Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : DNMT2_HUMAN

For an explanation of this page, click here

DNMT2_HUMAN
SwissProt Accessions	O14717, O43669	Gene names	DNMT2
Domain Architecture
Description	tRNA (cytosine-5-)-methyltransferase (EC 2.1.1.29) (DNA (cytosine-5)- methyltransferase-like protein 2) (Dnmt2) (DNA methyltransferase homolog HsaIIP) (DNA MTase homolog HsaIIP) (M.HsaIIP) (PuMet).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DNMT2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	O14717, O43669	Gene names	DNMT2
Domain Architecture
Description	tRNA (cytosine-5-)-methyltransferase (EC 2.1.1.29) (DNA (cytosine-5)- methyltransferase-like protein 2) (Dnmt2) (DNA methyltransferase homolog HsaIIP) (DNA MTase homolog HsaIIP) (M.HsaIIP) (PuMet).

DNMT2_MOUSE
θ value	1.19313e-177 (rank : 2)	NC score	0.991412 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	O55055, O35212	Gene names	Dnmt2, Met2
Domain Architecture
Description	tRNA (cytosine-5-)-methyltransferase (EC 2.1.1.29) (DNA (cytosine-5)- methyltransferase-like protein 2) (Dnmt2) (DNA methyltransferase homolog MmuIIP) (DNA MTase homolog MmuIIP) (M.MmuIIP) (Met-2).

DNMT1_MOUSE
θ value	8.97725e-08 (rank : 3)	NC score	0.300631 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	137	Shared Neighborhood Hits	6
SwissProt Accessions	P13864, P97413, Q80ZU3, Q9CSC6, Q9QXX6	Gene names	Dnmt1, Dnmt, Met1, Uim
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase MmuI) (DNA MTase MmuI) (MCMT) (M.MmuI) (Met-1).

DNMT1_HUMAN
θ value	5.81887e-07 (rank : 4)	NC score	0.267664 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	401	Shared Neighborhood Hits	5
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

MDN1_HUMAN
θ value	0.0330416 (rank : 5)	NC score	0.083555 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	662	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

PIAS1_HUMAN
θ value	0.813845 (rank : 6)	NC score	0.041328 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	O75925, Q99751, Q9UN02	Gene names	PIAS1, DDXBP1
Domain Architecture
Description	Protein inhibitor of activated STAT protein 1 (Gu-binding protein) (GBP) (RNA helicase II-binding protein) (DEAD/H box-binding protein 1).

PIAS1_MOUSE
θ value	0.813845 (rank : 7)	NC score	0.041341 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	O88907, Q8C6H5	Gene names	Pias1, Ddxbp1
Domain Architecture
Description	Protein inhibitor of activated STAT protein 1 (DEAD/H box-binding protein 1).

DNM3B_MOUSE
θ value	1.81305 (rank : 8)	NC score	0.039539 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	O88509, O88510, O88511	Gene names	Dnmt3b
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase MmuIIIB) (DNA MTase MmuIIIB) (M.MmuIIIB).

DNM3B_HUMAN
θ value	2.36792 (rank : 9)	NC score	0.037670 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBC3, Q9UBD4, Q9UJQ5, Q9UKA6, Q9UNE5, Q9Y5R9, Q9Y5S0	Gene names	DNMT3B
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase HsaIIIB) (DNA MTase HsaIIIB) (M.HsaIIIB).

MUCDL_MOUSE
θ value	3.0926 (rank : 10)	NC score	0.017593 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	461	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

EMSY_HUMAN
θ value	5.27518 (rank : 11)	NC score	0.018713 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	296	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

MACF1_MOUSE
θ value	8.99809 (rank : 12)	NC score	0.003438 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	1313	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

TAF1L_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.018710 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	144	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IZX4	Gene names	TAF1L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID 210 kDa subunit (TBP-associated factor 210 kDa) (TAF(II)210) (TBP-associated factor 1-like).

TAF1_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.018006 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	136	Shared Neighborhood Hits	4
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

TM1L1_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.012100 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	O75674	Gene names	TOM1L1, SRCASM
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).

ZFYV1_MOUSE
θ value	8.99809 (rank : 16)	NC score	0.011772 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	153	Shared Neighborhood Hits	3
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

Hits sorted by NC score

DNMT2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	O14717, O43669	Gene names	DNMT2
Domain Architecture
Description	tRNA (cytosine-5-)-methyltransferase (EC 2.1.1.29) (DNA (cytosine-5)- methyltransferase-like protein 2) (Dnmt2) (DNA methyltransferase homolog HsaIIP) (DNA MTase homolog HsaIIP) (M.HsaIIP) (PuMet).

DNMT2_MOUSE
NC score	0.991412 (rank : 2)	θ value	1.19313e-177 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	O55055, O35212	Gene names	Dnmt2, Met2
Domain Architecture
Description	tRNA (cytosine-5-)-methyltransferase (EC 2.1.1.29) (DNA (cytosine-5)- methyltransferase-like protein 2) (Dnmt2) (DNA methyltransferase homolog MmuIIP) (DNA MTase homolog MmuIIP) (M.MmuIIP) (Met-2).

DNMT1_MOUSE
NC score	0.300631 (rank : 3)	θ value	8.97725e-08 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	137	Shared Neighborhood Hits	6
SwissProt Accessions	P13864, P97413, Q80ZU3, Q9CSC6, Q9QXX6	Gene names	Dnmt1, Dnmt, Met1, Uim
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase MmuI) (DNA MTase MmuI) (MCMT) (M.MmuI) (Met-1).

DNMT1_HUMAN
NC score	0.267664 (rank : 4)	θ value	5.81887e-07 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	401	Shared Neighborhood Hits	5
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

MDN1_HUMAN
NC score	0.083555 (rank : 5)	θ value	0.0330416 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	662	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

PIAS1_MOUSE
NC score	0.041341 (rank : 6)	θ value	0.813845 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	O88907, Q8C6H5	Gene names	Pias1, Ddxbp1
Domain Architecture
Description	Protein inhibitor of activated STAT protein 1 (DEAD/H box-binding protein 1).

PIAS1_HUMAN
NC score	0.041328 (rank : 7)	θ value	0.813845 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	O75925, Q99751, Q9UN02	Gene names	PIAS1, DDXBP1
Domain Architecture
Description	Protein inhibitor of activated STAT protein 1 (Gu-binding protein) (GBP) (RNA helicase II-binding protein) (DEAD/H box-binding protein 1).

DNM3B_MOUSE
NC score	0.039539 (rank : 8)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	O88509, O88510, O88511	Gene names	Dnmt3b
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase MmuIIIB) (DNA MTase MmuIIIB) (M.MmuIIIB).

DNM3B_HUMAN
NC score	0.037670 (rank : 9)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBC3, Q9UBD4, Q9UJQ5, Q9UKA6, Q9UNE5, Q9Y5R9, Q9Y5S0	Gene names	DNMT3B
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase HsaIIIB) (DNA MTase HsaIIIB) (M.HsaIIIB).

EMSY_HUMAN
NC score	0.018713 (rank : 10)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	296	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

TAF1L_HUMAN
NC score	0.018710 (rank : 11)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	144	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IZX4	Gene names	TAF1L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID 210 kDa subunit (TBP-associated factor 210 kDa) (TAF(II)210) (TBP-associated factor 1-like).

TAF1_HUMAN
NC score	0.018006 (rank : 12)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	136	Shared Neighborhood Hits	4
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

MUCDL_MOUSE
NC score	0.017593 (rank : 13)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	461	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

TM1L1_HUMAN
NC score	0.012100 (rank : 14)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	O75674	Gene names	TOM1L1, SRCASM
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).

ZFYV1_MOUSE
NC score	0.011772 (rank : 15)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	153	Shared Neighborhood Hits	3
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

MACF1_MOUSE
NC score	0.003438 (rank : 16)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	1313	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).