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Network neighborhood for query Sequence : FBX43_HUMAN

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FBX43_HUMAN
SwissProt Accessions	Q4G163	Gene names	FBXO43, EMI2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FBX43_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	Q4G163	Gene names	FBXO43, EMI2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

FBX43_MOUSE
θ value	0 (rank : 2)	NC score	0.982421 (rank : 2)
Query Neighborhood Hits	34	Target Neighborhood Hits	40	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CDI2, Q4G0C8, Q8R0R1	Gene names	Fbxo43, Emi2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

FBX5_HUMAN
θ value	1.32909e-35 (rank : 3)	NC score	0.774926 (rank : 3)
Query Neighborhood Hits	34	Target Neighborhood Hits	29	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKT4, Q8WV29, Q9UGC8	Gene names	FBXO5, EMI1, FBX5
Domain Architecture	No domain graphic available
Description	F-box only protein 5 (Early mitotic inhibitor 1).

RNF14_HUMAN
θ value	5.44631e-05 (rank : 4)	NC score	0.203968 (rank : 4)
Query Neighborhood Hits	34	Target Neighborhood Hits	70	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UBS8, O94793, Q6IBV0	Gene names	RNF14, ARA54
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein) (HFB30).

RNF14_MOUSE
θ value	0.00020696 (rank : 5)	NC score	0.196312 (rank : 5)
Query Neighborhood Hits	34	Target Neighborhood Hits	69	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JI90, Q9D0L2, Q9D6N2, Q9D6Z8, Q9JI89	Gene names	Rnf14, Ara54, Triad2
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein).

RNF19_HUMAN
θ value	0.365318 (rank : 6)	NC score	0.112615 (rank : 7)
Query Neighborhood Hits	34	Target Neighborhood Hits	105	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

RNF19_MOUSE
θ value	0.365318 (rank : 7)	NC score	0.112945 (rank : 6)
Query Neighborhood Hits	34	Target Neighborhood Hits	96	Shared Neighborhood Hits	10
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

ANLN_HUMAN
θ value	0.62314 (rank : 8)	NC score	0.039984 (rank : 17)
Query Neighborhood Hits	34	Target Neighborhood Hits	222	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

IBRD3_HUMAN
θ value	0.62314 (rank : 9)	NC score	0.108273 (rank : 8)
Query Neighborhood Hits	34	Target Neighborhood Hits	70	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZMZ0, Q6P6A4	Gene names	IBRDC3
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 3.

BUB1B_MOUSE
θ value	0.813845 (rank : 10)	NC score	0.038371 (rank : 18)
Query Neighborhood Hits	34	Target Neighborhood Hits	202	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z1S0	Gene names	Bub1b, Mad3l
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L).

NUMB_HUMAN
θ value	0.813845 (rank : 11)	NC score	0.032452 (rank : 19)
Query Neighborhood Hits	34	Target Neighborhood Hits	112	Shared Neighborhood Hits	4
SwissProt Accessions	P49757, Q6NUQ7, Q86SY1, Q8WW73, Q9UBG1, Q9UEQ4, Q9UKE8, Q9UKE9, Q9UKF0, Q9UQJ4	Gene names	NUMB
Domain Architecture
Description	Protein numb homolog (h-Numb) (Protein S171).

FBW1B_HUMAN
θ value	1.06291 (rank : 12)	NC score	0.023465 (rank : 21)
Query Neighborhood Hits	34	Target Neighborhood Hits	327	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKB1, Q9P2S8, Q9P2S9, Q9Y4C6	Gene names	FBXW11, BTRCP2, FBW1B, FBXW1B, KIAA0696
Domain Architecture
Description	F-box/WD repeat protein 11 (F-box/WD repeat protein 1B) (F-box and WD repeats protein beta-TrCP2).

FBW1A_HUMAN
θ value	1.38821 (rank : 13)	NC score	0.023092 (rank : 22)
Query Neighborhood Hits	34	Target Neighborhood Hits	329	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y297, Q9Y213	Gene names	BTRC, BTRCP, FBW1A, FBXW1A
Domain Architecture
Description	F-box/WD repeat protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit).

BRAP_MOUSE
θ value	3.0926 (rank : 14)	NC score	0.019940 (rank : 23)
Query Neighborhood Hits	34	Target Neighborhood Hits	409	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

CCD91_MOUSE
θ value	3.0926 (rank : 15)	NC score	0.013968 (rank : 28)
Query Neighborhood Hits	34	Target Neighborhood Hits	699	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

DGKK_HUMAN
θ value	3.0926 (rank : 16)	NC score	0.016398 (rank : 26)
Query Neighborhood Hits	34	Target Neighborhood Hits	378	Shared Neighborhood Hits	3
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

FA98A_HUMAN
θ value	3.0926 (rank : 17)	NC score	0.024081 (rank : 20)
Query Neighborhood Hits	34	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NCA5	Gene names	FAM98A
Domain Architecture	No domain graphic available
Description	Protein FAM98A.

PRKN2_HUMAN
θ value	4.03905 (rank : 18)	NC score	0.090536 (rank : 9)
Query Neighborhood Hits	34	Target Neighborhood Hits	65	Shared Neighborhood Hits	11
SwissProt Accessions	O60260, Q5TFV8, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07	Gene names	PARK2, PRKN
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2).

WEE1_HUMAN
θ value	4.03905 (rank : 19)	NC score	0.006923 (rank : 37)
Query Neighborhood Hits	34	Target Neighborhood Hits	777	Shared Neighborhood Hits	3
SwissProt Accessions	P30291	Gene names	WEE1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase) (WEE1hu).

AL3B1_HUMAN
θ value	5.27518 (rank : 20)	NC score	0.010348 (rank : 31)
Query Neighborhood Hits	34	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	P43353, Q53XL5, Q8N515, Q96CK8	Gene names	ALDH3B1, ALDH7
Domain Architecture
Description	Aldehyde dehydrogenase 3B1 (EC 1.2.1.5) (Aldehyde dehydrogenase 7).

PCLO_MOUSE
θ value	5.27518 (rank : 21)	NC score	0.007904 (rank : 36)
Query Neighborhood Hits	34	Target Neighborhood Hits	2275	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PRKN2_MOUSE
θ value	5.27518 (rank : 22)	NC score	0.088649 (rank : 10)
Query Neighborhood Hits	34	Target Neighborhood Hits	69	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WVS6, Q9ES22, Q9ES23	Gene names	Park2, Prkn
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN).

RUFY2_HUMAN
θ value	5.27518 (rank : 23)	NC score	0.004716 (rank : 40)
Query Neighborhood Hits	34	Target Neighborhood Hits	1208	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

SH24A_HUMAN
θ value	5.27518 (rank : 24)	NC score	0.014730 (rank : 27)
Query Neighborhood Hits	34	Target Neighborhood Hits	455	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7	Gene names	SH2D4A, SH2A
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A (Protein SH(2)A).

AT11B_HUMAN
θ value	6.88961 (rank : 25)	NC score	0.006508 (rank : 38)
Query Neighborhood Hits	34	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2G3, Q96FN1, Q9UKK7	Gene names	ATP11B, ATPIF, ATPIR, KIAA0956
Domain Architecture
Description	Probable phospholipid-transporting ATPase IF (EC 3.6.3.1) (ATPase class I type 11B) (ATPase IR).

H15_MOUSE
θ value	6.88961 (rank : 26)	NC score	0.012803 (rank : 29)
Query Neighborhood Hits	34	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	P43276, Q9CRM8	Gene names	Hist1h1b, H1f5
Domain Architecture
Description	Histone H1.5 (H1 VAR.5) (H1b).

K0406_HUMAN
θ value	6.88961 (rank : 27)	NC score	0.017353 (rank : 25)
Query Neighborhood Hits	34	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	O43156, Q5JX67, Q96A38, Q9BR47, Q9H4K0	Gene names	KIAA0406
Domain Architecture	No domain graphic available
Description	Protein KIAA0406.

ANXA7_HUMAN
θ value	8.99809 (rank : 28)	NC score	0.008224 (rank : 35)
Query Neighborhood Hits	34	Target Neighborhood Hits	168	Shared Neighborhood Hits	3
SwissProt Accessions	P20073	Gene names	ANXA7, ANX7, SNX
Domain Architecture
Description	Annexin A7 (Annexin VII) (Synexin).

ANXA7_MOUSE
θ value	8.99809 (rank : 29)	NC score	0.008435 (rank : 34)
Query Neighborhood Hits	34	Target Neighborhood Hits	142	Shared Neighborhood Hits	4
SwissProt Accessions	Q07076	Gene names	Anxa7, Anx7
Domain Architecture
Description	Annexin A7 (Annexin VII) (Synexin).

CA049_MOUSE
θ value	8.99809 (rank : 30)	NC score	0.017635 (rank : 24)
Query Neighborhood Hits	34	Target Neighborhood Hits	121	Shared Neighborhood Hits	2
SwissProt Accessions	Q14BK3, Q4KKY9, Q9D9J9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf49 homolog.

JHD2A_MOUSE
θ value	8.99809 (rank : 31)	NC score	0.008462 (rank : 33)
Query Neighborhood Hits	34	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PCM1, Q2MJQ6, Q3TKW8, Q3UML3, Q6ZQ57, Q8K2J6, Q8K2K4, Q8R350	Gene names	Jmjd1a, Jhdm2a, Kiaa0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

OXR1_MOUSE
θ value	8.99809 (rank : 32)	NC score	0.010350 (rank : 30)
Query Neighborhood Hits	34	Target Neighborhood Hits	516	Shared Neighborhood Hits	5
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

SMAL1_HUMAN
θ value	8.99809 (rank : 33)	NC score	0.008773 (rank : 32)
Query Neighborhood Hits	34	Target Neighborhood Hits	174	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

WEE1_MOUSE
θ value	8.99809 (rank : 34)	NC score	0.005026 (rank : 39)
Query Neighborhood Hits	34	Target Neighborhood Hits	794	Shared Neighborhood Hits	3
SwissProt Accessions	P47810, Q9EPL7	Gene names	Wee1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase).

ARI2_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.054603 (rank : 11)
Query Neighborhood Hits	34	Target Neighborhood Hits	113	Shared Neighborhood Hits	9
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

ARI2_MOUSE
θ value	θ > 10 (rank : 36)	NC score	0.053270 (rank : 13)
Query Neighborhood Hits	34	Target Neighborhood Hits	106	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

IBRD2_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.054103 (rank : 12)
Query Neighborhood Hits	34	Target Neighborhood Hits	55	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z419, Q6P4Q0, Q8N3R7, Q9BX38	Gene names	IBRDC2, P53RFP
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2) (p53-inducible RING finger protein).

IBRD2_MOUSE
θ value	θ > 10 (rank : 38)	NC score	0.051159 (rank : 16)
Query Neighborhood Hits	34	Target Neighborhood Hits	46	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).

UB7I4_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.052109 (rank : 15)
Query Neighborhood Hits	34	Target Neighborhood Hits	54	Shared Neighborhood Hits	8
SwissProt Accessions	P50876	Gene names	RNF144, KIAA0161, UBCE7IP4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

UB7I4_MOUSE
θ value	θ > 10 (rank : 40)	NC score	0.052652 (rank : 14)
Query Neighborhood Hits	34	Target Neighborhood Hits	59	Shared Neighborhood Hits	8
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

Hits sorted by NC score

FBX43_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	Q4G163	Gene names	FBXO43, EMI2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

FBX43_MOUSE
NC score	0.982421 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	34	Target Neighborhood Hits	40	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CDI2, Q4G0C8, Q8R0R1	Gene names	Fbxo43, Emi2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

FBX5_HUMAN
NC score	0.774926 (rank : 3)	θ value	1.32909e-35 (rank : 3)
Query Neighborhood Hits	34	Target Neighborhood Hits	29	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKT4, Q8WV29, Q9UGC8	Gene names	FBXO5, EMI1, FBX5
Domain Architecture	No domain graphic available
Description	F-box only protein 5 (Early mitotic inhibitor 1).

RNF14_HUMAN
NC score	0.203968 (rank : 4)	θ value	5.44631e-05 (rank : 4)
Query Neighborhood Hits	34	Target Neighborhood Hits	70	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UBS8, O94793, Q6IBV0	Gene names	RNF14, ARA54
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein) (HFB30).

RNF14_MOUSE
NC score	0.196312 (rank : 5)	θ value	0.00020696 (rank : 5)
Query Neighborhood Hits	34	Target Neighborhood Hits	69	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JI90, Q9D0L2, Q9D6N2, Q9D6Z8, Q9JI89	Gene names	Rnf14, Ara54, Triad2
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein).

RNF19_MOUSE
NC score	0.112945 (rank : 6)	θ value	0.365318 (rank : 7)
Query Neighborhood Hits	34	Target Neighborhood Hits	96	Shared Neighborhood Hits	10
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

RNF19_HUMAN
NC score	0.112615 (rank : 7)	θ value	0.365318 (rank : 6)
Query Neighborhood Hits	34	Target Neighborhood Hits	105	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

IBRD3_HUMAN
NC score	0.108273 (rank : 8)	θ value	0.62314 (rank : 9)
Query Neighborhood Hits	34	Target Neighborhood Hits	70	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZMZ0, Q6P6A4	Gene names	IBRDC3
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 3.

PRKN2_HUMAN
NC score	0.090536 (rank : 9)	θ value	4.03905 (rank : 18)
Query Neighborhood Hits	34	Target Neighborhood Hits	65	Shared Neighborhood Hits	11
SwissProt Accessions	O60260, Q5TFV8, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07	Gene names	PARK2, PRKN
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2).

PRKN2_MOUSE
NC score	0.088649 (rank : 10)	θ value	5.27518 (rank : 22)
Query Neighborhood Hits	34	Target Neighborhood Hits	69	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WVS6, Q9ES22, Q9ES23	Gene names	Park2, Prkn
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN).

ARI2_HUMAN
NC score	0.054603 (rank : 11)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	34	Target Neighborhood Hits	113	Shared Neighborhood Hits	9
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

IBRD2_HUMAN
NC score	0.054103 (rank : 12)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	34	Target Neighborhood Hits	55	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z419, Q6P4Q0, Q8N3R7, Q9BX38	Gene names	IBRDC2, P53RFP
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2) (p53-inducible RING finger protein).

ARI2_MOUSE
NC score	0.053270 (rank : 13)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	34	Target Neighborhood Hits	106	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

UB7I4_MOUSE
NC score	0.052652 (rank : 14)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	34	Target Neighborhood Hits	59	Shared Neighborhood Hits	8
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

UB7I4_HUMAN
NC score	0.052109 (rank : 15)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	34	Target Neighborhood Hits	54	Shared Neighborhood Hits	8
SwissProt Accessions	P50876	Gene names	RNF144, KIAA0161, UBCE7IP4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

IBRD2_MOUSE
NC score	0.051159 (rank : 16)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	34	Target Neighborhood Hits	46	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).

ANLN_HUMAN
NC score	0.039984 (rank : 17)	θ value	0.62314 (rank : 8)
Query Neighborhood Hits	34	Target Neighborhood Hits	222	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

BUB1B_MOUSE
NC score	0.038371 (rank : 18)	θ value	0.813845 (rank : 10)
Query Neighborhood Hits	34	Target Neighborhood Hits	202	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z1S0	Gene names	Bub1b, Mad3l
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L).

NUMB_HUMAN
NC score	0.032452 (rank : 19)	θ value	0.813845 (rank : 11)
Query Neighborhood Hits	34	Target Neighborhood Hits	112	Shared Neighborhood Hits	4
SwissProt Accessions	P49757, Q6NUQ7, Q86SY1, Q8WW73, Q9UBG1, Q9UEQ4, Q9UKE8, Q9UKE9, Q9UKF0, Q9UQJ4	Gene names	NUMB
Domain Architecture
Description	Protein numb homolog (h-Numb) (Protein S171).

FA98A_HUMAN
NC score	0.024081 (rank : 20)	θ value	3.0926 (rank : 17)
Query Neighborhood Hits	34	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NCA5	Gene names	FAM98A
Domain Architecture	No domain graphic available
Description	Protein FAM98A.

FBW1B_HUMAN
NC score	0.023465 (rank : 21)	θ value	1.06291 (rank : 12)
Query Neighborhood Hits	34	Target Neighborhood Hits	327	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKB1, Q9P2S8, Q9P2S9, Q9Y4C6	Gene names	FBXW11, BTRCP2, FBW1B, FBXW1B, KIAA0696
Domain Architecture
Description	F-box/WD repeat protein 11 (F-box/WD repeat protein 1B) (F-box and WD repeats protein beta-TrCP2).

FBW1A_HUMAN
NC score	0.023092 (rank : 22)	θ value	1.38821 (rank : 13)
Query Neighborhood Hits	34	Target Neighborhood Hits	329	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y297, Q9Y213	Gene names	BTRC, BTRCP, FBW1A, FBXW1A
Domain Architecture
Description	F-box/WD repeat protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit).

BRAP_MOUSE
NC score	0.019940 (rank : 23)	θ value	3.0926 (rank : 14)
Query Neighborhood Hits	34	Target Neighborhood Hits	409	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

CA049_MOUSE
NC score	0.017635 (rank : 24)	θ value	8.99809 (rank : 30)
Query Neighborhood Hits	34	Target Neighborhood Hits	121	Shared Neighborhood Hits	2
SwissProt Accessions	Q14BK3, Q4KKY9, Q9D9J9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf49 homolog.

K0406_HUMAN
NC score	0.017353 (rank : 25)	θ value	6.88961 (rank : 27)
Query Neighborhood Hits	34	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	O43156, Q5JX67, Q96A38, Q9BR47, Q9H4K0	Gene names	KIAA0406
Domain Architecture	No domain graphic available
Description	Protein KIAA0406.

DGKK_HUMAN
NC score	0.016398 (rank : 26)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	34	Target Neighborhood Hits	378	Shared Neighborhood Hits	3
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

SH24A_HUMAN
NC score	0.014730 (rank : 27)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	34	Target Neighborhood Hits	455	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7	Gene names	SH2D4A, SH2A
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A (Protein SH(2)A).

CCD91_MOUSE
NC score	0.013968 (rank : 28)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	34	Target Neighborhood Hits	699	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

H15_MOUSE
NC score	0.012803 (rank : 29)	θ value	6.88961 (rank : 26)
Query Neighborhood Hits	34	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	P43276, Q9CRM8	Gene names	Hist1h1b, H1f5
Domain Architecture
Description	Histone H1.5 (H1 VAR.5) (H1b).

OXR1_MOUSE
NC score	0.010350 (rank : 30)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	34	Target Neighborhood Hits	516	Shared Neighborhood Hits	5
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

AL3B1_HUMAN
NC score	0.010348 (rank : 31)	θ value	5.27518 (rank : 20)
Query Neighborhood Hits	34	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	P43353, Q53XL5, Q8N515, Q96CK8	Gene names	ALDH3B1, ALDH7
Domain Architecture
Description	Aldehyde dehydrogenase 3B1 (EC 1.2.1.5) (Aldehyde dehydrogenase 7).

SMAL1_HUMAN
NC score	0.008773 (rank : 32)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	34	Target Neighborhood Hits	174	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

JHD2A_MOUSE
NC score	0.008462 (rank : 33)	θ value	8.99809 (rank : 31)
Query Neighborhood Hits	34	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PCM1, Q2MJQ6, Q3TKW8, Q3UML3, Q6ZQ57, Q8K2J6, Q8K2K4, Q8R350	Gene names	Jmjd1a, Jhdm2a, Kiaa0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

ANXA7_MOUSE
NC score	0.008435 (rank : 34)	θ value	8.99809 (rank : 29)
Query Neighborhood Hits	34	Target Neighborhood Hits	142	Shared Neighborhood Hits	4
SwissProt Accessions	Q07076	Gene names	Anxa7, Anx7
Domain Architecture
Description	Annexin A7 (Annexin VII) (Synexin).

ANXA7_HUMAN
NC score	0.008224 (rank : 35)	θ value	8.99809 (rank : 28)
Query Neighborhood Hits	34	Target Neighborhood Hits	168	Shared Neighborhood Hits	3
SwissProt Accessions	P20073	Gene names	ANXA7, ANX7, SNX
Domain Architecture
Description	Annexin A7 (Annexin VII) (Synexin).

PCLO_MOUSE
NC score	0.007904 (rank : 36)	θ value	5.27518 (rank : 21)
Query Neighborhood Hits	34	Target Neighborhood Hits	2275	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

WEE1_HUMAN
NC score	0.006923 (rank : 37)	θ value	4.03905 (rank : 19)
Query Neighborhood Hits	34	Target Neighborhood Hits	777	Shared Neighborhood Hits	3
SwissProt Accessions	P30291	Gene names	WEE1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase) (WEE1hu).

AT11B_HUMAN
NC score	0.006508 (rank : 38)	θ value	6.88961 (rank : 25)
Query Neighborhood Hits	34	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2G3, Q96FN1, Q9UKK7	Gene names	ATP11B, ATPIF, ATPIR, KIAA0956
Domain Architecture
Description	Probable phospholipid-transporting ATPase IF (EC 3.6.3.1) (ATPase class I type 11B) (ATPase IR).

WEE1_MOUSE
NC score	0.005026 (rank : 39)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	34	Target Neighborhood Hits	794	Shared Neighborhood Hits	3
SwissProt Accessions	P47810, Q9EPL7	Gene names	Wee1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase).

RUFY2_HUMAN
NC score	0.004716 (rank : 40)	θ value	5.27518 (rank : 23)
Query Neighborhood Hits	34	Target Neighborhood Hits	1208	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).