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Network neighborhood for query Sequence : PRKN2_HUMAN

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PRKN2_HUMAN
SwissProt Accessions	O60260, Q5TFV8, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07	Gene names	PARK2, PRKN
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PRKN2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	O60260, Q5TFV8, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07	Gene names	PARK2, PRKN
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2).

PRKN2_MOUSE
θ value	0 (rank : 2)	NC score	0.993965 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	69	Shared Neighborhood Hits	53
SwissProt Accessions	Q9WVS6, Q9ES22, Q9ES23	Gene names	Park2, Prkn
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN).

ARI1_HUMAN
θ value	1.16975e-15 (rank : 3)	NC score	0.668064 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	71	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y4X5, O76026, Q9H3T6, Q9UEN0, Q9UP39	Gene names	ARIH1, ARI, UBCH7BP
Domain Architecture
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6).

ARI1_MOUSE
θ value	1.16975e-15 (rank : 4)	NC score	0.667934 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	71	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z1K5, Q6PF92	Gene names	Arih1, Ari, Ubch7bp, Uip77
Domain Architecture	No domain graphic available
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein 77).

ARI2_MOUSE
θ value	2.20605e-14 (rank : 5)	NC score	0.654115 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	106	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

ARI2_HUMAN
θ value	3.76295e-14 (rank : 6)	NC score	0.653413 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	113	Shared Neighborhood Hits	26
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

RNF14_HUMAN
θ value	6.41864e-14 (rank : 7)	NC score	0.646656 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	70	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UBS8, O94793, Q6IBV0	Gene names	RNF14, ARA54
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein) (HFB30).

RNF14_MOUSE
θ value	9.26847e-13 (rank : 8)	NC score	0.639218 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	69	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JI90, Q9D0L2, Q9D6N2, Q9D6Z8, Q9JI89	Gene names	Rnf14, Ara54, Triad2
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein).

PARC_HUMAN
θ value	5.08577e-11 (rank : 9)	NC score	0.499873 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	148	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

PARC_MOUSE
θ value	1.9326e-10 (rank : 10)	NC score	0.492443 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	114	Shared Neighborhood Hits	24
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

IBRD3_HUMAN
θ value	8.97725e-08 (rank : 11)	NC score	0.556366 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	70	Shared Neighborhood Hits	27
SwissProt Accessions	Q6ZMZ0, Q6P6A4	Gene names	IBRDC3
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 3.

RNF19_HUMAN
θ value	1.99992e-07 (rank : 12)	NC score	0.527296 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	105	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

RNF19_MOUSE
θ value	1.99992e-07 (rank : 13)	NC score	0.528703 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	96	Shared Neighborhood Hits	28
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

UB7I4_HUMAN
θ value	9.92553e-07 (rank : 14)	NC score	0.553920 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	54	Shared Neighborhood Hits	24
SwissProt Accessions	P50876	Gene names	RNF144, KIAA0161, UBCE7IP4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

IBRD1_HUMAN
θ value	2.21117e-06 (rank : 15)	NC score	0.572802 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	62	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TC41, Q9BX48	Gene names	IBRDC1
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 1.

UB7I4_MOUSE
θ value	4.92598e-06 (rank : 16)	NC score	0.549502 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	59	Shared Neighborhood Hits	24
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

UBIQ_HUMAN
θ value	4.92598e-06 (rank : 17)	NC score	0.331745 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	49	Shared Neighborhood Hits	27
SwissProt Accessions	P62988, P02248, P02249, P02250, Q29120, Q6LBL4, Q6LDU5, Q91887, Q91888, Q9BWD6, Q9BX98, Q9UEF2, Q9UEG1, Q9UEK8, Q9UPK7	Gene names	RPS27A, UBA80, UBCEP1
Domain Architecture	No domain graphic available
Description	Ubiquitin.

UBIQ_MOUSE
θ value	4.92598e-06 (rank : 18)	NC score	0.331745 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	49	Shared Neighborhood Hits	27
SwissProt Accessions	P62991, P02248, P02249, P02250, Q29120, Q62317, Q64223, Q8VCH1, Q91887, Q91888, Q9CXY4, Q9CZM0, Q9D1R5, Q9D8D9, Q9ET23, Q9ET24, Q9Z0H9	Gene names	Rps27a, Uba80, Ubcep1
Domain Architecture	No domain graphic available
Description	Ubiquitin.

UB7I3_HUMAN
θ value	3.19293e-05 (rank : 19)	NC score	0.450344 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	136	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

IBRD2_MOUSE
θ value	9.29e-05 (rank : 20)	NC score	0.523174 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	46	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).

UB7I3_MOUSE
θ value	9.29e-05 (rank : 21)	NC score	0.445395 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	131	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

IBRD2_HUMAN
θ value	0.000602161 (rank : 22)	NC score	0.515899 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	55	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z419, Q6P4Q0, Q8N3R7, Q9BX38	Gene names	IBRDC2, P53RFP
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2) (p53-inducible RING finger protein).

NEDD8_HUMAN
θ value	0.00298849 (rank : 23)	NC score	0.283032 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	40	Shared Neighborhood Hits	25
SwissProt Accessions	Q15843, Q6LES6	Gene names	NEDD8
Domain Architecture
Description	NEDD8 precursor (Ubiquitin-like protein Nedd8) (Neddylin).

NEDD8_MOUSE
θ value	0.00298849 (rank : 24)	NC score	0.282851 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	40	Shared Neighborhood Hits	25
SwissProt Accessions	P29595	Gene names	Nedd8, Nedd-8
Domain Architecture
Description	NEDD8 precursor (Ubiquitin-like protein Nedd8) (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8).

RNF31_MOUSE
θ value	0.00298849 (rank : 25)	NC score	0.387873 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	113	Shared Neighborhood Hits	32
SwissProt Accessions	Q924T7	Gene names	Rnf31
Domain Architecture
Description	RING finger protein 31.

UB7I1_HUMAN
θ value	0.00298849 (rank : 26)	NC score	0.378546 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	177	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

RNF31_HUMAN
θ value	0.00390308 (rank : 27)	NC score	0.387565 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	110	Shared Neighborhood Hits	31
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

UBQL2_HUMAN
θ value	0.00665767 (rank : 28)	NC score	0.189989 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	103	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UHD9, O94798, Q9H3W6, Q9HAZ4	Gene names	UBQLN2, PLIC2
Domain Architecture
Description	Ubiquilin-2 (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC- 2) (Ubiquitin-like product Chap1/Dsk2) (DSK2 homolog) (Chap1).

SUMO1_HUMAN
θ value	0.00869519 (rank : 29)	NC score	0.172556 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P63165, P55856, Q6FGG0, Q6NZ62, Q93068	Gene names	SUMO1, SMT3C, SMT3H3, UBL1
Domain Architecture	No domain graphic available
Description	Small ubiquitin-related modifier 1 precursor (SUMO-1) (Ubiquitin-like protein SMT3C) (SMT3 homolog 3) (Ubiquitin-homology domain protein PIC1) (Ubiquitin-like protein UBL1) (GAP-modifying protein 1) (GMP1) (Sentrin).

SUMO1_MOUSE
θ value	0.00869519 (rank : 30)	NC score	0.172556 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P63166, P55856, Q3TX92, Q93068	Gene names	Sumo1, Smt3c, Smt3h3, Ubl1
Domain Architecture	No domain graphic available
Description	Small ubiquitin-related modifier 1 precursor (SUMO-1) (Ubiquitin-like protein SMT3C) (SMT3 homolog 3) (Ubiquitin-homology domain protein PIC1).

UB7I1_MOUSE
θ value	0.00869519 (rank : 31)	NC score	0.372632 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	206	Shared Neighborhood Hits	26
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

UBQL1_HUMAN
θ value	0.0252991 (rank : 32)	NC score	0.193107 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	72	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UMX0, Q8IXS9, Q8N2Q3, Q9H0T8, Q9H3R4, Q9HAZ5	Gene names	UBQLN1, DA41, PLIC1
Domain Architecture
Description	Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC- 1).

UBQL1_MOUSE
θ value	0.0252991 (rank : 33)	NC score	0.191614 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	86	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R317, Q80V10, Q8C7T4, Q8C835, Q8K141, Q91VI8, Q9D0Z0, Q9QZM1	Gene names	Ubqln1, Plic1
Domain Architecture
Description	Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1).

UBQL3_HUMAN
θ value	0.0252991 (rank : 34)	NC score	0.193494 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	141	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H347, Q9NRE0	Gene names	UBQLN3
Domain Architecture
Description	Ubiquilin-3.

UBQL2_MOUSE
θ value	0.0431538 (rank : 35)	NC score	0.181914 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	114	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QZM0, Q7TSJ8, Q8VDH9	Gene names	Ubqln2, Plic2
Domain Architecture
Description	Ubiquilin-2 (Protein linking IAP with cytoskeleton 2) (PLIC-2) (Ubiquitin-like product Chap1/Dsk2) (DSK2 homolog) (Chap1).

UBQL4_MOUSE
θ value	0.0431538 (rank : 36)	NC score	0.182590 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	99	Shared Neighborhood Hits	23
SwissProt Accessions	Q99NB8, Q8BP88	Gene names	Ubqln4, Ubin
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

UBQL4_HUMAN
θ value	0.0736092 (rank : 37)	NC score	0.185949 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	117	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NRR5, Q9BR98, Q9UHX4	Gene names	UBQLN4, C1orf6, UBIN
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

MLL2_HUMAN
θ value	0.0961366 (rank : 38)	NC score	0.045092 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	1788	Shared Neighborhood Hits	15
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

UBL4A_HUMAN
θ value	0.163984 (rank : 39)	NC score	0.198194 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	P11441	Gene names	UBL4A, DXS254E, GDX, UBL4
Domain Architecture
Description	Ubiquitin-like protein 4A (Ubiquitin-like protein GDX).

UBIM_HUMAN
θ value	0.21417 (rank : 40)	NC score	0.188748 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	19	Shared Neighborhood Hits	11
SwissProt Accessions	P35544, Q9H5V4	Gene names	FAU
Domain Architecture
Description	Ubiquitin-like protein FUBI.

UBIM_MOUSE
θ value	0.21417 (rank : 41)	NC score	0.191230 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	P35545, Q9JJ24	Gene names	Fau
Domain Architecture
Description	Ubiquitin-like protein FUBI (Monoclonal nonspecific suppressor factor beta) (MNSF-beta).

UBL4A_MOUSE
θ value	0.21417 (rank : 42)	NC score	0.186058 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	38	Shared Neighborhood Hits	22
SwissProt Accessions	P21126	Gene names	Ubl4a, Gdx, Ubl4
Domain Architecture
Description	Ubiquitin-like protein 4A (Ubiquitin-like protein GDX).

RPC11_MOUSE
θ value	0.47712 (rank : 43)	NC score	0.101275 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CQZ7, Q9D1U1	Gene names	Polr3k
Domain Architecture
Description	DNA-directed RNA polymerases III 12.5 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit K) (RNA polymerase III C11 subunit).

UBQL3_MOUSE
θ value	0.62314 (rank : 44)	NC score	0.173873 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	120	Shared Neighborhood Hits	21
SwissProt Accessions	Q8C5U9	Gene names	Ubqln3
Domain Architecture
Description	Ubiquilin-3.

RD23B_MOUSE
θ value	0.813845 (rank : 45)	NC score	0.093175 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	189	Shared Neighborhood Hits	17
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

CAR14_MOUSE
θ value	1.06291 (rank : 46)	NC score	0.016903 (rank : 66)
Query Neighborhood Hits	65	Target Neighborhood Hits	526	Shared Neighborhood Hits	2
SwissProt Accessions	Q99KF0	Gene names	Card14, Bimp2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (Bcl10-interacting MAGUK protein 2) (Bimp2).

FBX43_MOUSE
θ value	1.06291 (rank : 47)	NC score	0.099086 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	40	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CDI2, Q4G0C8, Q8R0R1	Gene names	Fbxo43, Emi2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

RD23B_HUMAN
θ value	1.06291 (rank : 48)	NC score	0.092893 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	115	Shared Neighborhood Hits	16
SwissProt Accessions	P54727, Q8WUB0	Gene names	RAD23B
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (hHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

UCRP_MOUSE
θ value	1.38821 (rank : 49)	NC score	0.137523 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	28	Shared Neighborhood Hits	18
SwissProt Accessions	Q64339, Q8K0H3	Gene names	Isg15, G1p2, Ucrp
Domain Architecture
Description	Ubiquitin cross-reactive protein precursor (Interferon-stimulated protein 15) (IP17).

UBL7_HUMAN
θ value	2.36792 (rank : 50)	NC score	0.087298 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	41	Shared Neighborhood Hits	14
SwissProt Accessions	Q96S82, Q96I03	Gene names	UBL7, BMSCUBP
Domain Architecture
Description	Ubiquitin-like protein 7 (Ubiquitin-like protein SB132) (Bone marrow stromal cell ubiquitin-like protein) (BMSC-UbP).

UBL7_MOUSE
θ value	2.36792 (rank : 51)	NC score	0.088188 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	44	Shared Neighborhood Hits	15
SwissProt Accessions	Q91W67, Q9D7P5	Gene names	Ubl7
Domain Architecture
Description	Ubiquitin-like protein 7.

FBX5_HUMAN
θ value	3.0926 (rank : 52)	NC score	0.088651 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UKT4, Q8WV29, Q9UGC8	Gene names	FBXO5, EMI1, FBX5
Domain Architecture	No domain graphic available
Description	F-box only protein 5 (Early mitotic inhibitor 1).

FGR_HUMAN
θ value	3.0926 (rank : 53)	NC score	0.002641 (rank : 72)
Query Neighborhood Hits	65	Target Neighborhood Hits	1067	Shared Neighborhood Hits	4
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FGR_MOUSE
θ value	3.0926 (rank : 54)	NC score	0.002665 (rank : 71)
Query Neighborhood Hits	65	Target Neighborhood Hits	1069	Shared Neighborhood Hits	4
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FBX43_HUMAN
θ value	4.03905 (rank : 55)	NC score	0.090536 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	34	Shared Neighborhood Hits	11
SwissProt Accessions	Q4G163	Gene names	FBXO43, EMI2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

PDE3A_MOUSE
θ value	4.03905 (rank : 56)	NC score	0.009328 (rank : 68)
Query Neighborhood Hits	65	Target Neighborhood Hits	115	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0X4	Gene names	Pde3a
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

RPC11_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.073020 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2Y1, Q96S35	Gene names	POLR3K, RPC11
Domain Architecture
Description	DNA-directed RNA polymerases III 12.5 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit K) (RNA polymerase III C11 subunit) (HsC11p) (hRPC11).

ADA11_HUMAN
θ value	5.27518 (rank : 58)	NC score	0.006813 (rank : 69)
Query Neighborhood Hits	65	Target Neighborhood Hits	259	Shared Neighborhood Hits	3
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

NUMB_HUMAN
θ value	5.27518 (rank : 59)	NC score	0.019981 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	P49757, Q6NUQ7, Q86SY1, Q8WW73, Q9UBG1, Q9UEQ4, Q9UKE8, Q9UKE9, Q9UKF0, Q9UQJ4	Gene names	NUMB
Domain Architecture
Description	Protein numb homolog (h-Numb) (Protein S171).

NUMB_MOUSE
θ value	5.27518 (rank : 60)	NC score	0.019668 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	91	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZS3, P70422, Q8CIB1, Q9DC57, Q9QZR1, Q9QZS4	Gene names	Numb
Domain Architecture
Description	Protein numb homolog (m-Numb) (m-Nb).

ADA11_MOUSE
θ value	6.88961 (rank : 61)	NC score	0.006287 (rank : 70)
Query Neighborhood Hits	65	Target Neighborhood Hits	263	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

UHRF2_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.033686 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	269	Shared Neighborhood Hits	11
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	6.88961 (rank : 63)	NC score	0.032198 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	275	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

ZN544_HUMAN
θ value	6.88961 (rank : 64)	NC score	-0.002973 (rank : 73)
Query Neighborhood Hits	65	Target Neighborhood Hits	772	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NX49, Q9UEX4	Gene names	ZNF544
Domain Architecture	No domain graphic available
Description	Zinc finger protein 544.

2A5R_MOUSE
θ value	8.99809 (rank : 65)	NC score	0.011506 (rank : 67)
Query Neighborhood Hits	65	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z176	Gene names	Ppp2r3a, Ppp2r6
Domain Architecture	No domain graphic available
Description	Protein phosphatase 2A, 59 kDa regulatory subunit B (PP2A PR59) (PP2A B''-PR59).

BAT3_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.054339 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	490	Shared Neighborhood Hits	21
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BAT3_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.056288 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	518	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

CUL7_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.132908 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

RD23A_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.065310 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	73	Shared Neighborhood Hits	17
SwissProt Accessions	P54725	Gene names	RAD23A
Domain Architecture
Description	UV excision repair protein RAD23 homolog A (hHR23A).

RD23A_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.063014 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	84	Shared Neighborhood Hits	17
SwissProt Accessions	P54726	Gene names	Rad23a, Mhr23a
Domain Architecture
Description	UV excision repair protein RAD23 homolog A (mHR23A).

UBD_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.090692 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	26	Shared Neighborhood Hits	19
SwissProt Accessions	O15205, Q5SUK2, Q96EC7	Gene names	UBD, FAT10
Domain Architecture	No domain graphic available
Description	Ubiquitin D (Ubiquitin-like protein FAT10) (Diubiquitin).

UBD_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.076650 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	30	Shared Neighborhood Hits	19
SwissProt Accessions	P63072, Q9WV10	Gene names	Ubd, Fat10
Domain Architecture	No domain graphic available
Description	Ubiquitin D (Ubiquitin-like protein FAT10) (Diubiquitin).

UCRP_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.095591 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	26	Shared Neighborhood Hits	13
SwissProt Accessions	P05161, Q7Z2G2, Q96GF0	Gene names	ISG15, G1P2, UCRP
Domain Architecture
Description	Interferon-induced 17 kDa protein precursor [Contains: Ubiquitin cross-reactive protein (hUCRP) (Interferon-induced 15 kDa protein)].

Hits sorted by NC score

PRKN2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	O60260, Q5TFV8, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07	Gene names	PARK2, PRKN
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2).

PRKN2_MOUSE
NC score	0.993965 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	69	Shared Neighborhood Hits	53
SwissProt Accessions	Q9WVS6, Q9ES22, Q9ES23	Gene names	Park2, Prkn
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN).

ARI1_HUMAN
NC score	0.668064 (rank : 3)	θ value	1.16975e-15 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	71	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y4X5, O76026, Q9H3T6, Q9UEN0, Q9UP39	Gene names	ARIH1, ARI, UBCH7BP
Domain Architecture
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6).

ARI1_MOUSE
NC score	0.667934 (rank : 4)	θ value	1.16975e-15 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	71	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z1K5, Q6PF92	Gene names	Arih1, Ari, Ubch7bp, Uip77
Domain Architecture	No domain graphic available
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein 77).

ARI2_MOUSE
NC score	0.654115 (rank : 5)	θ value	2.20605e-14 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	106	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

ARI2_HUMAN
NC score	0.653413 (rank : 6)	θ value	3.76295e-14 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	113	Shared Neighborhood Hits	26
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

RNF14_HUMAN
NC score	0.646656 (rank : 7)	θ value	6.41864e-14 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	70	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UBS8, O94793, Q6IBV0	Gene names	RNF14, ARA54
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein) (HFB30).

RNF14_MOUSE
NC score	0.639218 (rank : 8)	θ value	9.26847e-13 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	69	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JI90, Q9D0L2, Q9D6N2, Q9D6Z8, Q9JI89	Gene names	Rnf14, Ara54, Triad2
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein).

IBRD1_HUMAN
NC score	0.572802 (rank : 9)	θ value	2.21117e-06 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	62	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TC41, Q9BX48	Gene names	IBRDC1
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 1.

IBRD3_HUMAN
NC score	0.556366 (rank : 10)	θ value	8.97725e-08 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	70	Shared Neighborhood Hits	27
SwissProt Accessions	Q6ZMZ0, Q6P6A4	Gene names	IBRDC3
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 3.

UB7I4_HUMAN
NC score	0.553920 (rank : 11)	θ value	9.92553e-07 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	54	Shared Neighborhood Hits	24
SwissProt Accessions	P50876	Gene names	RNF144, KIAA0161, UBCE7IP4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

UB7I4_MOUSE
NC score	0.549502 (rank : 12)	θ value	4.92598e-06 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	59	Shared Neighborhood Hits	24
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

RNF19_MOUSE
NC score	0.528703 (rank : 13)	θ value	1.99992e-07 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	96	Shared Neighborhood Hits	28
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

RNF19_HUMAN
NC score	0.527296 (rank : 14)	θ value	1.99992e-07 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	105	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

IBRD2_MOUSE
NC score	0.523174 (rank : 15)	θ value	9.29e-05 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	46	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).

IBRD2_HUMAN
NC score	0.515899 (rank : 16)	θ value	0.000602161 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	55	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z419, Q6P4Q0, Q8N3R7, Q9BX38	Gene names	IBRDC2, P53RFP
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2) (p53-inducible RING finger protein).

PARC_HUMAN
NC score	0.499873 (rank : 17)	θ value	5.08577e-11 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	148	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

PARC_MOUSE
NC score	0.492443 (rank : 18)	θ value	1.9326e-10 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	114	Shared Neighborhood Hits	24
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

UB7I3_HUMAN
NC score	0.450344 (rank : 19)	θ value	3.19293e-05 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	136	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

UB7I3_MOUSE
NC score	0.445395 (rank : 20)	θ value	9.29e-05 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	131	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

RNF31_MOUSE
NC score	0.387873 (rank : 21)	θ value	0.00298849 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	113	Shared Neighborhood Hits	32
SwissProt Accessions	Q924T7	Gene names	Rnf31
Domain Architecture
Description	RING finger protein 31.

RNF31_HUMAN
NC score	0.387565 (rank : 22)	θ value	0.00390308 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	110	Shared Neighborhood Hits	31
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

UB7I1_HUMAN
NC score	0.378546 (rank : 23)	θ value	0.00298849 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	177	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

UB7I1_MOUSE
NC score	0.372632 (rank : 24)	θ value	0.00869519 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	206	Shared Neighborhood Hits	26
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

UBIQ_HUMAN
NC score	0.331745 (rank : 25)	θ value	4.92598e-06 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	49	Shared Neighborhood Hits	27
SwissProt Accessions	P62988, P02248, P02249, P02250, Q29120, Q6LBL4, Q6LDU5, Q91887, Q91888, Q9BWD6, Q9BX98, Q9UEF2, Q9UEG1, Q9UEK8, Q9UPK7	Gene names	RPS27A, UBA80, UBCEP1
Domain Architecture	No domain graphic available
Description	Ubiquitin.

UBIQ_MOUSE
NC score	0.331745 (rank : 26)	θ value	4.92598e-06 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	49	Shared Neighborhood Hits	27
SwissProt Accessions	P62991, P02248, P02249, P02250, Q29120, Q62317, Q64223, Q8VCH1, Q91887, Q91888, Q9CXY4, Q9CZM0, Q9D1R5, Q9D8D9, Q9ET23, Q9ET24, Q9Z0H9	Gene names	Rps27a, Uba80, Ubcep1
Domain Architecture	No domain graphic available
Description	Ubiquitin.

NEDD8_HUMAN
NC score	0.283032 (rank : 27)	θ value	0.00298849 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	40	Shared Neighborhood Hits	25
SwissProt Accessions	Q15843, Q6LES6	Gene names	NEDD8
Domain Architecture
Description	NEDD8 precursor (Ubiquitin-like protein Nedd8) (Neddylin).

NEDD8_MOUSE
NC score	0.282851 (rank : 28)	θ value	0.00298849 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	40	Shared Neighborhood Hits	25
SwissProt Accessions	P29595	Gene names	Nedd8, Nedd-8
Domain Architecture
Description	NEDD8 precursor (Ubiquitin-like protein Nedd8) (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8).

UBL4A_HUMAN
NC score	0.198194 (rank : 29)	θ value	0.163984 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	P11441	Gene names	UBL4A, DXS254E, GDX, UBL4
Domain Architecture
Description	Ubiquitin-like protein 4A (Ubiquitin-like protein GDX).

UBQL3_HUMAN
NC score	0.193494 (rank : 30)	θ value	0.0252991 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	141	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H347, Q9NRE0	Gene names	UBQLN3
Domain Architecture
Description	Ubiquilin-3.

UBQL1_HUMAN
NC score	0.193107 (rank : 31)	θ value	0.0252991 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	72	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UMX0, Q8IXS9, Q8N2Q3, Q9H0T8, Q9H3R4, Q9HAZ5	Gene names	UBQLN1, DA41, PLIC1
Domain Architecture
Description	Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC- 1).

UBQL1_MOUSE
NC score	0.191614 (rank : 32)	θ value	0.0252991 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	86	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R317, Q80V10, Q8C7T4, Q8C835, Q8K141, Q91VI8, Q9D0Z0, Q9QZM1	Gene names	Ubqln1, Plic1
Domain Architecture
Description	Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1).

UBIM_MOUSE
NC score	0.191230 (rank : 33)	θ value	0.21417 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	P35545, Q9JJ24	Gene names	Fau
Domain Architecture
Description	Ubiquitin-like protein FUBI (Monoclonal nonspecific suppressor factor beta) (MNSF-beta).

UBQL2_HUMAN
NC score	0.189989 (rank : 34)	θ value	0.00665767 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	103	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UHD9, O94798, Q9H3W6, Q9HAZ4	Gene names	UBQLN2, PLIC2
Domain Architecture
Description	Ubiquilin-2 (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC- 2) (Ubiquitin-like product Chap1/Dsk2) (DSK2 homolog) (Chap1).

UBIM_HUMAN
NC score	0.188748 (rank : 35)	θ value	0.21417 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	19	Shared Neighborhood Hits	11
SwissProt Accessions	P35544, Q9H5V4	Gene names	FAU
Domain Architecture
Description	Ubiquitin-like protein FUBI.

UBL4A_MOUSE
NC score	0.186058 (rank : 36)	θ value	0.21417 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	38	Shared Neighborhood Hits	22
SwissProt Accessions	P21126	Gene names	Ubl4a, Gdx, Ubl4
Domain Architecture
Description	Ubiquitin-like protein 4A (Ubiquitin-like protein GDX).

UBQL4_HUMAN
NC score	0.185949 (rank : 37)	θ value	0.0736092 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	117	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NRR5, Q9BR98, Q9UHX4	Gene names	UBQLN4, C1orf6, UBIN
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

UBQL4_MOUSE
NC score	0.182590 (rank : 38)	θ value	0.0431538 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	99	Shared Neighborhood Hits	23
SwissProt Accessions	Q99NB8, Q8BP88	Gene names	Ubqln4, Ubin
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

UBQL2_MOUSE
NC score	0.181914 (rank : 39)	θ value	0.0431538 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	114	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QZM0, Q7TSJ8, Q8VDH9	Gene names	Ubqln2, Plic2
Domain Architecture
Description	Ubiquilin-2 (Protein linking IAP with cytoskeleton 2) (PLIC-2) (Ubiquitin-like product Chap1/Dsk2) (DSK2 homolog) (Chap1).

UBQL3_MOUSE
NC score	0.173873 (rank : 40)	θ value	0.62314 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	120	Shared Neighborhood Hits	21
SwissProt Accessions	Q8C5U9	Gene names	Ubqln3
Domain Architecture
Description	Ubiquilin-3.

SUMO1_HUMAN
NC score	0.172556 (rank : 41)	θ value	0.00869519 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P63165, P55856, Q6FGG0, Q6NZ62, Q93068	Gene names	SUMO1, SMT3C, SMT3H3, UBL1
Domain Architecture	No domain graphic available
Description	Small ubiquitin-related modifier 1 precursor (SUMO-1) (Ubiquitin-like protein SMT3C) (SMT3 homolog 3) (Ubiquitin-homology domain protein PIC1) (Ubiquitin-like protein UBL1) (GAP-modifying protein 1) (GMP1) (Sentrin).

SUMO1_MOUSE
NC score	0.172556 (rank : 42)	θ value	0.00869519 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P63166, P55856, Q3TX92, Q93068	Gene names	Sumo1, Smt3c, Smt3h3, Ubl1
Domain Architecture	No domain graphic available
Description	Small ubiquitin-related modifier 1 precursor (SUMO-1) (Ubiquitin-like protein SMT3C) (SMT3 homolog 3) (Ubiquitin-homology domain protein PIC1).

UCRP_MOUSE
NC score	0.137523 (rank : 43)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	28	Shared Neighborhood Hits	18
SwissProt Accessions	Q64339, Q8K0H3	Gene names	Isg15, G1p2, Ucrp
Domain Architecture
Description	Ubiquitin cross-reactive protein precursor (Interferon-stimulated protein 15) (IP17).

CUL7_HUMAN
NC score	0.132908 (rank : 44)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	65	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

RPC11_MOUSE
NC score	0.101275 (rank : 45)	θ value	0.47712 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CQZ7, Q9D1U1	Gene names	Polr3k
Domain Architecture
Description	DNA-directed RNA polymerases III 12.5 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit K) (RNA polymerase III C11 subunit).

FBX43_MOUSE
NC score	0.099086 (rank : 46)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	40	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CDI2, Q4G0C8, Q8R0R1	Gene names	Fbxo43, Emi2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

UCRP_HUMAN
NC score	0.095591 (rank : 47)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	65	Target Neighborhood Hits	26	Shared Neighborhood Hits	13
SwissProt Accessions	P05161, Q7Z2G2, Q96GF0	Gene names	ISG15, G1P2, UCRP
Domain Architecture
Description	Interferon-induced 17 kDa protein precursor [Contains: Ubiquitin cross-reactive protein (hUCRP) (Interferon-induced 15 kDa protein)].

RD23B_MOUSE
NC score	0.093175 (rank : 48)	θ value	0.813845 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	189	Shared Neighborhood Hits	17
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

RD23B_HUMAN
NC score	0.092893 (rank : 49)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	115	Shared Neighborhood Hits	16
SwissProt Accessions	P54727, Q8WUB0	Gene names	RAD23B
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (hHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

UBD_HUMAN
NC score	0.090692 (rank : 50)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	65	Target Neighborhood Hits	26	Shared Neighborhood Hits	19
SwissProt Accessions	O15205, Q5SUK2, Q96EC7	Gene names	UBD, FAT10
Domain Architecture	No domain graphic available
Description	Ubiquitin D (Ubiquitin-like protein FAT10) (Diubiquitin).

FBX43_HUMAN
NC score	0.090536 (rank : 51)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	34	Shared Neighborhood Hits	11
SwissProt Accessions	Q4G163	Gene names	FBXO43, EMI2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

FBX5_HUMAN
NC score	0.088651 (rank : 52)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UKT4, Q8WV29, Q9UGC8	Gene names	FBXO5, EMI1, FBX5
Domain Architecture	No domain graphic available
Description	F-box only protein 5 (Early mitotic inhibitor 1).

UBL7_MOUSE
NC score	0.088188 (rank : 53)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	44	Shared Neighborhood Hits	15
SwissProt Accessions	Q91W67, Q9D7P5	Gene names	Ubl7
Domain Architecture
Description	Ubiquitin-like protein 7.

UBL7_HUMAN
NC score	0.087298 (rank : 54)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	41	Shared Neighborhood Hits	14
SwissProt Accessions	Q96S82, Q96I03	Gene names	UBL7, BMSCUBP
Domain Architecture
Description	Ubiquitin-like protein 7 (Ubiquitin-like protein SB132) (Bone marrow stromal cell ubiquitin-like protein) (BMSC-UbP).

UBD_MOUSE
NC score	0.076650 (rank : 55)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	65	Target Neighborhood Hits	30	Shared Neighborhood Hits	19
SwissProt Accessions	P63072, Q9WV10	Gene names	Ubd, Fat10
Domain Architecture	No domain graphic available
Description	Ubiquitin D (Ubiquitin-like protein FAT10) (Diubiquitin).

RPC11_HUMAN
NC score	0.073020 (rank : 56)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2Y1, Q96S35	Gene names	POLR3K, RPC11
Domain Architecture
Description	DNA-directed RNA polymerases III 12.5 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit K) (RNA polymerase III C11 subunit) (HsC11p) (hRPC11).

RD23A_HUMAN
NC score	0.065310 (rank : 57)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	65	Target Neighborhood Hits	73	Shared Neighborhood Hits	17
SwissProt Accessions	P54725	Gene names	RAD23A
Domain Architecture
Description	UV excision repair protein RAD23 homolog A (hHR23A).

RD23A_MOUSE
NC score	0.063014 (rank : 58)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	65	Target Neighborhood Hits	84	Shared Neighborhood Hits	17
SwissProt Accessions	P54726	Gene names	Rad23a, Mhr23a
Domain Architecture
Description	UV excision repair protein RAD23 homolog A (mHR23A).

BAT3_MOUSE
NC score	0.056288 (rank : 59)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	65	Target Neighborhood Hits	518	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

BAT3_HUMAN
NC score	0.054339 (rank : 60)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	65	Target Neighborhood Hits	490	Shared Neighborhood Hits	21
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

MLL2_HUMAN
NC score	0.045092 (rank : 61)	θ value	0.0961366 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	1788	Shared Neighborhood Hits	15
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

UHRF2_HUMAN
NC score	0.033686 (rank : 62)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	269	Shared Neighborhood Hits	11
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
NC score	0.032198 (rank : 63)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	275	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

NUMB_HUMAN
NC score	0.019981 (rank : 64)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	P49757, Q6NUQ7, Q86SY1, Q8WW73, Q9UBG1, Q9UEQ4, Q9UKE8, Q9UKE9, Q9UKF0, Q9UQJ4	Gene names	NUMB
Domain Architecture
Description	Protein numb homolog (h-Numb) (Protein S171).

NUMB_MOUSE
NC score	0.019668 (rank : 65)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	91	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZS3, P70422, Q8CIB1, Q9DC57, Q9QZR1, Q9QZS4	Gene names	Numb
Domain Architecture
Description	Protein numb homolog (m-Numb) (m-Nb).

CAR14_MOUSE
NC score	0.016903 (rank : 66)	θ value	1.06291 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	526	Shared Neighborhood Hits	2
SwissProt Accessions	Q99KF0	Gene names	Card14, Bimp2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (Bcl10-interacting MAGUK protein 2) (Bimp2).

2A5R_MOUSE
NC score	0.011506 (rank : 67)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z176	Gene names	Ppp2r3a, Ppp2r6
Domain Architecture	No domain graphic available
Description	Protein phosphatase 2A, 59 kDa regulatory subunit B (PP2A PR59) (PP2A B''-PR59).

PDE3A_MOUSE
NC score	0.009328 (rank : 68)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	115	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0X4	Gene names	Pde3a
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

ADA11_HUMAN
NC score	0.006813 (rank : 69)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	259	Shared Neighborhood Hits	3
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_MOUSE
NC score	0.006287 (rank : 70)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	263	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

FGR_MOUSE
NC score	0.002665 (rank : 71)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	1069	Shared Neighborhood Hits	4
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FGR_HUMAN
NC score	0.002641 (rank : 72)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	1067	Shared Neighborhood Hits	4
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

ZN544_HUMAN
NC score	-0.002973 (rank : 73)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	772	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NX49, Q9UEX4	Gene names	ZNF544
Domain Architecture	No domain graphic available
Description	Zinc finger protein 544.