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Network neighborhood for query Sequence : ZFYV1_MOUSE

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ZFYV1_MOUSE
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ZFYV1_HUMAN
θ value	0 (rank : 1)	NC score	0.991138 (rank : 2)
Query Neighborhood Hits	153	Target Neighborhood Hits	166	Shared Neighborhood Hits	117
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

ZFYV1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	153	Target Neighborhood Hits	153	Shared Neighborhood Hits	153
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

RUFY1_HUMAN
θ value	2.0648e-12 (rank : 3)	NC score	0.384264 (rank : 27)
Query Neighborhood Hits	153	Target Neighborhood Hits	848	Shared Neighborhood Hits	67
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

RUFY1_MOUSE
θ value	7.84624e-12 (rank : 4)	NC score	0.389084 (rank : 24)
Query Neighborhood Hits	153	Target Neighborhood Hits	765	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

RUFY2_HUMAN
θ value	1.133e-10 (rank : 5)	NC score	0.302401 (rank : 43)
Query Neighborhood Hits	153	Target Neighborhood Hits	1208	Shared Neighborhood Hits	69
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

HGS_HUMAN
θ value	1.47974e-10 (rank : 6)	NC score	0.508096 (rank : 13)
Query Neighborhood Hits	153	Target Neighborhood Hits	517	Shared Neighborhood Hits	60
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HGS_MOUSE
θ value	1.47974e-10 (rank : 7)	NC score	0.505142 (rank : 14)
Query Neighborhood Hits	153	Target Neighborhood Hits	589	Shared Neighborhood Hits	61
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

ZFY28_HUMAN
θ value	1.47974e-10 (rank : 8)	NC score	0.647917 (rank : 3)
Query Neighborhood Hits	153	Target Neighborhood Hits	152	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

RUFY2_MOUSE
θ value	1.9326e-10 (rank : 9)	NC score	0.378516 (rank : 28)
Query Neighborhood Hits	153	Target Neighborhood Hits	820	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

MTMR3_HUMAN
θ value	7.34386e-10 (rank : 10)	NC score	0.375909 (rank : 31)
Query Neighborhood Hits	153	Target Neighborhood Hits	163	Shared Neighborhood Hits	55
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

EEA1_MOUSE
θ value	3.64472e-09 (rank : 11)	NC score	0.220745 (rank : 49)
Query Neighborhood Hits	153	Target Neighborhood Hits	1637	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

EEA1_HUMAN
θ value	4.76016e-09 (rank : 12)	NC score	0.204111 (rank : 50)
Query Neighborhood Hits	153	Target Neighborhood Hits	1796	Shared Neighborhood Hits	79
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

FYV1_HUMAN
θ value	6.21693e-09 (rank : 13)	NC score	0.476448 (rank : 16)
Query Neighborhood Hits	153	Target Neighborhood Hits	217	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

FYV1_MOUSE
θ value	6.21693e-09 (rank : 14)	NC score	0.476796 (rank : 15)
Query Neighborhood Hits	153	Target Neighborhood Hits	191	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

ZFY16_HUMAN
θ value	8.97725e-08 (rank : 15)	NC score	0.536831 (rank : 12)
Query Neighborhood Hits	153	Target Neighborhood Hits	125	Shared Neighborhood Hits	58
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

ZFY21_HUMAN
θ value	1.17247e-07 (rank : 16)	NC score	0.640384 (rank : 4)
Query Neighborhood Hits	153	Target Neighborhood Hits	72	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BQ24, Q86T05, Q96LT1	Gene names	ZFYVE21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

WDFY3_HUMAN
θ value	1.53129e-07 (rank : 17)	NC score	0.351132 (rank : 35)
Query Neighborhood Hits	153	Target Neighborhood Hits	348	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

WDFY3_MOUSE
θ value	1.53129e-07 (rank : 18)	NC score	0.352386 (rank : 34)
Query Neighborhood Hits	153	Target Neighborhood Hits	332	Shared Neighborhood Hits	56
SwissProt Accessions	Q6VNB8, Q8C8H7	Gene names	Wdfy3
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1).

ZFY21_MOUSE
θ value	1.53129e-07 (rank : 19)	NC score	0.639765 (rank : 5)
Query Neighborhood Hits	153	Target Neighborhood Hits	72	Shared Neighborhood Hits	59
SwissProt Accessions	Q8VCM3, Q9D1E2	Gene names	Zfyve21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

PKHF2_HUMAN
θ value	1.99992e-07 (rank : 20)	NC score	0.577077 (rank : 7)
Query Neighborhood Hits	153	Target Neighborhood Hits	75	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

PKHF2_MOUSE
θ value	1.99992e-07 (rank : 21)	NC score	0.577852 (rank : 6)
Query Neighborhood Hits	153	Target Neighborhood Hits	77	Shared Neighborhood Hits	48
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

WDFY1_HUMAN
θ value	3.41135e-07 (rank : 22)	NC score	0.386249 (rank : 26)
Query Neighborhood Hits	153	Target Neighborhood Hits	305	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IWB7, Q9H9D5, Q9P2B3	Gene names	WDFY1, KIAA1435, WDF1, ZFYVE17
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 1 (WD40- and FYVE domain- containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain-containing protein 17).

ZFY16_MOUSE
θ value	3.41135e-07 (rank : 23)	NC score	0.541200 (rank : 10)
Query Neighborhood Hits	153	Target Neighborhood Hits	108	Shared Neighborhood Hits	59
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

FYCO1_MOUSE
θ value	9.92553e-07 (rank : 24)	NC score	0.233854 (rank : 48)
Query Neighborhood Hits	153	Target Neighborhood Hits	1059	Shared Neighborhood Hits	61
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

WDFY2_HUMAN
θ value	1.29631e-06 (rank : 25)	NC score	0.376138 (rank : 30)
Query Neighborhood Hits	153	Target Neighborhood Hits	332	Shared Neighborhood Hits	50
SwissProt Accessions	Q96P53, Q96CS1	Gene names	WDFY2, WDF2, ZFYVE22
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2) (Zinc finger FYVE domain-containing protein 22).

WDFY2_MOUSE
θ value	1.69304e-06 (rank : 26)	NC score	0.378200 (rank : 29)
Query Neighborhood Hits	153	Target Neighborhood Hits	337	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BUB4	Gene names	Wdfy2
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2).

FGD6_HUMAN
θ value	2.21117e-06 (rank : 27)	NC score	0.418184 (rank : 19)
Query Neighborhood Hits	153	Target Neighborhood Hits	237	Shared Neighborhood Hits	51
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

PKHF1_HUMAN
θ value	2.88788e-06 (rank : 28)	NC score	0.567035 (rank : 8)
Query Neighborhood Hits	153	Target Neighborhood Hits	76	Shared Neighborhood Hits	51
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

ANFY1_MOUSE
θ value	3.77169e-06 (rank : 29)	NC score	0.236814 (rank : 46)
Query Neighborhood Hits	153	Target Neighborhood Hits	480	Shared Neighborhood Hits	56
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

FGD5_HUMAN
θ value	3.77169e-06 (rank : 30)	NC score	0.415563 (rank : 20)
Query Neighborhood Hits	153	Target Neighborhood Hits	235	Shared Neighborhood Hits	55
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

FYCO1_HUMAN
θ value	3.77169e-06 (rank : 31)	NC score	0.243297 (rank : 45)
Query Neighborhood Hits	153	Target Neighborhood Hits	1149	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

ZFYV9_HUMAN
θ value	4.92598e-06 (rank : 32)	NC score	0.537297 (rank : 11)
Query Neighborhood Hits	153	Target Neighborhood Hits	134	Shared Neighborhood Hits	54
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

ANFY1_HUMAN
θ value	6.43352e-06 (rank : 33)	NC score	0.235144 (rank : 47)
Query Neighborhood Hits	153	Target Neighborhood Hits	480	Shared Neighborhood Hits	54
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

FGD2_MOUSE
θ value	1.09739e-05 (rank : 34)	NC score	0.375532 (rank : 32)
Query Neighborhood Hits	153	Target Neighborhood Hits	163	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

FGD2_HUMAN
θ value	1.43324e-05 (rank : 35)	NC score	0.374588 (rank : 33)
Query Neighborhood Hits	153	Target Neighborhood Hits	151	Shared Neighborhood Hits	51
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

FGD6_MOUSE
θ value	1.43324e-05 (rank : 36)	NC score	0.403721 (rank : 22)
Query Neighborhood Hits	153	Target Neighborhood Hits	282	Shared Neighborhood Hits	51
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

PKHF1_MOUSE
θ value	4.1701e-05 (rank : 37)	NC score	0.554732 (rank : 9)
Query Neighborhood Hits	153	Target Neighborhood Hits	80	Shared Neighborhood Hits	51
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

FGD4_MOUSE
θ value	5.44631e-05 (rank : 38)	NC score	0.350389 (rank : 36)
Query Neighborhood Hits	153	Target Neighborhood Hits	227	Shared Neighborhood Hits	52
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

RBNS5_HUMAN
θ value	0.000121331 (rank : 39)	NC score	0.432498 (rank : 17)
Query Neighborhood Hits	153	Target Neighborhood Hits	242	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

RBNS5_MOUSE
θ value	0.000121331 (rank : 40)	NC score	0.428429 (rank : 18)
Query Neighborhood Hits	153	Target Neighborhood Hits	266	Shared Neighborhood Hits	54
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

FGD4_HUMAN
θ value	0.00035302 (rank : 41)	NC score	0.348820 (rank : 37)
Query Neighborhood Hits	153	Target Neighborhood Hits	219	Shared Neighborhood Hits	51
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD5_MOUSE
θ value	0.00134147 (rank : 42)	NC score	0.406857 (rank : 21)
Query Neighborhood Hits	153	Target Neighborhood Hits	170	Shared Neighborhood Hits	54
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

TRI25_HUMAN
θ value	0.00509761 (rank : 43)	NC score	0.066239 (rank : 73)
Query Neighborhood Hits	153	Target Neighborhood Hits	472	Shared Neighborhood Hits	18
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

FGD1_HUMAN
θ value	0.00665767 (rank : 44)	NC score	0.328665 (rank : 40)
Query Neighborhood Hits	153	Target Neighborhood Hits	367	Shared Neighborhood Hits	54
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_MOUSE
θ value	0.00665767 (rank : 45)	NC score	0.327297 (rank : 41)
Query Neighborhood Hits	153	Target Neighborhood Hits	387	Shared Neighborhood Hits	53
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

ZFAN1_HUMAN
θ value	0.0148317 (rank : 46)	NC score	0.082802 (rank : 62)
Query Neighborhood Hits	153	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TCF1, Q658R7, Q6IA32, Q6PGQ6, Q9H810	Gene names	ZFAND1
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 1.

ZFY19_HUMAN
θ value	0.0252991 (rank : 47)	NC score	0.396397 (rank : 23)
Query Neighborhood Hits	153	Target Neighborhood Hits	206	Shared Neighborhood Hits	60
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

GBP4_HUMAN
θ value	0.0431538 (rank : 48)	NC score	0.078057 (rank : 65)
Query Neighborhood Hits	153	Target Neighborhood Hits	484	Shared Neighborhood Hits	18
SwissProt Accessions	Q96PP9, Q86T99	Gene names	GBP4
Domain Architecture
Description	Guanylate-binding protein 4 (GTP-binding protein 4) (Guanine nucleotide-binding protein 4) (GBP-4).

OVOL1_MOUSE
θ value	0.0431538 (rank : 49)	NC score	0.051872 (rank : 96)
Query Neighborhood Hits	153	Target Neighborhood Hits	716	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WTJ2, Q545S2	Gene names	Ovol1
Domain Architecture	No domain graphic available
Description	Putative transcription factor Ovo-like 1 (mOvo1) (mOvo1a).

ZN295_HUMAN
θ value	0.0431538 (rank : 50)	NC score	0.056004 (rank : 85)
Query Neighborhood Hits	153	Target Neighborhood Hits	847	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ULJ3, Q6P4R0	Gene names	ZNF295, KIAA1227, ZBTB21
Domain Architecture
Description	Zinc finger protein 295 (Zinc finger and BTB domain-containing protein 21).

FGD3_HUMAN
θ value	0.0563607 (rank : 51)	NC score	0.307665 (rank : 42)
Query Neighborhood Hits	153	Target Neighborhood Hits	249	Shared Neighborhood Hits	60
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

ZFY27_HUMAN
θ value	0.0563607 (rank : 52)	NC score	0.335382 (rank : 38)
Query Neighborhood Hits	153	Target Neighborhood Hits	64	Shared Neighborhood Hits	46
SwissProt Accessions	Q5T4F4, Q5T4F1, Q5T4F2, Q5T4F3, Q8N1K0, Q8N6D6, Q8NCA0, Q8NDE4, Q96M08	Gene names	ZFYVE27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

ZFY27_MOUSE
θ value	0.0563607 (rank : 53)	NC score	0.335015 (rank : 39)
Query Neighborhood Hits	153	Target Neighborhood Hits	53	Shared Neighborhood Hits	44
SwissProt Accessions	Q3TXX3, Q8CFP8	Gene names	Zfyve27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

ZFY19_MOUSE
θ value	0.0736092 (rank : 54)	NC score	0.388244 (rank : 25)
Query Neighborhood Hits	153	Target Neighborhood Hits	143	Shared Neighborhood Hits	56
SwissProt Accessions	Q9DAZ9, Q8VCV7	Gene names	Zfyve19
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19.

ZN184_HUMAN
θ value	0.0736092 (rank : 55)	NC score	0.035037 (rank : 127)
Query Neighborhood Hits	153	Target Neighborhood Hits	811	Shared Neighborhood Hits	60
SwissProt Accessions	Q99676, O60792, Q8TBA9	Gene names	ZNF184
Domain Architecture
Description	Zinc finger protein 184.

TRI42_MOUSE
θ value	0.0961366 (rank : 56)	NC score	0.074115 (rank : 67)
Query Neighborhood Hits	153	Target Neighborhood Hits	316	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

ZFX_HUMAN
θ value	0.163984 (rank : 57)	NC score	0.045033 (rank : 109)
Query Neighborhood Hits	153	Target Neighborhood Hits	751	Shared Neighborhood Hits	56
SwissProt Accessions	P17010, O43668, Q8WYJ8	Gene names	ZFX
Domain Architecture
Description	Zinc finger X-chromosomal protein.

ZFA_MOUSE
θ value	0.279714 (rank : 58)	NC score	0.044441 (rank : 111)
Query Neighborhood Hits	153	Target Neighborhood Hits	746	Shared Neighborhood Hits	56
SwissProt Accessions	P23607	Gene names	Zfa
Domain Architecture
Description	Zinc finger autosomal protein.

ZFX_MOUSE
θ value	0.279714 (rank : 59)	NC score	0.044463 (rank : 110)
Query Neighborhood Hits	153	Target Neighborhood Hits	748	Shared Neighborhood Hits	56
SwissProt Accessions	P17012, P17011	Gene names	Zfx
Domain Architecture
Description	Zinc finger X-chromosomal protein.

ZN343_HUMAN
θ value	0.279714 (rank : 60)	NC score	0.035188 (rank : 126)
Query Neighborhood Hits	153	Target Neighborhood Hits	768	Shared Neighborhood Hits	58
SwissProt Accessions	Q6P1L6, Q5JXU8, Q5JXU9, Q8N8F2, Q96EX8, Q96NA5, Q9BQB0	Gene names	ZNF343
Domain Architecture	No domain graphic available
Description	Zinc finger protein 343.

GBP5_MOUSE
θ value	0.365318 (rank : 61)	NC score	0.065689 (rank : 74)
Query Neighborhood Hits	153	Target Neighborhood Hits	254	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CFB4, Q8CFA4	Gene names	Gbp5
Domain Architecture
Description	Interferon-induced guanylate-binding protein 5 (GTP-binding protein 5) (Guanine nucleotide-binding protein 5) (GBP-5) (MuGBP-5).

OVOL1_HUMAN
θ value	0.365318 (rank : 62)	NC score	0.047938 (rank : 105)
Query Neighborhood Hits	153	Target Neighborhood Hits	729	Shared Neighborhood Hits	58
SwissProt Accessions	O14753, Q6PCB1	Gene names	OVOL1
Domain Architecture	No domain graphic available
Description	Putative transcription factor Ovo-like 1 (hOvo1).

OVOL2_MOUSE
θ value	0.365318 (rank : 63)	NC score	0.047208 (rank : 106)
Query Neighborhood Hits	153	Target Neighborhood Hits	709	Shared Neighborhood Hits	55
SwissProt Accessions	Q8CIV7, Q6F661, Q8CIV6, Q8K0D6, Q9D949	Gene names	Ovol2, Ovo2, Zfp339, Znf339
Domain Architecture	No domain graphic available
Description	Transcription factor Ovo-like 2 (mOvo2) (Zinc finger protein 339) (Zinc finger OVO2) (Zinc finger protein mOVO).

PLAL2_HUMAN
θ value	0.365318 (rank : 64)	NC score	0.038461 (rank : 121)
Query Neighborhood Hits	153	Target Neighborhood Hits	734	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UPG8, Q92584	Gene names	PLAGL2, KIAA0198
Domain Architecture	No domain graphic available
Description	Zinc finger protein PLAGL2 (Pleiomorphic adenoma-like protein 2).

ZFY_HUMAN
θ value	0.365318 (rank : 65)	NC score	0.044039 (rank : 114)
Query Neighborhood Hits	153	Target Neighborhood Hits	752	Shared Neighborhood Hits	56
SwissProt Accessions	P08048, Q14021, Q15558, Q96TF3	Gene names	ZFY
Domain Architecture
Description	Zinc finger Y-chromosomal protein.

TRI42_HUMAN
θ value	0.62314 (rank : 66)	NC score	0.065310 (rank : 75)
Query Neighborhood Hits	153	Target Neighborhood Hits	283	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

ZN564_HUMAN
θ value	0.62314 (rank : 67)	NC score	0.034785 (rank : 131)
Query Neighborhood Hits	153	Target Neighborhood Hits	746	Shared Neighborhood Hits	58
SwissProt Accessions	Q8TBZ8	Gene names	ZNF564
Domain Architecture	No domain graphic available
Description	Zinc finger protein 564.

ZNF7_HUMAN
θ value	0.62314 (rank : 68)	NC score	0.033837 (rank : 138)
Query Neighborhood Hits	153	Target Neighborhood Hits	770	Shared Neighborhood Hits	57
SwissProt Accessions	P17097, P17015	Gene names	ZNF7, KOX4
Domain Architecture
Description	Zinc finger protein 7 (Zinc finger protein KOX4) (Zinc finger protein HF.16).

RFFL_MOUSE
θ value	0.813845 (rank : 69)	NC score	0.136488 (rank : 53)
Query Neighborhood Hits	153	Target Neighborhood Hits	145	Shared Neighborhood Hits	36
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

UB7I4_MOUSE
θ value	0.813845 (rank : 70)	NC score	0.042664 (rank : 117)
Query Neighborhood Hits	153	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

MAZ_HUMAN
θ value	1.06291 (rank : 71)	NC score	0.035971 (rank : 124)
Query Neighborhood Hits	153	Target Neighborhood Hits	757	Shared Neighborhood Hits	56
SwissProt Accessions	P56270, Q15703, Q99443	Gene names	MAZ
Domain Architecture	No domain graphic available
Description	Myc-associated zinc finger protein (MAZI) (Purine-binding transcription factor) (Pur-1) (ZF87) (ZIF87).

MAZ_MOUSE
θ value	1.06291 (rank : 72)	NC score	0.035893 (rank : 125)
Query Neighborhood Hits	153	Target Neighborhood Hits	745	Shared Neighborhood Hits	55
SwissProt Accessions	P56671, Q9R1W0	Gene names	Maz
Domain Architecture	No domain graphic available
Description	Myc-associated zinc finger protein (MAZI) (Purine-binding transcription factor) (Pur-1).

RFFL_HUMAN
θ value	1.06291 (rank : 73)	NC score	0.129326 (rank : 54)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

SIP1_MOUSE
θ value	1.06291 (rank : 74)	NC score	0.036085 (rank : 123)
Query Neighborhood Hits	153	Target Neighborhood Hits	870	Shared Neighborhood Hits	55
SwissProt Accessions	Q9R0G7	Gene names	Zfhx1b, Sip1, Zfx1b
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1).

ZFP59_MOUSE
θ value	1.06291 (rank : 75)	NC score	0.033684 (rank : 141)
Query Neighborhood Hits	153	Target Neighborhood Hits	768	Shared Neighborhood Hits	57
SwissProt Accessions	P16373, Q61849	Gene names	Zfp59, Mfg2
Domain Architecture	No domain graphic available
Description	Zinc finger protein 59 (Zfp-59) (Zinc finger protein Mfg-2).

ZFP62_HUMAN
θ value	1.06291 (rank : 76)	NC score	0.034752 (rank : 132)
Query Neighborhood Hits	153	Target Neighborhood Hits	768	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NB50	Gene names	ZFP62
Domain Architecture	No domain graphic available
Description	Zinc finger protein 62 homolog (Zfp-62).

ZFP62_MOUSE
θ value	1.06291 (rank : 77)	NC score	0.034857 (rank : 128)
Query Neighborhood Hits	153	Target Neighborhood Hits	786	Shared Neighborhood Hits	61
SwissProt Accessions	Q8C827, Q3U3H0, Q62510, Q8BT00, Q8C2S6, Q8R5D1	Gene names	Zfp62
Domain Architecture	No domain graphic available
Description	Zinc finger protein 62 (Zfp-62) (ZT3).

ZN364_HUMAN
θ value	1.06291 (rank : 78)	NC score	0.038853 (rank : 120)
Query Neighborhood Hits	153	Target Neighborhood Hits	140	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

ZN507_HUMAN
θ value	1.06291 (rank : 79)	NC score	0.042137 (rank : 118)
Query Neighborhood Hits	153	Target Neighborhood Hits	739	Shared Neighborhood Hits	56
SwissProt Accessions	Q8TCN5	Gene names	ZNF507
Domain Architecture	No domain graphic available
Description	Zinc finger protein 507.

GBP5_HUMAN
θ value	1.38821 (rank : 80)	NC score	0.061017 (rank : 78)
Query Neighborhood Hits	153	Target Neighborhood Hits	200	Shared Neighborhood Hits	9
SwissProt Accessions	Q96PP8	Gene names	GBP5
Domain Architecture
Description	Interferon-induced guanylate-binding protein 5 (GTP-binding protein 5) (Guanine nucleotide-binding protein 5) (GBP-5) (GBP-TA antigen).

TRI25_MOUSE
θ value	1.38821 (rank : 81)	NC score	0.046651 (rank : 107)
Query Neighborhood Hits	153	Target Neighborhood Hits	446	Shared Neighborhood Hits	24
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

ZNF28_HUMAN
θ value	1.38821 (rank : 82)	NC score	0.034445 (rank : 133)
Query Neighborhood Hits	153	Target Neighborhood Hits	760	Shared Neighborhood Hits	57
SwissProt Accessions	P17035, Q5HYM9, Q6ZML9, Q6ZN56	Gene names	ZNF28, KOX24
Domain Architecture	No domain graphic available
Description	Zinc finger protein 28 (Zinc finger protein KOX24).

ZNF70_HUMAN
θ value	1.38821 (rank : 83)	NC score	0.033153 (rank : 142)
Query Neighborhood Hits	153	Target Neighborhood Hits	760	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UC06	Gene names	ZNF70
Domain Architecture	No domain graphic available
Description	Zinc finger protein 70 (Zinc finger protein N27C7-1).

FHL3_HUMAN
θ value	1.81305 (rank : 84)	NC score	0.019136 (rank : 177)
Query Neighborhood Hits	153	Target Neighborhood Hits	354	Shared Neighborhood Hits	25
SwissProt Accessions	Q13643	Gene names	FHL3, SLIM2
Domain Architecture
Description	Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM- protein 2) (SLIM 2).

TIF1B_MOUSE
θ value	1.81305 (rank : 85)	NC score	0.043335 (rank : 116)
Query Neighborhood Hits	153	Target Neighborhood Hits	276	Shared Neighborhood Hits	18
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

ZN364_MOUSE
θ value	1.81305 (rank : 86)	NC score	0.034822 (rank : 129)
Query Neighborhood Hits	153	Target Neighborhood Hits	140	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

ZN471_HUMAN
θ value	1.81305 (rank : 87)	NC score	0.032168 (rank : 152)
Query Neighborhood Hits	153	Target Neighborhood Hits	771	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BX82, O75260, Q8N3V1, Q9P2F1	Gene names	ZNF471, ERP1, KIAA1396
Domain Architecture
Description	Zinc finger protein 471 (EZFIT-related protein 1).

CGHB_HUMAN
θ value	2.36792 (rank : 88)	NC score	0.022470 (rank : 175)
Query Neighborhood Hits	153	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	P01233, Q13991, Q14000, Q3SY41, Q8WTT5, Q8WXL2, Q8WXL3, Q8WXL4	Gene names	CGB, CGB3
Domain Architecture
Description	Choriogonadotropin subunit beta precursor (CG-beta) (Chorionic gonadotrophin chain beta).

OVOL2_HUMAN
θ value	2.36792 (rank : 89)	NC score	0.043384 (rank : 115)
Query Neighborhood Hits	153	Target Neighborhood Hits	715	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BRP0, Q5T8B4, Q9BX22, Q9HA54, Q9Y4M0	Gene names	OVOL2, ZNF339
Domain Architecture	No domain graphic available
Description	Transcription factor Ovo-like 2 (hOvo2) (Zinc finger protein 339).

RP3A_MOUSE
θ value	2.36792 (rank : 90)	NC score	0.013202 (rank : 183)
Query Neighborhood Hits	153	Target Neighborhood Hits	510	Shared Neighborhood Hits	13
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

UB7I4_HUMAN
θ value	2.36792 (rank : 91)	NC score	0.028116 (rank : 173)
Query Neighborhood Hits	153	Target Neighborhood Hits	54	Shared Neighborhood Hits	6
SwissProt Accessions	P50876	Gene names	RNF144, KIAA0161, UBCE7IP4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

ZBT17_HUMAN
θ value	2.36792 (rank : 92)	NC score	0.034413 (rank : 134)
Query Neighborhood Hits	153	Target Neighborhood Hits	925	Shared Neighborhood Hits	59
SwissProt Accessions	Q13105, Q15932, Q5JYB2, Q9NUC9	Gene names	ZBTB17, MIZ1, ZNF151
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 17 (Zinc finger protein 151) (Myc-interacting zinc finger protein) (Miz-1 protein).

ZN148_HUMAN
θ value	2.36792 (rank : 93)	NC score	0.033785 (rank : 140)
Query Neighborhood Hits	153	Target Neighborhood Hits	747	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UQR1, O00389, O43591	Gene names	ZNF148, ZBP89
Domain Architecture	No domain graphic available
Description	Zinc finger protein 148 (Zinc finger DNA-binding protein 89) (Transcription factor ZBP-89).

ZN148_MOUSE
θ value	2.36792 (rank : 94)	NC score	0.033787 (rank : 139)
Query Neighborhood Hits	153	Target Neighborhood Hits	755	Shared Neighborhood Hits	54
SwissProt Accessions	Q61624, P97475	Gene names	Znf148, Zbp89, Zfp148
Domain Architecture	No domain graphic available
Description	Zinc finger protein 148 (Zinc finger DNA-binding protein 89) (Transcription factor ZBP-89) (G-rich box-binding protein) (Beta enolase repressor factor 1) (Transcription factor BFCOL1).

ZNF34_HUMAN
θ value	2.36792 (rank : 95)	NC score	0.031341 (rank : 162)
Query Neighborhood Hits	153	Target Neighborhood Hits	760	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IZ26	Gene names	ZNF34, KOX32
Domain Architecture	No domain graphic available
Description	Zinc finger protein 34 (Zinc finger protein KOX32).

MELPH_HUMAN
θ value	3.0926 (rank : 96)	NC score	0.045514 (rank : 108)
Query Neighborhood Hits	153	Target Neighborhood Hits	145	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

MYH6_HUMAN
θ value	3.0926 (rank : 97)	NC score	0.032370 (rank : 149)
Query Neighborhood Hits	153	Target Neighborhood Hits	1426	Shared Neighborhood Hits	21
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

TRI46_MOUSE
θ value	3.0926 (rank : 98)	NC score	0.031485 (rank : 158)
Query Neighborhood Hits	153	Target Neighborhood Hits	287	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

ZN136_HUMAN
θ value	3.0926 (rank : 99)	NC score	0.032137 (rank : 153)
Query Neighborhood Hits	153	Target Neighborhood Hits	739	Shared Neighborhood Hits	59
SwissProt Accessions	P52737	Gene names	ZNF136
Domain Architecture
Description	Zinc finger protein 136.

ZN307_HUMAN
θ value	3.0926 (rank : 100)	NC score	0.031878 (rank : 154)
Query Neighborhood Hits	153	Target Neighborhood Hits	750	Shared Neighborhood Hits	59
SwissProt Accessions	Q969J2	Gene names	ZNF307
Domain Architecture
Description	Zinc finger protein 307 (P373c6.1).

ZN441_HUMAN
θ value	3.0926 (rank : 101)	NC score	0.033096 (rank : 143)
Query Neighborhood Hits	153	Target Neighborhood Hits	754	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N8Z8	Gene names	ZNF441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 441.

ZN678_HUMAN
θ value	3.0926 (rank : 102)	NC score	0.032241 (rank : 151)
Query Neighborhood Hits	153	Target Neighborhood Hits	761	Shared Neighborhood Hits	60
SwissProt Accessions	Q5SXM1, Q8IVQ9	Gene names	ZNF678
Domain Architecture	No domain graphic available
Description	Zinc finger protein 678.

ZNHI3_MOUSE
θ value	3.0926 (rank : 103)	NC score	0.029450 (rank : 171)
Query Neighborhood Hits	153	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CQK1	Gene names	Znhit3, Trip3
Domain Architecture	No domain graphic available
Description	Zinc finger HIT domain-containing protein 3 (Thyroid receptor- interacting protein 3) (TRIP-3) (Thyroid hormone receptor interactor 3).

EPHB6_HUMAN
θ value	4.03905 (rank : 104)	NC score	-0.000006 (rank : 190)
Query Neighborhood Hits	153	Target Neighborhood Hits	912	Shared Neighborhood Hits	6
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

EPHB6_MOUSE
θ value	4.03905 (rank : 105)	NC score	-0.000079 (rank : 191)
Query Neighborhood Hits	153	Target Neighborhood Hits	906	Shared Neighborhood Hits	6
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

EVI1_HUMAN
θ value	4.03905 (rank : 106)	NC score	0.033869 (rank : 137)
Query Neighborhood Hits	153	Target Neighborhood Hits	924	Shared Neighborhood Hits	57
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

EVI1_MOUSE
θ value	4.03905 (rank : 107)	NC score	0.033910 (rank : 136)
Query Neighborhood Hits	153	Target Neighborhood Hits	826	Shared Neighborhood Hits	58
SwissProt Accessions	P14404	Gene names	Evi1, Evi-1
Domain Architecture	No domain graphic available
Description	Ecotropic virus integration 1 site protein.

TIF1B_HUMAN
θ value	4.03905 (rank : 108)	NC score	0.039938 (rank : 119)
Query Neighborhood Hits	153	Target Neighborhood Hits	312	Shared Neighborhood Hits	17
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TRI46_HUMAN
θ value	4.03905 (rank : 109)	NC score	0.028244 (rank : 172)
Query Neighborhood Hits	153	Target Neighborhood Hits	291	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

ZN11B_HUMAN
θ value	4.03905 (rank : 110)	NC score	0.032640 (rank : 148)
Query Neighborhood Hits	153	Target Neighborhood Hits	802	Shared Neighborhood Hits	66
SwissProt Accessions	Q06732, Q86XY8, Q8NDW3	Gene names	ZNF11B
Domain Architecture	No domain graphic available
Description	Zinc finger protein 11B.

ZN182_HUMAN
θ value	4.03905 (rank : 111)	NC score	0.031510 (rank : 157)
Query Neighborhood Hits	153	Target Neighborhood Hits	759	Shared Neighborhood Hits	58
SwissProt Accessions	P17025, Q3KP67	Gene names	ZNF182, KOX14, ZNF21
Domain Architecture	No domain graphic available
Description	Zinc finger protein 182 (Zinc finger protein 21) (Zinc finger protein KOX14).

ZN341_HUMAN
θ value	4.03905 (rank : 112)	NC score	0.034799 (rank : 130)
Query Neighborhood Hits	153	Target Neighborhood Hits	803	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BYN7, Q5JXM8, Q96ST5	Gene names	ZNF341
Domain Architecture	No domain graphic available
Description	Zinc finger protein 341.

ZN433_HUMAN
θ value	4.03905 (rank : 113)	NC score	0.032267 (rank : 150)
Query Neighborhood Hits	153	Target Neighborhood Hits	782	Shared Neighborhood Hits	65
SwissProt Accessions	Q8N7K0	Gene names	ZNF433
Domain Architecture
Description	Zinc finger protein 433.

ZN669_HUMAN
θ value	4.03905 (rank : 114)	NC score	0.031410 (rank : 160)
Query Neighborhood Hits	153	Target Neighborhood Hits	746	Shared Neighborhood Hits	60
SwissProt Accessions	Q96BR6, Q5VT39, Q9H9Q6	Gene names	ZNF669
Domain Architecture	No domain graphic available
Description	Zinc finger protein 669.

ZN672_HUMAN
θ value	4.03905 (rank : 115)	NC score	0.031433 (rank : 159)
Query Neighborhood Hits	153	Target Neighborhood Hits	744	Shared Neighborhood Hits	58
SwissProt Accessions	Q499Z4, Q96H65, Q96IM3, Q9H6G5	Gene names	ZNF672
Domain Architecture	No domain graphic available
Description	Zinc finger protein 672.

C2TA_MOUSE
θ value	5.27518 (rank : 116)	NC score	0.018458 (rank : 178)
Query Neighborhood Hits	153	Target Neighborhood Hits	131	Shared Neighborhood Hits	3
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

EP300_HUMAN
θ value	5.27518 (rank : 117)	NC score	0.015421 (rank : 181)
Query Neighborhood Hits	153	Target Neighborhood Hits	821	Shared Neighborhood Hits	13
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

GBP2_HUMAN
θ value	5.27518 (rank : 118)	NC score	0.055594 (rank : 86)
Query Neighborhood Hits	153	Target Neighborhood Hits	349	Shared Neighborhood Hits	17
SwissProt Accessions	P32456, Q86TB0	Gene names	GBP2
Domain Architecture
Description	Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (Guanine nucleotide-binding protein 2) (GBP-2) (HuGBP-2).

INADL_HUMAN
θ value	5.27518 (rank : 119)	NC score	0.007532 (rank : 189)
Query Neighborhood Hits	153	Target Neighborhood Hits	260	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

MYH6_MOUSE
θ value	5.27518 (rank : 120)	NC score	0.031635 (rank : 155)
Query Neighborhood Hits	153	Target Neighborhood Hits	1501	Shared Neighborhood Hits	20
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH7_HUMAN
θ value	5.27518 (rank : 121)	NC score	0.031395 (rank : 161)
Query Neighborhood Hits	153	Target Neighborhood Hits	1559	Shared Neighborhood Hits	21
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

RNF17_MOUSE
θ value	5.27518 (rank : 122)	NC score	0.056071 (rank : 84)
Query Neighborhood Hits	153	Target Neighborhood Hits	147	Shared Neighborhood Hits	18
SwissProt Accessions	Q99MV7	Gene names	Rnf17
Domain Architecture
Description	RING finger protein 17.

RNF34_HUMAN
θ value	5.27518 (rank : 123)	NC score	0.123927 (rank : 56)
Query Neighborhood Hits	153	Target Neighborhood Hits	153	Shared Neighborhood Hits	33
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

ZBT17_MOUSE
θ value	5.27518 (rank : 124)	NC score	0.032867 (rank : 145)
Query Neighborhood Hits	153	Target Neighborhood Hits	940	Shared Neighborhood Hits	57
SwissProt Accessions	Q60821, Q60699	Gene names	Zbtb17, Zfp100, Znf151
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 17 (Zinc finger protein 151) (Zinc finger protein 100) (Zfp-100) (Polyomavirus late initiator promoter-binding protein) (LP-1) (Zinc finger protein Z13).

ZN449_HUMAN
θ value	5.27518 (rank : 125)	NC score	0.032798 (rank : 146)
Query Neighborhood Hits	153	Target Neighborhood Hits	758	Shared Neighborhood Hits	59
SwissProt Accessions	Q6P9G9, Q5JRZ8, Q6NZX2, Q8N3Q1, Q8TED7	Gene names	ZNF449, ZSCAN19
Domain Architecture	No domain graphic available
Description	Zinc finger protein 449 (Zinc finger and SCAN domain-containing protein 19).

ARD1_HUMAN
θ value	6.88961 (rank : 126)	NC score	0.013689 (rank : 182)
Query Neighborhood Hits	153	Target Neighborhood Hits	621	Shared Neighborhood Hits	39
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

CBP_HUMAN
θ value	6.88961 (rank : 127)	NC score	0.017900 (rank : 179)
Query Neighborhood Hits	153	Target Neighborhood Hits	941	Shared Neighborhood Hits	17
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

ERC2_HUMAN
θ value	6.88961 (rank : 128)	NC score	0.044172 (rank : 112)
Query Neighborhood Hits	153	Target Neighborhood Hits	1156	Shared Neighborhood Hits	23
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ERC2_MOUSE
θ value	6.88961 (rank : 129)	NC score	0.044165 (rank : 113)
Query Neighborhood Hits	153	Target Neighborhood Hits	1166	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

FGD3_MOUSE
θ value	6.88961 (rank : 130)	NC score	0.259935 (rank : 44)
Query Neighborhood Hits	153	Target Neighborhood Hits	257	Shared Neighborhood Hits	62
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

FRAS1_HUMAN
θ value	6.88961 (rank : 131)	NC score	0.009735 (rank : 187)
Query Neighborhood Hits	153	Target Neighborhood Hits	759	Shared Neighborhood Hits	31
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

IF2P_HUMAN
θ value	6.88961 (rank : 132)	NC score	0.020635 (rank : 176)
Query Neighborhood Hits	153	Target Neighborhood Hits	889	Shared Neighborhood Hits	17
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

MEGF8_HUMAN
θ value	6.88961 (rank : 133)	NC score	0.007886 (rank : 188)
Query Neighborhood Hits	153	Target Neighborhood Hits	528	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MYLK_HUMAN
θ value	6.88961 (rank : 134)	NC score	-0.005394 (rank : 192)
Query Neighborhood Hits	153	Target Neighborhood Hits	1328	Shared Neighborhood Hits	4
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

RAD21_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.031209 (rank : 163)
Query Neighborhood Hits	153	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	O60216, Q15001, Q99568	Gene names	RAD21, HR21, KIAA0078, NXP1
Domain Architecture
Description	Double-strand-break repair protein rad21 homolog (hHR21) (Nuclear matrix protein 1) (NXP-1) (SCC1 homolog).

RAD21_MOUSE
θ value	6.88961 (rank : 136)	NC score	0.031020 (rank : 165)
Query Neighborhood Hits	153	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q61550, P70219, Q91VB9, Q9DBU4	Gene names	Rad21, Hr21
Domain Architecture
Description	Double-strand-break repair protein rad21 homolog (Pokeweed agglutinin- binding protein 29) (PW29) (SCC1 homolog).

RNF34_MOUSE
θ value	6.88961 (rank : 137)	NC score	0.128266 (rank : 55)
Query Neighborhood Hits	153	Target Neighborhood Hits	160	Shared Neighborhood Hits	37
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

STP2_MOUSE
θ value	6.88961 (rank : 138)	NC score	0.037695 (rank : 122)
Query Neighborhood Hits	153	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	P11378	Gene names	Tnp2
Domain Architecture	No domain graphic available
Description	Nuclear transition protein 2 (TP-2) (TP2).

ZN224_HUMAN
θ value	6.88961 (rank : 139)	NC score	0.030992 (rank : 166)
Query Neighborhood Hits	153	Target Neighborhood Hits	808	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NZL3, Q86V10, Q8IZC8, Q9UID9, Q9Y2P6	Gene names	ZNF224, BMZF2, ZNF255
Domain Architecture
Description	Zinc finger protein 224 (Zinc finger protein 255) (Bone marrow zinc finger 2) (BMZF-2).

ZN236_HUMAN
θ value	6.88961 (rank : 140)	NC score	0.032956 (rank : 144)
Query Neighborhood Hits	153	Target Neighborhood Hits	844	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UL36, Q9UL37	Gene names	ZNF236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 236.

ZN346_HUMAN
θ value	6.88961 (rank : 141)	NC score	0.023484 (rank : 174)
Query Neighborhood Hits	153	Target Neighborhood Hits	64	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UL40, Q68CV9, Q6ZMW1	Gene names	ZNF346, JAZ
Domain Architecture	No domain graphic available
Description	Zinc finger protein 346 (Just another zinc finger protein).

ZN542_HUMAN
θ value	6.88961 (rank : 142)	NC score	0.030890 (rank : 167)
Query Neighborhood Hits	153	Target Neighborhood Hits	735	Shared Neighborhood Hits	59
SwissProt Accessions	Q5EBM4, Q6N061	Gene names	ZNF542
Domain Architecture	No domain graphic available
Description	Zinc finger protein 542.

ZN677_HUMAN
θ value	6.88961 (rank : 143)	NC score	0.031190 (rank : 164)
Query Neighborhood Hits	153	Target Neighborhood Hits	761	Shared Neighborhood Hits	59
SwissProt Accessions	Q86XU0	Gene names	ZNF677
Domain Architecture	No domain graphic available
Description	Zinc finger protein 677.

ATBF1_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.030842 (rank : 168)
Query Neighborhood Hits	153	Target Neighborhood Hits	1547	Shared Neighborhood Hits	62
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

ATBF1_MOUSE
θ value	8.99809 (rank : 145)	NC score	0.033996 (rank : 135)
Query Neighborhood Hits	153	Target Neighborhood Hits	1841	Shared Neighborhood Hits	66
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

DNMT2_HUMAN
θ value	8.99809 (rank : 146)	NC score	0.011772 (rank : 186)
Query Neighborhood Hits	153	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	O14717, O43669	Gene names	DNMT2
Domain Architecture
Description	tRNA (cytosine-5-)-methyltransferase (EC 2.1.1.29) (DNA (cytosine-5)- methyltransferase-like protein 2) (Dnmt2) (DNA methyltransferase homolog HsaIIP) (DNA MTase homolog HsaIIP) (M.HsaIIP) (PuMet).

FHL1_MOUSE
θ value	8.99809 (rank : 147)	NC score	0.016019 (rank : 180)
Query Neighborhood Hits	153	Target Neighborhood Hits	462	Shared Neighborhood Hits	34
SwissProt Accessions	P97447, O55181, Q8K318	Gene names	Fhl1
Domain Architecture
Description	Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM- protein 1) (SLIM 1) (SLIM) (KyoT) (RBP-associated molecule 14-1) (RAM14-1).

MLL3_HUMAN
θ value	8.99809 (rank : 148)	NC score	0.011972 (rank : 185)
Query Neighborhood Hits	153	Target Neighborhood Hits	1644	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

TAF1_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.012065 (rank : 184)
Query Neighborhood Hits	153	Target Neighborhood Hits	136	Shared Neighborhood Hits	6
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

ZN248_HUMAN
θ value	8.99809 (rank : 150)	NC score	0.029748 (rank : 170)
Query Neighborhood Hits	153	Target Neighborhood Hits	749	Shared Neighborhood Hits	59
SwissProt Accessions	Q8NDW4, Q9UMP3	Gene names	ZNF248
Domain Architecture
Description	Zinc finger protein 248.

ZN250_HUMAN
θ value	8.99809 (rank : 151)	NC score	0.030397 (rank : 169)
Query Neighborhood Hits	153	Target Neighborhood Hits	756	Shared Neighborhood Hits	58
SwissProt Accessions	P15622, Q8N942, Q96AH9	Gene names	ZNF250, ZNF647
Domain Architecture	No domain graphic available
Description	Zinc finger protein 250 (Zinc finger protein 647).

ZN408_HUMAN
θ value	8.99809 (rank : 152)	NC score	0.031527 (rank : 156)
Query Neighborhood Hits	153	Target Neighborhood Hits	775	Shared Neighborhood Hits	58
SwissProt Accessions	Q9H9D4	Gene names	ZNF408, PFM14, PRDM17
Domain Architecture	No domain graphic available
Description	Zinc finger protein 408 (PR-domain zinc finger protein 17).

ZNF91_HUMAN
θ value	8.99809 (rank : 153)	NC score	0.032763 (rank : 147)
Query Neighborhood Hits	153	Target Neighborhood Hits	797	Shared Neighborhood Hits	60
SwissProt Accessions	Q05481	Gene names	ZNF91
Domain Architecture
Description	Zinc finger protein 91 (Zinc finger protein HTF10) (HPF7).

ABR_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.051113 (rank : 99)
Query Neighborhood Hits	153	Target Neighborhood Hits	166	Shared Neighborhood Hits	13
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

ARHG1_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.050877 (rank : 100)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	13
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

ARHG2_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.057121 (rank : 81)
Query Neighborhood Hits	153	Target Neighborhood Hits	120	Shared Neighborhood Hits	13
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

ARHG4_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.051175 (rank : 98)
Query Neighborhood Hits	153	Target Neighborhood Hits	242	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG4_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.050762 (rank : 101)
Query Neighborhood Hits	153	Target Neighborhood Hits	185	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG5_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.071071 (rank : 68)
Query Neighborhood Hits	153	Target Neighborhood Hits	172	Shared Neighborhood Hits	12
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

ARHGA_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.067821 (rank : 71)
Query Neighborhood Hits	153	Target Neighborhood Hits	187	Shared Neighborhood Hits	16
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGA_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.068397 (rank : 70)
Query Neighborhood Hits	153	Target Neighborhood Hits	125	Shared Neighborhood Hits	13
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGF_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.066653 (rank : 72)
Query Neighborhood Hits	153	Target Neighborhood Hits	214	Shared Neighborhood Hits	13
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ARHGG_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.061730 (rank : 77)
Query Neighborhood Hits	153	Target Neighborhood Hits	129	Shared Neighborhood Hits	12
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ARHGG_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.056988 (rank : 82)
Query Neighborhood Hits	153	Target Neighborhood Hits	152	Shared Neighborhood Hits	12
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

BCR_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.051914 (rank : 95)
Query Neighborhood Hits	153	Target Neighborhood Hits	204	Shared Neighborhood Hits	12
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

CARD9_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.052061 (rank : 93)
Query Neighborhood Hits	153	Target Neighborhood Hits	602	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

CCDC6_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.054577 (rank : 88)
Query Neighborhood Hits	153	Target Neighborhood Hits	723	Shared Neighborhood Hits	20
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

CJ064_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.085139 (rank : 61)
Query Neighborhood Hits	153	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZS81, Q8N4A3	Gene names	C10orf64
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf64.

ECT2_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.080009 (rank : 64)
Query Neighborhood Hits	153	Target Neighborhood Hits	98	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ECT2_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.082071 (rank : 63)
Query Neighborhood Hits	153	Target Neighborhood Hits	98	Shared Neighborhood Hits	12
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

FARP1_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.090180 (rank : 60)
Query Neighborhood Hits	153	Target Neighborhood Hits	241	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FARP2_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.093580 (rank : 57)
Query Neighborhood Hits	153	Target Neighborhood Hits	240	Shared Neighborhood Hits	18
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.092131 (rank : 58)
Query Neighborhood Hits	153	Target Neighborhood Hits	209	Shared Neighborhood Hits	16
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

GNRP_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.053255 (rank : 89)
Query Neighborhood Hits	153	Target Neighborhood Hits	239	Shared Neighborhood Hits	19
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

GNRP_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.052236 (rank : 92)
Query Neighborhood Hits	153	Target Neighborhood Hits	191	Shared Neighborhood Hits	16
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

HAPIP_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.074830 (rank : 66)
Query Neighborhood Hits	153	Target Neighborhood Hits	350	Shared Neighborhood Hits	24
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

ITSN1_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.051788 (rank : 97)
Query Neighborhood Hits	153	Target Neighborhood Hits	1757	Shared Neighborhood Hits	34
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.051937 (rank : 94)
Query Neighborhood Hits	153	Target Neighborhood Hits	1669	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN2_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.050736 (rank : 102)
Query Neighborhood Hits	153	Target Neighborhood Hits	1371	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

LBC_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.053019 (rank : 90)
Query Neighborhood Hits	153	Target Neighborhood Hits	90	Shared Neighborhood Hits	14
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

MCF2L_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.059882 (rank : 79)
Query Neighborhood Hits	153	Target Neighborhood Hits	255	Shared Neighborhood Hits	15
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

MCF2_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.056430 (rank : 83)
Query Neighborhood Hits	153	Target Neighborhood Hits	166	Shared Neighborhood Hits	13
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

NBEAL_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.050710 (rank : 103)
Query Neighborhood Hits	153	Target Neighborhood Hits	200	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZS30, Q6Y876, Q6ZQY5, Q96Q30	Gene names	NBEAL1, ALS2CR17
Domain Architecture	No domain graphic available
Description	Neurobeachin-like 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein).

NGEF_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.061861 (rank : 76)
Query Neighborhood Hits	153	Target Neighborhood Hits	166	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

NGEF_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.059864 (rank : 80)
Query Neighborhood Hits	153	Target Neighborhood Hits	228	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

PKHG1_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.068752 (rank : 69)
Query Neighborhood Hits	153	Target Neighborhood Hits	174	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

PKHG4_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.055550 (rank : 87)
Query Neighborhood Hits	153	Target Neighborhood Hits	200	Shared Neighborhood Hits	12
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

PREX1_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.092047 (rank : 59)
Query Neighborhood Hits	153	Target Neighborhood Hits	177	Shared Neighborhood Hits	19
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

RUFY3_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.147361 (rank : 52)
Query Neighborhood Hits	153	Target Neighborhood Hits	594	Shared Neighborhood Hits	15
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

RUFY3_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.148515 (rank : 51)
Query Neighborhood Hits	153	Target Neighborhood Hits	579	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

SWP70_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.052943 (rank : 91)
Query Neighborhood Hits	153	Target Neighborhood Hits	973	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.050709 (rank : 104)
Query Neighborhood Hits	153	Target Neighborhood Hits	1097	Shared Neighborhood Hits	36
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

Hits sorted by NC score

ZFYV1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	153	Target Neighborhood Hits	153	Shared Neighborhood Hits	153
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

ZFYV1_HUMAN
NC score	0.991138 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	153	Target Neighborhood Hits	166	Shared Neighborhood Hits	117
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

ZFY28_HUMAN
NC score	0.647917 (rank : 3)	θ value	1.47974e-10 (rank : 8)
Query Neighborhood Hits	153	Target Neighborhood Hits	152	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

ZFY21_HUMAN
NC score	0.640384 (rank : 4)	θ value	1.17247e-07 (rank : 16)
Query Neighborhood Hits	153	Target Neighborhood Hits	72	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BQ24, Q86T05, Q96LT1	Gene names	ZFYVE21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY21_MOUSE
NC score	0.639765 (rank : 5)	θ value	1.53129e-07 (rank : 19)
Query Neighborhood Hits	153	Target Neighborhood Hits	72	Shared Neighborhood Hits	59
SwissProt Accessions	Q8VCM3, Q9D1E2	Gene names	Zfyve21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

PKHF2_MOUSE
NC score	0.577852 (rank : 6)	θ value	1.99992e-07 (rank : 21)
Query Neighborhood Hits	153	Target Neighborhood Hits	77	Shared Neighborhood Hits	48
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

PKHF2_HUMAN
NC score	0.577077 (rank : 7)	θ value	1.99992e-07 (rank : 20)
Query Neighborhood Hits	153	Target Neighborhood Hits	75	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

PKHF1_HUMAN
NC score	0.567035 (rank : 8)	θ value	2.88788e-06 (rank : 28)
Query Neighborhood Hits	153	Target Neighborhood Hits	76	Shared Neighborhood Hits	51
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

PKHF1_MOUSE
NC score	0.554732 (rank : 9)	θ value	4.1701e-05 (rank : 37)
Query Neighborhood Hits	153	Target Neighborhood Hits	80	Shared Neighborhood Hits	51
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

ZFY16_MOUSE
NC score	0.541200 (rank : 10)	θ value	3.41135e-07 (rank : 23)
Query Neighborhood Hits	153	Target Neighborhood Hits	108	Shared Neighborhood Hits	59
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

ZFYV9_HUMAN
NC score	0.537297 (rank : 11)	θ value	4.92598e-06 (rank : 32)
Query Neighborhood Hits	153	Target Neighborhood Hits	134	Shared Neighborhood Hits	54
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

ZFY16_HUMAN
NC score	0.536831 (rank : 12)	θ value	8.97725e-08 (rank : 15)
Query Neighborhood Hits	153	Target Neighborhood Hits	125	Shared Neighborhood Hits	58
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

HGS_HUMAN
NC score	0.508096 (rank : 13)	θ value	1.47974e-10 (rank : 6)
Query Neighborhood Hits	153	Target Neighborhood Hits	517	Shared Neighborhood Hits	60
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HGS_MOUSE
NC score	0.505142 (rank : 14)	θ value	1.47974e-10 (rank : 7)
Query Neighborhood Hits	153	Target Neighborhood Hits	589	Shared Neighborhood Hits	61
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

FYV1_MOUSE
NC score	0.476796 (rank : 15)	θ value	6.21693e-09 (rank : 14)
Query Neighborhood Hits	153	Target Neighborhood Hits	191	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

FYV1_HUMAN
NC score	0.476448 (rank : 16)	θ value	6.21693e-09 (rank : 13)
Query Neighborhood Hits	153	Target Neighborhood Hits	217	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

RBNS5_HUMAN
NC score	0.432498 (rank : 17)	θ value	0.000121331 (rank : 39)
Query Neighborhood Hits	153	Target Neighborhood Hits	242	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

RBNS5_MOUSE
NC score	0.428429 (rank : 18)	θ value	0.000121331 (rank : 40)
Query Neighborhood Hits	153	Target Neighborhood Hits	266	Shared Neighborhood Hits	54
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

FGD6_HUMAN
NC score	0.418184 (rank : 19)	θ value	2.21117e-06 (rank : 27)
Query Neighborhood Hits	153	Target Neighborhood Hits	237	Shared Neighborhood Hits	51
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD5_HUMAN
NC score	0.415563 (rank : 20)	θ value	3.77169e-06 (rank : 30)
Query Neighborhood Hits	153	Target Neighborhood Hits	235	Shared Neighborhood Hits	55
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

FGD5_MOUSE
NC score	0.406857 (rank : 21)	θ value	0.00134147 (rank : 42)
Query Neighborhood Hits	153	Target Neighborhood Hits	170	Shared Neighborhood Hits	54
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

FGD6_MOUSE
NC score	0.403721 (rank : 22)	θ value	1.43324e-05 (rank : 36)
Query Neighborhood Hits	153	Target Neighborhood Hits	282	Shared Neighborhood Hits	51
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

ZFY19_HUMAN
NC score	0.396397 (rank : 23)	θ value	0.0252991 (rank : 47)
Query Neighborhood Hits	153	Target Neighborhood Hits	206	Shared Neighborhood Hits	60
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

RUFY1_MOUSE
NC score	0.389084 (rank : 24)	θ value	7.84624e-12 (rank : 4)
Query Neighborhood Hits	153	Target Neighborhood Hits	765	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

ZFY19_MOUSE
NC score	0.388244 (rank : 25)	θ value	0.0736092 (rank : 54)
Query Neighborhood Hits	153	Target Neighborhood Hits	143	Shared Neighborhood Hits	56
SwissProt Accessions	Q9DAZ9, Q8VCV7	Gene names	Zfyve19
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19.

WDFY1_HUMAN
NC score	0.386249 (rank : 26)	θ value	3.41135e-07 (rank : 22)
Query Neighborhood Hits	153	Target Neighborhood Hits	305	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IWB7, Q9H9D5, Q9P2B3	Gene names	WDFY1, KIAA1435, WDF1, ZFYVE17
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 1 (WD40- and FYVE domain- containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain-containing protein 17).

RUFY1_HUMAN
NC score	0.384264 (rank : 27)	θ value	2.0648e-12 (rank : 3)
Query Neighborhood Hits	153	Target Neighborhood Hits	848	Shared Neighborhood Hits	67
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

RUFY2_MOUSE
NC score	0.378516 (rank : 28)	θ value	1.9326e-10 (rank : 9)
Query Neighborhood Hits	153	Target Neighborhood Hits	820	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

WDFY2_MOUSE
NC score	0.378200 (rank : 29)	θ value	1.69304e-06 (rank : 26)
Query Neighborhood Hits	153	Target Neighborhood Hits	337	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BUB4	Gene names	Wdfy2
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2).

WDFY2_HUMAN
NC score	0.376138 (rank : 30)	θ value	1.29631e-06 (rank : 25)
Query Neighborhood Hits	153	Target Neighborhood Hits	332	Shared Neighborhood Hits	50
SwissProt Accessions	Q96P53, Q96CS1	Gene names	WDFY2, WDF2, ZFYVE22
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2) (Zinc finger FYVE domain-containing protein 22).

MTMR3_HUMAN
NC score	0.375909 (rank : 31)	θ value	7.34386e-10 (rank : 10)
Query Neighborhood Hits	153	Target Neighborhood Hits	163	Shared Neighborhood Hits	55
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

FGD2_MOUSE
NC score	0.375532 (rank : 32)	θ value	1.09739e-05 (rank : 34)
Query Neighborhood Hits	153	Target Neighborhood Hits	163	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

FGD2_HUMAN
NC score	0.374588 (rank : 33)	θ value	1.43324e-05 (rank : 35)
Query Neighborhood Hits	153	Target Neighborhood Hits	151	Shared Neighborhood Hits	51
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

WDFY3_MOUSE
NC score	0.352386 (rank : 34)	θ value	1.53129e-07 (rank : 18)
Query Neighborhood Hits	153	Target Neighborhood Hits	332	Shared Neighborhood Hits	56
SwissProt Accessions	Q6VNB8, Q8C8H7	Gene names	Wdfy3
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1).

WDFY3_HUMAN
NC score	0.351132 (rank : 35)	θ value	1.53129e-07 (rank : 17)
Query Neighborhood Hits	153	Target Neighborhood Hits	348	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

FGD4_MOUSE
NC score	0.350389 (rank : 36)	θ value	5.44631e-05 (rank : 38)
Query Neighborhood Hits	153	Target Neighborhood Hits	227	Shared Neighborhood Hits	52
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGD4_HUMAN
NC score	0.348820 (rank : 37)	θ value	0.00035302 (rank : 41)
Query Neighborhood Hits	153	Target Neighborhood Hits	219	Shared Neighborhood Hits	51
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

ZFY27_HUMAN
NC score	0.335382 (rank : 38)	θ value	0.0563607 (rank : 52)
Query Neighborhood Hits	153	Target Neighborhood Hits	64	Shared Neighborhood Hits	46
SwissProt Accessions	Q5T4F4, Q5T4F1, Q5T4F2, Q5T4F3, Q8N1K0, Q8N6D6, Q8NCA0, Q8NDE4, Q96M08	Gene names	ZFYVE27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

ZFY27_MOUSE
NC score	0.335015 (rank : 39)	θ value	0.0563607 (rank : 53)
Query Neighborhood Hits	153	Target Neighborhood Hits	53	Shared Neighborhood Hits	44
SwissProt Accessions	Q3TXX3, Q8CFP8	Gene names	Zfyve27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

FGD1_HUMAN
NC score	0.328665 (rank : 40)	θ value	0.00665767 (rank : 44)
Query Neighborhood Hits	153	Target Neighborhood Hits	367	Shared Neighborhood Hits	54
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_MOUSE
NC score	0.327297 (rank : 41)	θ value	0.00665767 (rank : 45)
Query Neighborhood Hits	153	Target Neighborhood Hits	387	Shared Neighborhood Hits	53
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD3_HUMAN
NC score	0.307665 (rank : 42)	θ value	0.0563607 (rank : 51)
Query Neighborhood Hits	153	Target Neighborhood Hits	249	Shared Neighborhood Hits	60
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

RUFY2_HUMAN
NC score	0.302401 (rank : 43)	θ value	1.133e-10 (rank : 5)
Query Neighborhood Hits	153	Target Neighborhood Hits	1208	Shared Neighborhood Hits	69
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

FGD3_MOUSE
NC score	0.259935 (rank : 44)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	153	Target Neighborhood Hits	257	Shared Neighborhood Hits	62
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

FYCO1_HUMAN
NC score	0.243297 (rank : 45)	θ value	3.77169e-06 (rank : 31)
Query Neighborhood Hits	153	Target Neighborhood Hits	1149	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

ANFY1_MOUSE
NC score	0.236814 (rank : 46)	θ value	3.77169e-06 (rank : 29)
Query Neighborhood Hits	153	Target Neighborhood Hits	480	Shared Neighborhood Hits	56
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANFY1_HUMAN
NC score	0.235144 (rank : 47)	θ value	6.43352e-06 (rank : 33)
Query Neighborhood Hits	153	Target Neighborhood Hits	480	Shared Neighborhood Hits	54
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

FYCO1_MOUSE
NC score	0.233854 (rank : 48)	θ value	9.92553e-07 (rank : 24)
Query Neighborhood Hits	153	Target Neighborhood Hits	1059	Shared Neighborhood Hits	61
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

EEA1_MOUSE
NC score	0.220745 (rank : 49)	θ value	3.64472e-09 (rank : 11)
Query Neighborhood Hits	153	Target Neighborhood Hits	1637	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

EEA1_HUMAN
NC score	0.204111 (rank : 50)	θ value	4.76016e-09 (rank : 12)
Query Neighborhood Hits	153	Target Neighborhood Hits	1796	Shared Neighborhood Hits	79
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

RUFY3_MOUSE
NC score	0.148515 (rank : 51)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	153	Target Neighborhood Hits	579	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

RUFY3_HUMAN
NC score	0.147361 (rank : 52)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	153	Target Neighborhood Hits	594	Shared Neighborhood Hits	15
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

RFFL_MOUSE
NC score	0.136488 (rank : 53)	θ value	0.813845 (rank : 69)
Query Neighborhood Hits	153	Target Neighborhood Hits	145	Shared Neighborhood Hits	36
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RFFL_HUMAN
NC score	0.129326 (rank : 54)	θ value	1.06291 (rank : 73)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RNF34_MOUSE
NC score	0.128266 (rank : 55)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	153	Target Neighborhood Hits	160	Shared Neighborhood Hits	37
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RNF34_HUMAN
NC score	0.123927 (rank : 56)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	153	Target Neighborhood Hits	153	Shared Neighborhood Hits	33
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

FARP2_HUMAN
NC score	0.093580 (rank : 57)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	153	Target Neighborhood Hits	240	Shared Neighborhood Hits	18
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_MOUSE
NC score	0.092131 (rank : 58)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	153	Target Neighborhood Hits	209	Shared Neighborhood Hits	16
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

PREX1_HUMAN
NC score	0.092047 (rank : 59)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	153	Target Neighborhood Hits	177	Shared Neighborhood Hits	19
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

FARP1_HUMAN
NC score	0.090180 (rank : 60)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	153	Target Neighborhood Hits	241	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

CJ064_HUMAN
NC score	0.085139 (rank : 61)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	153	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZS81, Q8N4A3	Gene names	C10orf64
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf64.

ZFAN1_HUMAN
NC score	0.082802 (rank : 62)	θ value	0.0148317 (rank : 46)
Query Neighborhood Hits	153	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TCF1, Q658R7, Q6IA32, Q6PGQ6, Q9H810	Gene names	ZFAND1
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 1.

ECT2_MOUSE
NC score	0.082071 (rank : 63)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	153	Target Neighborhood Hits	98	Shared Neighborhood Hits	12
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ECT2_HUMAN
NC score	0.080009 (rank : 64)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	153	Target Neighborhood Hits	98	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

GBP4_HUMAN
NC score	0.078057 (rank : 65)	θ value	0.0431538 (rank : 48)
Query Neighborhood Hits	153	Target Neighborhood Hits	484	Shared Neighborhood Hits	18
SwissProt Accessions	Q96PP9, Q86T99	Gene names	GBP4
Domain Architecture
Description	Guanylate-binding protein 4 (GTP-binding protein 4) (Guanine nucleotide-binding protein 4) (GBP-4).

HAPIP_HUMAN
NC score	0.074830 (rank : 66)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	153	Target Neighborhood Hits	350	Shared Neighborhood Hits	24
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

TRI42_MOUSE
NC score	0.074115 (rank : 67)	θ value	0.0961366 (rank : 56)
Query Neighborhood Hits	153	Target Neighborhood Hits	316	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

ARHG5_HUMAN
NC score	0.071071 (rank : 68)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	153	Target Neighborhood Hits	172	Shared Neighborhood Hits	12
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

PKHG1_HUMAN
NC score	0.068752 (rank : 69)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	153	Target Neighborhood Hits	174	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

ARHGA_MOUSE
NC score	0.068397 (rank : 70)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	153	Target Neighborhood Hits	125	Shared Neighborhood Hits	13
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGA_HUMAN
NC score	0.067821 (rank : 71)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	153	Target Neighborhood Hits	187	Shared Neighborhood Hits	16
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGF_HUMAN
NC score	0.066653 (rank : 72)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	153	Target Neighborhood Hits	214	Shared Neighborhood Hits	13
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

TRI25_HUMAN
NC score	0.066239 (rank : 73)	θ value	0.00509761 (rank : 43)
Query Neighborhood Hits	153	Target Neighborhood Hits	472	Shared Neighborhood Hits	18
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

GBP5_MOUSE
NC score	0.065689 (rank : 74)	θ value	0.365318 (rank : 61)
Query Neighborhood Hits	153	Target Neighborhood Hits	254	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CFB4, Q8CFA4	Gene names	Gbp5
Domain Architecture
Description	Interferon-induced guanylate-binding protein 5 (GTP-binding protein 5) (Guanine nucleotide-binding protein 5) (GBP-5) (MuGBP-5).

TRI42_HUMAN
NC score	0.065310 (rank : 75)	θ value	0.62314 (rank : 66)
Query Neighborhood Hits	153	Target Neighborhood Hits	283	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

NGEF_HUMAN
NC score	0.061861 (rank : 76)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	153	Target Neighborhood Hits	166	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

ARHGG_HUMAN
NC score	0.061730 (rank : 77)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	153	Target Neighborhood Hits	129	Shared Neighborhood Hits	12
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

GBP5_HUMAN
NC score	0.061017 (rank : 78)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	153	Target Neighborhood Hits	200	Shared Neighborhood Hits	9
SwissProt Accessions	Q96PP8	Gene names	GBP5
Domain Architecture
Description	Interferon-induced guanylate-binding protein 5 (GTP-binding protein 5) (Guanine nucleotide-binding protein 5) (GBP-5) (GBP-TA antigen).

MCF2L_MOUSE
NC score	0.059882 (rank : 79)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	153	Target Neighborhood Hits	255	Shared Neighborhood Hits	15
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

NGEF_MOUSE
NC score	0.059864 (rank : 80)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	153	Target Neighborhood Hits	228	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

ARHG2_MOUSE
NC score	0.057121 (rank : 81)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	153	Target Neighborhood Hits	120	Shared Neighborhood Hits	13
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

ARHGG_MOUSE
NC score	0.056988 (rank : 82)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	153	Target Neighborhood Hits	152	Shared Neighborhood Hits	12
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

MCF2_HUMAN
NC score	0.056430 (rank : 83)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	153	Target Neighborhood Hits	166	Shared Neighborhood Hits	13
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

RNF17_MOUSE
NC score	0.056071 (rank : 84)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	153	Target Neighborhood Hits	147	Shared Neighborhood Hits	18
SwissProt Accessions	Q99MV7	Gene names	Rnf17
Domain Architecture
Description	RING finger protein 17.

ZN295_HUMAN
NC score	0.056004 (rank : 85)	θ value	0.0431538 (rank : 50)
Query Neighborhood Hits	153	Target Neighborhood Hits	847	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ULJ3, Q6P4R0	Gene names	ZNF295, KIAA1227, ZBTB21
Domain Architecture
Description	Zinc finger protein 295 (Zinc finger and BTB domain-containing protein 21).

GBP2_HUMAN
NC score	0.055594 (rank : 86)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	153	Target Neighborhood Hits	349	Shared Neighborhood Hits	17
SwissProt Accessions	P32456, Q86TB0	Gene names	GBP2
Domain Architecture
Description	Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (Guanine nucleotide-binding protein 2) (GBP-2) (HuGBP-2).

PKHG4_HUMAN
NC score	0.055550 (rank : 87)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	153	Target Neighborhood Hits	200	Shared Neighborhood Hits	12
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

CCDC6_HUMAN
NC score	0.054577 (rank : 88)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	153	Target Neighborhood Hits	723	Shared Neighborhood Hits	20
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

GNRP_HUMAN
NC score	0.053255 (rank : 89)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	153	Target Neighborhood Hits	239	Shared Neighborhood Hits	19
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

LBC_HUMAN
NC score	0.053019 (rank : 90)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	153	Target Neighborhood Hits	90	Shared Neighborhood Hits	14
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

SWP70_HUMAN
NC score	0.052943 (rank : 91)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	153	Target Neighborhood Hits	973	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

GNRP_MOUSE
NC score	0.052236 (rank : 92)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	153	Target Neighborhood Hits	191	Shared Neighborhood Hits	16
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

CARD9_HUMAN
NC score	0.052061 (rank : 93)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	153	Target Neighborhood Hits	602	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

ITSN1_MOUSE
NC score	0.051937 (rank : 94)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	153	Target Neighborhood Hits	1669	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

BCR_HUMAN
NC score	0.051914 (rank : 95)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	153	Target Neighborhood Hits	204	Shared Neighborhood Hits	12
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

OVOL1_MOUSE
NC score	0.051872 (rank : 96)	θ value	0.0431538 (rank : 49)
Query Neighborhood Hits	153	Target Neighborhood Hits	716	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WTJ2, Q545S2	Gene names	Ovol1
Domain Architecture	No domain graphic available
Description	Putative transcription factor Ovo-like 1 (mOvo1) (mOvo1a).

ITSN1_HUMAN
NC score	0.051788 (rank : 97)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	153	Target Neighborhood Hits	1757	Shared Neighborhood Hits	34
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ARHG4_HUMAN
NC score	0.051175 (rank : 98)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	153	Target Neighborhood Hits	242	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ABR_HUMAN
NC score	0.051113 (rank : 99)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	153	Target Neighborhood Hits	166	Shared Neighborhood Hits	13
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

ARHG1_HUMAN
NC score	0.050877 (rank : 100)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	13
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

ARHG4_MOUSE
NC score	0.050762 (rank : 101)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	153	Target Neighborhood Hits	185	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ITSN2_MOUSE
NC score	0.050736 (rank : 102)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	153	Target Neighborhood Hits	1371	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

NBEAL_HUMAN
NC score	0.050710 (rank : 103)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	153	Target Neighborhood Hits	200	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZS30, Q6Y876, Q6ZQY5, Q96Q30	Gene names	NBEAL1, ALS2CR17
Domain Architecture	No domain graphic available
Description	Neurobeachin-like 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein).

SWP70_MOUSE
NC score	0.050709 (rank : 104)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	153	Target Neighborhood Hits	1097	Shared Neighborhood Hits	36
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

OVOL1_HUMAN
NC score	0.047938 (rank : 105)	θ value	0.365318 (rank : 62)
Query Neighborhood Hits	153	Target Neighborhood Hits	729	Shared Neighborhood Hits	58
SwissProt Accessions	O14753, Q6PCB1	Gene names	OVOL1
Domain Architecture	No domain graphic available
Description	Putative transcription factor Ovo-like 1 (hOvo1).

OVOL2_MOUSE
NC score	0.047208 (rank : 106)	θ value	0.365318 (rank : 63)
Query Neighborhood Hits	153	Target Neighborhood Hits	709	Shared Neighborhood Hits	55
SwissProt Accessions	Q8CIV7, Q6F661, Q8CIV6, Q8K0D6, Q9D949	Gene names	Ovol2, Ovo2, Zfp339, Znf339
Domain Architecture	No domain graphic available
Description	Transcription factor Ovo-like 2 (mOvo2) (Zinc finger protein 339) (Zinc finger OVO2) (Zinc finger protein mOVO).

TRI25_MOUSE
NC score	0.046651 (rank : 107)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	153	Target Neighborhood Hits	446	Shared Neighborhood Hits	24
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

MELPH_HUMAN
NC score	0.045514 (rank : 108)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	153	Target Neighborhood Hits	145	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

ZFX_HUMAN
NC score	0.045033 (rank : 109)	θ value	0.163984 (rank : 57)
Query Neighborhood Hits	153	Target Neighborhood Hits	751	Shared Neighborhood Hits	56
SwissProt Accessions	P17010, O43668, Q8WYJ8	Gene names	ZFX
Domain Architecture
Description	Zinc finger X-chromosomal protein.

ZFX_MOUSE
NC score	0.044463 (rank : 110)	θ value	0.279714 (rank : 59)
Query Neighborhood Hits	153	Target Neighborhood Hits	748	Shared Neighborhood Hits	56
SwissProt Accessions	P17012, P17011	Gene names	Zfx
Domain Architecture
Description	Zinc finger X-chromosomal protein.

ZFA_MOUSE
NC score	0.044441 (rank : 111)	θ value	0.279714 (rank : 58)
Query Neighborhood Hits	153	Target Neighborhood Hits	746	Shared Neighborhood Hits	56
SwissProt Accessions	P23607	Gene names	Zfa
Domain Architecture
Description	Zinc finger autosomal protein.

ERC2_HUMAN
NC score	0.044172 (rank : 112)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	153	Target Neighborhood Hits	1156	Shared Neighborhood Hits	23
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ERC2_MOUSE
NC score	0.044165 (rank : 113)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	153	Target Neighborhood Hits	1166	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

ZFY_HUMAN
NC score	0.044039 (rank : 114)	θ value	0.365318 (rank : 65)
Query Neighborhood Hits	153	Target Neighborhood Hits	752	Shared Neighborhood Hits	56
SwissProt Accessions	P08048, Q14021, Q15558, Q96TF3	Gene names	ZFY
Domain Architecture
Description	Zinc finger Y-chromosomal protein.

OVOL2_HUMAN
NC score	0.043384 (rank : 115)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	153	Target Neighborhood Hits	715	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BRP0, Q5T8B4, Q9BX22, Q9HA54, Q9Y4M0	Gene names	OVOL2, ZNF339
Domain Architecture	No domain graphic available
Description	Transcription factor Ovo-like 2 (hOvo2) (Zinc finger protein 339).

TIF1B_MOUSE
NC score	0.043335 (rank : 116)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	153	Target Neighborhood Hits	276	Shared Neighborhood Hits	18
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

UB7I4_MOUSE
NC score	0.042664 (rank : 117)	θ value	0.813845 (rank : 70)
Query Neighborhood Hits	153	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

ZN507_HUMAN
NC score	0.042137 (rank : 118)	θ value	1.06291 (rank : 79)
Query Neighborhood Hits	153	Target Neighborhood Hits	739	Shared Neighborhood Hits	56
SwissProt Accessions	Q8TCN5	Gene names	ZNF507
Domain Architecture	No domain graphic available
Description	Zinc finger protein 507.

TIF1B_HUMAN
NC score	0.039938 (rank : 119)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	153	Target Neighborhood Hits	312	Shared Neighborhood Hits	17
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

ZN364_HUMAN
NC score	0.038853 (rank : 120)	θ value	1.06291 (rank : 78)
Query Neighborhood Hits	153	Target Neighborhood Hits	140	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

PLAL2_HUMAN
NC score	0.038461 (rank : 121)	θ value	0.365318 (rank : 64)
Query Neighborhood Hits	153	Target Neighborhood Hits	734	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UPG8, Q92584	Gene names	PLAGL2, KIAA0198
Domain Architecture	No domain graphic available
Description	Zinc finger protein PLAGL2 (Pleiomorphic adenoma-like protein 2).

STP2_MOUSE
NC score	0.037695 (rank : 122)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	153	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	P11378	Gene names	Tnp2
Domain Architecture	No domain graphic available
Description	Nuclear transition protein 2 (TP-2) (TP2).

SIP1_MOUSE
NC score	0.036085 (rank : 123)	θ value	1.06291 (rank : 74)
Query Neighborhood Hits	153	Target Neighborhood Hits	870	Shared Neighborhood Hits	55
SwissProt Accessions	Q9R0G7	Gene names	Zfhx1b, Sip1, Zfx1b
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1).

MAZ_HUMAN
NC score	0.035971 (rank : 124)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	153	Target Neighborhood Hits	757	Shared Neighborhood Hits	56
SwissProt Accessions	P56270, Q15703, Q99443	Gene names	MAZ
Domain Architecture	No domain graphic available
Description	Myc-associated zinc finger protein (MAZI) (Purine-binding transcription factor) (Pur-1) (ZF87) (ZIF87).

MAZ_MOUSE
NC score	0.035893 (rank : 125)	θ value	1.06291 (rank : 72)
Query Neighborhood Hits	153	Target Neighborhood Hits	745	Shared Neighborhood Hits	55
SwissProt Accessions	P56671, Q9R1W0	Gene names	Maz
Domain Architecture	No domain graphic available
Description	Myc-associated zinc finger protein (MAZI) (Purine-binding transcription factor) (Pur-1).

ZN343_HUMAN
NC score	0.035188 (rank : 126)	θ value	0.279714 (rank : 60)
Query Neighborhood Hits	153	Target Neighborhood Hits	768	Shared Neighborhood Hits	58
SwissProt Accessions	Q6P1L6, Q5JXU8, Q5JXU9, Q8N8F2, Q96EX8, Q96NA5, Q9BQB0	Gene names	ZNF343
Domain Architecture	No domain graphic available
Description	Zinc finger protein 343.

ZN184_HUMAN
NC score	0.035037 (rank : 127)	θ value	0.0736092 (rank : 55)
Query Neighborhood Hits	153	Target Neighborhood Hits	811	Shared Neighborhood Hits	60
SwissProt Accessions	Q99676, O60792, Q8TBA9	Gene names	ZNF184
Domain Architecture
Description	Zinc finger protein 184.

ZFP62_MOUSE
NC score	0.034857 (rank : 128)	θ value	1.06291 (rank : 77)
Query Neighborhood Hits	153	Target Neighborhood Hits	786	Shared Neighborhood Hits	61
SwissProt Accessions	Q8C827, Q3U3H0, Q62510, Q8BT00, Q8C2S6, Q8R5D1	Gene names	Zfp62
Domain Architecture	No domain graphic available
Description	Zinc finger protein 62 (Zfp-62) (ZT3).

ZN364_MOUSE
NC score	0.034822 (rank : 129)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	153	Target Neighborhood Hits	140	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

ZN341_HUMAN
NC score	0.034799 (rank : 130)	θ value	4.03905 (rank : 112)
Query Neighborhood Hits	153	Target Neighborhood Hits	803	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BYN7, Q5JXM8, Q96ST5	Gene names	ZNF341
Domain Architecture	No domain graphic available
Description	Zinc finger protein 341.

ZN564_HUMAN
NC score	0.034785 (rank : 131)	θ value	0.62314 (rank : 67)
Query Neighborhood Hits	153	Target Neighborhood Hits	746	Shared Neighborhood Hits	58
SwissProt Accessions	Q8TBZ8	Gene names	ZNF564
Domain Architecture	No domain graphic available
Description	Zinc finger protein 564.

ZFP62_HUMAN
NC score	0.034752 (rank : 132)	θ value	1.06291 (rank : 76)
Query Neighborhood Hits	153	Target Neighborhood Hits	768	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NB50	Gene names	ZFP62
Domain Architecture	No domain graphic available
Description	Zinc finger protein 62 homolog (Zfp-62).

ZNF28_HUMAN
NC score	0.034445 (rank : 133)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	153	Target Neighborhood Hits	760	Shared Neighborhood Hits	57
SwissProt Accessions	P17035, Q5HYM9, Q6ZML9, Q6ZN56	Gene names	ZNF28, KOX24
Domain Architecture	No domain graphic available
Description	Zinc finger protein 28 (Zinc finger protein KOX24).

ZBT17_HUMAN
NC score	0.034413 (rank : 134)	θ value	2.36792 (rank : 92)
Query Neighborhood Hits	153	Target Neighborhood Hits	925	Shared Neighborhood Hits	59
SwissProt Accessions	Q13105, Q15932, Q5JYB2, Q9NUC9	Gene names	ZBTB17, MIZ1, ZNF151
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 17 (Zinc finger protein 151) (Myc-interacting zinc finger protein) (Miz-1 protein).

ATBF1_MOUSE
NC score	0.033996 (rank : 135)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	153	Target Neighborhood Hits	1841	Shared Neighborhood Hits	66
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

EVI1_MOUSE
NC score	0.033910 (rank : 136)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	153	Target Neighborhood Hits	826	Shared Neighborhood Hits	58
SwissProt Accessions	P14404	Gene names	Evi1, Evi-1
Domain Architecture	No domain graphic available
Description	Ecotropic virus integration 1 site protein.

EVI1_HUMAN
NC score	0.033869 (rank : 137)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	153	Target Neighborhood Hits	924	Shared Neighborhood Hits	57
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

ZNF7_HUMAN
NC score	0.033837 (rank : 138)	θ value	0.62314 (rank : 68)
Query Neighborhood Hits	153	Target Neighborhood Hits	770	Shared Neighborhood Hits	57
SwissProt Accessions	P17097, P17015	Gene names	ZNF7, KOX4
Domain Architecture
Description	Zinc finger protein 7 (Zinc finger protein KOX4) (Zinc finger protein HF.16).

ZN148_MOUSE
NC score	0.033787 (rank : 139)	θ value	2.36792 (rank : 94)
Query Neighborhood Hits	153	Target Neighborhood Hits	755	Shared Neighborhood Hits	54
SwissProt Accessions	Q61624, P97475	Gene names	Znf148, Zbp89, Zfp148
Domain Architecture	No domain graphic available
Description	Zinc finger protein 148 (Zinc finger DNA-binding protein 89) (Transcription factor ZBP-89) (G-rich box-binding protein) (Beta enolase repressor factor 1) (Transcription factor BFCOL1).

ZN148_HUMAN
NC score	0.033785 (rank : 140)	θ value	2.36792 (rank : 93)
Query Neighborhood Hits	153	Target Neighborhood Hits	747	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UQR1, O00389, O43591	Gene names	ZNF148, ZBP89
Domain Architecture	No domain graphic available
Description	Zinc finger protein 148 (Zinc finger DNA-binding protein 89) (Transcription factor ZBP-89).

ZFP59_MOUSE
NC score	0.033684 (rank : 141)	θ value	1.06291 (rank : 75)
Query Neighborhood Hits	153	Target Neighborhood Hits	768	Shared Neighborhood Hits	57
SwissProt Accessions	P16373, Q61849	Gene names	Zfp59, Mfg2
Domain Architecture	No domain graphic available
Description	Zinc finger protein 59 (Zfp-59) (Zinc finger protein Mfg-2).

ZNF70_HUMAN
NC score	0.033153 (rank : 142)	θ value	1.38821 (rank : 83)
Query Neighborhood Hits	153	Target Neighborhood Hits	760	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UC06	Gene names	ZNF70
Domain Architecture	No domain graphic available
Description	Zinc finger protein 70 (Zinc finger protein N27C7-1).

ZN441_HUMAN
NC score	0.033096 (rank : 143)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	153	Target Neighborhood Hits	754	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N8Z8	Gene names	ZNF441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 441.

ZN236_HUMAN
NC score	0.032956 (rank : 144)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	153	Target Neighborhood Hits	844	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UL36, Q9UL37	Gene names	ZNF236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 236.

ZBT17_MOUSE
NC score	0.032867 (rank : 145)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	153	Target Neighborhood Hits	940	Shared Neighborhood Hits	57
SwissProt Accessions	Q60821, Q60699	Gene names	Zbtb17, Zfp100, Znf151
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 17 (Zinc finger protein 151) (Zinc finger protein 100) (Zfp-100) (Polyomavirus late initiator promoter-binding protein) (LP-1) (Zinc finger protein Z13).

ZN449_HUMAN
NC score	0.032798 (rank : 146)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	153	Target Neighborhood Hits	758	Shared Neighborhood Hits	59
SwissProt Accessions	Q6P9G9, Q5JRZ8, Q6NZX2, Q8N3Q1, Q8TED7	Gene names	ZNF449, ZSCAN19
Domain Architecture	No domain graphic available
Description	Zinc finger protein 449 (Zinc finger and SCAN domain-containing protein 19).

ZNF91_HUMAN
NC score	0.032763 (rank : 147)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	153	Target Neighborhood Hits	797	Shared Neighborhood Hits	60
SwissProt Accessions	Q05481	Gene names	ZNF91
Domain Architecture
Description	Zinc finger protein 91 (Zinc finger protein HTF10) (HPF7).

ZN11B_HUMAN
NC score	0.032640 (rank : 148)	θ value	4.03905 (rank : 110)
Query Neighborhood Hits	153	Target Neighborhood Hits	802	Shared Neighborhood Hits	66
SwissProt Accessions	Q06732, Q86XY8, Q8NDW3	Gene names	ZNF11B
Domain Architecture	No domain graphic available
Description	Zinc finger protein 11B.

MYH6_HUMAN
NC score	0.032370 (rank : 149)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	153	Target Neighborhood Hits	1426	Shared Neighborhood Hits	21
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

ZN433_HUMAN
NC score	0.032267 (rank : 150)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	153	Target Neighborhood Hits	782	Shared Neighborhood Hits	65
SwissProt Accessions	Q8N7K0	Gene names	ZNF433
Domain Architecture
Description	Zinc finger protein 433.

ZN678_HUMAN
NC score	0.032241 (rank : 151)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	153	Target Neighborhood Hits	761	Shared Neighborhood Hits	60
SwissProt Accessions	Q5SXM1, Q8IVQ9	Gene names	ZNF678
Domain Architecture	No domain graphic available
Description	Zinc finger protein 678.

ZN471_HUMAN
NC score	0.032168 (rank : 152)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	153	Target Neighborhood Hits	771	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BX82, O75260, Q8N3V1, Q9P2F1	Gene names	ZNF471, ERP1, KIAA1396
Domain Architecture
Description	Zinc finger protein 471 (EZFIT-related protein 1).

ZN136_HUMAN
NC score	0.032137 (rank : 153)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	153	Target Neighborhood Hits	739	Shared Neighborhood Hits	59
SwissProt Accessions	P52737	Gene names	ZNF136
Domain Architecture
Description	Zinc finger protein 136.

ZN307_HUMAN
NC score	0.031878 (rank : 154)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	153	Target Neighborhood Hits	750	Shared Neighborhood Hits	59
SwissProt Accessions	Q969J2	Gene names	ZNF307
Domain Architecture
Description	Zinc finger protein 307 (P373c6.1).

MYH6_MOUSE
NC score	0.031635 (rank : 155)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	153	Target Neighborhood Hits	1501	Shared Neighborhood Hits	20
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

ZN408_HUMAN
NC score	0.031527 (rank : 156)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	153	Target Neighborhood Hits	775	Shared Neighborhood Hits	58
SwissProt Accessions	Q9H9D4	Gene names	ZNF408, PFM14, PRDM17
Domain Architecture	No domain graphic available
Description	Zinc finger protein 408 (PR-domain zinc finger protein 17).

ZN182_HUMAN
NC score	0.031510 (rank : 157)	θ value	4.03905 (rank : 111)
Query Neighborhood Hits	153	Target Neighborhood Hits	759	Shared Neighborhood Hits	58
SwissProt Accessions	P17025, Q3KP67	Gene names	ZNF182, KOX14, ZNF21
Domain Architecture	No domain graphic available
Description	Zinc finger protein 182 (Zinc finger protein 21) (Zinc finger protein KOX14).

TRI46_MOUSE
NC score	0.031485 (rank : 158)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	153	Target Neighborhood Hits	287	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

ZN672_HUMAN
NC score	0.031433 (rank : 159)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	153	Target Neighborhood Hits	744	Shared Neighborhood Hits	58
SwissProt Accessions	Q499Z4, Q96H65, Q96IM3, Q9H6G5	Gene names	ZNF672
Domain Architecture	No domain graphic available
Description	Zinc finger protein 672.

ZN669_HUMAN
NC score	0.031410 (rank : 160)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	153	Target Neighborhood Hits	746	Shared Neighborhood Hits	60
SwissProt Accessions	Q96BR6, Q5VT39, Q9H9Q6	Gene names	ZNF669
Domain Architecture	No domain graphic available
Description	Zinc finger protein 669.

MYH7_HUMAN
NC score	0.031395 (rank : 161)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	153	Target Neighborhood Hits	1559	Shared Neighborhood Hits	21
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

ZNF34_HUMAN
NC score	0.031341 (rank : 162)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	153	Target Neighborhood Hits	760	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IZ26	Gene names	ZNF34, KOX32
Domain Architecture	No domain graphic available
Description	Zinc finger protein 34 (Zinc finger protein KOX32).

RAD21_HUMAN
NC score	0.031209 (rank : 163)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	153	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	O60216, Q15001, Q99568	Gene names	RAD21, HR21, KIAA0078, NXP1
Domain Architecture
Description	Double-strand-break repair protein rad21 homolog (hHR21) (Nuclear matrix protein 1) (NXP-1) (SCC1 homolog).

ZN677_HUMAN
NC score	0.031190 (rank : 164)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	153	Target Neighborhood Hits	761	Shared Neighborhood Hits	59
SwissProt Accessions	Q86XU0	Gene names	ZNF677
Domain Architecture	No domain graphic available
Description	Zinc finger protein 677.

RAD21_MOUSE
NC score	0.031020 (rank : 165)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	153	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q61550, P70219, Q91VB9, Q9DBU4	Gene names	Rad21, Hr21
Domain Architecture
Description	Double-strand-break repair protein rad21 homolog (Pokeweed agglutinin- binding protein 29) (PW29) (SCC1 homolog).

ZN224_HUMAN
NC score	0.030992 (rank : 166)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	153	Target Neighborhood Hits	808	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NZL3, Q86V10, Q8IZC8, Q9UID9, Q9Y2P6	Gene names	ZNF224, BMZF2, ZNF255
Domain Architecture
Description	Zinc finger protein 224 (Zinc finger protein 255) (Bone marrow zinc finger 2) (BMZF-2).

ZN542_HUMAN
NC score	0.030890 (rank : 167)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	153	Target Neighborhood Hits	735	Shared Neighborhood Hits	59
SwissProt Accessions	Q5EBM4, Q6N061	Gene names	ZNF542
Domain Architecture	No domain graphic available
Description	Zinc finger protein 542.

ATBF1_HUMAN
NC score	0.030842 (rank : 168)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	153	Target Neighborhood Hits	1547	Shared Neighborhood Hits	62
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

ZN250_HUMAN
NC score	0.030397 (rank : 169)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	153	Target Neighborhood Hits	756	Shared Neighborhood Hits	58
SwissProt Accessions	P15622, Q8N942, Q96AH9	Gene names	ZNF250, ZNF647
Domain Architecture	No domain graphic available
Description	Zinc finger protein 250 (Zinc finger protein 647).

ZN248_HUMAN
NC score	0.029748 (rank : 170)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	153	Target Neighborhood Hits	749	Shared Neighborhood Hits	59
SwissProt Accessions	Q8NDW4, Q9UMP3	Gene names	ZNF248
Domain Architecture
Description	Zinc finger protein 248.

ZNHI3_MOUSE
NC score	0.029450 (rank : 171)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	153	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CQK1	Gene names	Znhit3, Trip3
Domain Architecture	No domain graphic available
Description	Zinc finger HIT domain-containing protein 3 (Thyroid receptor- interacting protein 3) (TRIP-3) (Thyroid hormone receptor interactor 3).

TRI46_HUMAN
NC score	0.028244 (rank : 172)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	153	Target Neighborhood Hits	291	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

UB7I4_HUMAN
NC score	0.028116 (rank : 173)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	153	Target Neighborhood Hits	54	Shared Neighborhood Hits	6
SwissProt Accessions	P50876	Gene names	RNF144, KIAA0161, UBCE7IP4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

ZN346_HUMAN
NC score	0.023484 (rank : 174)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	153	Target Neighborhood Hits	64	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UL40, Q68CV9, Q6ZMW1	Gene names	ZNF346, JAZ
Domain Architecture	No domain graphic available
Description	Zinc finger protein 346 (Just another zinc finger protein).

CGHB_HUMAN
NC score	0.022470 (rank : 175)	θ value	2.36792 (rank : 88)
Query Neighborhood Hits	153	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	P01233, Q13991, Q14000, Q3SY41, Q8WTT5, Q8WXL2, Q8WXL3, Q8WXL4	Gene names	CGB, CGB3
Domain Architecture
Description	Choriogonadotropin subunit beta precursor (CG-beta) (Chorionic gonadotrophin chain beta).

IF2P_HUMAN
NC score	0.020635 (rank : 176)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	153	Target Neighborhood Hits	889	Shared Neighborhood Hits	17
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

FHL3_HUMAN
NC score	0.019136 (rank : 177)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	153	Target Neighborhood Hits	354	Shared Neighborhood Hits	25
SwissProt Accessions	Q13643	Gene names	FHL3, SLIM2
Domain Architecture
Description	Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM- protein 2) (SLIM 2).

C2TA_MOUSE
NC score	0.018458 (rank : 178)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	153	Target Neighborhood Hits	131	Shared Neighborhood Hits	3
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

CBP_HUMAN
NC score	0.017900 (rank : 179)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	153	Target Neighborhood Hits	941	Shared Neighborhood Hits	17
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

FHL1_MOUSE
NC score	0.016019 (rank : 180)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	153	Target Neighborhood Hits	462	Shared Neighborhood Hits	34
SwissProt Accessions	P97447, O55181, Q8K318	Gene names	Fhl1
Domain Architecture
Description	Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM- protein 1) (SLIM 1) (SLIM) (KyoT) (RBP-associated molecule 14-1) (RAM14-1).

EP300_HUMAN
NC score	0.015421 (rank : 181)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	153	Target Neighborhood Hits	821	Shared Neighborhood Hits	13
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

ARD1_HUMAN
NC score	0.013689 (rank : 182)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	153	Target Neighborhood Hits	621	Shared Neighborhood Hits	39
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

RP3A_MOUSE
NC score	0.013202 (rank : 183)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	153	Target Neighborhood Hits	510	Shared Neighborhood Hits	13
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

TAF1_HUMAN
NC score	0.012065 (rank : 184)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	153	Target Neighborhood Hits	136	Shared Neighborhood Hits	6
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

MLL3_HUMAN
NC score	0.011972 (rank : 185)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	153	Target Neighborhood Hits	1644	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

DNMT2_HUMAN
NC score	0.011772 (rank : 186)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	153	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	O14717, O43669	Gene names	DNMT2
Domain Architecture
Description	tRNA (cytosine-5-)-methyltransferase (EC 2.1.1.29) (DNA (cytosine-5)- methyltransferase-like protein 2) (Dnmt2) (DNA methyltransferase homolog HsaIIP) (DNA MTase homolog HsaIIP) (M.HsaIIP) (PuMet).

FRAS1_HUMAN
NC score	0.009735 (rank : 187)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	153	Target Neighborhood Hits	759	Shared Neighborhood Hits	31
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

MEGF8_HUMAN
NC score	0.007886 (rank : 188)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	153	Target Neighborhood Hits	528	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

INADL_HUMAN
NC score	0.007532 (rank : 189)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	153	Target Neighborhood Hits	260	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

EPHB6_HUMAN
NC score	-0.000006 (rank : 190)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	153	Target Neighborhood Hits	912	Shared Neighborhood Hits	6
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

EPHB6_MOUSE
NC score	-0.000079 (rank : 191)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	153	Target Neighborhood Hits	906	Shared Neighborhood Hits	6
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

MYLK_HUMAN
NC score	-0.005394 (rank : 192)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	153	Target Neighborhood Hits	1328	Shared Neighborhood Hits	4
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).