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Network neighborhood for query Sequence : ARH_HUMAN

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ARH_HUMAN
SwissProt Accessions	Q5SW96, Q6TQS9, Q8N2Y0, Q9UFI9	Gene names	LDLRAP1, ARH
Domain Architecture	No domain graphic available
Description	Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ARH_HUMAN
θ value	7.23842e-175 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q5SW96, Q6TQS9, Q8N2Y0, Q9UFI9	Gene names	LDLRAP1, ARH
Domain Architecture	No domain graphic available
Description	Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein).

ARH_MOUSE
θ value	3.73483e-155 (rank : 2)	NC score	0.989120 (rank : 2)
Query Neighborhood Hits	38	Target Neighborhood Hits	32	Shared Neighborhood Hits	29
SwissProt Accessions	Q8C142, Q6NWV6, Q8VDQ0	Gene names	Ldlrap1, Arh
Domain Architecture	No domain graphic available
Description	Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein homolog).

NUMB_HUMAN
θ value	3.18553e-13 (rank : 3)	NC score	0.588098 (rank : 4)
Query Neighborhood Hits	38	Target Neighborhood Hits	112	Shared Neighborhood Hits	27
SwissProt Accessions	P49757, Q6NUQ7, Q86SY1, Q8WW73, Q9UBG1, Q9UEQ4, Q9UKE8, Q9UKE9, Q9UKF0, Q9UQJ4	Gene names	NUMB
Domain Architecture
Description	Protein numb homolog (h-Numb) (Protein S171).

CAPON_HUMAN
θ value	4.16044e-13 (rank : 4)	NC score	0.536488 (rank : 7)
Query Neighborhood Hits	38	Target Neighborhood Hits	35	Shared Neighborhood Hits	19
SwissProt Accessions	O75052, O43564	Gene names	NOS1AP, CAPON, KIAA0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).

NUMB_MOUSE
θ value	1.58096e-12 (rank : 5)	NC score	0.588644 (rank : 3)
Query Neighborhood Hits	38	Target Neighborhood Hits	91	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QZS3, P70422, Q8CIB1, Q9DC57, Q9QZR1, Q9QZS4	Gene names	Numb
Domain Architecture
Description	Protein numb homolog (m-Numb) (m-Nb).

CAPON_MOUSE
θ value	2.69671e-12 (rank : 6)	NC score	0.537117 (rank : 6)
Query Neighborhood Hits	38	Target Neighborhood Hits	34	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D3A8, Q80TZ6	Gene names	Nos1ap, Capon, Kiaa0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).

NUMBL_HUMAN
θ value	7.84624e-12 (rank : 7)	NC score	0.524131 (rank : 8)
Query Neighborhood Hits	38	Target Neighborhood Hits	394	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

NUMBL_MOUSE
θ value	7.84624e-12 (rank : 8)	NC score	0.587221 (rank : 5)
Query Neighborhood Hits	38	Target Neighborhood Hits	147	Shared Neighborhood Hits	22
SwissProt Accessions	O08919, Q6NVG8	Gene names	Numbl, Nbl
Domain Architecture
Description	Numb-like protein.

DAB1_HUMAN
θ value	2.13673e-09 (rank : 9)	NC score	0.453913 (rank : 10)
Query Neighborhood Hits	38	Target Neighborhood Hits	219	Shared Neighborhood Hits	14
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

DAB1_MOUSE
θ value	2.13673e-09 (rank : 10)	NC score	0.469636 (rank : 9)
Query Neighborhood Hits	38	Target Neighborhood Hits	145	Shared Neighborhood Hits	14
SwissProt Accessions	P97318, P97316, P97317	Gene names	Dab1
Domain Architecture
Description	Disabled homolog 1.

FA43A_HUMAN
θ value	5.26297e-08 (rank : 11)	NC score	0.408638 (rank : 11)
Query Neighborhood Hits	38	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N2R8, Q8IXP4, Q8WZ07	Gene names	FAM43A
Domain Architecture	No domain graphic available
Description	Protein FAM43A.

FA43A_MOUSE
θ value	5.26297e-08 (rank : 12)	NC score	0.408529 (rank : 12)
Query Neighborhood Hits	38	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BUP8, Q8R231	Gene names	Fam43a
Domain Architecture	No domain graphic available
Description	Protein FAM43A.

DAB2_HUMAN
θ value	3.41135e-07 (rank : 13)	NC score	0.396586 (rank : 13)
Query Neighborhood Hits	38	Target Neighborhood Hits	197	Shared Neighborhood Hits	14
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

ANKS1_MOUSE
θ value	7.59969e-07 (rank : 14)	NC score	0.187416 (rank : 18)
Query Neighborhood Hits	38	Target Neighborhood Hits	453	Shared Neighborhood Hits	24
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ANKS1_HUMAN
θ value	9.92553e-07 (rank : 15)	NC score	0.177961 (rank : 19)
Query Neighborhood Hits	38	Target Neighborhood Hits	438	Shared Neighborhood Hits	24
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

DAB2_MOUSE
θ value	2.21117e-06 (rank : 16)	NC score	0.391061 (rank : 14)
Query Neighborhood Hits	38	Target Neighborhood Hits	163	Shared Neighborhood Hits	13
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

FA43B_HUMAN
θ value	1.43324e-05 (rank : 17)	NC score	0.336055 (rank : 15)
Query Neighborhood Hits	38	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZT52	Gene names	FAM43B
Domain Architecture	No domain graphic available
Description	Protein FAM43B.

JIP1_MOUSE
θ value	0.00298849 (rank : 18)	NC score	0.229275 (rank : 16)
Query Neighborhood Hits	38	Target Neighborhood Hits	259	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JIP1_HUMAN
θ value	0.00390308 (rank : 19)	NC score	0.224156 (rank : 17)
Query Neighborhood Hits	38	Target Neighborhood Hits	271	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

SHC2_MOUSE
θ value	0.0148317 (rank : 20)	NC score	0.130571 (rank : 20)
Query Neighborhood Hits	38	Target Neighborhood Hits	144	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

SHC2_HUMAN
θ value	0.0252991 (rank : 21)	NC score	0.127534 (rank : 21)
Query Neighborhood Hits	38	Target Neighborhood Hits	170	Shared Neighborhood Hits	14
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

APBB2_MOUSE
θ value	0.0736092 (rank : 22)	NC score	0.122806 (rank : 23)
Query Neighborhood Hits	38	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

APBB2_HUMAN
θ value	0.125558 (rank : 23)	NC score	0.125176 (rank : 22)
Query Neighborhood Hits	38	Target Neighborhood Hits	96	Shared Neighborhood Hits	14
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

SHC1_HUMAN
θ value	0.21417 (rank : 24)	NC score	0.099103 (rank : 24)
Query Neighborhood Hits	38	Target Neighborhood Hits	170	Shared Neighborhood Hits	12
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC1_MOUSE
θ value	0.21417 (rank : 25)	NC score	0.098509 (rank : 25)
Query Neighborhood Hits	38	Target Neighborhood Hits	180	Shared Neighborhood Hits	11
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

APBA3_HUMAN
θ value	1.06291 (rank : 26)	NC score	0.035523 (rank : 37)
Query Neighborhood Hits	38	Target Neighborhood Hits	201	Shared Neighborhood Hits	8
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

TBCD1_HUMAN
θ value	1.38821 (rank : 27)	NC score	0.055417 (rank : 36)
Query Neighborhood Hits	38	Target Neighborhood Hits	276	Shared Neighborhood Hits	10
SwissProt Accessions	Q86TI0, Q96K82, Q9UPP4	Gene names	TBC1D1, KIAA1108
Domain Architecture
Description	TBC1 domain family member 1.

TBCD4_HUMAN
θ value	3.0926 (rank : 28)	NC score	0.063492 (rank : 33)
Query Neighborhood Hits	38	Target Neighborhood Hits	357	Shared Neighborhood Hits	13
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

TBCD4_MOUSE
θ value	3.0926 (rank : 29)	NC score	0.064790 (rank : 32)
Query Neighborhood Hits	38	Target Neighborhood Hits	276	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

APBB1_MOUSE
θ value	4.03905 (rank : 30)	NC score	0.083029 (rank : 26)
Query Neighborhood Hits	38	Target Neighborhood Hits	75	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QXJ1, O08642, Q3TPU0, Q8BNF4, Q8BSR9	Gene names	Apbb1, Fe65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

HIC2_HUMAN
θ value	4.03905 (rank : 31)	NC score	-0.000495 (rank : 43)
Query Neighborhood Hits	38	Target Neighborhood Hits	820	Shared Neighborhood Hits	4
SwissProt Accessions	Q96JB3, Q96KR3, Q9NSM9, Q9UPX9	Gene names	HIC2, HRG22, KIAA1020, ZBTB30
Domain Architecture
Description	Hypermethylated in cancer 2 protein (Hic-2) (Hic-3) (HIC1-related gene on chromosome 22) (Zinc finger and BTB domain-containing protein 30).

APBB1_HUMAN
θ value	5.27518 (rank : 32)	NC score	0.081047 (rank : 27)
Query Neighborhood Hits	38	Target Neighborhood Hits	62	Shared Neighborhood Hits	12
SwissProt Accessions	O00213, Q96A93	Gene names	APBB1, FE65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

TBCD1_MOUSE
θ value	5.27518 (rank : 33)	NC score	0.057679 (rank : 34)
Query Neighborhood Hits	38	Target Neighborhood Hits	241	Shared Neighborhood Hits	10
SwissProt Accessions	Q60949, Q80TJ9, Q923F8	Gene names	Tbc1d1, Kiaa1108, Tbc1
Domain Architecture
Description	TBC1 domain family member 1.

EPS8_MOUSE
θ value	6.88961 (rank : 34)	NC score	0.019944 (rank : 38)
Query Neighborhood Hits	38	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

GLU2B_MOUSE
θ value	6.88961 (rank : 35)	NC score	0.012382 (rank : 41)
Query Neighborhood Hits	38	Target Neighborhood Hits	357	Shared Neighborhood Hits	2
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

ITIH3_MOUSE
θ value	6.88961 (rank : 36)	NC score	0.012729 (rank : 40)
Query Neighborhood Hits	38	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q61704	Gene names	Itih3
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H3 precursor (ITI heavy chain H3) (Inter-alpha-inhibitor heavy chain 3).

PO2F1_MOUSE
θ value	6.88961 (rank : 37)	NC score	0.005592 (rank : 42)
Query Neighborhood Hits	38	Target Neighborhood Hits	408	Shared Neighborhood Hits	3
SwissProt Accessions	P25425, Q61994, Q63891, Q6Y681, Q7TSD0, Q8BT04, Q8K570, Q99JH0, Q9WTZ4, Q9WTZ5, Q9WTZ6	Gene names	Pou2f1, Oct-1, Otf-1, Otf1
Domain Architecture
Description	POU domain, class 2, transcription factor 1 (Octamer-binding transcription factor 1) (Oct-1) (OTF-1) (NF-A1).

EPS8_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.018267 (rank : 39)
Query Neighborhood Hits	38	Target Neighborhood Hits	151	Shared Neighborhood Hits	4
SwissProt Accessions	Q12929, Q8N6J0	Gene names	EPS8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

JIP2_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.080589 (rank : 28)
Query Neighborhood Hits	38	Target Neighborhood Hits	288	Shared Neighborhood Hits	8
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

JIP2_MOUSE
θ value	θ > 10 (rank : 40)	NC score	0.078971 (rank : 29)
Query Neighborhood Hits	38	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

SHC3_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.077929 (rank : 31)
Query Neighborhood Hits	38	Target Neighborhood Hits	155	Shared Neighborhood Hits	11
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

SHC3_MOUSE
θ value	θ > 10 (rank : 42)	NC score	0.078284 (rank : 30)
Query Neighborhood Hits	38	Target Neighborhood Hits	151	Shared Neighborhood Hits	12
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

ZN207_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.056816 (rank : 35)
Query Neighborhood Hits	38	Target Neighborhood Hits	326	Shared Neighborhood Hits	4
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

Hits sorted by NC score

ARH_HUMAN
NC score	0.999962 (rank : 1)	θ value	7.23842e-175 (rank : 1)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q5SW96, Q6TQS9, Q8N2Y0, Q9UFI9	Gene names	LDLRAP1, ARH
Domain Architecture	No domain graphic available
Description	Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein).

ARH_MOUSE
NC score	0.989120 (rank : 2)	θ value	3.73483e-155 (rank : 2)
Query Neighborhood Hits	38	Target Neighborhood Hits	32	Shared Neighborhood Hits	29
SwissProt Accessions	Q8C142, Q6NWV6, Q8VDQ0	Gene names	Ldlrap1, Arh
Domain Architecture	No domain graphic available
Description	Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein homolog).

NUMB_MOUSE
NC score	0.588644 (rank : 3)	θ value	1.58096e-12 (rank : 5)
Query Neighborhood Hits	38	Target Neighborhood Hits	91	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QZS3, P70422, Q8CIB1, Q9DC57, Q9QZR1, Q9QZS4	Gene names	Numb
Domain Architecture
Description	Protein numb homolog (m-Numb) (m-Nb).

NUMB_HUMAN
NC score	0.588098 (rank : 4)	θ value	3.18553e-13 (rank : 3)
Query Neighborhood Hits	38	Target Neighborhood Hits	112	Shared Neighborhood Hits	27
SwissProt Accessions	P49757, Q6NUQ7, Q86SY1, Q8WW73, Q9UBG1, Q9UEQ4, Q9UKE8, Q9UKE9, Q9UKF0, Q9UQJ4	Gene names	NUMB
Domain Architecture
Description	Protein numb homolog (h-Numb) (Protein S171).

NUMBL_MOUSE
NC score	0.587221 (rank : 5)	θ value	7.84624e-12 (rank : 8)
Query Neighborhood Hits	38	Target Neighborhood Hits	147	Shared Neighborhood Hits	22
SwissProt Accessions	O08919, Q6NVG8	Gene names	Numbl, Nbl
Domain Architecture
Description	Numb-like protein.

CAPON_MOUSE
NC score	0.537117 (rank : 6)	θ value	2.69671e-12 (rank : 6)
Query Neighborhood Hits	38	Target Neighborhood Hits	34	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D3A8, Q80TZ6	Gene names	Nos1ap, Capon, Kiaa0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).

CAPON_HUMAN
NC score	0.536488 (rank : 7)	θ value	4.16044e-13 (rank : 4)
Query Neighborhood Hits	38	Target Neighborhood Hits	35	Shared Neighborhood Hits	19
SwissProt Accessions	O75052, O43564	Gene names	NOS1AP, CAPON, KIAA0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).

NUMBL_HUMAN
NC score	0.524131 (rank : 8)	θ value	7.84624e-12 (rank : 7)
Query Neighborhood Hits	38	Target Neighborhood Hits	394	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

DAB1_MOUSE
NC score	0.469636 (rank : 9)	θ value	2.13673e-09 (rank : 10)
Query Neighborhood Hits	38	Target Neighborhood Hits	145	Shared Neighborhood Hits	14
SwissProt Accessions	P97318, P97316, P97317	Gene names	Dab1
Domain Architecture
Description	Disabled homolog 1.

DAB1_HUMAN
NC score	0.453913 (rank : 10)	θ value	2.13673e-09 (rank : 9)
Query Neighborhood Hits	38	Target Neighborhood Hits	219	Shared Neighborhood Hits	14
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

FA43A_HUMAN
NC score	0.408638 (rank : 11)	θ value	5.26297e-08 (rank : 11)
Query Neighborhood Hits	38	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N2R8, Q8IXP4, Q8WZ07	Gene names	FAM43A
Domain Architecture	No domain graphic available
Description	Protein FAM43A.

FA43A_MOUSE
NC score	0.408529 (rank : 12)	θ value	5.26297e-08 (rank : 12)
Query Neighborhood Hits	38	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BUP8, Q8R231	Gene names	Fam43a
Domain Architecture	No domain graphic available
Description	Protein FAM43A.

DAB2_HUMAN
NC score	0.396586 (rank : 13)	θ value	3.41135e-07 (rank : 13)
Query Neighborhood Hits	38	Target Neighborhood Hits	197	Shared Neighborhood Hits	14
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

DAB2_MOUSE
NC score	0.391061 (rank : 14)	θ value	2.21117e-06 (rank : 16)
Query Neighborhood Hits	38	Target Neighborhood Hits	163	Shared Neighborhood Hits	13
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

FA43B_HUMAN
NC score	0.336055 (rank : 15)	θ value	1.43324e-05 (rank : 17)
Query Neighborhood Hits	38	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZT52	Gene names	FAM43B
Domain Architecture	No domain graphic available
Description	Protein FAM43B.

JIP1_MOUSE
NC score	0.229275 (rank : 16)	θ value	0.00298849 (rank : 18)
Query Neighborhood Hits	38	Target Neighborhood Hits	259	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JIP1_HUMAN
NC score	0.224156 (rank : 17)	θ value	0.00390308 (rank : 19)
Query Neighborhood Hits	38	Target Neighborhood Hits	271	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

ANKS1_MOUSE
NC score	0.187416 (rank : 18)	θ value	7.59969e-07 (rank : 14)
Query Neighborhood Hits	38	Target Neighborhood Hits	453	Shared Neighborhood Hits	24
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ANKS1_HUMAN
NC score	0.177961 (rank : 19)	θ value	9.92553e-07 (rank : 15)
Query Neighborhood Hits	38	Target Neighborhood Hits	438	Shared Neighborhood Hits	24
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

SHC2_MOUSE
NC score	0.130571 (rank : 20)	θ value	0.0148317 (rank : 20)
Query Neighborhood Hits	38	Target Neighborhood Hits	144	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

SHC2_HUMAN
NC score	0.127534 (rank : 21)	θ value	0.0252991 (rank : 21)
Query Neighborhood Hits	38	Target Neighborhood Hits	170	Shared Neighborhood Hits	14
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

APBB2_HUMAN
NC score	0.125176 (rank : 22)	θ value	0.125558 (rank : 23)
Query Neighborhood Hits	38	Target Neighborhood Hits	96	Shared Neighborhood Hits	14
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

APBB2_MOUSE
NC score	0.122806 (rank : 23)	θ value	0.0736092 (rank : 22)
Query Neighborhood Hits	38	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

SHC1_HUMAN
NC score	0.099103 (rank : 24)	θ value	0.21417 (rank : 24)
Query Neighborhood Hits	38	Target Neighborhood Hits	170	Shared Neighborhood Hits	12
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC1_MOUSE
NC score	0.098509 (rank : 25)	θ value	0.21417 (rank : 25)
Query Neighborhood Hits	38	Target Neighborhood Hits	180	Shared Neighborhood Hits	11
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

APBB1_MOUSE
NC score	0.083029 (rank : 26)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	38	Target Neighborhood Hits	75	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QXJ1, O08642, Q3TPU0, Q8BNF4, Q8BSR9	Gene names	Apbb1, Fe65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

APBB1_HUMAN
NC score	0.081047 (rank : 27)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	38	Target Neighborhood Hits	62	Shared Neighborhood Hits	12
SwissProt Accessions	O00213, Q96A93	Gene names	APBB1, FE65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

JIP2_HUMAN
NC score	0.080589 (rank : 28)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	38	Target Neighborhood Hits	288	Shared Neighborhood Hits	8
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

JIP2_MOUSE
NC score	0.078971 (rank : 29)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	38	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

SHC3_MOUSE
NC score	0.078284 (rank : 30)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	38	Target Neighborhood Hits	151	Shared Neighborhood Hits	12
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

SHC3_HUMAN
NC score	0.077929 (rank : 31)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	38	Target Neighborhood Hits	155	Shared Neighborhood Hits	11
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

TBCD4_MOUSE
NC score	0.064790 (rank : 32)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	38	Target Neighborhood Hits	276	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

TBCD4_HUMAN
NC score	0.063492 (rank : 33)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	38	Target Neighborhood Hits	357	Shared Neighborhood Hits	13
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

TBCD1_MOUSE
NC score	0.057679 (rank : 34)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	38	Target Neighborhood Hits	241	Shared Neighborhood Hits	10
SwissProt Accessions	Q60949, Q80TJ9, Q923F8	Gene names	Tbc1d1, Kiaa1108, Tbc1
Domain Architecture
Description	TBC1 domain family member 1.

ZN207_HUMAN
NC score	0.056816 (rank : 35)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	38	Target Neighborhood Hits	326	Shared Neighborhood Hits	4
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

TBCD1_HUMAN
NC score	0.055417 (rank : 36)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	38	Target Neighborhood Hits	276	Shared Neighborhood Hits	10
SwissProt Accessions	Q86TI0, Q96K82, Q9UPP4	Gene names	TBC1D1, KIAA1108
Domain Architecture
Description	TBC1 domain family member 1.

APBA3_HUMAN
NC score	0.035523 (rank : 37)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	38	Target Neighborhood Hits	201	Shared Neighborhood Hits	8
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

EPS8_MOUSE
NC score	0.019944 (rank : 38)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	38	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

EPS8_HUMAN
NC score	0.018267 (rank : 39)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	38	Target Neighborhood Hits	151	Shared Neighborhood Hits	4
SwissProt Accessions	Q12929, Q8N6J0	Gene names	EPS8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

ITIH3_MOUSE
NC score	0.012729 (rank : 40)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	38	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q61704	Gene names	Itih3
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H3 precursor (ITI heavy chain H3) (Inter-alpha-inhibitor heavy chain 3).

GLU2B_MOUSE
NC score	0.012382 (rank : 41)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	38	Target Neighborhood Hits	357	Shared Neighborhood Hits	2
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

PO2F1_MOUSE
NC score	0.005592 (rank : 42)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	38	Target Neighborhood Hits	408	Shared Neighborhood Hits	3
SwissProt Accessions	P25425, Q61994, Q63891, Q6Y681, Q7TSD0, Q8BT04, Q8K570, Q99JH0, Q9WTZ4, Q9WTZ5, Q9WTZ6	Gene names	Pou2f1, Oct-1, Otf-1, Otf1
Domain Architecture
Description	POU domain, class 2, transcription factor 1 (Octamer-binding transcription factor 1) (Oct-1) (OTF-1) (NF-A1).

HIC2_HUMAN
NC score	-0.000495 (rank : 43)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	38	Target Neighborhood Hits	820	Shared Neighborhood Hits	4
SwissProt Accessions	Q96JB3, Q96KR3, Q9NSM9, Q9UPX9	Gene names	HIC2, HRG22, KIAA1020, ZBTB30
Domain Architecture
Description	Hypermethylated in cancer 2 protein (Hic-2) (Hic-3) (HIC1-related gene on chromosome 22) (Zinc finger and BTB domain-containing protein 30).