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Network neighborhood for query Sequence : NUMB_HUMAN

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NUMB_HUMAN
SwissProt Accessions	P49757, Q6NUQ7, Q86SY1, Q8WW73, Q9UBG1, Q9UEQ4, Q9UKE8, Q9UKE9, Q9UKF0, Q9UQJ4	Gene names	NUMB
Domain Architecture
Description	Protein numb homolog (h-Numb) (Protein S171).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NUMB_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	112	Target Neighborhood Hits	112	Shared Neighborhood Hits	112
SwissProt Accessions	P49757, Q6NUQ7, Q86SY1, Q8WW73, Q9UBG1, Q9UEQ4, Q9UKE8, Q9UKE9, Q9UKF0, Q9UQJ4	Gene names	NUMB
Domain Architecture
Description	Protein numb homolog (h-Numb) (Protein S171).

NUMB_MOUSE
θ value	0 (rank : 2)	NC score	0.983232 (rank : 2)
Query Neighborhood Hits	112	Target Neighborhood Hits	91	Shared Neighborhood Hits	48
SwissProt Accessions	Q9QZS3, P70422, Q8CIB1, Q9DC57, Q9QZR1, Q9QZS4	Gene names	Numb
Domain Architecture
Description	Protein numb homolog (m-Numb) (m-Nb).

NUMBL_HUMAN
θ value	6.17048e-150 (rank : 3)	NC score	0.850814 (rank : 4)
Query Neighborhood Hits	112	Target Neighborhood Hits	394	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

NUMBL_MOUSE
θ value	8.0589e-150 (rank : 4)	NC score	0.937837 (rank : 3)
Query Neighborhood Hits	112	Target Neighborhood Hits	147	Shared Neighborhood Hits	30
SwissProt Accessions	O08919, Q6NVG8	Gene names	Numbl, Nbl
Domain Architecture
Description	Numb-like protein.

ARH_HUMAN
θ value	3.18553e-13 (rank : 5)	NC score	0.588098 (rank : 5)
Query Neighborhood Hits	112	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	Q5SW96, Q6TQS9, Q8N2Y0, Q9UFI9	Gene names	LDLRAP1, ARH
Domain Architecture	No domain graphic available
Description	Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein).

ARH_MOUSE
θ value	1.33837e-11 (rank : 6)	NC score	0.576376 (rank : 6)
Query Neighborhood Hits	112	Target Neighborhood Hits	32	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C142, Q6NWV6, Q8VDQ0	Gene names	Ldlrap1, Arh
Domain Architecture	No domain graphic available
Description	Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein homolog).

DAB1_HUMAN
θ value	1.53129e-07 (rank : 7)	NC score	0.390019 (rank : 8)
Query Neighborhood Hits	112	Target Neighborhood Hits	219	Shared Neighborhood Hits	36
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

DAB1_MOUSE
θ value	1.53129e-07 (rank : 8)	NC score	0.397747 (rank : 7)
Query Neighborhood Hits	112	Target Neighborhood Hits	145	Shared Neighborhood Hits	25
SwissProt Accessions	P97318, P97316, P97317	Gene names	Dab1
Domain Architecture
Description	Disabled homolog 1.

ANKS1_HUMAN
θ value	3.41135e-07 (rank : 9)	NC score	0.157028 (rank : 18)
Query Neighborhood Hits	112	Target Neighborhood Hits	438	Shared Neighborhood Hits	24
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ANKS1_MOUSE
θ value	3.41135e-07 (rank : 10)	NC score	0.165522 (rank : 17)
Query Neighborhood Hits	112	Target Neighborhood Hits	453	Shared Neighborhood Hits	27
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

DAB2_MOUSE
θ value	4.1701e-05 (rank : 11)	NC score	0.334251 (rank : 12)
Query Neighborhood Hits	112	Target Neighborhood Hits	163	Shared Neighborhood Hits	25
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

DAB2_HUMAN
θ value	5.44631e-05 (rank : 12)	NC score	0.337659 (rank : 11)
Query Neighborhood Hits	112	Target Neighborhood Hits	197	Shared Neighborhood Hits	33
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

CAPON_HUMAN
θ value	0.000121331 (rank : 13)	NC score	0.351611 (rank : 9)
Query Neighborhood Hits	112	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	O75052, O43564	Gene names	NOS1AP, CAPON, KIAA0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).

CAPON_MOUSE
θ value	0.00020696 (rank : 14)	NC score	0.340742 (rank : 10)
Query Neighborhood Hits	112	Target Neighborhood Hits	34	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D3A8, Q80TZ6	Gene names	Nos1ap, Capon, Kiaa0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).

JIP1_MOUSE
θ value	0.00298849 (rank : 15)	NC score	0.213535 (rank : 13)
Query Neighborhood Hits	112	Target Neighborhood Hits	259	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JIP1_HUMAN
θ value	0.00665767 (rank : 16)	NC score	0.203664 (rank : 14)
Query Neighborhood Hits	112	Target Neighborhood Hits	271	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

SHC2_MOUSE
θ value	0.00869519 (rank : 17)	NC score	0.110911 (rank : 20)
Query Neighborhood Hits	112	Target Neighborhood Hits	144	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

SHC2_HUMAN
θ value	0.0113563 (rank : 18)	NC score	0.107710 (rank : 21)
Query Neighborhood Hits	112	Target Neighborhood Hits	170	Shared Neighborhood Hits	13
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

AAK1_MOUSE
θ value	0.0193708 (rank : 19)	NC score	0.017509 (rank : 99)
Query Neighborhood Hits	112	Target Neighborhood Hits	1051	Shared Neighborhood Hits	27
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

MILK1_MOUSE
θ value	0.0330416 (rank : 20)	NC score	0.038505 (rank : 67)
Query Neighborhood Hits	112	Target Neighborhood Hits	788	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

APBB2_HUMAN
θ value	0.0431538 (rank : 21)	NC score	0.122400 (rank : 19)
Query Neighborhood Hits	112	Target Neighborhood Hits	96	Shared Neighborhood Hits	19
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

PHF2_MOUSE
θ value	0.0431538 (rank : 22)	NC score	0.035188 (rank : 73)
Query Neighborhood Hits	112	Target Neighborhood Hits	241	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

ANX11_MOUSE
θ value	0.0563607 (rank : 23)	NC score	0.038691 (rank : 66)
Query Neighborhood Hits	112	Target Neighborhood Hits	200	Shared Neighborhood Hits	18
SwissProt Accessions	P97384	Gene names	Anxa11, Anx11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50).

FA43A_HUMAN
θ value	0.0961366 (rank : 24)	NC score	0.200841 (rank : 15)
Query Neighborhood Hits	112	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N2R8, Q8IXP4, Q8WZ07	Gene names	FAM43A
Domain Architecture	No domain graphic available
Description	Protein FAM43A.

FA43A_MOUSE
θ value	0.0961366 (rank : 25)	NC score	0.200742 (rank : 16)
Query Neighborhood Hits	112	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BUP8, Q8R231	Gene names	Fam43a
Domain Architecture	No domain graphic available
Description	Protein FAM43A.

TM108_MOUSE
θ value	0.125558 (rank : 26)	NC score	0.062510 (rank : 32)
Query Neighborhood Hits	112	Target Neighborhood Hits	336	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

BSN_HUMAN
θ value	0.279714 (rank : 27)	NC score	0.056732 (rank : 39)
Query Neighborhood Hits	112	Target Neighborhood Hits	1537	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

NOTC2_HUMAN
θ value	0.279714 (rank : 28)	NC score	0.024513 (rank : 87)
Query Neighborhood Hits	112	Target Neighborhood Hits	1113	Shared Neighborhood Hits	36
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PCLO_HUMAN
θ value	0.365318 (rank : 29)	NC score	0.056206 (rank : 41)
Query Neighborhood Hits	112	Target Neighborhood Hits	2046	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

CBP_MOUSE
θ value	0.47712 (rank : 30)	NC score	0.064535 (rank : 31)
Query Neighborhood Hits	112	Target Neighborhood Hits	1051	Shared Neighborhood Hits	61
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

HNF1A_HUMAN
θ value	0.47712 (rank : 31)	NC score	0.040799 (rank : 63)
Query Neighborhood Hits	112	Target Neighborhood Hits	193	Shared Neighborhood Hits	12
SwissProt Accessions	P20823, Q99861	Gene names	TCF1, HNF1A
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1).

MUC2_HUMAN
θ value	0.47712 (rank : 32)	NC score	0.033116 (rank : 79)
Query Neighborhood Hits	112	Target Neighborhood Hits	906	Shared Neighborhood Hits	35
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

SN1L1_HUMAN
θ value	0.47712 (rank : 33)	NC score	0.005383 (rank : 123)
Query Neighborhood Hits	112	Target Neighborhood Hits	911	Shared Neighborhood Hits	9
SwissProt Accessions	P57059, Q5R2V5, Q86YJ2	Gene names	SNF1LK
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK).

MLL3_MOUSE
θ value	0.62314 (rank : 34)	NC score	0.045956 (rank : 57)
Query Neighborhood Hits	112	Target Neighborhood Hits	1399	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

TCRG1_MOUSE
θ value	0.62314 (rank : 35)	NC score	0.042296 (rank : 60)
Query Neighborhood Hits	112	Target Neighborhood Hits	947	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

APBB1_MOUSE
θ value	0.813845 (rank : 36)	NC score	0.071348 (rank : 27)
Query Neighborhood Hits	112	Target Neighborhood Hits	75	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QXJ1, O08642, Q3TPU0, Q8BNF4, Q8BSR9	Gene names	Apbb1, Fe65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

FBX43_HUMAN
θ value	0.813845 (rank : 37)	NC score	0.032452 (rank : 81)
Query Neighborhood Hits	112	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q4G163	Gene names	FBXO43, EMI2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

PDC6I_MOUSE
θ value	0.813845 (rank : 38)	NC score	0.060421 (rank : 33)
Query Neighborhood Hits	112	Target Neighborhood Hits	275	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

RERE_HUMAN
θ value	0.813845 (rank : 39)	NC score	0.052453 (rank : 49)
Query Neighborhood Hits	112	Target Neighborhood Hits	779	Shared Neighborhood Hits	42
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

T22D2_HUMAN
θ value	0.813845 (rank : 40)	NC score	0.037201 (rank : 69)
Query Neighborhood Hits	112	Target Neighborhood Hits	250	Shared Neighborhood Hits	19
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

TARA_HUMAN
θ value	0.813845 (rank : 41)	NC score	0.036569 (rank : 72)
Query Neighborhood Hits	112	Target Neighborhood Hits	1626	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CJ012_HUMAN
θ value	1.06291 (rank : 42)	NC score	0.056768 (rank : 38)
Query Neighborhood Hits	112	Target Neighborhood Hits	467	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

CN032_MOUSE
θ value	1.06291 (rank : 43)	NC score	0.072236 (rank : 26)
Query Neighborhood Hits	112	Target Neighborhood Hits	233	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

DIDO1_HUMAN
θ value	1.06291 (rank : 44)	NC score	0.041291 (rank : 61)
Query Neighborhood Hits	112	Target Neighborhood Hits	960	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

SRRM2_MOUSE
θ value	1.06291 (rank : 45)	NC score	0.047536 (rank : 56)
Query Neighborhood Hits	112	Target Neighborhood Hits	1470	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TCRG1_HUMAN
θ value	1.06291 (rank : 46)	NC score	0.040992 (rank : 62)
Query Neighborhood Hits	112	Target Neighborhood Hits	929	Shared Neighborhood Hits	30
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

B3A2_HUMAN
θ value	1.38821 (rank : 47)	NC score	0.012133 (rank : 110)
Query Neighborhood Hits	112	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	P04920, Q45EY5, Q969L3	Gene names	SLC4A2, AE2, EPB3L1, HKB3, MPB3L
Domain Architecture
Description	Anion exchange protein 2 (Non-erythroid band 3-like protein) (AE2 anion exchanger) (Solute carrier family 4 member 2) (BND3L).

CBP_HUMAN
θ value	1.38821 (rank : 48)	NC score	0.050309 (rank : 53)
Query Neighborhood Hits	112	Target Neighborhood Hits	941	Shared Neighborhood Hits	54
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

SEPT9_HUMAN
θ value	1.38821 (rank : 49)	NC score	0.019844 (rank : 95)
Query Neighborhood Hits	112	Target Neighborhood Hits	706	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SREC_HUMAN
θ value	1.38821 (rank : 50)	NC score	0.011435 (rank : 112)
Query Neighborhood Hits	112	Target Neighborhood Hits	645	Shared Neighborhood Hits	9
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

APBB2_MOUSE
θ value	1.81305 (rank : 51)	NC score	0.097242 (rank : 22)
Query Neighborhood Hits	112	Target Neighborhood Hits	88	Shared Neighborhood Hits	18
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

ARI1B_HUMAN
θ value	1.81305 (rank : 52)	NC score	0.042647 (rank : 59)
Query Neighborhood Hits	112	Target Neighborhood Hits	567	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

CXXC6_HUMAN
θ value	1.81305 (rank : 53)	NC score	0.032783 (rank : 80)
Query Neighborhood Hits	112	Target Neighborhood Hits	180	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

ENAH_MOUSE
θ value	1.81305 (rank : 54)	NC score	0.047602 (rank : 55)
Query Neighborhood Hits	112	Target Neighborhood Hits	919	Shared Neighborhood Hits	38
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

NOTC2_MOUSE
θ value	1.81305 (rank : 55)	NC score	0.026092 (rank : 86)
Query Neighborhood Hits	112	Target Neighborhood Hits	1069	Shared Neighborhood Hits	29
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PER2_MOUSE
θ value	1.81305 (rank : 56)	NC score	0.054284 (rank : 46)
Query Neighborhood Hits	112	Target Neighborhood Hits	325	Shared Neighborhood Hits	31
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

PI4KB_HUMAN
θ value	1.81305 (rank : 57)	NC score	0.021271 (rank : 92)
Query Neighborhood Hits	112	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBF8, O15096, P78405, Q9BWR6	Gene names	PIK4CB, PI4KB
Domain Architecture
Description	Phosphatidylinositol 4-kinase beta (EC 2.7.1.67) (PtdIns 4-kinase beta) (PI4Kbeta) (PI4K-beta) (NPIK) (PI4K92).

APBB1_HUMAN
θ value	2.36792 (rank : 58)	NC score	0.065290 (rank : 30)
Query Neighborhood Hits	112	Target Neighborhood Hits	62	Shared Neighborhood Hits	15
SwissProt Accessions	O00213, Q96A93	Gene names	APBB1, FE65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

ATN1_HUMAN
θ value	2.36792 (rank : 59)	NC score	0.055693 (rank : 43)
Query Neighborhood Hits	112	Target Neighborhood Hits	676	Shared Neighborhood Hits	40
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

CN032_HUMAN
θ value	2.36792 (rank : 60)	NC score	0.076326 (rank : 24)
Query Neighborhood Hits	112	Target Neighborhood Hits	267	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CT174_HUMAN
θ value	2.36792 (rank : 61)	NC score	0.033956 (rank : 76)
Query Neighborhood Hits	112	Target Neighborhood Hits	181	Shared Neighborhood Hits	12
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

DTX2_MOUSE
θ value	2.36792 (rank : 62)	NC score	0.016849 (rank : 100)
Query Neighborhood Hits	112	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3P2, Q9CZV3, Q9ER07, Q9ER08	Gene names	Dtx2
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (mDTX2).

FMN2_MOUSE
θ value	2.36792 (rank : 63)	NC score	0.056324 (rank : 40)
Query Neighborhood Hits	112	Target Neighborhood Hits	349	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

LDB3_MOUSE
θ value	2.36792 (rank : 64)	NC score	0.020473 (rank : 93)
Query Neighborhood Hits	112	Target Neighborhood Hits	510	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

NU214_HUMAN
θ value	2.36792 (rank : 65)	NC score	0.044443 (rank : 58)
Query Neighborhood Hits	112	Target Neighborhood Hits	657	Shared Neighborhood Hits	34
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

PO121_MOUSE
θ value	2.36792 (rank : 66)	NC score	0.028694 (rank : 82)
Query Neighborhood Hits	112	Target Neighborhood Hits	345	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

TAF4_HUMAN
θ value	2.36792 (rank : 67)	NC score	0.066998 (rank : 28)
Query Neighborhood Hits	112	Target Neighborhood Hits	687	Shared Neighborhood Hits	39
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

ADA29_HUMAN
θ value	3.0926 (rank : 68)	NC score	0.014566 (rank : 104)
Query Neighborhood Hits	112	Target Neighborhood Hits	247	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

HNF1A_MOUSE
θ value	3.0926 (rank : 69)	NC score	0.038732 (rank : 65)
Query Neighborhood Hits	112	Target Neighborhood Hits	212	Shared Neighborhood Hits	17
SwissProt Accessions	P22361	Gene names	Tcf1, Hnf-1, Hnf-1a, Hnf1a
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1).

HXD12_HUMAN
θ value	3.0926 (rank : 70)	NC score	0.006648 (rank : 122)
Query Neighborhood Hits	112	Target Neighborhood Hits	334	Shared Neighborhood Hits	5
SwissProt Accessions	P35452, Q9NS03	Gene names	HOXD12, HOX4H
Domain Architecture
Description	Homeobox protein Hox-D12 (Hox-4H).

ITSN1_HUMAN
θ value	3.0926 (rank : 71)	NC score	0.009226 (rank : 118)
Query Neighborhood Hits	112	Target Neighborhood Hits	1757	Shared Neighborhood Hits	29
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

MAGC1_HUMAN
θ value	3.0926 (rank : 72)	NC score	0.012850 (rank : 109)
Query Neighborhood Hits	112	Target Neighborhood Hits	431	Shared Neighborhood Hits	21
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

RIMB1_HUMAN
θ value	3.0926 (rank : 73)	NC score	0.014345 (rank : 105)
Query Neighborhood Hits	112	Target Neighborhood Hits	1479	Shared Neighborhood Hits	32
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SH22A_MOUSE
θ value	3.0926 (rank : 74)	NC score	0.021794 (rank : 91)
Query Neighborhood Hits	112	Target Neighborhood Hits	179	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

TEAD1_HUMAN
θ value	3.0926 (rank : 75)	NC score	0.015289 (rank : 103)
Query Neighborhood Hits	112	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P28347	Gene names	TEAD1, TCF13, TEF1
Domain Architecture
Description	Transcriptional enhancer factor TEF-1 (TEA domain family member 1) (TEAD-1) (Protein GT-IIC) (Transcription factor 13) (NTEF-1).

CK024_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.040625 (rank : 64)
Query Neighborhood Hits	112	Target Neighborhood Hits	307	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

DOK2_MOUSE
θ value	4.03905 (rank : 77)	NC score	0.018975 (rank : 97)
Query Neighborhood Hits	112	Target Neighborhood Hits	244	Shared Neighborhood Hits	17
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

GSLG1_MOUSE
θ value	4.03905 (rank : 78)	NC score	0.016667 (rank : 101)
Query Neighborhood Hits	112	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q61543, Q9QZ40	Gene names	Glg1, Esl1, Mg160, Selel
Domain Architecture
Description	Golgi apparatus protein 1 precursor (Golgi sialoglycoprotein MG-160) (E-selectin ligand 1) (ESL-1) (Selel).

PER3_HUMAN
θ value	4.03905 (rank : 79)	NC score	0.036783 (rank : 71)
Query Neighborhood Hits	112	Target Neighborhood Hits	479	Shared Neighborhood Hits	38
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PLXB1_HUMAN
θ value	4.03905 (rank : 80)	NC score	0.011187 (rank : 114)
Query Neighborhood Hits	112	Target Neighborhood Hits	360	Shared Neighborhood Hits	25
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

PO6F2_HUMAN
θ value	4.03905 (rank : 81)	NC score	0.015642 (rank : 102)
Query Neighborhood Hits	112	Target Neighborhood Hits	618	Shared Neighborhood Hits	24
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

BPIL3_MOUSE
θ value	5.27518 (rank : 82)	NC score	0.012956 (rank : 108)
Query Neighborhood Hits	112	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BU51, Q80ZU8	Gene names	Bpil3
Domain Architecture
Description	Bactericidal/permeability-increasing protein-like 3 precursor.

FUBP2_HUMAN
θ value	5.27518 (rank : 83)	NC score	0.033425 (rank : 77)
Query Neighborhood Hits	112	Target Neighborhood Hits	145	Shared Neighborhood Hits	11
SwissProt Accessions	Q92945, O00301, Q9UNT5, Q9UQH5	Gene names	KHSRP, FUBP2
Domain Architecture
Description	Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75).

GGA2_HUMAN
θ value	5.27518 (rank : 84)	NC score	0.011349 (rank : 113)
Query Neighborhood Hits	112	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

HXA3_HUMAN
θ value	5.27518 (rank : 85)	NC score	0.007224 (rank : 121)
Query Neighborhood Hits	112	Target Neighborhood Hits	535	Shared Neighborhood Hits	21
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

MUC7_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.055298 (rank : 44)
Query Neighborhood Hits	112	Target Neighborhood Hits	538	Shared Neighborhood Hits	36
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PRKN2_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.019981 (rank : 94)
Query Neighborhood Hits	112	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	O60260, Q5TFV8, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07	Gene names	PARK2, PRKN
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2).

RD23B_MOUSE
θ value	5.27518 (rank : 88)	NC score	0.026831 (rank : 85)
Query Neighborhood Hits	112	Target Neighborhood Hits	189	Shared Neighborhood Hits	17
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

TLN2_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.007741 (rank : 120)
Query Neighborhood Hits	112	Target Neighborhood Hits	157	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

WWP1_MOUSE
θ value	5.27518 (rank : 90)	NC score	0.008409 (rank : 119)
Query Neighborhood Hits	112	Target Neighborhood Hits	138	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

ZIM10_HUMAN
θ value	5.27518 (rank : 91)	NC score	0.033238 (rank : 78)
Query Neighborhood Hits	112	Target Neighborhood Hits	577	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

BORG5_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.017783 (rank : 98)
Query Neighborhood Hits	112	Target Neighborhood Hits	135	Shared Neighborhood Hits	11
SwissProt Accessions	Q00587, Q96GN1	Gene names	CDC42EP1, BORG5, CEP1, MSE55
Domain Architecture
Description	Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55).

MISS_MOUSE
θ value	6.88961 (rank : 93)	NC score	0.050498 (rank : 52)
Query Neighborhood Hits	112	Target Neighborhood Hits	444	Shared Neighborhood Hits	36
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

PCLO_MOUSE
θ value	6.88961 (rank : 94)	NC score	0.037140 (rank : 70)
Query Neighborhood Hits	112	Target Neighborhood Hits	2275	Shared Neighborhood Hits	63
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PDLI5_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.009585 (rank : 116)
Query Neighborhood Hits	112	Target Neighborhood Hits	322	Shared Neighborhood Hits	11
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PXDC2_MOUSE
θ value	6.88961 (rank : 96)	NC score	0.010826 (rank : 115)
Query Neighborhood Hits	112	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DC11, Q6PET5, Q91ZV6	Gene names	Plxdc2, Tem7r
Domain Architecture	No domain graphic available
Description	Plexin domain-containing protein 2 precursor (Tumor endothelial marker 7-related protein).

R3HD1_HUMAN
θ value	6.88961 (rank : 97)	NC score	0.022350 (rank : 90)
Query Neighborhood Hits	112	Target Neighborhood Hits	203	Shared Neighborhood Hits	16
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

SMRC2_MOUSE
θ value	6.88961 (rank : 98)	NC score	0.037596 (rank : 68)
Query Neighborhood Hits	112	Target Neighborhood Hits	487	Shared Neighborhood Hits	22
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

TBCD4_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.027875 (rank : 84)
Query Neighborhood Hits	112	Target Neighborhood Hits	357	Shared Neighborhood Hits	13
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

TEAD1_MOUSE
θ value	6.88961 (rank : 100)	NC score	0.013017 (rank : 107)
Query Neighborhood Hits	112	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	P30051	Gene names	Tead1, Tcf13, Tef-1, Tef1
Domain Architecture
Description	Transcriptional enhancer factor TEF-1 (TEA domain family member 1) (TEAD-1) (Protein GT-IIC) (Transcription factor 13) (NTEF-1).

ZN750_MOUSE
θ value	6.88961 (rank : 101)	NC score	0.034974 (rank : 74)
Query Neighborhood Hits	112	Target Neighborhood Hits	346	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

CNOT3_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.023392 (rank : 88)
Query Neighborhood Hits	112	Target Neighborhood Hits	425	Shared Neighborhood Hits	19
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CS016_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.034950 (rank : 75)
Query Neighborhood Hits	112	Target Neighborhood Hits	310	Shared Neighborhood Hits	20
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

GBX1_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.003320 (rank : 126)
Query Neighborhood Hits	112	Target Neighborhood Hits	334	Shared Neighborhood Hits	8
SwissProt Accessions	Q14549	Gene names	GBX1
Domain Architecture	No domain graphic available
Description	Homeobox protein GBX-1 (Gastrulation and brain-specific homeobox protein 1).

MCM3A_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.019500 (rank : 96)
Query Neighborhood Hits	112	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	O60318, Q9UMT4	Gene names	MCM3AP, GANP, KIAA0572, MAP80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

MK07_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.004458 (rank : 125)
Query Neighborhood Hits	112	Target Neighborhood Hits	1087	Shared Neighborhood Hits	26
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

MYO15_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.013124 (rank : 106)
Query Neighborhood Hits	112	Target Neighborhood Hits	671	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NCOA2_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.011525 (rank : 111)
Query Neighborhood Hits	112	Target Neighborhood Hits	281	Shared Neighborhood Hits	18
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

PVRL1_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.004926 (rank : 124)
Query Neighborhood Hits	112	Target Neighborhood Hits	219	Shared Neighborhood Hits	2
SwissProt Accessions	Q15223, O75465, Q9HBE6, Q9HBW2	Gene names	PVRL1, HVEC, PRR1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (Herpesvirus Ig-like receptor) (HIgR) (CD111 antigen).

RPGF2_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.009267 (rank : 117)
Query Neighborhood Hits	112	Target Neighborhood Hits	242	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

TBCD1_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.023155 (rank : 89)
Query Neighborhood Hits	112	Target Neighborhood Hits	276	Shared Neighborhood Hits	10
SwissProt Accessions	Q86TI0, Q96K82, Q9UPP4	Gene names	TBC1D1, KIAA1108
Domain Architecture
Description	TBC1 domain family member 1.

TBCD4_MOUSE
θ value	8.99809 (rank : 112)	NC score	0.028514 (rank : 83)
Query Neighborhood Hits	112	Target Neighborhood Hits	276	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

BSN_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.058004 (rank : 37)
Query Neighborhood Hits	112	Target Neighborhood Hits	2057	Shared Neighborhood Hits	64
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CDN1C_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.075060 (rank : 25)
Query Neighborhood Hits	112	Target Neighborhood Hits	168	Shared Neighborhood Hits	16
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

FA43B_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.065991 (rank : 29)
Query Neighborhood Hits	112	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZT52	Gene names	FAM43B
Domain Architecture	No domain graphic available
Description	Protein FAM43B.

JIP2_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.054294 (rank : 45)
Query Neighborhood Hits	112	Target Neighborhood Hits	288	Shared Neighborhood Hits	13
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

JIP2_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.052371 (rank : 50)
Query Neighborhood Hits	112	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

MLL3_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.058027 (rank : 36)
Query Neighborhood Hits	112	Target Neighborhood Hits	1644	Shared Neighborhood Hits	59
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

NACAM_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.052779 (rank : 48)
Query Neighborhood Hits	112	Target Neighborhood Hits	1866	Shared Neighborhood Hits	73
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PRR12_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.056161 (rank : 42)
Query Neighborhood Hits	112	Target Neighborhood Hits	460	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PRR13_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.053253 (rank : 47)
Query Neighborhood Hits	112	Target Neighborhood Hits	105	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

RAPH1_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.060343 (rank : 34)
Query Neighborhood Hits	112	Target Neighborhood Hits	593	Shared Neighborhood Hits	35
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

SF3A2_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.051346 (rank : 51)
Query Neighborhood Hits	112	Target Neighborhood Hits	263	Shared Neighborhood Hits	23
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

WASL_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.050163 (rank : 54)
Query Neighborhood Hits	112	Target Neighborhood Hits	312	Shared Neighborhood Hits	27
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

YLPM1_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.058907 (rank : 35)
Query Neighborhood Hits	112	Target Neighborhood Hits	505	Shared Neighborhood Hits	25
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ZN207_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.080909 (rank : 23)
Query Neighborhood Hits	112	Target Neighborhood Hits	326	Shared Neighborhood Hits	17
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

Hits sorted by NC score

NUMB_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	112	Target Neighborhood Hits	112	Shared Neighborhood Hits	112
SwissProt Accessions	P49757, Q6NUQ7, Q86SY1, Q8WW73, Q9UBG1, Q9UEQ4, Q9UKE8, Q9UKE9, Q9UKF0, Q9UQJ4	Gene names	NUMB
Domain Architecture
Description	Protein numb homolog (h-Numb) (Protein S171).

NUMB_MOUSE
NC score	0.983232 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	112	Target Neighborhood Hits	91	Shared Neighborhood Hits	48
SwissProt Accessions	Q9QZS3, P70422, Q8CIB1, Q9DC57, Q9QZR1, Q9QZS4	Gene names	Numb
Domain Architecture
Description	Protein numb homolog (m-Numb) (m-Nb).

NUMBL_MOUSE
NC score	0.937837 (rank : 3)	θ value	8.0589e-150 (rank : 4)
Query Neighborhood Hits	112	Target Neighborhood Hits	147	Shared Neighborhood Hits	30
SwissProt Accessions	O08919, Q6NVG8	Gene names	Numbl, Nbl
Domain Architecture
Description	Numb-like protein.

NUMBL_HUMAN
NC score	0.850814 (rank : 4)	θ value	6.17048e-150 (rank : 3)
Query Neighborhood Hits	112	Target Neighborhood Hits	394	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

ARH_HUMAN
NC score	0.588098 (rank : 5)	θ value	3.18553e-13 (rank : 5)
Query Neighborhood Hits	112	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	Q5SW96, Q6TQS9, Q8N2Y0, Q9UFI9	Gene names	LDLRAP1, ARH
Domain Architecture	No domain graphic available
Description	Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein).

ARH_MOUSE
NC score	0.576376 (rank : 6)	θ value	1.33837e-11 (rank : 6)
Query Neighborhood Hits	112	Target Neighborhood Hits	32	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C142, Q6NWV6, Q8VDQ0	Gene names	Ldlrap1, Arh
Domain Architecture	No domain graphic available
Description	Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein homolog).

DAB1_MOUSE
NC score	0.397747 (rank : 7)	θ value	1.53129e-07 (rank : 8)
Query Neighborhood Hits	112	Target Neighborhood Hits	145	Shared Neighborhood Hits	25
SwissProt Accessions	P97318, P97316, P97317	Gene names	Dab1
Domain Architecture
Description	Disabled homolog 1.

DAB1_HUMAN
NC score	0.390019 (rank : 8)	θ value	1.53129e-07 (rank : 7)
Query Neighborhood Hits	112	Target Neighborhood Hits	219	Shared Neighborhood Hits	36
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

CAPON_HUMAN
NC score	0.351611 (rank : 9)	θ value	0.000121331 (rank : 13)
Query Neighborhood Hits	112	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	O75052, O43564	Gene names	NOS1AP, CAPON, KIAA0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).

CAPON_MOUSE
NC score	0.340742 (rank : 10)	θ value	0.00020696 (rank : 14)
Query Neighborhood Hits	112	Target Neighborhood Hits	34	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D3A8, Q80TZ6	Gene names	Nos1ap, Capon, Kiaa0464
Domain Architecture	No domain graphic available
Description	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C--terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein).

DAB2_HUMAN
NC score	0.337659 (rank : 11)	θ value	5.44631e-05 (rank : 12)
Query Neighborhood Hits	112	Target Neighborhood Hits	197	Shared Neighborhood Hits	33
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

DAB2_MOUSE
NC score	0.334251 (rank : 12)	θ value	4.1701e-05 (rank : 11)
Query Neighborhood Hits	112	Target Neighborhood Hits	163	Shared Neighborhood Hits	25
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

JIP1_MOUSE
NC score	0.213535 (rank : 13)	θ value	0.00298849 (rank : 15)
Query Neighborhood Hits	112	Target Neighborhood Hits	259	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JIP1_HUMAN
NC score	0.203664 (rank : 14)	θ value	0.00665767 (rank : 16)
Query Neighborhood Hits	112	Target Neighborhood Hits	271	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

FA43A_HUMAN
NC score	0.200841 (rank : 15)	θ value	0.0961366 (rank : 24)
Query Neighborhood Hits	112	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N2R8, Q8IXP4, Q8WZ07	Gene names	FAM43A
Domain Architecture	No domain graphic available
Description	Protein FAM43A.

FA43A_MOUSE
NC score	0.200742 (rank : 16)	θ value	0.0961366 (rank : 25)
Query Neighborhood Hits	112	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BUP8, Q8R231	Gene names	Fam43a
Domain Architecture	No domain graphic available
Description	Protein FAM43A.

ANKS1_MOUSE
NC score	0.165522 (rank : 17)	θ value	3.41135e-07 (rank : 10)
Query Neighborhood Hits	112	Target Neighborhood Hits	453	Shared Neighborhood Hits	27
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ANKS1_HUMAN
NC score	0.157028 (rank : 18)	θ value	3.41135e-07 (rank : 9)
Query Neighborhood Hits	112	Target Neighborhood Hits	438	Shared Neighborhood Hits	24
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

APBB2_HUMAN
NC score	0.122400 (rank : 19)	θ value	0.0431538 (rank : 21)
Query Neighborhood Hits	112	Target Neighborhood Hits	96	Shared Neighborhood Hits	19
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

SHC2_MOUSE
NC score	0.110911 (rank : 20)	θ value	0.00869519 (rank : 17)
Query Neighborhood Hits	112	Target Neighborhood Hits	144	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

SHC2_HUMAN
NC score	0.107710 (rank : 21)	θ value	0.0113563 (rank : 18)
Query Neighborhood Hits	112	Target Neighborhood Hits	170	Shared Neighborhood Hits	13
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

APBB2_MOUSE
NC score	0.097242 (rank : 22)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	112	Target Neighborhood Hits	88	Shared Neighborhood Hits	18
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

ZN207_HUMAN
NC score	0.080909 (rank : 23)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	112	Target Neighborhood Hits	326	Shared Neighborhood Hits	17
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

CN032_HUMAN
NC score	0.076326 (rank : 24)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	112	Target Neighborhood Hits	267	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CDN1C_HUMAN
NC score	0.075060 (rank : 25)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	112	Target Neighborhood Hits	168	Shared Neighborhood Hits	16
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CN032_MOUSE
NC score	0.072236 (rank : 26)	θ value	1.06291 (rank : 43)
Query Neighborhood Hits	112	Target Neighborhood Hits	233	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

APBB1_MOUSE
NC score	0.071348 (rank : 27)	θ value	0.813845 (rank : 36)
Query Neighborhood Hits	112	Target Neighborhood Hits	75	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QXJ1, O08642, Q3TPU0, Q8BNF4, Q8BSR9	Gene names	Apbb1, Fe65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

TAF4_HUMAN
NC score	0.066998 (rank : 28)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	112	Target Neighborhood Hits	687	Shared Neighborhood Hits	39
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

FA43B_HUMAN
NC score	0.065991 (rank : 29)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	112	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZT52	Gene names	FAM43B
Domain Architecture	No domain graphic available
Description	Protein FAM43B.

APBB1_HUMAN
NC score	0.065290 (rank : 30)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	112	Target Neighborhood Hits	62	Shared Neighborhood Hits	15
SwissProt Accessions	O00213, Q96A93	Gene names	APBB1, FE65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

CBP_MOUSE
NC score	0.064535 (rank : 31)	θ value	0.47712 (rank : 30)
Query Neighborhood Hits	112	Target Neighborhood Hits	1051	Shared Neighborhood Hits	61
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

TM108_MOUSE
NC score	0.062510 (rank : 32)	θ value	0.125558 (rank : 26)
Query Neighborhood Hits	112	Target Neighborhood Hits	336	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

PDC6I_MOUSE
NC score	0.060421 (rank : 33)	θ value	0.813845 (rank : 38)
Query Neighborhood Hits	112	Target Neighborhood Hits	275	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

RAPH1_HUMAN
NC score	0.060343 (rank : 34)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	112	Target Neighborhood Hits	593	Shared Neighborhood Hits	35
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

YLPM1_MOUSE
NC score	0.058907 (rank : 35)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	112	Target Neighborhood Hits	505	Shared Neighborhood Hits	25
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

MLL3_HUMAN
NC score	0.058027 (rank : 36)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	112	Target Neighborhood Hits	1644	Shared Neighborhood Hits	59
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

BSN_MOUSE
NC score	0.058004 (rank : 37)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	112	Target Neighborhood Hits	2057	Shared Neighborhood Hits	64
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CJ012_HUMAN
NC score	0.056768 (rank : 38)	θ value	1.06291 (rank : 42)
Query Neighborhood Hits	112	Target Neighborhood Hits	467	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

BSN_HUMAN
NC score	0.056732 (rank : 39)	θ value	0.279714 (rank : 27)
Query Neighborhood Hits	112	Target Neighborhood Hits	1537	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

FMN2_MOUSE
NC score	0.056324 (rank : 40)	θ value	2.36792 (rank : 63)
Query Neighborhood Hits	112	Target Neighborhood Hits	349	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

PCLO_HUMAN
NC score	0.056206 (rank : 41)	θ value	0.365318 (rank : 29)
Query Neighborhood Hits	112	Target Neighborhood Hits	2046	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PRR12_HUMAN
NC score	0.056161 (rank : 42)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	112	Target Neighborhood Hits	460	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

ATN1_HUMAN
NC score	0.055693 (rank : 43)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	112	Target Neighborhood Hits	676	Shared Neighborhood Hits	40
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

MUC7_HUMAN
NC score	0.055298 (rank : 44)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	112	Target Neighborhood Hits	538	Shared Neighborhood Hits	36
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

JIP2_HUMAN
NC score	0.054294 (rank : 45)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	112	Target Neighborhood Hits	288	Shared Neighborhood Hits	13
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

PER2_MOUSE
NC score	0.054284 (rank : 46)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	112	Target Neighborhood Hits	325	Shared Neighborhood Hits	31
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

PRR13_HUMAN
NC score	0.053253 (rank : 47)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	112	Target Neighborhood Hits	105	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

NACAM_MOUSE
NC score	0.052779 (rank : 48)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	112	Target Neighborhood Hits	1866	Shared Neighborhood Hits	73
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

RERE_HUMAN
NC score	0.052453 (rank : 49)	θ value	0.813845 (rank : 39)
Query Neighborhood Hits	112	Target Neighborhood Hits	779	Shared Neighborhood Hits	42
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

JIP2_MOUSE
NC score	0.052371 (rank : 50)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	112	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

SF3A2_HUMAN
NC score	0.051346 (rank : 51)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	112	Target Neighborhood Hits	263	Shared Neighborhood Hits	23
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

MISS_MOUSE
NC score	0.050498 (rank : 52)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	112	Target Neighborhood Hits	444	Shared Neighborhood Hits	36
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

CBP_HUMAN
NC score	0.050309 (rank : 53)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	112	Target Neighborhood Hits	941	Shared Neighborhood Hits	54
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

WASL_HUMAN
NC score	0.050163 (rank : 54)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	112	Target Neighborhood Hits	312	Shared Neighborhood Hits	27
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

ENAH_MOUSE
NC score	0.047602 (rank : 55)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	112	Target Neighborhood Hits	919	Shared Neighborhood Hits	38
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

SRRM2_MOUSE
NC score	0.047536 (rank : 56)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	112	Target Neighborhood Hits	1470	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

MLL3_MOUSE
NC score	0.045956 (rank : 57)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	112	Target Neighborhood Hits	1399	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NU214_HUMAN
NC score	0.044443 (rank : 58)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	112	Target Neighborhood Hits	657	Shared Neighborhood Hits	34
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

ARI1B_HUMAN
NC score	0.042647 (rank : 59)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	112	Target Neighborhood Hits	567	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

TCRG1_MOUSE
NC score	0.042296 (rank : 60)	θ value	0.62314 (rank : 35)
Query Neighborhood Hits	112	Target Neighborhood Hits	947	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

DIDO1_HUMAN
NC score	0.041291 (rank : 61)	θ value	1.06291 (rank : 44)
Query Neighborhood Hits	112	Target Neighborhood Hits	960	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

TCRG1_HUMAN
NC score	0.040992 (rank : 62)	θ value	1.06291 (rank : 46)
Query Neighborhood Hits	112	Target Neighborhood Hits	929	Shared Neighborhood Hits	30
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

HNF1A_HUMAN
NC score	0.040799 (rank : 63)	θ value	0.47712 (rank : 31)
Query Neighborhood Hits	112	Target Neighborhood Hits	193	Shared Neighborhood Hits	12
SwissProt Accessions	P20823, Q99861	Gene names	TCF1, HNF1A
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1).

CK024_MOUSE
NC score	0.040625 (rank : 64)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	112	Target Neighborhood Hits	307	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

HNF1A_MOUSE
NC score	0.038732 (rank : 65)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	112	Target Neighborhood Hits	212	Shared Neighborhood Hits	17
SwissProt Accessions	P22361	Gene names	Tcf1, Hnf-1, Hnf-1a, Hnf1a
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1).

ANX11_MOUSE
NC score	0.038691 (rank : 66)	θ value	0.0563607 (rank : 23)
Query Neighborhood Hits	112	Target Neighborhood Hits	200	Shared Neighborhood Hits	18
SwissProt Accessions	P97384	Gene names	Anxa11, Anx11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50).

MILK1_MOUSE
NC score	0.038505 (rank : 67)	θ value	0.0330416 (rank : 20)
Query Neighborhood Hits	112	Target Neighborhood Hits	788	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

SMRC2_MOUSE
NC score	0.037596 (rank : 68)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	112	Target Neighborhood Hits	487	Shared Neighborhood Hits	22
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

T22D2_HUMAN
NC score	0.037201 (rank : 69)	θ value	0.813845 (rank : 40)
Query Neighborhood Hits	112	Target Neighborhood Hits	250	Shared Neighborhood Hits	19
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

PCLO_MOUSE
NC score	0.037140 (rank : 70)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	112	Target Neighborhood Hits	2275	Shared Neighborhood Hits	63
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PER3_HUMAN
NC score	0.036783 (rank : 71)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	112	Target Neighborhood Hits	479	Shared Neighborhood Hits	38
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

TARA_HUMAN
NC score	0.036569 (rank : 72)	θ value	0.813845 (rank : 41)
Query Neighborhood Hits	112	Target Neighborhood Hits	1626	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

PHF2_MOUSE
NC score	0.035188 (rank : 73)	θ value	0.0431538 (rank : 22)
Query Neighborhood Hits	112	Target Neighborhood Hits	241	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

ZN750_MOUSE
NC score	0.034974 (rank : 74)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	112	Target Neighborhood Hits	346	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

CS016_HUMAN
NC score	0.034950 (rank : 75)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	112	Target Neighborhood Hits	310	Shared Neighborhood Hits	20
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

CT174_HUMAN
NC score	0.033956 (rank : 76)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	112	Target Neighborhood Hits	181	Shared Neighborhood Hits	12
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

FUBP2_HUMAN
NC score	0.033425 (rank : 77)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	112	Target Neighborhood Hits	145	Shared Neighborhood Hits	11
SwissProt Accessions	Q92945, O00301, Q9UNT5, Q9UQH5	Gene names	KHSRP, FUBP2
Domain Architecture
Description	Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75).

ZIM10_HUMAN
NC score	0.033238 (rank : 78)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	112	Target Neighborhood Hits	577	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

MUC2_HUMAN
NC score	0.033116 (rank : 79)	θ value	0.47712 (rank : 32)
Query Neighborhood Hits	112	Target Neighborhood Hits	906	Shared Neighborhood Hits	35
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

CXXC6_HUMAN
NC score	0.032783 (rank : 80)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	112	Target Neighborhood Hits	180	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

FBX43_HUMAN
NC score	0.032452 (rank : 81)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	112	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q4G163	Gene names	FBXO43, EMI2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

PO121_MOUSE
NC score	0.028694 (rank : 82)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	112	Target Neighborhood Hits	345	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

TBCD4_MOUSE
NC score	0.028514 (rank : 83)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	112	Target Neighborhood Hits	276	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

TBCD4_HUMAN
NC score	0.027875 (rank : 84)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	112	Target Neighborhood Hits	357	Shared Neighborhood Hits	13
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

RD23B_MOUSE
NC score	0.026831 (rank : 85)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	112	Target Neighborhood Hits	189	Shared Neighborhood Hits	17
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

NOTC2_MOUSE
NC score	0.026092 (rank : 86)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	112	Target Neighborhood Hits	1069	Shared Neighborhood Hits	29
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_HUMAN
NC score	0.024513 (rank : 87)	θ value	0.279714 (rank : 28)
Query Neighborhood Hits	112	Target Neighborhood Hits	1113	Shared Neighborhood Hits	36
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CNOT3_HUMAN
NC score	0.023392 (rank : 88)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	112	Target Neighborhood Hits	425	Shared Neighborhood Hits	19
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

TBCD1_HUMAN
NC score	0.023155 (rank : 89)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	112	Target Neighborhood Hits	276	Shared Neighborhood Hits	10
SwissProt Accessions	Q86TI0, Q96K82, Q9UPP4	Gene names	TBC1D1, KIAA1108
Domain Architecture
Description	TBC1 domain family member 1.

R3HD1_HUMAN
NC score	0.022350 (rank : 90)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	112	Target Neighborhood Hits	203	Shared Neighborhood Hits	16
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

SH22A_MOUSE
NC score	0.021794 (rank : 91)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	112	Target Neighborhood Hits	179	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

PI4KB_HUMAN
NC score	0.021271 (rank : 92)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	112	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBF8, O15096, P78405, Q9BWR6	Gene names	PIK4CB, PI4KB
Domain Architecture
Description	Phosphatidylinositol 4-kinase beta (EC 2.7.1.67) (PtdIns 4-kinase beta) (PI4Kbeta) (PI4K-beta) (NPIK) (PI4K92).

LDB3_MOUSE
NC score	0.020473 (rank : 93)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	112	Target Neighborhood Hits	510	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

PRKN2_HUMAN
NC score	0.019981 (rank : 94)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	112	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	O60260, Q5TFV8, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07	Gene names	PARK2, PRKN
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2).

SEPT9_HUMAN
NC score	0.019844 (rank : 95)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	112	Target Neighborhood Hits	706	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

MCM3A_HUMAN
NC score	0.019500 (rank : 96)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	112	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	O60318, Q9UMT4	Gene names	MCM3AP, GANP, KIAA0572, MAP80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

DOK2_MOUSE
NC score	0.018975 (rank : 97)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	112	Target Neighborhood Hits	244	Shared Neighborhood Hits	17
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

BORG5_HUMAN
NC score	0.017783 (rank : 98)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	112	Target Neighborhood Hits	135	Shared Neighborhood Hits	11
SwissProt Accessions	Q00587, Q96GN1	Gene names	CDC42EP1, BORG5, CEP1, MSE55
Domain Architecture
Description	Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55).

AAK1_MOUSE
NC score	0.017509 (rank : 99)	θ value	0.0193708 (rank : 19)
Query Neighborhood Hits	112	Target Neighborhood Hits	1051	Shared Neighborhood Hits	27
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

DTX2_MOUSE
NC score	0.016849 (rank : 100)	θ value	2.36792 (rank : 62)
Query Neighborhood Hits	112	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3P2, Q9CZV3, Q9ER07, Q9ER08	Gene names	Dtx2
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (mDTX2).

GSLG1_MOUSE
NC score	0.016667 (rank : 101)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	112	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q61543, Q9QZ40	Gene names	Glg1, Esl1, Mg160, Selel
Domain Architecture
Description	Golgi apparatus protein 1 precursor (Golgi sialoglycoprotein MG-160) (E-selectin ligand 1) (ESL-1) (Selel).

PO6F2_HUMAN
NC score	0.015642 (rank : 102)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	112	Target Neighborhood Hits	618	Shared Neighborhood Hits	24
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

TEAD1_HUMAN
NC score	0.015289 (rank : 103)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	112	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P28347	Gene names	TEAD1, TCF13, TEF1
Domain Architecture
Description	Transcriptional enhancer factor TEF-1 (TEA domain family member 1) (TEAD-1) (Protein GT-IIC) (Transcription factor 13) (NTEF-1).

ADA29_HUMAN
NC score	0.014566 (rank : 104)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	112	Target Neighborhood Hits	247	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

RIMB1_HUMAN
NC score	0.014345 (rank : 105)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	112	Target Neighborhood Hits	1479	Shared Neighborhood Hits	32
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

MYO15_HUMAN
NC score	0.013124 (rank : 106)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	112	Target Neighborhood Hits	671	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

TEAD1_MOUSE
NC score	0.013017 (rank : 107)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	112	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	P30051	Gene names	Tead1, Tcf13, Tef-1, Tef1
Domain Architecture
Description	Transcriptional enhancer factor TEF-1 (TEA domain family member 1) (TEAD-1) (Protein GT-IIC) (Transcription factor 13) (NTEF-1).

BPIL3_MOUSE
NC score	0.012956 (rank : 108)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	112	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BU51, Q80ZU8	Gene names	Bpil3
Domain Architecture
Description	Bactericidal/permeability-increasing protein-like 3 precursor.

MAGC1_HUMAN
NC score	0.012850 (rank : 109)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	112	Target Neighborhood Hits	431	Shared Neighborhood Hits	21
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

B3A2_HUMAN
NC score	0.012133 (rank : 110)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	112	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	P04920, Q45EY5, Q969L3	Gene names	SLC4A2, AE2, EPB3L1, HKB3, MPB3L
Domain Architecture
Description	Anion exchange protein 2 (Non-erythroid band 3-like protein) (AE2 anion exchanger) (Solute carrier family 4 member 2) (BND3L).

NCOA2_HUMAN
NC score	0.011525 (rank : 111)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	112	Target Neighborhood Hits	281	Shared Neighborhood Hits	18
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

SREC_HUMAN
NC score	0.011435 (rank : 112)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	112	Target Neighborhood Hits	645	Shared Neighborhood Hits	9
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

GGA2_HUMAN
NC score	0.011349 (rank : 113)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	112	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

PLXB1_HUMAN
NC score	0.011187 (rank : 114)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	112	Target Neighborhood Hits	360	Shared Neighborhood Hits	25
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

PXDC2_MOUSE
NC score	0.010826 (rank : 115)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	112	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DC11, Q6PET5, Q91ZV6	Gene names	Plxdc2, Tem7r
Domain Architecture	No domain graphic available
Description	Plexin domain-containing protein 2 precursor (Tumor endothelial marker 7-related protein).

PDLI5_HUMAN
NC score	0.009585 (rank : 116)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	112	Target Neighborhood Hits	322	Shared Neighborhood Hits	11
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

RPGF2_HUMAN
NC score	0.009267 (rank : 117)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	112	Target Neighborhood Hits	242	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

ITSN1_HUMAN
NC score	0.009226 (rank : 118)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	112	Target Neighborhood Hits	1757	Shared Neighborhood Hits	29
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

WWP1_MOUSE
NC score	0.008409 (rank : 119)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	112	Target Neighborhood Hits	138	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

TLN2_HUMAN
NC score	0.007741 (rank : 120)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	112	Target Neighborhood Hits	157	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

HXA3_HUMAN
NC score	0.007224 (rank : 121)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	112	Target Neighborhood Hits	535	Shared Neighborhood Hits	21
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

HXD12_HUMAN
NC score	0.006648 (rank : 122)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	112	Target Neighborhood Hits	334	Shared Neighborhood Hits	5
SwissProt Accessions	P35452, Q9NS03	Gene names	HOXD12, HOX4H
Domain Architecture
Description	Homeobox protein Hox-D12 (Hox-4H).

SN1L1_HUMAN
NC score	0.005383 (rank : 123)	θ value	0.47712 (rank : 33)
Query Neighborhood Hits	112	Target Neighborhood Hits	911	Shared Neighborhood Hits	9
SwissProt Accessions	P57059, Q5R2V5, Q86YJ2	Gene names	SNF1LK
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK).

PVRL1_HUMAN
NC score	0.004926 (rank : 124)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	112	Target Neighborhood Hits	219	Shared Neighborhood Hits	2
SwissProt Accessions	Q15223, O75465, Q9HBE6, Q9HBW2	Gene names	PVRL1, HVEC, PRR1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (Herpesvirus Ig-like receptor) (HIgR) (CD111 antigen).

MK07_HUMAN
NC score	0.004458 (rank : 125)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	112	Target Neighborhood Hits	1087	Shared Neighborhood Hits	26
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

GBX1_HUMAN
NC score	0.003320 (rank : 126)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	112	Target Neighborhood Hits	334	Shared Neighborhood Hits	8
SwissProt Accessions	Q14549	Gene names	GBX1
Domain Architecture	No domain graphic available
Description	Homeobox protein GBX-1 (Gastrulation and brain-specific homeobox protein 1).