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Network neighborhood for query Sequence : ZFY16_HUMAN

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ZFY16_HUMAN
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ZFY16_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	125	Target Neighborhood Hits	125	Shared Neighborhood Hits	125
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

ZFY16_MOUSE
θ value	0 (rank : 2)	NC score	0.983444 (rank : 2)
Query Neighborhood Hits	125	Target Neighborhood Hits	108	Shared Neighborhood Hits	62
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

ZFYV9_HUMAN
θ value	0 (rank : 3)	NC score	0.947491 (rank : 3)
Query Neighborhood Hits	125	Target Neighborhood Hits	134	Shared Neighborhood Hits	59
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

FGD6_HUMAN
θ value	1.38178e-16 (rank : 4)	NC score	0.545512 (rank : 12)
Query Neighborhood Hits	125	Target Neighborhood Hits	237	Shared Neighborhood Hits	53
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD6_MOUSE
θ value	5.25075e-16 (rank : 5)	NC score	0.533390 (rank : 16)
Query Neighborhood Hits	125	Target Neighborhood Hits	282	Shared Neighborhood Hits	51
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

ZFY21_MOUSE
θ value	4.91457e-14 (rank : 6)	NC score	0.726606 (rank : 4)
Query Neighborhood Hits	125	Target Neighborhood Hits	72	Shared Neighborhood Hits	54
SwissProt Accessions	Q8VCM3, Q9D1E2	Gene names	Zfyve21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

FGD5_HUMAN
θ value	2.43908e-13 (rank : 7)	NC score	0.539289 (rank : 14)
Query Neighborhood Hits	125	Target Neighborhood Hits	235	Shared Neighborhood Hits	54
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

ZFY21_HUMAN
θ value	2.43908e-13 (rank : 8)	NC score	0.718822 (rank : 5)
Query Neighborhood Hits	125	Target Neighborhood Hits	72	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BQ24, Q86T05, Q96LT1	Gene names	ZFYVE21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

HGS_MOUSE
θ value	5.43371e-13 (rank : 9)	NC score	0.528832 (rank : 18)
Query Neighborhood Hits	125	Target Neighborhood Hits	589	Shared Neighborhood Hits	56
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HGS_HUMAN
θ value	1.58096e-12 (rank : 10)	NC score	0.529031 (rank : 17)
Query Neighborhood Hits	125	Target Neighborhood Hits	517	Shared Neighborhood Hits	55
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

FYV1_HUMAN
θ value	2.69671e-12 (rank : 11)	NC score	0.509479 (rank : 19)
Query Neighborhood Hits	125	Target Neighborhood Hits	217	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

FGD4_HUMAN
θ value	3.52202e-12 (rank : 12)	NC score	0.465681 (rank : 24)
Query Neighborhood Hits	125	Target Neighborhood Hits	219	Shared Neighborhood Hits	49
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD5_MOUSE
θ value	3.52202e-12 (rank : 13)	NC score	0.547082 (rank : 11)
Query Neighborhood Hits	125	Target Neighborhood Hits	170	Shared Neighborhood Hits	54
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

FYV1_MOUSE
θ value	3.52202e-12 (rank : 14)	NC score	0.506885 (rank : 20)
Query Neighborhood Hits	125	Target Neighborhood Hits	191	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

FYCO1_HUMAN
θ value	4.59992e-12 (rank : 15)	NC score	0.271554 (rank : 45)
Query Neighborhood Hits	125	Target Neighborhood Hits	1149	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

PKHF2_HUMAN
θ value	7.84624e-12 (rank : 16)	NC score	0.659119 (rank : 8)
Query Neighborhood Hits	125	Target Neighborhood Hits	75	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

PKHF2_MOUSE
θ value	7.84624e-12 (rank : 17)	NC score	0.659670 (rank : 7)
Query Neighborhood Hits	125	Target Neighborhood Hits	77	Shared Neighborhood Hits	48
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

FGD4_MOUSE
θ value	1.02475e-11 (rank : 18)	NC score	0.461930 (rank : 26)
Query Neighborhood Hits	125	Target Neighborhood Hits	227	Shared Neighborhood Hits	48
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGD1_MOUSE
θ value	1.74796e-11 (rank : 19)	NC score	0.459735 (rank : 27)
Query Neighborhood Hits	125	Target Neighborhood Hits	387	Shared Neighborhood Hits	50
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD2_MOUSE
θ value	2.28291e-11 (rank : 20)	NC score	0.484468 (rank : 21)
Query Neighborhood Hits	125	Target Neighborhood Hits	163	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

MTMR3_HUMAN
θ value	3.89403e-11 (rank : 21)	NC score	0.389122 (rank : 34)
Query Neighborhood Hits	125	Target Neighborhood Hits	163	Shared Neighborhood Hits	54
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

RUFY2_HUMAN
θ value	3.89403e-11 (rank : 22)	NC score	0.298917 (rank : 44)
Query Neighborhood Hits	125	Target Neighborhood Hits	1208	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

FGD1_HUMAN
θ value	5.08577e-11 (rank : 23)	NC score	0.458899 (rank : 28)
Query Neighborhood Hits	125	Target Neighborhood Hits	367	Shared Neighborhood Hits	50
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD2_HUMAN
θ value	5.08577e-11 (rank : 24)	NC score	0.483962 (rank : 22)
Query Neighborhood Hits	125	Target Neighborhood Hits	151	Shared Neighborhood Hits	50
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

FYCO1_MOUSE
θ value	8.67504e-11 (rank : 25)	NC score	0.252002 (rank : 47)
Query Neighborhood Hits	125	Target Neighborhood Hits	1059	Shared Neighborhood Hits	57
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

RUFY1_MOUSE
θ value	8.67504e-11 (rank : 26)	NC score	0.378348 (rank : 36)
Query Neighborhood Hits	125	Target Neighborhood Hits	765	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

EEA1_MOUSE
θ value	1.47974e-10 (rank : 27)	NC score	0.226768 (rank : 49)
Query Neighborhood Hits	125	Target Neighborhood Hits	1637	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

RUFY1_HUMAN
θ value	1.9326e-10 (rank : 28)	NC score	0.370120 (rank : 40)
Query Neighborhood Hits	125	Target Neighborhood Hits	848	Shared Neighborhood Hits	60
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

RUFY2_MOUSE
θ value	1.9326e-10 (rank : 29)	NC score	0.373518 (rank : 38)
Query Neighborhood Hits	125	Target Neighborhood Hits	820	Shared Neighborhood Hits	61
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

ZFY28_HUMAN
θ value	2.52405e-10 (rank : 30)	NC score	0.671720 (rank : 6)
Query Neighborhood Hits	125	Target Neighborhood Hits	152	Shared Neighborhood Hits	55
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

EEA1_HUMAN
θ value	4.30538e-10 (rank : 31)	NC score	0.209125 (rank : 50)
Query Neighborhood Hits	125	Target Neighborhood Hits	1796	Shared Neighborhood Hits	67
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

WDFY3_MOUSE
θ value	1.25267e-09 (rank : 32)	NC score	0.374237 (rank : 37)
Query Neighborhood Hits	125	Target Neighborhood Hits	332	Shared Neighborhood Hits	58
SwissProt Accessions	Q6VNB8, Q8C8H7	Gene names	Wdfy3
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1).

WDFY3_HUMAN
θ value	1.63604e-09 (rank : 33)	NC score	0.372749 (rank : 39)
Query Neighborhood Hits	125	Target Neighborhood Hits	348	Shared Neighborhood Hits	58
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

PKHF1_MOUSE
θ value	2.13673e-09 (rank : 34)	NC score	0.642571 (rank : 10)
Query Neighborhood Hits	125	Target Neighborhood Hits	80	Shared Neighborhood Hits	50
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

PKHF1_HUMAN
θ value	2.79066e-09 (rank : 35)	NC score	0.646248 (rank : 9)
Query Neighborhood Hits	125	Target Neighborhood Hits	76	Shared Neighborhood Hits	50
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

ANFY1_MOUSE
θ value	2.36244e-08 (rank : 36)	NC score	0.252027 (rank : 46)
Query Neighborhood Hits	125	Target Neighborhood Hits	480	Shared Neighborhood Hits	57
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

DSPP_HUMAN
θ value	6.87365e-08 (rank : 37)	NC score	0.106399 (rank : 67)
Query Neighborhood Hits	125	Target Neighborhood Hits	645	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

ZFYV1_HUMAN
θ value	6.87365e-08 (rank : 38)	NC score	0.540492 (rank : 13)
Query Neighborhood Hits	125	Target Neighborhood Hits	166	Shared Neighborhood Hits	55
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

ZFYV1_MOUSE
θ value	8.97725e-08 (rank : 39)	NC score	0.536831 (rank : 15)
Query Neighborhood Hits	125	Target Neighborhood Hits	153	Shared Neighborhood Hits	58
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

ANFY1_HUMAN
θ value	4.45536e-07 (rank : 40)	NC score	0.246892 (rank : 48)
Query Neighborhood Hits	125	Target Neighborhood Hits	480	Shared Neighborhood Hits	55
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

FGD3_HUMAN
θ value	5.81887e-07 (rank : 41)	NC score	0.422982 (rank : 31)
Query Neighborhood Hits	125	Target Neighborhood Hits	249	Shared Neighborhood Hits	56
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

WDFY2_HUMAN
θ value	3.77169e-06 (rank : 42)	NC score	0.361030 (rank : 43)
Query Neighborhood Hits	125	Target Neighborhood Hits	332	Shared Neighborhood Hits	51
SwissProt Accessions	Q96P53, Q96CS1	Gene names	WDFY2, WDF2, ZFYVE22
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2) (Zinc finger FYVE domain-containing protein 22).

WDFY2_MOUSE
θ value	3.77169e-06 (rank : 43)	NC score	0.363861 (rank : 42)
Query Neighborhood Hits	125	Target Neighborhood Hits	337	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BUB4	Gene names	Wdfy2
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2).

RBNS5_HUMAN
θ value	4.92598e-06 (rank : 44)	NC score	0.468950 (rank : 23)
Query Neighborhood Hits	125	Target Neighborhood Hits	242	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

RBNS5_MOUSE
θ value	4.92598e-06 (rank : 45)	NC score	0.464873 (rank : 25)
Query Neighborhood Hits	125	Target Neighborhood Hits	266	Shared Neighborhood Hits	49
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

FGD3_MOUSE
θ value	1.43324e-05 (rank : 46)	NC score	0.383885 (rank : 35)
Query Neighborhood Hits	125	Target Neighborhood Hits	257	Shared Neighborhood Hits	54
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

WDFY1_HUMAN
θ value	1.43324e-05 (rank : 47)	NC score	0.369723 (rank : 41)
Query Neighborhood Hits	125	Target Neighborhood Hits	305	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IWB7, Q9H9D5, Q9P2B3	Gene names	WDFY1, KIAA1435, WDF1, ZFYVE17
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 1 (WD40- and FYVE domain- containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain-containing protein 17).

DSPP_MOUSE
θ value	0.00020696 (rank : 48)	NC score	0.093249 (rank : 74)
Query Neighborhood Hits	125	Target Neighborhood Hits	491	Shared Neighborhood Hits	15
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

ZFY27_HUMAN
θ value	0.000270298 (rank : 49)	NC score	0.393501 (rank : 33)
Query Neighborhood Hits	125	Target Neighborhood Hits	64	Shared Neighborhood Hits	44
SwissProt Accessions	Q5T4F4, Q5T4F1, Q5T4F2, Q5T4F3, Q8N1K0, Q8N6D6, Q8NCA0, Q8NDE4, Q96M08	Gene names	ZFYVE27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

ZFY19_HUMAN
θ value	0.00035302 (rank : 50)	NC score	0.458555 (rank : 29)
Query Neighborhood Hits	125	Target Neighborhood Hits	206	Shared Neighborhood Hits	53
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

ZFY19_MOUSE
θ value	0.00035302 (rank : 51)	NC score	0.451573 (rank : 30)
Query Neighborhood Hits	125	Target Neighborhood Hits	143	Shared Neighborhood Hits	55
SwissProt Accessions	Q9DAZ9, Q8VCV7	Gene names	Zfyve19
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19.

ZFY27_MOUSE
θ value	0.00035302 (rank : 52)	NC score	0.399661 (rank : 32)
Query Neighborhood Hits	125	Target Neighborhood Hits	53	Shared Neighborhood Hits	44
SwissProt Accessions	Q3TXX3, Q8CFP8	Gene names	Zfyve27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

RFFL_MOUSE
θ value	0.0148317 (rank : 53)	NC score	0.187972 (rank : 51)
Query Neighborhood Hits	125	Target Neighborhood Hits	145	Shared Neighborhood Hits	35
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

MYST4_HUMAN
θ value	0.0252991 (rank : 54)	NC score	0.031062 (rank : 133)
Query Neighborhood Hits	125	Target Neighborhood Hits	671	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

RNF34_HUMAN
θ value	0.0330416 (rank : 55)	NC score	0.177297 (rank : 53)
Query Neighborhood Hits	125	Target Neighborhood Hits	153	Shared Neighborhood Hits	33
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RNF34_MOUSE
θ value	0.0431538 (rank : 56)	NC score	0.177785 (rank : 52)
Query Neighborhood Hits	125	Target Neighborhood Hits	160	Shared Neighborhood Hits	35
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RFFL_HUMAN
θ value	0.0563607 (rank : 57)	NC score	0.174657 (rank : 54)
Query Neighborhood Hits	125	Target Neighborhood Hits	175	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

WDR37_HUMAN
θ value	0.0563607 (rank : 58)	NC score	0.043672 (rank : 117)
Query Neighborhood Hits	125	Target Neighborhood Hits	303	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2I8, Q5SW03, Q9NTJ6	Gene names	WDR37, KIAA0982
Domain Architecture
Description	WD repeat protein 37.

WDR37_MOUSE
θ value	0.0563607 (rank : 59)	NC score	0.042458 (rank : 118)
Query Neighborhood Hits	125	Target Neighborhood Hits	298	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CBE3, Q80Y96, Q8CCL2	Gene names	Wdr37, Kiaa0982
Domain Architecture
Description	WD repeat protein 37.

BIN1_MOUSE
θ value	0.0736092 (rank : 60)	NC score	0.032009 (rank : 132)
Query Neighborhood Hits	125	Target Neighborhood Hits	283	Shared Neighborhood Hits	3
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

AIM1_HUMAN
θ value	0.0961366 (rank : 61)	NC score	0.037478 (rank : 121)
Query Neighborhood Hits	125	Target Neighborhood Hits	247	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

GFRA2_MOUSE
θ value	0.163984 (rank : 62)	NC score	0.032807 (rank : 131)
Query Neighborhood Hits	125	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	O08842	Gene names	Gfra2, Gdnfrb, Trnr2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta).

ZN295_HUMAN
θ value	0.21417 (rank : 63)	NC score	0.011464 (rank : 157)
Query Neighborhood Hits	125	Target Neighborhood Hits	847	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ULJ3, Q6P4R0	Gene names	ZNF295, KIAA1227, ZBTB21
Domain Architecture
Description	Zinc finger protein 295 (Zinc finger and BTB domain-containing protein 21).

CP4AC_MOUSE
θ value	0.365318 (rank : 64)	NC score	0.008898 (rank : 161)
Query Neighborhood Hits	125	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	Q91WL5, Q3UNE4, Q6P931, Q8N7N3	Gene names	Cyp4a12
Domain Architecture	No domain graphic available
Description	Cytochrome P450 4A12 (EC 1.14.14.1) (CYPIVA12).

IMA5_HUMAN
θ value	0.365318 (rank : 65)	NC score	0.036438 (rank : 122)
Query Neighborhood Hits	125	Target Neighborhood Hits	68	Shared Neighborhood Hits	6
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

WEE1B_HUMAN
θ value	0.365318 (rank : 66)	NC score	0.007057 (rank : 165)
Query Neighborhood Hits	125	Target Neighborhood Hits	836	Shared Neighborhood Hits	4
SwissProt Accessions	P0C1S8	Gene names	WEE1B, WEE2
Domain Architecture	No domain graphic available
Description	Wee1-like protein kinase 1B (EC 2.7.10.2) (Wee1B kinase).

CAC1H_HUMAN
θ value	0.47712 (rank : 67)	NC score	0.012086 (rank : 154)
Query Neighborhood Hits	125	Target Neighborhood Hits	307	Shared Neighborhood Hits	4
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

IMA1_HUMAN
θ value	0.813845 (rank : 68)	NC score	0.035505 (rank : 123)
Query Neighborhood Hits	125	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	P52294, Q9BQ56	Gene names	KPNA1, RCH2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (NPI-1).

SP2_HUMAN
θ value	0.813845 (rank : 69)	NC score	0.005567 (rank : 169)
Query Neighborhood Hits	125	Target Neighborhood Hits	747	Shared Neighborhood Hits	14
SwissProt Accessions	Q02086	Gene names	SP2, KIAA0048
Domain Architecture
Description	Transcription factor Sp2.

CEP35_HUMAN
θ value	1.06291 (rank : 70)	NC score	0.037518 (rank : 120)
Query Neighborhood Hits	125	Target Neighborhood Hits	811	Shared Neighborhood Hits	19
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

SCAR3_HUMAN
θ value	1.06291 (rank : 71)	NC score	0.017501 (rank : 148)
Query Neighborhood Hits	125	Target Neighborhood Hits	205	Shared Neighborhood Hits	5
SwissProt Accessions	Q6AZY7, Q9UM15, Q9UM16	Gene names	SCARA3, CSR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class A member 3 (Cellular stress response gene protein).

ZN230_HUMAN
θ value	1.06291 (rank : 72)	NC score	0.001034 (rank : 179)
Query Neighborhood Hits	125	Target Neighborhood Hits	750	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UIE0, O15322, Q9P1U6	Gene names	ZNF230, FDZF2
Domain Architecture
Description	Zinc finger protein 230 (Zinc finger protein FDZF2).

CC14A_HUMAN
θ value	1.38821 (rank : 73)	NC score	0.016739 (rank : 150)
Query Neighborhood Hits	125	Target Neighborhood Hits	133	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

IMA1_MOUSE
θ value	1.38821 (rank : 74)	NC score	0.034338 (rank : 126)
Query Neighborhood Hits	125	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q60960, Q3TF32	Gene names	Kpna1, Rch2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (Importin alpha S1).

IMA7_MOUSE
θ value	1.38821 (rank : 75)	NC score	0.033854 (rank : 128)
Query Neighborhood Hits	125	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	O35345, Q9CVP9	Gene names	Kpna6, Kpna5
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6 subunit) (Importin alpha S2).

PODXL_HUMAN
θ value	1.38821 (rank : 76)	NC score	0.023732 (rank : 137)
Query Neighborhood Hits	125	Target Neighborhood Hits	191	Shared Neighborhood Hits	5
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

RFIP1_MOUSE
θ value	1.38821 (rank : 77)	NC score	0.018946 (rank : 146)
Query Neighborhood Hits	125	Target Neighborhood Hits	152	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

SYCP1_HUMAN
θ value	1.38821 (rank : 78)	NC score	0.035018 (rank : 125)
Query Neighborhood Hits	125	Target Neighborhood Hits	1313	Shared Neighborhood Hits	19
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

DMRT1_MOUSE
θ value	1.81305 (rank : 79)	NC score	0.021523 (rank : 141)
Query Neighborhood Hits	125	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZ59, Q9QZ37, Q9QZA4	Gene names	Dmrt1
Domain Architecture
Description	Doublesex- and mab-3-related transcription factor 1.

FINC_MOUSE
θ value	1.81305 (rank : 80)	NC score	0.007041 (rank : 166)
Query Neighborhood Hits	125	Target Neighborhood Hits	309	Shared Neighborhood Hits	4
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

GOGA4_HUMAN
θ value	1.81305 (rank : 81)	NC score	0.037744 (rank : 119)
Query Neighborhood Hits	125	Target Neighborhood Hits	2034	Shared Neighborhood Hits	27
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

IMA7_HUMAN
θ value	1.81305 (rank : 82)	NC score	0.033264 (rank : 130)
Query Neighborhood Hits	125	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	O60684	Gene names	KPNA6, IPOA7
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6).

NEB1_HUMAN
θ value	1.81305 (rank : 83)	NC score	0.035261 (rank : 124)
Query Neighborhood Hits	125	Target Neighborhood Hits	829	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

SAFB1_HUMAN
θ value	1.81305 (rank : 84)	NC score	0.016166 (rank : 151)
Query Neighborhood Hits	125	Target Neighborhood Hits	493	Shared Neighborhood Hits	9
SwissProt Accessions	Q15424, O60406, Q59HH8	Gene names	SAFB, HAP, HET, SAFB1
Domain Architecture
Description	Scaffold attachment factor B (Scaffold attachment factor B1) (SAF-B) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE- TATA-binding protein).

SAS10_HUMAN
θ value	1.81305 (rank : 85)	NC score	0.023112 (rank : 138)
Query Neighborhood Hits	125	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQZ2, Q6FI82	Gene names	CRLZ1, SAS10
Domain Architecture	No domain graphic available
Description	Something about silencing protein 10 (Disrupter of silencing SAS10) (Charged amino acid-rich leucine zipper 1).

ZN408_HUMAN
θ value	1.81305 (rank : 86)	NC score	0.001415 (rank : 177)
Query Neighborhood Hits	125	Target Neighborhood Hits	775	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H9D4	Gene names	ZNF408, PFM14, PRDM17
Domain Architecture	No domain graphic available
Description	Zinc finger protein 408 (PR-domain zinc finger protein 17).

AFTIN_MOUSE
θ value	2.36792 (rank : 87)	NC score	0.033877 (rank : 127)
Query Neighborhood Hits	125	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	Q80WT5, Q5SSE6, Q99KJ1	Gene names	Aftph, Afth
Domain Architecture	No domain graphic available
Description	Aftiphilin.

ANR12_HUMAN
θ value	2.36792 (rank : 88)	NC score	0.020558 (rank : 143)
Query Neighborhood Hits	125	Target Neighborhood Hits	1081	Shared Neighborhood Hits	17
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

MUC13_HUMAN
θ value	2.36792 (rank : 89)	NC score	0.021589 (rank : 140)
Query Neighborhood Hits	125	Target Neighborhood Hits	164	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

NU153_HUMAN
θ value	2.36792 (rank : 90)	NC score	0.030215 (rank : 134)
Query Neighborhood Hits	125	Target Neighborhood Hits	227	Shared Neighborhood Hits	13
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

WEE1B_MOUSE
θ value	2.36792 (rank : 91)	NC score	0.004674 (rank : 171)
Query Neighborhood Hits	125	Target Neighborhood Hits	765	Shared Neighborhood Hits	3
SwissProt Accessions	Q66JT0, Q4U4S4, Q7TPV9	Gene names	Wee1b, Wee2
Domain Architecture	No domain graphic available
Description	Wee1-like protein kinase 1B (EC 2.7.10.2) (Wee1B kinase) (mWee1B).

DGKG_HUMAN
θ value	3.0926 (rank : 92)	NC score	0.010160 (rank : 158)
Query Neighborhood Hits	125	Target Neighborhood Hits	171	Shared Neighborhood Hits	3
SwissProt Accessions	P49619	Gene names	DGKG, DAGK3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma).

GFRA2_HUMAN
θ value	3.0926 (rank : 93)	NC score	0.023930 (rank : 136)
Query Neighborhood Hits	125	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	O00451, O15316, O15328, Q7Z5C2	Gene names	GFRA2, GDNFRB, RETL2, TRNR2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta) (RET ligand 2).

ZN317_HUMAN
θ value	3.0926 (rank : 94)	NC score	0.000869 (rank : 183)
Query Neighborhood Hits	125	Target Neighborhood Hits	759	Shared Neighborhood Hits	17
SwissProt Accessions	Q96PQ6, Q96PM0, Q96PM1, Q96PT2	Gene names	ZNF317
Domain Architecture
Description	Zinc finger protein 317.

CND2_HUMAN
θ value	4.03905 (rank : 95)	NC score	0.022077 (rank : 139)
Query Neighborhood Hits	125	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q15003, Q8TB87	Gene names	NCAPH, BRRN, BRRN1, CAPH, KIAA0074
Domain Architecture
Description	Condensin complex subunit 2 (Non-SMC condensin I complex subunit H) (Barren homolog protein 1) (Chromosome-associated protein H) (hCAP-H) (XCAP-H homolog).

MAGBI_HUMAN
θ value	4.03905 (rank : 96)	NC score	0.005141 (rank : 170)
Query Neighborhood Hits	125	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q96M61	Gene names	MAGEB18
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen B18 (MAGE-B18 antigen).

PCD12_HUMAN
θ value	4.03905 (rank : 97)	NC score	0.000995 (rank : 180)
Query Neighborhood Hits	125	Target Neighborhood Hits	203	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NPG4, Q6UXB6, Q96KB8, Q9H7Y6, Q9H8E0	Gene names	PCDH12
Domain Architecture
Description	Protocadherin-12 precursor (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cadherin-2) (VE-cad-2).

ZAN_HUMAN
θ value	4.03905 (rank : 98)	NC score	0.006147 (rank : 168)
Query Neighborhood Hits	125	Target Neighborhood Hits	679	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ZN555_HUMAN
θ value	4.03905 (rank : 99)	NC score	-0.000154 (rank : 184)
Query Neighborhood Hits	125	Target Neighborhood Hits	741	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NEP9, Q8NA46, Q96MP1	Gene names	ZNF555
Domain Architecture	No domain graphic available
Description	Zinc finger protein 555.

ZN699_HUMAN
θ value	4.03905 (rank : 100)	NC score	0.000932 (rank : 182)
Query Neighborhood Hits	125	Target Neighborhood Hits	773	Shared Neighborhood Hits	21
SwissProt Accessions	Q32M78, Q8N9A1	Gene names	ZNF699
Domain Architecture	No domain graphic available
Description	Zinc finger protein 699 (Hangover homolog).

ZO3_HUMAN
θ value	4.03905 (rank : 101)	NC score	0.006627 (rank : 167)
Query Neighborhood Hits	125	Target Neighborhood Hits	219	Shared Neighborhood Hits	5
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

CEP57_MOUSE
θ value	5.27518 (rank : 102)	NC score	0.033514 (rank : 129)
Query Neighborhood Hits	125	Target Neighborhood Hits	580	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

CND2_MOUSE
θ value	5.27518 (rank : 103)	NC score	0.021074 (rank : 142)
Query Neighborhood Hits	125	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C156, Q8BY01, Q8VDM9	Gene names	Ncaph, Brrn, Brrn1, Caph
Domain Architecture
Description	Condensin complex subunit 2 (Non-SMC condensin I complex subunit H) (Barren homolog protein 1) (Chromosome-associated protein H) (mCAP-H) (XCAP-H homolog).

DCR1A_HUMAN
θ value	5.27518 (rank : 104)	NC score	0.011607 (rank : 155)
Query Neighborhood Hits	125	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PJP8, Q14701, Q6P5Y3, Q6PKL4	Gene names	DCLRE1A, KIAA0086, SNM1, SNM1A
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein (hSNM1) (hSNM1A).

DGKG_MOUSE
θ value	5.27518 (rank : 105)	NC score	0.008839 (rank : 162)
Query Neighborhood Hits	125	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WG7	Gene names	Dgkg, Dagk3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma) (88 kDa diacylglycerol kinase).

DLG7_HUMAN
θ value	5.27518 (rank : 106)	NC score	0.012374 (rank : 153)
Query Neighborhood Hits	125	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q15398, Q8NG58	Gene names	DLG7, KIAA0008
Domain Architecture
Description	Discs large homolog 7 (Hepatoma up-regulated protein) (HURP).

EAF2_HUMAN
θ value	5.27518 (rank : 107)	NC score	0.013667 (rank : 152)
Query Neighborhood Hits	125	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q96CJ1, Q9NZ82	Gene names	EAF2, TRAITS
Domain Architecture	No domain graphic available
Description	ELL-associated factor 2 (Testosterone-regulated apoptosis inducer and tumor suppressor protein).

K2027_HUMAN
θ value	5.27518 (rank : 108)	NC score	0.019032 (rank : 145)
Query Neighborhood Hits	125	Target Neighborhood Hits	194	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

NR1H2_MOUSE
θ value	5.27518 (rank : 109)	NC score	0.002197 (rank : 173)
Query Neighborhood Hits	125	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	Q60644	Gene names	Nr1h2, Lxrb, Rip15, Unr, Unr2
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Retinoid X receptor-interacting protein No.15).

T2FA_HUMAN
θ value	5.27518 (rank : 110)	NC score	0.019714 (rank : 144)
Query Neighborhood Hits	125	Target Neighborhood Hits	228	Shared Neighborhood Hits	9
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

AFAD_HUMAN
θ value	6.88961 (rank : 111)	NC score	0.008995 (rank : 160)
Query Neighborhood Hits	125	Target Neighborhood Hits	689	Shared Neighborhood Hits	9
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

CNTP3_HUMAN
θ value	6.88961 (rank : 112)	NC score	0.003569 (rank : 172)
Query Neighborhood Hits	125	Target Neighborhood Hits	195	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

CUBN_HUMAN
θ value	6.88961 (rank : 113)	NC score	-0.000156 (rank : 185)
Query Neighborhood Hits	125	Target Neighborhood Hits	482	Shared Neighborhood Hits	5
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

PO2F1_HUMAN
θ value	6.88961 (rank : 114)	NC score	0.001854 (rank : 174)
Query Neighborhood Hits	125	Target Neighborhood Hits	426	Shared Neighborhood Hits	4
SwissProt Accessions	P14859, Q5TBT7, Q6PK46, Q8NEU9, Q9BPV1	Gene names	POU2F1, OCT1, OTF1
Domain Architecture
Description	POU domain, class 2, transcription factor 1 (Octamer-binding transcription factor 1) (Oct-1) (OTF-1) (NF-A1).

RBP2_MOUSE
θ value	6.88961 (rank : 115)	NC score	0.007807 (rank : 163)
Query Neighborhood Hits	125	Target Neighborhood Hits	232	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

TRI37_MOUSE
θ value	6.88961 (rank : 116)	NC score	0.007467 (rank : 164)
Query Neighborhood Hits	125	Target Neighborhood Hits	316	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

ZFY1_MOUSE
θ value	6.88961 (rank : 117)	NC score	0.001067 (rank : 178)
Query Neighborhood Hits	125	Target Neighborhood Hits	790	Shared Neighborhood Hits	17
SwissProt Accessions	P10925	Gene names	Zfy1, Zfy-1
Domain Architecture
Description	Zinc finger Y-chromosomal protein 1.

ARID2_HUMAN
θ value	8.99809 (rank : 118)	NC score	0.011502 (rank : 156)
Query Neighborhood Hits	125	Target Neighborhood Hits	302	Shared Neighborhood Hits	6
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

MAZ_HUMAN
θ value	8.99809 (rank : 119)	NC score	0.001470 (rank : 175)
Query Neighborhood Hits	125	Target Neighborhood Hits	757	Shared Neighborhood Hits	14
SwissProt Accessions	P56270, Q15703, Q99443	Gene names	MAZ
Domain Architecture	No domain graphic available
Description	Myc-associated zinc finger protein (MAZI) (Purine-binding transcription factor) (Pur-1) (ZF87) (ZIF87).

MAZ_MOUSE
θ value	8.99809 (rank : 120)	NC score	0.001432 (rank : 176)
Query Neighborhood Hits	125	Target Neighborhood Hits	745	Shared Neighborhood Hits	14
SwissProt Accessions	P56671, Q9R1W0	Gene names	Maz
Domain Architecture	No domain graphic available
Description	Myc-associated zinc finger protein (MAZI) (Purine-binding transcription factor) (Pur-1).

SDPR_HUMAN
θ value	8.99809 (rank : 121)	NC score	0.026276 (rank : 135)
Query Neighborhood Hits	125	Target Neighborhood Hits	337	Shared Neighborhood Hits	14
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

SMYD5_MOUSE
θ value	8.99809 (rank : 122)	NC score	0.009089 (rank : 159)
Query Neighborhood Hits	125	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q3TYX3, Q3TRB2, Q91YL6	Gene names	Smyd5
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 5 (Protein NN8-4AG).

TP53B_HUMAN
θ value	8.99809 (rank : 123)	NC score	0.017230 (rank : 149)
Query Neighborhood Hits	125	Target Neighborhood Hits	413	Shared Neighborhood Hits	12
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TP53B_MOUSE
θ value	8.99809 (rank : 124)	NC score	0.018639 (rank : 147)
Query Neighborhood Hits	125	Target Neighborhood Hits	644	Shared Neighborhood Hits	14
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

VEZF1_HUMAN
θ value	8.99809 (rank : 125)	NC score	0.000980 (rank : 181)
Query Neighborhood Hits	125	Target Neighborhood Hits	744	Shared Neighborhood Hits	13
SwissProt Accessions	Q14119	Gene names	VEZF1, DB1, ZNF161
Domain Architecture	No domain graphic available
Description	Vascular endothelial zinc finger 1 (Zinc finger protein 161) (Putative transcription factor DB1).

ABR_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.082540 (rank : 85)
Query Neighborhood Hits	125	Target Neighborhood Hits	166	Shared Neighborhood Hits	12
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

ALS2_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.053169 (rank : 109)
Query Neighborhood Hits	125	Target Neighborhood Hits	111	Shared Neighborhood Hits	13
SwissProt Accessions	Q920R0, Q8JZR1, Q9CXJ3	Gene names	Als2
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2 homolog).

ARHG1_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.082165 (rank : 86)
Query Neighborhood Hits	125	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

ARHG1_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.081413 (rank : 87)
Query Neighborhood Hits	125	Target Neighborhood Hits	266	Shared Neighborhood Hits	14
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ARHG2_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.068471 (rank : 91)
Query Neighborhood Hits	125	Target Neighborhood Hits	142	Shared Neighborhood Hits	12
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

ARHG2_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.093870 (rank : 73)
Query Neighborhood Hits	125	Target Neighborhood Hits	120	Shared Neighborhood Hits	14
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

ARHG3_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.052788 (rank : 112)
Query Neighborhood Hits	125	Target Neighborhood Hits	82	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

ARHG3_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.054645 (rank : 106)
Query Neighborhood Hits	125	Target Neighborhood Hits	85	Shared Neighborhood Hits	9
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

ARHG4_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.084947 (rank : 80)
Query Neighborhood Hits	125	Target Neighborhood Hits	242	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG4_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.084254 (rank : 81)
Query Neighborhood Hits	125	Target Neighborhood Hits	185	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG5_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.115256 (rank : 64)
Query Neighborhood Hits	125	Target Neighborhood Hits	172	Shared Neighborhood Hits	13
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

ARHG7_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.063408 (rank : 101)
Query Neighborhood Hits	125	Target Neighborhood Hits	347	Shared Neighborhood Hits	14
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

ARHG7_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.052648 (rank : 113)
Query Neighborhood Hits	125	Target Neighborhood Hits	396	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

ARHG8_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.053050 (rank : 110)
Query Neighborhood Hits	125	Target Neighborhood Hits	85	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

ARHG9_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.079060 (rank : 88)
Query Neighborhood Hits	125	Target Neighborhood Hits	235	Shared Neighborhood Hits	12
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.077734 (rank : 90)
Query Neighborhood Hits	125	Target Neighborhood Hits	234	Shared Neighborhood Hits	11
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

ARHGA_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.108949 (rank : 66)
Query Neighborhood Hits	125	Target Neighborhood Hits	187	Shared Neighborhood Hits	16
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGA_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.109695 (rank : 65)
Query Neighborhood Hits	125	Target Neighborhood Hits	125	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGB_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.065621 (rank : 96)
Query Neighborhood Hits	125	Target Neighborhood Hits	375	Shared Neighborhood Hits	14
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

ARHGC_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.064810 (rank : 98)
Query Neighborhood Hits	125	Target Neighborhood Hits	351	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.064012 (rank : 99)
Query Neighborhood Hits	125	Target Neighborhood Hits	344	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGF_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.100205 (rank : 70)
Query Neighborhood Hits	125	Target Neighborhood Hits	214	Shared Neighborhood Hits	13
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ARHGG_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.099910 (rank : 71)
Query Neighborhood Hits	125	Target Neighborhood Hits	129	Shared Neighborhood Hits	13
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ARHGG_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.092554 (rank : 75)
Query Neighborhood Hits	125	Target Neighborhood Hits	152	Shared Neighborhood Hits	13
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

BCR_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.084035 (rank : 83)
Query Neighborhood Hits	125	Target Neighborhood Hits	204	Shared Neighborhood Hits	12
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

CJ064_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.078945 (rank : 89)
Query Neighborhood Hits	125	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZS81, Q8N4A3	Gene names	C10orf64
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf64.

ECT2_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.129160 (rank : 60)
Query Neighborhood Hits	125	Target Neighborhood Hits	98	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ECT2_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.132545 (rank : 59)
Query Neighborhood Hits	125	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

FARP1_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.136383 (rank : 58)
Query Neighborhood Hits	125	Target Neighborhood Hits	241	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FARP2_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.140941 (rank : 55)
Query Neighborhood Hits	125	Target Neighborhood Hits	240	Shared Neighborhood Hits	18
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.139686 (rank : 56)
Query Neighborhood Hits	125	Target Neighborhood Hits	209	Shared Neighborhood Hits	16
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

GNRP_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.084251 (rank : 82)
Query Neighborhood Hits	125	Target Neighborhood Hits	239	Shared Neighborhood Hits	16
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

GNRP_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.083740 (rank : 84)
Query Neighborhood Hits	125	Target Neighborhood Hits	191	Shared Neighborhood Hits	13
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

HAPIP_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.105517 (rank : 68)
Query Neighborhood Hits	125	Target Neighborhood Hits	350	Shared Neighborhood Hits	20
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

ITSN1_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.067752 (rank : 93)
Query Neighborhood Hits	125	Target Neighborhood Hits	1757	Shared Neighborhood Hits	34
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.067815 (rank : 92)
Query Neighborhood Hits	125	Target Neighborhood Hits	1669	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN2_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.067523 (rank : 94)
Query Neighborhood Hits	125	Target Neighborhood Hits	1173	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN2_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.067498 (rank : 95)
Query Neighborhood Hits	125	Target Neighborhood Hits	1371	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

LBC_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.086057 (rank : 79)
Query Neighborhood Hits	125	Target Neighborhood Hits	90	Shared Neighborhood Hits	12
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

MCF2L_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.091079 (rank : 76)
Query Neighborhood Hits	125	Target Neighborhood Hits	255	Shared Neighborhood Hits	16
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

MCF2_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.090044 (rank : 77)
Query Neighborhood Hits	125	Target Neighborhood Hits	166	Shared Neighborhood Hits	14
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

NBEAL_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.055177 (rank : 105)
Query Neighborhood Hits	125	Target Neighborhood Hits	200	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZS30, Q6Y876, Q6ZQY5, Q96Q30	Gene names	NBEAL1, ALS2CR17
Domain Architecture	No domain graphic available
Description	Neurobeachin-like 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein).

NGEF_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.102749 (rank : 69)
Query Neighborhood Hits	125	Target Neighborhood Hits	166	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

NGEF_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.099775 (rank : 72)
Query Neighborhood Hits	125	Target Neighborhood Hits	228	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

PKHA6_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.063277 (rank : 102)
Query Neighborhood Hits	125	Target Neighborhood Hits	556	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.060560 (rank : 103)
Query Neighborhood Hits	125	Target Neighborhood Hits	591	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHG1_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.115853 (rank : 63)
Query Neighborhood Hits	125	Target Neighborhood Hits	174	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

PKHG4_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.088461 (rank : 78)
Query Neighborhood Hits	125	Target Neighborhood Hits	200	Shared Neighborhood Hits	12
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

PREX1_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.138099 (rank : 57)
Query Neighborhood Hits	125	Target Neighborhood Hits	177	Shared Neighborhood Hits	19
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

RUFY3_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.116360 (rank : 62)
Query Neighborhood Hits	125	Target Neighborhood Hits	594	Shared Neighborhood Hits	12
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

RUFY3_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.117456 (rank : 61)
Query Neighborhood Hits	125	Target Neighborhood Hits	579	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

SWP70_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.053265 (rank : 108)
Query Neighborhood Hits	125	Target Neighborhood Hits	973	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.050740 (rank : 116)
Query Neighborhood Hits	125	Target Neighborhood Hits	1097	Shared Neighborhood Hits	33
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

TIAM1_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.065588 (rank : 97)
Query Neighborhood Hits	125	Target Neighborhood Hits	225	Shared Neighborhood Hits	13
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TIAM1_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.063631 (rank : 100)
Query Neighborhood Hits	125	Target Neighborhood Hits	205	Shared Neighborhood Hits	13
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

VAV2_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.053040 (rank : 111)
Query Neighborhood Hits	125	Target Neighborhood Hits	456	Shared Neighborhood Hits	16
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VAV3_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.051964 (rank : 114)
Query Neighborhood Hits	125	Target Neighborhood Hits	398	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.051291 (rank : 115)
Query Neighborhood Hits	125	Target Neighborhood Hits	404	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VAV_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.056854 (rank : 104)
Query Neighborhood Hits	125	Target Neighborhood Hits	452	Shared Neighborhood Hits	14
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VAV_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.054320 (rank : 107)
Query Neighborhood Hits	125	Target Neighborhood Hits	430	Shared Neighborhood Hits	14
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

Hits sorted by NC score

ZFY16_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	125	Target Neighborhood Hits	125	Shared Neighborhood Hits	125
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

ZFY16_MOUSE
NC score	0.983444 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	125	Target Neighborhood Hits	108	Shared Neighborhood Hits	62
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

ZFYV9_HUMAN
NC score	0.947491 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	125	Target Neighborhood Hits	134	Shared Neighborhood Hits	59
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

ZFY21_MOUSE
NC score	0.726606 (rank : 4)	θ value	4.91457e-14 (rank : 6)
Query Neighborhood Hits	125	Target Neighborhood Hits	72	Shared Neighborhood Hits	54
SwissProt Accessions	Q8VCM3, Q9D1E2	Gene names	Zfyve21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY21_HUMAN
NC score	0.718822 (rank : 5)	θ value	2.43908e-13 (rank : 8)
Query Neighborhood Hits	125	Target Neighborhood Hits	72	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BQ24, Q86T05, Q96LT1	Gene names	ZFYVE21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY28_HUMAN
NC score	0.671720 (rank : 6)	θ value	2.52405e-10 (rank : 30)
Query Neighborhood Hits	125	Target Neighborhood Hits	152	Shared Neighborhood Hits	55
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

PKHF2_MOUSE
NC score	0.659670 (rank : 7)	θ value	7.84624e-12 (rank : 17)
Query Neighborhood Hits	125	Target Neighborhood Hits	77	Shared Neighborhood Hits	48
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

PKHF2_HUMAN
NC score	0.659119 (rank : 8)	θ value	7.84624e-12 (rank : 16)
Query Neighborhood Hits	125	Target Neighborhood Hits	75	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

PKHF1_HUMAN
NC score	0.646248 (rank : 9)	θ value	2.79066e-09 (rank : 35)
Query Neighborhood Hits	125	Target Neighborhood Hits	76	Shared Neighborhood Hits	50
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

PKHF1_MOUSE
NC score	0.642571 (rank : 10)	θ value	2.13673e-09 (rank : 34)
Query Neighborhood Hits	125	Target Neighborhood Hits	80	Shared Neighborhood Hits	50
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

FGD5_MOUSE
NC score	0.547082 (rank : 11)	θ value	3.52202e-12 (rank : 13)
Query Neighborhood Hits	125	Target Neighborhood Hits	170	Shared Neighborhood Hits	54
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

FGD6_HUMAN
NC score	0.545512 (rank : 12)	θ value	1.38178e-16 (rank : 4)
Query Neighborhood Hits	125	Target Neighborhood Hits	237	Shared Neighborhood Hits	53
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

ZFYV1_HUMAN
NC score	0.540492 (rank : 13)	θ value	6.87365e-08 (rank : 38)
Query Neighborhood Hits	125	Target Neighborhood Hits	166	Shared Neighborhood Hits	55
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

FGD5_HUMAN
NC score	0.539289 (rank : 14)	θ value	2.43908e-13 (rank : 7)
Query Neighborhood Hits	125	Target Neighborhood Hits	235	Shared Neighborhood Hits	54
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

ZFYV1_MOUSE
NC score	0.536831 (rank : 15)	θ value	8.97725e-08 (rank : 39)
Query Neighborhood Hits	125	Target Neighborhood Hits	153	Shared Neighborhood Hits	58
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

FGD6_MOUSE
NC score	0.533390 (rank : 16)	θ value	5.25075e-16 (rank : 5)
Query Neighborhood Hits	125	Target Neighborhood Hits	282	Shared Neighborhood Hits	51
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

HGS_HUMAN
NC score	0.529031 (rank : 17)	θ value	1.58096e-12 (rank : 10)
Query Neighborhood Hits	125	Target Neighborhood Hits	517	Shared Neighborhood Hits	55
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HGS_MOUSE
NC score	0.528832 (rank : 18)	θ value	5.43371e-13 (rank : 9)
Query Neighborhood Hits	125	Target Neighborhood Hits	589	Shared Neighborhood Hits	56
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

FYV1_HUMAN
NC score	0.509479 (rank : 19)	θ value	2.69671e-12 (rank : 11)
Query Neighborhood Hits	125	Target Neighborhood Hits	217	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

FYV1_MOUSE
NC score	0.506885 (rank : 20)	θ value	3.52202e-12 (rank : 14)
Query Neighborhood Hits	125	Target Neighborhood Hits	191	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

FGD2_MOUSE
NC score	0.484468 (rank : 21)	θ value	2.28291e-11 (rank : 20)
Query Neighborhood Hits	125	Target Neighborhood Hits	163	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

FGD2_HUMAN
NC score	0.483962 (rank : 22)	θ value	5.08577e-11 (rank : 24)
Query Neighborhood Hits	125	Target Neighborhood Hits	151	Shared Neighborhood Hits	50
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

RBNS5_HUMAN
NC score	0.468950 (rank : 23)	θ value	4.92598e-06 (rank : 44)
Query Neighborhood Hits	125	Target Neighborhood Hits	242	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

FGD4_HUMAN
NC score	0.465681 (rank : 24)	θ value	3.52202e-12 (rank : 12)
Query Neighborhood Hits	125	Target Neighborhood Hits	219	Shared Neighborhood Hits	49
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

RBNS5_MOUSE
NC score	0.464873 (rank : 25)	θ value	4.92598e-06 (rank : 45)
Query Neighborhood Hits	125	Target Neighborhood Hits	266	Shared Neighborhood Hits	49
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

FGD4_MOUSE
NC score	0.461930 (rank : 26)	θ value	1.02475e-11 (rank : 18)
Query Neighborhood Hits	125	Target Neighborhood Hits	227	Shared Neighborhood Hits	48
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGD1_MOUSE
NC score	0.459735 (rank : 27)	θ value	1.74796e-11 (rank : 19)
Query Neighborhood Hits	125	Target Neighborhood Hits	387	Shared Neighborhood Hits	50
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_HUMAN
NC score	0.458899 (rank : 28)	θ value	5.08577e-11 (rank : 23)
Query Neighborhood Hits	125	Target Neighborhood Hits	367	Shared Neighborhood Hits	50
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

ZFY19_HUMAN
NC score	0.458555 (rank : 29)	θ value	0.00035302 (rank : 50)
Query Neighborhood Hits	125	Target Neighborhood Hits	206	Shared Neighborhood Hits	53
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

ZFY19_MOUSE
NC score	0.451573 (rank : 30)	θ value	0.00035302 (rank : 51)
Query Neighborhood Hits	125	Target Neighborhood Hits	143	Shared Neighborhood Hits	55
SwissProt Accessions	Q9DAZ9, Q8VCV7	Gene names	Zfyve19
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19.

FGD3_HUMAN
NC score	0.422982 (rank : 31)	θ value	5.81887e-07 (rank : 41)
Query Neighborhood Hits	125	Target Neighborhood Hits	249	Shared Neighborhood Hits	56
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

ZFY27_MOUSE
NC score	0.399661 (rank : 32)	θ value	0.00035302 (rank : 52)
Query Neighborhood Hits	125	Target Neighborhood Hits	53	Shared Neighborhood Hits	44
SwissProt Accessions	Q3TXX3, Q8CFP8	Gene names	Zfyve27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

ZFY27_HUMAN
NC score	0.393501 (rank : 33)	θ value	0.000270298 (rank : 49)
Query Neighborhood Hits	125	Target Neighborhood Hits	64	Shared Neighborhood Hits	44
SwissProt Accessions	Q5T4F4, Q5T4F1, Q5T4F2, Q5T4F3, Q8N1K0, Q8N6D6, Q8NCA0, Q8NDE4, Q96M08	Gene names	ZFYVE27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

MTMR3_HUMAN
NC score	0.389122 (rank : 34)	θ value	3.89403e-11 (rank : 21)
Query Neighborhood Hits	125	Target Neighborhood Hits	163	Shared Neighborhood Hits	54
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

FGD3_MOUSE
NC score	0.383885 (rank : 35)	θ value	1.43324e-05 (rank : 46)
Query Neighborhood Hits	125	Target Neighborhood Hits	257	Shared Neighborhood Hits	54
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

RUFY1_MOUSE
NC score	0.378348 (rank : 36)	θ value	8.67504e-11 (rank : 26)
Query Neighborhood Hits	125	Target Neighborhood Hits	765	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

WDFY3_MOUSE
NC score	0.374237 (rank : 37)	θ value	1.25267e-09 (rank : 32)
Query Neighborhood Hits	125	Target Neighborhood Hits	332	Shared Neighborhood Hits	58
SwissProt Accessions	Q6VNB8, Q8C8H7	Gene names	Wdfy3
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1).

RUFY2_MOUSE
NC score	0.373518 (rank : 38)	θ value	1.9326e-10 (rank : 29)
Query Neighborhood Hits	125	Target Neighborhood Hits	820	Shared Neighborhood Hits	61
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

WDFY3_HUMAN
NC score	0.372749 (rank : 39)	θ value	1.63604e-09 (rank : 33)
Query Neighborhood Hits	125	Target Neighborhood Hits	348	Shared Neighborhood Hits	58
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

RUFY1_HUMAN
NC score	0.370120 (rank : 40)	θ value	1.9326e-10 (rank : 28)
Query Neighborhood Hits	125	Target Neighborhood Hits	848	Shared Neighborhood Hits	60
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

WDFY1_HUMAN
NC score	0.369723 (rank : 41)	θ value	1.43324e-05 (rank : 47)
Query Neighborhood Hits	125	Target Neighborhood Hits	305	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IWB7, Q9H9D5, Q9P2B3	Gene names	WDFY1, KIAA1435, WDF1, ZFYVE17
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 1 (WD40- and FYVE domain- containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain-containing protein 17).

WDFY2_MOUSE
NC score	0.363861 (rank : 42)	θ value	3.77169e-06 (rank : 43)
Query Neighborhood Hits	125	Target Neighborhood Hits	337	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BUB4	Gene names	Wdfy2
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2).

WDFY2_HUMAN
NC score	0.361030 (rank : 43)	θ value	3.77169e-06 (rank : 42)
Query Neighborhood Hits	125	Target Neighborhood Hits	332	Shared Neighborhood Hits	51
SwissProt Accessions	Q96P53, Q96CS1	Gene names	WDFY2, WDF2, ZFYVE22
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2) (Zinc finger FYVE domain-containing protein 22).

RUFY2_HUMAN
NC score	0.298917 (rank : 44)	θ value	3.89403e-11 (rank : 22)
Query Neighborhood Hits	125	Target Neighborhood Hits	1208	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

FYCO1_HUMAN
NC score	0.271554 (rank : 45)	θ value	4.59992e-12 (rank : 15)
Query Neighborhood Hits	125	Target Neighborhood Hits	1149	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

ANFY1_MOUSE
NC score	0.252027 (rank : 46)	θ value	2.36244e-08 (rank : 36)
Query Neighborhood Hits	125	Target Neighborhood Hits	480	Shared Neighborhood Hits	57
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

FYCO1_MOUSE
NC score	0.252002 (rank : 47)	θ value	8.67504e-11 (rank : 25)
Query Neighborhood Hits	125	Target Neighborhood Hits	1059	Shared Neighborhood Hits	57
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

ANFY1_HUMAN
NC score	0.246892 (rank : 48)	θ value	4.45536e-07 (rank : 40)
Query Neighborhood Hits	125	Target Neighborhood Hits	480	Shared Neighborhood Hits	55
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

EEA1_MOUSE
NC score	0.226768 (rank : 49)	θ value	1.47974e-10 (rank : 27)
Query Neighborhood Hits	125	Target Neighborhood Hits	1637	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

EEA1_HUMAN
NC score	0.209125 (rank : 50)	θ value	4.30538e-10 (rank : 31)
Query Neighborhood Hits	125	Target Neighborhood Hits	1796	Shared Neighborhood Hits	67
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

RFFL_MOUSE
NC score	0.187972 (rank : 51)	θ value	0.0148317 (rank : 53)
Query Neighborhood Hits	125	Target Neighborhood Hits	145	Shared Neighborhood Hits	35
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RNF34_MOUSE
NC score	0.177785 (rank : 52)	θ value	0.0431538 (rank : 56)
Query Neighborhood Hits	125	Target Neighborhood Hits	160	Shared Neighborhood Hits	35
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RNF34_HUMAN
NC score	0.177297 (rank : 53)	θ value	0.0330416 (rank : 55)
Query Neighborhood Hits	125	Target Neighborhood Hits	153	Shared Neighborhood Hits	33
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RFFL_HUMAN
NC score	0.174657 (rank : 54)	θ value	0.0563607 (rank : 57)
Query Neighborhood Hits	125	Target Neighborhood Hits	175	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

FARP2_HUMAN
NC score	0.140941 (rank : 55)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	125	Target Neighborhood Hits	240	Shared Neighborhood Hits	18
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_MOUSE
NC score	0.139686 (rank : 56)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	125	Target Neighborhood Hits	209	Shared Neighborhood Hits	16
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

PREX1_HUMAN
NC score	0.138099 (rank : 57)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	125	Target Neighborhood Hits	177	Shared Neighborhood Hits	19
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

FARP1_HUMAN
NC score	0.136383 (rank : 58)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	125	Target Neighborhood Hits	241	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

ECT2_MOUSE
NC score	0.132545 (rank : 59)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	125	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ECT2_HUMAN
NC score	0.129160 (rank : 60)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	125	Target Neighborhood Hits	98	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

RUFY3_MOUSE
NC score	0.117456 (rank : 61)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	125	Target Neighborhood Hits	579	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

RUFY3_HUMAN
NC score	0.116360 (rank : 62)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	125	Target Neighborhood Hits	594	Shared Neighborhood Hits	12
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

PKHG1_HUMAN
NC score	0.115853 (rank : 63)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	125	Target Neighborhood Hits	174	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

ARHG5_HUMAN
NC score	0.115256 (rank : 64)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	125	Target Neighborhood Hits	172	Shared Neighborhood Hits	13
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

ARHGA_MOUSE
NC score	0.109695 (rank : 65)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	125	Target Neighborhood Hits	125	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGA_HUMAN
NC score	0.108949 (rank : 66)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	125	Target Neighborhood Hits	187	Shared Neighborhood Hits	16
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

DSPP_HUMAN
NC score	0.106399 (rank : 67)	θ value	6.87365e-08 (rank : 37)
Query Neighborhood Hits	125	Target Neighborhood Hits	645	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

HAPIP_HUMAN
NC score	0.105517 (rank : 68)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	125	Target Neighborhood Hits	350	Shared Neighborhood Hits	20
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

NGEF_HUMAN
NC score	0.102749 (rank : 69)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	125	Target Neighborhood Hits	166	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

ARHGF_HUMAN
NC score	0.100205 (rank : 70)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	125	Target Neighborhood Hits	214	Shared Neighborhood Hits	13
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ARHGG_HUMAN
NC score	0.099910 (rank : 71)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	125	Target Neighborhood Hits	129	Shared Neighborhood Hits	13
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

NGEF_MOUSE
NC score	0.099775 (rank : 72)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	125	Target Neighborhood Hits	228	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

ARHG2_MOUSE
NC score	0.093870 (rank : 73)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	125	Target Neighborhood Hits	120	Shared Neighborhood Hits	14
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

DSPP_MOUSE
NC score	0.093249 (rank : 74)	θ value	0.00020696 (rank : 48)
Query Neighborhood Hits	125	Target Neighborhood Hits	491	Shared Neighborhood Hits	15
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

ARHGG_MOUSE
NC score	0.092554 (rank : 75)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	125	Target Neighborhood Hits	152	Shared Neighborhood Hits	13
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

MCF2L_MOUSE
NC score	0.091079 (rank : 76)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	125	Target Neighborhood Hits	255	Shared Neighborhood Hits	16
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

MCF2_HUMAN
NC score	0.090044 (rank : 77)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	125	Target Neighborhood Hits	166	Shared Neighborhood Hits	14
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

PKHG4_HUMAN
NC score	0.088461 (rank : 78)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	125	Target Neighborhood Hits	200	Shared Neighborhood Hits	12
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

LBC_HUMAN
NC score	0.086057 (rank : 79)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	125	Target Neighborhood Hits	90	Shared Neighborhood Hits	12
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

ARHG4_HUMAN
NC score	0.084947 (rank : 80)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	125	Target Neighborhood Hits	242	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG4_MOUSE
NC score	0.084254 (rank : 81)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	125	Target Neighborhood Hits	185	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

GNRP_HUMAN
NC score	0.084251 (rank : 82)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	125	Target Neighborhood Hits	239	Shared Neighborhood Hits	16
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

BCR_HUMAN
NC score	0.084035 (rank : 83)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	125	Target Neighborhood Hits	204	Shared Neighborhood Hits	12
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

GNRP_MOUSE
NC score	0.083740 (rank : 84)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	125	Target Neighborhood Hits	191	Shared Neighborhood Hits	13
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

ABR_HUMAN
NC score	0.082540 (rank : 85)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	125	Target Neighborhood Hits	166	Shared Neighborhood Hits	12
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

ARHG1_HUMAN
NC score	0.082165 (rank : 86)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	125	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

ARHG1_MOUSE
NC score	0.081413 (rank : 87)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	125	Target Neighborhood Hits	266	Shared Neighborhood Hits	14
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ARHG9_HUMAN
NC score	0.079060 (rank : 88)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	125	Target Neighborhood Hits	235	Shared Neighborhood Hits	12
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

CJ064_HUMAN
NC score	0.078945 (rank : 89)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	125	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZS81, Q8N4A3	Gene names	C10orf64
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf64.

ARHG9_MOUSE
NC score	0.077734 (rank : 90)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	125	Target Neighborhood Hits	234	Shared Neighborhood Hits	11
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

ARHG2_HUMAN
NC score	0.068471 (rank : 91)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	125	Target Neighborhood Hits	142	Shared Neighborhood Hits	12
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

ITSN1_MOUSE
NC score	0.067815 (rank : 92)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	125	Target Neighborhood Hits	1669	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN1_HUMAN
NC score	0.067752 (rank : 93)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	125	Target Neighborhood Hits	1757	Shared Neighborhood Hits	34
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN2_HUMAN
NC score	0.067523 (rank : 94)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	125	Target Neighborhood Hits	1173	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN2_MOUSE
NC score	0.067498 (rank : 95)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	125	Target Neighborhood Hits	1371	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

ARHGB_HUMAN
NC score	0.065621 (rank : 96)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	125	Target Neighborhood Hits	375	Shared Neighborhood Hits	14
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

TIAM1_HUMAN
NC score	0.065588 (rank : 97)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	125	Target Neighborhood Hits	225	Shared Neighborhood Hits	13
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

ARHGC_HUMAN
NC score	0.064810 (rank : 98)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	125	Target Neighborhood Hits	351	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
NC score	0.064012 (rank : 99)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	125	Target Neighborhood Hits	344	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

TIAM1_MOUSE
NC score	0.063631 (rank : 100)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	125	Target Neighborhood Hits	205	Shared Neighborhood Hits	13
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

ARHG7_HUMAN
NC score	0.063408 (rank : 101)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	125	Target Neighborhood Hits	347	Shared Neighborhood Hits	14
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

PKHA6_HUMAN
NC score	0.063277 (rank : 102)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	125	Target Neighborhood Hits	556	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
NC score	0.060560 (rank : 103)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	125	Target Neighborhood Hits	591	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

VAV_HUMAN
NC score	0.056854 (rank : 104)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	125	Target Neighborhood Hits	452	Shared Neighborhood Hits	14
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

NBEAL_HUMAN
NC score	0.055177 (rank : 105)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	125	Target Neighborhood Hits	200	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZS30, Q6Y876, Q6ZQY5, Q96Q30	Gene names	NBEAL1, ALS2CR17
Domain Architecture	No domain graphic available
Description	Neurobeachin-like 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein).

ARHG3_MOUSE
NC score	0.054645 (rank : 106)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	125	Target Neighborhood Hits	85	Shared Neighborhood Hits	9
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

VAV_MOUSE
NC score	0.054320 (rank : 107)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	125	Target Neighborhood Hits	430	Shared Neighborhood Hits	14
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

SWP70_HUMAN
NC score	0.053265 (rank : 108)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	125	Target Neighborhood Hits	973	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

ALS2_MOUSE
NC score	0.053169 (rank : 109)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	125	Target Neighborhood Hits	111	Shared Neighborhood Hits	13
SwissProt Accessions	Q920R0, Q8JZR1, Q9CXJ3	Gene names	Als2
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2 homolog).

ARHG8_HUMAN
NC score	0.053050 (rank : 110)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	125	Target Neighborhood Hits	85	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

VAV2_MOUSE
NC score	0.053040 (rank : 111)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	125	Target Neighborhood Hits	456	Shared Neighborhood Hits	16
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

ARHG3_HUMAN
NC score	0.052788 (rank : 112)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	125	Target Neighborhood Hits	82	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

ARHG7_MOUSE
NC score	0.052648 (rank : 113)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	125	Target Neighborhood Hits	396	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

VAV3_HUMAN
NC score	0.051964 (rank : 114)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	125	Target Neighborhood Hits	398	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
NC score	0.051291 (rank : 115)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	125	Target Neighborhood Hits	404	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

SWP70_MOUSE
NC score	0.050740 (rank : 116)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	125	Target Neighborhood Hits	1097	Shared Neighborhood Hits	33
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

WDR37_HUMAN
NC score	0.043672 (rank : 117)	θ value	0.0563607 (rank : 58)
Query Neighborhood Hits	125	Target Neighborhood Hits	303	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2I8, Q5SW03, Q9NTJ6	Gene names	WDR37, KIAA0982
Domain Architecture
Description	WD repeat protein 37.

WDR37_MOUSE
NC score	0.042458 (rank : 118)	θ value	0.0563607 (rank : 59)
Query Neighborhood Hits	125	Target Neighborhood Hits	298	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CBE3, Q80Y96, Q8CCL2	Gene names	Wdr37, Kiaa0982
Domain Architecture
Description	WD repeat protein 37.

GOGA4_HUMAN
NC score	0.037744 (rank : 119)	θ value	1.81305 (rank : 81)
Query Neighborhood Hits	125	Target Neighborhood Hits	2034	Shared Neighborhood Hits	27
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

CEP35_HUMAN
NC score	0.037518 (rank : 120)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	125	Target Neighborhood Hits	811	Shared Neighborhood Hits	19
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

AIM1_HUMAN
NC score	0.037478 (rank : 121)	θ value	0.0961366 (rank : 61)
Query Neighborhood Hits	125	Target Neighborhood Hits	247	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

IMA5_HUMAN
NC score	0.036438 (rank : 122)	θ value	0.365318 (rank : 65)
Query Neighborhood Hits	125	Target Neighborhood Hits	68	Shared Neighborhood Hits	6
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

IMA1_HUMAN
NC score	0.035505 (rank : 123)	θ value	0.813845 (rank : 68)
Query Neighborhood Hits	125	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	P52294, Q9BQ56	Gene names	KPNA1, RCH2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (NPI-1).

NEB1_HUMAN
NC score	0.035261 (rank : 124)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	125	Target Neighborhood Hits	829	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

SYCP1_HUMAN
NC score	0.035018 (rank : 125)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	125	Target Neighborhood Hits	1313	Shared Neighborhood Hits	19
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

IMA1_MOUSE
NC score	0.034338 (rank : 126)	θ value	1.38821 (rank : 74)
Query Neighborhood Hits	125	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q60960, Q3TF32	Gene names	Kpna1, Rch2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (Importin alpha S1).

AFTIN_MOUSE
NC score	0.033877 (rank : 127)	θ value	2.36792 (rank : 87)
Query Neighborhood Hits	125	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	Q80WT5, Q5SSE6, Q99KJ1	Gene names	Aftph, Afth
Domain Architecture	No domain graphic available
Description	Aftiphilin.

IMA7_MOUSE
NC score	0.033854 (rank : 128)	θ value	1.38821 (rank : 75)
Query Neighborhood Hits	125	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	O35345, Q9CVP9	Gene names	Kpna6, Kpna5
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6 subunit) (Importin alpha S2).

CEP57_MOUSE
NC score	0.033514 (rank : 129)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	125	Target Neighborhood Hits	580	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

IMA7_HUMAN
NC score	0.033264 (rank : 130)	θ value	1.81305 (rank : 82)
Query Neighborhood Hits	125	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	O60684	Gene names	KPNA6, IPOA7
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6).

GFRA2_MOUSE
NC score	0.032807 (rank : 131)	θ value	0.163984 (rank : 62)
Query Neighborhood Hits	125	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	O08842	Gene names	Gfra2, Gdnfrb, Trnr2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta).

BIN1_MOUSE
NC score	0.032009 (rank : 132)	θ value	0.0736092 (rank : 60)
Query Neighborhood Hits	125	Target Neighborhood Hits	283	Shared Neighborhood Hits	3
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

MYST4_HUMAN
NC score	0.031062 (rank : 133)	θ value	0.0252991 (rank : 54)
Query Neighborhood Hits	125	Target Neighborhood Hits	671	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

NU153_HUMAN
NC score	0.030215 (rank : 134)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	125	Target Neighborhood Hits	227	Shared Neighborhood Hits	13
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

SDPR_HUMAN
NC score	0.026276 (rank : 135)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	125	Target Neighborhood Hits	337	Shared Neighborhood Hits	14
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

GFRA2_HUMAN
NC score	0.023930 (rank : 136)	θ value	3.0926 (rank : 93)
Query Neighborhood Hits	125	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	O00451, O15316, O15328, Q7Z5C2	Gene names	GFRA2, GDNFRB, RETL2, TRNR2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta) (RET ligand 2).

PODXL_HUMAN
NC score	0.023732 (rank : 137)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	125	Target Neighborhood Hits	191	Shared Neighborhood Hits	5
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

SAS10_HUMAN
NC score	0.023112 (rank : 138)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	125	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQZ2, Q6FI82	Gene names	CRLZ1, SAS10
Domain Architecture	No domain graphic available
Description	Something about silencing protein 10 (Disrupter of silencing SAS10) (Charged amino acid-rich leucine zipper 1).

CND2_HUMAN
NC score	0.022077 (rank : 139)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	125	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q15003, Q8TB87	Gene names	NCAPH, BRRN, BRRN1, CAPH, KIAA0074
Domain Architecture
Description	Condensin complex subunit 2 (Non-SMC condensin I complex subunit H) (Barren homolog protein 1) (Chromosome-associated protein H) (hCAP-H) (XCAP-H homolog).

MUC13_HUMAN
NC score	0.021589 (rank : 140)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	125	Target Neighborhood Hits	164	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

DMRT1_MOUSE
NC score	0.021523 (rank : 141)	θ value	1.81305 (rank : 79)
Query Neighborhood Hits	125	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZ59, Q9QZ37, Q9QZA4	Gene names	Dmrt1
Domain Architecture
Description	Doublesex- and mab-3-related transcription factor 1.

CND2_MOUSE
NC score	0.021074 (rank : 142)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	125	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C156, Q8BY01, Q8VDM9	Gene names	Ncaph, Brrn, Brrn1, Caph
Domain Architecture
Description	Condensin complex subunit 2 (Non-SMC condensin I complex subunit H) (Barren homolog protein 1) (Chromosome-associated protein H) (mCAP-H) (XCAP-H homolog).

ANR12_HUMAN
NC score	0.020558 (rank : 143)	θ value	2.36792 (rank : 88)
Query Neighborhood Hits	125	Target Neighborhood Hits	1081	Shared Neighborhood Hits	17
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

T2FA_HUMAN
NC score	0.019714 (rank : 144)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	125	Target Neighborhood Hits	228	Shared Neighborhood Hits	9
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

K2027_HUMAN
NC score	0.019032 (rank : 145)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	125	Target Neighborhood Hits	194	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

RFIP1_MOUSE
NC score	0.018946 (rank : 146)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	125	Target Neighborhood Hits	152	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

TP53B_MOUSE
NC score	0.018639 (rank : 147)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	125	Target Neighborhood Hits	644	Shared Neighborhood Hits	14
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

SCAR3_HUMAN
NC score	0.017501 (rank : 148)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	125	Target Neighborhood Hits	205	Shared Neighborhood Hits	5
SwissProt Accessions	Q6AZY7, Q9UM15, Q9UM16	Gene names	SCARA3, CSR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class A member 3 (Cellular stress response gene protein).

TP53B_HUMAN
NC score	0.017230 (rank : 149)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	125	Target Neighborhood Hits	413	Shared Neighborhood Hits	12
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

CC14A_HUMAN
NC score	0.016739 (rank : 150)	θ value	1.38821 (rank : 73)
Query Neighborhood Hits	125	Target Neighborhood Hits	133	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

SAFB1_HUMAN
NC score	0.016166 (rank : 151)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	125	Target Neighborhood Hits	493	Shared Neighborhood Hits	9
SwissProt Accessions	Q15424, O60406, Q59HH8	Gene names	SAFB, HAP, HET, SAFB1
Domain Architecture
Description	Scaffold attachment factor B (Scaffold attachment factor B1) (SAF-B) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE- TATA-binding protein).

EAF2_HUMAN
NC score	0.013667 (rank : 152)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	125	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q96CJ1, Q9NZ82	Gene names	EAF2, TRAITS
Domain Architecture	No domain graphic available
Description	ELL-associated factor 2 (Testosterone-regulated apoptosis inducer and tumor suppressor protein).

DLG7_HUMAN
NC score	0.012374 (rank : 153)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	125	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q15398, Q8NG58	Gene names	DLG7, KIAA0008
Domain Architecture
Description	Discs large homolog 7 (Hepatoma up-regulated protein) (HURP).

CAC1H_HUMAN
NC score	0.012086 (rank : 154)	θ value	0.47712 (rank : 67)
Query Neighborhood Hits	125	Target Neighborhood Hits	307	Shared Neighborhood Hits	4
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

DCR1A_HUMAN
NC score	0.011607 (rank : 155)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	125	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PJP8, Q14701, Q6P5Y3, Q6PKL4	Gene names	DCLRE1A, KIAA0086, SNM1, SNM1A
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein (hSNM1) (hSNM1A).

ARID2_HUMAN
NC score	0.011502 (rank : 156)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	125	Target Neighborhood Hits	302	Shared Neighborhood Hits	6
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

ZN295_HUMAN
NC score	0.011464 (rank : 157)	θ value	0.21417 (rank : 63)
Query Neighborhood Hits	125	Target Neighborhood Hits	847	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ULJ3, Q6P4R0	Gene names	ZNF295, KIAA1227, ZBTB21
Domain Architecture
Description	Zinc finger protein 295 (Zinc finger and BTB domain-containing protein 21).

DGKG_HUMAN
NC score	0.010160 (rank : 158)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	125	Target Neighborhood Hits	171	Shared Neighborhood Hits	3
SwissProt Accessions	P49619	Gene names	DGKG, DAGK3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma).

SMYD5_MOUSE
NC score	0.009089 (rank : 159)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	125	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q3TYX3, Q3TRB2, Q91YL6	Gene names	Smyd5
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 5 (Protein NN8-4AG).

AFAD_HUMAN
NC score	0.008995 (rank : 160)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	125	Target Neighborhood Hits	689	Shared Neighborhood Hits	9
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

CP4AC_MOUSE
NC score	0.008898 (rank : 161)	θ value	0.365318 (rank : 64)
Query Neighborhood Hits	125	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	Q91WL5, Q3UNE4, Q6P931, Q8N7N3	Gene names	Cyp4a12
Domain Architecture	No domain graphic available
Description	Cytochrome P450 4A12 (EC 1.14.14.1) (CYPIVA12).

DGKG_MOUSE
NC score	0.008839 (rank : 162)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	125	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WG7	Gene names	Dgkg, Dagk3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma) (88 kDa diacylglycerol kinase).

RBP2_MOUSE
NC score	0.007807 (rank : 163)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	125	Target Neighborhood Hits	232	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

TRI37_MOUSE
NC score	0.007467 (rank : 164)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	125	Target Neighborhood Hits	316	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

WEE1B_HUMAN
NC score	0.007057 (rank : 165)	θ value	0.365318 (rank : 66)
Query Neighborhood Hits	125	Target Neighborhood Hits	836	Shared Neighborhood Hits	4
SwissProt Accessions	P0C1S8	Gene names	WEE1B, WEE2
Domain Architecture	No domain graphic available
Description	Wee1-like protein kinase 1B (EC 2.7.10.2) (Wee1B kinase).

FINC_MOUSE
NC score	0.007041 (rank : 166)	θ value	1.81305 (rank : 80)
Query Neighborhood Hits	125	Target Neighborhood Hits	309	Shared Neighborhood Hits	4
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

ZO3_HUMAN
NC score	0.006627 (rank : 167)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	125	Target Neighborhood Hits	219	Shared Neighborhood Hits	5
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

ZAN_HUMAN
NC score	0.006147 (rank : 168)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	125	Target Neighborhood Hits	679	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

SP2_HUMAN
NC score	0.005567 (rank : 169)	θ value	0.813845 (rank : 69)
Query Neighborhood Hits	125	Target Neighborhood Hits	747	Shared Neighborhood Hits	14
SwissProt Accessions	Q02086	Gene names	SP2, KIAA0048
Domain Architecture
Description	Transcription factor Sp2.

MAGBI_HUMAN
NC score	0.005141 (rank : 170)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	125	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q96M61	Gene names	MAGEB18
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen B18 (MAGE-B18 antigen).

WEE1B_MOUSE
NC score	0.004674 (rank : 171)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	125	Target Neighborhood Hits	765	Shared Neighborhood Hits	3
SwissProt Accessions	Q66JT0, Q4U4S4, Q7TPV9	Gene names	Wee1b, Wee2
Domain Architecture	No domain graphic available
Description	Wee1-like protein kinase 1B (EC 2.7.10.2) (Wee1B kinase) (mWee1B).

CNTP3_HUMAN
NC score	0.003569 (rank : 172)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	125	Target Neighborhood Hits	195	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

NR1H2_MOUSE
NC score	0.002197 (rank : 173)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	125	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	Q60644	Gene names	Nr1h2, Lxrb, Rip15, Unr, Unr2
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Retinoid X receptor-interacting protein No.15).

PO2F1_HUMAN
NC score	0.001854 (rank : 174)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	125	Target Neighborhood Hits	426	Shared Neighborhood Hits	4
SwissProt Accessions	P14859, Q5TBT7, Q6PK46, Q8NEU9, Q9BPV1	Gene names	POU2F1, OCT1, OTF1
Domain Architecture
Description	POU domain, class 2, transcription factor 1 (Octamer-binding transcription factor 1) (Oct-1) (OTF-1) (NF-A1).

MAZ_HUMAN
NC score	0.001470 (rank : 175)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	125	Target Neighborhood Hits	757	Shared Neighborhood Hits	14
SwissProt Accessions	P56270, Q15703, Q99443	Gene names	MAZ
Domain Architecture	No domain graphic available
Description	Myc-associated zinc finger protein (MAZI) (Purine-binding transcription factor) (Pur-1) (ZF87) (ZIF87).

MAZ_MOUSE
NC score	0.001432 (rank : 176)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	125	Target Neighborhood Hits	745	Shared Neighborhood Hits	14
SwissProt Accessions	P56671, Q9R1W0	Gene names	Maz
Domain Architecture	No domain graphic available
Description	Myc-associated zinc finger protein (MAZI) (Purine-binding transcription factor) (Pur-1).

ZN408_HUMAN
NC score	0.001415 (rank : 177)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	125	Target Neighborhood Hits	775	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H9D4	Gene names	ZNF408, PFM14, PRDM17
Domain Architecture	No domain graphic available
Description	Zinc finger protein 408 (PR-domain zinc finger protein 17).

ZFY1_MOUSE
NC score	0.001067 (rank : 178)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	125	Target Neighborhood Hits	790	Shared Neighborhood Hits	17
SwissProt Accessions	P10925	Gene names	Zfy1, Zfy-1
Domain Architecture
Description	Zinc finger Y-chromosomal protein 1.

ZN230_HUMAN
NC score	0.001034 (rank : 179)	θ value	1.06291 (rank : 72)
Query Neighborhood Hits	125	Target Neighborhood Hits	750	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UIE0, O15322, Q9P1U6	Gene names	ZNF230, FDZF2
Domain Architecture
Description	Zinc finger protein 230 (Zinc finger protein FDZF2).

PCD12_HUMAN
NC score	0.000995 (rank : 180)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	125	Target Neighborhood Hits	203	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NPG4, Q6UXB6, Q96KB8, Q9H7Y6, Q9H8E0	Gene names	PCDH12
Domain Architecture
Description	Protocadherin-12 precursor (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cadherin-2) (VE-cad-2).

VEZF1_HUMAN
NC score	0.000980 (rank : 181)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	125	Target Neighborhood Hits	744	Shared Neighborhood Hits	13
SwissProt Accessions	Q14119	Gene names	VEZF1, DB1, ZNF161
Domain Architecture	No domain graphic available
Description	Vascular endothelial zinc finger 1 (Zinc finger protein 161) (Putative transcription factor DB1).

ZN699_HUMAN
NC score	0.000932 (rank : 182)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	125	Target Neighborhood Hits	773	Shared Neighborhood Hits	21
SwissProt Accessions	Q32M78, Q8N9A1	Gene names	ZNF699
Domain Architecture	No domain graphic available
Description	Zinc finger protein 699 (Hangover homolog).

ZN317_HUMAN
NC score	0.000869 (rank : 183)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	125	Target Neighborhood Hits	759	Shared Neighborhood Hits	17
SwissProt Accessions	Q96PQ6, Q96PM0, Q96PM1, Q96PT2	Gene names	ZNF317
Domain Architecture
Description	Zinc finger protein 317.

ZN555_HUMAN
NC score	-0.000154 (rank : 184)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	125	Target Neighborhood Hits	741	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NEP9, Q8NA46, Q96MP1	Gene names	ZNF555
Domain Architecture	No domain graphic available
Description	Zinc finger protein 555.

CUBN_HUMAN
NC score	-0.000156 (rank : 185)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	125	Target Neighborhood Hits	482	Shared Neighborhood Hits	5
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).