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Network neighborhood for query Sequence : YAP1_HUMAN

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YAP1_HUMAN
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

YAP1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	173	Target Neighborhood Hits	173	Shared Neighborhood Hits	173
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

YAP1_MOUSE
θ value	0 (rank : 2)	NC score	0.936833 (rank : 2)
Query Neighborhood Hits	173	Target Neighborhood Hits	96	Shared Neighborhood Hits	72
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

WWTR1_MOUSE
θ value	4.36332e-79 (rank : 3)	NC score	0.922775 (rank : 4)
Query Neighborhood Hits	173	Target Neighborhood Hits	54	Shared Neighborhood Hits	41
SwissProt Accessions	Q9EPK5, Q99KI4	Gene names	Wwtr1, Taz
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

WWTR1_HUMAN
θ value	5.69867e-79 (rank : 4)	NC score	0.923719 (rank : 3)
Query Neighborhood Hits	173	Target Neighborhood Hits	76	Shared Neighborhood Hits	49
SwissProt Accessions	Q9GZV5, Q8N3P2, Q9Y3W6	Gene names	WWTR1, TAZ
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

SMUF1_HUMAN
θ value	3.77169e-06 (rank : 5)	NC score	0.349274 (rank : 21)
Query Neighborhood Hits	173	Target Neighborhood Hits	135	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

MAGI1_HUMAN
θ value	6.43352e-06 (rank : 6)	NC score	0.308069 (rank : 31)
Query Neighborhood Hits	173	Target Neighborhood Hits	388	Shared Neighborhood Hits	54
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

MAGI1_MOUSE
θ value	6.43352e-06 (rank : 7)	NC score	0.309695 (rank : 29)
Query Neighborhood Hits	173	Target Neighborhood Hits	403	Shared Neighborhood Hits	54
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

WWP1_MOUSE
θ value	8.40245e-06 (rank : 8)	NC score	0.384374 (rank : 9)
Query Neighborhood Hits	173	Target Neighborhood Hits	138	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

MAGI2_MOUSE
θ value	1.09739e-05 (rank : 9)	NC score	0.328476 (rank : 26)
Query Neighborhood Hits	173	Target Neighborhood Hits	370	Shared Neighborhood Hits	66
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

NED4L_MOUSE
θ value	1.09739e-05 (rank : 10)	NC score	0.351226 (rank : 18)
Query Neighborhood Hits	173	Target Neighborhood Hits	231	Shared Neighborhood Hits	55
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

MAGI2_HUMAN
θ value	1.87187e-05 (rank : 11)	NC score	0.319076 (rank : 27)
Query Neighborhood Hits	173	Target Neighborhood Hits	373	Shared Neighborhood Hits	58
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

NED4L_HUMAN
θ value	3.19293e-05 (rank : 12)	NC score	0.349452 (rank : 20)
Query Neighborhood Hits	173	Target Neighborhood Hits	238	Shared Neighborhood Hits	56
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

SMUF1_MOUSE
θ value	4.1701e-05 (rank : 13)	NC score	0.352506 (rank : 17)
Query Neighborhood Hits	173	Target Neighborhood Hits	142	Shared Neighborhood Hits	40
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

WWOX_HUMAN
θ value	4.1701e-05 (rank : 14)	NC score	0.345427 (rank : 23)
Query Neighborhood Hits	173	Target Neighborhood Hits	115	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NZC7, Q5MYT5, Q96KM3, Q96RF2, Q9BTT8, Q9NPC9, Q9NRF4, Q9NRF5, Q9NRF6, Q9NRK1, Q9NZC5	Gene names	WWOX, FOR, WOX1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase).

WWOX_MOUSE
θ value	4.1701e-05 (rank : 15)	NC score	0.342441 (rank : 25)
Query Neighborhood Hits	173	Target Neighborhood Hits	118	Shared Neighborhood Hits	46
SwissProt Accessions	Q91WL8, Q8C8J6, Q920Y2, Q9D2B3, Q9D339, Q9JLF5	Gene names	Wwox, Wox1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-).

ITCH_MOUSE
θ value	5.44631e-05 (rank : 16)	NC score	0.373802 (rank : 14)
Query Neighborhood Hits	173	Target Neighborhood Hits	127	Shared Neighborhood Hits	53
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

BAG3_MOUSE
θ value	7.1131e-05 (rank : 17)	NC score	0.343166 (rank : 24)
Query Neighborhood Hits	173	Target Neighborhood Hits	513	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

WWP1_HUMAN
θ value	7.1131e-05 (rank : 18)	NC score	0.377542 (rank : 12)
Query Neighborhood Hits	173	Target Neighborhood Hits	262	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

ITCH_HUMAN
θ value	9.29e-05 (rank : 19)	NC score	0.372774 (rank : 15)
Query Neighborhood Hits	173	Target Neighborhood Hits	162	Shared Neighborhood Hits	58
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

WWP2_HUMAN
θ value	9.29e-05 (rank : 20)	NC score	0.379611 (rank : 10)
Query Neighborhood Hits	173	Target Neighborhood Hits	177	Shared Neighborhood Hits	62
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

WWP2_MOUSE
θ value	9.29e-05 (rank : 21)	NC score	0.378511 (rank : 11)
Query Neighborhood Hits	173	Target Neighborhood Hits	118	Shared Neighborhood Hits	52
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

STXB4_HUMAN
θ value	0.000158464 (rank : 22)	NC score	0.235143 (rank : 35)
Query Neighborhood Hits	173	Target Neighborhood Hits	616	Shared Neighborhood Hits	47
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

WWC1_HUMAN
θ value	0.000158464 (rank : 23)	NC score	0.395532 (rank : 7)
Query Neighborhood Hits	173	Target Neighborhood Hits	290	Shared Neighborhood Hits	43
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

NEDD4_HUMAN
θ value	0.00020696 (rank : 24)	NC score	0.350602 (rank : 19)
Query Neighborhood Hits	173	Target Neighborhood Hits	214	Shared Neighborhood Hits	51
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

STXB4_MOUSE
θ value	0.00020696 (rank : 25)	NC score	0.238853 (rank : 33)
Query Neighborhood Hits	173	Target Neighborhood Hits	629	Shared Neighborhood Hits	47
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

WWC1_MOUSE
θ value	0.000270298 (rank : 26)	NC score	0.390157 (rank : 8)
Query Neighborhood Hits	173	Target Neighborhood Hits	290	Shared Neighborhood Hits	36
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

SMUF2_HUMAN
θ value	0.00035302 (rank : 27)	NC score	0.360270 (rank : 16)
Query Neighborhood Hits	173	Target Neighborhood Hits	142	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

NEDD4_MOUSE
θ value	0.000461057 (rank : 28)	NC score	0.346506 (rank : 22)
Query Neighborhood Hits	173	Target Neighborhood Hits	212	Shared Neighborhood Hits	54
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

BAG3_HUMAN
θ value	0.000602161 (rank : 29)	NC score	0.375350 (rank : 13)
Query Neighborhood Hits	173	Target Neighborhood Hits	314	Shared Neighborhood Hits	72
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

SGIP1_MOUSE
θ value	0.00298849 (rank : 30)	NC score	0.107991 (rank : 62)
Query Neighborhood Hits	173	Target Neighborhood Hits	180	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SAV1_HUMAN
θ value	0.00509761 (rank : 31)	NC score	0.448007 (rank : 5)
Query Neighborhood Hits	173	Target Neighborhood Hits	51	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

SAV1_MOUSE
θ value	0.00509761 (rank : 32)	NC score	0.446855 (rank : 6)
Query Neighborhood Hits	173	Target Neighborhood Hits	48	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VEB2, Q9D9N9, Q9ER46	Gene names	Sav1, Ww45, Wwp3
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (mWW45).

PKHA5_HUMAN
θ value	0.0193708 (rank : 33)	NC score	0.237511 (rank : 34)
Query Neighborhood Hits	173	Target Neighborhood Hits	455	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

APBB1_HUMAN
θ value	0.0330416 (rank : 34)	NC score	0.099189 (rank : 64)
Query Neighborhood Hits	173	Target Neighborhood Hits	62	Shared Neighborhood Hits	20
SwissProt Accessions	O00213, Q96A93	Gene names	APBB1, FE65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

APBB1_MOUSE
θ value	0.0330416 (rank : 35)	NC score	0.098023 (rank : 65)
Query Neighborhood Hits	173	Target Neighborhood Hits	75	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QXJ1, O08642, Q3TPU0, Q8BNF4, Q8BSR9	Gene names	Apbb1, Fe65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

DRP2_HUMAN
θ value	0.0330416 (rank : 36)	NC score	0.130469 (rank : 53)
Query Neighborhood Hits	173	Target Neighborhood Hits	186	Shared Neighborhood Hits	25
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

PRP40_HUMAN
θ value	0.0330416 (rank : 37)	NC score	0.155614 (rank : 49)
Query Neighborhood Hits	173	Target Neighborhood Hits	442	Shared Neighborhood Hits	45
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

MDC1_HUMAN
θ value	0.0431538 (rank : 38)	NC score	0.089332 (rank : 68)
Query Neighborhood Hits	173	Target Neighborhood Hits	1446	Shared Neighborhood Hits	79
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

RGS3_MOUSE
θ value	0.0431538 (rank : 39)	NC score	0.072596 (rank : 77)
Query Neighborhood Hits	173	Target Neighborhood Hits	1621	Shared Neighborhood Hits	94
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

INP5E_HUMAN
θ value	0.0736092 (rank : 40)	NC score	0.060795 (rank : 95)
Query Neighborhood Hits	173	Target Neighborhood Hits	201	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

MDC1_MOUSE
θ value	0.0736092 (rank : 41)	NC score	0.083280 (rank : 70)
Query Neighborhood Hits	173	Target Neighborhood Hits	998	Shared Neighborhood Hits	68
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

NDUB5_MOUSE
θ value	0.0736092 (rank : 42)	NC score	0.067957 (rank : 80)
Query Neighborhood Hits	173	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CQH3	Gene names	Ndufb5
Domain Architecture	No domain graphic available
Description	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial precursor (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase SGDH subunit) (Complex I-SGDH) (CI-SGDH).

SETD2_HUMAN
θ value	0.0736092 (rank : 43)	NC score	0.118953 (rank : 58)
Query Neighborhood Hits	173	Target Neighborhood Hits	412	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

ASPP1_HUMAN
θ value	0.0961366 (rank : 44)	NC score	0.041195 (rank : 131)
Query Neighborhood Hits	173	Target Neighborhood Hits	956	Shared Neighborhood Hits	35
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

RHG12_MOUSE
θ value	0.125558 (rank : 45)	NC score	0.105374 (rank : 63)
Query Neighborhood Hits	173	Target Neighborhood Hits	204	Shared Neighborhood Hits	34
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

SAPS1_HUMAN
θ value	0.125558 (rank : 46)	NC score	0.053881 (rank : 107)
Query Neighborhood Hits	173	Target Neighborhood Hits	704	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

CCP2_MOUSE
θ value	0.163984 (rank : 47)	NC score	0.036963 (rank : 136)
Query Neighborhood Hits	173	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JHG2	Gene names	Dscr1l1
Domain Architecture
Description	Calcipressin-2 (Down syndrome candidate region 1-like protein 1) (Myocyte-enriched calcineurin-interacting protein 2) (MCIP2).

PIN1_HUMAN
θ value	0.163984 (rank : 48)	NC score	0.297867 (rank : 32)
Query Neighborhood Hits	173	Target Neighborhood Hits	59	Shared Neighborhood Hits	40
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

PIN1_MOUSE
θ value	0.163984 (rank : 49)	NC score	0.309536 (rank : 30)
Query Neighborhood Hits	173	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

UTRO_HUMAN
θ value	0.163984 (rank : 50)	NC score	0.059702 (rank : 97)
Query Neighborhood Hits	173	Target Neighborhood Hits	960	Shared Neighborhood Hits	40
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

BSN_MOUSE
θ value	0.21417 (rank : 51)	NC score	0.063861 (rank : 89)
Query Neighborhood Hits	173	Target Neighborhood Hits	2057	Shared Neighborhood Hits	92
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

DMD_HUMAN
θ value	0.21417 (rank : 52)	NC score	0.064565 (rank : 88)
Query Neighborhood Hits	173	Target Neighborhood Hits	1135	Shared Neighborhood Hits	38
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

DMD_MOUSE
θ value	0.21417 (rank : 53)	NC score	0.061143 (rank : 93)
Query Neighborhood Hits	173	Target Neighborhood Hits	1111	Shared Neighborhood Hits	38
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

RGS3_HUMAN
θ value	0.21417 (rank : 54)	NC score	0.066006 (rank : 86)
Query Neighborhood Hits	173	Target Neighborhood Hits	1375	Shared Neighborhood Hits	76
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RHG12_HUMAN
θ value	0.21417 (rank : 55)	NC score	0.094919 (rank : 66)
Query Neighborhood Hits	173	Target Neighborhood Hits	190	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

BIM_MOUSE
θ value	0.279714 (rank : 56)	NC score	0.051865 (rank : 110)
Query Neighborhood Hits	173	Target Neighborhood Hits	124	Shared Neighborhood Hits	10
SwissProt Accessions	O54918, O54919, O54920	Gene names	Bcl2l11, Bim
Domain Architecture
Description	Bcl-2-like protein 11 (Bcl2-interacting mediator of cell death).

GAS7_HUMAN
θ value	0.279714 (rank : 57)	NC score	0.212241 (rank : 37)
Query Neighborhood Hits	173	Target Neighborhood Hits	258	Shared Neighborhood Hits	43
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

PI5PA_HUMAN
θ value	0.279714 (rank : 58)	NC score	0.074433 (rank : 76)
Query Neighborhood Hits	173	Target Neighborhood Hits	749	Shared Neighborhood Hits	62
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PRP40_MOUSE
θ value	0.279714 (rank : 59)	NC score	0.148059 (rank : 50)
Query Neighborhood Hits	173	Target Neighborhood Hits	447	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

ASPP1_MOUSE
θ value	0.365318 (rank : 60)	NC score	0.043982 (rank : 127)
Query Neighborhood Hits	173	Target Neighborhood Hits	1244	Shared Neighborhood Hits	57
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

NACAM_MOUSE
θ value	0.365318 (rank : 61)	NC score	0.066845 (rank : 84)
Query Neighborhood Hits	173	Target Neighborhood Hits	1866	Shared Neighborhood Hits	97
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

GAS7_MOUSE
θ value	0.62314 (rank : 62)	NC score	0.222229 (rank : 36)
Query Neighborhood Hits	173	Target Neighborhood Hits	259	Shared Neighborhood Hits	42
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

MAML1_MOUSE
θ value	0.62314 (rank : 63)	NC score	0.039671 (rank : 132)
Query Neighborhood Hits	173	Target Neighborhood Hits	279	Shared Neighborhood Hits	29
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

MINT_HUMAN
θ value	0.62314 (rank : 64)	NC score	0.047163 (rank : 120)
Query Neighborhood Hits	173	Target Neighborhood Hits	1291	Shared Neighborhood Hits	71
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PI5PA_MOUSE
θ value	0.62314 (rank : 65)	NC score	0.066253 (rank : 85)
Query Neighborhood Hits	173	Target Neighborhood Hits	331	Shared Neighborhood Hits	44
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PINL_HUMAN
θ value	0.62314 (rank : 66)	NC score	0.316863 (rank : 28)
Query Neighborhood Hits	173	Target Neighborhood Hits	47	Shared Neighborhood Hits	40
SwissProt Accessions	O15428	Gene names	PIN1L
Domain Architecture
Description	PIN1-like protein.

WHRN_MOUSE
θ value	0.62314 (rank : 67)	NC score	0.058615 (rank : 99)
Query Neighborhood Hits	173	Target Neighborhood Hits	412	Shared Neighborhood Hits	24
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

WNK2_HUMAN
θ value	0.62314 (rank : 68)	NC score	0.017989 (rank : 179)
Query Neighborhood Hits	173	Target Neighborhood Hits	1407	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ZEP2_HUMAN
θ value	0.62314 (rank : 69)	NC score	0.019033 (rank : 175)
Query Neighborhood Hits	173	Target Neighborhood Hits	937	Shared Neighborhood Hits	26
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

ANC1_MOUSE
θ value	0.813845 (rank : 70)	NC score	0.050745 (rank : 115)
Query Neighborhood Hits	173	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	P53995, Q8BP33, Q8C772	Gene names	Anapc1, Mcpr, Tsg24
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Protein Tsg24) (Mitotic checkpoint regulator).

CK024_MOUSE
θ value	0.813845 (rank : 71)	NC score	0.062572 (rank : 90)
Query Neighborhood Hits	173	Target Neighborhood Hits	307	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

OGFR_HUMAN
θ value	0.813845 (rank : 72)	NC score	0.059235 (rank : 98)
Query Neighborhood Hits	173	Target Neighborhood Hits	1582	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

GRIN1_MOUSE
θ value	1.06291 (rank : 73)	NC score	0.058151 (rank : 101)
Query Neighborhood Hits	173	Target Neighborhood Hits	337	Shared Neighborhood Hits	37
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

HGS_MOUSE
θ value	1.06291 (rank : 74)	NC score	0.032351 (rank : 144)
Query Neighborhood Hits	173	Target Neighborhood Hits	589	Shared Neighborhood Hits	40
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

LAD1_MOUSE
θ value	1.06291 (rank : 75)	NC score	0.051408 (rank : 111)
Query Neighborhood Hits	173	Target Neighborhood Hits	391	Shared Neighborhood Hits	33
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

MUC5B_HUMAN
θ value	1.06291 (rank : 76)	NC score	0.037600 (rank : 135)
Query Neighborhood Hits	173	Target Neighborhood Hits	1020	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

PAX1_MOUSE
θ value	1.06291 (rank : 77)	NC score	0.030202 (rank : 148)
Query Neighborhood Hits	173	Target Neighborhood Hits	69	Shared Neighborhood Hits	10
SwissProt Accessions	P09084, Q9R2B1	Gene names	Pax1, Pax-1
Domain Architecture
Description	Paired box protein Pax-1.

SYNPO_HUMAN
θ value	1.06291 (rank : 78)	NC score	0.046039 (rank : 124)
Query Neighborhood Hits	173	Target Neighborhood Hits	281	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TTBK1_HUMAN
θ value	1.06291 (rank : 79)	NC score	0.020516 (rank : 170)
Query Neighborhood Hits	173	Target Neighborhood Hits	1058	Shared Neighborhood Hits	47
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

MRCKG_HUMAN
θ value	1.38821 (rank : 80)	NC score	0.006344 (rank : 201)
Query Neighborhood Hits	173	Target Neighborhood Hits	1519	Shared Neighborhood Hits	28
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

RP1L1_HUMAN
θ value	1.38821 (rank : 81)	NC score	0.035067 (rank : 142)
Query Neighborhood Hits	173	Target Neighborhood Hits	1072	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

HN1L_MOUSE
θ value	1.81305 (rank : 82)	NC score	0.031929 (rank : 145)
Query Neighborhood Hits	173	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PGH2	Gene names	D17Ertd441e
Domain Architecture	No domain graphic available
Description	Hematological and neurological expressed 1-like protein (HN1-like protein).

RC3H1_HUMAN
θ value	1.81305 (rank : 83)	NC score	0.023600 (rank : 164)
Query Neighborhood Hits	173	Target Neighborhood Hits	433	Shared Neighborhood Hits	28
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RHG09_HUMAN
θ value	1.81305 (rank : 84)	NC score	0.039321 (rank : 134)
Query Neighborhood Hits	173	Target Neighborhood Hits	186	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

SPEG_HUMAN
θ value	1.81305 (rank : 85)	NC score	0.011429 (rank : 194)
Query Neighborhood Hits	173	Target Neighborhood Hits	1762	Shared Neighborhood Hits	56
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ANC1_HUMAN
θ value	2.36792 (rank : 86)	NC score	0.046964 (rank : 121)
Query Neighborhood Hits	173	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H1A4, Q9BSE6, Q9H8D0	Gene names	ANAPC1, TSG24
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Protein Tsg24) (Mitotic checkpoint regulator).

CN152_HUMAN
θ value	2.36792 (rank : 87)	NC score	0.056437 (rank : 103)
Query Neighborhood Hits	173	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N9Y4, Q96GY1	Gene names	C14orf152
Domain Architecture	No domain graphic available
Description	Protein C14orf152.

COA2_HUMAN
θ value	2.36792 (rank : 88)	NC score	0.026035 (rank : 158)
Query Neighborhood Hits	173	Target Neighborhood Hits	184	Shared Neighborhood Hits	23
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

MTSS1_MOUSE
θ value	2.36792 (rank : 89)	NC score	0.030629 (rank : 146)
Query Neighborhood Hits	173	Target Neighborhood Hits	592	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

MYST4_HUMAN
θ value	2.36792 (rank : 90)	NC score	0.016106 (rank : 185)
Query Neighborhood Hits	173	Target Neighborhood Hits	671	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

TTC15_MOUSE
θ value	2.36792 (rank : 91)	NC score	0.028675 (rank : 151)
Query Neighborhood Hits	173	Target Neighborhood Hits	113	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K2L8, Q8BX27	Gene names	Ttc15
Domain Architecture
Description	Tetratricopeptide repeat protein 15 (TPR repeat protein 15).

ARI1B_HUMAN
θ value	3.0926 (rank : 92)	NC score	0.043914 (rank : 128)
Query Neighborhood Hits	173	Target Neighborhood Hits	567	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

CEL_HUMAN
θ value	3.0926 (rank : 93)	NC score	0.030572 (rank : 147)
Query Neighborhood Hits	173	Target Neighborhood Hits	896	Shared Neighborhood Hits	56
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

EP400_MOUSE
θ value	3.0926 (rank : 94)	NC score	0.026786 (rank : 155)
Query Neighborhood Hits	173	Target Neighborhood Hits	592	Shared Neighborhood Hits	55
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

EPC1_HUMAN
θ value	3.0926 (rank : 95)	NC score	0.017891 (rank : 180)
Query Neighborhood Hits	173	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H2F5, Q5VW54, Q5VW56, Q5VW58, Q8NAQ4, Q8NE21, Q96LF4, Q96RR6, Q9H7T7	Gene names	EPC1
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 1.

K1802_MOUSE
θ value	3.0926 (rank : 96)	NC score	0.036435 (rank : 137)
Query Neighborhood Hits	173	Target Neighborhood Hits	1596	Shared Neighborhood Hits	75
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

KLF11_HUMAN
θ value	3.0926 (rank : 97)	NC score	0.002931 (rank : 206)
Query Neighborhood Hits	173	Target Neighborhood Hits	717	Shared Neighborhood Hits	9
SwissProt Accessions	O14901	Gene names	KLF11, FKLF, TIEG2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 11 (Transforming growth factor-beta-inducible early growth response protein 2) (TGFB-inducible early growth response protein 2) (TIEG-2).

KLF11_MOUSE
θ value	3.0926 (rank : 98)	NC score	0.003035 (rank : 205)
Query Neighborhood Hits	173	Target Neighborhood Hits	714	Shared Neighborhood Hits	10
SwissProt Accessions	Q9EPF4	Gene names	Klf11, Tieg2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 11 (Transforming growth factor-beta-inducible early growth response protein 2) (TGFB-inducible early growth response protein 2) (TIEG-2).

NOTC2_HUMAN
θ value	3.0926 (rank : 99)	NC score	0.006326 (rank : 202)
Query Neighborhood Hits	173	Target Neighborhood Hits	1113	Shared Neighborhood Hits	38
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PCLO_MOUSE
θ value	3.0926 (rank : 100)	NC score	0.083168 (rank : 71)
Query Neighborhood Hits	173	Target Neighborhood Hits	2275	Shared Neighborhood Hits	111
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PRDM2_HUMAN
θ value	3.0926 (rank : 101)	NC score	0.014359 (rank : 190)
Query Neighborhood Hits	173	Target Neighborhood Hits	1135	Shared Neighborhood Hits	47
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

RAPH1_HUMAN
θ value	3.0926 (rank : 102)	NC score	0.046156 (rank : 123)
Query Neighborhood Hits	173	Target Neighborhood Hits	593	Shared Neighborhood Hits	56
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

WNK1_HUMAN
θ value	3.0926 (rank : 103)	NC score	0.010687 (rank : 196)
Query Neighborhood Hits	173	Target Neighborhood Hits	1158	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

BAZ2A_MOUSE
θ value	4.03905 (rank : 104)	NC score	0.035635 (rank : 140)
Query Neighborhood Hits	173	Target Neighborhood Hits	744	Shared Neighborhood Hits	55
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BSN_HUMAN
θ value	4.03905 (rank : 105)	NC score	0.061665 (rank : 92)
Query Neighborhood Hits	173	Target Neighborhood Hits	1537	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CD2L7_HUMAN
θ value	4.03905 (rank : 106)	NC score	0.008013 (rank : 199)
Query Neighborhood Hits	173	Target Neighborhood Hits	1275	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

CD2_HUMAN
θ value	4.03905 (rank : 107)	NC score	0.030028 (rank : 149)
Query Neighborhood Hits	173	Target Neighborhood Hits	504	Shared Neighborhood Hits	31
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

EVI2B_MOUSE
θ value	4.03905 (rank : 108)	NC score	0.032544 (rank : 143)
Query Neighborhood Hits	173	Target Neighborhood Hits	87	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VD58, Q3U1A3	Gene names	Evi2b
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

FILA_HUMAN
θ value	4.03905 (rank : 109)	NC score	0.029713 (rank : 150)
Query Neighborhood Hits	173	Target Neighborhood Hits	685	Shared Neighborhood Hits	30
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

FOXC1_MOUSE
θ value	4.03905 (rank : 110)	NC score	0.011260 (rank : 195)
Query Neighborhood Hits	173	Target Neighborhood Hits	218	Shared Neighborhood Hits	23
SwissProt Accessions	Q61572, O88409, Q61582	Gene names	Foxc1, Fkh1, Fkhl7, Freac3, Mf1
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3) (Transcription factor FKH-1) (Mesoderm/mesenchyme forkhead 1) (MF-1).

GSHI_HUMAN
θ value	4.03905 (rank : 111)	NC score	0.002504 (rank : 209)
Query Neighborhood Hits	173	Target Neighborhood Hits	314	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H4S2	Gene names	GSH1
Domain Architecture
Description	Homeobox protein GSH-1.

JUNB_MOUSE
θ value	4.03905 (rank : 112)	NC score	0.017418 (rank : 182)
Query Neighborhood Hits	173	Target Neighborhood Hits	116	Shared Neighborhood Hits	7
SwissProt Accessions	P09450, Q8C2G9	Gene names	Junb, Jun-b
Domain Architecture
Description	Transcription factor jun-B.

PAX1_HUMAN
θ value	4.03905 (rank : 113)	NC score	0.021560 (rank : 168)
Query Neighborhood Hits	173	Target Neighborhood Hits	72	Shared Neighborhood Hits	10
SwissProt Accessions	P15863, Q642X9, Q6NTC0, Q9Y558	Gene names	PAX1, HUP48
Domain Architecture
Description	Paired box protein Pax-1 (HUP48).

RIMB1_HUMAN
θ value	4.03905 (rank : 114)	NC score	0.019256 (rank : 174)
Query Neighborhood Hits	173	Target Neighborhood Hits	1479	Shared Neighborhood Hits	51
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SF04_MOUSE
θ value	4.03905 (rank : 115)	NC score	0.018149 (rank : 178)
Query Neighborhood Hits	173	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CH02, Q8R094	Gene names	Sf4
Domain Architecture	No domain graphic available
Description	Splicing factor 4.

SGIP1_HUMAN
θ value	4.03905 (rank : 116)	NC score	0.077651 (rank : 74)
Query Neighborhood Hits	173	Target Neighborhood Hits	198	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SPEG_MOUSE
θ value	4.03905 (rank : 117)	NC score	0.013977 (rank : 192)
Query Neighborhood Hits	173	Target Neighborhood Hits	1959	Shared Neighborhood Hits	69
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

UPK3B_HUMAN
θ value	4.03905 (rank : 118)	NC score	0.024580 (rank : 162)
Query Neighborhood Hits	173	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BT76, Q86W06	Gene names	UPK3B
Domain Architecture	No domain graphic available
Description	Uroplakin-3B precursor (Uroplakin IIIb) (UPIIIb) (p35).

YLPM1_MOUSE
θ value	4.03905 (rank : 119)	NC score	0.045698 (rank : 125)
Query Neighborhood Hits	173	Target Neighborhood Hits	505	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ANR11_HUMAN
θ value	5.27518 (rank : 120)	NC score	0.020126 (rank : 171)
Query Neighborhood Hits	173	Target Neighborhood Hits	1289	Shared Neighborhood Hits	51
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CD2AP_HUMAN
θ value	5.27518 (rank : 121)	NC score	0.014046 (rank : 191)
Query Neighborhood Hits	173	Target Neighborhood Hits	315	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

COHA1_HUMAN
θ value	5.27518 (rank : 122)	NC score	0.022630 (rank : 166)
Query Neighborhood Hits	173	Target Neighborhood Hits	400	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

EGR1_MOUSE
θ value	5.27518 (rank : 123)	NC score	0.001903 (rank : 210)
Query Neighborhood Hits	173	Target Neighborhood Hits	816	Shared Neighborhood Hits	24
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

FOXN1_HUMAN
θ value	5.27518 (rank : 124)	NC score	0.014493 (rank : 188)
Query Neighborhood Hits	173	Target Neighborhood Hits	377	Shared Neighborhood Hits	24
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

K0240_MOUSE
θ value	5.27518 (rank : 125)	NC score	0.021661 (rank : 167)
Query Neighborhood Hits	173	Target Neighborhood Hits	211	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CHH5	Gene names	Kiaa0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

KLF14_HUMAN
θ value	5.27518 (rank : 126)	NC score	0.000923 (rank : 211)
Query Neighborhood Hits	173	Target Neighborhood Hits	725	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TD94	Gene names	KLF14, BTEB5
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 14 (Transcription factor BTEB5) (Basic transcription element-binding protein 5) (BTE-binding protein 5).

MK07_MOUSE
θ value	5.27518 (rank : 127)	NC score	0.005273 (rank : 203)
Query Neighborhood Hits	173	Target Neighborhood Hits	1054	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

MUC13_MOUSE
θ value	5.27518 (rank : 128)	NC score	0.044278 (rank : 126)
Query Neighborhood Hits	173	Target Neighborhood Hits	447	Shared Neighborhood Hits	34
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

PTCD1_HUMAN
θ value	5.27518 (rank : 129)	NC score	0.019927 (rank : 172)
Query Neighborhood Hits	173	Target Neighborhood Hits	52	Shared Neighborhood Hits	12
SwissProt Accessions	O75127, Q66K60, Q9UDV2	Gene names	PTCD1, KIAA0632
Domain Architecture	No domain graphic available
Description	Pentatricopeptide repeat protein 1.

RERE_HUMAN
θ value	5.27518 (rank : 130)	NC score	0.042791 (rank : 130)
Query Neighborhood Hits	173	Target Neighborhood Hits	779	Shared Neighborhood Hits	59
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SET1A_HUMAN
θ value	5.27518 (rank : 131)	NC score	0.046727 (rank : 122)
Query Neighborhood Hits	173	Target Neighborhood Hits	690	Shared Neighborhood Hits	54
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

TMPSD_HUMAN
θ value	5.27518 (rank : 132)	NC score	0.005253 (rank : 204)
Query Neighborhood Hits	173	Target Neighborhood Hits	333	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

BAT2_MOUSE
θ value	6.88961 (rank : 133)	NC score	0.043878 (rank : 129)
Query Neighborhood Hits	173	Target Neighborhood Hits	947	Shared Neighborhood Hits	69
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CECR2_HUMAN
θ value	6.88961 (rank : 134)	NC score	0.023330 (rank : 165)
Query Neighborhood Hits	173	Target Neighborhood Hits	543	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CSPG3_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.009655 (rank : 197)
Query Neighborhood Hits	173	Target Neighborhood Hits	676	Shared Neighborhood Hits	32
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

DGCR8_HUMAN
θ value	6.88961 (rank : 136)	NC score	0.078544 (rank : 73)
Query Neighborhood Hits	173	Target Neighborhood Hits	72	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WYQ5, Q6DCB2, Q6MZE9, Q6Y2L0, Q96G39, Q96GP8, Q9H6L8, Q9H6T7, Q9NRW2	Gene names	DGCR8, C22orf12, DGCRK6
Domain Architecture
Description	DGCR8 protein (DiGeorge syndrome critical region 8).

DGCR8_MOUSE
θ value	6.88961 (rank : 137)	NC score	0.075305 (rank : 75)
Query Neighborhood Hits	173	Target Neighborhood Hits	70	Shared Neighborhood Hits	14
SwissProt Accessions	Q9EQM6	Gene names	Dgcr8
Domain Architecture	No domain graphic available
Description	DGCR8 protein (DiGeorge syndrome critical region 8 homolog) (Gy1).

MED12_HUMAN
θ value	6.88961 (rank : 138)	NC score	0.017612 (rank : 181)
Query Neighborhood Hits	173	Target Neighborhood Hits	262	Shared Neighborhood Hits	11
SwissProt Accessions	Q93074, O15410, O75557, Q9UHV6, Q9UND7	Gene names	MED12, ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230
Domain Architecture	No domain graphic available
Description	Mediator of RNA polymerase II transcription subunit 12 (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Activator-recruited cofactor 240 kDa component) (ARC240) (CAG repeat protein 45) (OPA-containing protein) (Trinucleotide repeat-containing gene 11 protein).

MUC7_HUMAN
θ value	6.88961 (rank : 139)	NC score	0.067150 (rank : 82)
Query Neighborhood Hits	173	Target Neighborhood Hits	538	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NEB2_MOUSE
θ value	6.88961 (rank : 140)	NC score	0.035400 (rank : 141)
Query Neighborhood Hits	173	Target Neighborhood Hits	889	Shared Neighborhood Hits	26
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NPBL_MOUSE
θ value	6.88961 (rank : 141)	NC score	0.035743 (rank : 138)
Query Neighborhood Hits	173	Target Neighborhood Hits	1041	Shared Neighborhood Hits	58
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PHC1_HUMAN
θ value	6.88961 (rank : 142)	NC score	0.026756 (rank : 156)
Query Neighborhood Hits	173	Target Neighborhood Hits	227	Shared Neighborhood Hits	31
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

PO6F2_MOUSE
θ value	6.88961 (rank : 143)	NC score	0.025593 (rank : 159)
Query Neighborhood Hits	173	Target Neighborhood Hits	639	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

PRGC1_HUMAN
θ value	6.88961 (rank : 144)	NC score	0.018436 (rank : 177)
Query Neighborhood Hits	173	Target Neighborhood Hits	157	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UBK2, Q9UN32	Gene names	PPARGC1A, LEM6, PGC1, PGC1A, PPARGC1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha) (Ligand effect modulator 6).

SRRM2_HUMAN
θ value	6.88961 (rank : 145)	NC score	0.058303 (rank : 100)
Query Neighborhood Hits	173	Target Neighborhood Hits	1296	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SYNJ1_MOUSE
θ value	6.88961 (rank : 146)	NC score	0.049806 (rank : 119)
Query Neighborhood Hits	173	Target Neighborhood Hits	516	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TENS1_HUMAN
θ value	6.88961 (rank : 147)	NC score	0.027168 (rank : 154)
Query Neighborhood Hits	173	Target Neighborhood Hits	400	Shared Neighborhood Hits	35
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

ZBT7A_HUMAN
θ value	6.88961 (rank : 148)	NC score	-0.001835 (rank : 213)
Query Neighborhood Hits	173	Target Neighborhood Hits	823	Shared Neighborhood Hits	12
SwissProt Accessions	O95365, O00456	Gene names	ZBTB7A, FBI1, LRF, ZBTB7
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma- related factor) (Factor that binds to inducer of short transcripts protein 1) (Factor binding IST protein 1) (FBI-1) (HIV-1 1st-binding protein 1) (TTF-I-interacting peptide 21) (TIP21).

BCAR1_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.026217 (rank : 157)
Query Neighborhood Hits	173	Target Neighborhood Hits	554	Shared Neighborhood Hits	46
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CECR6_MOUSE
θ value	8.99809 (rank : 150)	NC score	0.015006 (rank : 187)
Query Neighborhood Hits	173	Target Neighborhood Hits	22	Shared Neighborhood Hits	7
SwissProt Accessions	Q99MX7	Gene names	Cecr6
Domain Architecture	No domain graphic available
Description	Cat eye syndrome critical region protein 6 homolog.

CIC_HUMAN
θ value	8.99809 (rank : 151)	NC score	0.039622 (rank : 133)
Query Neighborhood Hits	173	Target Neighborhood Hits	992	Shared Neighborhood Hits	72
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CMGA_MOUSE
θ value	8.99809 (rank : 152)	NC score	0.025560 (rank : 160)
Query Neighborhood Hits	173	Target Neighborhood Hits	172	Shared Neighborhood Hits	16
SwissProt Accessions	P26339	Gene names	Chga
Domain Architecture
Description	Chromogranin A precursor (CgA) [Contains: Pancreastatin; Beta-granin; WE-14].

COT2_HUMAN
θ value	8.99809 (rank : 153)	NC score	0.002605 (rank : 207)
Query Neighborhood Hits	173	Target Neighborhood Hits	135	Shared Neighborhood Hits	5
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT2_MOUSE
θ value	8.99809 (rank : 154)	NC score	0.002605 (rank : 208)
Query Neighborhood Hits	173	Target Neighborhood Hits	135	Shared Neighborhood Hits	5
SwissProt Accessions	P43135	Gene names	Nr2f2, Aporp1, Arp-1, Arp1, Tfcoup2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

DACH1_HUMAN
θ value	8.99809 (rank : 155)	NC score	0.018812 (rank : 176)
Query Neighborhood Hits	173	Target Neighborhood Hits	214	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UI36, O75523, O75687, Q5VYY3, Q5VYY4, Q96SG3, Q96SG4, Q9H524, Q9UMH4	Gene names	DACH1, DACH
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

DACH1_MOUSE
θ value	8.99809 (rank : 156)	NC score	0.017304 (rank : 183)
Query Neighborhood Hits	173	Target Neighborhood Hits	228	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QYB2, O88716, Q8BPQ0, Q8C8D7, Q9QY47, Q9R218, Q9Z0Y5	Gene names	Dach1, Dach
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

DPOLZ_HUMAN
θ value	8.99809 (rank : 157)	NC score	0.009179 (rank : 198)
Query Neighborhood Hits	173	Target Neighborhood Hits	200	Shared Neighborhood Hits	9
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

FOXN1_MOUSE
θ value	8.99809 (rank : 158)	NC score	0.012745 (rank : 193)
Query Neighborhood Hits	173	Target Neighborhood Hits	300	Shared Neighborhood Hits	17
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

JPH2_HUMAN
θ value	8.99809 (rank : 159)	NC score	0.025378 (rank : 161)
Query Neighborhood Hits	173	Target Neighborhood Hits	639	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

JUNB_HUMAN
θ value	8.99809 (rank : 160)	NC score	0.014469 (rank : 189)
Query Neighborhood Hits	173	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	P17275, Q96GH3	Gene names	JUNB
Domain Architecture
Description	Transcription factor jun-B.

MAML3_HUMAN
θ value	8.99809 (rank : 161)	NC score	0.035668 (rank : 139)
Query Neighborhood Hits	173	Target Neighborhood Hits	323	Shared Neighborhood Hits	33
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

NCOA6_HUMAN
θ value	8.99809 (rank : 162)	NC score	0.053620 (rank : 108)
Query Neighborhood Hits	173	Target Neighborhood Hits	1202	Shared Neighborhood Hits	78
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NCOA6_MOUSE
θ value	8.99809 (rank : 163)	NC score	0.061022 (rank : 94)
Query Neighborhood Hits	173	Target Neighborhood Hits	1076	Shared Neighborhood Hits	73
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PAX9_HUMAN
θ value	8.99809 (rank : 164)	NC score	0.016799 (rank : 184)
Query Neighborhood Hits	173	Target Neighborhood Hits	92	Shared Neighborhood Hits	9
SwissProt Accessions	P55771, Q99582, Q9UQR4	Gene names	PAX9
Domain Architecture
Description	Paired box protein Pax-9.

SOX13_MOUSE
θ value	8.99809 (rank : 165)	NC score	0.016066 (rank : 186)
Query Neighborhood Hits	173	Target Neighborhood Hits	495	Shared Neighborhood Hits	31
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SPT5H_HUMAN
θ value	8.99809 (rank : 166)	NC score	0.027289 (rank : 153)
Query Neighborhood Hits	173	Target Neighborhood Hits	436	Shared Neighborhood Hits	38
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	8.99809 (rank : 167)	NC score	0.027679 (rank : 152)
Query Neighborhood Hits	173	Target Neighborhood Hits	437	Shared Neighborhood Hits	39
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

TAU_MOUSE
θ value	8.99809 (rank : 168)	NC score	0.024244 (rank : 163)
Query Neighborhood Hits	173	Target Neighborhood Hits	502	Shared Neighborhood Hits	38
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TITIN_HUMAN
θ value	8.99809 (rank : 169)	NC score	0.007609 (rank : 200)
Query Neighborhood Hits	173	Target Neighborhood Hits	2923	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

WBP4_MOUSE
θ value	8.99809 (rank : 170)	NC score	0.085363 (rank : 69)
Query Neighborhood Hits	173	Target Neighborhood Hits	100	Shared Neighborhood Hits	29
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

YSK4_HUMAN
θ value	8.99809 (rank : 171)	NC score	0.000352 (rank : 212)
Query Neighborhood Hits	173	Target Neighborhood Hits	921	Shared Neighborhood Hits	14
SwissProt Accessions	Q56UN5, Q56UN1, Q56UN2, Q56UN3, Q56UN4, Q8N4E9, Q9H5T2	Gene names	YSK4, RCK
Domain Architecture	No domain graphic available
Description	SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1) (Regulated in COPD, protein kinase).

ZN385_HUMAN
θ value	8.99809 (rank : 172)	NC score	0.020758 (rank : 169)
Query Neighborhood Hits	173	Target Neighborhood Hits	614	Shared Neighborhood Hits	34
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

ZN750_HUMAN
θ value	8.99809 (rank : 173)	NC score	0.019838 (rank : 173)
Query Neighborhood Hits	173	Target Neighborhood Hits	183	Shared Neighborhood Hits	25
SwissProt Accessions	Q32MQ0, Q9H899	Gene names	ZNF750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

APBB2_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.089533 (rank : 67)
Query Neighborhood Hits	173	Target Neighborhood Hits	96	Shared Neighborhood Hits	29
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

APBB2_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.082890 (rank : 72)
Query Neighborhood Hits	173	Target Neighborhood Hits	88	Shared Neighborhood Hits	28
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

APBB3_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.071723 (rank : 78)
Query Neighborhood Hits	173	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	O95704, Q9NYX6, Q9NYX7, Q9NYX8	Gene names	APBB3, FE65L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2).

APBB3_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.071289 (rank : 79)
Query Neighborhood Hits	173	Target Neighborhood Hits	32	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R1C9	Gene names	Apbb3
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 3.

BAT2_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.050072 (rank : 118)
Query Neighborhood Hits	173	Target Neighborhood Hits	931	Shared Neighborhood Hits	74
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CK024_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.050149 (rank : 117)
Query Neighborhood Hits	173	Target Neighborhood Hits	408	Shared Neighborhood Hits	45
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

EDD1_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.123816 (rank : 56)
Query Neighborhood Hits	173	Target Neighborhood Hits	170	Shared Neighborhood Hits	16
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

EDD1_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.123855 (rank : 54)
Query Neighborhood Hits	173	Target Neighborhood Hits	167	Shared Neighborhood Hits	16
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

GSCR1_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.050928 (rank : 114)
Query Neighborhood Hits	173	Target Neighborhood Hits	674	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HECD1_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.111461 (rank : 61)
Query Neighborhood Hits	173	Target Neighborhood Hits	371	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

HECD2_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.176140 (rank : 43)
Query Neighborhood Hits	173	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HECD2_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.177155 (rank : 42)
Query Neighborhood Hits	173	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CDU6, Q8CBQ9	Gene names	Hectd2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HECD3_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.121601 (rank : 57)
Query Neighborhood Hits	173	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	Q5T447, Q5T448, Q9H783	Gene names	HECTD3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HECD3_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.123820 (rank : 55)
Query Neighborhood Hits	173	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q3U487, Q3TN76, Q641P3, Q8BQ74, Q8R1L6	Gene names	Hectd3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HERC2_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.116711 (rank : 60)
Query Neighborhood Hits	173	Target Neighborhood Hits	163	Shared Neighborhood Hits	19
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC2_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.118112 (rank : 59)
Query Neighborhood Hits	173	Target Neighborhood Hits	167	Shared Neighborhood Hits	19
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC3_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.143277 (rank : 52)
Query Neighborhood Hits	173	Target Neighborhood Hits	62	Shared Neighborhood Hits	14
SwissProt Accessions	Q15034	Gene names	HERC3, KIAA0032
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain protein 3.

HERC5_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.147342 (rank : 51)
Query Neighborhood Hits	173	Target Neighborhood Hits	66	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UII4	Gene names	HERC5, CEB1, CEBP1
Domain Architecture
Description	HECT domain and RCC1-like domain-containing protein 5 (Cyclin-E- binding protein 1).

HUWE1_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.185676 (rank : 40)
Query Neighborhood Hits	173	Target Neighborhood Hits	443	Shared Neighborhood Hits	37
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.185362 (rank : 41)
Query Neighborhood Hits	173	Target Neighborhood Hits	406	Shared Neighborhood Hits	34
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

K0317_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.185700 (rank : 38)
Query Neighborhood Hits	173	Target Neighborhood Hits	46	Shared Neighborhood Hits	13
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K0317_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.185683 (rank : 39)
Query Neighborhood Hits	173	Target Neighborhood Hits	43	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CHG5, Q6P9Q1, Q80YC4, Q8C5W5	Gene names	Kiaa0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K1849_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.051019 (rank : 113)
Query Neighborhood Hits	173	Target Neighborhood Hits	220	Shared Neighborhood Hits	18
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

MUC1_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.051397 (rank : 112)
Query Neighborhood Hits	173	Target Neighborhood Hits	975	Shared Neighborhood Hits	70
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

PCLO_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.064650 (rank : 87)
Query Neighborhood Hits	173	Target Neighborhood Hits	2046	Shared Neighborhood Hits	100
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PRB3_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.056313 (rank : 104)
Query Neighborhood Hits	173	Target Neighborhood Hits	318	Shared Neighborhood Hits	37
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.055329 (rank : 106)
Query Neighborhood Hits	173	Target Neighborhood Hits	330	Shared Neighborhood Hits	41
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRP1_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.050588 (rank : 116)
Query Neighborhood Hits	173	Target Neighborhood Hits	385	Shared Neighborhood Hits	45
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.062444 (rank : 91)
Query Neighborhood Hits	173	Target Neighborhood Hits	347	Shared Neighborhood Hits	42
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

SRRM1_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.056122 (rank : 105)
Query Neighborhood Hits	173	Target Neighborhood Hits	690	Shared Neighborhood Hits	58
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.057829 (rank : 102)
Query Neighborhood Hits	173	Target Neighborhood Hits	966	Shared Neighborhood Hits	73
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.053079 (rank : 109)
Query Neighborhood Hits	173	Target Neighborhood Hits	1470	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TCRG1_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.067492 (rank : 81)
Query Neighborhood Hits	173	Target Neighborhood Hits	929	Shared Neighborhood Hits	66
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.066929 (rank : 83)
Query Neighborhood Hits	173	Target Neighborhood Hits	947	Shared Neighborhood Hits	66
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TRIPC_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.162572 (rank : 48)
Query Neighborhood Hits	173	Target Neighborhood Hits	319	Shared Neighborhood Hits	30
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

UBE3A_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.171838 (rank : 44)
Query Neighborhood Hits	173	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

UBE3A_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.169506 (rank : 46)
Query Neighborhood Hits	173	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	O08759, P97482	Gene names	Ube3a
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic protein- associated protein E6-AP).

UBE3C_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.169990 (rank : 45)
Query Neighborhood Hits	173	Target Neighborhood Hits	51	Shared Neighborhood Hits	13
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

UBE3C_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.169371 (rank : 47)
Query Neighborhood Hits	173	Target Neighborhood Hits	48	Shared Neighborhood Hits	13
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

WWC3_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.059713 (rank : 96)
Query Neighborhood Hits	173	Target Neighborhood Hits	193	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ULE0, Q659C1, Q9BTQ1	Gene names	WWC3, KIAA1280
Domain Architecture	No domain graphic available
Description	WWC family member 3.

Hits sorted by NC score

YAP1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	173	Target Neighborhood Hits	173	Shared Neighborhood Hits	173
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

YAP1_MOUSE
NC score	0.936833 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	173	Target Neighborhood Hits	96	Shared Neighborhood Hits	72
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

WWTR1_HUMAN
NC score	0.923719 (rank : 3)	θ value	5.69867e-79 (rank : 4)
Query Neighborhood Hits	173	Target Neighborhood Hits	76	Shared Neighborhood Hits	49
SwissProt Accessions	Q9GZV5, Q8N3P2, Q9Y3W6	Gene names	WWTR1, TAZ
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

WWTR1_MOUSE
NC score	0.922775 (rank : 4)	θ value	4.36332e-79 (rank : 3)
Query Neighborhood Hits	173	Target Neighborhood Hits	54	Shared Neighborhood Hits	41
SwissProt Accessions	Q9EPK5, Q99KI4	Gene names	Wwtr1, Taz
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

SAV1_HUMAN
NC score	0.448007 (rank : 5)	θ value	0.00509761 (rank : 31)
Query Neighborhood Hits	173	Target Neighborhood Hits	51	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

SAV1_MOUSE
NC score	0.446855 (rank : 6)	θ value	0.00509761 (rank : 32)
Query Neighborhood Hits	173	Target Neighborhood Hits	48	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VEB2, Q9D9N9, Q9ER46	Gene names	Sav1, Ww45, Wwp3
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (mWW45).

WWC1_HUMAN
NC score	0.395532 (rank : 7)	θ value	0.000158464 (rank : 23)
Query Neighborhood Hits	173	Target Neighborhood Hits	290	Shared Neighborhood Hits	43
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

WWC1_MOUSE
NC score	0.390157 (rank : 8)	θ value	0.000270298 (rank : 26)
Query Neighborhood Hits	173	Target Neighborhood Hits	290	Shared Neighborhood Hits	36
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

WWP1_MOUSE
NC score	0.384374 (rank : 9)	θ value	8.40245e-06 (rank : 8)
Query Neighborhood Hits	173	Target Neighborhood Hits	138	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

WWP2_HUMAN
NC score	0.379611 (rank : 10)	θ value	9.29e-05 (rank : 20)
Query Neighborhood Hits	173	Target Neighborhood Hits	177	Shared Neighborhood Hits	62
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

WWP2_MOUSE
NC score	0.378511 (rank : 11)	θ value	9.29e-05 (rank : 21)
Query Neighborhood Hits	173	Target Neighborhood Hits	118	Shared Neighborhood Hits	52
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

WWP1_HUMAN
NC score	0.377542 (rank : 12)	θ value	7.1131e-05 (rank : 18)
Query Neighborhood Hits	173	Target Neighborhood Hits	262	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

BAG3_HUMAN
NC score	0.375350 (rank : 13)	θ value	0.000602161 (rank : 29)
Query Neighborhood Hits	173	Target Neighborhood Hits	314	Shared Neighborhood Hits	72
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

ITCH_MOUSE
NC score	0.373802 (rank : 14)	θ value	5.44631e-05 (rank : 16)
Query Neighborhood Hits	173	Target Neighborhood Hits	127	Shared Neighborhood Hits	53
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

ITCH_HUMAN
NC score	0.372774 (rank : 15)	θ value	9.29e-05 (rank : 19)
Query Neighborhood Hits	173	Target Neighborhood Hits	162	Shared Neighborhood Hits	58
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

SMUF2_HUMAN
NC score	0.360270 (rank : 16)	θ value	0.00035302 (rank : 27)
Query Neighborhood Hits	173	Target Neighborhood Hits	142	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

SMUF1_MOUSE
NC score	0.352506 (rank : 17)	θ value	4.1701e-05 (rank : 13)
Query Neighborhood Hits	173	Target Neighborhood Hits	142	Shared Neighborhood Hits	40
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

NED4L_MOUSE
NC score	0.351226 (rank : 18)	θ value	1.09739e-05 (rank : 10)
Query Neighborhood Hits	173	Target Neighborhood Hits	231	Shared Neighborhood Hits	55
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NEDD4_HUMAN
NC score	0.350602 (rank : 19)	θ value	0.00020696 (rank : 24)
Query Neighborhood Hits	173	Target Neighborhood Hits	214	Shared Neighborhood Hits	51
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

NED4L_HUMAN
NC score	0.349452 (rank : 20)	θ value	3.19293e-05 (rank : 12)
Query Neighborhood Hits	173	Target Neighborhood Hits	238	Shared Neighborhood Hits	56
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

SMUF1_HUMAN
NC score	0.349274 (rank : 21)	θ value	3.77169e-06 (rank : 5)
Query Neighborhood Hits	173	Target Neighborhood Hits	135	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

NEDD4_MOUSE
NC score	0.346506 (rank : 22)	θ value	0.000461057 (rank : 28)
Query Neighborhood Hits	173	Target Neighborhood Hits	212	Shared Neighborhood Hits	54
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

WWOX_HUMAN
NC score	0.345427 (rank : 23)	θ value	4.1701e-05 (rank : 14)
Query Neighborhood Hits	173	Target Neighborhood Hits	115	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NZC7, Q5MYT5, Q96KM3, Q96RF2, Q9BTT8, Q9NPC9, Q9NRF4, Q9NRF5, Q9NRF6, Q9NRK1, Q9NZC5	Gene names	WWOX, FOR, WOX1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase).

BAG3_MOUSE
NC score	0.343166 (rank : 24)	θ value	7.1131e-05 (rank : 17)
Query Neighborhood Hits	173	Target Neighborhood Hits	513	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

WWOX_MOUSE
NC score	0.342441 (rank : 25)	θ value	4.1701e-05 (rank : 15)
Query Neighborhood Hits	173	Target Neighborhood Hits	118	Shared Neighborhood Hits	46
SwissProt Accessions	Q91WL8, Q8C8J6, Q920Y2, Q9D2B3, Q9D339, Q9JLF5	Gene names	Wwox, Wox1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-).

MAGI2_MOUSE
NC score	0.328476 (rank : 26)	θ value	1.09739e-05 (rank : 9)
Query Neighborhood Hits	173	Target Neighborhood Hits	370	Shared Neighborhood Hits	66
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

MAGI2_HUMAN
NC score	0.319076 (rank : 27)	θ value	1.87187e-05 (rank : 11)
Query Neighborhood Hits	173	Target Neighborhood Hits	373	Shared Neighborhood Hits	58
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

PINL_HUMAN
NC score	0.316863 (rank : 28)	θ value	0.62314 (rank : 66)
Query Neighborhood Hits	173	Target Neighborhood Hits	47	Shared Neighborhood Hits	40
SwissProt Accessions	O15428	Gene names	PIN1L
Domain Architecture
Description	PIN1-like protein.

MAGI1_MOUSE
NC score	0.309695 (rank : 29)	θ value	6.43352e-06 (rank : 7)
Query Neighborhood Hits	173	Target Neighborhood Hits	403	Shared Neighborhood Hits	54
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

PIN1_MOUSE
NC score	0.309536 (rank : 30)	θ value	0.163984 (rank : 49)
Query Neighborhood Hits	173	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

MAGI1_HUMAN
NC score	0.308069 (rank : 31)	θ value	6.43352e-06 (rank : 6)
Query Neighborhood Hits	173	Target Neighborhood Hits	388	Shared Neighborhood Hits	54
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

PIN1_HUMAN
NC score	0.297867 (rank : 32)	θ value	0.163984 (rank : 48)
Query Neighborhood Hits	173	Target Neighborhood Hits	59	Shared Neighborhood Hits	40
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

STXB4_MOUSE
NC score	0.238853 (rank : 33)	θ value	0.00020696 (rank : 25)
Query Neighborhood Hits	173	Target Neighborhood Hits	629	Shared Neighborhood Hits	47
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

PKHA5_HUMAN
NC score	0.237511 (rank : 34)	θ value	0.0193708 (rank : 33)
Query Neighborhood Hits	173	Target Neighborhood Hits	455	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

STXB4_HUMAN
NC score	0.235143 (rank : 35)	θ value	0.000158464 (rank : 22)
Query Neighborhood Hits	173	Target Neighborhood Hits	616	Shared Neighborhood Hits	47
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

GAS7_MOUSE
NC score	0.222229 (rank : 36)	θ value	0.62314 (rank : 62)
Query Neighborhood Hits	173	Target Neighborhood Hits	259	Shared Neighborhood Hits	42
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

GAS7_HUMAN
NC score	0.212241 (rank : 37)	θ value	0.279714 (rank : 57)
Query Neighborhood Hits	173	Target Neighborhood Hits	258	Shared Neighborhood Hits	43
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

K0317_HUMAN
NC score	0.185700 (rank : 38)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	173	Target Neighborhood Hits	46	Shared Neighborhood Hits	13
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K0317_MOUSE
NC score	0.185683 (rank : 39)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	173	Target Neighborhood Hits	43	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CHG5, Q6P9Q1, Q80YC4, Q8C5W5	Gene names	Kiaa0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

HUWE1_HUMAN
NC score	0.185676 (rank : 40)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	173	Target Neighborhood Hits	443	Shared Neighborhood Hits	37
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
NC score	0.185362 (rank : 41)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	173	Target Neighborhood Hits	406	Shared Neighborhood Hits	34
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

HECD2_MOUSE
NC score	0.177155 (rank : 42)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	173	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CDU6, Q8CBQ9	Gene names	Hectd2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HECD2_HUMAN
NC score	0.176140 (rank : 43)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	173	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

UBE3A_HUMAN
NC score	0.171838 (rank : 44)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	173	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

UBE3C_HUMAN
NC score	0.169990 (rank : 45)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	173	Target Neighborhood Hits	51	Shared Neighborhood Hits	13
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

UBE3A_MOUSE
NC score	0.169506 (rank : 46)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	173	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	O08759, P97482	Gene names	Ube3a
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic protein- associated protein E6-AP).

UBE3C_MOUSE
NC score	0.169371 (rank : 47)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	173	Target Neighborhood Hits	48	Shared Neighborhood Hits	13
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

TRIPC_HUMAN
NC score	0.162572 (rank : 48)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	173	Target Neighborhood Hits	319	Shared Neighborhood Hits	30
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

PRP40_HUMAN
NC score	0.155614 (rank : 49)	θ value	0.0330416 (rank : 37)
Query Neighborhood Hits	173	Target Neighborhood Hits	442	Shared Neighborhood Hits	45
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

PRP40_MOUSE
NC score	0.148059 (rank : 50)	θ value	0.279714 (rank : 59)
Query Neighborhood Hits	173	Target Neighborhood Hits	447	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

HERC5_HUMAN
NC score	0.147342 (rank : 51)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	173	Target Neighborhood Hits	66	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UII4	Gene names	HERC5, CEB1, CEBP1
Domain Architecture
Description	HECT domain and RCC1-like domain-containing protein 5 (Cyclin-E- binding protein 1).

HERC3_HUMAN
NC score	0.143277 (rank : 52)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	173	Target Neighborhood Hits	62	Shared Neighborhood Hits	14
SwissProt Accessions	Q15034	Gene names	HERC3, KIAA0032
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain protein 3.

DRP2_HUMAN
NC score	0.130469 (rank : 53)	θ value	0.0330416 (rank : 36)
Query Neighborhood Hits	173	Target Neighborhood Hits	186	Shared Neighborhood Hits	25
SwissProt Accessions	Q13474	Gene names	DRP2
Domain Architecture
Description	Dystrophin-related protein 2.

EDD1_MOUSE
NC score	0.123855 (rank : 54)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	173	Target Neighborhood Hits	167	Shared Neighborhood Hits	16
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

HECD3_MOUSE
NC score	0.123820 (rank : 55)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	173	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q3U487, Q3TN76, Q641P3, Q8BQ74, Q8R1L6	Gene names	Hectd3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

EDD1_HUMAN
NC score	0.123816 (rank : 56)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	173	Target Neighborhood Hits	170	Shared Neighborhood Hits	16
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

HECD3_HUMAN
NC score	0.121601 (rank : 57)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	173	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	Q5T447, Q5T448, Q9H783	Gene names	HECTD3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

SETD2_HUMAN
NC score	0.118953 (rank : 58)	θ value	0.0736092 (rank : 43)
Query Neighborhood Hits	173	Target Neighborhood Hits	412	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

HERC2_MOUSE
NC score	0.118112 (rank : 59)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	173	Target Neighborhood Hits	167	Shared Neighborhood Hits	19
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC2_HUMAN
NC score	0.116711 (rank : 60)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	173	Target Neighborhood Hits	163	Shared Neighborhood Hits	19
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HECD1_HUMAN
NC score	0.111461 (rank : 61)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	173	Target Neighborhood Hits	371	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

SGIP1_MOUSE
NC score	0.107991 (rank : 62)	θ value	0.00298849 (rank : 30)
Query Neighborhood Hits	173	Target Neighborhood Hits	180	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

RHG12_MOUSE
NC score	0.105374 (rank : 63)	θ value	0.125558 (rank : 45)
Query Neighborhood Hits	173	Target Neighborhood Hits	204	Shared Neighborhood Hits	34
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

APBB1_HUMAN
NC score	0.099189 (rank : 64)	θ value	0.0330416 (rank : 34)
Query Neighborhood Hits	173	Target Neighborhood Hits	62	Shared Neighborhood Hits	20
SwissProt Accessions	O00213, Q96A93	Gene names	APBB1, FE65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

APBB1_MOUSE
NC score	0.098023 (rank : 65)	θ value	0.0330416 (rank : 35)
Query Neighborhood Hits	173	Target Neighborhood Hits	75	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QXJ1, O08642, Q3TPU0, Q8BNF4, Q8BSR9	Gene names	Apbb1, Fe65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

RHG12_HUMAN
NC score	0.094919 (rank : 66)	θ value	0.21417 (rank : 55)
Query Neighborhood Hits	173	Target Neighborhood Hits	190	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

APBB2_HUMAN
NC score	0.089533 (rank : 67)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	173	Target Neighborhood Hits	96	Shared Neighborhood Hits	29
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

MDC1_HUMAN
NC score	0.089332 (rank : 68)	θ value	0.0431538 (rank : 38)
Query Neighborhood Hits	173	Target Neighborhood Hits	1446	Shared Neighborhood Hits	79
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

WBP4_MOUSE
NC score	0.085363 (rank : 69)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	173	Target Neighborhood Hits	100	Shared Neighborhood Hits	29
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

MDC1_MOUSE
NC score	0.083280 (rank : 70)	θ value	0.0736092 (rank : 41)
Query Neighborhood Hits	173	Target Neighborhood Hits	998	Shared Neighborhood Hits	68
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

PCLO_MOUSE
NC score	0.083168 (rank : 71)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	173	Target Neighborhood Hits	2275	Shared Neighborhood Hits	111
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

APBB2_MOUSE
NC score	0.082890 (rank : 72)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	173	Target Neighborhood Hits	88	Shared Neighborhood Hits	28
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

DGCR8_HUMAN
NC score	0.078544 (rank : 73)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	173	Target Neighborhood Hits	72	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WYQ5, Q6DCB2, Q6MZE9, Q6Y2L0, Q96G39, Q96GP8, Q9H6L8, Q9H6T7, Q9NRW2	Gene names	DGCR8, C22orf12, DGCRK6
Domain Architecture
Description	DGCR8 protein (DiGeorge syndrome critical region 8).

SGIP1_HUMAN
NC score	0.077651 (rank : 74)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	173	Target Neighborhood Hits	198	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

DGCR8_MOUSE
NC score	0.075305 (rank : 75)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	173	Target Neighborhood Hits	70	Shared Neighborhood Hits	14
SwissProt Accessions	Q9EQM6	Gene names	Dgcr8
Domain Architecture	No domain graphic available
Description	DGCR8 protein (DiGeorge syndrome critical region 8 homolog) (Gy1).

PI5PA_HUMAN
NC score	0.074433 (rank : 76)	θ value	0.279714 (rank : 58)
Query Neighborhood Hits	173	Target Neighborhood Hits	749	Shared Neighborhood Hits	62
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

RGS3_MOUSE
NC score	0.072596 (rank : 77)	θ value	0.0431538 (rank : 39)
Query Neighborhood Hits	173	Target Neighborhood Hits	1621	Shared Neighborhood Hits	94
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

APBB3_HUMAN
NC score	0.071723 (rank : 78)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	173	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	O95704, Q9NYX6, Q9NYX7, Q9NYX8	Gene names	APBB3, FE65L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2).

APBB3_MOUSE
NC score	0.071289 (rank : 79)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	173	Target Neighborhood Hits	32	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R1C9	Gene names	Apbb3
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 3.

NDUB5_MOUSE
NC score	0.067957 (rank : 80)	θ value	0.0736092 (rank : 42)
Query Neighborhood Hits	173	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CQH3	Gene names	Ndufb5
Domain Architecture	No domain graphic available
Description	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial precursor (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase SGDH subunit) (Complex I-SGDH) (CI-SGDH).

TCRG1_HUMAN
NC score	0.067492 (rank : 81)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	173	Target Neighborhood Hits	929	Shared Neighborhood Hits	66
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

MUC7_HUMAN
NC score	0.067150 (rank : 82)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	173	Target Neighborhood Hits	538	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

TCRG1_MOUSE
NC score	0.066929 (rank : 83)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	173	Target Neighborhood Hits	947	Shared Neighborhood Hits	66
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

NACAM_MOUSE
NC score	0.066845 (rank : 84)	θ value	0.365318 (rank : 61)
Query Neighborhood Hits	173	Target Neighborhood Hits	1866	Shared Neighborhood Hits	97
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PI5PA_MOUSE
NC score	0.066253 (rank : 85)	θ value	0.62314 (rank : 65)
Query Neighborhood Hits	173	Target Neighborhood Hits	331	Shared Neighborhood Hits	44
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

RGS3_HUMAN
NC score	0.066006 (rank : 86)	θ value	0.21417 (rank : 54)
Query Neighborhood Hits	173	Target Neighborhood Hits	1375	Shared Neighborhood Hits	76
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

PCLO_HUMAN
NC score	0.064650 (rank : 87)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	173	Target Neighborhood Hits	2046	Shared Neighborhood Hits	100
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

DMD_HUMAN
NC score	0.064565 (rank : 88)	θ value	0.21417 (rank : 52)
Query Neighborhood Hits	173	Target Neighborhood Hits	1135	Shared Neighborhood Hits	38
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

BSN_MOUSE
NC score	0.063861 (rank : 89)	θ value	0.21417 (rank : 51)
Query Neighborhood Hits	173	Target Neighborhood Hits	2057	Shared Neighborhood Hits	92
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CK024_MOUSE
NC score	0.062572 (rank : 90)	θ value	0.813845 (rank : 71)
Query Neighborhood Hits	173	Target Neighborhood Hits	307	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

PRP2_MOUSE
NC score	0.062444 (rank : 91)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	173	Target Neighborhood Hits	347	Shared Neighborhood Hits	42
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

BSN_HUMAN
NC score	0.061665 (rank : 92)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	173	Target Neighborhood Hits	1537	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

DMD_MOUSE
NC score	0.061143 (rank : 93)	θ value	0.21417 (rank : 53)
Query Neighborhood Hits	173	Target Neighborhood Hits	1111	Shared Neighborhood Hits	38
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

NCOA6_MOUSE
NC score	0.061022 (rank : 94)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	173	Target Neighborhood Hits	1076	Shared Neighborhood Hits	73
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

INP5E_HUMAN
NC score	0.060795 (rank : 95)	θ value	0.0736092 (rank : 40)
Query Neighborhood Hits	173	Target Neighborhood Hits	201	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

WWC3_HUMAN
NC score	0.059713 (rank : 96)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	173	Target Neighborhood Hits	193	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ULE0, Q659C1, Q9BTQ1	Gene names	WWC3, KIAA1280
Domain Architecture	No domain graphic available
Description	WWC family member 3.

UTRO_HUMAN
NC score	0.059702 (rank : 97)	θ value	0.163984 (rank : 50)
Query Neighborhood Hits	173	Target Neighborhood Hits	960	Shared Neighborhood Hits	40
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

OGFR_HUMAN
NC score	0.059235 (rank : 98)	θ value	0.813845 (rank : 72)
Query Neighborhood Hits	173	Target Neighborhood Hits	1582	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

WHRN_MOUSE
NC score	0.058615 (rank : 99)	θ value	0.62314 (rank : 67)
Query Neighborhood Hits	173	Target Neighborhood Hits	412	Shared Neighborhood Hits	24
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

SRRM2_HUMAN
NC score	0.058303 (rank : 100)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	173	Target Neighborhood Hits	1296	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

GRIN1_MOUSE
NC score	0.058151 (rank : 101)	θ value	1.06291 (rank : 73)
Query Neighborhood Hits	173	Target Neighborhood Hits	337	Shared Neighborhood Hits	37
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

SRRM1_MOUSE
NC score	0.057829 (rank : 102)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	173	Target Neighborhood Hits	966	Shared Neighborhood Hits	73
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

CN152_HUMAN
NC score	0.056437 (rank : 103)	θ value	2.36792 (rank : 87)
Query Neighborhood Hits	173	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N9Y4, Q96GY1	Gene names	C14orf152
Domain Architecture	No domain graphic available
Description	Protein C14orf152.

PRB3_HUMAN
NC score	0.056313 (rank : 104)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	173	Target Neighborhood Hits	318	Shared Neighborhood Hits	37
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

SRRM1_HUMAN
NC score	0.056122 (rank : 105)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	173	Target Neighborhood Hits	690	Shared Neighborhood Hits	58
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

PRB4S_HUMAN
NC score	0.055329 (rank : 106)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	173	Target Neighborhood Hits	330	Shared Neighborhood Hits	41
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

SAPS1_HUMAN
NC score	0.053881 (rank : 107)	θ value	0.125558 (rank : 46)
Query Neighborhood Hits	173	Target Neighborhood Hits	704	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

NCOA6_HUMAN
NC score	0.053620 (rank : 108)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	173	Target Neighborhood Hits	1202	Shared Neighborhood Hits	78
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

SRRM2_MOUSE
NC score	0.053079 (rank : 109)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	173	Target Neighborhood Hits	1470	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

BIM_MOUSE
NC score	0.051865 (rank : 110)	θ value	0.279714 (rank : 56)
Query Neighborhood Hits	173	Target Neighborhood Hits	124	Shared Neighborhood Hits	10
SwissProt Accessions	O54918, O54919, O54920	Gene names	Bcl2l11, Bim
Domain Architecture
Description	Bcl-2-like protein 11 (Bcl2-interacting mediator of cell death).

LAD1_MOUSE
NC score	0.051408 (rank : 111)	θ value	1.06291 (rank : 75)
Query Neighborhood Hits	173	Target Neighborhood Hits	391	Shared Neighborhood Hits	33
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

MUC1_HUMAN
NC score	0.051397 (rank : 112)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	173	Target Neighborhood Hits	975	Shared Neighborhood Hits	70
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

K1849_HUMAN
NC score	0.051019 (rank : 113)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	173	Target Neighborhood Hits	220	Shared Neighborhood Hits	18
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

GSCR1_HUMAN
NC score	0.050928 (rank : 114)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	173	Target Neighborhood Hits	674	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

ANC1_MOUSE
NC score	0.050745 (rank : 115)	θ value	0.813845 (rank : 70)
Query Neighborhood Hits	173	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	P53995, Q8BP33, Q8C772	Gene names	Anapc1, Mcpr, Tsg24
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Protein Tsg24) (Mitotic checkpoint regulator).

PRP1_HUMAN
NC score	0.050588 (rank : 116)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	173	Target Neighborhood Hits	385	Shared Neighborhood Hits	45
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

CK024_HUMAN
NC score	0.050149 (rank : 117)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	173	Target Neighborhood Hits	408	Shared Neighborhood Hits	45
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

BAT2_HUMAN
NC score	0.050072 (rank : 118)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	173	Target Neighborhood Hits	931	Shared Neighborhood Hits	74
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

SYNJ1_MOUSE
NC score	0.049806 (rank : 119)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	173	Target Neighborhood Hits	516	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

MINT_HUMAN
NC score	0.047163 (rank : 120)	θ value	0.62314 (rank : 64)
Query Neighborhood Hits	173	Target Neighborhood Hits	1291	Shared Neighborhood Hits	71
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

ANC1_HUMAN
NC score	0.046964 (rank : 121)	θ value	2.36792 (rank : 86)
Query Neighborhood Hits	173	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H1A4, Q9BSE6, Q9H8D0	Gene names	ANAPC1, TSG24
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Protein Tsg24) (Mitotic checkpoint regulator).

SET1A_HUMAN
NC score	0.046727 (rank : 122)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	173	Target Neighborhood Hits	690	Shared Neighborhood Hits	54
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

RAPH1_HUMAN
NC score	0.046156 (rank : 123)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	173	Target Neighborhood Hits	593	Shared Neighborhood Hits	56
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

SYNPO_HUMAN
NC score	0.046039 (rank : 124)	θ value	1.06291 (rank : 78)
Query Neighborhood Hits	173	Target Neighborhood Hits	281	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

YLPM1_MOUSE
NC score	0.045698 (rank : 125)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	173	Target Neighborhood Hits	505	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

MUC13_MOUSE
NC score	0.044278 (rank : 126)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	173	Target Neighborhood Hits	447	Shared Neighborhood Hits	34
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

ASPP1_MOUSE
NC score	0.043982 (rank : 127)	θ value	0.365318 (rank : 60)
Query Neighborhood Hits	173	Target Neighborhood Hits	1244	Shared Neighborhood Hits	57
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ARI1B_HUMAN
NC score	0.043914 (rank : 128)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	173	Target Neighborhood Hits	567	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

BAT2_MOUSE
NC score	0.043878 (rank : 129)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	173	Target Neighborhood Hits	947	Shared Neighborhood Hits	69
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

RERE_HUMAN
NC score	0.042791 (rank : 130)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	173	Target Neighborhood Hits	779	Shared Neighborhood Hits	59
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

ASPP1_HUMAN
NC score	0.041195 (rank : 131)	θ value	0.0961366 (rank : 44)
Query Neighborhood Hits	173	Target Neighborhood Hits	956	Shared Neighborhood Hits	35
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

MAML1_MOUSE
NC score	0.039671 (rank : 132)	θ value	0.62314 (rank : 63)
Query Neighborhood Hits	173	Target Neighborhood Hits	279	Shared Neighborhood Hits	29
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

CIC_HUMAN
NC score	0.039622 (rank : 133)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	173	Target Neighborhood Hits	992	Shared Neighborhood Hits	72
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

RHG09_HUMAN
NC score	0.039321 (rank : 134)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	173	Target Neighborhood Hits	186	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

MUC5B_HUMAN
NC score	0.037600 (rank : 135)	θ value	1.06291 (rank : 76)
Query Neighborhood Hits	173	Target Neighborhood Hits	1020	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

CCP2_MOUSE
NC score	0.036963 (rank : 136)	θ value	0.163984 (rank : 47)
Query Neighborhood Hits	173	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JHG2	Gene names	Dscr1l1
Domain Architecture
Description	Calcipressin-2 (Down syndrome candidate region 1-like protein 1) (Myocyte-enriched calcineurin-interacting protein 2) (MCIP2).

K1802_MOUSE
NC score	0.036435 (rank : 137)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	173	Target Neighborhood Hits	1596	Shared Neighborhood Hits	75
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

NPBL_MOUSE
NC score	0.035743 (rank : 138)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	173	Target Neighborhood Hits	1041	Shared Neighborhood Hits	58
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

MAML3_HUMAN
NC score	0.035668 (rank : 139)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	173	Target Neighborhood Hits	323	Shared Neighborhood Hits	33
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

BAZ2A_MOUSE
NC score	0.035635 (rank : 140)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	173	Target Neighborhood Hits	744	Shared Neighborhood Hits	55
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

NEB2_MOUSE
NC score	0.035400 (rank : 141)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	173	Target Neighborhood Hits	889	Shared Neighborhood Hits	26
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

RP1L1_HUMAN
NC score	0.035067 (rank : 142)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	173	Target Neighborhood Hits	1072	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

EVI2B_MOUSE
NC score	0.032544 (rank : 143)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	173	Target Neighborhood Hits	87	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VD58, Q3U1A3	Gene names	Evi2b
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

HGS_MOUSE
NC score	0.032351 (rank : 144)	θ value	1.06291 (rank : 74)
Query Neighborhood Hits	173	Target Neighborhood Hits	589	Shared Neighborhood Hits	40
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HN1L_MOUSE
NC score	0.031929 (rank : 145)	θ value	1.81305 (rank : 82)
Query Neighborhood Hits	173	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PGH2	Gene names	D17Ertd441e
Domain Architecture	No domain graphic available
Description	Hematological and neurological expressed 1-like protein (HN1-like protein).

MTSS1_MOUSE
NC score	0.030629 (rank : 146)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	173	Target Neighborhood Hits	592	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

CEL_HUMAN
NC score	0.030572 (rank : 147)	θ value	3.0926 (rank : 93)
Query Neighborhood Hits	173	Target Neighborhood Hits	896	Shared Neighborhood Hits	56
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

PAX1_MOUSE
NC score	0.030202 (rank : 148)	θ value	1.06291 (rank : 77)
Query Neighborhood Hits	173	Target Neighborhood Hits	69	Shared Neighborhood Hits	10
SwissProt Accessions	P09084, Q9R2B1	Gene names	Pax1, Pax-1
Domain Architecture
Description	Paired box protein Pax-1.

CD2_HUMAN
NC score	0.030028 (rank : 149)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	173	Target Neighborhood Hits	504	Shared Neighborhood Hits	31
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

FILA_HUMAN
NC score	0.029713 (rank : 150)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	173	Target Neighborhood Hits	685	Shared Neighborhood Hits	30
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

TTC15_MOUSE
NC score	0.028675 (rank : 151)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	173	Target Neighborhood Hits	113	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K2L8, Q8BX27	Gene names	Ttc15
Domain Architecture
Description	Tetratricopeptide repeat protein 15 (TPR repeat protein 15).

SPT5H_MOUSE
NC score	0.027679 (rank : 152)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	173	Target Neighborhood Hits	437	Shared Neighborhood Hits	39
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SPT5H_HUMAN
NC score	0.027289 (rank : 153)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	173	Target Neighborhood Hits	436	Shared Neighborhood Hits	38
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

TENS1_HUMAN
NC score	0.027168 (rank : 154)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	173	Target Neighborhood Hits	400	Shared Neighborhood Hits	35
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

EP400_MOUSE
NC score	0.026786 (rank : 155)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	173	Target Neighborhood Hits	592	Shared Neighborhood Hits	55
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

PHC1_HUMAN
NC score	0.026756 (rank : 156)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	173	Target Neighborhood Hits	227	Shared Neighborhood Hits	31
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

BCAR1_HUMAN
NC score	0.026217 (rank : 157)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	173	Target Neighborhood Hits	554	Shared Neighborhood Hits	46
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

COA2_HUMAN
NC score	0.026035 (rank : 158)	θ value	2.36792 (rank : 88)
Query Neighborhood Hits	173	Target Neighborhood Hits	184	Shared Neighborhood Hits	23
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

PO6F2_MOUSE
NC score	0.025593 (rank : 159)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	173	Target Neighborhood Hits	639	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

CMGA_MOUSE
NC score	0.025560 (rank : 160)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	173	Target Neighborhood Hits	172	Shared Neighborhood Hits	16
SwissProt Accessions	P26339	Gene names	Chga
Domain Architecture
Description	Chromogranin A precursor (CgA) [Contains: Pancreastatin; Beta-granin; WE-14].

JPH2_HUMAN
NC score	0.025378 (rank : 161)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	173	Target Neighborhood Hits	639	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

UPK3B_HUMAN
NC score	0.024580 (rank : 162)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	173	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BT76, Q86W06	Gene names	UPK3B
Domain Architecture	No domain graphic available
Description	Uroplakin-3B precursor (Uroplakin IIIb) (UPIIIb) (p35).

TAU_MOUSE
NC score	0.024244 (rank : 163)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	173	Target Neighborhood Hits	502	Shared Neighborhood Hits	38
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

RC3H1_HUMAN
NC score	0.023600 (rank : 164)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	173	Target Neighborhood Hits	433	Shared Neighborhood Hits	28
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

CECR2_HUMAN
NC score	0.023330 (rank : 165)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	173	Target Neighborhood Hits	543	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

COHA1_HUMAN
NC score	0.022630 (rank : 166)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	173	Target Neighborhood Hits	400	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

K0240_MOUSE
NC score	0.021661 (rank : 167)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	173	Target Neighborhood Hits	211	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CHH5	Gene names	Kiaa0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

PAX1_HUMAN
NC score	0.021560 (rank : 168)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	173	Target Neighborhood Hits	72	Shared Neighborhood Hits	10
SwissProt Accessions	P15863, Q642X9, Q6NTC0, Q9Y558	Gene names	PAX1, HUP48
Domain Architecture
Description	Paired box protein Pax-1 (HUP48).

ZN385_HUMAN
NC score	0.020758 (rank : 169)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	173	Target Neighborhood Hits	614	Shared Neighborhood Hits	34
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

TTBK1_HUMAN
NC score	0.020516 (rank : 170)	θ value	1.06291 (rank : 79)
Query Neighborhood Hits	173	Target Neighborhood Hits	1058	Shared Neighborhood Hits	47
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

ANR11_HUMAN
NC score	0.020126 (rank : 171)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	173	Target Neighborhood Hits	1289	Shared Neighborhood Hits	51
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

PTCD1_HUMAN
NC score	0.019927 (rank : 172)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	173	Target Neighborhood Hits	52	Shared Neighborhood Hits	12
SwissProt Accessions	O75127, Q66K60, Q9UDV2	Gene names	PTCD1, KIAA0632
Domain Architecture	No domain graphic available
Description	Pentatricopeptide repeat protein 1.

ZN750_HUMAN
NC score	0.019838 (rank : 173)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	173	Target Neighborhood Hits	183	Shared Neighborhood Hits	25
SwissProt Accessions	Q32MQ0, Q9H899	Gene names	ZNF750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

RIMB1_HUMAN
NC score	0.019256 (rank : 174)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	173	Target Neighborhood Hits	1479	Shared Neighborhood Hits	51
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ZEP2_HUMAN
NC score	0.019033 (rank : 175)	θ value	0.62314 (rank : 69)
Query Neighborhood Hits	173	Target Neighborhood Hits	937	Shared Neighborhood Hits	26
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

DACH1_HUMAN
NC score	0.018812 (rank : 176)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	173	Target Neighborhood Hits	214	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UI36, O75523, O75687, Q5VYY3, Q5VYY4, Q96SG3, Q96SG4, Q9H524, Q9UMH4	Gene names	DACH1, DACH
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

PRGC1_HUMAN
NC score	0.018436 (rank : 177)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	173	Target Neighborhood Hits	157	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UBK2, Q9UN32	Gene names	PPARGC1A, LEM6, PGC1, PGC1A, PPARGC1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha) (Ligand effect modulator 6).

SF04_MOUSE
NC score	0.018149 (rank : 178)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	173	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CH02, Q8R094	Gene names	Sf4
Domain Architecture	No domain graphic available
Description	Splicing factor 4.

WNK2_HUMAN
NC score	0.017989 (rank : 179)	θ value	0.62314 (rank : 68)
Query Neighborhood Hits	173	Target Neighborhood Hits	1407	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

EPC1_HUMAN
NC score	0.017891 (rank : 180)	θ value	3.0926 (rank : 95)
Query Neighborhood Hits	173	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H2F5, Q5VW54, Q5VW56, Q5VW58, Q8NAQ4, Q8NE21, Q96LF4, Q96RR6, Q9H7T7	Gene names	EPC1
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 1.

MED12_HUMAN
NC score	0.017612 (rank : 181)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	173	Target Neighborhood Hits	262	Shared Neighborhood Hits	11
SwissProt Accessions	Q93074, O15410, O75557, Q9UHV6, Q9UND7	Gene names	MED12, ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230
Domain Architecture	No domain graphic available
Description	Mediator of RNA polymerase II transcription subunit 12 (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Activator-recruited cofactor 240 kDa component) (ARC240) (CAG repeat protein 45) (OPA-containing protein) (Trinucleotide repeat-containing gene 11 protein).

JUNB_MOUSE
NC score	0.017418 (rank : 182)	θ value	4.03905 (rank : 112)
Query Neighborhood Hits	173	Target Neighborhood Hits	116	Shared Neighborhood Hits	7
SwissProt Accessions	P09450, Q8C2G9	Gene names	Junb, Jun-b
Domain Architecture
Description	Transcription factor jun-B.

DACH1_MOUSE
NC score	0.017304 (rank : 183)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	173	Target Neighborhood Hits	228	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QYB2, O88716, Q8BPQ0, Q8C8D7, Q9QY47, Q9R218, Q9Z0Y5	Gene names	Dach1, Dach
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

PAX9_HUMAN
NC score	0.016799 (rank : 184)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	173	Target Neighborhood Hits	92	Shared Neighborhood Hits	9
SwissProt Accessions	P55771, Q99582, Q9UQR4	Gene names	PAX9
Domain Architecture
Description	Paired box protein Pax-9.

MYST4_HUMAN
NC score	0.016106 (rank : 185)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	173	Target Neighborhood Hits	671	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

SOX13_MOUSE
NC score	0.016066 (rank : 186)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	173	Target Neighborhood Hits	495	Shared Neighborhood Hits	31
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

CECR6_MOUSE
NC score	0.015006 (rank : 187)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	173	Target Neighborhood Hits	22	Shared Neighborhood Hits	7
SwissProt Accessions	Q99MX7	Gene names	Cecr6
Domain Architecture	No domain graphic available
Description	Cat eye syndrome critical region protein 6 homolog.

FOXN1_HUMAN
NC score	0.014493 (rank : 188)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	173	Target Neighborhood Hits	377	Shared Neighborhood Hits	24
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

JUNB_HUMAN
NC score	0.014469 (rank : 189)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	173	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	P17275, Q96GH3	Gene names	JUNB
Domain Architecture
Description	Transcription factor jun-B.

PRDM2_HUMAN
NC score	0.014359 (rank : 190)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	173	Target Neighborhood Hits	1135	Shared Neighborhood Hits	47
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

CD2AP_HUMAN
NC score	0.014046 (rank : 191)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	173	Target Neighborhood Hits	315	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

SPEG_MOUSE
NC score	0.013977 (rank : 192)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	173	Target Neighborhood Hits	1959	Shared Neighborhood Hits	69
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

FOXN1_MOUSE
NC score	0.012745 (rank : 193)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	173	Target Neighborhood Hits	300	Shared Neighborhood Hits	17
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

SPEG_HUMAN
NC score	0.011429 (rank : 194)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	173	Target Neighborhood Hits	1762	Shared Neighborhood Hits	56
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

FOXC1_MOUSE
NC score	0.011260 (rank : 195)	θ value	4.03905 (rank : 110)
Query Neighborhood Hits	173	Target Neighborhood Hits	218	Shared Neighborhood Hits	23
SwissProt Accessions	Q61572, O88409, Q61582	Gene names	Foxc1, Fkh1, Fkhl7, Freac3, Mf1
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3) (Transcription factor FKH-1) (Mesoderm/mesenchyme forkhead 1) (MF-1).

WNK1_HUMAN
NC score	0.010687 (rank : 196)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	173	Target Neighborhood Hits	1158	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

CSPG3_HUMAN
NC score	0.009655 (rank : 197)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	173	Target Neighborhood Hits	676	Shared Neighborhood Hits	32
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

DPOLZ_HUMAN
NC score	0.009179 (rank : 198)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	173	Target Neighborhood Hits	200	Shared Neighborhood Hits	9
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

CD2L7_HUMAN
NC score	0.008013 (rank : 199)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	173	Target Neighborhood Hits	1275	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

TITIN_HUMAN
NC score	0.007609 (rank : 200)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	173	Target Neighborhood Hits	2923	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

MRCKG_HUMAN
NC score	0.006344 (rank : 201)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	173	Target Neighborhood Hits	1519	Shared Neighborhood Hits	28
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

NOTC2_HUMAN
NC score	0.006326 (rank : 202)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	173	Target Neighborhood Hits	1113	Shared Neighborhood Hits	38
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

MK07_MOUSE
NC score	0.005273 (rank : 203)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	173	Target Neighborhood Hits	1054	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

TMPSD_HUMAN
NC score	0.005253 (rank : 204)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	173	Target Neighborhood Hits	333	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

KLF11_MOUSE
NC score	0.003035 (rank : 205)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	173	Target Neighborhood Hits	714	Shared Neighborhood Hits	10
SwissProt Accessions	Q9EPF4	Gene names	Klf11, Tieg2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 11 (Transforming growth factor-beta-inducible early growth response protein 2) (TGFB-inducible early growth response protein 2) (TIEG-2).

KLF11_HUMAN
NC score	0.002931 (rank : 206)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	173	Target Neighborhood Hits	717	Shared Neighborhood Hits	9
SwissProt Accessions	O14901	Gene names	KLF11, FKLF, TIEG2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 11 (Transforming growth factor-beta-inducible early growth response protein 2) (TGFB-inducible early growth response protein 2) (TIEG-2).

COT2_HUMAN
NC score	0.002605 (rank : 207)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	173	Target Neighborhood Hits	135	Shared Neighborhood Hits	5
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT2_MOUSE
NC score	0.002605 (rank : 208)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	173	Target Neighborhood Hits	135	Shared Neighborhood Hits	5
SwissProt Accessions	P43135	Gene names	Nr2f2, Aporp1, Arp-1, Arp1, Tfcoup2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

GSHI_HUMAN
NC score	0.002504 (rank : 209)	θ value	4.03905 (rank : 111)
Query Neighborhood Hits	173	Target Neighborhood Hits	314	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H4S2	Gene names	GSH1
Domain Architecture
Description	Homeobox protein GSH-1.

EGR1_MOUSE
NC score	0.001903 (rank : 210)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	173	Target Neighborhood Hits	816	Shared Neighborhood Hits	24
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

KLF14_HUMAN
NC score	0.000923 (rank : 211)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	173	Target Neighborhood Hits	725	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TD94	Gene names	KLF14, BTEB5
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 14 (Transcription factor BTEB5) (Basic transcription element-binding protein 5) (BTE-binding protein 5).

YSK4_HUMAN
NC score	0.000352 (rank : 212)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	173	Target Neighborhood Hits	921	Shared Neighborhood Hits	14
SwissProt Accessions	Q56UN5, Q56UN1, Q56UN2, Q56UN3, Q56UN4, Q8N4E9, Q9H5T2	Gene names	YSK4, RCK
Domain Architecture	No domain graphic available
Description	SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1) (Regulated in COPD, protein kinase).

ZBT7A_HUMAN
NC score	-0.001835 (rank : 213)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	173	Target Neighborhood Hits	823	Shared Neighborhood Hits	12
SwissProt Accessions	O95365, O00456	Gene names	ZBTB7A, FBI1, LRF, ZBTB7
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma- related factor) (Factor that binds to inducer of short transcripts protein 1) (Factor binding IST protein 1) (FBI-1) (HIV-1 1st-binding protein 1) (TTF-I-interacting peptide 21) (TIP21).