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Network neighborhood for query Sequence : NR4A2_HUMAN

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NR4A2_HUMAN
SwissProt Accessions	P43354, Q16311	Gene names	NR4A2, NOT, NURR1, TINUR
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (Immediate-early response protein NOT) (Transcriptionally-inducible nuclear receptor).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NR4A2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	120	Target Neighborhood Hits	120	Shared Neighborhood Hits	120
SwissProt Accessions	P43354, Q16311	Gene names	NR4A2, NOT, NURR1, TINUR
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (Immediate-early response protein NOT) (Transcriptionally-inducible nuclear receptor).

NR4A2_MOUSE
θ value	0 (rank : 2)	NC score	0.999888 (rank : 2)
Query Neighborhood Hits	120	Target Neighborhood Hits	121	Shared Neighborhood Hits	118
SwissProt Accessions	Q06219, O08690	Gene names	Nr4a2, Nurr1
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (NUR- related factor 1).

NR4A3_MOUSE
θ value	1.08415e-162 (rank : 3)	NC score	0.994897 (rank : 4)
Query Neighborhood Hits	120	Target Neighborhood Hits	127	Shared Neighborhood Hits	95
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

NR4A3_HUMAN
θ value	2.04462e-161 (rank : 4)	NC score	0.995011 (rank : 3)
Query Neighborhood Hits	120	Target Neighborhood Hits	131	Shared Neighborhood Hits	94
SwissProt Accessions	Q92570, Q12935, Q14979, Q16420, Q4VXA9, Q9UEK2, Q9UEK3	Gene names	NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1) (Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphan receptor).

NR4A1_HUMAN
θ value	9.49765e-159 (rank : 5)	NC score	0.993346 (rank : 6)
Query Neighborhood Hits	120	Target Neighborhood Hits	133	Shared Neighborhood Hits	94
SwissProt Accessions	P22736	Gene names	NR4A1, GFRP1, HMR, NAK1
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Early response protein NAK1) (TR3 orphan receptor) (ST-59).

NR4A1_MOUSE
θ value	1.37464e-149 (rank : 6)	NC score	0.993561 (rank : 5)
Query Neighborhood Hits	120	Target Neighborhood Hits	128	Shared Neighborhood Hits	94
SwissProt Accessions	P12813	Gene names	Nr4a1, Gfrp, Hmr, N10, Nur77
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Nuclear hormone receptor NUR/77) (N10 nuclear protein).

RARB_MOUSE
θ value	2.75849e-49 (rank : 7)	NC score	0.955129 (rank : 7)
Query Neighborhood Hits	120	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	P22605, P11417, P22604	Gene names	Rarb, Nr1b2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta).

RARA_HUMAN
θ value	1.36902e-48 (rank : 8)	NC score	0.954575 (rank : 13)
Query Neighborhood Hits	120	Target Neighborhood Hits	118	Shared Neighborhood Hits	94
SwissProt Accessions	P10276, P78456, Q13440, Q13441, Q9NQS0	Gene names	RARA, NR1B1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARG1_MOUSE
θ value	1.36902e-48 (rank : 9)	NC score	0.954558 (rank : 14)
Query Neighborhood Hits	120	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

RARG1_HUMAN
θ value	1.788e-48 (rank : 10)	NC score	0.954776 (rank : 9)
Query Neighborhood Hits	120	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARB_HUMAN
θ value	2.3352e-48 (rank : 11)	NC score	0.954749 (rank : 10)
Query Neighborhood Hits	120	Target Neighborhood Hits	118	Shared Neighborhood Hits	94
SwissProt Accessions	P10826, P12891, Q00989, Q15298, Q9UN48	Gene names	RARB, HAP, NR1B2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta) (RAR-epsilon) (HBV-activated protein).

RARA_MOUSE
θ value	3.04986e-48 (rank : 12)	NC score	0.954610 (rank : 12)
Query Neighborhood Hits	120	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P11416, P22603	Gene names	Rara, Nr1b1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARG2_HUMAN
θ value	6.7944e-48 (rank : 13)	NC score	0.954822 (rank : 8)
Query Neighborhood Hits	120	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

RARG2_MOUSE
θ value	8.87376e-48 (rank : 14)	NC score	0.954691 (rank : 11)
Query Neighborhood Hits	120	Target Neighborhood Hits	114	Shared Neighborhood Hits	94
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

ERR3_HUMAN
θ value	2.58187e-47 (rank : 15)	NC score	0.953269 (rank : 15)
Query Neighborhood Hits	120	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P62508, O75454, O96021, Q68DA0, Q6P274, Q6PK28, Q6TS38, Q9R1F3, Q9UNJ4	Gene names	ESRRG, ERR3, ERRG2, KIAA0832, NR3B3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (ERR gamma-2).

ERR3_MOUSE
θ value	2.58187e-47 (rank : 16)	NC score	0.953269 (rank : 16)
Query Neighborhood Hits	120	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P62509, O75454, O96021, Q8CHC9, Q9R1F3	Gene names	Esrrg, Err3, Kiaa0832, Nr3b3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3).

RXRA_HUMAN
θ value	1.41672e-45 (rank : 17)	NC score	0.944823 (rank : 23)
Query Neighborhood Hits	120	Target Neighborhood Hits	223	Shared Neighborhood Hits	96
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

RXRA_MOUSE
θ value	2.41655e-45 (rank : 18)	NC score	0.947393 (rank : 22)
Query Neighborhood Hits	120	Target Neighborhood Hits	129	Shared Neighborhood Hits	95
SwissProt Accessions	P28700	Gene names	Rxra, Nr2b1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

RXRB_HUMAN
θ value	7.77379e-44 (rank : 19)	NC score	0.940062 (rank : 26)
Query Neighborhood Hits	120	Target Neighborhood Hits	280	Shared Neighborhood Hits	99
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

ERR2_HUMAN
θ value	2.26182e-43 (rank : 20)	NC score	0.951439 (rank : 18)
Query Neighborhood Hits	120	Target Neighborhood Hits	108	Shared Neighborhood Hits	94
SwissProt Accessions	O95718, Q9HCB4	Gene names	ESRRB, ERRB2, NR3B2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2) (ERR beta-2).

RXRB_MOUSE
θ value	2.95404e-43 (rank : 21)	NC score	0.943120 (rank : 24)
Query Neighborhood Hits	120	Target Neighborhood Hits	230	Shared Neighborhood Hits	99
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

ERR2_MOUSE
θ value	5.03882e-43 (rank : 22)	NC score	0.951807 (rank : 17)
Query Neighborhood Hits	120	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	Q61539, O09067, O09146	Gene names	Esrrb, Err-2, Err2, Nr3b2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2).

RXRG_HUMAN
θ value	1.46607e-42 (rank : 23)	NC score	0.948174 (rank : 21)
Query Neighborhood Hits	120	Target Neighborhood Hits	114	Shared Neighborhood Hits	95
SwissProt Accessions	P48443	Gene names	RXRG, NR2B3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

COT2_HUMAN
θ value	1.91475e-42 (rank : 24)	NC score	0.939601 (rank : 31)
Query Neighborhood Hits	120	Target Neighborhood Hits	135	Shared Neighborhood Hits	97
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT2_MOUSE
θ value	1.91475e-42 (rank : 25)	NC score	0.939601 (rank : 32)
Query Neighborhood Hits	120	Target Neighborhood Hits	135	Shared Neighborhood Hits	97
SwissProt Accessions	P43135	Gene names	Nr2f2, Aporp1, Arp-1, Arp1, Tfcoup2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

RXRG_MOUSE
θ value	1.91475e-42 (rank : 26)	NC score	0.948378 (rank : 20)
Query Neighborhood Hits	120	Target Neighborhood Hits	113	Shared Neighborhood Hits	95
SwissProt Accessions	P28705	Gene names	Rxrg, Nr2b3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

COT1_HUMAN
θ value	5.57106e-42 (rank : 27)	NC score	0.938875 (rank : 35)
Query Neighborhood Hits	120	Target Neighborhood Hits	159	Shared Neighborhood Hits	99
SwissProt Accessions	P10589	Gene names	NR2F1, EAR3, ERBAL3, TFCOUP1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I) (V-ERBA-related protein EAR-3).

COT1_MOUSE
θ value	5.57106e-42 (rank : 28)	NC score	0.938994 (rank : 34)
Query Neighborhood Hits	120	Target Neighborhood Hits	160	Shared Neighborhood Hits	98
SwissProt Accessions	Q60632, Q61438	Gene names	Nr2f1, Erbal3, Tfcoup1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I).

ERR1_HUMAN
θ value	1.08726e-37 (rank : 29)	NC score	0.951427 (rank : 19)
Query Neighborhood Hits	120	Target Neighborhood Hits	157	Shared Neighborhood Hits	94
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

EAR2_MOUSE
θ value	9.20422e-37 (rank : 30)	NC score	0.938807 (rank : 36)
Query Neighborhood Hits	120	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	P43136, Q61504	Gene names	Nr2f6, Ear-2, Ear2, Erbal2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

ESR1_MOUSE
θ value	5.96599e-36 (rank : 31)	NC score	0.939833 (rank : 29)
Query Neighborhood Hits	120	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	P19785, Q9JJT5, Q9QY51, Q9QY52	Gene names	Esr1, Esr, Estr, Estra, Nr3a1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

ESR1_HUMAN
θ value	7.79185e-36 (rank : 32)	NC score	0.939069 (rank : 33)
Query Neighborhood Hits	120	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P03372, Q13511, Q14276, Q9NU51, Q9UDZ7, Q9UIS7	Gene names	ESR1, ESR, NR3A1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

NR1H3_MOUSE
θ value	7.79185e-36 (rank : 33)	NC score	0.939978 (rank : 28)
Query Neighborhood Hits	120	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Z0Y9, Q9QUH7	Gene names	Nr1h3, Lxra
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

EAR2_HUMAN
θ value	1.01765e-35 (rank : 34)	NC score	0.938337 (rank : 37)
Query Neighborhood Hits	120	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P10588, Q9BUE8	Gene names	NR2F6, EAR2, ERBAL2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

THA_MOUSE
θ value	1.32909e-35 (rank : 35)	NC score	0.934670 (rank : 42)
Query Neighborhood Hits	120	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P63058, P10685, P15827, P16416, P37241, Q63107, Q63195, Q63196, Q99146	Gene names	Thra, C-erba-alpha, Nr1a1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1).

THA_HUMAN
θ value	1.73584e-35 (rank : 36)	NC score	0.934551 (rank : 43)
Query Neighborhood Hits	120	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P10827, P21205, Q8N6A1, Q96H73	Gene names	THRA, ERBA1, NR1A1, THRA1
Domain Architecture
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1) (EAR-7) (EAR7).

THB1_HUMAN
θ value	8.61488e-35 (rank : 37)	NC score	0.928326 (rank : 53)
Query Neighborhood Hits	120	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P10828, Q13986	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture
Description	Thyroid hormone receptor beta-1.

NR1H3_HUMAN
θ value	1.12514e-34 (rank : 38)	NC score	0.939993 (rank : 27)
Query Neighborhood Hits	120	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	Q13133, Q96H87	Gene names	NR1H3, LXRA
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

HNF4G_HUMAN
θ value	1.9192e-34 (rank : 39)	NC score	0.940421 (rank : 25)
Query Neighborhood Hits	120	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q14541, Q9UH81, Q9UIS6	Gene names	HNF4G, NR2A2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

THB2_MOUSE
θ value	1.9192e-34 (rank : 40)	NC score	0.927567 (rank : 55)
Query Neighborhood Hits	120	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P37244	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-2.

THB2_HUMAN
θ value	3.27365e-34 (rank : 41)	NC score	0.928448 (rank : 52)
Query Neighborhood Hits	120	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	P37243	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor beta-2.

THB1_MOUSE
θ value	5.584e-34 (rank : 42)	NC score	0.927446 (rank : 56)
Query Neighborhood Hits	120	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P37242	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-1.

HNF4A_HUMAN
θ value	2.12192e-33 (rank : 43)	NC score	0.938114 (rank : 38)
Query Neighborhood Hits	120	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P41235, O00659, O00723, Q14540, Q92653, Q92654, Q92655, Q99864, Q9NQH0	Gene names	HNF4A, HNF4, NR2A1, TCF14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

ESR2_HUMAN
θ value	3.61944e-33 (rank : 44)	NC score	0.937903 (rank : 39)
Query Neighborhood Hits	120	Target Neighborhood Hits	110	Shared Neighborhood Hits	94
SwissProt Accessions	Q92731, O60608, O60685, O60702, O60703, O75583, O75584, Q86Z31, Q9UEV6, Q9UHD3, Q9UQK9	Gene names	ESR2, ESTRB, NR3A2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

HNF4G_MOUSE
θ value	1.0531e-32 (rank : 45)	NC score	0.939655 (rank : 30)
Query Neighborhood Hits	120	Target Neighborhood Hits	101	Shared Neighborhood Hits	94
SwissProt Accessions	Q9WUU6	Gene names	Hnf4g, Nr2a2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

ESR2_MOUSE
θ value	1.37539e-32 (rank : 46)	NC score	0.936926 (rank : 41)
Query Neighborhood Hits	120	Target Neighborhood Hits	110	Shared Neighborhood Hits	94
SwissProt Accessions	O08537, O35635, O70519	Gene names	Esr2, Estrb, Nr3a2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

HNF4A_MOUSE
θ value	4.42448e-31 (rank : 47)	NC score	0.937524 (rank : 40)
Query Neighborhood Hits	120	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P49698	Gene names	Hnf4a, Hnf-4, Hnf4, Nr2a1, Tcf14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

NR2E1_MOUSE
θ value	9.2256e-29 (rank : 48)	NC score	0.933375 (rank : 45)
Query Neighborhood Hits	120	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	Q64104	Gene names	Nr2e1, Tll, Tlx
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (mTll).

NR2E3_HUMAN
θ value	3.50572e-28 (rank : 49)	NC score	0.932401 (rank : 49)
Query Neighborhood Hits	120	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y5X4, Q9UHM4	Gene names	NR2E3, PNR, RNR
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

NR2E3_MOUSE
θ value	4.57862e-28 (rank : 50)	NC score	0.933182 (rank : 46)
Query Neighborhood Hits	120	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QXZ7	Gene names	Nr2e3, Pnr, Rnr
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

NR2E1_HUMAN
θ value	5.97985e-28 (rank : 51)	NC score	0.932003 (rank : 50)
Query Neighborhood Hits	120	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y466	Gene names	NR2E1, TLX
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (hTll).

NR5A2_HUMAN
θ value	1.33217e-27 (rank : 52)	NC score	0.915217 (rank : 70)
Query Neighborhood Hits	120	Target Neighborhood Hits	112	Shared Neighborhood Hits	94
SwissProt Accessions	O00482, O95642	Gene names	NR5A2, B1F, CPF, FTF
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Alpha-1-fetoprotein transcription factor) (Hepatocytic transcription factor) (B1-binding factor) (hB1F) (CYP7A promoter-binding factor) (Liver receptor homolog 1) (LRH-1).

NR1I3_MOUSE
θ value	1.73987e-27 (rank : 53)	NC score	0.933990 (rank : 44)
Query Neighborhood Hits	120	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	O35627, O35628	Gene names	Nr1i3, Car
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67).

NR1H4_HUMAN
θ value	2.27234e-27 (rank : 54)	NC score	0.933047 (rank : 47)
Query Neighborhood Hits	120	Target Neighborhood Hits	112	Shared Neighborhood Hits	94
SwissProt Accessions	Q96RI1, Q8NFP5, Q8NFP6, Q92943	Gene names	NR1H4, BAR, FXR, HRR1, RIP14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

NR1H4_MOUSE
θ value	3.87602e-27 (rank : 55)	NC score	0.932547 (rank : 48)
Query Neighborhood Hits	120	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	Q60641, Q60642, Q60643	Gene names	Nr1h4, Bar, Fxr, Rip14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

NR1H2_MOUSE
θ value	8.63488e-27 (rank : 56)	NC score	0.928268 (rank : 54)
Query Neighborhood Hits	120	Target Neighborhood Hits	109	Shared Neighborhood Hits	95
SwissProt Accessions	Q60644	Gene names	Nr1h2, Lxrb, Rip15, Unr, Unr2
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Retinoid X receptor-interacting protein No.15).

PPARD_HUMAN
θ value	8.63488e-27 (rank : 57)	NC score	0.919549 (rank : 62)
Query Neighborhood Hits	120	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q03181, Q7Z5K0, Q9BUD4	Gene names	PPARD, NR1C2, PPARB
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1) (NUCI).

PPARD_MOUSE
θ value	2.51237e-26 (rank : 58)	NC score	0.918761 (rank : 65)
Query Neighborhood Hits	120	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P35396, P37239	Gene names	Ppard, Nr1c2, Pparb
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1).

PPARG_HUMAN
θ value	3.28125e-26 (rank : 59)	NC score	0.917675 (rank : 67)
Query Neighborhood Hits	120	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37231, O00684, O00710, O14515, Q15178, Q15179, Q15180, Q15832, Q86U60, Q96J12	Gene names	PPARG, NR1C3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

PPARG_MOUSE
θ value	5.59698e-26 (rank : 60)	NC score	0.917538 (rank : 68)
Query Neighborhood Hits	120	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37238	Gene names	Pparg, Nr1c3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

NR5A2_MOUSE
θ value	7.30988e-26 (rank : 61)	NC score	0.915002 (rank : 72)
Query Neighborhood Hits	120	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	P45448	Gene names	Nr5a2, Lrh1
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Liver receptor homolog 1) (LRH-1).

PPARA_MOUSE
θ value	1.24688e-25 (rank : 62)	NC score	0.919341 (rank : 63)
Query Neighborhood Hits	120	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	P23204	Gene names	Ppara, Nr1c1, Ppar
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

GCR_HUMAN
θ value	2.12685e-25 (rank : 63)	NC score	0.886442 (rank : 87)
Query Neighborhood Hits	120	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P04150, P04151, Q53EP5, Q6N0A4	Gene names	NR3C1, GRL
Domain Architecture
Description	Glucocorticoid receptor (GR).

PPARA_HUMAN
θ value	2.77775e-25 (rank : 64)	NC score	0.918517 (rank : 66)
Query Neighborhood Hits	120	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q07869, Q16241, Q92486, Q92689, Q9Y3N1	Gene names	PPARA, NR1C1, PPAR
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

VDR_MOUSE
θ value	6.18819e-25 (rank : 65)	NC score	0.916105 (rank : 69)
Query Neighborhood Hits	120	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P48281	Gene names	Vdr, Nr1i1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

STF1_HUMAN
θ value	1.05554e-24 (rank : 66)	NC score	0.922009 (rank : 57)
Query Neighborhood Hits	120	Target Neighborhood Hits	132	Shared Neighborhood Hits	95
SwissProt Accessions	Q13285, O15196	Gene names	NR5A1, AD4BP, FTZF1, SF1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1).

STF1_MOUSE
θ value	1.05554e-24 (rank : 67)	NC score	0.921195 (rank : 60)
Query Neighborhood Hits	120	Target Neighborhood Hits	137	Shared Neighborhood Hits	94
SwissProt Accessions	P33242	Gene names	Nr5a1, Ftzf1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1) (Embryonal LTR-binding protein) (ELP) (Embryonal long terminal repeat- binding protein) (Steroid hydroxylase positive regulator).

GCR_MOUSE
θ value	5.23862e-24 (rank : 68)	NC score	0.881793 (rank : 88)
Query Neighborhood Hits	120	Target Neighborhood Hits	117	Shared Neighborhood Hits	95
SwissProt Accessions	P06537, Q61628, Q61629	Gene names	Nr3c1, Grl, Grl1
Domain Architecture
Description	Glucocorticoid receptor (GR).

TR2_HUMAN
θ value	1.16704e-23 (rank : 69)	NC score	0.919087 (rank : 64)
Query Neighborhood Hits	120	Target Neighborhood Hits	110	Shared Neighborhood Hits	94
SwissProt Accessions	P13056	Gene names	NR2C1, TR2
Domain Architecture
Description	Orphan nuclear receptor TR2 (Testicular receptor 2).

TR2_MOUSE
θ value	3.39556e-23 (rank : 70)	NC score	0.904153 (rank : 78)
Query Neighborhood Hits	120	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q505F1, P97763, Q3UIJ7, Q4U1Z4, Q60927, Q62152, Q8VIJ3	Gene names	Nr2c1, Tr2, Tr2-11
Domain Architecture	No domain graphic available
Description	Orphan nuclear receptor TR2 (Testicular receptor 2) (mTR2).

NR1D2_MOUSE
θ value	5.79196e-23 (rank : 71)	NC score	0.912204 (rank : 76)
Query Neighborhood Hits	120	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	Q60674, Q60646	Gene names	Nr1d2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (Orphan nuclear receptor RVR).

MCR_HUMAN
θ value	9.87957e-23 (rank : 72)	NC score	0.878890 (rank : 90)
Query Neighborhood Hits	120	Target Neighborhood Hits	149	Shared Neighborhood Hits	96
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

NR1D2_HUMAN
θ value	1.29031e-22 (rank : 73)	NC score	0.914608 (rank : 73)
Query Neighborhood Hits	120	Target Neighborhood Hits	115	Shared Neighborhood Hits	94
SwissProt Accessions	Q14995, O00402, Q86XD4	Gene names	NR1D2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (EAR-1R) (Orphan nuclear hormone receptor BD73).

NR1D1_HUMAN
θ value	2.87452e-22 (rank : 74)	NC score	0.920260 (rank : 61)
Query Neighborhood Hits	120	Target Neighborhood Hits	140	Shared Neighborhood Hits	95
SwissProt Accessions	P20393, Q15304	Gene names	NR1D1, EAR1, HREV, THRAL
Domain Architecture
Description	Orphan nuclear receptor NR1D1 (V-erbA-related protein EAR-1) (Rev- erbA-alpha).

RORA_HUMAN
θ value	2.87452e-22 (rank : 75)	NC score	0.900750 (rank : 80)
Query Neighborhood Hits	120	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P35398, P35397, P35399, P45445, Q96H83	Gene names	RORA, NR1F1, RZRA
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

RORA_MOUSE
θ value	2.87452e-22 (rank : 76)	NC score	0.899985 (rank : 83)
Query Neighborhood Hits	120	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P51448, P70283, P97741, P97773, Q923G1	Gene names	Rora, Nr1f1, Rzra
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

PXR_HUMAN
θ value	4.9032e-22 (rank : 77)	NC score	0.915062 (rank : 71)
Query Neighborhood Hits	120	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	O75469, Q96AC7, Q9UJ22, Q9UJ23, Q9UJ24, Q9UJ25, Q9UJ26, Q9UJ27	Gene names	NR1I2, PXR
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor) (Orphan nuclear receptor PAR1) (Steroid and xenobiotic receptor) (SXR).

RORG_HUMAN
θ value	4.9032e-22 (rank : 78)	NC score	0.898982 (rank : 84)
Query Neighborhood Hits	120	Target Neighborhood Hits	119	Shared Neighborhood Hits	94
SwissProt Accessions	P51449, Q8N5V7, Q8NCY8	Gene names	RORC, NR1F3, RORG, RZRG
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma).

RORG_MOUSE
θ value	4.9032e-22 (rank : 79)	NC score	0.903048 (rank : 79)
Query Neighborhood Hits	120	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	P51450, Q61027, Q91YT5, Q9QXD9, Q9R177	Gene names	Rorc, Nr1f3, Rorg, Thor
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma) (Thymus orphan receptor) (TOR).

RORB_HUMAN
θ value	8.36355e-22 (rank : 80)	NC score	0.900298 (rank : 82)
Query Neighborhood Hits	120	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	Q92753, Q8WX73	Gene names	RORB, NR1F2, RZRB
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORB_MOUSE
θ value	8.36355e-22 (rank : 81)	NC score	0.900549 (rank : 81)
Query Neighborhood Hits	120	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	Q8R1B8	Gene names	Rorb, Nr1f2
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

NR1I3_HUMAN
θ value	1.09232e-21 (rank : 82)	NC score	0.929428 (rank : 51)
Query Neighborhood Hits	120	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	Q14994	Gene names	NR1I3, CAR
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Constitutive activator of retinoid response) (Constitutive active response) (Orphan nuclear receptor MB67).

TR4_HUMAN
θ value	1.09232e-21 (rank : 83)	NC score	0.898680 (rank : 85)
Query Neighborhood Hits	120	Target Neighborhood Hits	117	Shared Neighborhood Hits	94
SwissProt Accessions	P49116, P55092	Gene names	NR2C2, TAK1, TR4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

NR6A1_HUMAN
θ value	2.43343e-21 (rank : 84)	NC score	0.921947 (rank : 58)
Query Neighborhood Hits	120	Target Neighborhood Hits	108	Shared Neighborhood Hits	94
SwissProt Accessions	Q15406, O00551, O00603, Q8NHQ0, Q92898, Q99802	Gene names	NR6A1, GCNF
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

NR6A1_MOUSE
θ value	2.43343e-21 (rank : 85)	NC score	0.921563 (rank : 59)
Query Neighborhood Hits	120	Target Neighborhood Hits	110	Shared Neighborhood Hits	94
SwissProt Accessions	Q64249	Gene names	Nr6a1, Gcnf
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

ANDR_MOUSE
θ value	4.15078e-21 (rank : 86)	NC score	0.879756 (rank : 89)
Query Neighborhood Hits	120	Target Neighborhood Hits	133	Shared Neighborhood Hits	96
SwissProt Accessions	P19091	Gene names	Ar, Nr3c4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

TR4_MOUSE
θ value	4.15078e-21 (rank : 87)	NC score	0.897749 (rank : 86)
Query Neighborhood Hits	120	Target Neighborhood Hits	115	Shared Neighborhood Hits	94
SwissProt Accessions	P49117, P55093	Gene names	Nr2c2, Mtr2r1, Tak1, Tr4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

MCR_MOUSE
θ value	9.24701e-21 (rank : 88)	NC score	0.875010 (rank : 92)
Query Neighborhood Hits	120	Target Neighborhood Hits	162	Shared Neighborhood Hits	96
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

PRGR_MOUSE
θ value	2.69047e-20 (rank : 89)	NC score	0.865815 (rank : 94)
Query Neighborhood Hits	120	Target Neighborhood Hits	286	Shared Neighborhood Hits	95
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

PXR_MOUSE
θ value	1.33526e-19 (rank : 90)	NC score	0.912837 (rank : 75)
Query Neighborhood Hits	120	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	O54915	Gene names	Nr1i2, Pxr
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor).

PRGR_HUMAN
θ value	8.65492e-19 (rank : 91)	NC score	0.870641 (rank : 93)
Query Neighborhood Hits	120	Target Neighborhood Hits	163	Shared Neighborhood Hits	96
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

ANDR_HUMAN
θ value	1.13037e-18 (rank : 92)	NC score	0.876745 (rank : 91)
Query Neighborhood Hits	120	Target Neighborhood Hits	126	Shared Neighborhood Hits	96
SwissProt Accessions	P10275	Gene names	AR, DHTR, NR3C4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

VDR_HUMAN
θ value	4.29542e-18 (rank : 93)	NC score	0.912044 (rank : 77)
Query Neighborhood Hits	120	Target Neighborhood Hits	112	Shared Neighborhood Hits	94
SwissProt Accessions	P11473	Gene names	VDR, NR1I1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

NR1H2_HUMAN
θ value	1.38178e-16 (rank : 94)	NC score	0.914202 (rank : 74)
Query Neighborhood Hits	120	Target Neighborhood Hits	114	Shared Neighborhood Hits	94
SwissProt Accessions	P55055, Q12970	Gene names	NR1H2, LXRB, NER, UNR
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Nuclear receptor NER).

CO5A3_HUMAN
θ value	0.21417 (rank : 95)	NC score	0.013042 (rank : 102)
Query Neighborhood Hits	120	Target Neighborhood Hits	433	Shared Neighborhood Hits	13
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

CO4A5_HUMAN
θ value	0.279714 (rank : 96)	NC score	0.017450 (rank : 100)
Query Neighborhood Hits	120	Target Neighborhood Hits	383	Shared Neighborhood Hits	15
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

DAP1_HUMAN
θ value	0.47712 (rank : 97)	NC score	0.037391 (rank : 99)
Query Neighborhood Hits	120	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	P51397, Q9BUC9	Gene names	DAP, DAP1
Domain Architecture	No domain graphic available
Description	Death-associated protein 1 (DAP-1).

CO4A2_MOUSE
θ value	1.06291 (rank : 98)	NC score	0.010483 (rank : 108)
Query Neighborhood Hits	120	Target Neighborhood Hits	492	Shared Neighborhood Hits	16
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

ADAM8_HUMAN
θ value	1.38821 (rank : 99)	NC score	0.001712 (rank : 121)
Query Neighborhood Hits	120	Target Neighborhood Hits	327	Shared Neighborhood Hits	4
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

DACH1_MOUSE
θ value	1.38821 (rank : 100)	NC score	0.011139 (rank : 106)
Query Neighborhood Hits	120	Target Neighborhood Hits	228	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QYB2, O88716, Q8BPQ0, Q8C8D7, Q9QY47, Q9R218, Q9Z0Y5	Gene names	Dach1, Dach
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

A2MG_HUMAN
θ value	1.81305 (rank : 101)	NC score	0.004603 (rank : 118)
Query Neighborhood Hits	120	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	P01023, Q13677, Q59F47, Q5QTS0, Q68DN2, Q6PIY3, Q6PN97	Gene names	A2M
Domain Architecture
Description	Alpha-2-macroglobulin precursor (Alpha-2-M).

CO4A4_HUMAN
θ value	1.81305 (rank : 102)	NC score	0.011160 (rank : 105)
Query Neighborhood Hits	120	Target Neighborhood Hits	440	Shared Neighborhood Hits	14
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

COJA1_HUMAN
θ value	1.81305 (rank : 103)	NC score	0.009897 (rank : 109)
Query Neighborhood Hits	120	Target Neighborhood Hits	323	Shared Neighborhood Hits	10
SwissProt Accessions	Q14993, Q00559, Q05850, Q12885, Q13676, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2	Gene names	COL19A1
Domain Architecture
Description	Collagen alpha-1(XIX) chain precursor (Collagen alpha-1(Y) chain).

HGS_HUMAN
θ value	1.81305 (rank : 104)	NC score	0.008494 (rank : 110)
Query Neighborhood Hits	120	Target Neighborhood Hits	517	Shared Neighborhood Hits	8
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HGS_MOUSE
θ value	2.36792 (rank : 105)	NC score	0.007910 (rank : 111)
Query Neighborhood Hits	120	Target Neighborhood Hits	589	Shared Neighborhood Hits	9
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

CA043_HUMAN
θ value	4.03905 (rank : 106)	NC score	0.014567 (rank : 101)
Query Neighborhood Hits	120	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BWL3, Q5M801, Q5VU73, Q5VU83, Q96HP7, Q9UFU2, Q9UGL7, Q9UGL8, Q9Y2R6	Gene names	C1orf43, NICE3, NS5ATP4
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf43 (Hepatitis C virus NS5A-transactivated protein 4) (Protein NICE-3) (S863-3).

GRLF1_HUMAN
θ value	4.03905 (rank : 107)	NC score	0.003187 (rank : 119)
Query Neighborhood Hits	120	Target Neighborhood Hits	167	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

IF4G1_HUMAN
θ value	4.03905 (rank : 108)	NC score	0.004638 (rank : 117)
Query Neighborhood Hits	120	Target Neighborhood Hits	347	Shared Neighborhood Hits	6
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

MAML1_HUMAN
θ value	4.03905 (rank : 109)	NC score	0.010677 (rank : 107)
Query Neighborhood Hits	120	Target Neighborhood Hits	228	Shared Neighborhood Hits	9
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

R3HD2_MOUSE
θ value	4.03905 (rank : 110)	NC score	0.007803 (rank : 112)
Query Neighborhood Hits	120	Target Neighborhood Hits	397	Shared Neighborhood Hits	10
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

CMTA1_HUMAN
θ value	5.27518 (rank : 111)	NC score	0.007087 (rank : 114)
Query Neighborhood Hits	120	Target Neighborhood Hits	217	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

NCOA6_MOUSE
θ value	5.27518 (rank : 112)	NC score	0.012998 (rank : 103)
Query Neighborhood Hits	120	Target Neighborhood Hits	1076	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

SMBT1_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.002699 (rank : 120)
Query Neighborhood Hits	120	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UHJ3, Q96C73, Q9Y4Q9	Gene names	SFMBT1, RU1
Domain Architecture	No domain graphic available
Description	Scm-like with four MBT domains protein 1 (Renal ubiquitous protein 1).

4ET_HUMAN
θ value	6.88961 (rank : 114)	NC score	0.006950 (rank : 115)
Query Neighborhood Hits	120	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRA8, Q8NCF2, Q9H708	Gene names	EIF4ENIF1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

NCOA6_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.011638 (rank : 104)
Query Neighborhood Hits	120	Target Neighborhood Hits	1202	Shared Neighborhood Hits	25
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

CBP_HUMAN
θ value	8.99809 (rank : 116)	NC score	0.004980 (rank : 116)
Query Neighborhood Hits	120	Target Neighborhood Hits	941	Shared Neighborhood Hits	14
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

GLI2_HUMAN
θ value	8.99809 (rank : 117)	NC score	-0.006168 (rank : 124)
Query Neighborhood Hits	120	Target Neighborhood Hits	971	Shared Neighborhood Hits	12
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

MAML1_MOUSE
θ value	8.99809 (rank : 118)	NC score	0.007538 (rank : 113)
Query Neighborhood Hits	120	Target Neighborhood Hits	279	Shared Neighborhood Hits	12
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

SSH1_HUMAN
θ value	8.99809 (rank : 119)	NC score	0.001249 (rank : 122)
Query Neighborhood Hits	120	Target Neighborhood Hits	164	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).

TENX_HUMAN
θ value	8.99809 (rank : 120)	NC score	-0.003543 (rank : 123)
Query Neighborhood Hits	120	Target Neighborhood Hits	789	Shared Neighborhood Hits	8
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

DAX1_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.404753 (rank : 98)
Query Neighborhood Hits	120	Target Neighborhood Hits	65	Shared Neighborhood Hits	55
SwissProt Accessions	P51843, Q96F69	Gene names	NR0B1, AHC, DAX1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1) (DSS-AHC critical region on the X chromosome protein 1).

DAX1_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.435795 (rank : 96)
Query Neighborhood Hits	120	Target Neighborhood Hits	70	Shared Neighborhood Hits	56
SwissProt Accessions	Q61066, O09068, O09147	Gene names	Nr0b1, Ahch, Dax1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1).

SHP_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.443577 (rank : 95)
Query Neighborhood Hits	120	Target Neighborhood Hits	57	Shared Neighborhood Hits	52
SwissProt Accessions	Q15466, Q5QP36	Gene names	NR0B2, SHP
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

SHP_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.433624 (rank : 97)
Query Neighborhood Hits	120	Target Neighborhood Hits	53	Shared Neighborhood Hits	49
SwissProt Accessions	Q62227, Q53Z53	Gene names	Nr0b2, Shp
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

Hits sorted by NC score

NR4A2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	120	Target Neighborhood Hits	120	Shared Neighborhood Hits	120
SwissProt Accessions	P43354, Q16311	Gene names	NR4A2, NOT, NURR1, TINUR
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (Immediate-early response protein NOT) (Transcriptionally-inducible nuclear receptor).

NR4A2_MOUSE
NC score	0.999888 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	120	Target Neighborhood Hits	121	Shared Neighborhood Hits	118
SwissProt Accessions	Q06219, O08690	Gene names	Nr4a2, Nurr1
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (NUR- related factor 1).

NR4A3_HUMAN
NC score	0.995011 (rank : 3)	θ value	2.04462e-161 (rank : 4)
Query Neighborhood Hits	120	Target Neighborhood Hits	131	Shared Neighborhood Hits	94
SwissProt Accessions	Q92570, Q12935, Q14979, Q16420, Q4VXA9, Q9UEK2, Q9UEK3	Gene names	NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1) (Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphan receptor).

NR4A3_MOUSE
NC score	0.994897 (rank : 4)	θ value	1.08415e-162 (rank : 3)
Query Neighborhood Hits	120	Target Neighborhood Hits	127	Shared Neighborhood Hits	95
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

NR4A1_MOUSE
NC score	0.993561 (rank : 5)	θ value	1.37464e-149 (rank : 6)
Query Neighborhood Hits	120	Target Neighborhood Hits	128	Shared Neighborhood Hits	94
SwissProt Accessions	P12813	Gene names	Nr4a1, Gfrp, Hmr, N10, Nur77
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Nuclear hormone receptor NUR/77) (N10 nuclear protein).

NR4A1_HUMAN
NC score	0.993346 (rank : 6)	θ value	9.49765e-159 (rank : 5)
Query Neighborhood Hits	120	Target Neighborhood Hits	133	Shared Neighborhood Hits	94
SwissProt Accessions	P22736	Gene names	NR4A1, GFRP1, HMR, NAK1
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Early response protein NAK1) (TR3 orphan receptor) (ST-59).

RARB_MOUSE
NC score	0.955129 (rank : 7)	θ value	2.75849e-49 (rank : 7)
Query Neighborhood Hits	120	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	P22605, P11417, P22604	Gene names	Rarb, Nr1b2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta).

RARG2_HUMAN
NC score	0.954822 (rank : 8)	θ value	6.7944e-48 (rank : 13)
Query Neighborhood Hits	120	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

RARG1_HUMAN
NC score	0.954776 (rank : 9)	θ value	1.788e-48 (rank : 10)
Query Neighborhood Hits	120	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARB_HUMAN
NC score	0.954749 (rank : 10)	θ value	2.3352e-48 (rank : 11)
Query Neighborhood Hits	120	Target Neighborhood Hits	118	Shared Neighborhood Hits	94
SwissProt Accessions	P10826, P12891, Q00989, Q15298, Q9UN48	Gene names	RARB, HAP, NR1B2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta) (RAR-epsilon) (HBV-activated protein).

RARG2_MOUSE
NC score	0.954691 (rank : 11)	θ value	8.87376e-48 (rank : 14)
Query Neighborhood Hits	120	Target Neighborhood Hits	114	Shared Neighborhood Hits	94
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

RARA_MOUSE
NC score	0.954610 (rank : 12)	θ value	3.04986e-48 (rank : 12)
Query Neighborhood Hits	120	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P11416, P22603	Gene names	Rara, Nr1b1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARA_HUMAN
NC score	0.954575 (rank : 13)	θ value	1.36902e-48 (rank : 8)
Query Neighborhood Hits	120	Target Neighborhood Hits	118	Shared Neighborhood Hits	94
SwissProt Accessions	P10276, P78456, Q13440, Q13441, Q9NQS0	Gene names	RARA, NR1B1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARG1_MOUSE
NC score	0.954558 (rank : 14)	θ value	1.36902e-48 (rank : 9)
Query Neighborhood Hits	120	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

ERR3_HUMAN
NC score	0.953269 (rank : 15)	θ value	2.58187e-47 (rank : 15)
Query Neighborhood Hits	120	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P62508, O75454, O96021, Q68DA0, Q6P274, Q6PK28, Q6TS38, Q9R1F3, Q9UNJ4	Gene names	ESRRG, ERR3, ERRG2, KIAA0832, NR3B3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (ERR gamma-2).

ERR3_MOUSE
NC score	0.953269 (rank : 16)	θ value	2.58187e-47 (rank : 16)
Query Neighborhood Hits	120	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P62509, O75454, O96021, Q8CHC9, Q9R1F3	Gene names	Esrrg, Err3, Kiaa0832, Nr3b3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3).

ERR2_MOUSE
NC score	0.951807 (rank : 17)	θ value	5.03882e-43 (rank : 22)
Query Neighborhood Hits	120	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	Q61539, O09067, O09146	Gene names	Esrrb, Err-2, Err2, Nr3b2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2).

ERR2_HUMAN
NC score	0.951439 (rank : 18)	θ value	2.26182e-43 (rank : 20)
Query Neighborhood Hits	120	Target Neighborhood Hits	108	Shared Neighborhood Hits	94
SwissProt Accessions	O95718, Q9HCB4	Gene names	ESRRB, ERRB2, NR3B2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2) (ERR beta-2).

ERR1_HUMAN
NC score	0.951427 (rank : 19)	θ value	1.08726e-37 (rank : 29)
Query Neighborhood Hits	120	Target Neighborhood Hits	157	Shared Neighborhood Hits	94
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

RXRG_MOUSE
NC score	0.948378 (rank : 20)	θ value	1.91475e-42 (rank : 26)
Query Neighborhood Hits	120	Target Neighborhood Hits	113	Shared Neighborhood Hits	95
SwissProt Accessions	P28705	Gene names	Rxrg, Nr2b3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

RXRG_HUMAN
NC score	0.948174 (rank : 21)	θ value	1.46607e-42 (rank : 23)
Query Neighborhood Hits	120	Target Neighborhood Hits	114	Shared Neighborhood Hits	95
SwissProt Accessions	P48443	Gene names	RXRG, NR2B3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

RXRA_MOUSE
NC score	0.947393 (rank : 22)	θ value	2.41655e-45 (rank : 18)
Query Neighborhood Hits	120	Target Neighborhood Hits	129	Shared Neighborhood Hits	95
SwissProt Accessions	P28700	Gene names	Rxra, Nr2b1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

RXRA_HUMAN
NC score	0.944823 (rank : 23)	θ value	1.41672e-45 (rank : 17)
Query Neighborhood Hits	120	Target Neighborhood Hits	223	Shared Neighborhood Hits	96
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

RXRB_MOUSE
NC score	0.943120 (rank : 24)	θ value	2.95404e-43 (rank : 21)
Query Neighborhood Hits	120	Target Neighborhood Hits	230	Shared Neighborhood Hits	99
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

HNF4G_HUMAN
NC score	0.940421 (rank : 25)	θ value	1.9192e-34 (rank : 39)
Query Neighborhood Hits	120	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q14541, Q9UH81, Q9UIS6	Gene names	HNF4G, NR2A2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

RXRB_HUMAN
NC score	0.940062 (rank : 26)	θ value	7.77379e-44 (rank : 19)
Query Neighborhood Hits	120	Target Neighborhood Hits	280	Shared Neighborhood Hits	99
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

NR1H3_HUMAN
NC score	0.939993 (rank : 27)	θ value	1.12514e-34 (rank : 38)
Query Neighborhood Hits	120	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	Q13133, Q96H87	Gene names	NR1H3, LXRA
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

NR1H3_MOUSE
NC score	0.939978 (rank : 28)	θ value	7.79185e-36 (rank : 33)
Query Neighborhood Hits	120	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Z0Y9, Q9QUH7	Gene names	Nr1h3, Lxra
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

ESR1_MOUSE
NC score	0.939833 (rank : 29)	θ value	5.96599e-36 (rank : 31)
Query Neighborhood Hits	120	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	P19785, Q9JJT5, Q9QY51, Q9QY52	Gene names	Esr1, Esr, Estr, Estra, Nr3a1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

HNF4G_MOUSE
NC score	0.939655 (rank : 30)	θ value	1.0531e-32 (rank : 45)
Query Neighborhood Hits	120	Target Neighborhood Hits	101	Shared Neighborhood Hits	94
SwissProt Accessions	Q9WUU6	Gene names	Hnf4g, Nr2a2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

COT2_HUMAN
NC score	0.939601 (rank : 31)	θ value	1.91475e-42 (rank : 24)
Query Neighborhood Hits	120	Target Neighborhood Hits	135	Shared Neighborhood Hits	97
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT2_MOUSE
NC score	0.939601 (rank : 32)	θ value	1.91475e-42 (rank : 25)
Query Neighborhood Hits	120	Target Neighborhood Hits	135	Shared Neighborhood Hits	97
SwissProt Accessions	P43135	Gene names	Nr2f2, Aporp1, Arp-1, Arp1, Tfcoup2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

ESR1_HUMAN
NC score	0.939069 (rank : 33)	θ value	7.79185e-36 (rank : 32)
Query Neighborhood Hits	120	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P03372, Q13511, Q14276, Q9NU51, Q9UDZ7, Q9UIS7	Gene names	ESR1, ESR, NR3A1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

COT1_MOUSE
NC score	0.938994 (rank : 34)	θ value	5.57106e-42 (rank : 28)
Query Neighborhood Hits	120	Target Neighborhood Hits	160	Shared Neighborhood Hits	98
SwissProt Accessions	Q60632, Q61438	Gene names	Nr2f1, Erbal3, Tfcoup1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I).

COT1_HUMAN
NC score	0.938875 (rank : 35)	θ value	5.57106e-42 (rank : 27)
Query Neighborhood Hits	120	Target Neighborhood Hits	159	Shared Neighborhood Hits	99
SwissProt Accessions	P10589	Gene names	NR2F1, EAR3, ERBAL3, TFCOUP1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I) (V-ERBA-related protein EAR-3).

EAR2_MOUSE
NC score	0.938807 (rank : 36)	θ value	9.20422e-37 (rank : 30)
Query Neighborhood Hits	120	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	P43136, Q61504	Gene names	Nr2f6, Ear-2, Ear2, Erbal2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

EAR2_HUMAN
NC score	0.938337 (rank : 37)	θ value	1.01765e-35 (rank : 34)
Query Neighborhood Hits	120	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P10588, Q9BUE8	Gene names	NR2F6, EAR2, ERBAL2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

HNF4A_HUMAN
NC score	0.938114 (rank : 38)	θ value	2.12192e-33 (rank : 43)
Query Neighborhood Hits	120	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P41235, O00659, O00723, Q14540, Q92653, Q92654, Q92655, Q99864, Q9NQH0	Gene names	HNF4A, HNF4, NR2A1, TCF14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

ESR2_HUMAN
NC score	0.937903 (rank : 39)	θ value	3.61944e-33 (rank : 44)
Query Neighborhood Hits	120	Target Neighborhood Hits	110	Shared Neighborhood Hits	94
SwissProt Accessions	Q92731, O60608, O60685, O60702, O60703, O75583, O75584, Q86Z31, Q9UEV6, Q9UHD3, Q9UQK9	Gene names	ESR2, ESTRB, NR3A2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

HNF4A_MOUSE
NC score	0.937524 (rank : 40)	θ value	4.42448e-31 (rank : 47)
Query Neighborhood Hits	120	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P49698	Gene names	Hnf4a, Hnf-4, Hnf4, Nr2a1, Tcf14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

ESR2_MOUSE
NC score	0.936926 (rank : 41)	θ value	1.37539e-32 (rank : 46)
Query Neighborhood Hits	120	Target Neighborhood Hits	110	Shared Neighborhood Hits	94
SwissProt Accessions	O08537, O35635, O70519	Gene names	Esr2, Estrb, Nr3a2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

THA_MOUSE
NC score	0.934670 (rank : 42)	θ value	1.32909e-35 (rank : 35)
Query Neighborhood Hits	120	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P63058, P10685, P15827, P16416, P37241, Q63107, Q63195, Q63196, Q99146	Gene names	Thra, C-erba-alpha, Nr1a1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1).

THA_HUMAN
NC score	0.934551 (rank : 43)	θ value	1.73584e-35 (rank : 36)
Query Neighborhood Hits	120	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P10827, P21205, Q8N6A1, Q96H73	Gene names	THRA, ERBA1, NR1A1, THRA1
Domain Architecture
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1) (EAR-7) (EAR7).

NR1I3_MOUSE
NC score	0.933990 (rank : 44)	θ value	1.73987e-27 (rank : 53)
Query Neighborhood Hits	120	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	O35627, O35628	Gene names	Nr1i3, Car
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67).

NR2E1_MOUSE
NC score	0.933375 (rank : 45)	θ value	9.2256e-29 (rank : 48)
Query Neighborhood Hits	120	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	Q64104	Gene names	Nr2e1, Tll, Tlx
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (mTll).

NR2E3_MOUSE
NC score	0.933182 (rank : 46)	θ value	4.57862e-28 (rank : 50)
Query Neighborhood Hits	120	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QXZ7	Gene names	Nr2e3, Pnr, Rnr
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

NR1H4_HUMAN
NC score	0.933047 (rank : 47)	θ value	2.27234e-27 (rank : 54)
Query Neighborhood Hits	120	Target Neighborhood Hits	112	Shared Neighborhood Hits	94
SwissProt Accessions	Q96RI1, Q8NFP5, Q8NFP6, Q92943	Gene names	NR1H4, BAR, FXR, HRR1, RIP14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

NR1H4_MOUSE
NC score	0.932547 (rank : 48)	θ value	3.87602e-27 (rank : 55)
Query Neighborhood Hits	120	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	Q60641, Q60642, Q60643	Gene names	Nr1h4, Bar, Fxr, Rip14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

NR2E3_HUMAN
NC score	0.932401 (rank : 49)	θ value	3.50572e-28 (rank : 49)
Query Neighborhood Hits	120	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y5X4, Q9UHM4	Gene names	NR2E3, PNR, RNR
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

NR2E1_HUMAN
NC score	0.932003 (rank : 50)	θ value	5.97985e-28 (rank : 51)
Query Neighborhood Hits	120	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y466	Gene names	NR2E1, TLX
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (hTll).

NR1I3_HUMAN
NC score	0.929428 (rank : 51)	θ value	1.09232e-21 (rank : 82)
Query Neighborhood Hits	120	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	Q14994	Gene names	NR1I3, CAR
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Constitutive activator of retinoid response) (Constitutive active response) (Orphan nuclear receptor MB67).

THB2_HUMAN
NC score	0.928448 (rank : 52)	θ value	3.27365e-34 (rank : 41)
Query Neighborhood Hits	120	Target Neighborhood Hits	104	Shared Neighborhood Hits	94
SwissProt Accessions	P37243	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor beta-2.

THB1_HUMAN
NC score	0.928326 (rank : 53)	θ value	8.61488e-35 (rank : 37)
Query Neighborhood Hits	120	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P10828, Q13986	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture
Description	Thyroid hormone receptor beta-1.

NR1H2_MOUSE
NC score	0.928268 (rank : 54)	θ value	8.63488e-27 (rank : 56)
Query Neighborhood Hits	120	Target Neighborhood Hits	109	Shared Neighborhood Hits	95
SwissProt Accessions	Q60644	Gene names	Nr1h2, Lxrb, Rip15, Unr, Unr2
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Retinoid X receptor-interacting protein No.15).

THB2_MOUSE
NC score	0.927567 (rank : 55)	θ value	1.9192e-34 (rank : 40)
Query Neighborhood Hits	120	Target Neighborhood Hits	106	Shared Neighborhood Hits	94
SwissProt Accessions	P37244	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-2.

THB1_MOUSE
NC score	0.927446 (rank : 56)	θ value	5.584e-34 (rank : 42)
Query Neighborhood Hits	120	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P37242	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-1.

STF1_HUMAN
NC score	0.922009 (rank : 57)	θ value	1.05554e-24 (rank : 66)
Query Neighborhood Hits	120	Target Neighborhood Hits	132	Shared Neighborhood Hits	95
SwissProt Accessions	Q13285, O15196	Gene names	NR5A1, AD4BP, FTZF1, SF1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1).

NR6A1_HUMAN
NC score	0.921947 (rank : 58)	θ value	2.43343e-21 (rank : 84)
Query Neighborhood Hits	120	Target Neighborhood Hits	108	Shared Neighborhood Hits	94
SwissProt Accessions	Q15406, O00551, O00603, Q8NHQ0, Q92898, Q99802	Gene names	NR6A1, GCNF
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

NR6A1_MOUSE
NC score	0.921563 (rank : 59)	θ value	2.43343e-21 (rank : 85)
Query Neighborhood Hits	120	Target Neighborhood Hits	110	Shared Neighborhood Hits	94
SwissProt Accessions	Q64249	Gene names	Nr6a1, Gcnf
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

STF1_MOUSE
NC score	0.921195 (rank : 60)	θ value	1.05554e-24 (rank : 67)
Query Neighborhood Hits	120	Target Neighborhood Hits	137	Shared Neighborhood Hits	94
SwissProt Accessions	P33242	Gene names	Nr5a1, Ftzf1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1) (Embryonal LTR-binding protein) (ELP) (Embryonal long terminal repeat- binding protein) (Steroid hydroxylase positive regulator).

NR1D1_HUMAN
NC score	0.920260 (rank : 61)	θ value	2.87452e-22 (rank : 74)
Query Neighborhood Hits	120	Target Neighborhood Hits	140	Shared Neighborhood Hits	95
SwissProt Accessions	P20393, Q15304	Gene names	NR1D1, EAR1, HREV, THRAL
Domain Architecture
Description	Orphan nuclear receptor NR1D1 (V-erbA-related protein EAR-1) (Rev- erbA-alpha).

PPARD_HUMAN
NC score	0.919549 (rank : 62)	θ value	8.63488e-27 (rank : 57)
Query Neighborhood Hits	120	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q03181, Q7Z5K0, Q9BUD4	Gene names	PPARD, NR1C2, PPARB
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1) (NUCI).

PPARA_MOUSE
NC score	0.919341 (rank : 63)	θ value	1.24688e-25 (rank : 62)
Query Neighborhood Hits	120	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	P23204	Gene names	Ppara, Nr1c1, Ppar
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

TR2_HUMAN
NC score	0.919087 (rank : 64)	θ value	1.16704e-23 (rank : 69)
Query Neighborhood Hits	120	Target Neighborhood Hits	110	Shared Neighborhood Hits	94
SwissProt Accessions	P13056	Gene names	NR2C1, TR2
Domain Architecture
Description	Orphan nuclear receptor TR2 (Testicular receptor 2).

PPARD_MOUSE
NC score	0.918761 (rank : 65)	θ value	2.51237e-26 (rank : 58)
Query Neighborhood Hits	120	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P35396, P37239	Gene names	Ppard, Nr1c2, Pparb
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1).

PPARA_HUMAN
NC score	0.918517 (rank : 66)	θ value	2.77775e-25 (rank : 64)
Query Neighborhood Hits	120	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q07869, Q16241, Q92486, Q92689, Q9Y3N1	Gene names	PPARA, NR1C1, PPAR
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

PPARG_HUMAN
NC score	0.917675 (rank : 67)	θ value	3.28125e-26 (rank : 59)
Query Neighborhood Hits	120	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37231, O00684, O00710, O14515, Q15178, Q15179, Q15180, Q15832, Q86U60, Q96J12	Gene names	PPARG, NR1C3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

PPARG_MOUSE
NC score	0.917538 (rank : 68)	θ value	5.59698e-26 (rank : 60)
Query Neighborhood Hits	120	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37238	Gene names	Pparg, Nr1c3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

VDR_MOUSE
NC score	0.916105 (rank : 69)	θ value	6.18819e-25 (rank : 65)
Query Neighborhood Hits	120	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P48281	Gene names	Vdr, Nr1i1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

NR5A2_HUMAN
NC score	0.915217 (rank : 70)	θ value	1.33217e-27 (rank : 52)
Query Neighborhood Hits	120	Target Neighborhood Hits	112	Shared Neighborhood Hits	94
SwissProt Accessions	O00482, O95642	Gene names	NR5A2, B1F, CPF, FTF
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Alpha-1-fetoprotein transcription factor) (Hepatocytic transcription factor) (B1-binding factor) (hB1F) (CYP7A promoter-binding factor) (Liver receptor homolog 1) (LRH-1).

PXR_HUMAN
NC score	0.915062 (rank : 71)	θ value	4.9032e-22 (rank : 77)
Query Neighborhood Hits	120	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	O75469, Q96AC7, Q9UJ22, Q9UJ23, Q9UJ24, Q9UJ25, Q9UJ26, Q9UJ27	Gene names	NR1I2, PXR
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor) (Orphan nuclear receptor PAR1) (Steroid and xenobiotic receptor) (SXR).

NR5A2_MOUSE
NC score	0.915002 (rank : 72)	θ value	7.30988e-26 (rank : 61)
Query Neighborhood Hits	120	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	P45448	Gene names	Nr5a2, Lrh1
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Liver receptor homolog 1) (LRH-1).

NR1D2_HUMAN
NC score	0.914608 (rank : 73)	θ value	1.29031e-22 (rank : 73)
Query Neighborhood Hits	120	Target Neighborhood Hits	115	Shared Neighborhood Hits	94
SwissProt Accessions	Q14995, O00402, Q86XD4	Gene names	NR1D2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (EAR-1R) (Orphan nuclear hormone receptor BD73).

NR1H2_HUMAN
NC score	0.914202 (rank : 74)	θ value	1.38178e-16 (rank : 94)
Query Neighborhood Hits	120	Target Neighborhood Hits	114	Shared Neighborhood Hits	94
SwissProt Accessions	P55055, Q12970	Gene names	NR1H2, LXRB, NER, UNR
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Nuclear receptor NER).

PXR_MOUSE
NC score	0.912837 (rank : 75)	θ value	1.33526e-19 (rank : 90)
Query Neighborhood Hits	120	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	O54915	Gene names	Nr1i2, Pxr
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor).

NR1D2_MOUSE
NC score	0.912204 (rank : 76)	θ value	5.79196e-23 (rank : 71)
Query Neighborhood Hits	120	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	Q60674, Q60646	Gene names	Nr1d2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (Orphan nuclear receptor RVR).

VDR_HUMAN
NC score	0.912044 (rank : 77)	θ value	4.29542e-18 (rank : 93)
Query Neighborhood Hits	120	Target Neighborhood Hits	112	Shared Neighborhood Hits	94
SwissProt Accessions	P11473	Gene names	VDR, NR1I1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

TR2_MOUSE
NC score	0.904153 (rank : 78)	θ value	3.39556e-23 (rank : 70)
Query Neighborhood Hits	120	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q505F1, P97763, Q3UIJ7, Q4U1Z4, Q60927, Q62152, Q8VIJ3	Gene names	Nr2c1, Tr2, Tr2-11
Domain Architecture	No domain graphic available
Description	Orphan nuclear receptor TR2 (Testicular receptor 2) (mTR2).

RORG_MOUSE
NC score	0.903048 (rank : 79)	θ value	4.9032e-22 (rank : 79)
Query Neighborhood Hits	120	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	P51450, Q61027, Q91YT5, Q9QXD9, Q9R177	Gene names	Rorc, Nr1f3, Rorg, Thor
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma) (Thymus orphan receptor) (TOR).

RORA_HUMAN
NC score	0.900750 (rank : 80)	θ value	2.87452e-22 (rank : 75)
Query Neighborhood Hits	120	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P35398, P35397, P35399, P45445, Q96H83	Gene names	RORA, NR1F1, RZRA
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

RORB_MOUSE
NC score	0.900549 (rank : 81)	θ value	8.36355e-22 (rank : 81)
Query Neighborhood Hits	120	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	Q8R1B8	Gene names	Rorb, Nr1f2
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORB_HUMAN
NC score	0.900298 (rank : 82)	θ value	8.36355e-22 (rank : 80)
Query Neighborhood Hits	120	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	Q92753, Q8WX73	Gene names	RORB, NR1F2, RZRB
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORA_MOUSE
NC score	0.899985 (rank : 83)	θ value	2.87452e-22 (rank : 76)
Query Neighborhood Hits	120	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P51448, P70283, P97741, P97773, Q923G1	Gene names	Rora, Nr1f1, Rzra
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

RORG_HUMAN
NC score	0.898982 (rank : 84)	θ value	4.9032e-22 (rank : 78)
Query Neighborhood Hits	120	Target Neighborhood Hits	119	Shared Neighborhood Hits	94
SwissProt Accessions	P51449, Q8N5V7, Q8NCY8	Gene names	RORC, NR1F3, RORG, RZRG
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma).

TR4_HUMAN
NC score	0.898680 (rank : 85)	θ value	1.09232e-21 (rank : 83)
Query Neighborhood Hits	120	Target Neighborhood Hits	117	Shared Neighborhood Hits	94
SwissProt Accessions	P49116, P55092	Gene names	NR2C2, TAK1, TR4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

TR4_MOUSE
NC score	0.897749 (rank : 86)	θ value	4.15078e-21 (rank : 87)
Query Neighborhood Hits	120	Target Neighborhood Hits	115	Shared Neighborhood Hits	94
SwissProt Accessions	P49117, P55093	Gene names	Nr2c2, Mtr2r1, Tak1, Tr4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

GCR_HUMAN
NC score	0.886442 (rank : 87)	θ value	2.12685e-25 (rank : 63)
Query Neighborhood Hits	120	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P04150, P04151, Q53EP5, Q6N0A4	Gene names	NR3C1, GRL
Domain Architecture
Description	Glucocorticoid receptor (GR).

GCR_MOUSE
NC score	0.881793 (rank : 88)	θ value	5.23862e-24 (rank : 68)
Query Neighborhood Hits	120	Target Neighborhood Hits	117	Shared Neighborhood Hits	95
SwissProt Accessions	P06537, Q61628, Q61629	Gene names	Nr3c1, Grl, Grl1
Domain Architecture
Description	Glucocorticoid receptor (GR).

ANDR_MOUSE
NC score	0.879756 (rank : 89)	θ value	4.15078e-21 (rank : 86)
Query Neighborhood Hits	120	Target Neighborhood Hits	133	Shared Neighborhood Hits	96
SwissProt Accessions	P19091	Gene names	Ar, Nr3c4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

MCR_HUMAN
NC score	0.878890 (rank : 90)	θ value	9.87957e-23 (rank : 72)
Query Neighborhood Hits	120	Target Neighborhood Hits	149	Shared Neighborhood Hits	96
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

ANDR_HUMAN
NC score	0.876745 (rank : 91)	θ value	1.13037e-18 (rank : 92)
Query Neighborhood Hits	120	Target Neighborhood Hits	126	Shared Neighborhood Hits	96
SwissProt Accessions	P10275	Gene names	AR, DHTR, NR3C4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

MCR_MOUSE
NC score	0.875010 (rank : 92)	θ value	9.24701e-21 (rank : 88)
Query Neighborhood Hits	120	Target Neighborhood Hits	162	Shared Neighborhood Hits	96
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

PRGR_HUMAN
NC score	0.870641 (rank : 93)	θ value	8.65492e-19 (rank : 91)
Query Neighborhood Hits	120	Target Neighborhood Hits	163	Shared Neighborhood Hits	96
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

PRGR_MOUSE
NC score	0.865815 (rank : 94)	θ value	2.69047e-20 (rank : 89)
Query Neighborhood Hits	120	Target Neighborhood Hits	286	Shared Neighborhood Hits	95
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

SHP_HUMAN
NC score	0.443577 (rank : 95)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	120	Target Neighborhood Hits	57	Shared Neighborhood Hits	52
SwissProt Accessions	Q15466, Q5QP36	Gene names	NR0B2, SHP
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

DAX1_MOUSE
NC score	0.435795 (rank : 96)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	120	Target Neighborhood Hits	70	Shared Neighborhood Hits	56
SwissProt Accessions	Q61066, O09068, O09147	Gene names	Nr0b1, Ahch, Dax1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1).

SHP_MOUSE
NC score	0.433624 (rank : 97)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	120	Target Neighborhood Hits	53	Shared Neighborhood Hits	49
SwissProt Accessions	Q62227, Q53Z53	Gene names	Nr0b2, Shp
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

DAX1_HUMAN
NC score	0.404753 (rank : 98)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	120	Target Neighborhood Hits	65	Shared Neighborhood Hits	55
SwissProt Accessions	P51843, Q96F69	Gene names	NR0B1, AHC, DAX1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1) (DSS-AHC critical region on the X chromosome protein 1).

DAP1_HUMAN
NC score	0.037391 (rank : 99)	θ value	0.47712 (rank : 97)
Query Neighborhood Hits	120	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	P51397, Q9BUC9	Gene names	DAP, DAP1
Domain Architecture	No domain graphic available
Description	Death-associated protein 1 (DAP-1).

CO4A5_HUMAN
NC score	0.017450 (rank : 100)	θ value	0.279714 (rank : 96)
Query Neighborhood Hits	120	Target Neighborhood Hits	383	Shared Neighborhood Hits	15
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

CA043_HUMAN
NC score	0.014567 (rank : 101)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	120	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BWL3, Q5M801, Q5VU73, Q5VU83, Q96HP7, Q9UFU2, Q9UGL7, Q9UGL8, Q9Y2R6	Gene names	C1orf43, NICE3, NS5ATP4
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf43 (Hepatitis C virus NS5A-transactivated protein 4) (Protein NICE-3) (S863-3).

CO5A3_HUMAN
NC score	0.013042 (rank : 102)	θ value	0.21417 (rank : 95)
Query Neighborhood Hits	120	Target Neighborhood Hits	433	Shared Neighborhood Hits	13
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

NCOA6_MOUSE
NC score	0.012998 (rank : 103)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	120	Target Neighborhood Hits	1076	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NCOA6_HUMAN
NC score	0.011638 (rank : 104)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	120	Target Neighborhood Hits	1202	Shared Neighborhood Hits	25
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

CO4A4_HUMAN
NC score	0.011160 (rank : 105)	θ value	1.81305 (rank : 102)
Query Neighborhood Hits	120	Target Neighborhood Hits	440	Shared Neighborhood Hits	14
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

DACH1_MOUSE
NC score	0.011139 (rank : 106)	θ value	1.38821 (rank : 100)
Query Neighborhood Hits	120	Target Neighborhood Hits	228	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QYB2, O88716, Q8BPQ0, Q8C8D7, Q9QY47, Q9R218, Q9Z0Y5	Gene names	Dach1, Dach
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

MAML1_HUMAN
NC score	0.010677 (rank : 107)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	120	Target Neighborhood Hits	228	Shared Neighborhood Hits	9
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

CO4A2_MOUSE
NC score	0.010483 (rank : 108)	θ value	1.06291 (rank : 98)
Query Neighborhood Hits	120	Target Neighborhood Hits	492	Shared Neighborhood Hits	16
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

COJA1_HUMAN
NC score	0.009897 (rank : 109)	θ value	1.81305 (rank : 103)
Query Neighborhood Hits	120	Target Neighborhood Hits	323	Shared Neighborhood Hits	10
SwissProt Accessions	Q14993, Q00559, Q05850, Q12885, Q13676, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2	Gene names	COL19A1
Domain Architecture
Description	Collagen alpha-1(XIX) chain precursor (Collagen alpha-1(Y) chain).

HGS_HUMAN
NC score	0.008494 (rank : 110)	θ value	1.81305 (rank : 104)
Query Neighborhood Hits	120	Target Neighborhood Hits	517	Shared Neighborhood Hits	8
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HGS_MOUSE
NC score	0.007910 (rank : 111)	θ value	2.36792 (rank : 105)
Query Neighborhood Hits	120	Target Neighborhood Hits	589	Shared Neighborhood Hits	9
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

R3HD2_MOUSE
NC score	0.007803 (rank : 112)	θ value	4.03905 (rank : 110)
Query Neighborhood Hits	120	Target Neighborhood Hits	397	Shared Neighborhood Hits	10
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

MAML1_MOUSE
NC score	0.007538 (rank : 113)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	120	Target Neighborhood Hits	279	Shared Neighborhood Hits	12
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

CMTA1_HUMAN
NC score	0.007087 (rank : 114)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	120	Target Neighborhood Hits	217	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

4ET_HUMAN
NC score	0.006950 (rank : 115)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	120	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRA8, Q8NCF2, Q9H708	Gene names	EIF4ENIF1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

CBP_HUMAN
NC score	0.004980 (rank : 116)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	120	Target Neighborhood Hits	941	Shared Neighborhood Hits	14
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

IF4G1_HUMAN
NC score	0.004638 (rank : 117)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	120	Target Neighborhood Hits	347	Shared Neighborhood Hits	6
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

A2MG_HUMAN
NC score	0.004603 (rank : 118)	θ value	1.81305 (rank : 101)
Query Neighborhood Hits	120	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	P01023, Q13677, Q59F47, Q5QTS0, Q68DN2, Q6PIY3, Q6PN97	Gene names	A2M
Domain Architecture
Description	Alpha-2-macroglobulin precursor (Alpha-2-M).

GRLF1_HUMAN
NC score	0.003187 (rank : 119)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	120	Target Neighborhood Hits	167	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

SMBT1_HUMAN
NC score	0.002699 (rank : 120)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	120	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UHJ3, Q96C73, Q9Y4Q9	Gene names	SFMBT1, RU1
Domain Architecture	No domain graphic available
Description	Scm-like with four MBT domains protein 1 (Renal ubiquitous protein 1).

ADAM8_HUMAN
NC score	0.001712 (rank : 121)	θ value	1.38821 (rank : 99)
Query Neighborhood Hits	120	Target Neighborhood Hits	327	Shared Neighborhood Hits	4
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

SSH1_HUMAN
NC score	0.001249 (rank : 122)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	120	Target Neighborhood Hits	164	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).

TENX_HUMAN
NC score	-0.003543 (rank : 123)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	120	Target Neighborhood Hits	789	Shared Neighborhood Hits	8
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

GLI2_HUMAN
NC score	-0.006168 (rank : 124)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	120	Target Neighborhood Hits	971	Shared Neighborhood Hits	12
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).