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Network neighborhood for query Sequence : STF1_HUMAN

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STF1_HUMAN
SwissProt Accessions	Q13285, O15196	Gene names	NR5A1, AD4BP, FTZF1, SF1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

STF1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	132	Target Neighborhood Hits	132	Shared Neighborhood Hits	132
SwissProt Accessions	Q13285, O15196	Gene names	NR5A1, AD4BP, FTZF1, SF1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1).

STF1_MOUSE
θ value	0 (rank : 2)	NC score	0.996868 (rank : 2)
Query Neighborhood Hits	132	Target Neighborhood Hits	137	Shared Neighborhood Hits	107
SwissProt Accessions	P33242	Gene names	Nr5a1, Ftzf1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1) (Embryonal LTR-binding protein) (ELP) (Embryonal long terminal repeat- binding protein) (Steroid hydroxylase positive regulator).

NR5A2_HUMAN
θ value	1.91371e-159 (rank : 3)	NC score	0.991007 (rank : 3)
Query Neighborhood Hits	132	Target Neighborhood Hits	112	Shared Neighborhood Hits	99
SwissProt Accessions	O00482, O95642	Gene names	NR5A2, B1F, CPF, FTF
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Alpha-1-fetoprotein transcription factor) (Hepatocytic transcription factor) (B1-binding factor) (hB1F) (CYP7A promoter-binding factor) (Liver receptor homolog 1) (LRH-1).

NR5A2_MOUSE
θ value	5.05951e-144 (rank : 4)	NC score	0.990750 (rank : 4)
Query Neighborhood Hits	132	Target Neighborhood Hits	107	Shared Neighborhood Hits	98
SwissProt Accessions	P45448	Gene names	Nr5a2, Lrh1
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Liver receptor homolog 1) (LRH-1).

NR6A1_MOUSE
θ value	3.86705e-35 (rank : 5)	NC score	0.947187 (rank : 5)
Query Neighborhood Hits	132	Target Neighborhood Hits	110	Shared Neighborhood Hits	98
SwissProt Accessions	Q64249	Gene names	Nr6a1, Gcnf
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

ERR2_MOUSE
θ value	6.61148e-27 (rank : 6)	NC score	0.925224 (rank : 9)
Query Neighborhood Hits	132	Target Neighborhood Hits	109	Shared Neighborhood Hits	98
SwissProt Accessions	Q61539, O09067, O09146	Gene names	Esrrb, Err-2, Err2, Nr3b2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2).

ERR2_HUMAN
θ value	8.63488e-27 (rank : 7)	NC score	0.925547 (rank : 8)
Query Neighborhood Hits	132	Target Neighborhood Hits	108	Shared Neighborhood Hits	98
SwissProt Accessions	O95718, Q9HCB4	Gene names	ESRRB, ERRB2, NR3B2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2) (ERR beta-2).

ERR3_HUMAN
θ value	1.47289e-26 (rank : 8)	NC score	0.924264 (rank : 12)
Query Neighborhood Hits	132	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P62508, O75454, O96021, Q68DA0, Q6P274, Q6PK28, Q6TS38, Q9R1F3, Q9UNJ4	Gene names	ESRRG, ERR3, ERRG2, KIAA0832, NR3B3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (ERR gamma-2).

ERR3_MOUSE
θ value	1.47289e-26 (rank : 9)	NC score	0.924264 (rank : 13)
Query Neighborhood Hits	132	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P62509, O75454, O96021, Q8CHC9, Q9R1F3	Gene names	Esrrg, Err3, Kiaa0832, Nr3b3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3).

ERR1_HUMAN
θ value	5.59698e-26 (rank : 10)	NC score	0.929223 (rank : 7)
Query Neighborhood Hits	132	Target Neighborhood Hits	157	Shared Neighborhood Hits	99
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

RXRA_HUMAN
θ value	8.08199e-25 (rank : 11)	NC score	0.919612 (rank : 24)
Query Neighborhood Hits	132	Target Neighborhood Hits	223	Shared Neighborhood Hits	99
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

RXRA_MOUSE
θ value	8.08199e-25 (rank : 12)	NC score	0.922643 (rank : 17)
Query Neighborhood Hits	132	Target Neighborhood Hits	129	Shared Neighborhood Hits	101
SwissProt Accessions	P28700	Gene names	Rxra, Nr2b1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

NR4A1_HUMAN
θ value	1.05554e-24 (rank : 13)	NC score	0.923178 (rank : 15)
Query Neighborhood Hits	132	Target Neighborhood Hits	133	Shared Neighborhood Hits	96
SwissProt Accessions	P22736	Gene names	NR4A1, GFRP1, HMR, NAK1
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Early response protein NAK1) (TR3 orphan receptor) (ST-59).

NR4A2_HUMAN
θ value	1.05554e-24 (rank : 14)	NC score	0.922009 (rank : 20)
Query Neighborhood Hits	132	Target Neighborhood Hits	120	Shared Neighborhood Hits	95
SwissProt Accessions	P43354, Q16311	Gene names	NR4A2, NOT, NURR1, TINUR
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (Immediate-early response protein NOT) (Transcriptionally-inducible nuclear receptor).

NR4A2_MOUSE
θ value	1.05554e-24 (rank : 15)	NC score	0.921981 (rank : 21)
Query Neighborhood Hits	132	Target Neighborhood Hits	121	Shared Neighborhood Hits	95
SwissProt Accessions	Q06219, O08690	Gene names	Nr4a2, Nurr1
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (NUR- related factor 1).

NR4A3_HUMAN
θ value	1.37858e-24 (rank : 16)	NC score	0.925027 (rank : 10)
Query Neighborhood Hits	132	Target Neighborhood Hits	131	Shared Neighborhood Hits	96
SwissProt Accessions	Q92570, Q12935, Q14979, Q16420, Q4VXA9, Q9UEK2, Q9UEK3	Gene names	NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1) (Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphan receptor).

NR4A3_MOUSE
θ value	1.37858e-24 (rank : 17)	NC score	0.924431 (rank : 11)
Query Neighborhood Hits	132	Target Neighborhood Hits	127	Shared Neighborhood Hits	96
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

RXRB_HUMAN
θ value	2.35151e-24 (rank : 18)	NC score	0.916273 (rank : 34)
Query Neighborhood Hits	132	Target Neighborhood Hits	280	Shared Neighborhood Hits	107
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

RXRB_MOUSE
θ value	2.35151e-24 (rank : 19)	NC score	0.918745 (rank : 26)
Query Neighborhood Hits	132	Target Neighborhood Hits	230	Shared Neighborhood Hits	107
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

NR4A1_MOUSE
θ value	4.01107e-24 (rank : 20)	NC score	0.923249 (rank : 14)
Query Neighborhood Hits	132	Target Neighborhood Hits	128	Shared Neighborhood Hits	95
SwissProt Accessions	P12813	Gene names	Nr4a1, Gfrp, Hmr, N10, Nur77
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Nuclear hormone receptor NUR/77) (N10 nuclear protein).

RXRG_HUMAN
θ value	6.84181e-24 (rank : 21)	NC score	0.922257 (rank : 18)
Query Neighborhood Hits	132	Target Neighborhood Hits	114	Shared Neighborhood Hits	98
SwissProt Accessions	P48443	Gene names	RXRG, NR2B3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

RXRG_MOUSE
θ value	6.84181e-24 (rank : 22)	NC score	0.922732 (rank : 16)
Query Neighborhood Hits	132	Target Neighborhood Hits	113	Shared Neighborhood Hits	98
SwissProt Accessions	P28705	Gene names	Rxrg, Nr2b3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

RORB_HUMAN
θ value	8.93572e-24 (rank : 23)	NC score	0.917099 (rank : 30)
Query Neighborhood Hits	132	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	Q92753, Q8WX73	Gene names	RORB, NR1F2, RZRB
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORB_MOUSE
θ value	8.93572e-24 (rank : 24)	NC score	0.917394 (rank : 28)
Query Neighborhood Hits	132	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	Q8R1B8	Gene names	Rorb, Nr1f2
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

NR6A1_HUMAN
θ value	1.99067e-23 (rank : 25)	NC score	0.944446 (rank : 6)
Query Neighborhood Hits	132	Target Neighborhood Hits	108	Shared Neighborhood Hits	98
SwissProt Accessions	Q15406, O00551, O00603, Q8NHQ0, Q92898, Q99802	Gene names	NR6A1, GCNF
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

RORA_HUMAN
θ value	5.79196e-23 (rank : 26)	NC score	0.915698 (rank : 35)
Query Neighborhood Hits	132	Target Neighborhood Hits	105	Shared Neighborhood Hits	95
SwissProt Accessions	P35398, P35397, P35399, P45445, Q96H83	Gene names	RORA, NR1F1, RZRA
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

RORA_MOUSE
θ value	5.79196e-23 (rank : 27)	NC score	0.915634 (rank : 36)
Query Neighborhood Hits	132	Target Neighborhood Hits	105	Shared Neighborhood Hits	95
SwissProt Accessions	P51448, P70283, P97741, P97773, Q923G1	Gene names	Rora, Nr1f1, Rzra
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

TR4_MOUSE
θ value	5.79196e-23 (rank : 28)	NC score	0.909614 (rank : 70)
Query Neighborhood Hits	132	Target Neighborhood Hits	115	Shared Neighborhood Hits	98
SwissProt Accessions	P49117, P55093	Gene names	Nr2c2, Mtr2r1, Tak1, Tr4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

RORG_MOUSE
θ value	7.56453e-23 (rank : 29)	NC score	0.915206 (rank : 38)
Query Neighborhood Hits	132	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	P51450, Q61027, Q91YT5, Q9QXD9, Q9R177	Gene names	Rorc, Nr1f3, Rorg, Thor
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma) (Thymus orphan receptor) (TOR).

THA_HUMAN
θ value	9.87957e-23 (rank : 30)	NC score	0.910733 (rank : 67)
Query Neighborhood Hits	132	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	P10827, P21205, Q8N6A1, Q96H73	Gene names	THRA, ERBA1, NR1A1, THRA1
Domain Architecture
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1) (EAR-7) (EAR7).

THA_MOUSE
θ value	9.87957e-23 (rank : 31)	NC score	0.910741 (rank : 66)
Query Neighborhood Hits	132	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	P63058, P10685, P15827, P16416, P37241, Q63107, Q63195, Q63196, Q99146	Gene names	Thra, C-erba-alpha, Nr1a1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1).

TR4_HUMAN
θ value	1.29031e-22 (rank : 32)	NC score	0.909760 (rank : 69)
Query Neighborhood Hits	132	Target Neighborhood Hits	117	Shared Neighborhood Hits	98
SwissProt Accessions	P49116, P55092	Gene names	NR2C2, TAK1, TR4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

RORG_HUMAN
θ value	1.6852e-22 (rank : 33)	NC score	0.912090 (rank : 61)
Query Neighborhood Hits	132	Target Neighborhood Hits	119	Shared Neighborhood Hits	95
SwissProt Accessions	P51449, Q8N5V7, Q8NCY8	Gene names	RORC, NR1F3, RORG, RZRG
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma).

THB1_HUMAN
θ value	1.6852e-22 (rank : 34)	NC score	0.905093 (rank : 76)
Query Neighborhood Hits	132	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P10828, Q13986	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture
Description	Thyroid hormone receptor beta-1.

THB2_HUMAN
θ value	1.6852e-22 (rank : 35)	NC score	0.905808 (rank : 72)
Query Neighborhood Hits	132	Target Neighborhood Hits	104	Shared Neighborhood Hits	98
SwissProt Accessions	P37243	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor beta-2.

RARG1_HUMAN
θ value	4.9032e-22 (rank : 36)	NC score	0.915070 (rank : 39)
Query Neighborhood Hits	132	Target Neighborhood Hits	107	Shared Neighborhood Hits	95
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARG1_MOUSE
θ value	4.9032e-22 (rank : 37)	NC score	0.914735 (rank : 43)
Query Neighborhood Hits	132	Target Neighborhood Hits	113	Shared Neighborhood Hits	95
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

RARG2_HUMAN
θ value	4.9032e-22 (rank : 38)	NC score	0.915213 (rank : 37)
Query Neighborhood Hits	132	Target Neighborhood Hits	109	Shared Neighborhood Hits	95
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

RARG2_MOUSE
θ value	4.9032e-22 (rank : 39)	NC score	0.915025 (rank : 40)
Query Neighborhood Hits	132	Target Neighborhood Hits	114	Shared Neighborhood Hits	95
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

THB1_MOUSE
θ value	8.36355e-22 (rank : 40)	NC score	0.903992 (rank : 77)
Query Neighborhood Hits	132	Target Neighborhood Hits	105	Shared Neighborhood Hits	98
SwissProt Accessions	P37242	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-1.

THB2_MOUSE
θ value	8.36355e-22 (rank : 41)	NC score	0.903928 (rank : 78)
Query Neighborhood Hits	132	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P37244	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-2.

COT2_HUMAN
θ value	1.09232e-21 (rank : 42)	NC score	0.914042 (rank : 52)
Query Neighborhood Hits	132	Target Neighborhood Hits	135	Shared Neighborhood Hits	99
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT2_MOUSE
θ value	1.09232e-21 (rank : 43)	NC score	0.914042 (rank : 53)
Query Neighborhood Hits	132	Target Neighborhood Hits	135	Shared Neighborhood Hits	99
SwissProt Accessions	P43135	Gene names	Nr2f2, Aporp1, Arp-1, Arp1, Tfcoup2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

EAR2_MOUSE
θ value	1.09232e-21 (rank : 44)	NC score	0.916467 (rank : 33)
Query Neighborhood Hits	132	Target Neighborhood Hits	104	Shared Neighborhood Hits	98
SwissProt Accessions	P43136, Q61504	Gene names	Nr2f6, Ear-2, Ear2, Erbal2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

COT1_HUMAN
θ value	1.42661e-21 (rank : 45)	NC score	0.912644 (rank : 59)
Query Neighborhood Hits	132	Target Neighborhood Hits	159	Shared Neighborhood Hits	103
SwissProt Accessions	P10589	Gene names	NR2F1, EAR3, ERBAL3, TFCOUP1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I) (V-ERBA-related protein EAR-3).

COT1_MOUSE
θ value	1.42661e-21 (rank : 46)	NC score	0.912876 (rank : 58)
Query Neighborhood Hits	132	Target Neighborhood Hits	160	Shared Neighborhood Hits	102
SwissProt Accessions	Q60632, Q61438	Gene names	Nr2f1, Erbal3, Tfcoup1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I).

RARB_HUMAN
θ value	1.86321e-21 (rank : 47)	NC score	0.914030 (rank : 54)
Query Neighborhood Hits	132	Target Neighborhood Hits	118	Shared Neighborhood Hits	94
SwissProt Accessions	P10826, P12891, Q00989, Q15298, Q9UN48	Gene names	RARB, HAP, NR1B2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta) (RAR-epsilon) (HBV-activated protein).

RARB_MOUSE
θ value	1.86321e-21 (rank : 48)	NC score	0.914044 (rank : 51)
Query Neighborhood Hits	132	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	P22605, P11417, P22604	Gene names	Rarb, Nr1b2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta).

TR2_MOUSE
θ value	1.86321e-21 (rank : 49)	NC score	0.918051 (rank : 27)
Query Neighborhood Hits	132	Target Neighborhood Hits	100	Shared Neighborhood Hits	98
SwissProt Accessions	Q505F1, P97763, Q3UIJ7, Q4U1Z4, Q60927, Q62152, Q8VIJ3	Gene names	Nr2c1, Tr2, Tr2-11
Domain Architecture	No domain graphic available
Description	Orphan nuclear receptor TR2 (Testicular receptor 2) (mTR2).

RARA_HUMAN
θ value	2.43343e-21 (rank : 50)	NC score	0.914236 (rank : 50)
Query Neighborhood Hits	132	Target Neighborhood Hits	118	Shared Neighborhood Hits	96
SwissProt Accessions	P10276, P78456, Q13440, Q13441, Q9NQS0	Gene names	RARA, NR1B1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARA_MOUSE
θ value	2.43343e-21 (rank : 51)	NC score	0.914376 (rank : 48)
Query Neighborhood Hits	132	Target Neighborhood Hits	113	Shared Neighborhood Hits	96
SwissProt Accessions	P11416, P22603	Gene names	Rara, Nr1b1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

EAR2_HUMAN
θ value	3.17815e-21 (rank : 52)	NC score	0.916832 (rank : 32)
Query Neighborhood Hits	132	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P10588, Q9BUE8	Gene names	NR2F6, EAR2, ERBAL2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

TR2_HUMAN
θ value	3.17815e-21 (rank : 53)	NC score	0.920663 (rank : 22)
Query Neighborhood Hits	132	Target Neighborhood Hits	110	Shared Neighborhood Hits	97
SwissProt Accessions	P13056	Gene names	NR2C1, TR2
Domain Architecture
Description	Orphan nuclear receptor TR2 (Testicular receptor 2).

NR1D1_HUMAN
θ value	1.5773e-20 (rank : 54)	NC score	0.922138 (rank : 19)
Query Neighborhood Hits	132	Target Neighborhood Hits	140	Shared Neighborhood Hits	94
SwissProt Accessions	P20393, Q15304	Gene names	NR1D1, EAR1, HREV, THRAL
Domain Architecture
Description	Orphan nuclear receptor NR1D1 (V-erbA-related protein EAR-1) (Rev- erbA-alpha).

ESR1_HUMAN
θ value	4.58923e-20 (rank : 55)	NC score	0.910152 (rank : 68)
Query Neighborhood Hits	132	Target Neighborhood Hits	105	Shared Neighborhood Hits	96
SwissProt Accessions	P03372, Q13511, Q14276, Q9NU51, Q9UDZ7, Q9UIS7	Gene names	ESR1, ESR, NR3A1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

ESR1_MOUSE
θ value	4.58923e-20 (rank : 56)	NC score	0.911547 (rank : 63)
Query Neighborhood Hits	132	Target Neighborhood Hits	104	Shared Neighborhood Hits	95
SwissProt Accessions	P19785, Q9JJT5, Q9QY51, Q9QY52	Gene names	Esr1, Esr, Estr, Estra, Nr3a1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

NR1I3_HUMAN
θ value	4.58923e-20 (rank : 57)	NC score	0.920540 (rank : 23)
Query Neighborhood Hits	132	Target Neighborhood Hits	107	Shared Neighborhood Hits	99
SwissProt Accessions	Q14994	Gene names	NR1I3, CAR
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Constitutive activator of retinoid response) (Constitutive active response) (Orphan nuclear receptor MB67).

NR1D2_HUMAN
θ value	1.02238e-19 (rank : 58)	NC score	0.914690 (rank : 46)
Query Neighborhood Hits	132	Target Neighborhood Hits	115	Shared Neighborhood Hits	94
SwissProt Accessions	Q14995, O00402, Q86XD4	Gene names	NR1D2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (EAR-1R) (Orphan nuclear hormone receptor BD73).

NR2E1_MOUSE
θ value	1.02238e-19 (rank : 59)	NC score	0.917132 (rank : 29)
Query Neighborhood Hits	132	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	Q64104	Gene names	Nr2e1, Tll, Tlx
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (mTll).

PPARD_HUMAN
θ value	1.02238e-19 (rank : 60)	NC score	0.903037 (rank : 81)
Query Neighborhood Hits	132	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q03181, Q7Z5K0, Q9BUD4	Gene names	PPARD, NR1C2, PPARB
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1) (NUCI).

GCR_HUMAN
θ value	1.33526e-19 (rank : 61)	NC score	0.880441 (rank : 87)
Query Neighborhood Hits	132	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P04150, P04151, Q53EP5, Q6N0A4	Gene names	NR3C1, GRL
Domain Architecture
Description	Glucocorticoid receptor (GR).

HNF4A_HUMAN
θ value	1.33526e-19 (rank : 62)	NC score	0.914273 (rank : 49)
Query Neighborhood Hits	132	Target Neighborhood Hits	105	Shared Neighborhood Hits	98
SwissProt Accessions	P41235, O00659, O00723, Q14540, Q92653, Q92654, Q92655, Q99864, Q9NQH0	Gene names	HNF4A, HNF4, NR2A1, TCF14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

HNF4A_MOUSE
θ value	1.33526e-19 (rank : 63)	NC score	0.914719 (rank : 44)
Query Neighborhood Hits	132	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	P49698	Gene names	Hnf4a, Hnf-4, Hnf4, Nr2a1, Tcf14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

HNF4G_HUMAN
θ value	1.33526e-19 (rank : 64)	NC score	0.914698 (rank : 45)
Query Neighborhood Hits	132	Target Neighborhood Hits	100	Shared Neighborhood Hits	98
SwissProt Accessions	Q14541, Q9UH81, Q9UIS6	Gene names	HNF4G, NR2A2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

NR1D2_MOUSE
θ value	1.33526e-19 (rank : 65)	NC score	0.917082 (rank : 31)
Query Neighborhood Hits	132	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	Q60674, Q60646	Gene names	Nr1d2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (Orphan nuclear receptor RVR).

MCR_HUMAN
θ value	2.27762e-19 (rank : 66)	NC score	0.877598 (rank : 88)
Query Neighborhood Hits	132	Target Neighborhood Hits	149	Shared Neighborhood Hits	94
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

PPARA_MOUSE
θ value	2.27762e-19 (rank : 67)	NC score	0.903384 (rank : 79)
Query Neighborhood Hits	132	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	P23204	Gene names	Ppara, Nr1c1, Ppar
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

PPARA_HUMAN
θ value	2.97466e-19 (rank : 68)	NC score	0.903374 (rank : 80)
Query Neighborhood Hits	132	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q07869, Q16241, Q92486, Q92689, Q9Y3N1	Gene names	PPARA, NR1C1, PPAR
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

HNF4G_MOUSE
θ value	3.88503e-19 (rank : 69)	NC score	0.913791 (rank : 56)
Query Neighborhood Hits	132	Target Neighborhood Hits	101	Shared Neighborhood Hits	98
SwissProt Accessions	Q9WUU6	Gene names	Hnf4g, Nr2a2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

NR1H3_HUMAN
θ value	6.62687e-19 (rank : 70)	NC score	0.912061 (rank : 62)
Query Neighborhood Hits	132	Target Neighborhood Hits	104	Shared Neighborhood Hits	95
SwissProt Accessions	Q13133, Q96H87	Gene names	NR1H3, LXRA
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

NR1I3_MOUSE
θ value	6.62687e-19 (rank : 71)	NC score	0.919252 (rank : 25)
Query Neighborhood Hits	132	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	O35627, O35628	Gene names	Nr1i3, Car
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67).

MCR_MOUSE
θ value	1.13037e-18 (rank : 72)	NC score	0.874544 (rank : 92)
Query Neighborhood Hits	132	Target Neighborhood Hits	162	Shared Neighborhood Hits	94
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

PPARD_MOUSE
θ value	1.13037e-18 (rank : 73)	NC score	0.899985 (rank : 86)
Query Neighborhood Hits	132	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P35396, P37239	Gene names	Ppard, Nr1c2, Pparb
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1).

GCR_MOUSE
θ value	1.47631e-18 (rank : 74)	NC score	0.874824 (rank : 90)
Query Neighborhood Hits	132	Target Neighborhood Hits	117	Shared Neighborhood Hits	94
SwissProt Accessions	P06537, Q61628, Q61629	Gene names	Nr3c1, Grl, Grl1
Domain Architecture
Description	Glucocorticoid receptor (GR).

NR1H4_HUMAN
θ value	1.92812e-18 (rank : 75)	NC score	0.914661 (rank : 47)
Query Neighborhood Hits	132	Target Neighborhood Hits	112	Shared Neighborhood Hits	97
SwissProt Accessions	Q96RI1, Q8NFP5, Q8NFP6, Q92943	Gene names	NR1H4, BAR, FXR, HRR1, RIP14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

NR1H4_MOUSE
θ value	1.92812e-18 (rank : 76)	NC score	0.913988 (rank : 55)
Query Neighborhood Hits	132	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	Q60641, Q60642, Q60643	Gene names	Nr1h4, Bar, Fxr, Rip14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

NR1H3_MOUSE
θ value	3.28887e-18 (rank : 77)	NC score	0.910913 (rank : 65)
Query Neighborhood Hits	132	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Z0Y9, Q9QUH7	Gene names	Nr1h3, Lxra
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

PRGR_HUMAN
θ value	3.28887e-18 (rank : 78)	NC score	0.872297 (rank : 93)
Query Neighborhood Hits	132	Target Neighborhood Hits	163	Shared Neighborhood Hits	99
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

PRGR_MOUSE
θ value	3.28887e-18 (rank : 79)	NC score	0.866947 (rank : 94)
Query Neighborhood Hits	132	Target Neighborhood Hits	286	Shared Neighborhood Hits	101
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

PPARG_HUMAN
θ value	4.29542e-18 (rank : 80)	NC score	0.901332 (rank : 84)
Query Neighborhood Hits	132	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37231, O00684, O00710, O14515, Q15178, Q15179, Q15180, Q15832, Q86U60, Q96J12	Gene names	PPARG, NR1C3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

PPARG_MOUSE
θ value	4.29542e-18 (rank : 81)	NC score	0.901172 (rank : 85)
Query Neighborhood Hits	132	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37238	Gene names	Pparg, Nr1c3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

VDR_MOUSE
θ value	5.60996e-18 (rank : 82)	NC score	0.912211 (rank : 60)
Query Neighborhood Hits	132	Target Neighborhood Hits	103	Shared Neighborhood Hits	96
SwissProt Accessions	P48281	Gene names	Vdr, Nr1i1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

VDR_HUMAN
θ value	7.32683e-18 (rank : 83)	NC score	0.913213 (rank : 57)
Query Neighborhood Hits	132	Target Neighborhood Hits	112	Shared Neighborhood Hits	96
SwissProt Accessions	P11473	Gene names	VDR, NR1I1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

NR2E1_HUMAN
θ value	9.56915e-18 (rank : 84)	NC score	0.914865 (rank : 41)
Query Neighborhood Hits	132	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y466	Gene names	NR2E1, TLX
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (hTll).

ANDR_HUMAN
θ value	1.63225e-17 (rank : 85)	NC score	0.874754 (rank : 91)
Query Neighborhood Hits	132	Target Neighborhood Hits	126	Shared Neighborhood Hits	94
SwissProt Accessions	P10275	Gene names	AR, DHTR, NR3C4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

ANDR_MOUSE
θ value	1.63225e-17 (rank : 86)	NC score	0.874964 (rank : 89)
Query Neighborhood Hits	132	Target Neighborhood Hits	133	Shared Neighborhood Hits	94
SwissProt Accessions	P19091	Gene names	Ar, Nr3c4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

ESR2_HUMAN
θ value	2.13179e-17 (rank : 87)	NC score	0.905459 (rank : 74)
Query Neighborhood Hits	132	Target Neighborhood Hits	110	Shared Neighborhood Hits	97
SwissProt Accessions	Q92731, O60608, O60685, O60702, O60703, O75583, O75584, Q86Z31, Q9UEV6, Q9UHD3, Q9UQK9	Gene names	ESR2, ESTRB, NR3A2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

ESR2_MOUSE
θ value	2.13179e-17 (rank : 88)	NC score	0.905435 (rank : 75)
Query Neighborhood Hits	132	Target Neighborhood Hits	110	Shared Neighborhood Hits	96
SwissProt Accessions	O08537, O35635, O70519	Gene names	Esr2, Estrb, Nr3a2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

PXR_MOUSE
θ value	2.7842e-17 (rank : 89)	NC score	0.905694 (rank : 73)
Query Neighborhood Hits	132	Target Neighborhood Hits	107	Shared Neighborhood Hits	97
SwissProt Accessions	O54915	Gene names	Nr1i2, Pxr
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor).

NR1H2_MOUSE
θ value	3.63628e-17 (rank : 90)	NC score	0.906751 (rank : 71)
Query Neighborhood Hits	132	Target Neighborhood Hits	109	Shared Neighborhood Hits	96
SwissProt Accessions	Q60644	Gene names	Nr1h2, Lxrb, Rip15, Unr, Unr2
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Retinoid X receptor-interacting protein No.15).

NR1H2_HUMAN
θ value	1.058e-16 (rank : 91)	NC score	0.902694 (rank : 82)
Query Neighborhood Hits	132	Target Neighborhood Hits	114	Shared Neighborhood Hits	95
SwissProt Accessions	P55055, Q12970	Gene names	NR1H2, LXRB, NER, UNR
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Nuclear receptor NER).

PXR_HUMAN
θ value	1.80466e-16 (rank : 92)	NC score	0.902605 (rank : 83)
Query Neighborhood Hits	132	Target Neighborhood Hits	107	Shared Neighborhood Hits	97
SwissProt Accessions	O75469, Q96AC7, Q9UJ22, Q9UJ23, Q9UJ24, Q9UJ25, Q9UJ26, Q9UJ27	Gene names	NR1I2, PXR
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor) (Orphan nuclear receptor PAR1) (Steroid and xenobiotic receptor) (SXR).

NR2E3_MOUSE
θ value	2.35696e-16 (rank : 93)	NC score	0.911354 (rank : 64)
Query Neighborhood Hits	132	Target Neighborhood Hits	113	Shared Neighborhood Hits	99
SwissProt Accessions	Q9QXZ7	Gene names	Nr2e3, Pnr, Rnr
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

NR2E3_HUMAN
θ value	4.44505e-15 (rank : 94)	NC score	0.914744 (rank : 42)
Query Neighborhood Hits	132	Target Neighborhood Hits	102	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y5X4, Q9UHM4	Gene names	NR2E3, PNR, RNR
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

DAX1_MOUSE
θ value	0.00035302 (rank : 95)	NC score	0.497348 (rank : 95)
Query Neighborhood Hits	132	Target Neighborhood Hits	70	Shared Neighborhood Hits	60
SwissProt Accessions	Q61066, O09068, O09147	Gene names	Nr0b1, Ahch, Dax1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1).

SHP_MOUSE
θ value	0.000461057 (rank : 96)	NC score	0.488072 (rank : 97)
Query Neighborhood Hits	132	Target Neighborhood Hits	53	Shared Neighborhood Hits	53
SwissProt Accessions	Q62227, Q53Z53	Gene names	Nr0b2, Shp
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

GNAS1_MOUSE
θ value	0.163984 (rank : 97)	NC score	0.011755 (rank : 113)
Query Neighborhood Hits	132	Target Neighborhood Hits	651	Shared Neighborhood Hits	23
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

COBA1_HUMAN
θ value	0.21417 (rank : 98)	NC score	0.012985 (rank : 109)
Query Neighborhood Hits	132	Target Neighborhood Hits	491	Shared Neighborhood Hits	23
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA1_MOUSE
θ value	0.21417 (rank : 99)	NC score	0.009250 (rank : 119)
Query Neighborhood Hits	132	Target Neighborhood Hits	487	Shared Neighborhood Hits	20
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

CEL_HUMAN
θ value	0.813845 (rank : 100)	NC score	0.012229 (rank : 111)
Query Neighborhood Hits	132	Target Neighborhood Hits	896	Shared Neighborhood Hits	26
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

LEG3_MOUSE
θ value	1.06291 (rank : 101)	NC score	0.011933 (rank : 112)
Query Neighborhood Hits	132	Target Neighborhood Hits	113	Shared Neighborhood Hits	10
SwissProt Accessions	P16110	Gene names	Lgals3
Domain Architecture
Description	Galectin-3 (Galactose-specific lectin 3) (Mac-2 antigen) (IgE-binding protein) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Laminin-binding protein) (Lectin L-29) (L-34 galactoside-binding lectin).

SC24D_HUMAN
θ value	1.06291 (rank : 102)	NC score	0.012696 (rank : 110)
Query Neighborhood Hits	132	Target Neighborhood Hits	173	Shared Neighborhood Hits	10
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

SSBP4_HUMAN
θ value	1.06291 (rank : 103)	NC score	0.011238 (rank : 115)
Query Neighborhood Hits	132	Target Neighborhood Hits	753	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

ZIM10_HUMAN
θ value	1.06291 (rank : 104)	NC score	0.015801 (rank : 104)
Query Neighborhood Hits	132	Target Neighborhood Hits	577	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

FUBP1_HUMAN
θ value	1.38821 (rank : 105)	NC score	0.016184 (rank : 102)
Query Neighborhood Hits	132	Target Neighborhood Hits	136	Shared Neighborhood Hits	17
SwissProt Accessions	Q96AE4, Q12828	Gene names	FUBP1
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP) (DNA helicase V) (HDH V).

FUBP1_MOUSE
θ value	1.38821 (rank : 106)	NC score	0.016336 (rank : 101)
Query Neighborhood Hits	132	Target Neighborhood Hits	144	Shared Neighborhood Hits	18
SwissProt Accessions	Q91WJ8, Q8C0Y8	Gene names	Fubp1, D3Ertd330e
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP).

REXO1_HUMAN
θ value	1.81305 (rank : 107)	NC score	0.007465 (rank : 121)
Query Neighborhood Hits	132	Target Neighborhood Hits	242	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

SON_HUMAN
θ value	2.36792 (rank : 108)	NC score	0.007283 (rank : 122)
Query Neighborhood Hits	132	Target Neighborhood Hits	1568	Shared Neighborhood Hits	30
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

BAT3_HUMAN
θ value	3.0926 (rank : 109)	NC score	0.014865 (rank : 107)
Query Neighborhood Hits	132	Target Neighborhood Hits	490	Shared Neighborhood Hits	21
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BAT3_MOUSE
θ value	3.0926 (rank : 110)	NC score	0.014675 (rank : 108)
Query Neighborhood Hits	132	Target Neighborhood Hits	518	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

NIBL_MOUSE
θ value	3.0926 (rank : 111)	NC score	0.008187 (rank : 120)
Query Neighborhood Hits	132	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R1F1	Gene names
Domain Architecture	No domain graphic available
Description	Niban-like protein.

RX_MOUSE
θ value	3.0926 (rank : 112)	NC score	-0.002273 (rank : 129)
Query Neighborhood Hits	132	Target Neighborhood Hits	429	Shared Neighborhood Hits	6
SwissProt Accessions	O35602, O08748	Gene names	Rax, Rx
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

SHP_HUMAN
θ value	3.0926 (rank : 113)	NC score	0.490281 (rank : 96)
Query Neighborhood Hits	132	Target Neighborhood Hits	57	Shared Neighborhood Hits	56
SwissProt Accessions	Q15466, Q5QP36	Gene names	NR0B2, SHP
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

FSTL3_HUMAN
θ value	4.03905 (rank : 114)	NC score	0.015615 (rank : 105)
Query Neighborhood Hits	132	Target Neighborhood Hits	162	Shared Neighborhood Hits	8
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

PA24F_MOUSE
θ value	4.03905 (rank : 115)	NC score	0.003195 (rank : 125)
Query Neighborhood Hits	132	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

TCGAP_HUMAN
θ value	4.03905 (rank : 116)	NC score	0.010569 (rank : 116)
Query Neighborhood Hits	132	Target Neighborhood Hits	872	Shared Neighborhood Hits	25
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

ZN687_HUMAN
θ value	4.03905 (rank : 117)	NC score	-0.002400 (rank : 131)
Query Neighborhood Hits	132	Target Neighborhood Hits	1244	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

MISS_MOUSE
θ value	5.27518 (rank : 118)	NC score	0.022933 (rank : 99)
Query Neighborhood Hits	132	Target Neighborhood Hits	444	Shared Neighborhood Hits	21
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

BCOR_HUMAN
θ value	6.88961 (rank : 119)	NC score	-0.002344 (rank : 130)
Query Neighborhood Hits	132	Target Neighborhood Hits	609	Shared Neighborhood Hits	8
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CN032_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.015281 (rank : 106)
Query Neighborhood Hits	132	Target Neighborhood Hits	267	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CN032_MOUSE
θ value	6.88961 (rank : 121)	NC score	0.016091 (rank : 103)
Query Neighborhood Hits	132	Target Neighborhood Hits	233	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

DAX1_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.456659 (rank : 98)
Query Neighborhood Hits	132	Target Neighborhood Hits	65	Shared Neighborhood Hits	59
SwissProt Accessions	P51843, Q96F69	Gene names	NR0B1, AHC, DAX1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1) (DSS-AHC critical region on the X chromosome protein 1).

HXD11_MOUSE
θ value	6.88961 (rank : 123)	NC score	-0.002782 (rank : 132)
Query Neighborhood Hits	132	Target Neighborhood Hits	376	Shared Neighborhood Hits	7
SwissProt Accessions	P23813	Gene names	Hoxd11, Hox-4.6, Hoxd-11
Domain Architecture
Description	Homeobox protein Hox-D11 (Hox-4.6) (Hox-5.5).

KIF12_MOUSE
θ value	6.88961 (rank : 124)	NC score	-0.000189 (rank : 126)
Query Neighborhood Hits	132	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D2Z8, O35061	Gene names	Kif12
Domain Architecture
Description	Kinesin-like protein KIF12.

PRR13_MOUSE
θ value	6.88961 (rank : 125)	NC score	0.017309 (rank : 100)
Query Neighborhood Hits	132	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

CO4A5_HUMAN
θ value	8.99809 (rank : 126)	NC score	0.011660 (rank : 114)
Query Neighborhood Hits	132	Target Neighborhood Hits	383	Shared Neighborhood Hits	23
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

FGRL1_HUMAN
θ value	8.99809 (rank : 127)	NC score	-0.001894 (rank : 128)
Query Neighborhood Hits	132	Target Neighborhood Hits	335	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

HRBL_MOUSE
θ value	8.99809 (rank : 128)	NC score	0.005004 (rank : 124)
Query Neighborhood Hits	132	Target Neighborhood Hits	269	Shared Neighborhood Hits	13
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

PI5PA_HUMAN
θ value	8.99809 (rank : 129)	NC score	0.009674 (rank : 118)
Query Neighborhood Hits	132	Target Neighborhood Hits	749	Shared Neighborhood Hits	20
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PTN21_MOUSE
θ value	8.99809 (rank : 130)	NC score	-0.001798 (rank : 127)
Query Neighborhood Hits	132	Target Neighborhood Hits	155	Shared Neighborhood Hits	2
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

RC3H1_HUMAN
θ value	8.99809 (rank : 131)	NC score	0.010189 (rank : 117)
Query Neighborhood Hits	132	Target Neighborhood Hits	433	Shared Neighborhood Hits	12
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RNC_HUMAN
θ value	8.99809 (rank : 132)	NC score	0.006830 (rank : 123)
Query Neighborhood Hits	132	Target Neighborhood Hits	176	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

Hits sorted by NC score

STF1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	132	Target Neighborhood Hits	132	Shared Neighborhood Hits	132
SwissProt Accessions	Q13285, O15196	Gene names	NR5A1, AD4BP, FTZF1, SF1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1).

STF1_MOUSE
NC score	0.996868 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	132	Target Neighborhood Hits	137	Shared Neighborhood Hits	107
SwissProt Accessions	P33242	Gene names	Nr5a1, Ftzf1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1) (Embryonal LTR-binding protein) (ELP) (Embryonal long terminal repeat- binding protein) (Steroid hydroxylase positive regulator).

NR5A2_HUMAN
NC score	0.991007 (rank : 3)	θ value	1.91371e-159 (rank : 3)
Query Neighborhood Hits	132	Target Neighborhood Hits	112	Shared Neighborhood Hits	99
SwissProt Accessions	O00482, O95642	Gene names	NR5A2, B1F, CPF, FTF
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Alpha-1-fetoprotein transcription factor) (Hepatocytic transcription factor) (B1-binding factor) (hB1F) (CYP7A promoter-binding factor) (Liver receptor homolog 1) (LRH-1).

NR5A2_MOUSE
NC score	0.990750 (rank : 4)	θ value	5.05951e-144 (rank : 4)
Query Neighborhood Hits	132	Target Neighborhood Hits	107	Shared Neighborhood Hits	98
SwissProt Accessions	P45448	Gene names	Nr5a2, Lrh1
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Liver receptor homolog 1) (LRH-1).

NR6A1_MOUSE
NC score	0.947187 (rank : 5)	θ value	3.86705e-35 (rank : 5)
Query Neighborhood Hits	132	Target Neighborhood Hits	110	Shared Neighborhood Hits	98
SwissProt Accessions	Q64249	Gene names	Nr6a1, Gcnf
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

NR6A1_HUMAN
NC score	0.944446 (rank : 6)	θ value	1.99067e-23 (rank : 25)
Query Neighborhood Hits	132	Target Neighborhood Hits	108	Shared Neighborhood Hits	98
SwissProt Accessions	Q15406, O00551, O00603, Q8NHQ0, Q92898, Q99802	Gene names	NR6A1, GCNF
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

ERR1_HUMAN
NC score	0.929223 (rank : 7)	θ value	5.59698e-26 (rank : 10)
Query Neighborhood Hits	132	Target Neighborhood Hits	157	Shared Neighborhood Hits	99
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

ERR2_HUMAN
NC score	0.925547 (rank : 8)	θ value	8.63488e-27 (rank : 7)
Query Neighborhood Hits	132	Target Neighborhood Hits	108	Shared Neighborhood Hits	98
SwissProt Accessions	O95718, Q9HCB4	Gene names	ESRRB, ERRB2, NR3B2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2) (ERR beta-2).

ERR2_MOUSE
NC score	0.925224 (rank : 9)	θ value	6.61148e-27 (rank : 6)
Query Neighborhood Hits	132	Target Neighborhood Hits	109	Shared Neighborhood Hits	98
SwissProt Accessions	Q61539, O09067, O09146	Gene names	Esrrb, Err-2, Err2, Nr3b2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2).

NR4A3_HUMAN
NC score	0.925027 (rank : 10)	θ value	1.37858e-24 (rank : 16)
Query Neighborhood Hits	132	Target Neighborhood Hits	131	Shared Neighborhood Hits	96
SwissProt Accessions	Q92570, Q12935, Q14979, Q16420, Q4VXA9, Q9UEK2, Q9UEK3	Gene names	NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1) (Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphan receptor).

NR4A3_MOUSE
NC score	0.924431 (rank : 11)	θ value	1.37858e-24 (rank : 17)
Query Neighborhood Hits	132	Target Neighborhood Hits	127	Shared Neighborhood Hits	96
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

ERR3_HUMAN
NC score	0.924264 (rank : 12)	θ value	1.47289e-26 (rank : 8)
Query Neighborhood Hits	132	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P62508, O75454, O96021, Q68DA0, Q6P274, Q6PK28, Q6TS38, Q9R1F3, Q9UNJ4	Gene names	ESRRG, ERR3, ERRG2, KIAA0832, NR3B3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (ERR gamma-2).

ERR3_MOUSE
NC score	0.924264 (rank : 13)	θ value	1.47289e-26 (rank : 9)
Query Neighborhood Hits	132	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P62509, O75454, O96021, Q8CHC9, Q9R1F3	Gene names	Esrrg, Err3, Kiaa0832, Nr3b3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3).

NR4A1_MOUSE
NC score	0.923249 (rank : 14)	θ value	4.01107e-24 (rank : 20)
Query Neighborhood Hits	132	Target Neighborhood Hits	128	Shared Neighborhood Hits	95
SwissProt Accessions	P12813	Gene names	Nr4a1, Gfrp, Hmr, N10, Nur77
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Nuclear hormone receptor NUR/77) (N10 nuclear protein).

NR4A1_HUMAN
NC score	0.923178 (rank : 15)	θ value	1.05554e-24 (rank : 13)
Query Neighborhood Hits	132	Target Neighborhood Hits	133	Shared Neighborhood Hits	96
SwissProt Accessions	P22736	Gene names	NR4A1, GFRP1, HMR, NAK1
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Early response protein NAK1) (TR3 orphan receptor) (ST-59).

RXRG_MOUSE
NC score	0.922732 (rank : 16)	θ value	6.84181e-24 (rank : 22)
Query Neighborhood Hits	132	Target Neighborhood Hits	113	Shared Neighborhood Hits	98
SwissProt Accessions	P28705	Gene names	Rxrg, Nr2b3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

RXRA_MOUSE
NC score	0.922643 (rank : 17)	θ value	8.08199e-25 (rank : 12)
Query Neighborhood Hits	132	Target Neighborhood Hits	129	Shared Neighborhood Hits	101
SwissProt Accessions	P28700	Gene names	Rxra, Nr2b1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

RXRG_HUMAN
NC score	0.922257 (rank : 18)	θ value	6.84181e-24 (rank : 21)
Query Neighborhood Hits	132	Target Neighborhood Hits	114	Shared Neighborhood Hits	98
SwissProt Accessions	P48443	Gene names	RXRG, NR2B3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

NR1D1_HUMAN
NC score	0.922138 (rank : 19)	θ value	1.5773e-20 (rank : 54)
Query Neighborhood Hits	132	Target Neighborhood Hits	140	Shared Neighborhood Hits	94
SwissProt Accessions	P20393, Q15304	Gene names	NR1D1, EAR1, HREV, THRAL
Domain Architecture
Description	Orphan nuclear receptor NR1D1 (V-erbA-related protein EAR-1) (Rev- erbA-alpha).

NR4A2_HUMAN
NC score	0.922009 (rank : 20)	θ value	1.05554e-24 (rank : 14)
Query Neighborhood Hits	132	Target Neighborhood Hits	120	Shared Neighborhood Hits	95
SwissProt Accessions	P43354, Q16311	Gene names	NR4A2, NOT, NURR1, TINUR
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (Immediate-early response protein NOT) (Transcriptionally-inducible nuclear receptor).

NR4A2_MOUSE
NC score	0.921981 (rank : 21)	θ value	1.05554e-24 (rank : 15)
Query Neighborhood Hits	132	Target Neighborhood Hits	121	Shared Neighborhood Hits	95
SwissProt Accessions	Q06219, O08690	Gene names	Nr4a2, Nurr1
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (NUR- related factor 1).

TR2_HUMAN
NC score	0.920663 (rank : 22)	θ value	3.17815e-21 (rank : 53)
Query Neighborhood Hits	132	Target Neighborhood Hits	110	Shared Neighborhood Hits	97
SwissProt Accessions	P13056	Gene names	NR2C1, TR2
Domain Architecture
Description	Orphan nuclear receptor TR2 (Testicular receptor 2).

NR1I3_HUMAN
NC score	0.920540 (rank : 23)	θ value	4.58923e-20 (rank : 57)
Query Neighborhood Hits	132	Target Neighborhood Hits	107	Shared Neighborhood Hits	99
SwissProt Accessions	Q14994	Gene names	NR1I3, CAR
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Constitutive activator of retinoid response) (Constitutive active response) (Orphan nuclear receptor MB67).

RXRA_HUMAN
NC score	0.919612 (rank : 24)	θ value	8.08199e-25 (rank : 11)
Query Neighborhood Hits	132	Target Neighborhood Hits	223	Shared Neighborhood Hits	99
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

NR1I3_MOUSE
NC score	0.919252 (rank : 25)	θ value	6.62687e-19 (rank : 71)
Query Neighborhood Hits	132	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	O35627, O35628	Gene names	Nr1i3, Car
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67).

RXRB_MOUSE
NC score	0.918745 (rank : 26)	θ value	2.35151e-24 (rank : 19)
Query Neighborhood Hits	132	Target Neighborhood Hits	230	Shared Neighborhood Hits	107
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

TR2_MOUSE
NC score	0.918051 (rank : 27)	θ value	1.86321e-21 (rank : 49)
Query Neighborhood Hits	132	Target Neighborhood Hits	100	Shared Neighborhood Hits	98
SwissProt Accessions	Q505F1, P97763, Q3UIJ7, Q4U1Z4, Q60927, Q62152, Q8VIJ3	Gene names	Nr2c1, Tr2, Tr2-11
Domain Architecture	No domain graphic available
Description	Orphan nuclear receptor TR2 (Testicular receptor 2) (mTR2).

RORB_MOUSE
NC score	0.917394 (rank : 28)	θ value	8.93572e-24 (rank : 24)
Query Neighborhood Hits	132	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	Q8R1B8	Gene names	Rorb, Nr1f2
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

NR2E1_MOUSE
NC score	0.917132 (rank : 29)	θ value	1.02238e-19 (rank : 59)
Query Neighborhood Hits	132	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	Q64104	Gene names	Nr2e1, Tll, Tlx
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (mTll).

RORB_HUMAN
NC score	0.917099 (rank : 30)	θ value	8.93572e-24 (rank : 23)
Query Neighborhood Hits	132	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	Q92753, Q8WX73	Gene names	RORB, NR1F2, RZRB
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

NR1D2_MOUSE
NC score	0.917082 (rank : 31)	θ value	1.33526e-19 (rank : 65)
Query Neighborhood Hits	132	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	Q60674, Q60646	Gene names	Nr1d2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (Orphan nuclear receptor RVR).

EAR2_HUMAN
NC score	0.916832 (rank : 32)	θ value	3.17815e-21 (rank : 52)
Query Neighborhood Hits	132	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P10588, Q9BUE8	Gene names	NR2F6, EAR2, ERBAL2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

EAR2_MOUSE
NC score	0.916467 (rank : 33)	θ value	1.09232e-21 (rank : 44)
Query Neighborhood Hits	132	Target Neighborhood Hits	104	Shared Neighborhood Hits	98
SwissProt Accessions	P43136, Q61504	Gene names	Nr2f6, Ear-2, Ear2, Erbal2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

RXRB_HUMAN
NC score	0.916273 (rank : 34)	θ value	2.35151e-24 (rank : 18)
Query Neighborhood Hits	132	Target Neighborhood Hits	280	Shared Neighborhood Hits	107
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

RORA_HUMAN
NC score	0.915698 (rank : 35)	θ value	5.79196e-23 (rank : 26)
Query Neighborhood Hits	132	Target Neighborhood Hits	105	Shared Neighborhood Hits	95
SwissProt Accessions	P35398, P35397, P35399, P45445, Q96H83	Gene names	RORA, NR1F1, RZRA
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

RORA_MOUSE
NC score	0.915634 (rank : 36)	θ value	5.79196e-23 (rank : 27)
Query Neighborhood Hits	132	Target Neighborhood Hits	105	Shared Neighborhood Hits	95
SwissProt Accessions	P51448, P70283, P97741, P97773, Q923G1	Gene names	Rora, Nr1f1, Rzra
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

RARG2_HUMAN
NC score	0.915213 (rank : 37)	θ value	4.9032e-22 (rank : 38)
Query Neighborhood Hits	132	Target Neighborhood Hits	109	Shared Neighborhood Hits	95
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

RORG_MOUSE
NC score	0.915206 (rank : 38)	θ value	7.56453e-23 (rank : 29)
Query Neighborhood Hits	132	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	P51450, Q61027, Q91YT5, Q9QXD9, Q9R177	Gene names	Rorc, Nr1f3, Rorg, Thor
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma) (Thymus orphan receptor) (TOR).

RARG1_HUMAN
NC score	0.915070 (rank : 39)	θ value	4.9032e-22 (rank : 36)
Query Neighborhood Hits	132	Target Neighborhood Hits	107	Shared Neighborhood Hits	95
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARG2_MOUSE
NC score	0.915025 (rank : 40)	θ value	4.9032e-22 (rank : 39)
Query Neighborhood Hits	132	Target Neighborhood Hits	114	Shared Neighborhood Hits	95
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

NR2E1_HUMAN
NC score	0.914865 (rank : 41)	θ value	9.56915e-18 (rank : 84)
Query Neighborhood Hits	132	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y466	Gene names	NR2E1, TLX
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (hTll).

NR2E3_HUMAN
NC score	0.914744 (rank : 42)	θ value	4.44505e-15 (rank : 94)
Query Neighborhood Hits	132	Target Neighborhood Hits	102	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y5X4, Q9UHM4	Gene names	NR2E3, PNR, RNR
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

RARG1_MOUSE
NC score	0.914735 (rank : 43)	θ value	4.9032e-22 (rank : 37)
Query Neighborhood Hits	132	Target Neighborhood Hits	113	Shared Neighborhood Hits	95
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

HNF4A_MOUSE
NC score	0.914719 (rank : 44)	θ value	1.33526e-19 (rank : 63)
Query Neighborhood Hits	132	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	P49698	Gene names	Hnf4a, Hnf-4, Hnf4, Nr2a1, Tcf14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

HNF4G_HUMAN
NC score	0.914698 (rank : 45)	θ value	1.33526e-19 (rank : 64)
Query Neighborhood Hits	132	Target Neighborhood Hits	100	Shared Neighborhood Hits	98
SwissProt Accessions	Q14541, Q9UH81, Q9UIS6	Gene names	HNF4G, NR2A2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

NR1D2_HUMAN
NC score	0.914690 (rank : 46)	θ value	1.02238e-19 (rank : 58)
Query Neighborhood Hits	132	Target Neighborhood Hits	115	Shared Neighborhood Hits	94
SwissProt Accessions	Q14995, O00402, Q86XD4	Gene names	NR1D2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (EAR-1R) (Orphan nuclear hormone receptor BD73).

NR1H4_HUMAN
NC score	0.914661 (rank : 47)	θ value	1.92812e-18 (rank : 75)
Query Neighborhood Hits	132	Target Neighborhood Hits	112	Shared Neighborhood Hits	97
SwissProt Accessions	Q96RI1, Q8NFP5, Q8NFP6, Q92943	Gene names	NR1H4, BAR, FXR, HRR1, RIP14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

RARA_MOUSE
NC score	0.914376 (rank : 48)	θ value	2.43343e-21 (rank : 51)
Query Neighborhood Hits	132	Target Neighborhood Hits	113	Shared Neighborhood Hits	96
SwissProt Accessions	P11416, P22603	Gene names	Rara, Nr1b1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

HNF4A_HUMAN
NC score	0.914273 (rank : 49)	θ value	1.33526e-19 (rank : 62)
Query Neighborhood Hits	132	Target Neighborhood Hits	105	Shared Neighborhood Hits	98
SwissProt Accessions	P41235, O00659, O00723, Q14540, Q92653, Q92654, Q92655, Q99864, Q9NQH0	Gene names	HNF4A, HNF4, NR2A1, TCF14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

RARA_HUMAN
NC score	0.914236 (rank : 50)	θ value	2.43343e-21 (rank : 50)
Query Neighborhood Hits	132	Target Neighborhood Hits	118	Shared Neighborhood Hits	96
SwissProt Accessions	P10276, P78456, Q13440, Q13441, Q9NQS0	Gene names	RARA, NR1B1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARB_MOUSE
NC score	0.914044 (rank : 51)	θ value	1.86321e-21 (rank : 48)
Query Neighborhood Hits	132	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	P22605, P11417, P22604	Gene names	Rarb, Nr1b2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta).

COT2_HUMAN
NC score	0.914042 (rank : 52)	θ value	1.09232e-21 (rank : 42)
Query Neighborhood Hits	132	Target Neighborhood Hits	135	Shared Neighborhood Hits	99
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT2_MOUSE
NC score	0.914042 (rank : 53)	θ value	1.09232e-21 (rank : 43)
Query Neighborhood Hits	132	Target Neighborhood Hits	135	Shared Neighborhood Hits	99
SwissProt Accessions	P43135	Gene names	Nr2f2, Aporp1, Arp-1, Arp1, Tfcoup2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

RARB_HUMAN
NC score	0.914030 (rank : 54)	θ value	1.86321e-21 (rank : 47)
Query Neighborhood Hits	132	Target Neighborhood Hits	118	Shared Neighborhood Hits	94
SwissProt Accessions	P10826, P12891, Q00989, Q15298, Q9UN48	Gene names	RARB, HAP, NR1B2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta) (RAR-epsilon) (HBV-activated protein).

NR1H4_MOUSE
NC score	0.913988 (rank : 55)	θ value	1.92812e-18 (rank : 76)
Query Neighborhood Hits	132	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	Q60641, Q60642, Q60643	Gene names	Nr1h4, Bar, Fxr, Rip14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

HNF4G_MOUSE
NC score	0.913791 (rank : 56)	θ value	3.88503e-19 (rank : 69)
Query Neighborhood Hits	132	Target Neighborhood Hits	101	Shared Neighborhood Hits	98
SwissProt Accessions	Q9WUU6	Gene names	Hnf4g, Nr2a2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

VDR_HUMAN
NC score	0.913213 (rank : 57)	θ value	7.32683e-18 (rank : 83)
Query Neighborhood Hits	132	Target Neighborhood Hits	112	Shared Neighborhood Hits	96
SwissProt Accessions	P11473	Gene names	VDR, NR1I1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

COT1_MOUSE
NC score	0.912876 (rank : 58)	θ value	1.42661e-21 (rank : 46)
Query Neighborhood Hits	132	Target Neighborhood Hits	160	Shared Neighborhood Hits	102
SwissProt Accessions	Q60632, Q61438	Gene names	Nr2f1, Erbal3, Tfcoup1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I).

COT1_HUMAN
NC score	0.912644 (rank : 59)	θ value	1.42661e-21 (rank : 45)
Query Neighborhood Hits	132	Target Neighborhood Hits	159	Shared Neighborhood Hits	103
SwissProt Accessions	P10589	Gene names	NR2F1, EAR3, ERBAL3, TFCOUP1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I) (V-ERBA-related protein EAR-3).

VDR_MOUSE
NC score	0.912211 (rank : 60)	θ value	5.60996e-18 (rank : 82)
Query Neighborhood Hits	132	Target Neighborhood Hits	103	Shared Neighborhood Hits	96
SwissProt Accessions	P48281	Gene names	Vdr, Nr1i1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

RORG_HUMAN
NC score	0.912090 (rank : 61)	θ value	1.6852e-22 (rank : 33)
Query Neighborhood Hits	132	Target Neighborhood Hits	119	Shared Neighborhood Hits	95
SwissProt Accessions	P51449, Q8N5V7, Q8NCY8	Gene names	RORC, NR1F3, RORG, RZRG
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma).

NR1H3_HUMAN
NC score	0.912061 (rank : 62)	θ value	6.62687e-19 (rank : 70)
Query Neighborhood Hits	132	Target Neighborhood Hits	104	Shared Neighborhood Hits	95
SwissProt Accessions	Q13133, Q96H87	Gene names	NR1H3, LXRA
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

ESR1_MOUSE
NC score	0.911547 (rank : 63)	θ value	4.58923e-20 (rank : 56)
Query Neighborhood Hits	132	Target Neighborhood Hits	104	Shared Neighborhood Hits	95
SwissProt Accessions	P19785, Q9JJT5, Q9QY51, Q9QY52	Gene names	Esr1, Esr, Estr, Estra, Nr3a1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

NR2E3_MOUSE
NC score	0.911354 (rank : 64)	θ value	2.35696e-16 (rank : 93)
Query Neighborhood Hits	132	Target Neighborhood Hits	113	Shared Neighborhood Hits	99
SwissProt Accessions	Q9QXZ7	Gene names	Nr2e3, Pnr, Rnr
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

NR1H3_MOUSE
NC score	0.910913 (rank : 65)	θ value	3.28887e-18 (rank : 77)
Query Neighborhood Hits	132	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Z0Y9, Q9QUH7	Gene names	Nr1h3, Lxra
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

THA_MOUSE
NC score	0.910741 (rank : 66)	θ value	9.87957e-23 (rank : 31)
Query Neighborhood Hits	132	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	P63058, P10685, P15827, P16416, P37241, Q63107, Q63195, Q63196, Q99146	Gene names	Thra, C-erba-alpha, Nr1a1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1).

THA_HUMAN
NC score	0.910733 (rank : 67)	θ value	9.87957e-23 (rank : 30)
Query Neighborhood Hits	132	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	P10827, P21205, Q8N6A1, Q96H73	Gene names	THRA, ERBA1, NR1A1, THRA1
Domain Architecture
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1) (EAR-7) (EAR7).

ESR1_HUMAN
NC score	0.910152 (rank : 68)	θ value	4.58923e-20 (rank : 55)
Query Neighborhood Hits	132	Target Neighborhood Hits	105	Shared Neighborhood Hits	96
SwissProt Accessions	P03372, Q13511, Q14276, Q9NU51, Q9UDZ7, Q9UIS7	Gene names	ESR1, ESR, NR3A1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

TR4_HUMAN
NC score	0.909760 (rank : 69)	θ value	1.29031e-22 (rank : 32)
Query Neighborhood Hits	132	Target Neighborhood Hits	117	Shared Neighborhood Hits	98
SwissProt Accessions	P49116, P55092	Gene names	NR2C2, TAK1, TR4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

TR4_MOUSE
NC score	0.909614 (rank : 70)	θ value	5.79196e-23 (rank : 28)
Query Neighborhood Hits	132	Target Neighborhood Hits	115	Shared Neighborhood Hits	98
SwissProt Accessions	P49117, P55093	Gene names	Nr2c2, Mtr2r1, Tak1, Tr4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

NR1H2_MOUSE
NC score	0.906751 (rank : 71)	θ value	3.63628e-17 (rank : 90)
Query Neighborhood Hits	132	Target Neighborhood Hits	109	Shared Neighborhood Hits	96
SwissProt Accessions	Q60644	Gene names	Nr1h2, Lxrb, Rip15, Unr, Unr2
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Retinoid X receptor-interacting protein No.15).

THB2_HUMAN
NC score	0.905808 (rank : 72)	θ value	1.6852e-22 (rank : 35)
Query Neighborhood Hits	132	Target Neighborhood Hits	104	Shared Neighborhood Hits	98
SwissProt Accessions	P37243	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor beta-2.

PXR_MOUSE
NC score	0.905694 (rank : 73)	θ value	2.7842e-17 (rank : 89)
Query Neighborhood Hits	132	Target Neighborhood Hits	107	Shared Neighborhood Hits	97
SwissProt Accessions	O54915	Gene names	Nr1i2, Pxr
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor).

ESR2_HUMAN
NC score	0.905459 (rank : 74)	θ value	2.13179e-17 (rank : 87)
Query Neighborhood Hits	132	Target Neighborhood Hits	110	Shared Neighborhood Hits	97
SwissProt Accessions	Q92731, O60608, O60685, O60702, O60703, O75583, O75584, Q86Z31, Q9UEV6, Q9UHD3, Q9UQK9	Gene names	ESR2, ESTRB, NR3A2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

ESR2_MOUSE
NC score	0.905435 (rank : 75)	θ value	2.13179e-17 (rank : 88)
Query Neighborhood Hits	132	Target Neighborhood Hits	110	Shared Neighborhood Hits	96
SwissProt Accessions	O08537, O35635, O70519	Gene names	Esr2, Estrb, Nr3a2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

THB1_HUMAN
NC score	0.905093 (rank : 76)	θ value	1.6852e-22 (rank : 34)
Query Neighborhood Hits	132	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P10828, Q13986	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture
Description	Thyroid hormone receptor beta-1.

THB1_MOUSE
NC score	0.903992 (rank : 77)	θ value	8.36355e-22 (rank : 40)
Query Neighborhood Hits	132	Target Neighborhood Hits	105	Shared Neighborhood Hits	98
SwissProt Accessions	P37242	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-1.

THB2_MOUSE
NC score	0.903928 (rank : 78)	θ value	8.36355e-22 (rank : 41)
Query Neighborhood Hits	132	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P37244	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-2.

PPARA_MOUSE
NC score	0.903384 (rank : 79)	θ value	2.27762e-19 (rank : 67)
Query Neighborhood Hits	132	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	P23204	Gene names	Ppara, Nr1c1, Ppar
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

PPARA_HUMAN
NC score	0.903374 (rank : 80)	θ value	2.97466e-19 (rank : 68)
Query Neighborhood Hits	132	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q07869, Q16241, Q92486, Q92689, Q9Y3N1	Gene names	PPARA, NR1C1, PPAR
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

PPARD_HUMAN
NC score	0.903037 (rank : 81)	θ value	1.02238e-19 (rank : 60)
Query Neighborhood Hits	132	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q03181, Q7Z5K0, Q9BUD4	Gene names	PPARD, NR1C2, PPARB
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1) (NUCI).

NR1H2_HUMAN
NC score	0.902694 (rank : 82)	θ value	1.058e-16 (rank : 91)
Query Neighborhood Hits	132	Target Neighborhood Hits	114	Shared Neighborhood Hits	95
SwissProt Accessions	P55055, Q12970	Gene names	NR1H2, LXRB, NER, UNR
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Nuclear receptor NER).

PXR_HUMAN
NC score	0.902605 (rank : 83)	θ value	1.80466e-16 (rank : 92)
Query Neighborhood Hits	132	Target Neighborhood Hits	107	Shared Neighborhood Hits	97
SwissProt Accessions	O75469, Q96AC7, Q9UJ22, Q9UJ23, Q9UJ24, Q9UJ25, Q9UJ26, Q9UJ27	Gene names	NR1I2, PXR
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor) (Orphan nuclear receptor PAR1) (Steroid and xenobiotic receptor) (SXR).

PPARG_HUMAN
NC score	0.901332 (rank : 84)	θ value	4.29542e-18 (rank : 80)
Query Neighborhood Hits	132	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37231, O00684, O00710, O14515, Q15178, Q15179, Q15180, Q15832, Q86U60, Q96J12	Gene names	PPARG, NR1C3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

PPARG_MOUSE
NC score	0.901172 (rank : 85)	θ value	4.29542e-18 (rank : 81)
Query Neighborhood Hits	132	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37238	Gene names	Pparg, Nr1c3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

PPARD_MOUSE
NC score	0.899985 (rank : 86)	θ value	1.13037e-18 (rank : 73)
Query Neighborhood Hits	132	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P35396, P37239	Gene names	Ppard, Nr1c2, Pparb
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1).

GCR_HUMAN
NC score	0.880441 (rank : 87)	θ value	1.33526e-19 (rank : 61)
Query Neighborhood Hits	132	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P04150, P04151, Q53EP5, Q6N0A4	Gene names	NR3C1, GRL
Domain Architecture
Description	Glucocorticoid receptor (GR).

MCR_HUMAN
NC score	0.877598 (rank : 88)	θ value	2.27762e-19 (rank : 66)
Query Neighborhood Hits	132	Target Neighborhood Hits	149	Shared Neighborhood Hits	94
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

ANDR_MOUSE
NC score	0.874964 (rank : 89)	θ value	1.63225e-17 (rank : 86)
Query Neighborhood Hits	132	Target Neighborhood Hits	133	Shared Neighborhood Hits	94
SwissProt Accessions	P19091	Gene names	Ar, Nr3c4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

GCR_MOUSE
NC score	0.874824 (rank : 90)	θ value	1.47631e-18 (rank : 74)
Query Neighborhood Hits	132	Target Neighborhood Hits	117	Shared Neighborhood Hits	94
SwissProt Accessions	P06537, Q61628, Q61629	Gene names	Nr3c1, Grl, Grl1
Domain Architecture
Description	Glucocorticoid receptor (GR).

ANDR_HUMAN
NC score	0.874754 (rank : 91)	θ value	1.63225e-17 (rank : 85)
Query Neighborhood Hits	132	Target Neighborhood Hits	126	Shared Neighborhood Hits	94
SwissProt Accessions	P10275	Gene names	AR, DHTR, NR3C4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

MCR_MOUSE
NC score	0.874544 (rank : 92)	θ value	1.13037e-18 (rank : 72)
Query Neighborhood Hits	132	Target Neighborhood Hits	162	Shared Neighborhood Hits	94
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

PRGR_HUMAN
NC score	0.872297 (rank : 93)	θ value	3.28887e-18 (rank : 78)
Query Neighborhood Hits	132	Target Neighborhood Hits	163	Shared Neighborhood Hits	99
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

PRGR_MOUSE
NC score	0.866947 (rank : 94)	θ value	3.28887e-18 (rank : 79)
Query Neighborhood Hits	132	Target Neighborhood Hits	286	Shared Neighborhood Hits	101
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

DAX1_MOUSE
NC score	0.497348 (rank : 95)	θ value	0.00035302 (rank : 95)
Query Neighborhood Hits	132	Target Neighborhood Hits	70	Shared Neighborhood Hits	60
SwissProt Accessions	Q61066, O09068, O09147	Gene names	Nr0b1, Ahch, Dax1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1).

SHP_HUMAN
NC score	0.490281 (rank : 96)	θ value	3.0926 (rank : 113)
Query Neighborhood Hits	132	Target Neighborhood Hits	57	Shared Neighborhood Hits	56
SwissProt Accessions	Q15466, Q5QP36	Gene names	NR0B2, SHP
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

SHP_MOUSE
NC score	0.488072 (rank : 97)	θ value	0.000461057 (rank : 96)
Query Neighborhood Hits	132	Target Neighborhood Hits	53	Shared Neighborhood Hits	53
SwissProt Accessions	Q62227, Q53Z53	Gene names	Nr0b2, Shp
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

DAX1_HUMAN
NC score	0.456659 (rank : 98)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	132	Target Neighborhood Hits	65	Shared Neighborhood Hits	59
SwissProt Accessions	P51843, Q96F69	Gene names	NR0B1, AHC, DAX1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1) (DSS-AHC critical region on the X chromosome protein 1).

MISS_MOUSE
NC score	0.022933 (rank : 99)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	132	Target Neighborhood Hits	444	Shared Neighborhood Hits	21
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

PRR13_MOUSE
NC score	0.017309 (rank : 100)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	132	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

FUBP1_MOUSE
NC score	0.016336 (rank : 101)	θ value	1.38821 (rank : 106)
Query Neighborhood Hits	132	Target Neighborhood Hits	144	Shared Neighborhood Hits	18
SwissProt Accessions	Q91WJ8, Q8C0Y8	Gene names	Fubp1, D3Ertd330e
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP).

FUBP1_HUMAN
NC score	0.016184 (rank : 102)	θ value	1.38821 (rank : 105)
Query Neighborhood Hits	132	Target Neighborhood Hits	136	Shared Neighborhood Hits	17
SwissProt Accessions	Q96AE4, Q12828	Gene names	FUBP1
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP) (DNA helicase V) (HDH V).

CN032_MOUSE
NC score	0.016091 (rank : 103)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	132	Target Neighborhood Hits	233	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

ZIM10_HUMAN
NC score	0.015801 (rank : 104)	θ value	1.06291 (rank : 104)
Query Neighborhood Hits	132	Target Neighborhood Hits	577	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

FSTL3_HUMAN
NC score	0.015615 (rank : 105)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	132	Target Neighborhood Hits	162	Shared Neighborhood Hits	8
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

CN032_HUMAN
NC score	0.015281 (rank : 106)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	132	Target Neighborhood Hits	267	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

BAT3_HUMAN
NC score	0.014865 (rank : 107)	θ value	3.0926 (rank : 109)
Query Neighborhood Hits	132	Target Neighborhood Hits	490	Shared Neighborhood Hits	21
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BAT3_MOUSE
NC score	0.014675 (rank : 108)	θ value	3.0926 (rank : 110)
Query Neighborhood Hits	132	Target Neighborhood Hits	518	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

COBA1_HUMAN
NC score	0.012985 (rank : 109)	θ value	0.21417 (rank : 98)
Query Neighborhood Hits	132	Target Neighborhood Hits	491	Shared Neighborhood Hits	23
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

SC24D_HUMAN
NC score	0.012696 (rank : 110)	θ value	1.06291 (rank : 102)
Query Neighborhood Hits	132	Target Neighborhood Hits	173	Shared Neighborhood Hits	10
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

CEL_HUMAN
NC score	0.012229 (rank : 111)	θ value	0.813845 (rank : 100)
Query Neighborhood Hits	132	Target Neighborhood Hits	896	Shared Neighborhood Hits	26
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

LEG3_MOUSE
NC score	0.011933 (rank : 112)	θ value	1.06291 (rank : 101)
Query Neighborhood Hits	132	Target Neighborhood Hits	113	Shared Neighborhood Hits	10
SwissProt Accessions	P16110	Gene names	Lgals3
Domain Architecture
Description	Galectin-3 (Galactose-specific lectin 3) (Mac-2 antigen) (IgE-binding protein) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Laminin-binding protein) (Lectin L-29) (L-34 galactoside-binding lectin).

GNAS1_MOUSE
NC score	0.011755 (rank : 113)	θ value	0.163984 (rank : 97)
Query Neighborhood Hits	132	Target Neighborhood Hits	651	Shared Neighborhood Hits	23
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

CO4A5_HUMAN
NC score	0.011660 (rank : 114)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	132	Target Neighborhood Hits	383	Shared Neighborhood Hits	23
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

SSBP4_HUMAN
NC score	0.011238 (rank : 115)	θ value	1.06291 (rank : 103)
Query Neighborhood Hits	132	Target Neighborhood Hits	753	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

TCGAP_HUMAN
NC score	0.010569 (rank : 116)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	132	Target Neighborhood Hits	872	Shared Neighborhood Hits	25
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RC3H1_HUMAN
NC score	0.010189 (rank : 117)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	132	Target Neighborhood Hits	433	Shared Neighborhood Hits	12
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

PI5PA_HUMAN
NC score	0.009674 (rank : 118)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	132	Target Neighborhood Hits	749	Shared Neighborhood Hits	20
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

COBA1_MOUSE
NC score	0.009250 (rank : 119)	θ value	0.21417 (rank : 99)
Query Neighborhood Hits	132	Target Neighborhood Hits	487	Shared Neighborhood Hits	20
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

NIBL_MOUSE
NC score	0.008187 (rank : 120)	θ value	3.0926 (rank : 111)
Query Neighborhood Hits	132	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R1F1	Gene names
Domain Architecture	No domain graphic available
Description	Niban-like protein.

REXO1_HUMAN
NC score	0.007465 (rank : 121)	θ value	1.81305 (rank : 107)
Query Neighborhood Hits	132	Target Neighborhood Hits	242	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

SON_HUMAN
NC score	0.007283 (rank : 122)	θ value	2.36792 (rank : 108)
Query Neighborhood Hits	132	Target Neighborhood Hits	1568	Shared Neighborhood Hits	30
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

RNC_HUMAN
NC score	0.006830 (rank : 123)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	132	Target Neighborhood Hits	176	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

HRBL_MOUSE
NC score	0.005004 (rank : 124)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	132	Target Neighborhood Hits	269	Shared Neighborhood Hits	13
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

PA24F_MOUSE
NC score	0.003195 (rank : 125)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	132	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

KIF12_MOUSE
NC score	-0.000189 (rank : 126)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	132	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D2Z8, O35061	Gene names	Kif12
Domain Architecture
Description	Kinesin-like protein KIF12.

PTN21_MOUSE
NC score	-0.001798 (rank : 127)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	132	Target Neighborhood Hits	155	Shared Neighborhood Hits	2
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

FGRL1_HUMAN
NC score	-0.001894 (rank : 128)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	132	Target Neighborhood Hits	335	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

RX_MOUSE
NC score	-0.002273 (rank : 129)	θ value	3.0926 (rank : 112)
Query Neighborhood Hits	132	Target Neighborhood Hits	429	Shared Neighborhood Hits	6
SwissProt Accessions	O35602, O08748	Gene names	Rax, Rx
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

BCOR_HUMAN
NC score	-0.002344 (rank : 130)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	132	Target Neighborhood Hits	609	Shared Neighborhood Hits	8
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ZN687_HUMAN
NC score	-0.002400 (rank : 131)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	132	Target Neighborhood Hits	1244	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

HXD11_MOUSE
NC score	-0.002782 (rank : 132)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	132	Target Neighborhood Hits	376	Shared Neighborhood Hits	7
SwissProt Accessions	P23813	Gene names	Hoxd11, Hox-4.6, Hoxd-11
Domain Architecture
Description	Homeobox protein Hox-D11 (Hox-4.6) (Hox-5.5).