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Network neighborhood for query Sequence : FBX43_MOUSE

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FBX43_MOUSE
SwissProt Accessions	Q8CDI2, Q4G0C8, Q8R0R1	Gene names	Fbxo43, Emi2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FBX43_HUMAN
θ value	0 (rank : 1)	NC score	0.982421 (rank : 2)
Query Neighborhood Hits	40	Target Neighborhood Hits	34	Shared Neighborhood Hits	12
SwissProt Accessions	Q4G163	Gene names	FBXO43, EMI2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

FBX43_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q8CDI2, Q4G0C8, Q8R0R1	Gene names	Fbxo43, Emi2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

FBX5_HUMAN
θ value	6.82597e-32 (rank : 3)	NC score	0.765551 (rank : 3)
Query Neighborhood Hits	40	Target Neighborhood Hits	29	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKT4, Q8WV29, Q9UGC8	Gene names	FBXO5, EMI1, FBX5
Domain Architecture	No domain graphic available
Description	F-box only protein 5 (Early mitotic inhibitor 1).

RNF14_HUMAN
θ value	0.000121331 (rank : 4)	NC score	0.206062 (rank : 4)
Query Neighborhood Hits	40	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UBS8, O94793, Q6IBV0	Gene names	RNF14, ARA54
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein) (HFB30).

RNF14_MOUSE
θ value	0.000461057 (rank : 5)	NC score	0.198197 (rank : 5)
Query Neighborhood Hits	40	Target Neighborhood Hits	69	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JI90, Q9D0L2, Q9D6N2, Q9D6Z8, Q9JI89	Gene names	Rnf14, Ara54, Triad2
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein).

CE110_HUMAN
θ value	0.125558 (rank : 6)	NC score	0.059057 (rank : 13)
Query Neighborhood Hits	40	Target Neighborhood Hits	197	Shared Neighborhood Hits	2
SwissProt Accessions	O43303, O43335, Q68DV9, Q8NE13	Gene names	CEP110, CP110, KIAA0419
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 110 kDa (Cep110 protein).

BRWD1_MOUSE
θ value	0.21417 (rank : 7)	NC score	0.028159 (rank : 23)
Query Neighborhood Hits	40	Target Neighborhood Hits	478	Shared Neighborhood Hits	6
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

RNF19_HUMAN
θ value	0.47712 (rank : 8)	NC score	0.112563 (rank : 7)
Query Neighborhood Hits	40	Target Neighborhood Hits	105	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

RNF19_MOUSE
θ value	0.47712 (rank : 9)	NC score	0.112902 (rank : 6)
Query Neighborhood Hits	40	Target Neighborhood Hits	96	Shared Neighborhood Hits	12
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

DSPP_HUMAN
θ value	0.62314 (rank : 10)	NC score	0.029515 (rank : 22)
Query Neighborhood Hits	40	Target Neighborhood Hits	645	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

SPAG1_HUMAN
θ value	0.813845 (rank : 11)	NC score	0.026295 (rank : 24)
Query Neighborhood Hits	40	Target Neighborhood Hits	197	Shared Neighborhood Hits	2
SwissProt Accessions	Q07617, Q7Z5G1	Gene names	SPAG1
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (HSD-3.8).

PRKN2_HUMAN
θ value	1.06291 (rank : 12)	NC score	0.099086 (rank : 9)
Query Neighborhood Hits	40	Target Neighborhood Hits	65	Shared Neighborhood Hits	12
SwissProt Accessions	O60260, Q5TFV8, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07	Gene names	PARK2, PRKN
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2).

IBRD3_HUMAN
θ value	1.38821 (rank : 13)	NC score	0.108263 (rank : 8)
Query Neighborhood Hits	40	Target Neighborhood Hits	70	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZMZ0, Q6P6A4	Gene names	IBRDC3
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 3.

MRP9_MOUSE
θ value	1.38821 (rank : 14)	NC score	0.012302 (rank : 40)
Query Neighborhood Hits	40	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	Q80WJ6, Q80WJ2, Q80WJ3, Q8C0P3	Gene names	Abcc12, Mrp9
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 9 (ATP-binding cassette transporter sub-family C member 12).

CF153_HUMAN
θ value	1.81305 (rank : 15)	NC score	0.058202 (rank : 14)
Query Neighborhood Hits	40	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	Q96EU6, Q9BRF6, Q9P0C8	Gene names	C6orf153
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf153.

CF153_MOUSE
θ value	2.36792 (rank : 16)	NC score	0.054656 (rank : 20)
Query Neighborhood Hits	40	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	Q3UFY0, Q91X71	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf153 homolog.

TBC12_HUMAN
θ value	2.36792 (rank : 17)	NC score	0.022226 (rank : 27)
Query Neighborhood Hits	40	Target Neighborhood Hits	80	Shared Neighborhood Hits	2
SwissProt Accessions	O60347, Q5VYA6, Q8WX26, Q8WX59, Q9UG83	Gene names	TBC1D12, KIAA0608
Domain Architecture
Description	TBC1 domain family member 12.

AIM1_HUMAN
θ value	4.03905 (rank : 18)	NC score	0.018213 (rank : 31)
Query Neighborhood Hits	40	Target Neighborhood Hits	247	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

FBW1B_HUMAN
θ value	4.03905 (rank : 19)	NC score	0.019382 (rank : 29)
Query Neighborhood Hits	40	Target Neighborhood Hits	327	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKB1, Q9P2S8, Q9P2S9, Q9Y4C6	Gene names	FBXW11, BTRCP2, FBW1B, FBXW1B, KIAA0696
Domain Architecture
Description	F-box/WD repeat protein 11 (F-box/WD repeat protein 1B) (F-box and WD repeats protein beta-TrCP2).

ZN638_HUMAN
θ value	4.03905 (rank : 20)	NC score	0.019450 (rank : 28)
Query Neighborhood Hits	40	Target Neighborhood Hits	343	Shared Neighborhood Hits	2
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

ARI2_HUMAN
θ value	5.27518 (rank : 21)	NC score	0.066618 (rank : 11)
Query Neighborhood Hits	40	Target Neighborhood Hits	113	Shared Neighborhood Hits	10
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

RPGF5_MOUSE
θ value	5.27518 (rank : 22)	NC score	0.012780 (rank : 39)
Query Neighborhood Hits	40	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C0Q9, Q8BJJ9, Q8C0R5	Gene names	Rapgef5, Gfr, Kiaa0277, Mrgef
Domain Architecture
Description	Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (M-Ras-regulated Rap GEF) (MR-GEF).

UBP34_HUMAN
θ value	5.27518 (rank : 23)	NC score	0.012863 (rank : 38)
Query Neighborhood Hits	40	Target Neighborhood Hits	210	Shared Neighborhood Hits	4
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

ARI2_MOUSE
θ value	6.88961 (rank : 24)	NC score	0.065213 (rank : 12)
Query Neighborhood Hits	40	Target Neighborhood Hits	106	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

MAGB3_HUMAN
θ value	6.88961 (rank : 25)	NC score	0.006999 (rank : 43)
Query Neighborhood Hits	40	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	O15480, O75861	Gene names	MAGEB3
Domain Architecture
Description	Melanoma-associated antigen B3 (MAGE-B3 antigen).

PMS2_HUMAN
θ value	6.88961 (rank : 26)	NC score	0.017624 (rank : 32)
Query Neighborhood Hits	40	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

PRKN2_MOUSE
θ value	6.88961 (rank : 27)	NC score	0.095778 (rank : 10)
Query Neighborhood Hits	40	Target Neighborhood Hits	69	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WVS6, Q9ES22, Q9ES23	Gene names	Park2, Prkn
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN).

DBR1_MOUSE
θ value	8.99809 (rank : 28)	NC score	0.015940 (rank : 35)
Query Neighborhood Hits	40	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q923B1, Q8C1T9, Q8C7J7, Q99MT1	Gene names	Dbr1
Domain Architecture	No domain graphic available
Description	Lariat debranching enzyme (EC 3.1.-.-).

FBW1A_HUMAN
θ value	8.99809 (rank : 29)	NC score	0.018640 (rank : 30)
Query Neighborhood Hits	40	Target Neighborhood Hits	329	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y297, Q9Y213	Gene names	BTRC, BTRCP, FBW1A, FBXW1A
Domain Architecture
Description	F-box/WD repeat protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit).

GBRE_HUMAN
θ value	8.99809 (rank : 30)	NC score	0.004257 (rank : 44)
Query Neighborhood Hits	40	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	P78334, O15345, O15346, Q99520	Gene names	GABRE
Domain Architecture
Description	Gamma-aminobutyric-acid receptor subunit epsilon precursor (GABA(A) receptor subunit epsilon).

GOGA2_HUMAN
θ value	8.99809 (rank : 31)	NC score	0.004037 (rank : 45)
Query Neighborhood Hits	40	Target Neighborhood Hits	856	Shared Neighborhood Hits	3
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

HPS5_HUMAN
θ value	8.99809 (rank : 32)	NC score	0.013484 (rank : 37)
Query Neighborhood Hits	40	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UPZ3, O95942, Q8N4U0	Gene names	HPS5, AIBP63, KIAA1017
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 5 protein (Alpha-integrin-binding protein 63) (Ruby-eye protein 2 homolog) (Ru2).

LAMA5_MOUSE
θ value	8.99809 (rank : 33)	NC score	0.003214 (rank : 46)
Query Neighborhood Hits	40	Target Neighborhood Hits	828	Shared Neighborhood Hits	3
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LBC_HUMAN
θ value	8.99809 (rank : 34)	NC score	0.008238 (rank : 42)
Query Neighborhood Hits	40	Target Neighborhood Hits	90	Shared Neighborhood Hits	2
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

NGLY1_HUMAN
θ value	8.99809 (rank : 35)	NC score	0.014715 (rank : 36)
Query Neighborhood Hits	40	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q96IV0, Q59FB1, Q6PJD8, Q9BVR8, Q9NR70	Gene names	NGLY1, PNG1
Domain Architecture	No domain graphic available
Description	Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (EC 3.5.1.52) (PNGase) (hPNGase) (Peptide:N-glycanase) (N-glycanase 1).

NRBF2_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.022436 (rank : 25)
Query Neighborhood Hits	40	Target Neighborhood Hits	122	Shared Neighborhood Hits	4
SwissProt Accessions	Q96F24, Q86UR2, Q96NP6, Q9H0S9, Q9H2I2	Gene names	NRBF2, COPR
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding factor 2 (NRBF-2) (Comodulator of PPAR and RXR).

NRBF2_MOUSE
θ value	8.99809 (rank : 37)	NC score	0.022347 (rank : 26)
Query Neighborhood Hits	40	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VCQ3, Q9DCG3	Gene names	Nrbf2
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding factor 2 (NRBF-2).

PAPPA_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.008839 (rank : 41)
Query Neighborhood Hits	40	Target Neighborhood Hits	161	Shared Neighborhood Hits	2
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PCY1B_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.016719 (rank : 33)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5K3, O60621, Q86XC9	Gene names	PCYT1B, CCTB
Domain Architecture
Description	Choline-phosphate cytidylyltransferase B (EC 2.7.7.15) (Phosphorylcholine transferase B) (CTP:phosphocholine cytidylyltransferase B) (CT B) (CCT B) (CCT-beta).

PCY1B_MOUSE
θ value	8.99809 (rank : 40)	NC score	0.016692 (rank : 34)
Query Neighborhood Hits	40	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q811Q9, Q3UEW0, Q80Y63, Q811Q8, Q8BKD2, Q8C085	Gene names	Pcyt1b
Domain Architecture	No domain graphic available
Description	Choline-phosphate cytidylyltransferase B (EC 2.7.7.15) (Phosphorylcholine transferase B) (CTP:phosphocholine cytidylyltransferase B) (CT B) (CCT B) (CCT-beta).

ARI1_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.056915 (rank : 15)
Query Neighborhood Hits	40	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y4X5, O76026, Q9H3T6, Q9UEN0, Q9UP39	Gene names	ARIH1, ARI, UBCH7BP
Domain Architecture
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6).

ARI1_MOUSE
θ value	θ > 10 (rank : 42)	NC score	0.056903 (rank : 16)
Query Neighborhood Hits	40	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z1K5, Q6PF92	Gene names	Arih1, Ari, Ubch7bp, Uip77
Domain Architecture	No domain graphic available
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein 77).

IBRD2_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.056743 (rank : 17)
Query Neighborhood Hits	40	Target Neighborhood Hits	55	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z419, Q6P4Q0, Q8N3R7, Q9BX38	Gene names	IBRDC2, P53RFP
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2) (p53-inducible RING finger protein).

IBRD2_MOUSE
θ value	θ > 10 (rank : 44)	NC score	0.053978 (rank : 21)
Query Neighborhood Hits	40	Target Neighborhood Hits	46	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).

UB7I4_HUMAN
θ value	θ > 10 (rank : 45)	NC score	0.055001 (rank : 19)
Query Neighborhood Hits	40	Target Neighborhood Hits	54	Shared Neighborhood Hits	9
SwissProt Accessions	P50876	Gene names	RNF144, KIAA0161, UBCE7IP4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

UB7I4_MOUSE
θ value	θ > 10 (rank : 46)	NC score	0.055329 (rank : 18)
Query Neighborhood Hits	40	Target Neighborhood Hits	59	Shared Neighborhood Hits	9
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

Hits sorted by NC score

FBX43_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q8CDI2, Q4G0C8, Q8R0R1	Gene names	Fbxo43, Emi2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

FBX43_HUMAN
NC score	0.982421 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	40	Target Neighborhood Hits	34	Shared Neighborhood Hits	12
SwissProt Accessions	Q4G163	Gene names	FBXO43, EMI2
Domain Architecture	No domain graphic available
Description	F-box only protein 43 (Endogenous meiotic inhibitor 2).

FBX5_HUMAN
NC score	0.765551 (rank : 3)	θ value	6.82597e-32 (rank : 3)
Query Neighborhood Hits	40	Target Neighborhood Hits	29	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKT4, Q8WV29, Q9UGC8	Gene names	FBXO5, EMI1, FBX5
Domain Architecture	No domain graphic available
Description	F-box only protein 5 (Early mitotic inhibitor 1).

RNF14_HUMAN
NC score	0.206062 (rank : 4)	θ value	0.000121331 (rank : 4)
Query Neighborhood Hits	40	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UBS8, O94793, Q6IBV0	Gene names	RNF14, ARA54
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein) (HFB30).

RNF14_MOUSE
NC score	0.198197 (rank : 5)	θ value	0.000461057 (rank : 5)
Query Neighborhood Hits	40	Target Neighborhood Hits	69	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JI90, Q9D0L2, Q9D6N2, Q9D6Z8, Q9JI89	Gene names	Rnf14, Ara54, Triad2
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein).

RNF19_MOUSE
NC score	0.112902 (rank : 6)	θ value	0.47712 (rank : 9)
Query Neighborhood Hits	40	Target Neighborhood Hits	96	Shared Neighborhood Hits	12
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

RNF19_HUMAN
NC score	0.112563 (rank : 7)	θ value	0.47712 (rank : 8)
Query Neighborhood Hits	40	Target Neighborhood Hits	105	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

IBRD3_HUMAN
NC score	0.108263 (rank : 8)	θ value	1.38821 (rank : 13)
Query Neighborhood Hits	40	Target Neighborhood Hits	70	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZMZ0, Q6P6A4	Gene names	IBRDC3
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 3.

PRKN2_HUMAN
NC score	0.099086 (rank : 9)	θ value	1.06291 (rank : 12)
Query Neighborhood Hits	40	Target Neighborhood Hits	65	Shared Neighborhood Hits	12
SwissProt Accessions	O60260, Q5TFV8, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07	Gene names	PARK2, PRKN
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2).

PRKN2_MOUSE
NC score	0.095778 (rank : 10)	θ value	6.88961 (rank : 27)
Query Neighborhood Hits	40	Target Neighborhood Hits	69	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WVS6, Q9ES22, Q9ES23	Gene names	Park2, Prkn
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN).

ARI2_HUMAN
NC score	0.066618 (rank : 11)	θ value	5.27518 (rank : 21)
Query Neighborhood Hits	40	Target Neighborhood Hits	113	Shared Neighborhood Hits	10
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

ARI2_MOUSE
NC score	0.065213 (rank : 12)	θ value	6.88961 (rank : 24)
Query Neighborhood Hits	40	Target Neighborhood Hits	106	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

CE110_HUMAN
NC score	0.059057 (rank : 13)	θ value	0.125558 (rank : 6)
Query Neighborhood Hits	40	Target Neighborhood Hits	197	Shared Neighborhood Hits	2
SwissProt Accessions	O43303, O43335, Q68DV9, Q8NE13	Gene names	CEP110, CP110, KIAA0419
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 110 kDa (Cep110 protein).

CF153_HUMAN
NC score	0.058202 (rank : 14)	θ value	1.81305 (rank : 15)
Query Neighborhood Hits	40	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	Q96EU6, Q9BRF6, Q9P0C8	Gene names	C6orf153
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf153.

ARI1_HUMAN
NC score	0.056915 (rank : 15)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	40	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y4X5, O76026, Q9H3T6, Q9UEN0, Q9UP39	Gene names	ARIH1, ARI, UBCH7BP
Domain Architecture
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6).

ARI1_MOUSE
NC score	0.056903 (rank : 16)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	40	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z1K5, Q6PF92	Gene names	Arih1, Ari, Ubch7bp, Uip77
Domain Architecture	No domain graphic available
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein 77).

IBRD2_HUMAN
NC score	0.056743 (rank : 17)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	40	Target Neighborhood Hits	55	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z419, Q6P4Q0, Q8N3R7, Q9BX38	Gene names	IBRDC2, P53RFP
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2) (p53-inducible RING finger protein).

UB7I4_MOUSE
NC score	0.055329 (rank : 18)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	40	Target Neighborhood Hits	59	Shared Neighborhood Hits	9
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

UB7I4_HUMAN
NC score	0.055001 (rank : 19)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	40	Target Neighborhood Hits	54	Shared Neighborhood Hits	9
SwissProt Accessions	P50876	Gene names	RNF144, KIAA0161, UBCE7IP4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

CF153_MOUSE
NC score	0.054656 (rank : 20)	θ value	2.36792 (rank : 16)
Query Neighborhood Hits	40	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	Q3UFY0, Q91X71	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf153 homolog.

IBRD2_MOUSE
NC score	0.053978 (rank : 21)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	40	Target Neighborhood Hits	46	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).

DSPP_HUMAN
NC score	0.029515 (rank : 22)	θ value	0.62314 (rank : 10)
Query Neighborhood Hits	40	Target Neighborhood Hits	645	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

BRWD1_MOUSE
NC score	0.028159 (rank : 23)	θ value	0.21417 (rank : 7)
Query Neighborhood Hits	40	Target Neighborhood Hits	478	Shared Neighborhood Hits	6
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

SPAG1_HUMAN
NC score	0.026295 (rank : 24)	θ value	0.813845 (rank : 11)
Query Neighborhood Hits	40	Target Neighborhood Hits	197	Shared Neighborhood Hits	2
SwissProt Accessions	Q07617, Q7Z5G1	Gene names	SPAG1
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (HSD-3.8).

NRBF2_HUMAN
NC score	0.022436 (rank : 25)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	40	Target Neighborhood Hits	122	Shared Neighborhood Hits	4
SwissProt Accessions	Q96F24, Q86UR2, Q96NP6, Q9H0S9, Q9H2I2	Gene names	NRBF2, COPR
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding factor 2 (NRBF-2) (Comodulator of PPAR and RXR).

NRBF2_MOUSE
NC score	0.022347 (rank : 26)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	40	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VCQ3, Q9DCG3	Gene names	Nrbf2
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding factor 2 (NRBF-2).

TBC12_HUMAN
NC score	0.022226 (rank : 27)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	40	Target Neighborhood Hits	80	Shared Neighborhood Hits	2
SwissProt Accessions	O60347, Q5VYA6, Q8WX26, Q8WX59, Q9UG83	Gene names	TBC1D12, KIAA0608
Domain Architecture
Description	TBC1 domain family member 12.

ZN638_HUMAN
NC score	0.019450 (rank : 28)	θ value	4.03905 (rank : 20)
Query Neighborhood Hits	40	Target Neighborhood Hits	343	Shared Neighborhood Hits	2
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

FBW1B_HUMAN
NC score	0.019382 (rank : 29)	θ value	4.03905 (rank : 19)
Query Neighborhood Hits	40	Target Neighborhood Hits	327	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKB1, Q9P2S8, Q9P2S9, Q9Y4C6	Gene names	FBXW11, BTRCP2, FBW1B, FBXW1B, KIAA0696
Domain Architecture
Description	F-box/WD repeat protein 11 (F-box/WD repeat protein 1B) (F-box and WD repeats protein beta-TrCP2).

FBW1A_HUMAN
NC score	0.018640 (rank : 30)	θ value	8.99809 (rank : 29)
Query Neighborhood Hits	40	Target Neighborhood Hits	329	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y297, Q9Y213	Gene names	BTRC, BTRCP, FBW1A, FBXW1A
Domain Architecture
Description	F-box/WD repeat protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit).

AIM1_HUMAN
NC score	0.018213 (rank : 31)	θ value	4.03905 (rank : 18)
Query Neighborhood Hits	40	Target Neighborhood Hits	247	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

PMS2_HUMAN
NC score	0.017624 (rank : 32)	θ value	6.88961 (rank : 26)
Query Neighborhood Hits	40	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

PCY1B_HUMAN
NC score	0.016719 (rank : 33)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5K3, O60621, Q86XC9	Gene names	PCYT1B, CCTB
Domain Architecture
Description	Choline-phosphate cytidylyltransferase B (EC 2.7.7.15) (Phosphorylcholine transferase B) (CTP:phosphocholine cytidylyltransferase B) (CT B) (CCT B) (CCT-beta).

PCY1B_MOUSE
NC score	0.016692 (rank : 34)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	40	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q811Q9, Q3UEW0, Q80Y63, Q811Q8, Q8BKD2, Q8C085	Gene names	Pcyt1b
Domain Architecture	No domain graphic available
Description	Choline-phosphate cytidylyltransferase B (EC 2.7.7.15) (Phosphorylcholine transferase B) (CTP:phosphocholine cytidylyltransferase B) (CT B) (CCT B) (CCT-beta).

DBR1_MOUSE
NC score	0.015940 (rank : 35)	θ value	8.99809 (rank : 28)
Query Neighborhood Hits	40	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q923B1, Q8C1T9, Q8C7J7, Q99MT1	Gene names	Dbr1
Domain Architecture	No domain graphic available
Description	Lariat debranching enzyme (EC 3.1.-.-).

NGLY1_HUMAN
NC score	0.014715 (rank : 36)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	40	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q96IV0, Q59FB1, Q6PJD8, Q9BVR8, Q9NR70	Gene names	NGLY1, PNG1
Domain Architecture	No domain graphic available
Description	Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (EC 3.5.1.52) (PNGase) (hPNGase) (Peptide:N-glycanase) (N-glycanase 1).

HPS5_HUMAN
NC score	0.013484 (rank : 37)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	40	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UPZ3, O95942, Q8N4U0	Gene names	HPS5, AIBP63, KIAA1017
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 5 protein (Alpha-integrin-binding protein 63) (Ruby-eye protein 2 homolog) (Ru2).

UBP34_HUMAN
NC score	0.012863 (rank : 38)	θ value	5.27518 (rank : 23)
Query Neighborhood Hits	40	Target Neighborhood Hits	210	Shared Neighborhood Hits	4
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

RPGF5_MOUSE
NC score	0.012780 (rank : 39)	θ value	5.27518 (rank : 22)
Query Neighborhood Hits	40	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C0Q9, Q8BJJ9, Q8C0R5	Gene names	Rapgef5, Gfr, Kiaa0277, Mrgef
Domain Architecture
Description	Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (M-Ras-regulated Rap GEF) (MR-GEF).

MRP9_MOUSE
NC score	0.012302 (rank : 40)	θ value	1.38821 (rank : 14)
Query Neighborhood Hits	40	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	Q80WJ6, Q80WJ2, Q80WJ3, Q8C0P3	Gene names	Abcc12, Mrp9
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 9 (ATP-binding cassette transporter sub-family C member 12).

PAPPA_HUMAN
NC score	0.008839 (rank : 41)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	40	Target Neighborhood Hits	161	Shared Neighborhood Hits	2
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

LBC_HUMAN
NC score	0.008238 (rank : 42)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	40	Target Neighborhood Hits	90	Shared Neighborhood Hits	2
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

MAGB3_HUMAN
NC score	0.006999 (rank : 43)	θ value	6.88961 (rank : 25)
Query Neighborhood Hits	40	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	O15480, O75861	Gene names	MAGEB3
Domain Architecture
Description	Melanoma-associated antigen B3 (MAGE-B3 antigen).

GBRE_HUMAN
NC score	0.004257 (rank : 44)	θ value	8.99809 (rank : 30)
Query Neighborhood Hits	40	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	P78334, O15345, O15346, Q99520	Gene names	GABRE
Domain Architecture
Description	Gamma-aminobutyric-acid receptor subunit epsilon precursor (GABA(A) receptor subunit epsilon).

GOGA2_HUMAN
NC score	0.004037 (rank : 45)	θ value	8.99809 (rank : 31)
Query Neighborhood Hits	40	Target Neighborhood Hits	856	Shared Neighborhood Hits	3
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

LAMA5_MOUSE
NC score	0.003214 (rank : 46)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	40	Target Neighborhood Hits	828	Shared Neighborhood Hits	3
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.