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Network neighborhood for query Sequence : APBB2_HUMAN

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APBB2_HUMAN
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

APBB2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	96	Target Neighborhood Hits	96	Shared Neighborhood Hits	96
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

APBB2_MOUSE
θ value	0 (rank : 2)	NC score	0.987777 (rank : 2)
Query Neighborhood Hits	96	Target Neighborhood Hits	88	Shared Neighborhood Hits	54
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

APBB1_MOUSE
θ value	4.25343e-167 (rank : 3)	NC score	0.950655 (rank : 4)
Query Neighborhood Hits	96	Target Neighborhood Hits	75	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QXJ1, O08642, Q3TPU0, Q8BNF4, Q8BSR9	Gene names	Apbb1, Fe65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

APBB1_HUMAN
θ value	8.86892e-165 (rank : 4)	NC score	0.952235 (rank : 3)
Query Neighborhood Hits	96	Target Neighborhood Hits	62	Shared Neighborhood Hits	27
SwissProt Accessions	O00213, Q96A93	Gene names	APBB1, FE65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

APBB3_HUMAN
θ value	1.48926e-103 (rank : 5)	NC score	0.937955 (rank : 5)
Query Neighborhood Hits	96	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	O95704, Q9NYX6, Q9NYX7, Q9NYX8	Gene names	APBB3, FE65L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2).

APBB3_MOUSE
θ value	6.25694e-102 (rank : 6)	NC score	0.937869 (rank : 6)
Query Neighborhood Hits	96	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R1C9	Gene names	Apbb3
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 3.

WWP2_MOUSE
θ value	1.17247e-07 (rank : 7)	NC score	0.194846 (rank : 7)
Query Neighborhood Hits	96	Target Neighborhood Hits	118	Shared Neighborhood Hits	31
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

WWP1_HUMAN
θ value	0.00035302 (rank : 8)	NC score	0.180191 (rank : 10)
Query Neighborhood Hits	96	Target Neighborhood Hits	262	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

PRG4_MOUSE
θ value	0.00102713 (rank : 9)	NC score	0.046005 (rank : 75)
Query Neighborhood Hits	96	Target Neighborhood Hits	624	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

WWP2_HUMAN
θ value	0.00102713 (rank : 10)	NC score	0.178827 (rank : 11)
Query Neighborhood Hits	96	Target Neighborhood Hits	177	Shared Neighborhood Hits	31
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

ITCH_MOUSE
θ value	0.00509761 (rank : 11)	NC score	0.160470 (rank : 14)
Query Neighborhood Hits	96	Target Neighborhood Hits	127	Shared Neighborhood Hits	28
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

JIP1_HUMAN
θ value	0.00509761 (rank : 12)	NC score	0.120677 (rank : 28)
Query Neighborhood Hits	96	Target Neighborhood Hits	271	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

NEDD4_HUMAN
θ value	0.00509761 (rank : 13)	NC score	0.159203 (rank : 15)
Query Neighborhood Hits	96	Target Neighborhood Hits	214	Shared Neighborhood Hits	31
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

NEDD4_MOUSE
θ value	0.00665767 (rank : 14)	NC score	0.155784 (rank : 17)
Query Neighborhood Hits	96	Target Neighborhood Hits	212	Shared Neighborhood Hits	31
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

ITCH_HUMAN
θ value	0.0113563 (rank : 15)	NC score	0.156570 (rank : 16)
Query Neighborhood Hits	96	Target Neighborhood Hits	162	Shared Neighborhood Hits	30
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

NED4L_HUMAN
θ value	0.0148317 (rank : 16)	NC score	0.153358 (rank : 19)
Query Neighborhood Hits	96	Target Neighborhood Hits	238	Shared Neighborhood Hits	32
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

WWP1_MOUSE
θ value	0.0148317 (rank : 17)	NC score	0.171308 (rank : 12)
Query Neighborhood Hits	96	Target Neighborhood Hits	138	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

MAGI1_HUMAN
θ value	0.0193708 (rank : 18)	NC score	0.082490 (rank : 51)
Query Neighborhood Hits	96	Target Neighborhood Hits	388	Shared Neighborhood Hits	27
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

JIP1_MOUSE
θ value	0.0330416 (rank : 19)	NC score	0.104148 (rank : 34)
Query Neighborhood Hits	96	Target Neighborhood Hits	259	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

NED4L_MOUSE
θ value	0.0431538 (rank : 20)	NC score	0.151277 (rank : 20)
Query Neighborhood Hits	96	Target Neighborhood Hits	231	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NUMBL_HUMAN
θ value	0.0431538 (rank : 21)	NC score	0.101328 (rank : 36)
Query Neighborhood Hits	96	Target Neighborhood Hits	394	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

NUMBL_MOUSE
θ value	0.0431538 (rank : 22)	NC score	0.113264 (rank : 30)
Query Neighborhood Hits	96	Target Neighborhood Hits	147	Shared Neighborhood Hits	17
SwissProt Accessions	O08919, Q6NVG8	Gene names	Numbl, Nbl
Domain Architecture
Description	Numb-like protein.

NUMB_HUMAN
θ value	0.0431538 (rank : 23)	NC score	0.122400 (rank : 27)
Query Neighborhood Hits	96	Target Neighborhood Hits	112	Shared Neighborhood Hits	19
SwissProt Accessions	P49757, Q6NUQ7, Q86SY1, Q8WW73, Q9UBG1, Q9UEQ4, Q9UKE8, Q9UKE9, Q9UKF0, Q9UQJ4	Gene names	NUMB
Domain Architecture
Description	Protein numb homolog (h-Numb) (Protein S171).

NUMB_MOUSE
θ value	0.0431538 (rank : 24)	NC score	0.123184 (rank : 26)
Query Neighborhood Hits	96	Target Neighborhood Hits	91	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QZS3, P70422, Q8CIB1, Q9DC57, Q9QZR1, Q9QZS4	Gene names	Numb
Domain Architecture
Description	Protein numb homolog (m-Numb) (m-Nb).

MAGI1_MOUSE
θ value	0.0563607 (rank : 25)	NC score	0.080961 (rank : 52)
Query Neighborhood Hits	96	Target Neighborhood Hits	403	Shared Neighborhood Hits	27
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

NACAM_MOUSE
θ value	0.0563607 (rank : 26)	NC score	0.043093 (rank : 77)
Query Neighborhood Hits	96	Target Neighborhood Hits	1866	Shared Neighborhood Hits	32
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

GAS7_HUMAN
θ value	0.0961366 (rank : 27)	NC score	0.123466 (rank : 25)
Query Neighborhood Hits	96	Target Neighborhood Hits	258	Shared Neighborhood Hits	25
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

NFM_MOUSE
θ value	0.0961366 (rank : 28)	NC score	0.010756 (rank : 110)
Query Neighborhood Hits	96	Target Neighborhood Hits	1159	Shared Neighborhood Hits	18
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

SETD2_HUMAN
θ value	0.0961366 (rank : 29)	NC score	0.137668 (rank : 21)
Query Neighborhood Hits	96	Target Neighborhood Hits	412	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

ARH_HUMAN
θ value	0.125558 (rank : 30)	NC score	0.125176 (rank : 23)
Query Neighborhood Hits	96	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q5SW96, Q6TQS9, Q8N2Y0, Q9UFI9	Gene names	LDLRAP1, ARH
Domain Architecture	No domain graphic available
Description	Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein).

ZCHC8_MOUSE
θ value	0.163984 (rank : 31)	NC score	0.057487 (rank : 69)
Query Neighborhood Hits	96	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CYA6, Q3TK71, Q8CCB7, Q91WQ1	Gene names	Zcchc8
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 8.

CI079_HUMAN
θ value	0.21417 (rank : 32)	NC score	0.061844 (rank : 64)
Query Neighborhood Hits	96	Target Neighborhood Hits	288	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

SMUF2_HUMAN
θ value	0.21417 (rank : 33)	NC score	0.155735 (rank : 18)
Query Neighborhood Hits	96	Target Neighborhood Hits	142	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

ARH_MOUSE
θ value	0.279714 (rank : 34)	NC score	0.124761 (rank : 24)
Query Neighborhood Hits	96	Target Neighborhood Hits	32	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C142, Q6NWV6, Q8VDQ0	Gene names	Ldlrap1, Arh
Domain Architecture	No domain graphic available
Description	Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein homolog).

PIN1_HUMAN
θ value	0.279714 (rank : 35)	NC score	0.170354 (rank : 13)
Query Neighborhood Hits	96	Target Neighborhood Hits	59	Shared Neighborhood Hits	26
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

PIN1_MOUSE
θ value	0.279714 (rank : 36)	NC score	0.188639 (rank : 9)
Query Neighborhood Hits	96	Target Neighborhood Hits	60	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

STON2_HUMAN
θ value	0.279714 (rank : 37)	NC score	0.040644 (rank : 79)
Query Neighborhood Hits	96	Target Neighborhood Hits	115	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

AP3B1_HUMAN
θ value	0.365318 (rank : 38)	NC score	0.022791 (rank : 88)
Query Neighborhood Hits	96	Target Neighborhood Hits	283	Shared Neighborhood Hits	12
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

GP112_HUMAN
θ value	0.365318 (rank : 39)	NC score	0.019985 (rank : 90)
Query Neighborhood Hits	96	Target Neighborhood Hits	441	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

FILA_HUMAN
θ value	0.47712 (rank : 40)	NC score	0.028667 (rank : 82)
Query Neighborhood Hits	96	Target Neighborhood Hits	685	Shared Neighborhood Hits	17
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

GAS7_MOUSE
θ value	0.47712 (rank : 41)	NC score	0.110570 (rank : 31)
Query Neighborhood Hits	96	Target Neighborhood Hits	259	Shared Neighborhood Hits	26
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

NUCL_HUMAN
θ value	0.47712 (rank : 42)	NC score	0.024902 (rank : 84)
Query Neighborhood Hits	96	Target Neighborhood Hits	415	Shared Neighborhood Hits	9
SwissProt Accessions	P19338, Q53SK1, Q8NB06	Gene names	NCL
Domain Architecture
Description	Nucleolin (Protein C23).

PCLO_HUMAN
θ value	0.47712 (rank : 43)	NC score	0.041568 (rank : 78)
Query Neighborhood Hits	96	Target Neighborhood Hits	2046	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

STON2_MOUSE
θ value	0.47712 (rank : 44)	NC score	0.049956 (rank : 74)
Query Neighborhood Hits	96	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BZ60	Gene names	Ston2, Stn2, Stnb
Domain Architecture
Description	Stonin-2 (Stoned B).

PINL_HUMAN
θ value	0.62314 (rank : 45)	NC score	0.192009 (rank : 8)
Query Neighborhood Hits	96	Target Neighborhood Hits	47	Shared Neighborhood Hits	28
SwissProt Accessions	O15428	Gene names	PIN1L
Domain Architecture
Description	PIN1-like protein.

SMUF1_MOUSE
θ value	0.62314 (rank : 46)	NC score	0.127065 (rank : 22)
Query Neighborhood Hits	96	Target Neighborhood Hits	142	Shared Neighborhood Hits	28
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

ZF106_HUMAN
θ value	0.62314 (rank : 47)	NC score	0.021414 (rank : 89)
Query Neighborhood Hits	96	Target Neighborhood Hits	470	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H2Y7, Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58, Q86TA9, Q96M37, Q9H7B8	Gene names	ZFP106, ZNF474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 homolog (Zfp-106) (Zinc finger protein 474).

ZN507_HUMAN
θ value	1.06291 (rank : 48)	NC score	0.003913 (rank : 125)
Query Neighborhood Hits	96	Target Neighborhood Hits	739	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TCN5	Gene names	ZNF507
Domain Architecture	No domain graphic available
Description	Zinc finger protein 507.

CMGA_HUMAN
θ value	1.38821 (rank : 49)	NC score	0.044304 (rank : 76)
Query Neighborhood Hits	96	Target Neighborhood Hits	238	Shared Neighborhood Hits	13
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

K0056_HUMAN
θ value	1.38821 (rank : 50)	NC score	0.024023 (rank : 86)
Query Neighborhood Hits	96	Target Neighborhood Hits	107	Shared Neighborhood Hits	7
SwissProt Accessions	P42695	Gene names	KIAA0056
Domain Architecture	No domain graphic available
Description	Protein KIAA0056.

MAP1A_HUMAN
θ value	1.38821 (rank : 51)	NC score	0.027450 (rank : 83)
Query Neighborhood Hits	96	Target Neighborhood Hits	1626	Shared Neighborhood Hits	23
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

PCLO_MOUSE
θ value	1.38821 (rank : 52)	NC score	0.036947 (rank : 80)
Query Neighborhood Hits	96	Target Neighborhood Hits	2275	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

CAPON_HUMAN
θ value	1.81305 (rank : 53)	NC score	0.105413 (rank : 33)
Query Neighborhood Hits	96	Target Neighborhood Hits	35	Shared Neighborhood Hits	14
SwissProt Accessions	O75052, O43564	Gene names	NOS1AP, CAPON, KIAA0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).

GNB1L_HUMAN
θ value	1.81305 (rank : 54)	NC score	0.017917 (rank : 91)
Query Neighborhood Hits	96	Target Neighborhood Hits	221	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYB4, Q9H2S2, Q9H4M4	Gene names	GNB1L, GY2, KIAA1645, WDR14
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (WD40 repeat-containing protein deleted in VCFS) (Protein WDVCF) (DGCRK3).

AR13B_MOUSE
θ value	2.36792 (rank : 55)	NC score	0.008777 (rank : 119)
Query Neighborhood Hits	96	Target Neighborhood Hits	245	Shared Neighborhood Hits	3
SwissProt Accessions	Q640N2	Gene names	Arl13b, Arl2l1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

CAPON_MOUSE
θ value	2.36792 (rank : 56)	NC score	0.096002 (rank : 38)
Query Neighborhood Hits	96	Target Neighborhood Hits	34	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D3A8, Q80TZ6	Gene names	Nos1ap, Capon, Kiaa0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).

CBP_MOUSE
θ value	2.36792 (rank : 57)	NC score	0.017889 (rank : 92)
Query Neighborhood Hits	96	Target Neighborhood Hits	1051	Shared Neighborhood Hits	25
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

GP1BA_HUMAN
θ value	2.36792 (rank : 58)	NC score	0.012389 (rank : 106)
Query Neighborhood Hits	96	Target Neighborhood Hits	407	Shared Neighborhood Hits	8
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

TICN3_MOUSE
θ value	2.36792 (rank : 59)	NC score	0.017110 (rank : 95)
Query Neighborhood Hits	96	Target Neighborhood Hits	83	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

TP53B_HUMAN
θ value	2.36792 (rank : 60)	NC score	0.029438 (rank : 81)
Query Neighborhood Hits	96	Target Neighborhood Hits	413	Shared Neighborhood Hits	16
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

PININ_MOUSE
θ value	3.0926 (rank : 61)	NC score	0.014258 (rank : 101)
Query Neighborhood Hits	96	Target Neighborhood Hits	777	Shared Neighborhood Hits	19
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

RN123_HUMAN
θ value	3.0926 (rank : 62)	NC score	0.014437 (rank : 100)
Query Neighborhood Hits	96	Target Neighborhood Hits	175	Shared Neighborhood Hits	3
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

AF9_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.017241 (rank : 94)
Query Neighborhood Hits	96	Target Neighborhood Hits	202	Shared Neighborhood Hits	7
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

CD44_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.024013 (rank : 87)
Query Neighborhood Hits	96	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	P16070, P22511, Q04858, Q13419, Q13957, Q13958, Q13959, Q13960, Q13961, Q13967, Q13968, Q13980, Q15861, Q16064, Q16065, Q16066, Q16208, Q16522, Q96J24	Gene names	CD44, LHR
Domain Architecture
Description	CD44 antigen precursor (Phagocytic glycoprotein I) (PGP-1) (HUTCH-I) (Extracellular matrix receptor-III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (Hermes antigen) (Hyaluronate receptor) (Heparan sulfate proteoglycan) (Epican) (CDw44).

ES8L2_MOUSE
θ value	4.03905 (rank : 65)	NC score	0.011849 (rank : 107)
Query Neighborhood Hits	96	Target Neighborhood Hits	169	Shared Neighborhood Hits	4
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

HIPK2_HUMAN
θ value	4.03905 (rank : 66)	NC score	-0.000306 (rank : 129)
Query Neighborhood Hits	96	Target Neighborhood Hits	845	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H2X6, Q75MR7, Q8WWI4, Q9H2Y1	Gene names	HIPK2
Domain Architecture
Description	Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (hHIPk2).

NFAC3_HUMAN
θ value	4.03905 (rank : 67)	NC score	0.010453 (rank : 112)
Query Neighborhood Hits	96	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	Q12968, O75211, Q14516, Q99840, Q99841, Q99842	Gene names	NFATC3, NFAT4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

NFH_MOUSE
θ value	4.03905 (rank : 68)	NC score	0.013926 (rank : 103)
Query Neighborhood Hits	96	Target Neighborhood Hits	2247	Shared Neighborhood Hits	33
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RRBP1_MOUSE
θ value	4.03905 (rank : 69)	NC score	0.006756 (rank : 123)
Query Neighborhood Hits	96	Target Neighborhood Hits	1650	Shared Neighborhood Hits	21
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

THYG_MOUSE
θ value	4.03905 (rank : 70)	NC score	0.012860 (rank : 105)
Query Neighborhood Hits	96	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

WRN_MOUSE
θ value	4.03905 (rank : 71)	NC score	0.009976 (rank : 113)
Query Neighborhood Hits	96	Target Neighborhood Hits	295	Shared Neighborhood Hits	5
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

ZN318_MOUSE
θ value	4.03905 (rank : 72)	NC score	0.016726 (rank : 96)
Query Neighborhood Hits	96	Target Neighborhood Hits	642	Shared Neighborhood Hits	14
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

ZN451_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.009080 (rank : 116)
Query Neighborhood Hits	96	Target Neighborhood Hits	643	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C0P7	Gene names	Znf451, Zfp451
Domain Architecture	No domain graphic available
Description	Zinc finger protein 451.

NKTR_MOUSE
θ value	5.27518 (rank : 74)	NC score	0.009912 (rank : 114)
Query Neighborhood Hits	96	Target Neighborhood Hits	417	Shared Neighborhood Hits	13
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

RIMS2_HUMAN
θ value	5.27518 (rank : 75)	NC score	0.024637 (rank : 85)
Query Neighborhood Hits	96	Target Neighborhood Hits	342	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

SEMG2_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.015855 (rank : 97)
Query Neighborhood Hits	96	Target Neighborhood Hits	251	Shared Neighborhood Hits	8
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

SOX9_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.014526 (rank : 99)
Query Neighborhood Hits	96	Target Neighborhood Hits	210	Shared Neighborhood Hits	10
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

K0408_HUMAN
θ value	6.88961 (rank : 78)	NC score	0.017297 (rank : 93)
Query Neighborhood Hits	96	Target Neighborhood Hits	101	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZU52, O43158, Q5TF20, Q7L2M2	Gene names	KIAA0408
Domain Architecture	No domain graphic available
Description	Protein KIAA0408.

PRLR_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.008659 (rank : 120)
Query Neighborhood Hits	96	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	P16471, Q16354, Q9BX87	Gene names	PRLR
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

SYNJ1_MOUSE
θ value	6.88961 (rank : 80)	NC score	0.015246 (rank : 98)
Query Neighborhood Hits	96	Target Neighborhood Hits	516	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TAI12_HUMAN
θ value	6.88961 (rank : 81)	NC score	0.008909 (rank : 118)
Query Neighborhood Hits	96	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H175	Gene names	TAIP12, C12orf22
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 12 (TAIP-12).

TICN3_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.014121 (rank : 102)
Query Neighborhood Hits	96	Target Neighborhood Hits	82	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

ANK3_HUMAN
θ value	8.99809 (rank : 83)	NC score	0.003357 (rank : 128)
Query Neighborhood Hits	96	Target Neighborhood Hits	853	Shared Neighborhood Hits	23
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

CO5A2_HUMAN
θ value	8.99809 (rank : 84)	NC score	0.003631 (rank : 127)
Query Neighborhood Hits	96	Target Neighborhood Hits	760	Shared Neighborhood Hits	11
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

ES8L2_HUMAN
θ value	8.99809 (rank : 85)	NC score	0.010640 (rank : 111)
Query Neighborhood Hits	96	Target Neighborhood Hits	193	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9	Gene names	EPS8L2, EPS8R2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

FA13A_HUMAN
θ value	8.99809 (rank : 86)	NC score	0.007736 (rank : 121)
Query Neighborhood Hits	96	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

HTF4_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.005919 (rank : 124)
Query Neighborhood Hits	96	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

ISK5_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.013165 (rank : 104)
Query Neighborhood Hits	96	Target Neighborhood Hits	89	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NQ38, O75770, Q96PP2, Q96PP3	Gene names	SPINK5
Domain Architecture
Description	Serine protease inhibitor Kazal-type 5 precursor (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Contains: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665].

MNAB_MOUSE
θ value	8.99809 (rank : 89)	NC score	0.009078 (rank : 117)
Query Neighborhood Hits	96	Target Neighborhood Hits	231	Shared Neighborhood Hits	9
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

PTPRZ_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.003873 (rank : 126)
Query Neighborhood Hits	96	Target Neighborhood Hits	255	Shared Neighborhood Hits	7
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

PYGO1_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.009866 (rank : 115)
Query Neighborhood Hits	96	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y3Y4	Gene names	PYGO1
Domain Architecture
Description	Pygopus homolog 1.

RERE_HUMAN
θ value	8.99809 (rank : 92)	NC score	0.011753 (rank : 108)
Query Neighborhood Hits	96	Target Neighborhood Hits	779	Shared Neighborhood Hits	23
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

TIF1G_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.006885 (rank : 122)
Query Neighborhood Hits	96	Target Neighborhood Hits	410	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

WWOX_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.071287 (rank : 55)
Query Neighborhood Hits	96	Target Neighborhood Hits	115	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZC7, Q5MYT5, Q96KM3, Q96RF2, Q9BTT8, Q9NPC9, Q9NRF4, Q9NRF5, Q9NRF6, Q9NRK1, Q9NZC5	Gene names	WWOX, FOR, WOX1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase).

WWOX_MOUSE
θ value	8.99809 (rank : 95)	NC score	0.070644 (rank : 56)
Query Neighborhood Hits	96	Target Neighborhood Hits	118	Shared Neighborhood Hits	23
SwissProt Accessions	Q91WL8, Q8C8J6, Q920Y2, Q9D2B3, Q9D339, Q9JLF5	Gene names	Wwox, Wox1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-).

ZN346_MOUSE
θ value	8.99809 (rank : 96)	NC score	0.010928 (rank : 109)
Query Neighborhood Hits	96	Target Neighborhood Hits	93	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R0B7	Gene names	Znf346, Jaz, Zfp346
Domain Architecture	No domain graphic available
Description	Zinc finger protein 346 (Just another zinc finger protein).

BAG3_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.061917 (rank : 63)
Query Neighborhood Hits	96	Target Neighborhood Hits	314	Shared Neighborhood Hits	29
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

BAG3_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.055705 (rank : 73)
Query Neighborhood Hits	96	Target Neighborhood Hits	513	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

EDD1_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.061983 (rank : 62)
Query Neighborhood Hits	96	Target Neighborhood Hits	170	Shared Neighborhood Hits	16
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

EDD1_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.061752 (rank : 65)
Query Neighborhood Hits	96	Target Neighborhood Hits	167	Shared Neighborhood Hits	16
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

HECD1_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.056668 (rank : 72)
Query Neighborhood Hits	96	Target Neighborhood Hits	371	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

HECD2_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.090397 (rank : 44)
Query Neighborhood Hits	96	Target Neighborhood Hits	41	Shared Neighborhood Hits	12
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HECD2_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.091084 (rank : 43)
Query Neighborhood Hits	96	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CDU6, Q8CBQ9	Gene names	Hectd2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HECD3_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.062408 (rank : 61)
Query Neighborhood Hits	96	Target Neighborhood Hits	49	Shared Neighborhood Hits	12
SwissProt Accessions	Q5T447, Q5T448, Q9H783	Gene names	HECTD3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HECD3_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.063513 (rank : 60)
Query Neighborhood Hits	96	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	Q3U487, Q3TN76, Q641P3, Q8BQ74, Q8R1L6	Gene names	Hectd3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HERC2_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.058796 (rank : 68)
Query Neighborhood Hits	96	Target Neighborhood Hits	163	Shared Neighborhood Hits	15
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC2_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.059569 (rank : 67)
Query Neighborhood Hits	96	Target Neighborhood Hits	167	Shared Neighborhood Hits	14
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC3_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.073186 (rank : 54)
Query Neighborhood Hits	96	Target Neighborhood Hits	62	Shared Neighborhood Hits	12
SwissProt Accessions	Q15034	Gene names	HERC3, KIAA0032
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain protein 3.

HERC5_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.074904 (rank : 53)
Query Neighborhood Hits	96	Target Neighborhood Hits	66	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UII4	Gene names	HERC5, CEB1, CEBP1
Domain Architecture
Description	HECT domain and RCC1-like domain-containing protein 5 (Cyclin-E- binding protein 1).

HUWE1_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.093857 (rank : 42)
Query Neighborhood Hits	96	Target Neighborhood Hits	443	Shared Neighborhood Hits	21
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.102687 (rank : 35)
Query Neighborhood Hits	96	Target Neighborhood Hits	406	Shared Neighborhood Hits	23
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

K0317_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.095297 (rank : 39)
Query Neighborhood Hits	96	Target Neighborhood Hits	46	Shared Neighborhood Hits	12
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K0317_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.095206 (rank : 40)
Query Neighborhood Hits	96	Target Neighborhood Hits	43	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CHG5, Q6P9Q1, Q80YC4, Q8C5W5	Gene names	Kiaa0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

MAGI2_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.057139 (rank : 71)
Query Neighborhood Hits	96	Target Neighborhood Hits	373	Shared Neighborhood Hits	24
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI2_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.060820 (rank : 66)
Query Neighborhood Hits	96	Target Neighborhood Hits	370	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

SAV1_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.098206 (rank : 37)
Query Neighborhood Hits	96	Target Neighborhood Hits	51	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

SAV1_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.094256 (rank : 41)
Query Neighborhood Hits	96	Target Neighborhood Hits	48	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VEB2, Q9D9N9, Q9ER46	Gene names	Sav1, Ww45, Wwp3
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (mWW45).

SMUF1_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.115063 (rank : 29)
Query Neighborhood Hits	96	Target Neighborhood Hits	135	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

TRIPC_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.084564 (rank : 50)
Query Neighborhood Hits	96	Target Neighborhood Hits	319	Shared Neighborhood Hits	20
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

UBE3A_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.088161 (rank : 46)
Query Neighborhood Hits	96	Target Neighborhood Hits	49	Shared Neighborhood Hits	12
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

UBE3A_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.087099 (rank : 47)
Query Neighborhood Hits	96	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	O08759, P97482	Gene names	Ube3a
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic protein- associated protein E6-AP).

UBE3C_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.086804 (rank : 48)
Query Neighborhood Hits	96	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

UBE3C_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.086488 (rank : 49)
Query Neighborhood Hits	96	Target Neighborhood Hits	48	Shared Neighborhood Hits	12
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

WWC1_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.069150 (rank : 57)
Query Neighborhood Hits	96	Target Neighborhood Hits	290	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

WWC1_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.068695 (rank : 58)
Query Neighborhood Hits	96	Target Neighborhood Hits	290	Shared Neighborhood Hits	19
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

WWTR1_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.068537 (rank : 59)
Query Neighborhood Hits	96	Target Neighborhood Hits	76	Shared Neighborhood Hits	25
SwissProt Accessions	Q9GZV5, Q8N3P2, Q9Y3W6	Gene names	WWTR1, TAZ
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

WWTR1_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.057252 (rank : 70)
Query Neighborhood Hits	96	Target Neighborhood Hits	54	Shared Neighborhood Hits	21
SwissProt Accessions	Q9EPK5, Q99KI4	Gene names	Wwtr1, Taz
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

YAP1_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.089533 (rank : 45)
Query Neighborhood Hits	96	Target Neighborhood Hits	173	Shared Neighborhood Hits	29
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

YAP1_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.108200 (rank : 32)
Query Neighborhood Hits	96	Target Neighborhood Hits	96	Shared Neighborhood Hits	27
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

Hits sorted by NC score

APBB2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	96	Target Neighborhood Hits	96	Shared Neighborhood Hits	96
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

APBB2_MOUSE
NC score	0.987777 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	96	Target Neighborhood Hits	88	Shared Neighborhood Hits	54
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

APBB1_HUMAN
NC score	0.952235 (rank : 3)	θ value	8.86892e-165 (rank : 4)
Query Neighborhood Hits	96	Target Neighborhood Hits	62	Shared Neighborhood Hits	27
SwissProt Accessions	O00213, Q96A93	Gene names	APBB1, FE65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

APBB1_MOUSE
NC score	0.950655 (rank : 4)	θ value	4.25343e-167 (rank : 3)
Query Neighborhood Hits	96	Target Neighborhood Hits	75	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QXJ1, O08642, Q3TPU0, Q8BNF4, Q8BSR9	Gene names	Apbb1, Fe65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

APBB3_HUMAN
NC score	0.937955 (rank : 5)	θ value	1.48926e-103 (rank : 5)
Query Neighborhood Hits	96	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	O95704, Q9NYX6, Q9NYX7, Q9NYX8	Gene names	APBB3, FE65L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2).

APBB3_MOUSE
NC score	0.937869 (rank : 6)	θ value	6.25694e-102 (rank : 6)
Query Neighborhood Hits	96	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R1C9	Gene names	Apbb3
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 3.

WWP2_MOUSE
NC score	0.194846 (rank : 7)	θ value	1.17247e-07 (rank : 7)
Query Neighborhood Hits	96	Target Neighborhood Hits	118	Shared Neighborhood Hits	31
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

PINL_HUMAN
NC score	0.192009 (rank : 8)	θ value	0.62314 (rank : 45)
Query Neighborhood Hits	96	Target Neighborhood Hits	47	Shared Neighborhood Hits	28
SwissProt Accessions	O15428	Gene names	PIN1L
Domain Architecture
Description	PIN1-like protein.

PIN1_MOUSE
NC score	0.188639 (rank : 9)	θ value	0.279714 (rank : 36)
Query Neighborhood Hits	96	Target Neighborhood Hits	60	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

WWP1_HUMAN
NC score	0.180191 (rank : 10)	θ value	0.00035302 (rank : 8)
Query Neighborhood Hits	96	Target Neighborhood Hits	262	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

WWP2_HUMAN
NC score	0.178827 (rank : 11)	θ value	0.00102713 (rank : 10)
Query Neighborhood Hits	96	Target Neighborhood Hits	177	Shared Neighborhood Hits	31
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

WWP1_MOUSE
NC score	0.171308 (rank : 12)	θ value	0.0148317 (rank : 17)
Query Neighborhood Hits	96	Target Neighborhood Hits	138	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

PIN1_HUMAN
NC score	0.170354 (rank : 13)	θ value	0.279714 (rank : 35)
Query Neighborhood Hits	96	Target Neighborhood Hits	59	Shared Neighborhood Hits	26
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

ITCH_MOUSE
NC score	0.160470 (rank : 14)	θ value	0.00509761 (rank : 11)
Query Neighborhood Hits	96	Target Neighborhood Hits	127	Shared Neighborhood Hits	28
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

NEDD4_HUMAN
NC score	0.159203 (rank : 15)	θ value	0.00509761 (rank : 13)
Query Neighborhood Hits	96	Target Neighborhood Hits	214	Shared Neighborhood Hits	31
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

ITCH_HUMAN
NC score	0.156570 (rank : 16)	θ value	0.0113563 (rank : 15)
Query Neighborhood Hits	96	Target Neighborhood Hits	162	Shared Neighborhood Hits	30
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

NEDD4_MOUSE
NC score	0.155784 (rank : 17)	θ value	0.00665767 (rank : 14)
Query Neighborhood Hits	96	Target Neighborhood Hits	212	Shared Neighborhood Hits	31
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

SMUF2_HUMAN
NC score	0.155735 (rank : 18)	θ value	0.21417 (rank : 33)
Query Neighborhood Hits	96	Target Neighborhood Hits	142	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

NED4L_HUMAN
NC score	0.153358 (rank : 19)	θ value	0.0148317 (rank : 16)
Query Neighborhood Hits	96	Target Neighborhood Hits	238	Shared Neighborhood Hits	32
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_MOUSE
NC score	0.151277 (rank : 20)	θ value	0.0431538 (rank : 20)
Query Neighborhood Hits	96	Target Neighborhood Hits	231	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

SETD2_HUMAN
NC score	0.137668 (rank : 21)	θ value	0.0961366 (rank : 29)
Query Neighborhood Hits	96	Target Neighborhood Hits	412	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SMUF1_MOUSE
NC score	0.127065 (rank : 22)	θ value	0.62314 (rank : 46)
Query Neighborhood Hits	96	Target Neighborhood Hits	142	Shared Neighborhood Hits	28
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

ARH_HUMAN
NC score	0.125176 (rank : 23)	θ value	0.125558 (rank : 30)
Query Neighborhood Hits	96	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q5SW96, Q6TQS9, Q8N2Y0, Q9UFI9	Gene names	LDLRAP1, ARH
Domain Architecture	No domain graphic available
Description	Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein).

ARH_MOUSE
NC score	0.124761 (rank : 24)	θ value	0.279714 (rank : 34)
Query Neighborhood Hits	96	Target Neighborhood Hits	32	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C142, Q6NWV6, Q8VDQ0	Gene names	Ldlrap1, Arh
Domain Architecture	No domain graphic available
Description	Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein homolog).

GAS7_HUMAN
NC score	0.123466 (rank : 25)	θ value	0.0961366 (rank : 27)
Query Neighborhood Hits	96	Target Neighborhood Hits	258	Shared Neighborhood Hits	25
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

NUMB_MOUSE
NC score	0.123184 (rank : 26)	θ value	0.0431538 (rank : 24)
Query Neighborhood Hits	96	Target Neighborhood Hits	91	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QZS3, P70422, Q8CIB1, Q9DC57, Q9QZR1, Q9QZS4	Gene names	Numb
Domain Architecture
Description	Protein numb homolog (m-Numb) (m-Nb).

NUMB_HUMAN
NC score	0.122400 (rank : 27)	θ value	0.0431538 (rank : 23)
Query Neighborhood Hits	96	Target Neighborhood Hits	112	Shared Neighborhood Hits	19
SwissProt Accessions	P49757, Q6NUQ7, Q86SY1, Q8WW73, Q9UBG1, Q9UEQ4, Q9UKE8, Q9UKE9, Q9UKF0, Q9UQJ4	Gene names	NUMB
Domain Architecture
Description	Protein numb homolog (h-Numb) (Protein S171).

JIP1_HUMAN
NC score	0.120677 (rank : 28)	θ value	0.00509761 (rank : 12)
Query Neighborhood Hits	96	Target Neighborhood Hits	271	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

SMUF1_HUMAN
NC score	0.115063 (rank : 29)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	96	Target Neighborhood Hits	135	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

NUMBL_MOUSE
NC score	0.113264 (rank : 30)	θ value	0.0431538 (rank : 22)
Query Neighborhood Hits	96	Target Neighborhood Hits	147	Shared Neighborhood Hits	17
SwissProt Accessions	O08919, Q6NVG8	Gene names	Numbl, Nbl
Domain Architecture
Description	Numb-like protein.

GAS7_MOUSE
NC score	0.110570 (rank : 31)	θ value	0.47712 (rank : 41)
Query Neighborhood Hits	96	Target Neighborhood Hits	259	Shared Neighborhood Hits	26
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

YAP1_MOUSE
NC score	0.108200 (rank : 32)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	96	Target Neighborhood Hits	96	Shared Neighborhood Hits	27
SwissProt Accessions	P46938, Q52KJ5	Gene names	Yap1, Yap, Yap65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

CAPON_HUMAN
NC score	0.105413 (rank : 33)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	96	Target Neighborhood Hits	35	Shared Neighborhood Hits	14
SwissProt Accessions	O75052, O43564	Gene names	NOS1AP, CAPON, KIAA0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).

JIP1_MOUSE
NC score	0.104148 (rank : 34)	θ value	0.0330416 (rank : 19)
Query Neighborhood Hits	96	Target Neighborhood Hits	259	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

HUWE1_MOUSE
NC score	0.102687 (rank : 35)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	96	Target Neighborhood Hits	406	Shared Neighborhood Hits	23
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

NUMBL_HUMAN
NC score	0.101328 (rank : 36)	θ value	0.0431538 (rank : 21)
Query Neighborhood Hits	96	Target Neighborhood Hits	394	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

SAV1_HUMAN
NC score	0.098206 (rank : 37)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	96	Target Neighborhood Hits	51	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H4B6, Q6IA58, Q9H949, Q9HAK9	Gene names	SAV1, WW45
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (hWW45).

CAPON_MOUSE
NC score	0.096002 (rank : 38)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	96	Target Neighborhood Hits	34	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D3A8, Q80TZ6	Gene names	Nos1ap, Capon, Kiaa0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).

K0317_HUMAN
NC score	0.095297 (rank : 39)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	96	Target Neighborhood Hits	46	Shared Neighborhood Hits	12
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K0317_MOUSE
NC score	0.095206 (rank : 40)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	96	Target Neighborhood Hits	43	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CHG5, Q6P9Q1, Q80YC4, Q8C5W5	Gene names	Kiaa0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

SAV1_MOUSE
NC score	0.094256 (rank : 41)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	96	Target Neighborhood Hits	48	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VEB2, Q9D9N9, Q9ER46	Gene names	Sav1, Ww45, Wwp3
Domain Architecture
Description	Salvador homolog 1 protein (45 kDa WW domain protein) (mWW45).

HUWE1_HUMAN
NC score	0.093857 (rank : 42)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	96	Target Neighborhood Hits	443	Shared Neighborhood Hits	21
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HECD2_MOUSE
NC score	0.091084 (rank : 43)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	96	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CDU6, Q8CBQ9	Gene names	Hectd2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

HECD2_HUMAN
NC score	0.090397 (rank : 44)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	96	Target Neighborhood Hits	41	Shared Neighborhood Hits	12
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

YAP1_HUMAN
NC score	0.089533 (rank : 45)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	96	Target Neighborhood Hits	173	Shared Neighborhood Hits	29
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

UBE3A_HUMAN
NC score	0.088161 (rank : 46)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	96	Target Neighborhood Hits	49	Shared Neighborhood Hits	12
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

UBE3A_MOUSE
NC score	0.087099 (rank : 47)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	96	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	O08759, P97482	Gene names	Ube3a
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic protein- associated protein E6-AP).

UBE3C_HUMAN
NC score	0.086804 (rank : 48)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	96	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

UBE3C_MOUSE
NC score	0.086488 (rank : 49)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	96	Target Neighborhood Hits	48	Shared Neighborhood Hits	12
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

TRIPC_HUMAN
NC score	0.084564 (rank : 50)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	96	Target Neighborhood Hits	319	Shared Neighborhood Hits	20
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

MAGI1_HUMAN
NC score	0.082490 (rank : 51)	θ value	0.0193708 (rank : 18)
Query Neighborhood Hits	96	Target Neighborhood Hits	388	Shared Neighborhood Hits	27
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

MAGI1_MOUSE
NC score	0.080961 (rank : 52)	θ value	0.0563607 (rank : 25)
Query Neighborhood Hits	96	Target Neighborhood Hits	403	Shared Neighborhood Hits	27
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

HERC5_HUMAN
NC score	0.074904 (rank : 53)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	96	Target Neighborhood Hits	66	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UII4	Gene names	HERC5, CEB1, CEBP1
Domain Architecture
Description	HECT domain and RCC1-like domain-containing protein 5 (Cyclin-E- binding protein 1).

HERC3_HUMAN
NC score	0.073186 (rank : 54)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	96	Target Neighborhood Hits	62	Shared Neighborhood Hits	12
SwissProt Accessions	Q15034	Gene names	HERC3, KIAA0032
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain protein 3.

WWOX_HUMAN
NC score	0.071287 (rank : 55)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	96	Target Neighborhood Hits	115	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZC7, Q5MYT5, Q96KM3, Q96RF2, Q9BTT8, Q9NPC9, Q9NRF4, Q9NRF5, Q9NRF6, Q9NRK1, Q9NZC5	Gene names	WWOX, FOR, WOX1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase).

WWOX_MOUSE
NC score	0.070644 (rank : 56)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	96	Target Neighborhood Hits	118	Shared Neighborhood Hits	23
SwissProt Accessions	Q91WL8, Q8C8J6, Q920Y2, Q9D2B3, Q9D339, Q9JLF5	Gene names	Wwox, Wox1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-).

WWC1_HUMAN
NC score	0.069150 (rank : 57)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	96	Target Neighborhood Hits	290	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

WWC1_MOUSE
NC score	0.068695 (rank : 58)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	96	Target Neighborhood Hits	290	Shared Neighborhood Hits	19
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

WWTR1_HUMAN
NC score	0.068537 (rank : 59)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	96	Target Neighborhood Hits	76	Shared Neighborhood Hits	25
SwissProt Accessions	Q9GZV5, Q8N3P2, Q9Y3W6	Gene names	WWTR1, TAZ
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

HECD3_MOUSE
NC score	0.063513 (rank : 60)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	96	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	Q3U487, Q3TN76, Q641P3, Q8BQ74, Q8R1L6	Gene names	Hectd3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

HECD3_HUMAN
NC score	0.062408 (rank : 61)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	96	Target Neighborhood Hits	49	Shared Neighborhood Hits	12
SwissProt Accessions	Q5T447, Q5T448, Q9H783	Gene names	HECTD3
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD3 (HECT domain-containing protein 3).

EDD1_HUMAN
NC score	0.061983 (rank : 62)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	96	Target Neighborhood Hits	170	Shared Neighborhood Hits	16
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

BAG3_HUMAN
NC score	0.061917 (rank : 63)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	96	Target Neighborhood Hits	314	Shared Neighborhood Hits	29
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

CI079_HUMAN
NC score	0.061844 (rank : 64)	θ value	0.21417 (rank : 32)
Query Neighborhood Hits	96	Target Neighborhood Hits	288	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

EDD1_MOUSE
NC score	0.061752 (rank : 65)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	96	Target Neighborhood Hits	167	Shared Neighborhood Hits	16
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

MAGI2_MOUSE
NC score	0.060820 (rank : 66)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	96	Target Neighborhood Hits	370	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

HERC2_MOUSE
NC score	0.059569 (rank : 67)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	96	Target Neighborhood Hits	167	Shared Neighborhood Hits	14
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC2_HUMAN
NC score	0.058796 (rank : 68)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	96	Target Neighborhood Hits	163	Shared Neighborhood Hits	15
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

ZCHC8_MOUSE
NC score	0.057487 (rank : 69)	θ value	0.163984 (rank : 31)
Query Neighborhood Hits	96	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CYA6, Q3TK71, Q8CCB7, Q91WQ1	Gene names	Zcchc8
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 8.

WWTR1_MOUSE
NC score	0.057252 (rank : 70)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	96	Target Neighborhood Hits	54	Shared Neighborhood Hits	21
SwissProt Accessions	Q9EPK5, Q99KI4	Gene names	Wwtr1, Taz
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

MAGI2_HUMAN
NC score	0.057139 (rank : 71)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	96	Target Neighborhood Hits	373	Shared Neighborhood Hits	24
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

HECD1_HUMAN
NC score	0.056668 (rank : 72)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	96	Target Neighborhood Hits	371	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

BAG3_MOUSE
NC score	0.055705 (rank : 73)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	96	Target Neighborhood Hits	513	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

STON2_MOUSE
NC score	0.049956 (rank : 74)	θ value	0.47712 (rank : 44)
Query Neighborhood Hits	96	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BZ60	Gene names	Ston2, Stn2, Stnb
Domain Architecture
Description	Stonin-2 (Stoned B).

PRG4_MOUSE
NC score	0.046005 (rank : 75)	θ value	0.00102713 (rank : 9)
Query Neighborhood Hits	96	Target Neighborhood Hits	624	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

CMGA_HUMAN
NC score	0.044304 (rank : 76)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	96	Target Neighborhood Hits	238	Shared Neighborhood Hits	13
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

NACAM_MOUSE
NC score	0.043093 (rank : 77)	θ value	0.0563607 (rank : 26)
Query Neighborhood Hits	96	Target Neighborhood Hits	1866	Shared Neighborhood Hits	32
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PCLO_HUMAN
NC score	0.041568 (rank : 78)	θ value	0.47712 (rank : 43)
Query Neighborhood Hits	96	Target Neighborhood Hits	2046	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

STON2_HUMAN
NC score	0.040644 (rank : 79)	θ value	0.279714 (rank : 37)
Query Neighborhood Hits	96	Target Neighborhood Hits	115	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

PCLO_MOUSE
NC score	0.036947 (rank : 80)	θ value	1.38821 (rank : 52)
Query Neighborhood Hits	96	Target Neighborhood Hits	2275	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

TP53B_HUMAN
NC score	0.029438 (rank : 81)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	96	Target Neighborhood Hits	413	Shared Neighborhood Hits	16
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

FILA_HUMAN
NC score	0.028667 (rank : 82)	θ value	0.47712 (rank : 40)
Query Neighborhood Hits	96	Target Neighborhood Hits	685	Shared Neighborhood Hits	17
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

MAP1A_HUMAN
NC score	0.027450 (rank : 83)	θ value	1.38821 (rank : 51)
Query Neighborhood Hits	96	Target Neighborhood Hits	1626	Shared Neighborhood Hits	23
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

NUCL_HUMAN
NC score	0.024902 (rank : 84)	θ value	0.47712 (rank : 42)
Query Neighborhood Hits	96	Target Neighborhood Hits	415	Shared Neighborhood Hits	9
SwissProt Accessions	P19338, Q53SK1, Q8NB06	Gene names	NCL
Domain Architecture
Description	Nucleolin (Protein C23).

RIMS2_HUMAN
NC score	0.024637 (rank : 85)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	96	Target Neighborhood Hits	342	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

K0056_HUMAN
NC score	0.024023 (rank : 86)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	96	Target Neighborhood Hits	107	Shared Neighborhood Hits	7
SwissProt Accessions	P42695	Gene names	KIAA0056
Domain Architecture	No domain graphic available
Description	Protein KIAA0056.

CD44_HUMAN
NC score	0.024013 (rank : 87)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	96	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	P16070, P22511, Q04858, Q13419, Q13957, Q13958, Q13959, Q13960, Q13961, Q13967, Q13968, Q13980, Q15861, Q16064, Q16065, Q16066, Q16208, Q16522, Q96J24	Gene names	CD44, LHR
Domain Architecture
Description	CD44 antigen precursor (Phagocytic glycoprotein I) (PGP-1) (HUTCH-I) (Extracellular matrix receptor-III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (Hermes antigen) (Hyaluronate receptor) (Heparan sulfate proteoglycan) (Epican) (CDw44).

AP3B1_HUMAN
NC score	0.022791 (rank : 88)	θ value	0.365318 (rank : 38)
Query Neighborhood Hits	96	Target Neighborhood Hits	283	Shared Neighborhood Hits	12
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

ZF106_HUMAN
NC score	0.021414 (rank : 89)	θ value	0.62314 (rank : 47)
Query Neighborhood Hits	96	Target Neighborhood Hits	470	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H2Y7, Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58, Q86TA9, Q96M37, Q9H7B8	Gene names	ZFP106, ZNF474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 homolog (Zfp-106) (Zinc finger protein 474).

GP112_HUMAN
NC score	0.019985 (rank : 90)	θ value	0.365318 (rank : 39)
Query Neighborhood Hits	96	Target Neighborhood Hits	441	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

GNB1L_HUMAN
NC score	0.017917 (rank : 91)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	96	Target Neighborhood Hits	221	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYB4, Q9H2S2, Q9H4M4	Gene names	GNB1L, GY2, KIAA1645, WDR14
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (WD40 repeat-containing protein deleted in VCFS) (Protein WDVCF) (DGCRK3).

CBP_MOUSE
NC score	0.017889 (rank : 92)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	96	Target Neighborhood Hits	1051	Shared Neighborhood Hits	25
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

K0408_HUMAN
NC score	0.017297 (rank : 93)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	96	Target Neighborhood Hits	101	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZU52, O43158, Q5TF20, Q7L2M2	Gene names	KIAA0408
Domain Architecture	No domain graphic available
Description	Protein KIAA0408.

AF9_HUMAN
NC score	0.017241 (rank : 94)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	96	Target Neighborhood Hits	202	Shared Neighborhood Hits	7
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

TICN3_MOUSE
NC score	0.017110 (rank : 95)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	96	Target Neighborhood Hits	83	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

ZN318_MOUSE
NC score	0.016726 (rank : 96)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	96	Target Neighborhood Hits	642	Shared Neighborhood Hits	14
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

SEMG2_HUMAN
NC score	0.015855 (rank : 97)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	96	Target Neighborhood Hits	251	Shared Neighborhood Hits	8
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

SYNJ1_MOUSE
NC score	0.015246 (rank : 98)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	96	Target Neighborhood Hits	516	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SOX9_HUMAN
NC score	0.014526 (rank : 99)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	96	Target Neighborhood Hits	210	Shared Neighborhood Hits	10
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

RN123_HUMAN
NC score	0.014437 (rank : 100)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	96	Target Neighborhood Hits	175	Shared Neighborhood Hits	3
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

PININ_MOUSE
NC score	0.014258 (rank : 101)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	96	Target Neighborhood Hits	777	Shared Neighborhood Hits	19
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

TICN3_HUMAN
NC score	0.014121 (rank : 102)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	96	Target Neighborhood Hits	82	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

NFH_MOUSE
NC score	0.013926 (rank : 103)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	96	Target Neighborhood Hits	2247	Shared Neighborhood Hits	33
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ISK5_HUMAN
NC score	0.013165 (rank : 104)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	96	Target Neighborhood Hits	89	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NQ38, O75770, Q96PP2, Q96PP3	Gene names	SPINK5
Domain Architecture
Description	Serine protease inhibitor Kazal-type 5 precursor (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Contains: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665].

THYG_MOUSE
NC score	0.012860 (rank : 105)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	96	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

GP1BA_HUMAN
NC score	0.012389 (rank : 106)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	96	Target Neighborhood Hits	407	Shared Neighborhood Hits	8
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

ES8L2_MOUSE
NC score	0.011849 (rank : 107)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	96	Target Neighborhood Hits	169	Shared Neighborhood Hits	4
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

RERE_HUMAN
NC score	0.011753 (rank : 108)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	96	Target Neighborhood Hits	779	Shared Neighborhood Hits	23
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

ZN346_MOUSE
NC score	0.010928 (rank : 109)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	96	Target Neighborhood Hits	93	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R0B7	Gene names	Znf346, Jaz, Zfp346
Domain Architecture	No domain graphic available
Description	Zinc finger protein 346 (Just another zinc finger protein).

NFM_MOUSE
NC score	0.010756 (rank : 110)	θ value	0.0961366 (rank : 28)
Query Neighborhood Hits	96	Target Neighborhood Hits	1159	Shared Neighborhood Hits	18
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

ES8L2_HUMAN
NC score	0.010640 (rank : 111)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	96	Target Neighborhood Hits	193	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9	Gene names	EPS8L2, EPS8R2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

NFAC3_HUMAN
NC score	0.010453 (rank : 112)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	96	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	Q12968, O75211, Q14516, Q99840, Q99841, Q99842	Gene names	NFATC3, NFAT4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

WRN_MOUSE
NC score	0.009976 (rank : 113)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	96	Target Neighborhood Hits	295	Shared Neighborhood Hits	5
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

NKTR_MOUSE
NC score	0.009912 (rank : 114)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	96	Target Neighborhood Hits	417	Shared Neighborhood Hits	13
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

PYGO1_HUMAN
NC score	0.009866 (rank : 115)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	96	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y3Y4	Gene names	PYGO1
Domain Architecture
Description	Pygopus homolog 1.

ZN451_MOUSE
NC score	0.009080 (rank : 116)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	96	Target Neighborhood Hits	643	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C0P7	Gene names	Znf451, Zfp451
Domain Architecture	No domain graphic available
Description	Zinc finger protein 451.

MNAB_MOUSE
NC score	0.009078 (rank : 117)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	96	Target Neighborhood Hits	231	Shared Neighborhood Hits	9
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

TAI12_HUMAN
NC score	0.008909 (rank : 118)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	96	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H175	Gene names	TAIP12, C12orf22
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 12 (TAIP-12).

AR13B_MOUSE
NC score	0.008777 (rank : 119)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	96	Target Neighborhood Hits	245	Shared Neighborhood Hits	3
SwissProt Accessions	Q640N2	Gene names	Arl13b, Arl2l1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

PRLR_HUMAN
NC score	0.008659 (rank : 120)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	96	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	P16471, Q16354, Q9BX87	Gene names	PRLR
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

FA13A_HUMAN
NC score	0.007736 (rank : 121)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	96	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

TIF1G_HUMAN
NC score	0.006885 (rank : 122)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	96	Target Neighborhood Hits	410	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

RRBP1_MOUSE
NC score	0.006756 (rank : 123)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	96	Target Neighborhood Hits	1650	Shared Neighborhood Hits	21
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

HTF4_HUMAN
NC score	0.005919 (rank : 124)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	96	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

ZN507_HUMAN
NC score	0.003913 (rank : 125)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	96	Target Neighborhood Hits	739	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TCN5	Gene names	ZNF507
Domain Architecture	No domain graphic available
Description	Zinc finger protein 507.

PTPRZ_HUMAN
NC score	0.003873 (rank : 126)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	96	Target Neighborhood Hits	255	Shared Neighborhood Hits	7
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

CO5A2_HUMAN
NC score	0.003631 (rank : 127)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	96	Target Neighborhood Hits	760	Shared Neighborhood Hits	11
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

ANK3_HUMAN
NC score	0.003357 (rank : 128)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	96	Target Neighborhood Hits	853	Shared Neighborhood Hits	23
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

HIPK2_HUMAN
NC score	-0.000306 (rank : 129)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	96	Target Neighborhood Hits	845	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H2X6, Q75MR7, Q8WWI4, Q9H2Y1	Gene names	HIPK2
Domain Architecture
Description	Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (hHIPk2).