits	230	Target Neighborhood Hits	150	Shared Neighborhood Hits	24
SwissProt Accessions	Q02080	Gene names	MEF2B, XMEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2B (Serum response factor-like protein 2) (XMEF2) (RSRFR2).

NFH_MOUSE
θ value	5.27518 (rank : 194)	NC score	0.005696 (rank : 195)
Query Neighborhood Hits	230	Target Neighborhood Hits	2247	Shared Neighborhood Hits	74
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PSMF1_MOUSE
θ value	5.27518 (rank : 195)	NC score	0.013983 (rank : 155)
Query Neighborhood Hits	230	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BHL8, Q8C0G9	Gene names	Psmf1
Domain Architecture	No domain graphic available
Description	Proteasome inhibitor PI31 subunit.

SLIT3_HUMAN
θ value	5.27518 (rank : 196)	NC score	-0.003898 (rank : 220)
Query Neighborhood Hits	230	Target Neighborhood Hits	682	Shared Neighborhood Hits	12
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

ZIMP7_MOUSE
θ value	5.27518 (rank : 197)	NC score	0.018929 (rank : 138)
Query Neighborhood Hits	230	Target Neighborhood Hits	566	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ARI1A_HUMAN
θ value	6.88961 (rank : 198)	NC score	0.025576 (rank : 120)
Query Neighborhood Hits	230	Target Neighborhood Hits	787	Shared Neighborhood Hits	81
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

CRTC1_HUMAN
θ value	6.88961 (rank : 199)	NC score	0.023333 (rank : 126)
Query Neighborhood Hits	230	Target Neighborhood Hits	319	Shared Neighborhood Hits	52
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

ETV3_HUMAN
θ value	6.88961 (rank : 200)	NC score	0.005070 (rank : 202)
Query Neighborhood Hits	230	Target Neighborhood Hits	312	Shared Neighborhood Hits	23
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

FOXP4_HUMAN
θ value	6.88961 (rank : 201)	NC score	0.004837 (rank : 203)
Query Neighborhood Hits	230	Target Neighborhood Hits	246	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IVH2, Q96E19	Gene names	FOXP4, FKHLA
Domain Architecture
Description	Forkhead box protein P4 (Fork head-related protein-like A).

GNAS1_MOUSE
θ value	6.88961 (rank : 202)	NC score	0.011572 (rank : 165)
Query Neighborhood Hits	230	Target Neighborhood Hits	651	Shared Neighborhood Hits	53
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

JIP2_HUMAN
θ value	6.88961 (rank : 203)	NC score	0.007344 (rank : 191)
Query Neighborhood Hits	230	Target Neighborhood Hits	288	Shared Neighborhood Hits	21
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

PAX1_MOUSE
θ value	6.88961 (rank : 204)	NC score	0.009997 (rank : 173)
Query Neighborhood Hits	230	Target Neighborhood Hits	69	Shared Neighborhood Hits	10
SwissProt Accessions	P09084, Q9R2B1	Gene names	Pax1, Pax-1
Domain Architecture
Description	Paired box protein Pax-1.

SAPS1_HUMAN
θ value	6.88961 (rank : 205)	NC score	0.012809 (rank : 161)
Query Neighborhood Hits	230	Target Neighborhood Hits	704	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SEM6B_MOUSE
θ value	6.88961 (rank : 206)	NC score	-0.000599 (rank : 216)
Query Neighborhood Hits	230	Target Neighborhood Hits	200	Shared Neighborhood Hits	8
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

SRBP1_MOUSE
θ value	6.88961 (rank : 207)	NC score	0.018746 (rank : 139)
Query Neighborhood Hits	230	Target Neighborhood Hits	384	Shared Neighborhood Hits	42
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

TENX_HUMAN
θ value	6.88961 (rank : 208)	NC score	-0.002590 (rank : 219)
Query Neighborhood Hits	230	Target Neighborhood Hits	789	Shared Neighborhood Hits	19
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TIE1_MOUSE
θ value	6.88961 (rank : 209)	NC score	-0.009588 (rank : 229)
Query Neighborhood Hits	230	Target Neighborhood Hits	1266	Shared Neighborhood Hits	13
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TLE4_HUMAN
θ value	6.88961 (rank : 210)	NC score	0.009231 (rank : 180)
Query Neighborhood Hits	230	Target Neighborhood Hits	477	Shared Neighborhood Hits	29
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

TLE4_MOUSE
θ value	6.88961 (rank : 211)	NC score	0.009404 (rank : 179)
Query Neighborhood Hits	230	Target Neighborhood Hits	482	Shared Neighborhood Hits	30
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

ATS7_HUMAN
θ value	8.99809 (rank : 212)	NC score	0.002992 (rank : 207)
Query Neighborhood Hits	230	Target Neighborhood Hits	169	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

CAC1G_HUMAN
θ value	8.99809 (rank : 213)	NC score	0.003024 (rank : 206)
Query Neighborhood Hits	230	Target Neighborhood Hits	587	Shared Neighborhood Hits	37
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CN037_MOUSE
θ value	8.99809 (rank : 214)	NC score	0.012097 (rank : 162)
Query Neighborhood Hits	230	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

CNTRB_MOUSE
θ value	8.99809 (rank : 215)	NC score	-0.001275 (rank : 217)
Query Neighborhood Hits	230	Target Neighborhood Hits	1029	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CO9A3_HUMAN
θ value	8.99809 (rank : 216)	NC score	0.012002 (rank : 163)
Query Neighborhood Hits	230	Target Neighborhood Hits	361	Shared Neighborhood Hits	45
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

CRSP2_HUMAN
θ value	8.99809 (rank : 217)	NC score	0.015737 (rank : 149)
Query Neighborhood Hits	230	Target Neighborhood Hits	380	Shared Neighborhood Hits	45
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

CTND2_HUMAN
θ value	8.99809 (rank : 218)	NC score	0.005224 (rank : 200)
Query Neighborhood Hits	230	Target Neighborhood Hits	333	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

EP300_HUMAN
θ value	8.99809 (rank : 219)	NC score	0.037692 (rank : 104)
Query Neighborhood Hits	230	Target Neighborhood Hits	821	Shared Neighborhood Hits	81
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

GLIS3_MOUSE
θ value	8.99809 (rank : 220)	NC score	-0.007257 (rank : 226)
Query Neighborhood Hits	230	Target Neighborhood Hits	861	Shared Neighborhood Hits	31
SwissProt Accessions	Q6XP49, Q8BI60	Gene names	Glis3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3).

GSH2_MOUSE
θ value	8.99809 (rank : 221)	NC score	-0.004549 (rank : 221)
Query Neighborhood Hits	230	Target Neighborhood Hits	319	Shared Neighborhood Hits	3
SwissProt Accessions	P31316	Gene names	Gsh2, Gsh-2
Domain Architecture
Description	Homeobox protein GSH-2.

IRF3_HUMAN
θ value	8.99809 (rank : 222)	NC score	0.001159 (rank : 213)
Query Neighborhood Hits	230	Target Neighborhood Hits	129	Shared Neighborhood Hits	7
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

LRC50_HUMAN
θ value	8.99809 (rank : 223)	NC score	0.006229 (rank : 194)
Query Neighborhood Hits	230	Target Neighborhood Hits	275	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NEP3, Q69YI8, Q69YJ0, Q96LP3	Gene names	LRRC50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

MEGF9_MOUSE
θ value	8.99809 (rank : 224)	NC score	0.006977 (rank : 193)
Query Neighborhood Hits	230	Target Neighborhood Hits	896	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NEK6_MOUSE
θ value	8.99809 (rank : 225)	NC score	-0.009998 (rank : 230)
Query Neighborhood Hits	230	Target Neighborhood Hits	851	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ES70, Q3TCE9, Q8C6E6, Q9D0E2, Q9DBI8	Gene names	Nek6
Domain Architecture
Description	Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (NimA-related protein kinase 6).

PYGO1_HUMAN
θ value	8.99809 (rank : 226)	NC score	0.007748 (rank : 190)
Query Neighborhood Hits	230	Target Neighborhood Hits	90	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y3Y4	Gene names	PYGO1
Domain Architecture
Description	Pygopus homolog 1.

PYGO1_MOUSE
θ value	8.99809 (rank : 227)	NC score	0.011095 (rank : 168)
Query Neighborhood Hits	230	Target Neighborhood Hits	69	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D0P5	Gene names	Pygo1
Domain Architecture
Description	Pygopus homolog 1.

RFFL_HUMAN
θ value	8.99809 (rank : 228)	NC score	0.002968 (rank : 208)
Query Neighborhood Hits	230	Target Neighborhood Hits	175	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

SSBP4_HUMAN
θ value	8.99809 (rank : 229)	NC score	0.015955 (rank : 148)
Query Neighborhood Hits	230	Target Neighborhood Hits	753	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

TNR6A_HUMAN
θ value	8.99809 (rank : 230)	NC score	0.011528 (rank : 166)
Query Neighborhood Hits	230	Target Neighborhood Hits	343	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

Hits sorted by NC score

RXRB_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	230	Target Neighborhood Hits	230	Shared Neighborhood Hits	230
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

RXRB_HUMAN
NC score	0.994094 (rank : 2)	θ value	2.74423e-182 (rank : 2)
Query Neighborhood Hits	230	Target Neighborhood Hits	280	Shared Neighborhood Hits	184
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

RXRA_MOUSE
NC score	0.992293 (rank : 3)	θ value	3.72618e-163 (rank : 4)
Query Neighborhood Hits	230	Target Neighborhood Hits	129	Shared Neighborhood Hits	109
SwissProt Accessions	P28700	Gene names	Rxra, Nr2b1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

RXRG_MOUSE
NC score	0.991542 (rank : 4)	θ value	1.09172e-138 (rank : 6)
Query Neighborhood Hits	230	Target Neighborhood Hits	113	Shared Neighborhood Hits	100
SwissProt Accessions	P28705	Gene names	Rxrg, Nr2b3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

RXRG_HUMAN
NC score	0.991271 (rank : 5)	θ value	4.90052e-139 (rank : 5)
Query Neighborhood Hits	230	Target Neighborhood Hits	114	Shared Neighborhood Hits	99
SwissProt Accessions	P48443	Gene names	RXRG, NR2B3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

RXRA_HUMAN
NC score	0.989598 (rank : 6)	θ value	3.37019e-164 (rank : 3)
Query Neighborhood Hits	230	Target Neighborhood Hits	223	Shared Neighborhood Hits	112
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

HNF4G_MOUSE
NC score	0.978504 (rank : 7)	θ value	4.23606e-66 (rank : 14)
Query Neighborhood Hits	230	Target Neighborhood Hits	101	Shared Neighborhood Hits	98
SwissProt Accessions	Q9WUU6	Gene names	Hnf4g, Nr2a2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

HNF4G_HUMAN
NC score	0.978300 (rank : 8)	θ value	4.09345e-69 (rank : 7)
Query Neighborhood Hits	230	Target Neighborhood Hits	100	Shared Neighborhood Hits	98
SwissProt Accessions	Q14541, Q9UH81, Q9UIS6	Gene names	HNF4G, NR2A2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

HNF4A_MOUSE
NC score	0.977565 (rank : 9)	θ value	2.4834e-66 (rank : 13)
Query Neighborhood Hits	230	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	P49698	Gene names	Hnf4a, Hnf-4, Hnf4, Nr2a1, Tcf14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

HNF4A_HUMAN
NC score	0.977544 (rank : 10)	θ value	1.71981e-67 (rank : 12)
Query Neighborhood Hits	230	Target Neighborhood Hits	105	Shared Neighborhood Hits	98
SwissProt Accessions	P41235, O00659, O00723, Q14540, Q92653, Q92654, Q92655, Q99864, Q9NQH0	Gene names	HNF4A, HNF4, NR2A1, TCF14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

EAR2_HUMAN
NC score	0.976327 (rank : 11)	θ value	8.55514e-59 (rank : 16)
Query Neighborhood Hits	230	Target Neighborhood Hits	106	Shared Neighborhood Hits	99
SwissProt Accessions	P10588, Q9BUE8	Gene names	NR2F6, EAR2, ERBAL2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

COT2_HUMAN
NC score	0.975931 (rank : 12)	θ value	6.98233e-69 (rank : 10)
Query Neighborhood Hits	230	Target Neighborhood Hits	135	Shared Neighborhood Hits	102
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT2_MOUSE
NC score	0.975931 (rank : 13)	θ value	6.98233e-69 (rank : 11)
Query Neighborhood Hits	230	Target Neighborhood Hits	135	Shared Neighborhood Hits	102
SwissProt Accessions	P43135	Gene names	Nr2f2, Aporp1, Arp-1, Arp1, Tfcoup2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

EAR2_MOUSE
NC score	0.975136 (rank : 14)	θ value	3.84025e-59 (rank : 15)
Query Neighborhood Hits	230	Target Neighborhood Hits	104	Shared Neighborhood Hits	99
SwissProt Accessions	P43136, Q61504	Gene names	Nr2f6, Ear-2, Ear2, Erbal2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

COT1_MOUSE
NC score	0.974917 (rank : 15)	θ value	5.34618e-69 (rank : 9)
Query Neighborhood Hits	230	Target Neighborhood Hits	160	Shared Neighborhood Hits	103
SwissProt Accessions	Q60632, Q61438	Gene names	Nr2f1, Erbal3, Tfcoup1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I).

COT1_HUMAN
NC score	0.974797 (rank : 16)	θ value	5.34618e-69 (rank : 8)
Query Neighborhood Hits	230	Target Neighborhood Hits	159	Shared Neighborhood Hits	105
SwissProt Accessions	P10589	Gene names	NR2F1, EAR3, ERBAL3, TFCOUP1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I) (V-ERBA-related protein EAR-3).

NR2E3_HUMAN
NC score	0.972607 (rank : 17)	θ value	2.84797e-54 (rank : 17)
Query Neighborhood Hits	230	Target Neighborhood Hits	102	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Y5X4, Q9UHM4	Gene names	NR2E3, PNR, RNR
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

NR2E3_MOUSE
NC score	0.970879 (rank : 18)	θ value	7.75577e-52 (rank : 21)
Query Neighborhood Hits	230	Target Neighborhood Hits	113	Shared Neighborhood Hits	98
SwissProt Accessions	Q9QXZ7	Gene names	Nr2e3, Pnr, Rnr
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

NR2E1_MOUSE
NC score	0.969625 (rank : 19)	θ value	4.25575e-50 (rank : 23)
Query Neighborhood Hits	230	Target Neighborhood Hits	106	Shared Neighborhood Hits	99
SwissProt Accessions	Q64104	Gene names	Nr2e1, Tll, Tlx
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (mTll).

NR2E1_HUMAN
NC score	0.967348 (rank : 20)	θ value	1.46607e-42 (rank : 34)
Query Neighborhood Hits	230	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y466	Gene names	NR2E1, TLX
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (hTll).

ERR3_HUMAN
NC score	0.959968 (rank : 21)	θ value	8.28633e-54 (rank : 18)
Query Neighborhood Hits	230	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P62508, O75454, O96021, Q68DA0, Q6P274, Q6PK28, Q6TS38, Q9R1F3, Q9UNJ4	Gene names	ESRRG, ERR3, ERRG2, KIAA0832, NR3B3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (ERR gamma-2).

ERR3_MOUSE
NC score	0.959968 (rank : 22)	θ value	8.28633e-54 (rank : 19)
Query Neighborhood Hits	230	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P62509, O75454, O96021, Q8CHC9, Q9R1F3	Gene names	Esrrg, Err3, Kiaa0832, Nr3b3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3).

ERR2_MOUSE
NC score	0.959500 (rank : 23)	θ value	3.48141e-52 (rank : 20)
Query Neighborhood Hits	230	Target Neighborhood Hits	109	Shared Neighborhood Hits	98
SwissProt Accessions	Q61539, O09067, O09146	Gene names	Esrrb, Err-2, Err2, Nr3b2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2).

ERR2_HUMAN
NC score	0.957240 (rank : 24)	θ value	1.91031e-50 (rank : 22)
Query Neighborhood Hits	230	Target Neighborhood Hits	108	Shared Neighborhood Hits	99
SwissProt Accessions	O95718, Q9HCB4	Gene names	ESRRB, ERRB2, NR3B2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2) (ERR beta-2).

ERR1_HUMAN
NC score	0.955297 (rank : 25)	θ value	2.58786e-39 (rank : 36)
Query Neighborhood Hits	230	Target Neighborhood Hits	157	Shared Neighborhood Hits	101
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

RARB_HUMAN
NC score	0.944729 (rank : 26)	θ value	1.23823e-49 (rank : 24)
Query Neighborhood Hits	230	Target Neighborhood Hits	118	Shared Neighborhood Hits	94
SwissProt Accessions	P10826, P12891, Q00989, Q15298, Q9UN48	Gene names	RARB, HAP, NR1B2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta) (RAR-epsilon) (HBV-activated protein).

RARB_MOUSE
NC score	0.944645 (rank : 27)	θ value	1.23823e-49 (rank : 25)
Query Neighborhood Hits	230	Target Neighborhood Hits	109	Shared Neighborhood Hits	95
SwissProt Accessions	P22605, P11417, P22604	Gene names	Rarb, Nr1b2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta).

RARA_MOUSE
NC score	0.944362 (rank : 28)	θ value	1.788e-48 (rank : 26)
Query Neighborhood Hits	230	Target Neighborhood Hits	113	Shared Neighborhood Hits	98
SwissProt Accessions	P11416, P22603	Gene names	Rara, Nr1b1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARA_HUMAN
NC score	0.944172 (rank : 29)	θ value	2.3352e-48 (rank : 27)
Query Neighborhood Hits	230	Target Neighborhood Hits	118	Shared Neighborhood Hits	97
SwissProt Accessions	P10276, P78456, Q13440, Q13441, Q9NQS0	Gene names	RARA, NR1B1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARG2_HUMAN
NC score	0.943843 (rank : 30)	θ value	8.30557e-46 (rank : 31)
Query Neighborhood Hits	230	Target Neighborhood Hits	109	Shared Neighborhood Hits	95
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

RARG1_HUMAN
NC score	0.943706 (rank : 31)	θ value	8.30557e-46 (rank : 30)
Query Neighborhood Hits	230	Target Neighborhood Hits	107	Shared Neighborhood Hits	95
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARG2_MOUSE
NC score	0.943610 (rank : 32)	θ value	1.28137e-46 (rank : 29)
Query Neighborhood Hits	230	Target Neighborhood Hits	114	Shared Neighborhood Hits	96
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

RARG1_MOUSE
NC score	0.943338 (rank : 33)	θ value	1.28137e-46 (rank : 28)
Query Neighborhood Hits	230	Target Neighborhood Hits	113	Shared Neighborhood Hits	96
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

NR4A3_MOUSE
NC score	0.943178 (rank : 34)	θ value	2.58786e-39 (rank : 37)
Query Neighborhood Hits	230	Target Neighborhood Hits	127	Shared Neighborhood Hits	103
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

NR4A2_MOUSE
NC score	0.943175 (rank : 35)	θ value	2.95404e-43 (rank : 33)
Query Neighborhood Hits	230	Target Neighborhood Hits	121	Shared Neighborhood Hits	99
SwissProt Accessions	Q06219, O08690	Gene names	Nr4a2, Nurr1
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (NUR- related factor 1).

NR4A2_HUMAN
NC score	0.943120 (rank : 36)	θ value	2.95404e-43 (rank : 32)
Query Neighborhood Hits	230	Target Neighborhood Hits	120	Shared Neighborhood Hits	99
SwissProt Accessions	P43354, Q16311	Gene names	NR4A2, NOT, NURR1, TINUR
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (Immediate-early response protein NOT) (Transcriptionally-inducible nuclear receptor).

NR4A3_HUMAN
NC score	0.942427 (rank : 37)	θ value	4.88048e-38 (rank : 38)
Query Neighborhood Hits	230	Target Neighborhood Hits	131	Shared Neighborhood Hits	102
SwissProt Accessions	Q92570, Q12935, Q14979, Q16420, Q4VXA9, Q9UEK2, Q9UEK3	Gene names	NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1) (Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphan receptor).

ESR2_HUMAN
NC score	0.940507 (rank : 38)	θ value	6.15952e-41 (rank : 35)
Query Neighborhood Hits	230	Target Neighborhood Hits	110	Shared Neighborhood Hits	97
SwissProt Accessions	Q92731, O60608, O60685, O60702, O60703, O75583, O75584, Q86Z31, Q9UEV6, Q9UHD3, Q9UQK9	Gene names	ESR2, ESTRB, NR3A2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

NR4A1_HUMAN
NC score	0.939476 (rank : 39)	θ value	1.6247e-33 (rank : 42)
Query Neighborhood Hits	230	Target Neighborhood Hits	133	Shared Neighborhood Hits	103
SwissProt Accessions	P22736	Gene names	NR4A1, GFRP1, HMR, NAK1
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Early response protein NAK1) (TR3 orphan receptor) (ST-59).

ESR2_MOUSE
NC score	0.938670 (rank : 40)	θ value	1.32909e-35 (rank : 39)
Query Neighborhood Hits	230	Target Neighborhood Hits	110	Shared Neighborhood Hits	96
SwissProt Accessions	O08537, O35635, O70519	Gene names	Esr2, Estrb, Nr3a2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

NR4A1_MOUSE
NC score	0.937113 (rank : 41)	θ value	2.86786e-30 (rank : 53)
Query Neighborhood Hits	230	Target Neighborhood Hits	128	Shared Neighborhood Hits	95
SwissProt Accessions	P12813	Gene names	Nr4a1, Gfrp, Hmr, N10, Nur77
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Nuclear hormone receptor NUR/77) (N10 nuclear protein).

ESR1_HUMAN
NC score	0.934228 (rank : 42)	θ value	1.46948e-34 (rank : 40)
Query Neighborhood Hits	230	Target Neighborhood Hits	105	Shared Neighborhood Hits	97
SwissProt Accessions	P03372, Q13511, Q14276, Q9NU51, Q9UDZ7, Q9UIS7	Gene names	ESR1, ESR, NR3A1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

ESR1_MOUSE
NC score	0.934091 (rank : 43)	θ value	1.0531e-32 (rank : 45)
Query Neighborhood Hits	230	Target Neighborhood Hits	104	Shared Neighborhood Hits	96
SwissProt Accessions	P19785, Q9JJT5, Q9QY51, Q9QY52	Gene names	Esr1, Esr, Estr, Estra, Nr3a1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

TR2_HUMAN
NC score	0.928996 (rank : 44)	θ value	1.08979e-29 (rank : 56)
Query Neighborhood Hits	230	Target Neighborhood Hits	110	Shared Neighborhood Hits	97
SwissProt Accessions	P13056	Gene names	NR2C1, TR2
Domain Architecture
Description	Orphan nuclear receptor TR2 (Testicular receptor 2).

NR6A1_HUMAN
NC score	0.928670 (rank : 45)	θ value	4.01107e-24 (rank : 70)
Query Neighborhood Hits	230	Target Neighborhood Hits	108	Shared Neighborhood Hits	98
SwissProt Accessions	Q15406, O00551, O00603, Q8NHQ0, Q92898, Q99802	Gene names	NR6A1, GCNF
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

NR6A1_MOUSE
NC score	0.928059 (rank : 46)	θ value	1.80048e-24 (rank : 67)
Query Neighborhood Hits	230	Target Neighborhood Hits	110	Shared Neighborhood Hits	98
SwissProt Accessions	Q64249	Gene names	Nr6a1, Gcnf
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

NR1H4_HUMAN
NC score	0.926758 (rank : 47)	θ value	1.2049e-28 (rank : 59)
Query Neighborhood Hits	230	Target Neighborhood Hits	112	Shared Neighborhood Hits	98
SwissProt Accessions	Q96RI1, Q8NFP5, Q8NFP6, Q92943	Gene names	NR1H4, BAR, FXR, HRR1, RIP14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

TR2_MOUSE
NC score	0.926242 (rank : 48)	θ value	4.89182e-30 (rank : 54)
Query Neighborhood Hits	230	Target Neighborhood Hits	100	Shared Neighborhood Hits	98
SwissProt Accessions	Q505F1, P97763, Q3UIJ7, Q4U1Z4, Q60927, Q62152, Q8VIJ3	Gene names	Nr2c1, Tr2, Tr2-11
Domain Architecture	No domain graphic available
Description	Orphan nuclear receptor TR2 (Testicular receptor 2) (mTR2).

NR1H4_MOUSE
NC score	0.926234 (rank : 49)	θ value	2.42779e-29 (rank : 57)
Query Neighborhood Hits	230	Target Neighborhood Hits	113	Shared Neighborhood Hits	98
SwissProt Accessions	Q60641, Q60642, Q60643	Gene names	Nr1h4, Bar, Fxr, Rip14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

NR1H3_HUMAN
NC score	0.926175 (rank : 50)	θ value	4.42448e-31 (rank : 50)
Query Neighborhood Hits	230	Target Neighborhood Hits	104	Shared Neighborhood Hits	95
SwissProt Accessions	Q13133, Q96H87	Gene names	NR1H3, LXRA
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

TR4_HUMAN
NC score	0.926023 (rank : 51)	θ value	5.40856e-29 (rank : 58)
Query Neighborhood Hits	230	Target Neighborhood Hits	117	Shared Neighborhood Hits	99
SwissProt Accessions	P49116, P55092	Gene names	NR2C2, TAK1, TR4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

TR4_MOUSE
NC score	0.925364 (rank : 52)	θ value	2.05525e-28 (rank : 61)
Query Neighborhood Hits	230	Target Neighborhood Hits	115	Shared Neighborhood Hits	99
SwissProt Accessions	P49117, P55093	Gene names	Nr2c2, Mtr2r1, Tak1, Tr4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

NR1H3_MOUSE
NC score	0.925361 (rank : 53)	θ value	1.6813e-30 (rank : 51)
Query Neighborhood Hits	230	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Z0Y9, Q9QUH7	Gene names	Nr1h3, Lxra
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

THA_HUMAN
NC score	0.923495 (rank : 54)	θ value	1.24399e-33 (rank : 41)
Query Neighborhood Hits	230	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	P10827, P21205, Q8N6A1, Q96H73	Gene names	THRA, ERBA1, NR1A1, THRA1
Domain Architecture
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1) (EAR-7) (EAR7).

THA_MOUSE
NC score	0.923432 (rank : 55)	θ value	1.6247e-33 (rank : 43)
Query Neighborhood Hits	230	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	P63058, P10685, P15827, P16416, P37241, Q63107, Q63195, Q63196, Q99146	Gene names	Thra, C-erba-alpha, Nr1a1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1).

NR1I3_HUMAN
NC score	0.923285 (rank : 56)	θ value	3.88503e-19 (rank : 88)
Query Neighborhood Hits	230	Target Neighborhood Hits	107	Shared Neighborhood Hits	99
SwissProt Accessions	Q14994	Gene names	NR1I3, CAR
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Constitutive activator of retinoid response) (Constitutive active response) (Orphan nuclear receptor MB67).

NR5A2_MOUSE
NC score	0.922989 (rank : 57)	θ value	1.2049e-28 (rank : 60)
Query Neighborhood Hits	230	Target Neighborhood Hits	107	Shared Neighborhood Hits	98
SwissProt Accessions	P45448	Gene names	Nr5a2, Lrh1
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Liver receptor homolog 1) (LRH-1).

NR5A2_HUMAN
NC score	0.921250 (rank : 58)	θ value	1.08979e-29 (rank : 55)
Query Neighborhood Hits	230	Target Neighborhood Hits	112	Shared Neighborhood Hits	99
SwissProt Accessions	O00482, O95642	Gene names	NR5A2, B1F, CPF, FTF
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Alpha-1-fetoprotein transcription factor) (Hepatocytic transcription factor) (B1-binding factor) (hB1F) (CYP7A promoter-binding factor) (Liver receptor homolog 1) (LRH-1).

STF1_MOUSE
NC score	0.921232 (rank : 59)	θ value	2.35151e-24 (rank : 69)
Query Neighborhood Hits	230	Target Neighborhood Hits	137	Shared Neighborhood Hits	111
SwissProt Accessions	P33242	Gene names	Nr5a1, Ftzf1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1) (Embryonal LTR-binding protein) (ELP) (Embryonal long terminal repeat- binding protein) (Steroid hydroxylase positive regulator).

STF1_HUMAN
NC score	0.918745 (rank : 60)	θ value	2.35151e-24 (rank : 68)
Query Neighborhood Hits	230	Target Neighborhood Hits	132	Shared Neighborhood Hits	107
SwissProt Accessions	Q13285, O15196	Gene names	NR5A1, AD4BP, FTZF1, SF1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1).

NR1I3_MOUSE
NC score	0.917741 (rank : 61)	θ value	1.80466e-16 (rank : 92)
Query Neighborhood Hits	230	Target Neighborhood Hits	103	Shared Neighborhood Hits	100
SwissProt Accessions	O35627, O35628	Gene names	Nr1i3, Car
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67).

THB2_HUMAN
NC score	0.917540 (rank : 62)	θ value	3.06405e-32 (rank : 46)
Query Neighborhood Hits	230	Target Neighborhood Hits	104	Shared Neighborhood Hits	100
SwissProt Accessions	P37243	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor beta-2.

THB1_HUMAN
NC score	0.917107 (rank : 63)	θ value	6.82597e-32 (rank : 47)
Query Neighborhood Hits	230	Target Neighborhood Hits	106	Shared Neighborhood Hits	100
SwissProt Accessions	P10828, Q13986	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture
Description	Thyroid hormone receptor beta-1.

PPARA_HUMAN
NC score	0.916413 (rank : 64)	θ value	4.72714e-33 (rank : 44)
Query Neighborhood Hits	230	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q07869, Q16241, Q92486, Q92689, Q9Y3N1	Gene names	PPARA, NR1C1, PPAR
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

THB1_MOUSE
NC score	0.915944 (rank : 65)	θ value	1.52067e-31 (rank : 48)
Query Neighborhood Hits	230	Target Neighborhood Hits	105	Shared Neighborhood Hits	98
SwissProt Accessions	P37242	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-1.

THB2_MOUSE
NC score	0.915928 (rank : 66)	θ value	1.52067e-31 (rank : 49)
Query Neighborhood Hits	230	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P37244	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-2.

PPARA_MOUSE
NC score	0.915217 (rank : 67)	θ value	2.19584e-30 (rank : 52)
Query Neighborhood Hits	230	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	P23204	Gene names	Ppara, Nr1c1, Ppar
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

NR1H2_MOUSE
NC score	0.913589 (rank : 68)	θ value	2.12685e-25 (rank : 63)
Query Neighborhood Hits	230	Target Neighborhood Hits	109	Shared Neighborhood Hits	98
SwissProt Accessions	Q60644	Gene names	Nr1h2, Lxrb, Rip15, Unr, Unr2
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Retinoid X receptor-interacting protein No.15).

NR1D1_HUMAN
NC score	0.911964 (rank : 69)	θ value	3.17815e-21 (rank : 85)
Query Neighborhood Hits	230	Target Neighborhood Hits	140	Shared Neighborhood Hits	103
SwissProt Accessions	P20393, Q15304	Gene names	NR1D1, EAR1, HREV, THRAL
Domain Architecture
Description	Orphan nuclear receptor NR1D1 (V-erbA-related protein EAR-1) (Rev- erbA-alpha).

PPARD_HUMAN
NC score	0.910977 (rank : 70)	θ value	6.40375e-22 (rank : 81)
Query Neighborhood Hits	230	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q03181, Q7Z5K0, Q9BUD4	Gene names	PPARD, NR1C2, PPARB
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1) (NUCI).

PPARD_MOUSE
NC score	0.908833 (rank : 71)	θ value	1.09232e-21 (rank : 82)
Query Neighborhood Hits	230	Target Neighborhood Hits	103	Shared Neighborhood Hits	95
SwissProt Accessions	P35396, P37239	Gene names	Ppard, Nr1c2, Pparb
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1).

PPARG_HUMAN
NC score	0.908830 (rank : 72)	θ value	3.75424e-22 (rank : 79)
Query Neighborhood Hits	230	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37231, O00684, O00710, O14515, Q15178, Q15179, Q15180, Q15832, Q86U60, Q96J12	Gene names	PPARG, NR1C3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

PPARG_MOUSE
NC score	0.908435 (rank : 73)	θ value	3.75424e-22 (rank : 80)
Query Neighborhood Hits	230	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37238	Gene names	Pparg, Nr1c3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

NR1H2_HUMAN
NC score	0.907006 (rank : 74)	θ value	4.02038e-16 (rank : 93)
Query Neighborhood Hits	230	Target Neighborhood Hits	114	Shared Neighborhood Hits	100
SwissProt Accessions	P55055, Q12970	Gene names	NR1H2, LXRB, NER, UNR
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Nuclear receptor NER).

NR1D2_HUMAN
NC score	0.904322 (rank : 75)	θ value	1.86321e-21 (rank : 83)
Query Neighborhood Hits	230	Target Neighborhood Hits	115	Shared Neighborhood Hits	94
SwissProt Accessions	Q14995, O00402, Q86XD4	Gene names	NR1D2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (EAR-1R) (Orphan nuclear hormone receptor BD73).

NR1D2_MOUSE
NC score	0.901895 (rank : 76)	θ value	1.86321e-21 (rank : 84)
Query Neighborhood Hits	230	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	Q60674, Q60646	Gene names	Nr1d2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (Orphan nuclear receptor RVR).

RORG_MOUSE
NC score	0.901104 (rank : 77)	θ value	6.84181e-24 (rank : 75)
Query Neighborhood Hits	230	Target Neighborhood Hits	107	Shared Neighborhood Hits	95
SwissProt Accessions	P51450, Q61027, Q91YT5, Q9QXD9, Q9R177	Gene names	Rorc, Nr1f3, Rorg, Thor
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma) (Thymus orphan receptor) (TOR).

PXR_MOUSE
NC score	0.901025 (rank : 78)	θ value	1.058e-16 (rank : 91)
Query Neighborhood Hits	230	Target Neighborhood Hits	107	Shared Neighborhood Hits	97
SwissProt Accessions	O54915	Gene names	Nr1i2, Pxr
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor).

VDR_HUMAN
NC score	0.900837 (rank : 79)	θ value	1.63225e-17 (rank : 89)
Query Neighborhood Hits	230	Target Neighborhood Hits	112	Shared Neighborhood Hits	96
SwissProt Accessions	P11473	Gene names	VDR, NR1I1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

VDR_MOUSE
NC score	0.899738 (rank : 80)	θ value	6.20254e-17 (rank : 90)
Query Neighborhood Hits	230	Target Neighborhood Hits	103	Shared Neighborhood Hits	96
SwissProt Accessions	P48281	Gene names	Vdr, Nr1i1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

PXR_HUMAN
NC score	0.899256 (rank : 81)	θ value	1.05554e-24 (rank : 66)
Query Neighborhood Hits	230	Target Neighborhood Hits	107	Shared Neighborhood Hits	97
SwissProt Accessions	O75469, Q96AC7, Q9UJ22, Q9UJ23, Q9UJ24, Q9UJ25, Q9UJ26, Q9UJ27	Gene names	NR1I2, PXR
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor) (Orphan nuclear receptor PAR1) (Steroid and xenobiotic receptor) (SXR).

RORB_MOUSE
NC score	0.899205 (rank : 82)	θ value	4.01107e-24 (rank : 72)
Query Neighborhood Hits	230	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	Q8R1B8	Gene names	Rorb, Nr1f2
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORA_HUMAN
NC score	0.899205 (rank : 83)	θ value	4.73814e-25 (rank : 64)
Query Neighborhood Hits	230	Target Neighborhood Hits	105	Shared Neighborhood Hits	95
SwissProt Accessions	P35398, P35397, P35399, P45445, Q96H83	Gene names	RORA, NR1F1, RZRA
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

RORB_HUMAN
NC score	0.899200 (rank : 84)	θ value	4.01107e-24 (rank : 71)
Query Neighborhood Hits	230	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	Q92753, Q8WX73	Gene names	RORB, NR1F2, RZRB
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORA_MOUSE
NC score	0.898575 (rank : 85)	θ value	4.73814e-25 (rank : 65)
Query Neighborhood Hits	230	Target Neighborhood Hits	105	Shared Neighborhood Hits	95
SwissProt Accessions	P51448, P70283, P97741, P97773, Q923G1	Gene names	Rora, Nr1f1, Rzra
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

RORG_HUMAN
NC score	0.897901 (rank : 86)	θ value	4.01107e-24 (rank : 73)
Query Neighborhood Hits	230	Target Neighborhood Hits	119	Shared Neighborhood Hits	96
SwissProt Accessions	P51449, Q8N5V7, Q8NCY8	Gene names	RORC, NR1F3, RORG, RZRG
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma).

ANDR_MOUSE
NC score	0.883179 (rank : 87)	θ value	1.92365e-26 (rank : 62)
Query Neighborhood Hits	230	Target Neighborhood Hits	133	Shared Neighborhood Hits	102
SwissProt Accessions	P19091	Gene names	Ar, Nr3c4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

GCR_HUMAN
NC score	0.883131 (rank : 88)	θ value	1.16704e-23 (rank : 76)
Query Neighborhood Hits	230	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P04150, P04151, Q53EP5, Q6N0A4	Gene names	NR3C1, GRL
Domain Architecture
Description	Glucocorticoid receptor (GR).

ANDR_HUMAN
NC score	0.880271 (rank : 89)	θ value	6.84181e-24 (rank : 74)
Query Neighborhood Hits	230	Target Neighborhood Hits	126	Shared Neighborhood Hits	99
SwissProt Accessions	P10275	Gene names	AR, DHTR, NR3C4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

GCR_MOUSE
NC score	0.877422 (rank : 90)	θ value	1.29031e-22 (rank : 78)
Query Neighborhood Hits	230	Target Neighborhood Hits	117	Shared Neighborhood Hits	96
SwissProt Accessions	P06537, Q61628, Q61629	Gene names	Nr3c1, Grl, Grl1
Domain Architecture
Description	Glucocorticoid receptor (GR).

MCR_HUMAN
NC score	0.876857 (rank : 91)	θ value	1.5242e-23 (rank : 77)
Query Neighborhood Hits	230	Target Neighborhood Hits	149	Shared Neighborhood Hits	104
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

MCR_MOUSE
NC score	0.872182 (rank : 92)	θ value	1.5773e-20 (rank : 87)
Query Neighborhood Hits	230	Target Neighborhood Hits	162	Shared Neighborhood Hits	104
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

PRGR_HUMAN
NC score	0.871935 (rank : 93)	θ value	8.95645e-16 (rank : 94)
Query Neighborhood Hits	230	Target Neighborhood Hits	163	Shared Neighborhood Hits	106
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

PRGR_MOUSE
NC score	0.867586 (rank : 94)	θ value	4.15078e-21 (rank : 86)
Query Neighborhood Hits	230	Target Neighborhood Hits	286	Shared Neighborhood Hits	115
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

SHP_HUMAN
NC score	0.603222 (rank : 95)	θ value	3.89403e-11 (rank : 95)
Query Neighborhood Hits	230	Target Neighborhood Hits	57	Shared Neighborhood Hits	56
SwissProt Accessions	Q15466, Q5QP36	Gene names	NR0B2, SHP
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

SHP_MOUSE
NC score	0.594275 (rank : 96)	θ value	1.9326e-10 (rank : 97)
Query Neighborhood Hits	230	Target Neighborhood Hits	53	Shared Neighborhood Hits	53
SwissProt Accessions	Q62227, Q53Z53	Gene names	Nr0b2, Shp
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

DAX1_MOUSE
NC score	0.584387 (rank : 97)	θ value	1.133e-10 (rank : 96)
Query Neighborhood Hits	230	Target Neighborhood Hits	70	Shared Neighborhood Hits	60
SwissProt Accessions	Q61066, O09068, O09147	Gene names	Nr0b1, Ahch, Dax1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1).

DAX1_HUMAN
NC score	0.561957 (rank : 98)	θ value	2.52405e-10 (rank : 98)
Query Neighborhood Hits	230	Target Neighborhood Hits	65	Shared Neighborhood Hits	59
SwissProt Accessions	P51843, Q96F69	Gene names	NR0B1, AHC, DAX1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1) (DSS-AHC critical region on the X chromosome protein 1).

BCL9_MOUSE
NC score	0.053802 (rank : 99)	θ value	0.21417 (rank : 117)
Query Neighborhood Hits	230	Target Neighborhood Hits	770	Shared Neighborhood Hits	82
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

NCOA6_MOUSE
NC score	0.045865 (rank : 100)	θ value	0.0252991 (rank : 105)
Query Neighborhood Hits	230	Target Neighborhood Hits	1076	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NCOA6_HUMAN
NC score	0.044415 (rank : 101)	θ value	0.0113563 (rank : 103)
Query Neighborhood Hits	230	Target Neighborhood Hits	1202	Shared Neighborhood Hits	86
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

BCL9_HUMAN
NC score	0.044003 (rank : 102)	θ value	0.47712 (rank : 122)
Query Neighborhood Hits	230	Target Neighborhood Hits	1008	Shared Neighborhood Hits	84
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BAT2_HUMAN
NC score	0.038000 (rank : 103)	θ value	0.365318 (rank : 120)
Query Neighborhood Hits	230	Target Neighborhood Hits	931	Shared Neighborhood Hits	83
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

EP300_HUMAN
NC score	0.037692 (rank : 104)	θ value	8.99809 (rank : 219)
Query Neighborhood Hits	230	Target Neighborhood Hits	821	Shared Neighborhood Hits	81
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

MISS_MOUSE
NC score	0.035442 (rank : 105)	θ value	0.62314 (rank : 130)
Query Neighborhood Hits	230	Target Neighborhood Hits	444	Shared Neighborhood Hits	51
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

BAT2_MOUSE
NC score	0.035359 (rank : 106)	θ value	0.365318 (rank : 121)
Query Neighborhood Hits	230	Target Neighborhood Hits	947	Shared Neighborhood Hits	79
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CBP_MOUSE
NC score	0.032394 (rank : 107)	θ value	0.62314 (rank : 125)
Query Neighborhood Hits	230	Target Neighborhood Hits	1051	Shared Neighborhood Hits	79
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

RGS3_MOUSE
NC score	0.030891 (rank : 108)	θ value	0.000270298 (rank : 99)
Query Neighborhood Hits	230	Target Neighborhood Hits	1621	Shared Neighborhood Hits	76
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CBP_HUMAN
NC score	0.030682 (rank : 109)	θ value	4.03905 (rank : 173)
Query Neighborhood Hits	230	Target Neighborhood Hits	941	Shared Neighborhood Hits	75
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

SC24C_HUMAN
NC score	0.030037 (rank : 110)	θ value	4.03905 (rank : 183)
Query Neighborhood Hits	230	Target Neighborhood Hits	662	Shared Neighborhood Hits	60
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SON_HUMAN
NC score	0.029466 (rank : 111)	θ value	0.00102713 (rank : 100)
Query Neighborhood Hits	230	Target Neighborhood Hits	1568	Shared Neighborhood Hits	82
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

NACAM_MOUSE
NC score	0.029239 (rank : 112)	θ value	0.0736092 (rank : 110)
Query Neighborhood Hits	230	Target Neighborhood Hits	1866	Shared Neighborhood Hits	89
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

OGFR_HUMAN
NC score	0.027750 (rank : 113)	θ value	0.0961366 (rank : 112)
Query Neighborhood Hits	230	Target Neighborhood Hits	1582	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SPT5H_HUMAN
NC score	0.027576 (rank : 114)	θ value	0.163984 (rank : 114)
Query Neighborhood Hits	230	Target Neighborhood Hits	436	Shared Neighborhood Hits	45
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
NC score	0.027537 (rank : 115)	θ value	0.163984 (rank : 115)
Query Neighborhood Hits	230	Target Neighborhood Hits	437	Shared Neighborhood Hits	45
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

PRRT3_HUMAN
NC score	0.027085 (rank : 116)	θ value	0.125558 (rank : 113)
Query Neighborhood Hits	230	Target Neighborhood Hits	998	Shared Neighborhood Hits	63
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PELP1_MOUSE
NC score	0.026959 (rank : 117)	θ value	3.0926 (rank : 169)
Query Neighborhood Hits	230	Target Neighborhood Hits	709	Shared Neighborhood Hits	71
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

MLL3_HUMAN
NC score	0.026238 (rank : 118)	θ value	0.0563607 (rank : 109)
Query Neighborhood Hits	230	Target Neighborhood Hits	1644	Shared Neighborhood Hits	87
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MAGE1_HUMAN
NC score	0.026176 (rank : 119)	θ value	0.0961366 (rank : 111)
Query Neighborhood Hits	230	Target Neighborhood Hits	1389	Shared Neighborhood Hits	81
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

ARI1A_HUMAN
NC score	0.025576 (rank : 120)	θ value	6.88961 (rank : 198)
Query Neighborhood Hits	230	Target Neighborhood Hits	787	Shared Neighborhood Hits	81
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

NRX2B_HUMAN
NC score	0.025253 (rank : 121)	θ value	0.0252991 (rank : 107)
Query Neighborhood Hits	230	Target Neighborhood Hits	481	Shared Neighborhood Hits	33
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

ZIM10_HUMAN
NC score	0.025146 (rank : 122)	θ value	1.38821 (rank : 147)
Query Neighborhood Hits	230	Target Neighborhood Hits	577	Shared Neighborhood Hits	58
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZIM10_MOUSE
NC score	0.024376 (rank : 123)	θ value	1.81305 (rank : 152)
Query Neighborhood Hits	230	Target Neighborhood Hits	430	Shared Neighborhood Hits	54
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

MLL2_HUMAN
NC score	0.024314 (rank : 124)	θ value	1.38821 (rank : 141)
Query Neighborhood Hits	230	Target Neighborhood Hits	1788	Shared Neighborhood Hits	98
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PI5PA_HUMAN
NC score	0.023983 (rank : 125)	θ value	4.03905 (rank : 180)
Query Neighborhood Hits	230	Target Neighborhood Hits	749	Shared Neighborhood Hits	73
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

CRTC1_HUMAN
NC score	0.023333 (rank : 126)	θ value	6.88961 (rank : 199)
Query Neighborhood Hits	230	Target Neighborhood Hits	319	Shared Neighborhood Hits	52
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

RGS3_HUMAN
NC score	0.022038 (rank : 127)	θ value	0.00390308 (rank : 101)
Query Neighborhood Hits	230	Target Neighborhood Hits	1375	Shared Neighborhood Hits	59
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

CECR2_HUMAN
NC score	0.021968 (rank : 128)	θ value	0.0113563 (rank : 102)
Query Neighborhood Hits	230	Target Neighborhood Hits	543	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CEL_HUMAN
NC score	0.021113 (rank : 129)	θ value	0.0330416 (rank : 108)
Query Neighborhood Hits	230	Target Neighborhood Hits	896	Shared Neighborhood Hits	51
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

TS13_MOUSE
NC score	0.021068 (rank : 130)	θ value	1.06291 (rank : 139)
Query Neighborhood Hits	230	Target Neighborhood Hits	191	Shared Neighborhood Hits	14
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

TCGAP_HUMAN
NC score	0.020317 (rank : 131)	θ value	0.163984 (rank : 116)
Query Neighborhood Hits	230	Target Neighborhood Hits	872	Shared Neighborhood Hits	68
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

MLL3_MOUSE
NC score	0.019896 (rank : 132)	θ value	2.36792 (rank : 155)
Query Neighborhood Hits	230	Target Neighborhood Hits	1399	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

S23IP_MOUSE
NC score	0.019885 (rank : 133)	θ value	4.03905 (rank : 182)
Query Neighborhood Hits	230	Target Neighborhood Hits	363	Shared Neighborhood Hits	46
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

MILK1_MOUSE
NC score	0.019840 (rank : 134)	θ value	0.279714 (rank : 118)
Query Neighborhood Hits	230	Target Neighborhood Hits	788	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MKL1_MOUSE
NC score	0.019686 (rank : 135)	θ value	2.36792 (rank : 154)
Query Neighborhood Hits	230	Target Neighborhood Hits	667	Shared Neighborhood Hits	50
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

PER3_HUMAN
NC score	0.019533 (rank : 136)	θ value	2.36792 (rank : 158)
Query Neighborhood Hits	230	Target Neighborhood Hits	479	Shared Neighborhood Hits	47
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

MUCDL_HUMAN
NC score	0.018992 (rank : 137)	θ value	1.38821 (rank : 142)
Query Neighborhood Hits	230	Target Neighborhood Hits	777	Shared Neighborhood Hits	59
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

ZIMP7_MOUSE
NC score	0.018929 (rank : 138)	θ value	5.27518 (rank : 197)
Query Neighborhood Hits	230	Target Neighborhood Hits	566	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

SRBP1_MOUSE
NC score	0.018746 (rank : 139)	θ value	6.88961 (rank : 207)
Query Neighborhood Hits	230	Target Neighborhood Hits	384	Shared Neighborhood Hits	42
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

CO9A1_MOUSE
NC score	0.018709 (rank : 140)	θ value	0.0148317 (rank : 104)
Query Neighborhood Hits	230	Target Neighborhood Hits	477	Shared Neighborhood Hits	48
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

DOK2_MOUSE
NC score	0.018690 (rank : 141)	θ value	0.62314 (rank : 126)
Query Neighborhood Hits	230	Target Neighborhood Hits	244	Shared Neighborhood Hits	20
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

F120C_HUMAN
NC score	0.018462 (rank : 142)	θ value	0.47712 (rank : 123)
Query Neighborhood Hits	230	Target Neighborhood Hits	91	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NX05	Gene names	FAM120C, CXorf17
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120C (Tumor antigen BJ-HCC-21).

F120C_MOUSE
NC score	0.018036 (rank : 143)	θ value	0.813845 (rank : 134)
Query Neighborhood Hits	230	Target Neighborhood Hits	98	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C3F2	Gene names	Fam120c, ORF34
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120C.

F100B_MOUSE
NC score	0.017638 (rank : 144)	θ value	1.81305 (rank : 148)
Query Neighborhood Hits	230	Target Neighborhood Hits	91	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BQH4, Q3UMH5	Gene names	Fam100b
Domain Architecture	No domain graphic available
Description	Protein FAM100B.

PCLO_MOUSE
NC score	0.016918 (rank : 145)	θ value	0.62314 (rank : 132)
Query Neighborhood Hits	230	Target Neighborhood Hits	2275	Shared Neighborhood Hits	93
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

NRX2A_HUMAN
NC score	0.016659 (rank : 146)	θ value	0.0252991 (rank : 106)
Query Neighborhood Hits	230	Target Neighborhood Hits	614	Shared Neighborhood Hits	35
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

TENS1_HUMAN
NC score	0.016271 (rank : 147)	θ value	4.03905 (rank : 187)
Query Neighborhood Hits	230	Target Neighborhood Hits	400	Shared Neighborhood Hits	44
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

SSBP4_HUMAN
NC score	0.015955 (rank : 148)	θ value	8.99809 (rank : 229)
Query Neighborhood Hits	230	Target Neighborhood Hits	753	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

CRSP2_HUMAN
NC score	0.015737 (rank : 149)	θ value	8.99809 (rank : 217)
Query Neighborhood Hits	230	Target Neighborhood Hits	380	Shared Neighborhood Hits	45
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

CJ108_HUMAN
NC score	0.015437 (rank : 150)	θ value	2.36792 (rank : 153)
Query Neighborhood Hits	230	Target Neighborhood Hits	165	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

TPO_MOUSE
NC score	0.015189 (rank : 151)	θ value	4.03905 (rank : 188)
Query Neighborhood Hits	230	Target Neighborhood Hits	258	Shared Neighborhood Hits	22
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

TARSH_HUMAN
NC score	0.015021 (rank : 152)	θ value	4.03905 (rank : 185)
Query Neighborhood Hits	230	Target Neighborhood Hits	768	Shared Neighborhood Hits	52
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

PCLO_HUMAN
NC score	0.014434 (rank : 153)	θ value	4.03905 (rank : 179)
Query Neighborhood Hits	230	Target Neighborhood Hits	2046	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

NCOR1_HUMAN
NC score	0.014261 (rank : 154)	θ value	0.813845 (rank : 136)
Query Neighborhood Hits	230	Target Neighborhood Hits	577	Shared Neighborhood Hits	36
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

PSMF1_MOUSE
NC score	0.013983 (rank : 155)	θ value	5.27518 (rank : 195)
Query Neighborhood Hits	230	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BHL8, Q8C0G9	Gene names	Psmf1
Domain Architecture	No domain graphic available
Description	Proteasome inhibitor PI31 subunit.

NCOR1_MOUSE
NC score	0.013632 (rank : 156)	θ value	1.38821 (rank : 143)
Query Neighborhood Hits	230	Target Neighborhood Hits	521	Shared Neighborhood Hits	29
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

IF4G1_MOUSE
NC score	0.013506 (rank : 157)	θ value	4.03905 (rank : 176)
Query Neighborhood Hits	230	Target Neighborhood Hits	534	Shared Neighborhood Hits	43
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

ZN598_MOUSE
NC score	0.013441 (rank : 158)	θ value	2.36792 (rank : 161)
Query Neighborhood Hits	230	Target Neighborhood Hits	255	Shared Neighborhood Hits	20
SwissProt Accessions	Q80YR4, Q6KAT0, Q8R3S1	Gene names	Znf598, Zfp598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

MEF2B_HUMAN
NC score	0.012843 (rank : 159)	θ value	5.27518 (rank : 193)
Query Neighborhood Hits	230	Target Neighborhood Hits	150	Shared Neighborhood Hits	24
SwissProt Accessions	Q02080	Gene names	MEF2B, XMEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2B (Serum response factor-like protein 2) (XMEF2) (RSRFR2).

MMAC_HUMAN
NC score	0.012821 (rank : 160)	θ value	3.0926 (rank : 166)
Query Neighborhood Hits	230	Target Neighborhood Hits	76	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y4U1, Q5T157, Q9BRQ7	Gene names	MMACHC
Domain Architecture	No domain graphic available
Description	Methylmalonic aciduria and homocystinuria type C protein.

SAPS1_HUMAN
NC score	0.012809 (rank : 161)	θ value	6.88961 (rank : 205)
Query Neighborhood Hits	230	Target Neighborhood Hits	704	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

CN037_MOUSE
NC score	0.012097 (rank : 162)	θ value	8.99809 (rank : 214)
Query Neighborhood Hits	230	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

CO9A3_HUMAN
NC score	0.012002 (rank : 163)	θ value	8.99809 (rank : 216)
Query Neighborhood Hits	230	Target Neighborhood Hits	361	Shared Neighborhood Hits	45
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

CJ093_HUMAN
NC score	0.011691 (rank : 164)	θ value	3.0926 (rank : 162)
Query Neighborhood Hits	230	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SR76, Q86ST2, Q8N777	Gene names	C10orf93
Domain Architecture	No domain graphic available
Description	Protein C10orf93.

GNAS1_MOUSE
NC score	0.011572 (rank : 165)	θ value	6.88961 (rank : 202)
Query Neighborhood Hits	230	Target Neighborhood Hits	651	Shared Neighborhood Hits	53
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

TNR6A_HUMAN
NC score	0.011528 (rank : 166)	θ value	8.99809 (rank : 230)
Query Neighborhood Hits	230	Target Neighborhood Hits	343	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

SNPC4_MOUSE
NC score	0.011160 (rank : 167)	θ value	4.03905 (rank : 184)
Query Neighborhood Hits	230	Target Neighborhood Hits	237	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

PYGO1_MOUSE
NC score	0.011095 (rank : 168)	θ value	8.99809 (rank : 227)
Query Neighborhood Hits	230	Target Neighborhood Hits	69	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D0P5	Gene names	Pygo1
Domain Architecture
Description	Pygopus homolog 1.

ETV5_MOUSE
NC score	0.011047 (rank : 169)	θ value	1.06291 (rank : 137)
Query Neighborhood Hits	230	Target Neighborhood Hits	328	Shared Neighborhood Hits	36
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

DOK1_MOUSE
NC score	0.010682 (rank : 170)	θ value	4.03905 (rank : 174)
Query Neighborhood Hits	230	Target Neighborhood Hits	82	Shared Neighborhood Hits	9
SwissProt Accessions	P97465, Q9R213	Gene names	Dok1, Dok
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)).

RBNS5_MOUSE
NC score	0.010500 (rank : 171)	θ value	0.62314 (rank : 133)
Query Neighborhood Hits	230	Target Neighborhood Hits	266	Shared Neighborhood Hits	13
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

TCF19_HUMAN
NC score	0.010127 (rank : 172)	θ value	3.0926 (rank : 171)
Query Neighborhood Hits	230	Target Neighborhood Hits	124	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y242, Q13176, Q15967, Q5SQ89, Q5STD6, Q5STF5, Q9BUM2, Q9UBH7	Gene names	TCF19, SC1
Domain Architecture
Description	Transcription factor 19 (Transcription factor SC1).

PAX1_MOUSE
NC score	0.009997 (rank : 173)	θ value	6.88961 (rank : 204)
Query Neighborhood Hits	230	Target Neighborhood Hits	69	Shared Neighborhood Hits	10
SwissProt Accessions	P09084, Q9R2B1	Gene names	Pax1, Pax-1
Domain Architecture
Description	Paired box protein Pax-1.

JPH2_HUMAN
NC score	0.009965 (rank : 174)	θ value	5.27518 (rank : 192)
Query Neighborhood Hits	230	Target Neighborhood Hits	639	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

TLE1_MOUSE
NC score	0.009955 (rank : 175)	θ value	1.38821 (rank : 146)
Query Neighborhood Hits	230	Target Neighborhood Hits	491	Shared Neighborhood Hits	31
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

RP1L1_HUMAN
NC score	0.009894 (rank : 176)	θ value	3.0926 (rank : 170)
Query Neighborhood Hits	230	Target Neighborhood Hits	1072	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

PIGQ_HUMAN
NC score	0.009739 (rank : 177)	θ value	1.81305 (rank : 149)
Query Neighborhood Hits	230	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BRB3, O14927, Q96G00, Q96S22, Q9UJH4	Gene names	PIGQ, GPI1
Domain Architecture
Description	Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (EC 2.4.1.198) (Phosphatidylinositol-glycan biosynthesis class Q protein) (PIG-Q) (N-acetylglucosamyl transferase component GPI1).

CUTC_HUMAN
NC score	0.009644 (rank : 178)	θ value	5.27518 (rank : 189)
Query Neighborhood Hits	230	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NTM9, Q9Y321	Gene names	CUTC
Domain Architecture	No domain graphic available
Description	Copper homeostasis protein cutC homolog.

TLE4_MOUSE
NC score	0.009404 (rank : 179)	θ value	6.88961 (rank : 211)
Query Neighborhood Hits	230	Target Neighborhood Hits	482	Shared Neighborhood Hits	30
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

TLE4_HUMAN
NC score	0.009231 (rank : 180)	θ value	6.88961 (rank : 210)
Query Neighborhood Hits	230	Target Neighborhood Hits	477	Shared Neighborhood Hits	29
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

MYO15_HUMAN
NC score	0.009085 (rank : 181)	θ value	0.813845 (rank : 135)
Query Neighborhood Hits	230	Target Neighborhood Hits	671	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PAX5_MOUSE
NC score	0.008954 (rank : 182)	θ value	2.36792 (rank : 157)
Query Neighborhood Hits	230	Target Neighborhood Hits	106	Shared Neighborhood Hits	10
SwissProt Accessions	Q02650	Gene names	Pax5, Pax-5
Domain Architecture
Description	Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP).

PAX5_HUMAN
NC score	0.008950 (rank : 183)	θ value	2.36792 (rank : 156)
Query Neighborhood Hits	230	Target Neighborhood Hits	106	Shared Neighborhood Hits	10
SwissProt Accessions	Q02548, O75933	Gene names	PAX5
Domain Architecture
Description	Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP).

TLE1_HUMAN
NC score	0.008723 (rank : 184)	θ value	1.06291 (rank : 138)
Query Neighborhood Hits	230	Target Neighborhood Hits	485	Shared Neighborhood Hits	31
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

MAP1A_HUMAN
NC score	0.008718 (rank : 185)	θ value	0.62314 (rank : 129)
Query Neighborhood Hits	230	Target Neighborhood Hits	1626	Shared Neighborhood Hits	58
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

K1802_MOUSE
NC score	0.008429 (rank : 186)	θ value	4.03905 (rank : 177)
Query Neighborhood Hits	230	Target Neighborhood Hits	1596	Shared Neighborhood Hits	71
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

HELZ_HUMAN
NC score	0.008341 (rank : 187)	θ value	3.0926 (rank : 164)
Query Neighborhood Hits	230	Target Neighborhood Hits	198	Shared Neighborhood Hits	20
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

SOX30_MOUSE
NC score	0.007982 (rank : 188)	θ value	2.36792 (rank : 160)
Query Neighborhood Hits	230	Target Neighborhood Hits	374	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

IASPP_MOUSE
NC score	0.007957 (rank : 189)	θ value	0.62314 (rank : 128)
Query Neighborhood Hits	230	Target Neighborhood Hits	1024	Shared Neighborhood Hits	53
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

PYGO1_HUMAN
NC score	0.007748 (rank : 190)	θ value	8.99809 (rank : 226)
Query Neighborhood Hits	230	Target Neighborhood Hits	90	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y3Y4	Gene names	PYGO1
Domain Architecture
Description	Pygopus homolog 1.

JIP2_HUMAN
NC score	0.007344 (rank : 191)	θ value	6.88961 (rank : 203)
Query Neighborhood Hits	230	Target Neighborhood Hits	288	Shared Neighborhood Hits	21
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

PKD1_HUMAN
NC score	0.007077 (rank : 192)	θ value	1.81305 (rank : 150)
Query Neighborhood Hits	230	Target Neighborhood Hits	387	Shared Neighborhood Hits	6
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

MEGF9_MOUSE
NC score	0.006977 (rank : 193)	θ value	8.99809 (rank : 224)
Query Neighborhood Hits	230	Target Neighborhood Hits	896	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

LRC50_HUMAN
NC score	0.006229 (rank : 194)	θ value	8.99809 (rank : 223)
Query Neighborhood Hits	230	Target Neighborhood Hits	275	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NEP3, Q69YI8, Q69YJ0, Q96LP3	Gene names	LRRC50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

NFH_MOUSE
NC score	0.005696 (rank : 195)	θ value	5.27518 (rank : 194)
Query Neighborhood Hits	230	Target Neighborhood Hits	2247	Shared Neighborhood Hits	74
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MYO15_MOUSE
NC score	0.005619 (rank : 196)	θ value	3.0926 (rank : 167)
Query Neighborhood Hits	230	Target Neighborhood Hits	467	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

FXL19_MOUSE
NC score	0.005474 (rank : 197)	θ value	5.27518 (rank : 190)
Query Neighborhood Hits	230	Target Neighborhood Hits	217	Shared Neighborhood Hits	19
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

FOXP4_MOUSE
NC score	0.005319 (rank : 198)	θ value	1.38821 (rank : 140)
Query Neighborhood Hits	230	Target Neighborhood Hits	211	Shared Neighborhood Hits	16
SwissProt Accessions	Q9DBY0, Q80V92, Q8CG10, Q8CIS1	Gene names	Foxp4
Domain Architecture	No domain graphic available
Description	Forkhead box protein P4 (Fork head-related protein like A) (mFKHLA).

FREA_HUMAN
NC score	0.005318 (rank : 199)	θ value	0.62314 (rank : 127)
Query Neighborhood Hits	230	Target Neighborhood Hits	205	Shared Neighborhood Hits	17
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

CTND2_HUMAN
NC score	0.005224 (rank : 200)	θ value	8.99809 (rank : 218)
Query Neighborhood Hits	230	Target Neighborhood Hits	333	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

GP123_HUMAN
NC score	0.005160 (rank : 201)	θ value	4.03905 (rank : 175)
Query Neighborhood Hits	230	Target Neighborhood Hits	120	Shared Neighborhood Hits	5
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

ETV3_HUMAN
NC score	0.005070 (rank : 202)	θ value	6.88961 (rank : 200)
Query Neighborhood Hits	230	Target Neighborhood Hits	312	Shared Neighborhood Hits	23
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

FOXP4_HUMAN
NC score	0.004837 (rank : 203)	θ value	6.88961 (rank : 201)
Query Neighborhood Hits	230	Target Neighborhood Hits	246	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IVH2, Q96E19	Gene names	FOXP4, FKHLA
Domain Architecture
Description	Forkhead box protein P4 (Fork head-related protein-like A).

PDZD2_HUMAN
NC score	0.004427 (rank : 204)	θ value	3.0926 (rank : 168)
Query Neighborhood Hits	230	Target Neighborhood Hits	772	Shared Neighborhood Hits	39
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

TCF7_MOUSE
NC score	0.003302 (rank : 205)	θ value	4.03905 (rank : 186)
Query Neighborhood Hits	230	Target Neighborhood Hits	277	Shared Neighborhood Hits	19
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

CAC1G_HUMAN
NC score	0.003024 (rank : 206)	θ value	8.99809 (rank : 213)
Query Neighborhood Hits	230	Target Neighborhood Hits	587	Shared Neighborhood Hits	37
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

ATS7_HUMAN
NC score	0.002992 (rank : 207)	θ value	8.99809 (rank : 212)
Query Neighborhood Hits	230	Target Neighborhood Hits	169	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

RFFL_HUMAN
NC score	0.002968 (rank : 208)	θ value	8.99809 (rank : 228)
Query Neighborhood Hits	230	Target Neighborhood Hits	175	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

ZN687_HUMAN
NC score	0.002399 (rank : 209)	θ value	0.279714 (rank : 119)
Query Neighborhood Hits	230	Target Neighborhood Hits	1244	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

PAX7_HUMAN
NC score	0.002288 (rank : 210)	θ value	0.62314 (rank : 131)
Query Neighborhood Hits	230	Target Neighborhood Hits	456	Shared Neighborhood Hits	11
SwissProt Accessions	P23759	Gene names	PAX7, HUP1
Domain Architecture
Description	Paired box protein Pax-7 (HUP1).

LAMC2_HUMAN
NC score	0.001609 (rank : 211)	θ value	3.0926 (rank : 165)
Query Neighborhood Hits	230	Target Neighborhood Hits	715	Shared Neighborhood Hits	19
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

SCUB3_HUMAN
NC score	0.001301 (rank : 212)	θ value	1.81305 (rank : 151)
Query Neighborhood Hits	230	Target Neighborhood Hits	428	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

IRF3_HUMAN
NC score	0.001159 (rank : 213)	θ value	8.99809 (rank : 222)
Query Neighborhood Hits	230	Target Neighborhood Hits	129	Shared Neighborhood Hits	7
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

SCUB3_MOUSE
NC score	0.000954 (rank : 214)	θ value	2.36792 (rank : 159)
Query Neighborhood Hits	230	Target Neighborhood Hits	442	Shared Neighborhood Hits	10
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

PINC_HUMAN
NC score	0.000573 (rank : 215)	θ value	4.03905 (rank : 181)
Query Neighborhood Hits	230	Target Neighborhood Hits	231	Shared Neighborhood Hits	3
SwissProt Accessions	P48059, Q53TE0, Q9BS44	Gene names	LIMS1
Domain Architecture
Description	Protein PINCH (Particularly interesting new Cys-His protein) (LIM and senescent cell antigen-like domains 1) (NY-REN-48 antigen).

SEM6B_MOUSE
NC score	-0.000599 (rank : 216)	θ value	6.88961 (rank : 206)
Query Neighborhood Hits	230	Target Neighborhood Hits	200	Shared Neighborhood Hits	8
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

CNTRB_MOUSE
NC score	-0.001275 (rank : 217)	θ value	8.99809 (rank : 215)
Query Neighborhood Hits	230	Target Neighborhood Hits	1029	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

NOTC3_HUMAN
NC score	-0.001931 (rank : 218)	θ value	1.38821 (rank : 144)
Query Neighborhood Hits	230	Target Neighborhood Hits	1062	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

TENX_HUMAN
NC score	-0.002590 (rank : 219)	θ value	6.88961 (rank : 208)
Query Neighborhood Hits	230	Target Neighborhood Hits	789	Shared Neighborhood Hits	19
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

SLIT3_HUMAN
NC score	-0.003898 (rank : 220)	θ value	5.27518 (rank : 196)
Query Neighborhood Hits	230	Target Neighborhood Hits	682	Shared Neighborhood Hits	12
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

GSH2_MOUSE
NC score	-0.004549 (rank : 221)	θ value	8.99809 (rank : 221)
Query Neighborhood Hits	230	Target Neighborhood Hits	319	Shared Neighborhood Hits	3
SwissProt Accessions	P31316	Gene names	Gsh2, Gsh-2
Domain Architecture
Description	Homeobox protein GSH-2.

GLI2_HUMAN
NC score	-0.005046 (rank : 222)	θ value	5.27518 (rank : 191)
Query Neighborhood Hits	230	Target Neighborhood Hits	971	Shared Neighborhood Hits	36
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

ZBTB3_HUMAN
NC score	-0.005201 (rank : 223)	θ value	3.0926 (rank : 172)
Query Neighborhood Hits	230	Target Neighborhood Hits	910	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

MAST4_HUMAN
NC score	-0.005421 (rank : 224)	θ value	0.47712 (rank : 124)
Query Neighborhood Hits	230	Target Neighborhood Hits	1804	Shared Neighborhood Hits	53
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

EDNRB_MOUSE
NC score	-0.006034 (rank : 225)	θ value	3.0926 (rank : 163)
Query Neighborhood Hits	230	Target Neighborhood Hits	587	Shared Neighborhood Hits	2
SwissProt Accessions	P48302, Q542M3	Gene names	Ednrb
Domain Architecture
Description	Endothelin B receptor precursor (ET-B) (Endothelin receptor Non- selective type).

GLIS3_MOUSE
NC score	-0.007257 (rank : 226)	θ value	8.99809 (rank : 220)
Query Neighborhood Hits	230	Target Neighborhood Hits	861	Shared Neighborhood Hits	31
SwissProt Accessions	Q6XP49, Q8BI60	Gene names	Glis3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3).

LTK_MOUSE
NC score	-0.007345 (rank : 227)	θ value	4.03905 (rank : 178)
Query Neighborhood Hits	230	Target Neighborhood Hits	770	Shared Neighborhood Hits	6
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

PATZ1_HUMAN
NC score	-0.007569 (rank : 228)	θ value	1.38821 (rank : 145)
Query Neighborhood Hits	230	Target Neighborhood Hits	802	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HBE1, Q9HBE2, Q9HBE3, Q9P1A9, Q9UDU0, Q9Y529	Gene names	PATZ1, PATZ, RIAZ, ZBTB19, ZNF278, ZSG
Domain Architecture
Description	POZ-, AT hook-, and zinc finger-containing protein 1 (Zinc finger protein 278) (Zinc finger sarcoma gene protein) (BTB-POZ domain zinc finger transcription factor) (Protein kinase A RI-subunit alpha- associated protein) (Zinc finger and BTB domain-containing protein 19).

TIE1_MOUSE
NC score	-0.009588 (rank : 229)	θ value	6.88961 (rank : 209)
Query Neighborhood Hits	230	Target Neighborhood Hits	1266	Shared Neighborhood Hits	13
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

NEK6_MOUSE
NC score	-0.009998 (rank : 230)	θ value	8.99809 (rank : 225)
Query Neighborhood Hits	230	Target Neighborhood Hits	851	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ES70, Q3TCE9, Q8C6E6, Q9D0E2, Q9DBI8	Gene names	Nek6
Domain Architecture
Description	Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (NimA-related protein kinase 6).