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Network neighborhood for query Sequence : COT2_HUMAN

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COT2_HUMAN
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

COT1_HUMAN
θ value	0 (rank : 1)	NC score	0.998028 (rank : 4)
Query Neighborhood Hits	135	Target Neighborhood Hits	159	Shared Neighborhood Hits	116
SwissProt Accessions	P10589	Gene names	NR2F1, EAR3, ERBAL3, TFCOUP1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I) (V-ERBA-related protein EAR-3).

COT1_MOUSE
θ value	0 (rank : 2)	NC score	0.998128 (rank : 3)
Query Neighborhood Hits	135	Target Neighborhood Hits	160	Shared Neighborhood Hits	114
SwissProt Accessions	Q60632, Q61438	Gene names	Nr2f1, Erbal3, Tfcoup1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I).

COT2_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	135	Target Neighborhood Hits	135	Shared Neighborhood Hits	135
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT2_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 2)
Query Neighborhood Hits	135	Target Neighborhood Hits	135	Shared Neighborhood Hits	135
SwissProt Accessions	P43135	Gene names	Nr2f2, Aporp1, Arp-1, Arp1, Tfcoup2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

EAR2_HUMAN
θ value	1.28961e-139 (rank : 5)	NC score	0.996795 (rank : 5)
Query Neighborhood Hits	135	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P10588, Q9BUE8	Gene names	NR2F6, EAR2, ERBAL2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

EAR2_MOUSE
θ value	1.74296e-136 (rank : 6)	NC score	0.996728 (rank : 6)
Query Neighborhood Hits	135	Target Neighborhood Hits	104	Shared Neighborhood Hits	98
SwissProt Accessions	P43136, Q61504	Gene names	Nr2f6, Ear-2, Ear2, Erbal2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

RXRA_MOUSE
θ value	2.47765e-74 (rank : 7)	NC score	0.980144 (rank : 13)
Query Neighborhood Hits	135	Target Neighborhood Hits	129	Shared Neighborhood Hits	98
SwissProt Accessions	P28700	Gene names	Rxra, Nr2b1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

RXRA_HUMAN
θ value	3.23591e-74 (rank : 8)	NC score	0.977225 (rank : 14)
Query Neighborhood Hits	135	Target Neighborhood Hits	223	Shared Neighborhood Hits	101
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

RXRG_HUMAN
θ value	9.41505e-74 (rank : 9)	NC score	0.980861 (rank : 11)
Query Neighborhood Hits	135	Target Neighborhood Hits	114	Shared Neighborhood Hits	100
SwissProt Accessions	P48443	Gene names	RXRG, NR2B3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

RXRG_MOUSE
θ value	6.10265e-73 (rank : 10)	NC score	0.980648 (rank : 12)
Query Neighborhood Hits	135	Target Neighborhood Hits	113	Shared Neighborhood Hits	98
SwissProt Accessions	P28705	Gene names	Rxrg, Nr2b3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

NR2E3_HUMAN
θ value	4.37348e-71 (rank : 11)	NC score	0.985767 (rank : 7)
Query Neighborhood Hits	135	Target Neighborhood Hits	102	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y5X4, Q9UHM4	Gene names	NR2E3, PNR, RNR
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

NR2E3_MOUSE
θ value	8.24801e-70 (rank : 12)	NC score	0.985053 (rank : 8)
Query Neighborhood Hits	135	Target Neighborhood Hits	113	Shared Neighborhood Hits	98
SwissProt Accessions	Q9QXZ7	Gene names	Nr2e3, Pnr, Rnr
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

RXRB_HUMAN
θ value	3.13423e-69 (rank : 13)	NC score	0.971892 (rank : 20)
Query Neighborhood Hits	135	Target Neighborhood Hits	280	Shared Neighborhood Hits	107
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

RXRB_MOUSE
θ value	6.98233e-69 (rank : 14)	NC score	0.975931 (rank : 19)
Query Neighborhood Hits	135	Target Neighborhood Hits	230	Shared Neighborhood Hits	102
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

NR2E1_HUMAN
θ value	1.71981e-67 (rank : 15)	NC score	0.983911 (rank : 9)
Query Neighborhood Hits	135	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y466	Gene names	NR2E1, TLX
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (hTll).

NR2E1_MOUSE
θ value	1.71981e-67 (rank : 16)	NC score	0.983828 (rank : 10)
Query Neighborhood Hits	135	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	Q64104	Gene names	Nr2e1, Tll, Tlx
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (mTll).

HNF4A_MOUSE
θ value	1.7238e-59 (rank : 17)	NC score	0.976463 (rank : 16)
Query Neighborhood Hits	135	Target Neighborhood Hits	103	Shared Neighborhood Hits	99
SwissProt Accessions	P49698	Gene names	Hnf4a, Hnf-4, Hnf4, Nr2a1, Tcf14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

HNF4A_HUMAN
θ value	3.25095e-58 (rank : 18)	NC score	0.975961 (rank : 18)
Query Neighborhood Hits	135	Target Neighborhood Hits	105	Shared Neighborhood Hits	99
SwissProt Accessions	P41235, O00659, O00723, Q14540, Q92653, Q92654, Q92655, Q99864, Q9NQH0	Gene names	HNF4A, HNF4, NR2A1, TCF14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

HNF4G_MOUSE
θ value	2.10721e-57 (rank : 19)	NC score	0.976328 (rank : 17)
Query Neighborhood Hits	135	Target Neighborhood Hits	101	Shared Neighborhood Hits	98
SwissProt Accessions	Q9WUU6	Gene names	Hnf4g, Nr2a2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

HNF4G_HUMAN
θ value	3.59435e-57 (rank : 20)	NC score	0.976621 (rank : 15)
Query Neighborhood Hits	135	Target Neighborhood Hits	100	Shared Neighborhood Hits	98
SwissProt Accessions	Q14541, Q9UH81, Q9UIS6	Gene names	HNF4G, NR2A2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

ERR2_HUMAN
θ value	9.48078e-50 (rank : 21)	NC score	0.954597 (rank : 24)
Query Neighborhood Hits	135	Target Neighborhood Hits	108	Shared Neighborhood Hits	98
SwissProt Accessions	O95718, Q9HCB4	Gene names	ESRRB, ERRB2, NR3B2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2) (ERR beta-2).

ERR2_MOUSE
θ value	9.48078e-50 (rank : 22)	NC score	0.957033 (rank : 21)
Query Neighborhood Hits	135	Target Neighborhood Hits	109	Shared Neighborhood Hits	98
SwissProt Accessions	Q61539, O09067, O09146	Gene names	Esrrb, Err-2, Err2, Nr3b2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2).

ERR3_HUMAN
θ value	1.36902e-48 (rank : 23)	NC score	0.956791 (rank : 22)
Query Neighborhood Hits	135	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P62508, O75454, O96021, Q68DA0, Q6P274, Q6PK28, Q6TS38, Q9R1F3, Q9UNJ4	Gene names	ESRRG, ERR3, ERRG2, KIAA0832, NR3B3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (ERR gamma-2).

ERR3_MOUSE
θ value	1.36902e-48 (rank : 24)	NC score	0.956791 (rank : 23)
Query Neighborhood Hits	135	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P62509, O75454, O96021, Q8CHC9, Q9R1F3	Gene names	Esrrg, Err3, Kiaa0832, Nr3b3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3).

ERR1_HUMAN
θ value	1.73182e-43 (rank : 25)	NC score	0.953815 (rank : 25)
Query Neighborhood Hits	135	Target Neighborhood Hits	157	Shared Neighborhood Hits	102
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

NR4A2_HUMAN
θ value	1.91475e-42 (rank : 26)	NC score	0.939601 (rank : 28)
Query Neighborhood Hits	135	Target Neighborhood Hits	120	Shared Neighborhood Hits	97
SwissProt Accessions	P43354, Q16311	Gene names	NR4A2, NOT, NURR1, TINUR
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (Immediate-early response protein NOT) (Transcriptionally-inducible nuclear receptor).

NR4A2_MOUSE
θ value	1.91475e-42 (rank : 27)	NC score	0.939643 (rank : 26)
Query Neighborhood Hits	135	Target Neighborhood Hits	121	Shared Neighborhood Hits	97
SwissProt Accessions	Q06219, O08690	Gene names	Nr4a2, Nurr1
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (NUR- related factor 1).

NR4A1_HUMAN
θ value	1.3722e-40 (rank : 28)	NC score	0.939611 (rank : 27)
Query Neighborhood Hits	135	Target Neighborhood Hits	133	Shared Neighborhood Hits	96
SwissProt Accessions	P22736	Gene names	NR4A1, GFRP1, HMR, NAK1
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Early response protein NAK1) (TR3 orphan receptor) (ST-59).

NR4A1_MOUSE
θ value	8.89434e-40 (rank : 29)	NC score	0.938328 (rank : 29)
Query Neighborhood Hits	135	Target Neighborhood Hits	128	Shared Neighborhood Hits	94
SwissProt Accessions	P12813	Gene names	Nr4a1, Gfrp, Hmr, N10, Nur77
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Nuclear hormone receptor NUR/77) (N10 nuclear protein).

RARG1_HUMAN
θ value	8.89434e-40 (rank : 30)	NC score	0.934059 (rank : 37)
Query Neighborhood Hits	135	Target Neighborhood Hits	107	Shared Neighborhood Hits	95
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARG2_HUMAN
θ value	8.89434e-40 (rank : 31)	NC score	0.934209 (rank : 35)
Query Neighborhood Hits	135	Target Neighborhood Hits	109	Shared Neighborhood Hits	95
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

RARG1_MOUSE
θ value	7.52953e-39 (rank : 32)	NC score	0.933473 (rank : 42)
Query Neighborhood Hits	135	Target Neighborhood Hits	113	Shared Neighborhood Hits	96
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

RARG2_MOUSE
θ value	7.52953e-39 (rank : 33)	NC score	0.933771 (rank : 38)
Query Neighborhood Hits	135	Target Neighborhood Hits	114	Shared Neighborhood Hits	96
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

RARB_HUMAN
θ value	9.83387e-39 (rank : 34)	NC score	0.933748 (rank : 39)
Query Neighborhood Hits	135	Target Neighborhood Hits	118	Shared Neighborhood Hits	94
SwissProt Accessions	P10826, P12891, Q00989, Q15298, Q9UN48	Gene names	RARB, HAP, NR1B2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta) (RAR-epsilon) (HBV-activated protein).

RARB_MOUSE
θ value	3.73686e-38 (rank : 35)	NC score	0.933685 (rank : 40)
Query Neighborhood Hits	135	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	P22605, P11417, P22604	Gene names	Rarb, Nr1b2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta).

RARA_HUMAN
θ value	4.88048e-38 (rank : 36)	NC score	0.934284 (rank : 34)
Query Neighborhood Hits	135	Target Neighborhood Hits	118	Shared Neighborhood Hits	96
SwissProt Accessions	P10276, P78456, Q13440, Q13441, Q9NQS0	Gene names	RARA, NR1B1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARA_MOUSE
θ value	1.08726e-37 (rank : 37)	NC score	0.934181 (rank : 36)
Query Neighborhood Hits	135	Target Neighborhood Hits	113	Shared Neighborhood Hits	96
SwissProt Accessions	P11416, P22603	Gene names	Rara, Nr1b1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

NR4A3_MOUSE
θ value	1.32909e-35 (rank : 38)	NC score	0.937225 (rank : 30)
Query Neighborhood Hits	135	Target Neighborhood Hits	127	Shared Neighborhood Hits	96
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

TR4_HUMAN
θ value	5.0505e-35 (rank : 39)	NC score	0.934718 (rank : 32)
Query Neighborhood Hits	135	Target Neighborhood Hits	117	Shared Neighborhood Hits	98
SwissProt Accessions	P49116, P55092	Gene names	NR2C2, TAK1, TR4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

TR4_MOUSE
θ value	6.59618e-35 (rank : 40)	NC score	0.934374 (rank : 33)
Query Neighborhood Hits	135	Target Neighborhood Hits	115	Shared Neighborhood Hits	98
SwissProt Accessions	P49117, P55093	Gene names	Nr2c2, Mtr2r1, Tak1, Tr4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

NR4A3_HUMAN
θ value	3.27365e-34 (rank : 41)	NC score	0.935939 (rank : 31)
Query Neighborhood Hits	135	Target Neighborhood Hits	131	Shared Neighborhood Hits	98
SwissProt Accessions	Q92570, Q12935, Q14979, Q16420, Q4VXA9, Q9UEK2, Q9UEK3	Gene names	NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1) (Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphan receptor).

ESR1_MOUSE
θ value	3.06405e-32 (rank : 42)	NC score	0.929770 (rank : 45)
Query Neighborhood Hits	135	Target Neighborhood Hits	104	Shared Neighborhood Hits	95
SwissProt Accessions	P19785, Q9JJT5, Q9QY51, Q9QY52	Gene names	Esr1, Esr, Estr, Estra, Nr3a1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

NR1H3_MOUSE
θ value	3.06405e-32 (rank : 43)	NC score	0.924452 (rank : 51)
Query Neighborhood Hits	135	Target Neighborhood Hits	102	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z0Y9, Q9QUH7	Gene names	Nr1h3, Lxra
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

ESR1_HUMAN
θ value	4.00176e-32 (rank : 44)	NC score	0.929653 (rank : 46)
Query Neighborhood Hits	135	Target Neighborhood Hits	105	Shared Neighborhood Hits	95
SwissProt Accessions	P03372, Q13511, Q14276, Q9NU51, Q9UDZ7, Q9UIS7	Gene names	ESR1, ESR, NR3A1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

NR1H3_HUMAN
θ value	4.00176e-32 (rank : 45)	NC score	0.925613 (rank : 50)
Query Neighborhood Hits	135	Target Neighborhood Hits	104	Shared Neighborhood Hits	95
SwissProt Accessions	Q13133, Q96H87	Gene names	NR1H3, LXRA
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

PPARD_MOUSE
θ value	1.52067e-31 (rank : 46)	NC score	0.914913 (rank : 63)
Query Neighborhood Hits	135	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P35396, P37239	Gene names	Ppard, Nr1c2, Pparb
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1).

PPARA_HUMAN
θ value	1.98606e-31 (rank : 47)	NC score	0.917713 (rank : 58)
Query Neighborhood Hits	135	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q07869, Q16241, Q92486, Q92689, Q9Y3N1	Gene names	PPARA, NR1C1, PPAR
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

TR2_MOUSE
θ value	2.59387e-31 (rank : 48)	NC score	0.931758 (rank : 44)
Query Neighborhood Hits	135	Target Neighborhood Hits	100	Shared Neighborhood Hits	98
SwissProt Accessions	Q505F1, P97763, Q3UIJ7, Q4U1Z4, Q60927, Q62152, Q8VIJ3	Gene names	Nr2c1, Tr2, Tr2-11
Domain Architecture	No domain graphic available
Description	Orphan nuclear receptor TR2 (Testicular receptor 2) (mTR2).

ESR2_MOUSE
θ value	4.42448e-31 (rank : 49)	NC score	0.932285 (rank : 43)
Query Neighborhood Hits	135	Target Neighborhood Hits	110	Shared Neighborhood Hits	96
SwissProt Accessions	O08537, O35635, O70519	Gene names	Esr2, Estrb, Nr3a2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

ESR2_HUMAN
θ value	7.54701e-31 (rank : 50)	NC score	0.933663 (rank : 41)
Query Neighborhood Hits	135	Target Neighborhood Hits	110	Shared Neighborhood Hits	97
SwissProt Accessions	Q92731, O60608, O60685, O60702, O60703, O75583, O75584, Q86Z31, Q9UEV6, Q9UHD3, Q9UQK9	Gene names	ESR2, ESTRB, NR3A2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

PPARG_MOUSE
θ value	7.54701e-31 (rank : 51)	NC score	0.913299 (rank : 67)
Query Neighborhood Hits	135	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37238	Gene names	Pparg, Nr1c3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

NR1H2_MOUSE
θ value	9.8567e-31 (rank : 52)	NC score	0.916228 (rank : 62)
Query Neighborhood Hits	135	Target Neighborhood Hits	109	Shared Neighborhood Hits	97
SwissProt Accessions	Q60644	Gene names	Nr1h2, Lxrb, Rip15, Unr, Unr2
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Retinoid X receptor-interacting protein No.15).

PPARG_HUMAN
θ value	9.8567e-31 (rank : 53)	NC score	0.913666 (rank : 65)
Query Neighborhood Hits	135	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37231, O00684, O00710, O14515, Q15178, Q15179, Q15180, Q15832, Q86U60, Q96J12	Gene names	PPARG, NR1C3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

PPARA_MOUSE
θ value	1.28732e-30 (rank : 54)	NC score	0.916774 (rank : 60)
Query Neighborhood Hits	135	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	P23204	Gene names	Ppara, Nr1c1, Ppar
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

PPARD_HUMAN
θ value	1.6813e-30 (rank : 55)	NC score	0.916281 (rank : 61)
Query Neighborhood Hits	135	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q03181, Q7Z5K0, Q9BUD4	Gene names	PPARD, NR1C2, PPARB
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1) (NUCI).

NR5A2_MOUSE
θ value	2.68423e-28 (rank : 56)	NC score	0.923030 (rank : 53)
Query Neighborhood Hits	135	Target Neighborhood Hits	107	Shared Neighborhood Hits	98
SwissProt Accessions	P45448	Gene names	Nr5a2, Lrh1
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Liver receptor homolog 1) (LRH-1).

TR2_HUMAN
θ value	7.80994e-28 (rank : 57)	NC score	0.929548 (rank : 47)
Query Neighborhood Hits	135	Target Neighborhood Hits	110	Shared Neighborhood Hits	98
SwissProt Accessions	P13056	Gene names	NR2C1, TR2
Domain Architecture
Description	Orphan nuclear receptor TR2 (Testicular receptor 2).

NR1H4_HUMAN
θ value	1.73987e-27 (rank : 58)	NC score	0.922727 (rank : 54)
Query Neighborhood Hits	135	Target Neighborhood Hits	112	Shared Neighborhood Hits	98
SwissProt Accessions	Q96RI1, Q8NFP5, Q8NFP6, Q92943	Gene names	NR1H4, BAR, FXR, HRR1, RIP14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

THA_HUMAN
θ value	2.96777e-27 (rank : 59)	NC score	0.911241 (rank : 69)
Query Neighborhood Hits	135	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	P10827, P21205, Q8N6A1, Q96H73	Gene names	THRA, ERBA1, NR1A1, THRA1
Domain Architecture
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1) (EAR-7) (EAR7).

THA_MOUSE
θ value	2.96777e-27 (rank : 60)	NC score	0.911244 (rank : 68)
Query Neighborhood Hits	135	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	P63058, P10685, P15827, P16416, P37241, Q63107, Q63195, Q63196, Q99146	Gene names	Thra, C-erba-alpha, Nr1a1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1).

NR1I3_HUMAN
θ value	1.47289e-26 (rank : 61)	NC score	0.923605 (rank : 52)
Query Neighborhood Hits	135	Target Neighborhood Hits	107	Shared Neighborhood Hits	98
SwissProt Accessions	Q14994	Gene names	NR1I3, CAR
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Constitutive activator of retinoid response) (Constitutive active response) (Orphan nuclear receptor MB67).

NR1H4_MOUSE
θ value	1.92365e-26 (rank : 62)	NC score	0.921977 (rank : 55)
Query Neighborhood Hits	135	Target Neighborhood Hits	113	Shared Neighborhood Hits	98
SwissProt Accessions	Q60641, Q60642, Q60643	Gene names	Nr1h4, Bar, Fxr, Rip14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

NR5A2_HUMAN
θ value	4.28545e-26 (rank : 63)	NC score	0.919816 (rank : 56)
Query Neighborhood Hits	135	Target Neighborhood Hits	112	Shared Neighborhood Hits	98
SwissProt Accessions	O00482, O95642	Gene names	NR5A2, B1F, CPF, FTF
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Alpha-1-fetoprotein transcription factor) (Hepatocytic transcription factor) (B1-binding factor) (hB1F) (CYP7A promoter-binding factor) (Liver receptor homolog 1) (LRH-1).

THB1_HUMAN
θ value	5.59698e-26 (rank : 64)	NC score	0.905371 (rank : 73)
Query Neighborhood Hits	135	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P10828, Q13986	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture
Description	Thyroid hormone receptor beta-1.

THB2_HUMAN
θ value	5.59698e-26 (rank : 65)	NC score	0.905807 (rank : 72)
Query Neighborhood Hits	135	Target Neighborhood Hits	104	Shared Neighborhood Hits	98
SwissProt Accessions	P37243	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor beta-2.

RORG_HUMAN
θ value	7.30988e-26 (rank : 66)	NC score	0.900192 (rank : 80)
Query Neighborhood Hits	135	Target Neighborhood Hits	119	Shared Neighborhood Hits	97
SwissProt Accessions	P51449, Q8N5V7, Q8NCY8	Gene names	RORC, NR1F3, RORG, RZRG
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma).

RORA_MOUSE
θ value	9.54697e-26 (rank : 67)	NC score	0.899381 (rank : 82)
Query Neighborhood Hits	135	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P51448, P70283, P97741, P97773, Q923G1	Gene names	Rora, Nr1f1, Rzra
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

NR1H2_HUMAN
θ value	1.24688e-25 (rank : 68)	NC score	0.908055 (rank : 70)
Query Neighborhood Hits	135	Target Neighborhood Hits	114	Shared Neighborhood Hits	96
SwissProt Accessions	P55055, Q12970	Gene names	NR1H2, LXRB, NER, UNR
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Nuclear receptor NER).

RORG_MOUSE
θ value	1.24688e-25 (rank : 69)	NC score	0.903516 (rank : 77)
Query Neighborhood Hits	135	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	P51450, Q61027, Q91YT5, Q9QXD9, Q9R177	Gene names	Rorc, Nr1f3, Rorg, Thor
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma) (Thymus orphan receptor) (TOR).

RORB_HUMAN
θ value	1.62847e-25 (rank : 70)	NC score	0.900846 (rank : 78)
Query Neighborhood Hits	135	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	Q92753, Q8WX73	Gene names	RORB, NR1F2, RZRB
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORB_MOUSE
θ value	1.62847e-25 (rank : 71)	NC score	0.900641 (rank : 79)
Query Neighborhood Hits	135	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	Q8R1B8	Gene names	Rorb, Nr1f2
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

THB1_MOUSE
θ value	3.62785e-25 (rank : 72)	NC score	0.904015 (rank : 75)
Query Neighborhood Hits	135	Target Neighborhood Hits	105	Shared Neighborhood Hits	98
SwissProt Accessions	P37242	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-1.

THB2_MOUSE
θ value	3.62785e-25 (rank : 73)	NC score	0.903886 (rank : 76)
Query Neighborhood Hits	135	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P37244	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-2.

RORA_HUMAN
θ value	8.08199e-25 (rank : 74)	NC score	0.899456 (rank : 81)
Query Neighborhood Hits	135	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P35398, P35397, P35399, P45445, Q96H83	Gene names	RORA, NR1F1, RZRA
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

NR1I3_MOUSE
θ value	1.37858e-24 (rank : 75)	NC score	0.919234 (rank : 57)
Query Neighborhood Hits	135	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	O35627, O35628	Gene names	Nr1i3, Car
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67).

ANDR_HUMAN
θ value	1.80048e-24 (rank : 76)	NC score	0.878356 (rank : 89)
Query Neighborhood Hits	135	Target Neighborhood Hits	126	Shared Neighborhood Hits	94
SwissProt Accessions	P10275	Gene names	AR, DHTR, NR3C4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

ANDR_MOUSE
θ value	8.93572e-24 (rank : 77)	NC score	0.879705 (rank : 88)
Query Neighborhood Hits	135	Target Neighborhood Hits	133	Shared Neighborhood Hits	94
SwissProt Accessions	P19091	Gene names	Ar, Nr3c4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

GCR_HUMAN
θ value	4.43474e-23 (rank : 78)	NC score	0.881981 (rank : 87)
Query Neighborhood Hits	135	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P04150, P04151, Q53EP5, Q6N0A4	Gene names	NR3C1, GRL
Domain Architecture
Description	Glucocorticoid receptor (GR).

NR1D2_MOUSE
θ value	4.43474e-23 (rank : 79)	NC score	0.904614 (rank : 74)
Query Neighborhood Hits	135	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	Q60674, Q60646	Gene names	Nr1d2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (Orphan nuclear receptor RVR).

NR1D2_HUMAN
θ value	2.87452e-22 (rank : 80)	NC score	0.906845 (rank : 71)
Query Neighborhood Hits	135	Target Neighborhood Hits	115	Shared Neighborhood Hits	94
SwissProt Accessions	Q14995, O00402, Q86XD4	Gene names	NR1D2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (EAR-1R) (Orphan nuclear hormone receptor BD73).

MCR_MOUSE
θ value	8.36355e-22 (rank : 81)	NC score	0.869192 (rank : 93)
Query Neighborhood Hits	135	Target Neighborhood Hits	162	Shared Neighborhood Hits	94
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

MCR_HUMAN
θ value	1.09232e-21 (rank : 82)	NC score	0.873100 (rank : 91)
Query Neighborhood Hits	135	Target Neighborhood Hits	149	Shared Neighborhood Hits	95
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

NR1D1_HUMAN
θ value	1.09232e-21 (rank : 83)	NC score	0.913548 (rank : 66)
Query Neighborhood Hits	135	Target Neighborhood Hits	140	Shared Neighborhood Hits	95
SwissProt Accessions	P20393, Q15304	Gene names	NR1D1, EAR1, HREV, THRAL
Domain Architecture
Description	Orphan nuclear receptor NR1D1 (V-erbA-related protein EAR-1) (Rev- erbA-alpha).

STF1_HUMAN
θ value	1.09232e-21 (rank : 84)	NC score	0.914042 (rank : 64)
Query Neighborhood Hits	135	Target Neighborhood Hits	132	Shared Neighborhood Hits	99
SwissProt Accessions	Q13285, O15196	Gene names	NR5A1, AD4BP, FTZF1, SF1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1).

STF1_MOUSE
θ value	1.09232e-21 (rank : 85)	NC score	0.916901 (rank : 59)
Query Neighborhood Hits	135	Target Neighborhood Hits	137	Shared Neighborhood Hits	100
SwissProt Accessions	P33242	Gene names	Nr5a1, Ftzf1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1) (Embryonal LTR-binding protein) (ELP) (Embryonal long terminal repeat- binding protein) (Steroid hydroxylase positive regulator).

NR6A1_HUMAN
θ value	1.42661e-21 (rank : 86)	NC score	0.927764 (rank : 48)
Query Neighborhood Hits	135	Target Neighborhood Hits	108	Shared Neighborhood Hits	98
SwissProt Accessions	Q15406, O00551, O00603, Q8NHQ0, Q92898, Q99802	Gene names	NR6A1, GCNF
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

NR6A1_MOUSE
θ value	1.42661e-21 (rank : 87)	NC score	0.926703 (rank : 49)
Query Neighborhood Hits	135	Target Neighborhood Hits	110	Shared Neighborhood Hits	98
SwissProt Accessions	Q64249	Gene names	Nr6a1, Gcnf
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

PRGR_HUMAN
θ value	2.43343e-21 (rank : 88)	NC score	0.870988 (rank : 92)
Query Neighborhood Hits	135	Target Neighborhood Hits	163	Shared Neighborhood Hits	98
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

GCR_MOUSE
θ value	3.17815e-21 (rank : 89)	NC score	0.874941 (rank : 90)
Query Neighborhood Hits	135	Target Neighborhood Hits	117	Shared Neighborhood Hits	94
SwissProt Accessions	P06537, Q61628, Q61629	Gene names	Nr3c1, Grl, Grl1
Domain Architecture
Description	Glucocorticoid receptor (GR).

PRGR_MOUSE
θ value	7.0802e-21 (rank : 90)	NC score	0.865277 (rank : 94)
Query Neighborhood Hits	135	Target Neighborhood Hits	286	Shared Neighborhood Hits	103
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

SHP_HUMAN
θ value	1.74391e-19 (rank : 91)	NC score	0.646053 (rank : 95)
Query Neighborhood Hits	135	Target Neighborhood Hits	57	Shared Neighborhood Hits	56
SwissProt Accessions	Q15466, Q5QP36	Gene names	NR0B2, SHP
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

SHP_MOUSE
θ value	1.24977e-17 (rank : 92)	NC score	0.638957 (rank : 96)
Query Neighborhood Hits	135	Target Neighborhood Hits	53	Shared Neighborhood Hits	53
SwissProt Accessions	Q62227, Q53Z53	Gene names	Nr0b2, Shp
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

VDR_HUMAN
θ value	2.7842e-17 (rank : 93)	NC score	0.897157 (rank : 84)
Query Neighborhood Hits	135	Target Neighborhood Hits	112	Shared Neighborhood Hits	96
SwissProt Accessions	P11473	Gene names	VDR, NR1I1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

VDR_MOUSE
θ value	2.7842e-17 (rank : 94)	NC score	0.898703 (rank : 83)
Query Neighborhood Hits	135	Target Neighborhood Hits	103	Shared Neighborhood Hits	96
SwissProt Accessions	P48281	Gene names	Vdr, Nr1i1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

PXR_MOUSE
θ value	3.07829e-16 (rank : 95)	NC score	0.896035 (rank : 85)
Query Neighborhood Hits	135	Target Neighborhood Hits	107	Shared Neighborhood Hits	97
SwissProt Accessions	O54915	Gene names	Nr1i2, Pxr
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor).

PXR_HUMAN
θ value	4.02038e-16 (rank : 96)	NC score	0.893920 (rank : 86)
Query Neighborhood Hits	135	Target Neighborhood Hits	107	Shared Neighborhood Hits	97
SwissProt Accessions	O75469, Q96AC7, Q9UJ22, Q9UJ23, Q9UJ24, Q9UJ25, Q9UJ26, Q9UJ27	Gene names	NR1I2, PXR
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor) (Orphan nuclear receptor PAR1) (Steroid and xenobiotic receptor) (SXR).

DAX1_HUMAN
θ value	1.68911e-14 (rank : 97)	NC score	0.594189 (rank : 98)
Query Neighborhood Hits	135	Target Neighborhood Hits	65	Shared Neighborhood Hits	59
SwissProt Accessions	P51843, Q96F69	Gene names	NR0B1, AHC, DAX1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1) (DSS-AHC critical region on the X chromosome protein 1).

DAX1_MOUSE
θ value	9.26847e-13 (rank : 98)	NC score	0.612513 (rank : 97)
Query Neighborhood Hits	135	Target Neighborhood Hits	70	Shared Neighborhood Hits	60
SwissProt Accessions	Q61066, O09068, O09147	Gene names	Nr0b1, Ahch, Dax1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1).

CO5A2_HUMAN
θ value	0.0736092 (rank : 99)	NC score	0.023985 (rank : 99)
Query Neighborhood Hits	135	Target Neighborhood Hits	760	Shared Neighborhood Hits	33
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

ZN341_HUMAN
θ value	0.163984 (rank : 100)	NC score	-0.003922 (rank : 133)
Query Neighborhood Hits	135	Target Neighborhood Hits	803	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BYN7, Q5JXM8, Q96ST5	Gene names	ZNF341
Domain Architecture	No domain graphic available
Description	Zinc finger protein 341.

CO4A2_HUMAN
θ value	0.365318 (rank : 101)	NC score	0.020684 (rank : 102)
Query Neighborhood Hits	135	Target Neighborhood Hits	454	Shared Neighborhood Hits	27
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

MBB1A_HUMAN
θ value	0.365318 (rank : 102)	NC score	0.014508 (rank : 111)
Query Neighborhood Hits	135	Target Neighborhood Hits	665	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

CSKI1_HUMAN
θ value	0.62314 (rank : 103)	NC score	0.004378 (rank : 123)
Query Neighborhood Hits	135	Target Neighborhood Hits	997	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CO4A2_MOUSE
θ value	0.813845 (rank : 104)	NC score	0.017602 (rank : 107)
Query Neighborhood Hits	135	Target Neighborhood Hits	492	Shared Neighborhood Hits	27
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CO9A2_HUMAN
θ value	1.06291 (rank : 105)	NC score	0.020793 (rank : 101)
Query Neighborhood Hits	135	Target Neighborhood Hits	261	Shared Neighborhood Hits	24
SwissProt Accessions	Q14055	Gene names	COL9A2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

ZFP28_HUMAN
θ value	1.06291 (rank : 106)	NC score	-0.006689 (rank : 134)
Query Neighborhood Hits	135	Target Neighborhood Hits	843	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NHY6, Q9BY30, Q9P2B6	Gene names	ZFP28, KIAA1431
Domain Architecture
Description	Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6).

CO9A1_MOUSE
θ value	1.38821 (rank : 107)	NC score	0.022381 (rank : 100)
Query Neighborhood Hits	135	Target Neighborhood Hits	477	Shared Neighborhood Hits	30
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO2A1_HUMAN
θ value	1.81305 (rank : 108)	NC score	0.019397 (rank : 103)
Query Neighborhood Hits	135	Target Neighborhood Hits	486	Shared Neighborhood Hits	29
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO2A1_MOUSE
θ value	1.81305 (rank : 109)	NC score	0.018698 (rank : 104)
Query Neighborhood Hits	135	Target Neighborhood Hits	483	Shared Neighborhood Hits	27
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

FOXJ3_MOUSE
θ value	2.36792 (rank : 110)	NC score	0.003451 (rank : 126)
Query Neighborhood Hits	135	Target Neighborhood Hits	190	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BUR3, Q3UTD8	Gene names	Foxj3, Kiaa1041
Domain Architecture
Description	Forkhead box protein J3.

PCLO_MOUSE
θ value	2.36792 (rank : 111)	NC score	0.000471 (rank : 129)
Query Neighborhood Hits	135	Target Neighborhood Hits	2275	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RIN3_HUMAN
θ value	2.36792 (rank : 112)	NC score	0.010135 (rank : 114)
Query Neighborhood Hits	135	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

ZN516_MOUSE
θ value	2.36792 (rank : 113)	NC score	-0.003391 (rank : 132)
Query Neighborhood Hits	135	Target Neighborhood Hits	1197	Shared Neighborhood Hits	29
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

FOXJ3_HUMAN
θ value	3.0926 (rank : 114)	NC score	0.003196 (rank : 127)
Query Neighborhood Hits	135	Target Neighborhood Hits	177	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPW0, Q9NSS7	Gene names	FOXJ3, KIAA1041
Domain Architecture
Description	Forkhead box protein J3.

OXRP_HUMAN
θ value	3.0926 (rank : 115)	NC score	0.006340 (rank : 119)
Query Neighborhood Hits	135	Target Neighborhood Hits	544	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

ZN687_HUMAN
θ value	3.0926 (rank : 116)	NC score	-0.000713 (rank : 131)
Query Neighborhood Hits	135	Target Neighborhood Hits	1244	Shared Neighborhood Hits	29
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

CEND_HUMAN
θ value	4.03905 (rank : 117)	NC score	0.015161 (rank : 110)
Query Neighborhood Hits	135	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N111, Q9NYM6	Gene names	CEND1, BM88
Domain Architecture	No domain graphic available
Description	Cell cycle exit and neuronal differentiation protein 1 (BM88 antigen).

CO4A1_HUMAN
θ value	4.03905 (rank : 118)	NC score	0.018348 (rank : 106)
Query Neighborhood Hits	135	Target Neighborhood Hits	425	Shared Neighborhood Hits	26
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CO7A1_HUMAN
θ value	4.03905 (rank : 119)	NC score	0.009704 (rank : 116)
Query Neighborhood Hits	135	Target Neighborhood Hits	807	Shared Neighborhood Hits	28
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

COJA1_HUMAN
θ value	4.03905 (rank : 120)	NC score	0.016617 (rank : 108)
Query Neighborhood Hits	135	Target Neighborhood Hits	323	Shared Neighborhood Hits	26
SwissProt Accessions	Q14993, Q00559, Q05850, Q12885, Q13676, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2	Gene names	COL19A1
Domain Architecture
Description	Collagen alpha-1(XIX) chain precursor (Collagen alpha-1(Y) chain).

MTSS1_HUMAN
θ value	4.03905 (rank : 121)	NC score	0.007623 (rank : 117)
Query Neighborhood Hits	135	Target Neighborhood Hits	504	Shared Neighborhood Hits	17
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

CO5A3_HUMAN
θ value	5.27518 (rank : 122)	NC score	0.018610 (rank : 105)
Query Neighborhood Hits	135	Target Neighborhood Hits	433	Shared Neighborhood Hits	29
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

COBA2_MOUSE
θ value	6.88961 (rank : 123)	NC score	0.012347 (rank : 112)
Query Neighborhood Hits	135	Target Neighborhood Hits	501	Shared Neighborhood Hits	28
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

COIA1_MOUSE
θ value	6.88961 (rank : 124)	NC score	0.011129 (rank : 113)
Query Neighborhood Hits	135	Target Neighborhood Hits	481	Shared Neighborhood Hits	25
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

PARD3_HUMAN
θ value	6.88961 (rank : 125)	NC score	0.003924 (rank : 125)
Query Neighborhood Hits	135	Target Neighborhood Hits	312	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

CJ064_HUMAN
θ value	8.99809 (rank : 126)	NC score	0.005530 (rank : 121)
Query Neighborhood Hits	135	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZS81, Q8N4A3	Gene names	C10orf64
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf64.

CLAP2_MOUSE
θ value	8.99809 (rank : 127)	NC score	0.006434 (rank : 118)
Query Neighborhood Hits	135	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BRT1, Q8CHE3, Q99JI3, Q9DB80	Gene names	Clasp2, Kiaa0627
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2).

CO9A1_HUMAN
θ value	8.99809 (rank : 128)	NC score	0.015800 (rank : 109)
Query Neighborhood Hits	135	Target Neighborhood Hits	420	Shared Neighborhood Hits	30
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CSKI2_MOUSE
θ value	8.99809 (rank : 129)	NC score	-0.000667 (rank : 130)
Query Neighborhood Hits	135	Target Neighborhood Hits	812	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

IRS2_MOUSE
θ value	8.99809 (rank : 130)	NC score	0.004216 (rank : 124)
Query Neighborhood Hits	135	Target Neighborhood Hits	248	Shared Neighborhood Hits	12
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

OGFR_HUMAN
θ value	8.99809 (rank : 131)	NC score	0.009847 (rank : 115)
Query Neighborhood Hits	135	Target Neighborhood Hits	1582	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PKN3_MOUSE
θ value	8.99809 (rank : 132)	NC score	-0.008378 (rank : 135)
Query Neighborhood Hits	135	Target Neighborhood Hits	1009	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

RAI1_MOUSE
θ value	8.99809 (rank : 133)	NC score	0.005612 (rank : 120)
Query Neighborhood Hits	135	Target Neighborhood Hits	344	Shared Neighborhood Hits	9
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

SON_MOUSE
θ value	8.99809 (rank : 134)	NC score	0.004601 (rank : 122)
Query Neighborhood Hits	135	Target Neighborhood Hits	957	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

YAP1_HUMAN
θ value	8.99809 (rank : 135)	NC score	0.002605 (rank : 128)
Query Neighborhood Hits	135	Target Neighborhood Hits	173	Shared Neighborhood Hits	5
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

Hits sorted by NC score

COT2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	135	Target Neighborhood Hits	135	Shared Neighborhood Hits	135
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT2_MOUSE
NC score	0.999962 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	135	Target Neighborhood Hits	135	Shared Neighborhood Hits	135
SwissProt Accessions	P43135	Gene names	Nr2f2, Aporp1, Arp-1, Arp1, Tfcoup2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT1_MOUSE
NC score	0.998128 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	135	Target Neighborhood Hits	160	Shared Neighborhood Hits	114
SwissProt Accessions	Q60632, Q61438	Gene names	Nr2f1, Erbal3, Tfcoup1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I).

COT1_HUMAN
NC score	0.998028 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	135	Target Neighborhood Hits	159	Shared Neighborhood Hits	116
SwissProt Accessions	P10589	Gene names	NR2F1, EAR3, ERBAL3, TFCOUP1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I) (V-ERBA-related protein EAR-3).

EAR2_HUMAN
NC score	0.996795 (rank : 5)	θ value	1.28961e-139 (rank : 5)
Query Neighborhood Hits	135	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P10588, Q9BUE8	Gene names	NR2F6, EAR2, ERBAL2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

EAR2_MOUSE
NC score	0.996728 (rank : 6)	θ value	1.74296e-136 (rank : 6)
Query Neighborhood Hits	135	Target Neighborhood Hits	104	Shared Neighborhood Hits	98
SwissProt Accessions	P43136, Q61504	Gene names	Nr2f6, Ear-2, Ear2, Erbal2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

NR2E3_HUMAN
NC score	0.985767 (rank : 7)	θ value	4.37348e-71 (rank : 11)
Query Neighborhood Hits	135	Target Neighborhood Hits	102	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y5X4, Q9UHM4	Gene names	NR2E3, PNR, RNR
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

NR2E3_MOUSE
NC score	0.985053 (rank : 8)	θ value	8.24801e-70 (rank : 12)
Query Neighborhood Hits	135	Target Neighborhood Hits	113	Shared Neighborhood Hits	98
SwissProt Accessions	Q9QXZ7	Gene names	Nr2e3, Pnr, Rnr
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

NR2E1_HUMAN
NC score	0.983911 (rank : 9)	θ value	1.71981e-67 (rank : 15)
Query Neighborhood Hits	135	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y466	Gene names	NR2E1, TLX
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (hTll).

NR2E1_MOUSE
NC score	0.983828 (rank : 10)	θ value	1.71981e-67 (rank : 16)
Query Neighborhood Hits	135	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	Q64104	Gene names	Nr2e1, Tll, Tlx
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (mTll).

RXRG_HUMAN
NC score	0.980861 (rank : 11)	θ value	9.41505e-74 (rank : 9)
Query Neighborhood Hits	135	Target Neighborhood Hits	114	Shared Neighborhood Hits	100
SwissProt Accessions	P48443	Gene names	RXRG, NR2B3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

RXRG_MOUSE
NC score	0.980648 (rank : 12)	θ value	6.10265e-73 (rank : 10)
Query Neighborhood Hits	135	Target Neighborhood Hits	113	Shared Neighborhood Hits	98
SwissProt Accessions	P28705	Gene names	Rxrg, Nr2b3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

RXRA_MOUSE
NC score	0.980144 (rank : 13)	θ value	2.47765e-74 (rank : 7)
Query Neighborhood Hits	135	Target Neighborhood Hits	129	Shared Neighborhood Hits	98
SwissProt Accessions	P28700	Gene names	Rxra, Nr2b1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

RXRA_HUMAN
NC score	0.977225 (rank : 14)	θ value	3.23591e-74 (rank : 8)
Query Neighborhood Hits	135	Target Neighborhood Hits	223	Shared Neighborhood Hits	101
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

HNF4G_HUMAN
NC score	0.976621 (rank : 15)	θ value	3.59435e-57 (rank : 20)
Query Neighborhood Hits	135	Target Neighborhood Hits	100	Shared Neighborhood Hits	98
SwissProt Accessions	Q14541, Q9UH81, Q9UIS6	Gene names	HNF4G, NR2A2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

HNF4A_MOUSE
NC score	0.976463 (rank : 16)	θ value	1.7238e-59 (rank : 17)
Query Neighborhood Hits	135	Target Neighborhood Hits	103	Shared Neighborhood Hits	99
SwissProt Accessions	P49698	Gene names	Hnf4a, Hnf-4, Hnf4, Nr2a1, Tcf14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

HNF4G_MOUSE
NC score	0.976328 (rank : 17)	θ value	2.10721e-57 (rank : 19)
Query Neighborhood Hits	135	Target Neighborhood Hits	101	Shared Neighborhood Hits	98
SwissProt Accessions	Q9WUU6	Gene names	Hnf4g, Nr2a2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

HNF4A_HUMAN
NC score	0.975961 (rank : 18)	θ value	3.25095e-58 (rank : 18)
Query Neighborhood Hits	135	Target Neighborhood Hits	105	Shared Neighborhood Hits	99
SwissProt Accessions	P41235, O00659, O00723, Q14540, Q92653, Q92654, Q92655, Q99864, Q9NQH0	Gene names	HNF4A, HNF4, NR2A1, TCF14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

RXRB_MOUSE
NC score	0.975931 (rank : 19)	θ value	6.98233e-69 (rank : 14)
Query Neighborhood Hits	135	Target Neighborhood Hits	230	Shared Neighborhood Hits	102
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

RXRB_HUMAN
NC score	0.971892 (rank : 20)	θ value	3.13423e-69 (rank : 13)
Query Neighborhood Hits	135	Target Neighborhood Hits	280	Shared Neighborhood Hits	107
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

ERR2_MOUSE
NC score	0.957033 (rank : 21)	θ value	9.48078e-50 (rank : 22)
Query Neighborhood Hits	135	Target Neighborhood Hits	109	Shared Neighborhood Hits	98
SwissProt Accessions	Q61539, O09067, O09146	Gene names	Esrrb, Err-2, Err2, Nr3b2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2).

ERR3_HUMAN
NC score	0.956791 (rank : 22)	θ value	1.36902e-48 (rank : 23)
Query Neighborhood Hits	135	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P62508, O75454, O96021, Q68DA0, Q6P274, Q6PK28, Q6TS38, Q9R1F3, Q9UNJ4	Gene names	ESRRG, ERR3, ERRG2, KIAA0832, NR3B3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (ERR gamma-2).

ERR3_MOUSE
NC score	0.956791 (rank : 23)	θ value	1.36902e-48 (rank : 24)
Query Neighborhood Hits	135	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P62509, O75454, O96021, Q8CHC9, Q9R1F3	Gene names	Esrrg, Err3, Kiaa0832, Nr3b3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3).

ERR2_HUMAN
NC score	0.954597 (rank : 24)	θ value	9.48078e-50 (rank : 21)
Query Neighborhood Hits	135	Target Neighborhood Hits	108	Shared Neighborhood Hits	98
SwissProt Accessions	O95718, Q9HCB4	Gene names	ESRRB, ERRB2, NR3B2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2) (ERR beta-2).

ERR1_HUMAN
NC score	0.953815 (rank : 25)	θ value	1.73182e-43 (rank : 25)
Query Neighborhood Hits	135	Target Neighborhood Hits	157	Shared Neighborhood Hits	102
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

NR4A2_MOUSE
NC score	0.939643 (rank : 26)	θ value	1.91475e-42 (rank : 27)
Query Neighborhood Hits	135	Target Neighborhood Hits	121	Shared Neighborhood Hits	97
SwissProt Accessions	Q06219, O08690	Gene names	Nr4a2, Nurr1
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (NUR- related factor 1).

NR4A1_HUMAN
NC score	0.939611 (rank : 27)	θ value	1.3722e-40 (rank : 28)
Query Neighborhood Hits	135	Target Neighborhood Hits	133	Shared Neighborhood Hits	96
SwissProt Accessions	P22736	Gene names	NR4A1, GFRP1, HMR, NAK1
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Early response protein NAK1) (TR3 orphan receptor) (ST-59).

NR4A2_HUMAN
NC score	0.939601 (rank : 28)	θ value	1.91475e-42 (rank : 26)
Query Neighborhood Hits	135	Target Neighborhood Hits	120	Shared Neighborhood Hits	97
SwissProt Accessions	P43354, Q16311	Gene names	NR4A2, NOT, NURR1, TINUR
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (Immediate-early response protein NOT) (Transcriptionally-inducible nuclear receptor).

NR4A1_MOUSE
NC score	0.938328 (rank : 29)	θ value	8.89434e-40 (rank : 29)
Query Neighborhood Hits	135	Target Neighborhood Hits	128	Shared Neighborhood Hits	94
SwissProt Accessions	P12813	Gene names	Nr4a1, Gfrp, Hmr, N10, Nur77
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Nuclear hormone receptor NUR/77) (N10 nuclear protein).

NR4A3_MOUSE
NC score	0.937225 (rank : 30)	θ value	1.32909e-35 (rank : 38)
Query Neighborhood Hits	135	Target Neighborhood Hits	127	Shared Neighborhood Hits	96
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

NR4A3_HUMAN
NC score	0.935939 (rank : 31)	θ value	3.27365e-34 (rank : 41)
Query Neighborhood Hits	135	Target Neighborhood Hits	131	Shared Neighborhood Hits	98
SwissProt Accessions	Q92570, Q12935, Q14979, Q16420, Q4VXA9, Q9UEK2, Q9UEK3	Gene names	NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1) (Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphan receptor).

TR4_HUMAN
NC score	0.934718 (rank : 32)	θ value	5.0505e-35 (rank : 39)
Query Neighborhood Hits	135	Target Neighborhood Hits	117	Shared Neighborhood Hits	98
SwissProt Accessions	P49116, P55092	Gene names	NR2C2, TAK1, TR4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

TR4_MOUSE
NC score	0.934374 (rank : 33)	θ value	6.59618e-35 (rank : 40)
Query Neighborhood Hits	135	Target Neighborhood Hits	115	Shared Neighborhood Hits	98
SwissProt Accessions	P49117, P55093	Gene names	Nr2c2, Mtr2r1, Tak1, Tr4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

RARA_HUMAN
NC score	0.934284 (rank : 34)	θ value	4.88048e-38 (rank : 36)
Query Neighborhood Hits	135	Target Neighborhood Hits	118	Shared Neighborhood Hits	96
SwissProt Accessions	P10276, P78456, Q13440, Q13441, Q9NQS0	Gene names	RARA, NR1B1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARG2_HUMAN
NC score	0.934209 (rank : 35)	θ value	8.89434e-40 (rank : 31)
Query Neighborhood Hits	135	Target Neighborhood Hits	109	Shared Neighborhood Hits	95
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

RARA_MOUSE
NC score	0.934181 (rank : 36)	θ value	1.08726e-37 (rank : 37)
Query Neighborhood Hits	135	Target Neighborhood Hits	113	Shared Neighborhood Hits	96
SwissProt Accessions	P11416, P22603	Gene names	Rara, Nr1b1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARG1_HUMAN
NC score	0.934059 (rank : 37)	θ value	8.89434e-40 (rank : 30)
Query Neighborhood Hits	135	Target Neighborhood Hits	107	Shared Neighborhood Hits	95
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARG2_MOUSE
NC score	0.933771 (rank : 38)	θ value	7.52953e-39 (rank : 33)
Query Neighborhood Hits	135	Target Neighborhood Hits	114	Shared Neighborhood Hits	96
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

RARB_HUMAN
NC score	0.933748 (rank : 39)	θ value	9.83387e-39 (rank : 34)
Query Neighborhood Hits	135	Target Neighborhood Hits	118	Shared Neighborhood Hits	94
SwissProt Accessions	P10826, P12891, Q00989, Q15298, Q9UN48	Gene names	RARB, HAP, NR1B2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta) (RAR-epsilon) (HBV-activated protein).

RARB_MOUSE
NC score	0.933685 (rank : 40)	θ value	3.73686e-38 (rank : 35)
Query Neighborhood Hits	135	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	P22605, P11417, P22604	Gene names	Rarb, Nr1b2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta).

ESR2_HUMAN
NC score	0.933663 (rank : 41)	θ value	7.54701e-31 (rank : 50)
Query Neighborhood Hits	135	Target Neighborhood Hits	110	Shared Neighborhood Hits	97
SwissProt Accessions	Q92731, O60608, O60685, O60702, O60703, O75583, O75584, Q86Z31, Q9UEV6, Q9UHD3, Q9UQK9	Gene names	ESR2, ESTRB, NR3A2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

RARG1_MOUSE
NC score	0.933473 (rank : 42)	θ value	7.52953e-39 (rank : 32)
Query Neighborhood Hits	135	Target Neighborhood Hits	113	Shared Neighborhood Hits	96
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

ESR2_MOUSE
NC score	0.932285 (rank : 43)	θ value	4.42448e-31 (rank : 49)
Query Neighborhood Hits	135	Target Neighborhood Hits	110	Shared Neighborhood Hits	96
SwissProt Accessions	O08537, O35635, O70519	Gene names	Esr2, Estrb, Nr3a2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

TR2_MOUSE
NC score	0.931758 (rank : 44)	θ value	2.59387e-31 (rank : 48)
Query Neighborhood Hits	135	Target Neighborhood Hits	100	Shared Neighborhood Hits	98
SwissProt Accessions	Q505F1, P97763, Q3UIJ7, Q4U1Z4, Q60927, Q62152, Q8VIJ3	Gene names	Nr2c1, Tr2, Tr2-11
Domain Architecture	No domain graphic available
Description	Orphan nuclear receptor TR2 (Testicular receptor 2) (mTR2).

ESR1_MOUSE
NC score	0.929770 (rank : 45)	θ value	3.06405e-32 (rank : 42)
Query Neighborhood Hits	135	Target Neighborhood Hits	104	Shared Neighborhood Hits	95
SwissProt Accessions	P19785, Q9JJT5, Q9QY51, Q9QY52	Gene names	Esr1, Esr, Estr, Estra, Nr3a1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

ESR1_HUMAN
NC score	0.929653 (rank : 46)	θ value	4.00176e-32 (rank : 44)
Query Neighborhood Hits	135	Target Neighborhood Hits	105	Shared Neighborhood Hits	95
SwissProt Accessions	P03372, Q13511, Q14276, Q9NU51, Q9UDZ7, Q9UIS7	Gene names	ESR1, ESR, NR3A1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

TR2_HUMAN
NC score	0.929548 (rank : 47)	θ value	7.80994e-28 (rank : 57)
Query Neighborhood Hits	135	Target Neighborhood Hits	110	Shared Neighborhood Hits	98
SwissProt Accessions	P13056	Gene names	NR2C1, TR2
Domain Architecture
Description	Orphan nuclear receptor TR2 (Testicular receptor 2).

NR6A1_HUMAN
NC score	0.927764 (rank : 48)	θ value	1.42661e-21 (rank : 86)
Query Neighborhood Hits	135	Target Neighborhood Hits	108	Shared Neighborhood Hits	98
SwissProt Accessions	Q15406, O00551, O00603, Q8NHQ0, Q92898, Q99802	Gene names	NR6A1, GCNF
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

NR6A1_MOUSE
NC score	0.926703 (rank : 49)	θ value	1.42661e-21 (rank : 87)
Query Neighborhood Hits	135	Target Neighborhood Hits	110	Shared Neighborhood Hits	98
SwissProt Accessions	Q64249	Gene names	Nr6a1, Gcnf
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

NR1H3_HUMAN
NC score	0.925613 (rank : 50)	θ value	4.00176e-32 (rank : 45)
Query Neighborhood Hits	135	Target Neighborhood Hits	104	Shared Neighborhood Hits	95
SwissProt Accessions	Q13133, Q96H87	Gene names	NR1H3, LXRA
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

NR1H3_MOUSE
NC score	0.924452 (rank : 51)	θ value	3.06405e-32 (rank : 43)
Query Neighborhood Hits	135	Target Neighborhood Hits	102	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z0Y9, Q9QUH7	Gene names	Nr1h3, Lxra
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

NR1I3_HUMAN
NC score	0.923605 (rank : 52)	θ value	1.47289e-26 (rank : 61)
Query Neighborhood Hits	135	Target Neighborhood Hits	107	Shared Neighborhood Hits	98
SwissProt Accessions	Q14994	Gene names	NR1I3, CAR
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Constitutive activator of retinoid response) (Constitutive active response) (Orphan nuclear receptor MB67).

NR5A2_MOUSE
NC score	0.923030 (rank : 53)	θ value	2.68423e-28 (rank : 56)
Query Neighborhood Hits	135	Target Neighborhood Hits	107	Shared Neighborhood Hits	98
SwissProt Accessions	P45448	Gene names	Nr5a2, Lrh1
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Liver receptor homolog 1) (LRH-1).

NR1H4_HUMAN
NC score	0.922727 (rank : 54)	θ value	1.73987e-27 (rank : 58)
Query Neighborhood Hits	135	Target Neighborhood Hits	112	Shared Neighborhood Hits	98
SwissProt Accessions	Q96RI1, Q8NFP5, Q8NFP6, Q92943	Gene names	NR1H4, BAR, FXR, HRR1, RIP14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

NR1H4_MOUSE
NC score	0.921977 (rank : 55)	θ value	1.92365e-26 (rank : 62)
Query Neighborhood Hits	135	Target Neighborhood Hits	113	Shared Neighborhood Hits	98
SwissProt Accessions	Q60641, Q60642, Q60643	Gene names	Nr1h4, Bar, Fxr, Rip14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

NR5A2_HUMAN
NC score	0.919816 (rank : 56)	θ value	4.28545e-26 (rank : 63)
Query Neighborhood Hits	135	Target Neighborhood Hits	112	Shared Neighborhood Hits	98
SwissProt Accessions	O00482, O95642	Gene names	NR5A2, B1F, CPF, FTF
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Alpha-1-fetoprotein transcription factor) (Hepatocytic transcription factor) (B1-binding factor) (hB1F) (CYP7A promoter-binding factor) (Liver receptor homolog 1) (LRH-1).

NR1I3_MOUSE
NC score	0.919234 (rank : 57)	θ value	1.37858e-24 (rank : 75)
Query Neighborhood Hits	135	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	O35627, O35628	Gene names	Nr1i3, Car
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67).

PPARA_HUMAN
NC score	0.917713 (rank : 58)	θ value	1.98606e-31 (rank : 47)
Query Neighborhood Hits	135	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q07869, Q16241, Q92486, Q92689, Q9Y3N1	Gene names	PPARA, NR1C1, PPAR
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

STF1_MOUSE
NC score	0.916901 (rank : 59)	θ value	1.09232e-21 (rank : 85)
Query Neighborhood Hits	135	Target Neighborhood Hits	137	Shared Neighborhood Hits	100
SwissProt Accessions	P33242	Gene names	Nr5a1, Ftzf1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1) (Embryonal LTR-binding protein) (ELP) (Embryonal long terminal repeat- binding protein) (Steroid hydroxylase positive regulator).

PPARA_MOUSE
NC score	0.916774 (rank : 60)	θ value	1.28732e-30 (rank : 54)
Query Neighborhood Hits	135	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	P23204	Gene names	Ppara, Nr1c1, Ppar
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

PPARD_HUMAN
NC score	0.916281 (rank : 61)	θ value	1.6813e-30 (rank : 55)
Query Neighborhood Hits	135	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q03181, Q7Z5K0, Q9BUD4	Gene names	PPARD, NR1C2, PPARB
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1) (NUCI).

NR1H2_MOUSE
NC score	0.916228 (rank : 62)	θ value	9.8567e-31 (rank : 52)
Query Neighborhood Hits	135	Target Neighborhood Hits	109	Shared Neighborhood Hits	97
SwissProt Accessions	Q60644	Gene names	Nr1h2, Lxrb, Rip15, Unr, Unr2
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Retinoid X receptor-interacting protein No.15).

PPARD_MOUSE
NC score	0.914913 (rank : 63)	θ value	1.52067e-31 (rank : 46)
Query Neighborhood Hits	135	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P35396, P37239	Gene names	Ppard, Nr1c2, Pparb
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1).

STF1_HUMAN
NC score	0.914042 (rank : 64)	θ value	1.09232e-21 (rank : 84)
Query Neighborhood Hits	135	Target Neighborhood Hits	132	Shared Neighborhood Hits	99
SwissProt Accessions	Q13285, O15196	Gene names	NR5A1, AD4BP, FTZF1, SF1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1).

PPARG_HUMAN
NC score	0.913666 (rank : 65)	θ value	9.8567e-31 (rank : 53)
Query Neighborhood Hits	135	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37231, O00684, O00710, O14515, Q15178, Q15179, Q15180, Q15832, Q86U60, Q96J12	Gene names	PPARG, NR1C3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

NR1D1_HUMAN
NC score	0.913548 (rank : 66)	θ value	1.09232e-21 (rank : 83)
Query Neighborhood Hits	135	Target Neighborhood Hits	140	Shared Neighborhood Hits	95
SwissProt Accessions	P20393, Q15304	Gene names	NR1D1, EAR1, HREV, THRAL
Domain Architecture
Description	Orphan nuclear receptor NR1D1 (V-erbA-related protein EAR-1) (Rev- erbA-alpha).

PPARG_MOUSE
NC score	0.913299 (rank : 67)	θ value	7.54701e-31 (rank : 51)
Query Neighborhood Hits	135	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37238	Gene names	Pparg, Nr1c3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

THA_MOUSE
NC score	0.911244 (rank : 68)	θ value	2.96777e-27 (rank : 60)
Query Neighborhood Hits	135	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	P63058, P10685, P15827, P16416, P37241, Q63107, Q63195, Q63196, Q99146	Gene names	Thra, C-erba-alpha, Nr1a1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1).

THA_HUMAN
NC score	0.911241 (rank : 69)	θ value	2.96777e-27 (rank : 59)
Query Neighborhood Hits	135	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	P10827, P21205, Q8N6A1, Q96H73	Gene names	THRA, ERBA1, NR1A1, THRA1
Domain Architecture
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1) (EAR-7) (EAR7).

NR1H2_HUMAN
NC score	0.908055 (rank : 70)	θ value	1.24688e-25 (rank : 68)
Query Neighborhood Hits	135	Target Neighborhood Hits	114	Shared Neighborhood Hits	96
SwissProt Accessions	P55055, Q12970	Gene names	NR1H2, LXRB, NER, UNR
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Nuclear receptor NER).

NR1D2_HUMAN
NC score	0.906845 (rank : 71)	θ value	2.87452e-22 (rank : 80)
Query Neighborhood Hits	135	Target Neighborhood Hits	115	Shared Neighborhood Hits	94
SwissProt Accessions	Q14995, O00402, Q86XD4	Gene names	NR1D2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (EAR-1R) (Orphan nuclear hormone receptor BD73).

THB2_HUMAN
NC score	0.905807 (rank : 72)	θ value	5.59698e-26 (rank : 65)
Query Neighborhood Hits	135	Target Neighborhood Hits	104	Shared Neighborhood Hits	98
SwissProt Accessions	P37243	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor beta-2.

THB1_HUMAN
NC score	0.905371 (rank : 73)	θ value	5.59698e-26 (rank : 64)
Query Neighborhood Hits	135	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P10828, Q13986	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture
Description	Thyroid hormone receptor beta-1.

NR1D2_MOUSE
NC score	0.904614 (rank : 74)	θ value	4.43474e-23 (rank : 79)
Query Neighborhood Hits	135	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	Q60674, Q60646	Gene names	Nr1d2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (Orphan nuclear receptor RVR).

THB1_MOUSE
NC score	0.904015 (rank : 75)	θ value	3.62785e-25 (rank : 72)
Query Neighborhood Hits	135	Target Neighborhood Hits	105	Shared Neighborhood Hits	98
SwissProt Accessions	P37242	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-1.

THB2_MOUSE
NC score	0.903886 (rank : 76)	θ value	3.62785e-25 (rank : 73)
Query Neighborhood Hits	135	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P37244	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-2.

RORG_MOUSE
NC score	0.903516 (rank : 77)	θ value	1.24688e-25 (rank : 69)
Query Neighborhood Hits	135	Target Neighborhood Hits	107	Shared Neighborhood Hits	94
SwissProt Accessions	P51450, Q61027, Q91YT5, Q9QXD9, Q9R177	Gene names	Rorc, Nr1f3, Rorg, Thor
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma) (Thymus orphan receptor) (TOR).

RORB_HUMAN
NC score	0.900846 (rank : 78)	θ value	1.62847e-25 (rank : 70)
Query Neighborhood Hits	135	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	Q92753, Q8WX73	Gene names	RORB, NR1F2, RZRB
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORB_MOUSE
NC score	0.900641 (rank : 79)	θ value	1.62847e-25 (rank : 71)
Query Neighborhood Hits	135	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	Q8R1B8	Gene names	Rorb, Nr1f2
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORG_HUMAN
NC score	0.900192 (rank : 80)	θ value	7.30988e-26 (rank : 66)
Query Neighborhood Hits	135	Target Neighborhood Hits	119	Shared Neighborhood Hits	97
SwissProt Accessions	P51449, Q8N5V7, Q8NCY8	Gene names	RORC, NR1F3, RORG, RZRG
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma).

RORA_HUMAN
NC score	0.899456 (rank : 81)	θ value	8.08199e-25 (rank : 74)
Query Neighborhood Hits	135	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P35398, P35397, P35399, P45445, Q96H83	Gene names	RORA, NR1F1, RZRA
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

RORA_MOUSE
NC score	0.899381 (rank : 82)	θ value	9.54697e-26 (rank : 67)
Query Neighborhood Hits	135	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P51448, P70283, P97741, P97773, Q923G1	Gene names	Rora, Nr1f1, Rzra
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

VDR_MOUSE
NC score	0.898703 (rank : 83)	θ value	2.7842e-17 (rank : 94)
Query Neighborhood Hits	135	Target Neighborhood Hits	103	Shared Neighborhood Hits	96
SwissProt Accessions	P48281	Gene names	Vdr, Nr1i1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

VDR_HUMAN
NC score	0.897157 (rank : 84)	θ value	2.7842e-17 (rank : 93)
Query Neighborhood Hits	135	Target Neighborhood Hits	112	Shared Neighborhood Hits	96
SwissProt Accessions	P11473	Gene names	VDR, NR1I1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

PXR_MOUSE
NC score	0.896035 (rank : 85)	θ value	3.07829e-16 (rank : 95)
Query Neighborhood Hits	135	Target Neighborhood Hits	107	Shared Neighborhood Hits	97
SwissProt Accessions	O54915	Gene names	Nr1i2, Pxr
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor).

PXR_HUMAN
NC score	0.893920 (rank : 86)	θ value	4.02038e-16 (rank : 96)
Query Neighborhood Hits	135	Target Neighborhood Hits	107	Shared Neighborhood Hits	97
SwissProt Accessions	O75469, Q96AC7, Q9UJ22, Q9UJ23, Q9UJ24, Q9UJ25, Q9UJ26, Q9UJ27	Gene names	NR1I2, PXR
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor) (Orphan nuclear receptor PAR1) (Steroid and xenobiotic receptor) (SXR).

GCR_HUMAN
NC score	0.881981 (rank : 87)	θ value	4.43474e-23 (rank : 78)
Query Neighborhood Hits	135	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P04150, P04151, Q53EP5, Q6N0A4	Gene names	NR3C1, GRL
Domain Architecture
Description	Glucocorticoid receptor (GR).

ANDR_MOUSE
NC score	0.879705 (rank : 88)	θ value	8.93572e-24 (rank : 77)
Query Neighborhood Hits	135	Target Neighborhood Hits	133	Shared Neighborhood Hits	94
SwissProt Accessions	P19091	Gene names	Ar, Nr3c4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

ANDR_HUMAN
NC score	0.878356 (rank : 89)	θ value	1.80048e-24 (rank : 76)
Query Neighborhood Hits	135	Target Neighborhood Hits	126	Shared Neighborhood Hits	94
SwissProt Accessions	P10275	Gene names	AR, DHTR, NR3C4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

GCR_MOUSE
NC score	0.874941 (rank : 90)	θ value	3.17815e-21 (rank : 89)
Query Neighborhood Hits	135	Target Neighborhood Hits	117	Shared Neighborhood Hits	94
SwissProt Accessions	P06537, Q61628, Q61629	Gene names	Nr3c1, Grl, Grl1
Domain Architecture
Description	Glucocorticoid receptor (GR).

MCR_HUMAN
NC score	0.873100 (rank : 91)	θ value	1.09232e-21 (rank : 82)
Query Neighborhood Hits	135	Target Neighborhood Hits	149	Shared Neighborhood Hits	95
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

PRGR_HUMAN
NC score	0.870988 (rank : 92)	θ value	2.43343e-21 (rank : 88)
Query Neighborhood Hits	135	Target Neighborhood Hits	163	Shared Neighborhood Hits	98
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

MCR_MOUSE
NC score	0.869192 (rank : 93)	θ value	8.36355e-22 (rank : 81)
Query Neighborhood Hits	135	Target Neighborhood Hits	162	Shared Neighborhood Hits	94
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

PRGR_MOUSE
NC score	0.865277 (rank : 94)	θ value	7.0802e-21 (rank : 90)
Query Neighborhood Hits	135	Target Neighborhood Hits	286	Shared Neighborhood Hits	103
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

SHP_HUMAN
NC score	0.646053 (rank : 95)	θ value	1.74391e-19 (rank : 91)
Query Neighborhood Hits	135	Target Neighborhood Hits	57	Shared Neighborhood Hits	56
SwissProt Accessions	Q15466, Q5QP36	Gene names	NR0B2, SHP
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

SHP_MOUSE
NC score	0.638957 (rank : 96)	θ value	1.24977e-17 (rank : 92)
Query Neighborhood Hits	135	Target Neighborhood Hits	53	Shared Neighborhood Hits	53
SwissProt Accessions	Q62227, Q53Z53	Gene names	Nr0b2, Shp
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

DAX1_MOUSE
NC score	0.612513 (rank : 97)	θ value	9.26847e-13 (rank : 98)
Query Neighborhood Hits	135	Target Neighborhood Hits	70	Shared Neighborhood Hits	60
SwissProt Accessions	Q61066, O09068, O09147	Gene names	Nr0b1, Ahch, Dax1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1).

DAX1_HUMAN
NC score	0.594189 (rank : 98)	θ value	1.68911e-14 (rank : 97)
Query Neighborhood Hits	135	Target Neighborhood Hits	65	Shared Neighborhood Hits	59
SwissProt Accessions	P51843, Q96F69	Gene names	NR0B1, AHC, DAX1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1) (DSS-AHC critical region on the X chromosome protein 1).

CO5A2_HUMAN
NC score	0.023985 (rank : 99)	θ value	0.0736092 (rank : 99)
Query Neighborhood Hits	135	Target Neighborhood Hits	760	Shared Neighborhood Hits	33
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CO9A1_MOUSE
NC score	0.022381 (rank : 100)	θ value	1.38821 (rank : 107)
Query Neighborhood Hits	135	Target Neighborhood Hits	477	Shared Neighborhood Hits	30
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO9A2_HUMAN
NC score	0.020793 (rank : 101)	θ value	1.06291 (rank : 105)
Query Neighborhood Hits	135	Target Neighborhood Hits	261	Shared Neighborhood Hits	24
SwissProt Accessions	Q14055	Gene names	COL9A2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

CO4A2_HUMAN
NC score	0.020684 (rank : 102)	θ value	0.365318 (rank : 101)
Query Neighborhood Hits	135	Target Neighborhood Hits	454	Shared Neighborhood Hits	27
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CO2A1_HUMAN
NC score	0.019397 (rank : 103)	θ value	1.81305 (rank : 108)
Query Neighborhood Hits	135	Target Neighborhood Hits	486	Shared Neighborhood Hits	29
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO2A1_MOUSE
NC score	0.018698 (rank : 104)	θ value	1.81305 (rank : 109)
Query Neighborhood Hits	135	Target Neighborhood Hits	483	Shared Neighborhood Hits	27
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO5A3_HUMAN
NC score	0.018610 (rank : 105)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	135	Target Neighborhood Hits	433	Shared Neighborhood Hits	29
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

CO4A1_HUMAN
NC score	0.018348 (rank : 106)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	135	Target Neighborhood Hits	425	Shared Neighborhood Hits	26
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CO4A2_MOUSE
NC score	0.017602 (rank : 107)	θ value	0.813845 (rank : 104)
Query Neighborhood Hits	135	Target Neighborhood Hits	492	Shared Neighborhood Hits	27
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

COJA1_HUMAN
NC score	0.016617 (rank : 108)	θ value	4.03905 (rank : 120)
Query Neighborhood Hits	135	Target Neighborhood Hits	323	Shared Neighborhood Hits	26
SwissProt Accessions	Q14993, Q00559, Q05850, Q12885, Q13676, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2	Gene names	COL19A1
Domain Architecture
Description	Collagen alpha-1(XIX) chain precursor (Collagen alpha-1(Y) chain).

CO9A1_HUMAN
NC score	0.015800 (rank : 109)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	135	Target Neighborhood Hits	420	Shared Neighborhood Hits	30
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CEND_HUMAN
NC score	0.015161 (rank : 110)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	135	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N111, Q9NYM6	Gene names	CEND1, BM88
Domain Architecture	No domain graphic available
Description	Cell cycle exit and neuronal differentiation protein 1 (BM88 antigen).

MBB1A_HUMAN
NC score	0.014508 (rank : 111)	θ value	0.365318 (rank : 102)
Query Neighborhood Hits	135	Target Neighborhood Hits	665	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

COBA2_MOUSE
NC score	0.012347 (rank : 112)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	135	Target Neighborhood Hits	501	Shared Neighborhood Hits	28
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

COIA1_MOUSE
NC score	0.011129 (rank : 113)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	135	Target Neighborhood Hits	481	Shared Neighborhood Hits	25
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

RIN3_HUMAN
NC score	0.010135 (rank : 114)	θ value	2.36792 (rank : 112)
Query Neighborhood Hits	135	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

OGFR_HUMAN
NC score	0.009847 (rank : 115)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	135	Target Neighborhood Hits	1582	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

CO7A1_HUMAN
NC score	0.009704 (rank : 116)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	135	Target Neighborhood Hits	807	Shared Neighborhood Hits	28
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

MTSS1_HUMAN
NC score	0.007623 (rank : 117)	θ value	4.03905 (rank : 121)
Query Neighborhood Hits	135	Target Neighborhood Hits	504	Shared Neighborhood Hits	17
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

CLAP2_MOUSE
NC score	0.006434 (rank : 118)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	135	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BRT1, Q8CHE3, Q99JI3, Q9DB80	Gene names	Clasp2, Kiaa0627
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2).

OXRP_HUMAN
NC score	0.006340 (rank : 119)	θ value	3.0926 (rank : 115)
Query Neighborhood Hits	135	Target Neighborhood Hits	544	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

RAI1_MOUSE
NC score	0.005612 (rank : 120)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	135	Target Neighborhood Hits	344	Shared Neighborhood Hits	9
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

CJ064_HUMAN
NC score	0.005530 (rank : 121)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	135	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZS81, Q8N4A3	Gene names	C10orf64
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf64.

SON_MOUSE
NC score	0.004601 (rank : 122)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	135	Target Neighborhood Hits	957	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

CSKI1_HUMAN
NC score	0.004378 (rank : 123)	θ value	0.62314 (rank : 103)
Query Neighborhood Hits	135	Target Neighborhood Hits	997	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

IRS2_MOUSE
NC score	0.004216 (rank : 124)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	135	Target Neighborhood Hits	248	Shared Neighborhood Hits	12
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

PARD3_HUMAN
NC score	0.003924 (rank : 125)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	135	Target Neighborhood Hits	312	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

FOXJ3_MOUSE
NC score	0.003451 (rank : 126)	θ value	2.36792 (rank : 110)
Query Neighborhood Hits	135	Target Neighborhood Hits	190	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BUR3, Q3UTD8	Gene names	Foxj3, Kiaa1041
Domain Architecture
Description	Forkhead box protein J3.

FOXJ3_HUMAN
NC score	0.003196 (rank : 127)	θ value	3.0926 (rank : 114)
Query Neighborhood Hits	135	Target Neighborhood Hits	177	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPW0, Q9NSS7	Gene names	FOXJ3, KIAA1041
Domain Architecture
Description	Forkhead box protein J3.

YAP1_HUMAN
NC score	0.002605 (rank : 128)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	135	Target Neighborhood Hits	173	Shared Neighborhood Hits	5
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

PCLO_MOUSE
NC score	0.000471 (rank : 129)	θ value	2.36792 (rank : 111)
Query Neighborhood Hits	135	Target Neighborhood Hits	2275	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

CSKI2_MOUSE
NC score	-0.000667 (rank : 130)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	135	Target Neighborhood Hits	812	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ZN687_HUMAN
NC score	-0.000713 (rank : 131)	θ value	3.0926 (rank : 116)
Query Neighborhood Hits	135	Target Neighborhood Hits	1244	Shared Neighborhood Hits	29
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

ZN516_MOUSE
NC score	-0.003391 (rank : 132)	θ value	2.36792 (rank : 113)
Query Neighborhood Hits	135	Target Neighborhood Hits	1197	Shared Neighborhood Hits	29
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

ZN341_HUMAN
NC score	-0.003922 (rank : 133)	θ value	0.163984 (rank : 100)
Query Neighborhood Hits	135	Target Neighborhood Hits	803	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BYN7, Q5JXM8, Q96ST5	Gene names	ZNF341
Domain Architecture	No domain graphic available
Description	Zinc finger protein 341.

ZFP28_HUMAN
NC score	-0.006689 (rank : 134)	θ value	1.06291 (rank : 106)
Query Neighborhood Hits	135	Target Neighborhood Hits	843	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NHY6, Q9BY30, Q9P2B6	Gene names	ZFP28, KIAA1431
Domain Architecture
Description	Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6).

PKN3_MOUSE
NC score	-0.008378 (rank : 135)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	135	Target Neighborhood Hits	1009	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).