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Network neighborhood for query Sequence : IBRD2_MOUSE

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IBRD2_MOUSE
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IBRD2_MOUSE
θ value	2.56852e-180 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).

IBRD2_HUMAN
θ value	7.25522e-167 (rank : 2)	NC score	0.993731 (rank : 2)
Query Neighborhood Hits	46	Target Neighborhood Hits	55	Shared Neighborhood Hits	40
SwissProt Accessions	Q7Z419, Q6P4Q0, Q8N3R7, Q9BX38	Gene names	IBRDC2, P53RFP
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2) (p53-inducible RING finger protein).

UB7I4_MOUSE
θ value	2.30828e-88 (rank : 3)	NC score	0.971135 (rank : 4)
Query Neighborhood Hits	46	Target Neighborhood Hits	59	Shared Neighborhood Hits	25
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

UB7I4_HUMAN
θ value	5.14231e-88 (rank : 4)	NC score	0.971221 (rank : 3)
Query Neighborhood Hits	46	Target Neighborhood Hits	54	Shared Neighborhood Hits	25
SwissProt Accessions	P50876	Gene names	RNF144, KIAA0161, UBCE7IP4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

RNF14_MOUSE
θ value	2.43343e-21 (rank : 5)	NC score	0.786965 (rank : 5)
Query Neighborhood Hits	46	Target Neighborhood Hits	69	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JI90, Q9D0L2, Q9D6N2, Q9D6Z8, Q9JI89	Gene names	Rnf14, Ara54, Triad2
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein).

RNF14_HUMAN
θ value	2.06002e-20 (rank : 6)	NC score	0.779695 (rank : 6)
Query Neighborhood Hits	46	Target Neighborhood Hits	70	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UBS8, O94793, Q6IBV0	Gene names	RNF14, ARA54
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein) (HFB30).

ARI2_HUMAN
θ value	8.65492e-19 (rank : 7)	NC score	0.760407 (rank : 9)
Query Neighborhood Hits	46	Target Neighborhood Hits	113	Shared Neighborhood Hits	24
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

ARI2_MOUSE
θ value	1.92812e-18 (rank : 8)	NC score	0.758203 (rank : 10)
Query Neighborhood Hits	46	Target Neighborhood Hits	106	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

ARI1_HUMAN
θ value	3.28887e-18 (rank : 9)	NC score	0.761506 (rank : 7)
Query Neighborhood Hits	46	Target Neighborhood Hits	71	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y4X5, O76026, Q9H3T6, Q9UEN0, Q9UP39	Gene names	ARIH1, ARI, UBCH7BP
Domain Architecture
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6).

ARI1_MOUSE
θ value	3.28887e-18 (rank : 10)	NC score	0.761359 (rank : 8)
Query Neighborhood Hits	46	Target Neighborhood Hits	71	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z1K5, Q6PF92	Gene names	Arih1, Ari, Ubch7bp, Uip77
Domain Architecture	No domain graphic available
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein 77).

IBRD3_HUMAN
θ value	9.56915e-18 (rank : 11)	NC score	0.755273 (rank : 11)
Query Neighborhood Hits	46	Target Neighborhood Hits	70	Shared Neighborhood Hits	28
SwissProt Accessions	Q6ZMZ0, Q6P6A4	Gene names	IBRDC3
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 3.

RNF19_HUMAN
θ value	1.38178e-16 (rank : 12)	NC score	0.716493 (rank : 14)
Query Neighborhood Hits	46	Target Neighborhood Hits	105	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

RNF19_MOUSE
θ value	1.38178e-16 (rank : 13)	NC score	0.718963 (rank : 13)
Query Neighborhood Hits	46	Target Neighborhood Hits	96	Shared Neighborhood Hits	30
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

RNF31_MOUSE
θ value	7.58209e-15 (rank : 14)	NC score	0.614675 (rank : 18)
Query Neighborhood Hits	46	Target Neighborhood Hits	113	Shared Neighborhood Hits	29
SwissProt Accessions	Q924T7	Gene names	Rnf31
Domain Architecture
Description	RING finger protein 31.

RNF31_HUMAN
θ value	9.90251e-15 (rank : 15)	NC score	0.616931 (rank : 17)
Query Neighborhood Hits	46	Target Neighborhood Hits	110	Shared Neighborhood Hits	28
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

UB7I3_MOUSE
θ value	6.00763e-12 (rank : 16)	NC score	0.625781 (rank : 16)
Query Neighborhood Hits	46	Target Neighborhood Hits	131	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

PARC_HUMAN
θ value	1.33837e-11 (rank : 17)	NC score	0.551799 (rank : 19)
Query Neighborhood Hits	46	Target Neighborhood Hits	148	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

PARC_MOUSE
θ value	2.28291e-11 (rank : 18)	NC score	0.542338 (rank : 20)
Query Neighborhood Hits	46	Target Neighborhood Hits	114	Shared Neighborhood Hits	25
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

UB7I3_HUMAN
θ value	2.98157e-11 (rank : 19)	NC score	0.626763 (rank : 15)
Query Neighborhood Hits	46	Target Neighborhood Hits	136	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

IBRD1_HUMAN
θ value	6.64225e-11 (rank : 20)	NC score	0.736921 (rank : 12)
Query Neighborhood Hits	46	Target Neighborhood Hits	62	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TC41, Q9BX48	Gene names	IBRDC1
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 1.

UB7I1_MOUSE
θ value	2.88788e-06 (rank : 21)	NC score	0.530240 (rank : 21)
Query Neighborhood Hits	46	Target Neighborhood Hits	206	Shared Neighborhood Hits	24
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

UB7I1_HUMAN
θ value	1.43324e-05 (rank : 22)	NC score	0.527247 (rank : 22)
Query Neighborhood Hits	46	Target Neighborhood Hits	177	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

PRKN2_HUMAN
θ value	9.29e-05 (rank : 23)	NC score	0.523174 (rank : 24)
Query Neighborhood Hits	46	Target Neighborhood Hits	65	Shared Neighborhood Hits	24
SwissProt Accessions	O60260, Q5TFV8, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07	Gene names	PARK2, PRKN
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2).

PRKN2_MOUSE
θ value	0.000121331 (rank : 24)	NC score	0.525200 (rank : 23)
Query Neighborhood Hits	46	Target Neighborhood Hits	69	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WVS6, Q9ES22, Q9ES23	Gene names	Park2, Prkn
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN).

TRIM2_MOUSE
θ value	0.0563607 (rank : 25)	NC score	0.061993 (rank : 29)
Query Neighborhood Hits	46	Target Neighborhood Hits	331	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRIM2_HUMAN
θ value	0.0736092 (rank : 26)	NC score	0.062881 (rank : 28)
Query Neighborhood Hits	46	Target Neighborhood Hits	330	Shared Neighborhood Hits	23
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

CM007_MOUSE
θ value	0.125558 (rank : 27)	NC score	0.054034 (rank : 35)
Query Neighborhood Hits	46	Target Neighborhood Hits	416	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

CM007_HUMAN
θ value	0.163984 (rank : 28)	NC score	0.051616 (rank : 38)
Query Neighborhood Hits	46	Target Neighborhood Hits	422	Shared Neighborhood Hits	11
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

TRIM1_HUMAN
θ value	0.163984 (rank : 29)	NC score	0.043818 (rank : 42)
Query Neighborhood Hits	46	Target Neighborhood Hits	345	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
θ value	0.163984 (rank : 30)	NC score	0.039924 (rank : 44)
Query Neighborhood Hits	46	Target Neighborhood Hits	361	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

ZAN_MOUSE
θ value	0.279714 (rank : 31)	NC score	0.023090 (rank : 46)
Query Neighborhood Hits	46	Target Neighborhood Hits	808	Shared Neighborhood Hits	10
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

FRAS1_MOUSE
θ value	0.365318 (rank : 32)	NC score	0.023127 (rank : 45)
Query Neighborhood Hits	46	Target Neighborhood Hits	747	Shared Neighborhood Hits	11
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

KRA24_HUMAN
θ value	0.813845 (rank : 33)	NC score	0.020164 (rank : 48)
Query Neighborhood Hits	46	Target Neighborhood Hits	192	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

ORC6_MOUSE
θ value	0.813845 (rank : 34)	NC score	0.053209 (rank : 37)
Query Neighborhood Hits	46	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WUJ8	Gene names	Orc6l, Orc6
Domain Architecture
Description	Origin recognition complex subunit 6.

SUHW3_MOUSE
θ value	0.813845 (rank : 35)	NC score	0.008470 (rank : 51)
Query Neighborhood Hits	46	Target Neighborhood Hits	697	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P3Y5, Q6ZPM2, Q8K145	Gene names	Suhw3, Kiaa1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 3.

CRDL2_HUMAN
θ value	2.36792 (rank : 36)	NC score	0.022002 (rank : 47)
Query Neighborhood Hits	46	Target Neighborhood Hits	99	Shared Neighborhood Hits	6
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

CHFR_HUMAN
θ value	3.0926 (rank : 37)	NC score	0.066586 (rank : 26)
Query Neighborhood Hits	46	Target Neighborhood Hits	255	Shared Neighborhood Hits	20
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
θ value	3.0926 (rank : 38)	NC score	0.059566 (rank : 32)
Query Neighborhood Hits	46	Target Neighborhood Hits	264	Shared Neighborhood Hits	20
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

PAXI_HUMAN
θ value	4.03905 (rank : 39)	NC score	0.009712 (rank : 50)
Query Neighborhood Hits	46	Target Neighborhood Hits	173	Shared Neighborhood Hits	4
SwissProt Accessions	P49023, O14970, O14971, O60360	Gene names	PXN
Domain Architecture
Description	Paxillin.

POGZ_MOUSE
θ value	4.03905 (rank : 40)	NC score	0.004346 (rank : 52)
Query Neighborhood Hits	46	Target Neighborhood Hits	765	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BZH4, Q4VA94, Q80TZ8, Q8C0K1, Q8K294	Gene names	Pogz, Kiaa0461
Domain Architecture
Description	Pogo transposable element with ZNF domain.

TRIM3_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.065162 (rank : 27)
Query Neighborhood Hits	46	Target Neighborhood Hits	357	Shared Neighborhood Hits	22
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRI42_MOUSE
θ value	5.27518 (rank : 42)	NC score	0.041995 (rank : 43)
Query Neighborhood Hits	46	Target Neighborhood Hits	316	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

KR101_HUMAN
θ value	6.88961 (rank : 43)	NC score	0.019885 (rank : 49)
Query Neighborhood Hits	46	Target Neighborhood Hits	261	Shared Neighborhood Hits	8
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

RNF4_HUMAN
θ value	6.88961 (rank : 44)	NC score	0.049463 (rank : 40)
Query Neighborhood Hits	46	Target Neighborhood Hits	212	Shared Neighborhood Hits	16
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	6.88961 (rank : 45)	NC score	0.046078 (rank : 41)
Query Neighborhood Hits	46	Target Neighborhood Hits	212	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

TRIM3_MOUSE
θ value	6.88961 (rank : 46)	NC score	0.059137 (rank : 33)
Query Neighborhood Hits	46	Target Neighborhood Hits	351	Shared Neighborhood Hits	23
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

CUL7_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.119955 (rank : 25)
Query Neighborhood Hits	46	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

FBX43_HUMAN
θ value	θ > 10 (rank : 48)	NC score	0.051159 (rank : 39)
Query Neighborhood Hits	46	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	Q4G163	Gene names	FBXO43, EMI2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

FBX43_MOUSE
θ value	θ > 10 (rank : 49)	NC score	0.053978 (rank : 36)
Query Neighborhood Hits	46	Target Neighborhood Hits	40	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CDI2, Q4G0C8, Q8R0R1	Gene names	Fbxo43, Emi2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

RN152_HUMAN
θ value	θ > 10 (rank : 50)	NC score	0.060400 (rank : 30)
Query Neighborhood Hits	46	Target Neighborhood Hits	107	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RN152_MOUSE
θ value	θ > 10 (rank : 51)	NC score	0.060288 (rank : 31)
Query Neighborhood Hits	46	Target Neighborhood Hits	109	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

TRI56_MOUSE
θ value	θ > 10 (rank : 52)	NC score	0.055499 (rank : 34)
Query Neighborhood Hits	46	Target Neighborhood Hits	255	Shared Neighborhood Hits	18
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

Hits sorted by NC score

IBRD2_MOUSE
NC score	0.999962 (rank : 1)	θ value	2.56852e-180 (rank : 1)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).

IBRD2_HUMAN
NC score	0.993731 (rank : 2)	θ value	7.25522e-167 (rank : 2)
Query Neighborhood Hits	46	Target Neighborhood Hits	55	Shared Neighborhood Hits	40
SwissProt Accessions	Q7Z419, Q6P4Q0, Q8N3R7, Q9BX38	Gene names	IBRDC2, P53RFP
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2) (p53-inducible RING finger protein).

UB7I4_HUMAN
NC score	0.971221 (rank : 3)	θ value	5.14231e-88 (rank : 4)
Query Neighborhood Hits	46	Target Neighborhood Hits	54	Shared Neighborhood Hits	25
SwissProt Accessions	P50876	Gene names	RNF144, KIAA0161, UBCE7IP4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

UB7I4_MOUSE
NC score	0.971135 (rank : 4)	θ value	2.30828e-88 (rank : 3)
Query Neighborhood Hits	46	Target Neighborhood Hits	59	Shared Neighborhood Hits	25
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

RNF14_MOUSE
NC score	0.786965 (rank : 5)	θ value	2.43343e-21 (rank : 5)
Query Neighborhood Hits	46	Target Neighborhood Hits	69	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JI90, Q9D0L2, Q9D6N2, Q9D6Z8, Q9JI89	Gene names	Rnf14, Ara54, Triad2
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein).

RNF14_HUMAN
NC score	0.779695 (rank : 6)	θ value	2.06002e-20 (rank : 6)
Query Neighborhood Hits	46	Target Neighborhood Hits	70	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UBS8, O94793, Q6IBV0	Gene names	RNF14, ARA54
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein) (HFB30).

ARI1_HUMAN
NC score	0.761506 (rank : 7)	θ value	3.28887e-18 (rank : 9)
Query Neighborhood Hits	46	Target Neighborhood Hits	71	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y4X5, O76026, Q9H3T6, Q9UEN0, Q9UP39	Gene names	ARIH1, ARI, UBCH7BP
Domain Architecture
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6).

ARI1_MOUSE
NC score	0.761359 (rank : 8)	θ value	3.28887e-18 (rank : 10)
Query Neighborhood Hits	46	Target Neighborhood Hits	71	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z1K5, Q6PF92	Gene names	Arih1, Ari, Ubch7bp, Uip77
Domain Architecture	No domain graphic available
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein 77).

ARI2_HUMAN
NC score	0.760407 (rank : 9)	θ value	8.65492e-19 (rank : 7)
Query Neighborhood Hits	46	Target Neighborhood Hits	113	Shared Neighborhood Hits	24
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

ARI2_MOUSE
NC score	0.758203 (rank : 10)	θ value	1.92812e-18 (rank : 8)
Query Neighborhood Hits	46	Target Neighborhood Hits	106	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

IBRD3_HUMAN
NC score	0.755273 (rank : 11)	θ value	9.56915e-18 (rank : 11)
Query Neighborhood Hits	46	Target Neighborhood Hits	70	Shared Neighborhood Hits	28
SwissProt Accessions	Q6ZMZ0, Q6P6A4	Gene names	IBRDC3
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 3.

IBRD1_HUMAN
NC score	0.736921 (rank : 12)	θ value	6.64225e-11 (rank : 20)
Query Neighborhood Hits	46	Target Neighborhood Hits	62	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TC41, Q9BX48	Gene names	IBRDC1
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 1.

RNF19_MOUSE
NC score	0.718963 (rank : 13)	θ value	1.38178e-16 (rank : 13)
Query Neighborhood Hits	46	Target Neighborhood Hits	96	Shared Neighborhood Hits	30
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

RNF19_HUMAN
NC score	0.716493 (rank : 14)	θ value	1.38178e-16 (rank : 12)
Query Neighborhood Hits	46	Target Neighborhood Hits	105	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

UB7I3_HUMAN
NC score	0.626763 (rank : 15)	θ value	2.98157e-11 (rank : 19)
Query Neighborhood Hits	46	Target Neighborhood Hits	136	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

UB7I3_MOUSE
NC score	0.625781 (rank : 16)	θ value	6.00763e-12 (rank : 16)
Query Neighborhood Hits	46	Target Neighborhood Hits	131	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

RNF31_HUMAN
NC score	0.616931 (rank : 17)	θ value	9.90251e-15 (rank : 15)
Query Neighborhood Hits	46	Target Neighborhood Hits	110	Shared Neighborhood Hits	28
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

RNF31_MOUSE
NC score	0.614675 (rank : 18)	θ value	7.58209e-15 (rank : 14)
Query Neighborhood Hits	46	Target Neighborhood Hits	113	Shared Neighborhood Hits	29
SwissProt Accessions	Q924T7	Gene names	Rnf31
Domain Architecture
Description	RING finger protein 31.

PARC_HUMAN
NC score	0.551799 (rank : 19)	θ value	1.33837e-11 (rank : 17)
Query Neighborhood Hits	46	Target Neighborhood Hits	148	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

PARC_MOUSE
NC score	0.542338 (rank : 20)	θ value	2.28291e-11 (rank : 18)
Query Neighborhood Hits	46	Target Neighborhood Hits	114	Shared Neighborhood Hits	25
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

UB7I1_MOUSE
NC score	0.530240 (rank : 21)	θ value	2.88788e-06 (rank : 21)
Query Neighborhood Hits	46	Target Neighborhood Hits	206	Shared Neighborhood Hits	24
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

UB7I1_HUMAN
NC score	0.527247 (rank : 22)	θ value	1.43324e-05 (rank : 22)
Query Neighborhood Hits	46	Target Neighborhood Hits	177	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

PRKN2_MOUSE
NC score	0.525200 (rank : 23)	θ value	0.000121331 (rank : 24)
Query Neighborhood Hits	46	Target Neighborhood Hits	69	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WVS6, Q9ES22, Q9ES23	Gene names	Park2, Prkn
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN).

PRKN2_HUMAN
NC score	0.523174 (rank : 24)	θ value	9.29e-05 (rank : 23)
Query Neighborhood Hits	46	Target Neighborhood Hits	65	Shared Neighborhood Hits	24
SwissProt Accessions	O60260, Q5TFV8, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07	Gene names	PARK2, PRKN
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2).

CUL7_HUMAN
NC score	0.119955 (rank : 25)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	46	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

CHFR_HUMAN
NC score	0.066586 (rank : 26)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	46	Target Neighborhood Hits	255	Shared Neighborhood Hits	20
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

TRIM3_HUMAN
NC score	0.065162 (rank : 27)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	46	Target Neighborhood Hits	357	Shared Neighborhood Hits	22
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM2_HUMAN
NC score	0.062881 (rank : 28)	θ value	0.0736092 (rank : 26)
Query Neighborhood Hits	46	Target Neighborhood Hits	330	Shared Neighborhood Hits	23
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
NC score	0.061993 (rank : 29)	θ value	0.0563607 (rank : 25)
Query Neighborhood Hits	46	Target Neighborhood Hits	331	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

RN152_HUMAN
NC score	0.060400 (rank : 30)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	46	Target Neighborhood Hits	107	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RN152_MOUSE
NC score	0.060288 (rank : 31)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	46	Target Neighborhood Hits	109	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

CHFR_MOUSE
NC score	0.059566 (rank : 32)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	46	Target Neighborhood Hits	264	Shared Neighborhood Hits	20
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

TRIM3_MOUSE
NC score	0.059137 (rank : 33)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	46	Target Neighborhood Hits	351	Shared Neighborhood Hits	23
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRI56_MOUSE
NC score	0.055499 (rank : 34)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	46	Target Neighborhood Hits	255	Shared Neighborhood Hits	18
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

CM007_MOUSE
NC score	0.054034 (rank : 35)	θ value	0.125558 (rank : 27)
Query Neighborhood Hits	46	Target Neighborhood Hits	416	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

FBX43_MOUSE
NC score	0.053978 (rank : 36)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	46	Target Neighborhood Hits	40	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CDI2, Q4G0C8, Q8R0R1	Gene names	Fbxo43, Emi2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

ORC6_MOUSE
NC score	0.053209 (rank : 37)	θ value	0.813845 (rank : 34)
Query Neighborhood Hits	46	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WUJ8	Gene names	Orc6l, Orc6
Domain Architecture
Description	Origin recognition complex subunit 6.

CM007_HUMAN
NC score	0.051616 (rank : 38)	θ value	0.163984 (rank : 28)
Query Neighborhood Hits	46	Target Neighborhood Hits	422	Shared Neighborhood Hits	11
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

FBX43_HUMAN
NC score	0.051159 (rank : 39)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	46	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	Q4G163	Gene names	FBXO43, EMI2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

RNF4_HUMAN
NC score	0.049463 (rank : 40)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	46	Target Neighborhood Hits	212	Shared Neighborhood Hits	16
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
NC score	0.046078 (rank : 41)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	46	Target Neighborhood Hits	212	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

TRIM1_HUMAN
NC score	0.043818 (rank : 42)	θ value	0.163984 (rank : 29)
Query Neighborhood Hits	46	Target Neighborhood Hits	345	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRI42_MOUSE
NC score	0.041995 (rank : 43)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	46	Target Neighborhood Hits	316	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRIM1_MOUSE
NC score	0.039924 (rank : 44)	θ value	0.163984 (rank : 30)
Query Neighborhood Hits	46	Target Neighborhood Hits	361	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

FRAS1_MOUSE
NC score	0.023127 (rank : 45)	θ value	0.365318 (rank : 32)
Query Neighborhood Hits	46	Target Neighborhood Hits	747	Shared Neighborhood Hits	11
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

ZAN_MOUSE
NC score	0.023090 (rank : 46)	θ value	0.279714 (rank : 31)
Query Neighborhood Hits	46	Target Neighborhood Hits	808	Shared Neighborhood Hits	10
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

CRDL2_HUMAN
NC score	0.022002 (rank : 47)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	46	Target Neighborhood Hits	99	Shared Neighborhood Hits	6
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

KRA24_HUMAN
NC score	0.020164 (rank : 48)	θ value	0.813845 (rank : 33)
Query Neighborhood Hits	46	Target Neighborhood Hits	192	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

KR101_HUMAN
NC score	0.019885 (rank : 49)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	46	Target Neighborhood Hits	261	Shared Neighborhood Hits	8
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

PAXI_HUMAN
NC score	0.009712 (rank : 50)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	46	Target Neighborhood Hits	173	Shared Neighborhood Hits	4
SwissProt Accessions	P49023, O14970, O14971, O60360	Gene names	PXN
Domain Architecture
Description	Paxillin.

SUHW3_MOUSE
NC score	0.008470 (rank : 51)	θ value	0.813845 (rank : 35)
Query Neighborhood Hits	46	Target Neighborhood Hits	697	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P3Y5, Q6ZPM2, Q8K145	Gene names	Suhw3, Kiaa1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 3.

POGZ_MOUSE
NC score	0.004346 (rank : 52)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	46	Target Neighborhood Hits	765	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BZH4, Q4VA94, Q80TZ8, Q8C0K1, Q8K294	Gene names	Pogz, Kiaa0461
Domain Architecture
Description	Pogo transposable element with ZNF domain.