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Network neighborhood for query Sequence : CJ064_HUMAN

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CJ064_HUMAN
SwissProt Accessions	Q6ZS81, Q8N4A3	Gene names	C10orf64
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf64.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CJ064_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q6ZS81, Q8N4A3	Gene names	C10orf64
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf64.

WDFY3_MOUSE
θ value	3.4333e-100 (rank : 2)	NC score	0.531665 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	332	Shared Neighborhood Hits	3
SwissProt Accessions	Q6VNB8, Q8C8H7	Gene names	Wdfy3
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1).

WDFY3_HUMAN
θ value	1.30465e-99 (rank : 3)	NC score	0.529847 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	348	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

SUMF1_MOUSE
θ value	1.38821 (rank : 4)	NC score	0.034563 (rank : 53)
Query Neighborhood Hits	19	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R0F3	Gene names	Sumf1, Fge
Domain Architecture
Description	Sulfatase-modifying factor 1 precursor (C-alpha-formyglycine- generating enzyme 1).

AATF_MOUSE
θ value	3.0926 (rank : 5)	NC score	0.030761 (rank : 55)
Query Neighborhood Hits	19	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JKX4, Q7TQN1, Q8C5Q2, Q99P89	Gene names	Aatf, Che1, Trb
Domain Architecture	No domain graphic available
Description	Protein AATF (Apoptosis-antagonizing transcription factor) (Rb-binding protein Che-1) (Traube protein).

CLN3_MOUSE
θ value	3.0926 (rank : 6)	NC score	0.031671 (rank : 54)
Query Neighborhood Hits	19	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q61124, P70400	Gene names	Cln3
Domain Architecture
Description	Protein CLN3 (Battenin).

M4A6D_MOUSE
θ value	3.0926 (rank : 7)	NC score	0.022974 (rank : 56)
Query Neighborhood Hits	19	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q99N07, Q9D0X1, Q9EQY7	Gene names	Ms4a6d, Cd20l8, Ms4a11
Domain Architecture
Description	Membrane-spanning 4-domains subfamily A member 6D (CD20 antigen-like 8).

PGFRB_MOUSE
θ value	4.03905 (rank : 8)	NC score	0.003523 (rank : 67)
Query Neighborhood Hits	19	Target Neighborhood Hits	960	Shared Neighborhood Hits	2
SwissProt Accessions	P05622	Gene names	Pdgfrb, Pdgfr
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

TAP2_MOUSE
θ value	4.03905 (rank : 9)	NC score	0.008874 (rank : 64)
Query Neighborhood Hits	19	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	P36371	Gene names	Tap2, Abcb3, Ham-2, Ham2
Domain Architecture
Description	Antigen peptide transporter 2 (APT2) (ATP-binding cassette sub-family B member 3) (Histocompatibility antigen modifier 2).

SOX18_HUMAN
θ value	5.27518 (rank : 10)	NC score	0.009998 (rank : 63)
Query Neighborhood Hits	19	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	P35713, Q9NPH8	Gene names	SOX18
Domain Architecture
Description	Transcription factor SOX-18.

ARMX2_MOUSE
θ value	6.88961 (rank : 11)	NC score	0.011264 (rank : 62)
Query Neighborhood Hits	19	Target Neighborhood Hits	349	Shared Neighborhood Hits	3
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

VTDB_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.015621 (rank : 59)
Query Neighborhood Hits	19	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	P02774, Q16309, Q16310	Gene names	GC
Domain Architecture
Description	Vitamin D-binding protein precursor (DBP) (Group-specific component) (Gc-globulin) (VDB).

COT2_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.005530 (rank : 65)
Query Neighborhood Hits	19	Target Neighborhood Hits	135	Shared Neighborhood Hits	3
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT2_MOUSE
θ value	8.99809 (rank : 14)	NC score	0.005530 (rank : 66)
Query Neighborhood Hits	19	Target Neighborhood Hits	135	Shared Neighborhood Hits	3
SwissProt Accessions	P43135	Gene names	Nr2f2, Aporp1, Arp-1, Arp1, Tfcoup2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

LMA2L_MOUSE
θ value	8.99809 (rank : 15)	NC score	0.011315 (rank : 61)
Query Neighborhood Hits	19	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P59481, Q3TZ91	Gene names	Lman2l, Vipl
Domain Architecture
Description	VIP36-like protein precursor (Lectin, mannose-binding 2-like) (LMAN2- like protein).

PLD2_MOUSE
θ value	8.99809 (rank : 16)	NC score	0.011623 (rank : 60)
Query Neighborhood Hits	19	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	P97813	Gene names	Pld2
Domain Architecture
Description	Phospholipase D2 (EC 3.1.4.4) (PLD 2) (Choline phosphatase 2) (Phosphatidylcholine-hydrolyzing phospholipase D2) (PLD1C) (mPLD2).

SALL3_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.001566 (rank : 68)
Query Neighborhood Hits	19	Target Neighborhood Hits	1066	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

SF3B1_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.017600 (rank : 57)
Query Neighborhood Hits	19	Target Neighborhood Hits	341	Shared Neighborhood Hits	4
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.017578 (rank : 58)
Query Neighborhood Hits	19	Target Neighborhood Hits	352	Shared Neighborhood Hits	4
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

FAN_HUMAN
θ value	θ > 10 (rank : 20)	NC score	0.164520 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	295	Shared Neighborhood Hits	2
SwissProt Accessions	Q92636	Gene names	NSMAF, FAN
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

FAN_MOUSE
θ value	θ > 10 (rank : 21)	NC score	0.169520 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	292	Shared Neighborhood Hits	2
SwissProt Accessions	O35242	Gene names	Nsmaf, Fan
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

FGD2_HUMAN
θ value	θ > 10 (rank : 22)	NC score	0.052960 (rank : 50)
Query Neighborhood Hits	19	Target Neighborhood Hits	151	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

FGD2_MOUSE
θ value	θ > 10 (rank : 23)	NC score	0.054683 (rank : 46)
Query Neighborhood Hits	19	Target Neighborhood Hits	163	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

FGD5_HUMAN
θ value	θ > 10 (rank : 24)	NC score	0.055717 (rank : 44)
Query Neighborhood Hits	19	Target Neighborhood Hits	235	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

FGD5_MOUSE
θ value	θ > 10 (rank : 25)	NC score	0.061869 (rank : 41)
Query Neighborhood Hits	19	Target Neighborhood Hits	170	Shared Neighborhood Hits	2
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

FGD6_HUMAN
θ value	θ > 10 (rank : 26)	NC score	0.060722 (rank : 42)
Query Neighborhood Hits	19	Target Neighborhood Hits	237	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD6_MOUSE
θ value	θ > 10 (rank : 27)	NC score	0.054963 (rank : 45)
Query Neighborhood Hits	19	Target Neighborhood Hits	282	Shared Neighborhood Hits	2
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

FYV1_HUMAN
θ value	θ > 10 (rank : 28)	NC score	0.068730 (rank : 34)
Query Neighborhood Hits	19	Target Neighborhood Hits	217	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

FYV1_MOUSE
θ value	θ > 10 (rank : 29)	NC score	0.068853 (rank : 33)
Query Neighborhood Hits	19	Target Neighborhood Hits	191	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

HGS_HUMAN
θ value	θ > 10 (rank : 30)	NC score	0.085885 (rank : 23)
Query Neighborhood Hits	19	Target Neighborhood Hits	517	Shared Neighborhood Hits	2
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HGS_MOUSE
θ value	θ > 10 (rank : 31)	NC score	0.084876 (rank : 25)
Query Neighborhood Hits	19	Target Neighborhood Hits	589	Shared Neighborhood Hits	2
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

IF122_HUMAN
θ value	θ > 10 (rank : 32)	NC score	0.064911 (rank : 38)
Query Neighborhood Hits	19	Target Neighborhood Hits	244	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HBG6	Gene names	IFT122, WDR10, WDR140
Domain Architecture
Description	Intraflagellar transport 122 homolog (WD repeat protein 10).

LRBA_HUMAN
θ value	θ > 10 (rank : 33)	NC score	0.208695 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	196	Shared Neighborhood Hits	2
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

LYST_HUMAN
θ value	θ > 10 (rank : 34)	NC score	0.214253 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	324	Shared Neighborhood Hits	2
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

LYST_MOUSE
θ value	θ > 10 (rank : 35)	NC score	0.218407 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	286	Shared Neighborhood Hits	2
SwissProt Accessions	P97412, Q62403, Q8VBS6	Gene names	Lyst, Bg, Chs1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog).

MTMR3_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.066050 (rank : 37)
Query Neighborhood Hits	19	Target Neighborhood Hits	163	Shared Neighborhood Hits	2
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

NBEAL_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.250668 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	200	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZS30, Q6Y876, Q6ZQY5, Q96Q30	Gene names	NBEAL1, ALS2CR17
Domain Architecture	No domain graphic available
Description	Neurobeachin-like 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein).

NBEA_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.203816 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	186	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NFP9, Q9HCM8, Q9NSU1, Q9NW98, Q9Y6J1	Gene names	NBEA, BCL8B, KIAA1544, LYST2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B).

NBEA_MOUSE
θ value	θ > 10 (rank : 39)	NC score	0.202148 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	225	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EPN1, Q8C931, Q9EPM9, Q9EPN0, Q9WVM9	Gene names	Nbea, Lyst2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2).

PK1IP_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.054040 (rank : 48)
Query Neighborhood Hits	19	Target Neighborhood Hits	277	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NWT1, Q5T4J2, Q96QJ8, Q96T87	Gene names	PAK1IP1, PIP1, WDR84
Domain Architecture	No domain graphic available
Description	p21-activated protein kinase-interacting protein 1 (PAK1-interacting protein 1) (PAK/PLC-interacting protein 1) (hPIP1) (WD repeat protein 84).

PKHF1_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.104255 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

PKHF1_MOUSE
θ value	θ > 10 (rank : 42)	NC score	0.103389 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	80	Shared Neighborhood Hits	2
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

PKHF2_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.072680 (rank : 31)
Query Neighborhood Hits	19	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

PKHF2_MOUSE
θ value	θ > 10 (rank : 44)	NC score	0.072466 (rank : 32)
Query Neighborhood Hits	19	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

RBNS5_HUMAN
θ value	θ > 10 (rank : 45)	NC score	0.083430 (rank : 26)
Query Neighborhood Hits	19	Target Neighborhood Hits	242	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

RBNS5_MOUSE
θ value	θ > 10 (rank : 46)	NC score	0.080876 (rank : 28)
Query Neighborhood Hits	19	Target Neighborhood Hits	266	Shared Neighborhood Hits	2
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

RUFY1_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.053957 (rank : 49)
Query Neighborhood Hits	19	Target Neighborhood Hits	848	Shared Neighborhood Hits	2
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

RUFY1_MOUSE
θ value	θ > 10 (rank : 48)	NC score	0.054510 (rank : 47)
Query Neighborhood Hits	19	Target Neighborhood Hits	765	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

RUFY2_MOUSE
θ value	θ > 10 (rank : 49)	NC score	0.056115 (rank : 43)
Query Neighborhood Hits	19	Target Neighborhood Hits	820	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

WDFY1_HUMAN
θ value	θ > 10 (rank : 50)	NC score	0.067763 (rank : 35)
Query Neighborhood Hits	19	Target Neighborhood Hits	305	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IWB7, Q9H9D5, Q9P2B3	Gene names	WDFY1, KIAA1435, WDF1, ZFYVE17
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 1 (WD40- and FYVE domain- containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain-containing protein 17).

WDFY2_HUMAN
θ value	θ > 10 (rank : 51)	NC score	0.063341 (rank : 40)
Query Neighborhood Hits	19	Target Neighborhood Hits	332	Shared Neighborhood Hits	2
SwissProt Accessions	Q96P53, Q96CS1	Gene names	WDFY2, WDF2, ZFYVE22
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2) (Zinc finger FYVE domain-containing protein 22).

WDFY2_MOUSE
θ value	θ > 10 (rank : 52)	NC score	0.064330 (rank : 39)
Query Neighborhood Hits	19	Target Neighborhood Hits	337	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BUB4	Gene names	Wdfy2
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2).

WDR16_HUMAN
θ value	θ > 10 (rank : 53)	NC score	0.050005 (rank : 52)
Query Neighborhood Hits	19	Target Neighborhood Hits	275	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N1V2, Q5DX23, Q8TC73, Q8TCI3	Gene names	WDR16, WDRPUH
Domain Architecture	No domain graphic available
Description	WD repeat protein 16 (WD40-repeat protein up-regulated in HCC).

WDR54_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.066592 (rank : 36)
Query Neighborhood Hits	19	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H977, Q53H85, Q86V45	Gene names	WDR54
Domain Architecture	No domain graphic available
Description	WD repeat protein 54.

WDR54_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.097194 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	96	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0D8, Q3U4A4	Gene names	Wdr54, D3Mm3e
Domain Architecture	No domain graphic available
Description	WD repeat protein 54.

WDR72_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.051926 (rank : 51)
Query Neighborhood Hits	19	Target Neighborhood Hits	167	Shared Neighborhood Hits	2
SwissProt Accessions	Q3MJ13, Q7Z3I3, Q8N8X2	Gene names	WDR72
Domain Architecture	No domain graphic available
Description	WD repeat protein 72.

ZFY16_HUMAN
θ value	θ > 10 (rank : 57)	NC score	0.078945 (rank : 30)
Query Neighborhood Hits	19	Target Neighborhood Hits	125	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

ZFY16_MOUSE
θ value	θ > 10 (rank : 58)	NC score	0.080971 (rank : 27)
Query Neighborhood Hits	19	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

ZFY19_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.090112 (rank : 20)
Query Neighborhood Hits	19	Target Neighborhood Hits	206	Shared Neighborhood Hits	2
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

ZFY19_MOUSE
θ value	θ > 10 (rank : 60)	NC score	0.100988 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	143	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DAZ9, Q8VCV7	Gene names	Zfyve19
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19.

ZFY21_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.108228 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BQ24, Q86T05, Q96LT1	Gene names	ZFYVE21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY21_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.110316 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VCM3, Q9D1E2	Gene names	Zfyve21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY27_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.092516 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	64	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T4F4, Q5T4F1, Q5T4F2, Q5T4F3, Q8N1K0, Q8N6D6, Q8NCA0, Q8NDE4, Q96M08	Gene names	ZFYVE27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

ZFY27_MOUSE
θ value	θ > 10 (rank : 64)	NC score	0.088599 (rank : 21)
Query Neighborhood Hits	19	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q3TXX3, Q8CFP8	Gene names	Zfyve27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

ZFY28_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.117123 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	152	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

ZFYV1_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.088445 (rank : 22)
Query Neighborhood Hits	19	Target Neighborhood Hits	166	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

ZFYV1_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.085139 (rank : 24)
Query Neighborhood Hits	19	Target Neighborhood Hits	153	Shared Neighborhood Hits	2
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

ZFYV9_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.080233 (rank : 29)
Query Neighborhood Hits	19	Target Neighborhood Hits	134	Shared Neighborhood Hits	2
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

Hits sorted by NC score

CJ064_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q6ZS81, Q8N4A3	Gene names	C10orf64
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf64.

WDFY3_MOUSE
NC score	0.531665 (rank : 2)	θ value	3.4333e-100 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	332	Shared Neighborhood Hits	3
SwissProt Accessions	Q6VNB8, Q8C8H7	Gene names	Wdfy3
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1).

WDFY3_HUMAN
NC score	0.529847 (rank : 3)	θ value	1.30465e-99 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	348	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

NBEAL_HUMAN
NC score	0.250668 (rank : 4)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	19	Target Neighborhood Hits	200	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZS30, Q6Y876, Q6ZQY5, Q96Q30	Gene names	NBEAL1, ALS2CR17
Domain Architecture	No domain graphic available
Description	Neurobeachin-like 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein).

LYST_MOUSE
NC score	0.218407 (rank : 5)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	19	Target Neighborhood Hits	286	Shared Neighborhood Hits	2
SwissProt Accessions	P97412, Q62403, Q8VBS6	Gene names	Lyst, Bg, Chs1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog).

LYST_HUMAN
NC score	0.214253 (rank : 6)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	19	Target Neighborhood Hits	324	Shared Neighborhood Hits	2
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

LRBA_HUMAN
NC score	0.208695 (rank : 7)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	19	Target Neighborhood Hits	196	Shared Neighborhood Hits	2
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

NBEA_HUMAN
NC score	0.203816 (rank : 8)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	19	Target Neighborhood Hits	186	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NFP9, Q9HCM8, Q9NSU1, Q9NW98, Q9Y6J1	Gene names	NBEA, BCL8B, KIAA1544, LYST2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B).

NBEA_MOUSE
NC score	0.202148 (rank : 9)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	19	Target Neighborhood Hits	225	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EPN1, Q8C931, Q9EPM9, Q9EPN0, Q9WVM9	Gene names	Nbea, Lyst2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2).

FAN_MOUSE
NC score	0.169520 (rank : 10)	θ value	θ > 10 (rank : 21)
Query Neighborhood Hits	19	Target Neighborhood Hits	292	Shared Neighborhood Hits	2
SwissProt Accessions	O35242	Gene names	Nsmaf, Fan
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

FAN_HUMAN
NC score	0.164520 (rank : 11)	θ value	θ > 10 (rank : 20)
Query Neighborhood Hits	19	Target Neighborhood Hits	295	Shared Neighborhood Hits	2
SwissProt Accessions	Q92636	Gene names	NSMAF, FAN
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

ZFY28_HUMAN
NC score	0.117123 (rank : 12)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	19	Target Neighborhood Hits	152	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

ZFY21_MOUSE
NC score	0.110316 (rank : 13)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	19	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VCM3, Q9D1E2	Gene names	Zfyve21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY21_HUMAN
NC score	0.108228 (rank : 14)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	19	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BQ24, Q86T05, Q96LT1	Gene names	ZFYVE21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

PKHF1_HUMAN
NC score	0.104255 (rank : 15)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	19	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

PKHF1_MOUSE
NC score	0.103389 (rank : 16)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	19	Target Neighborhood Hits	80	Shared Neighborhood Hits	2
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

ZFY19_MOUSE
NC score	0.100988 (rank : 17)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	19	Target Neighborhood Hits	143	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DAZ9, Q8VCV7	Gene names	Zfyve19
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19.

WDR54_MOUSE
NC score	0.097194 (rank : 18)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	19	Target Neighborhood Hits	96	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0D8, Q3U4A4	Gene names	Wdr54, D3Mm3e
Domain Architecture	No domain graphic available
Description	WD repeat protein 54.

ZFY27_HUMAN
NC score	0.092516 (rank : 19)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	19	Target Neighborhood Hits	64	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T4F4, Q5T4F1, Q5T4F2, Q5T4F3, Q8N1K0, Q8N6D6, Q8NCA0, Q8NDE4, Q96M08	Gene names	ZFYVE27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

ZFY19_HUMAN
NC score	0.090112 (rank : 20)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	19	Target Neighborhood Hits	206	Shared Neighborhood Hits	2
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

ZFY27_MOUSE
NC score	0.088599 (rank : 21)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	19	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q3TXX3, Q8CFP8	Gene names	Zfyve27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

ZFYV1_HUMAN
NC score	0.088445 (rank : 22)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	19	Target Neighborhood Hits	166	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

HGS_HUMAN
NC score	0.085885 (rank : 23)	θ value	θ > 10 (rank : 30)
Query Neighborhood Hits	19	Target Neighborhood Hits	517	Shared Neighborhood Hits	2
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

ZFYV1_MOUSE
NC score	0.085139 (rank : 24)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	19	Target Neighborhood Hits	153	Shared Neighborhood Hits	2
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

HGS_MOUSE
NC score	0.084876 (rank : 25)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	19	Target Neighborhood Hits	589	Shared Neighborhood Hits	2
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

RBNS5_HUMAN
NC score	0.083430 (rank : 26)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	19	Target Neighborhood Hits	242	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

ZFY16_MOUSE
NC score	0.080971 (rank : 27)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	19	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

RBNS5_MOUSE
NC score	0.080876 (rank : 28)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	19	Target Neighborhood Hits	266	Shared Neighborhood Hits	2
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

ZFYV9_HUMAN
NC score	0.080233 (rank : 29)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	19	Target Neighborhood Hits	134	Shared Neighborhood Hits	2
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

ZFY16_HUMAN
NC score	0.078945 (rank : 30)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	19	Target Neighborhood Hits	125	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

PKHF2_HUMAN
NC score	0.072680 (rank : 31)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	19	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

PKHF2_MOUSE
NC score	0.072466 (rank : 32)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	19	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

FYV1_MOUSE
NC score	0.068853 (rank : 33)	θ value	θ > 10 (rank : 29)
Query Neighborhood Hits	19	Target Neighborhood Hits	191	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

FYV1_HUMAN
NC score	0.068730 (rank : 34)	θ value	θ > 10 (rank : 28)
Query Neighborhood Hits	19	Target Neighborhood Hits	217	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

WDFY1_HUMAN
NC score	0.067763 (rank : 35)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	19	Target Neighborhood Hits	305	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IWB7, Q9H9D5, Q9P2B3	Gene names	WDFY1, KIAA1435, WDF1, ZFYVE17
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 1 (WD40- and FYVE domain- containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain-containing protein 17).

WDR54_HUMAN
NC score	0.066592 (rank : 36)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	19	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H977, Q53H85, Q86V45	Gene names	WDR54
Domain Architecture	No domain graphic available
Description	WD repeat protein 54.

MTMR3_HUMAN
NC score	0.066050 (rank : 37)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	19	Target Neighborhood Hits	163	Shared Neighborhood Hits	2
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

IF122_HUMAN
NC score	0.064911 (rank : 38)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	19	Target Neighborhood Hits	244	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HBG6	Gene names	IFT122, WDR10, WDR140
Domain Architecture
Description	Intraflagellar transport 122 homolog (WD repeat protein 10).

WDFY2_MOUSE
NC score	0.064330 (rank : 39)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	19	Target Neighborhood Hits	337	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BUB4	Gene names	Wdfy2
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2).

WDFY2_HUMAN
NC score	0.063341 (rank : 40)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	19	Target Neighborhood Hits	332	Shared Neighborhood Hits	2
SwissProt Accessions	Q96P53, Q96CS1	Gene names	WDFY2, WDF2, ZFYVE22
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2) (Zinc finger FYVE domain-containing protein 22).

FGD5_MOUSE
NC score	0.061869 (rank : 41)	θ value	θ > 10 (rank : 25)
Query Neighborhood Hits	19	Target Neighborhood Hits	170	Shared Neighborhood Hits	2
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

FGD6_HUMAN
NC score	0.060722 (rank : 42)	θ value	θ > 10 (rank : 26)
Query Neighborhood Hits	19	Target Neighborhood Hits	237	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

RUFY2_MOUSE
NC score	0.056115 (rank : 43)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	19	Target Neighborhood Hits	820	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

FGD5_HUMAN
NC score	0.055717 (rank : 44)	θ value	θ > 10 (rank : 24)
Query Neighborhood Hits	19	Target Neighborhood Hits	235	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

FGD6_MOUSE
NC score	0.054963 (rank : 45)	θ value	θ > 10 (rank : 27)
Query Neighborhood Hits	19	Target Neighborhood Hits	282	Shared Neighborhood Hits	2
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

FGD2_MOUSE
NC score	0.054683 (rank : 46)	θ value	θ > 10 (rank : 23)
Query Neighborhood Hits	19	Target Neighborhood Hits	163	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

RUFY1_MOUSE
NC score	0.054510 (rank : 47)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	19	Target Neighborhood Hits	765	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

PK1IP_HUMAN
NC score	0.054040 (rank : 48)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	19	Target Neighborhood Hits	277	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NWT1, Q5T4J2, Q96QJ8, Q96T87	Gene names	PAK1IP1, PIP1, WDR84
Domain Architecture	No domain graphic available
Description	p21-activated protein kinase-interacting protein 1 (PAK1-interacting protein 1) (PAK/PLC-interacting protein 1) (hPIP1) (WD repeat protein 84).

RUFY1_HUMAN
NC score	0.053957 (rank : 49)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	19	Target Neighborhood Hits	848	Shared Neighborhood Hits	2
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

FGD2_HUMAN
NC score	0.052960 (rank : 50)	θ value	θ > 10 (rank : 22)
Query Neighborhood Hits	19	Target Neighborhood Hits	151	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

WDR72_HUMAN
NC score	0.051926 (rank : 51)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	19	Target Neighborhood Hits	167	Shared Neighborhood Hits	2
SwissProt Accessions	Q3MJ13, Q7Z3I3, Q8N8X2	Gene names	WDR72
Domain Architecture	No domain graphic available
Description	WD repeat protein 72.

WDR16_HUMAN
NC score	0.050005 (rank : 52)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	19	Target Neighborhood Hits	275	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N1V2, Q5DX23, Q8TC73, Q8TCI3	Gene names	WDR16, WDRPUH
Domain Architecture	No domain graphic available
Description	WD repeat protein 16 (WD40-repeat protein up-regulated in HCC).

SUMF1_MOUSE
NC score	0.034563 (rank : 53)	θ value	1.38821 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R0F3	Gene names	Sumf1, Fge
Domain Architecture
Description	Sulfatase-modifying factor 1 precursor (C-alpha-formyglycine- generating enzyme 1).

CLN3_MOUSE
NC score	0.031671 (rank : 54)	θ value	3.0926 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q61124, P70400	Gene names	Cln3
Domain Architecture
Description	Protein CLN3 (Battenin).

AATF_MOUSE
NC score	0.030761 (rank : 55)	θ value	3.0926 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JKX4, Q7TQN1, Q8C5Q2, Q99P89	Gene names	Aatf, Che1, Trb
Domain Architecture	No domain graphic available
Description	Protein AATF (Apoptosis-antagonizing transcription factor) (Rb-binding protein Che-1) (Traube protein).

M4A6D_MOUSE
NC score	0.022974 (rank : 56)	θ value	3.0926 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q99N07, Q9D0X1, Q9EQY7	Gene names	Ms4a6d, Cd20l8, Ms4a11
Domain Architecture
Description	Membrane-spanning 4-domains subfamily A member 6D (CD20 antigen-like 8).

SF3B1_HUMAN
NC score	0.017600 (rank : 57)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	341	Shared Neighborhood Hits	4
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
NC score	0.017578 (rank : 58)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	352	Shared Neighborhood Hits	4
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

VTDB_HUMAN
NC score	0.015621 (rank : 59)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	P02774, Q16309, Q16310	Gene names	GC
Domain Architecture
Description	Vitamin D-binding protein precursor (DBP) (Group-specific component) (Gc-globulin) (VDB).

PLD2_MOUSE
NC score	0.011623 (rank : 60)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	P97813	Gene names	Pld2
Domain Architecture
Description	Phospholipase D2 (EC 3.1.4.4) (PLD 2) (Choline phosphatase 2) (Phosphatidylcholine-hydrolyzing phospholipase D2) (PLD1C) (mPLD2).

LMA2L_MOUSE
NC score	0.011315 (rank : 61)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P59481, Q3TZ91	Gene names	Lman2l, Vipl
Domain Architecture
Description	VIP36-like protein precursor (Lectin, mannose-binding 2-like) (LMAN2- like protein).

ARMX2_MOUSE
NC score	0.011264 (rank : 62)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	349	Shared Neighborhood Hits	3
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

SOX18_HUMAN
NC score	0.009998 (rank : 63)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	P35713, Q9NPH8	Gene names	SOX18
Domain Architecture
Description	Transcription factor SOX-18.

TAP2_MOUSE
NC score	0.008874 (rank : 64)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	P36371	Gene names	Tap2, Abcb3, Ham-2, Ham2
Domain Architecture
Description	Antigen peptide transporter 2 (APT2) (ATP-binding cassette sub-family B member 3) (Histocompatibility antigen modifier 2).

COT2_HUMAN
NC score	0.005530 (rank : 65)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	135	Shared Neighborhood Hits	3
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT2_MOUSE
NC score	0.005530 (rank : 66)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	135	Shared Neighborhood Hits	3
SwissProt Accessions	P43135	Gene names	Nr2f2, Aporp1, Arp-1, Arp1, Tfcoup2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

PGFRB_MOUSE
NC score	0.003523 (rank : 67)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	960	Shared Neighborhood Hits	2
SwissProt Accessions	P05622	Gene names	Pdgfrb, Pdgfr
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

SALL3_HUMAN
NC score	0.001566 (rank : 68)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	1066	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).