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Network neighborhood for query Sequence : MTMR3_HUMAN

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MTMR3_HUMAN
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MTMR3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	163	Target Neighborhood Hits	163	Shared Neighborhood Hits	163
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

MTMR3_MOUSE
θ value	0 (rank : 2)	NC score	0.881126 (rank : 2)
Query Neighborhood Hits	163	Target Neighborhood Hits	78	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K296	Gene names	Mtmr3
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48).

MTMR2_HUMAN
θ value	2.30293e-96 (rank : 3)	NC score	0.836185 (rank : 4)
Query Neighborhood Hits	163	Target Neighborhood Hits	29	Shared Neighborhood Hits	15
SwissProt Accessions	Q13614, Q9UPS9	Gene names	MTMR2, KIAA1073
Domain Architecture
Description	Myotubularin-related protein 2 (EC 3.1.3.-).

MTMR2_MOUSE
θ value	1.14293e-95 (rank : 4)	NC score	0.836262 (rank : 3)
Query Neighborhood Hits	163	Target Neighborhood Hits	29	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z2D1, Q8VHA7	Gene names	Mtmr2
Domain Architecture
Description	Myotubularin-related protein 2 (EC 3.1.3.-).

MTM1_HUMAN
θ value	1.00126e-91 (rank : 5)	NC score	0.835353 (rank : 5)
Query Neighborhood Hits	163	Target Neighborhood Hits	32	Shared Neighborhood Hits	16
SwissProt Accessions	Q13496, Q8NEL1	Gene names	MTM1, CG2
Domain Architecture
Description	Myotubularin (EC 3.1.3.48).

MTM1_MOUSE
θ value	4.96919e-91 (rank : 6)	NC score	0.834850 (rank : 6)
Query Neighborhood Hits	163	Target Neighborhood Hits	36	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z2C5	Gene names	Mtm1
Domain Architecture
Description	Myotubularin (EC 3.1.3.48).

MTMR1_HUMAN
θ value	2.82168e-86 (rank : 7)	NC score	0.831974 (rank : 7)
Query Neighborhood Hits	163	Target Neighborhood Hits	28	Shared Neighborhood Hits	15
SwissProt Accessions	Q13613, Q9UBX6, Q9UEM0, Q9UQD5	Gene names	MTMR1
Domain Architecture
Description	Myotubularin-related protein 1 (EC 3.1.3.-).

MTMR1_MOUSE
θ value	3.11973e-85 (rank : 8)	NC score	0.831718 (rank : 8)
Query Neighborhood Hits	163	Target Neighborhood Hits	23	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z2C4	Gene names	Mtmr1
Domain Architecture
Description	Myotubularin-related protein 1 (EC 3.1.3.-).

MTMR7_HUMAN
θ value	1.71583e-75 (rank : 9)	NC score	0.824098 (rank : 11)
Query Neighborhood Hits	163	Target Neighborhood Hits	71	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y216, Q68DX4	Gene names	MTMR7
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

MTMR7_MOUSE
θ value	1.45253e-74 (rank : 10)	NC score	0.822706 (rank : 13)
Query Neighborhood Hits	163	Target Neighborhood Hits	81	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z2C9, Q8C4J6	Gene names	Mtmr7
Domain Architecture
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

MTMR6_HUMAN
θ value	3.34864e-71 (rank : 11)	NC score	0.828540 (rank : 9)
Query Neighborhood Hits	163	Target Neighborhood Hits	39	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y217, Q86TB7, Q86YH4, Q96P80	Gene names	MTMR6
Domain Architecture
Description	Myotubularin-related protein 6 (EC 3.1.3.-).

MTMR9_HUMAN
θ value	2.56992e-63 (rank : 12)	NC score	0.824059 (rank : 12)
Query Neighborhood Hits	163	Target Neighborhood Hits	16	Shared Neighborhood Hits	15
SwissProt Accessions	Q96QG7, Q52LU3, Q8WW11, Q96QG6, Q9NX50	Gene names	MTMR9, C8orf9, MTMR8
Domain Architecture
Description	Myotubularin-related protein 9.

MTMR9_MOUSE
θ value	2.56992e-63 (rank : 13)	NC score	0.824258 (rank : 10)
Query Neighborhood Hits	163	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z2D0, Q80XL4	Gene names	Mtmr9, Mtmr3
Domain Architecture
Description	Myotubularin-related protein 9.

MTMRD_HUMAN
θ value	1.12253e-42 (rank : 14)	NC score	0.638989 (rank : 15)
Query Neighborhood Hits	163	Target Neighborhood Hits	135	Shared Neighborhood Hits	21
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

MTMR5_HUMAN
θ value	1.05066e-40 (rank : 15)	NC score	0.640529 (rank : 14)
Query Neighborhood Hits	163	Target Neighborhood Hits	141	Shared Neighborhood Hits	18
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

RUFY1_HUMAN
θ value	6.85773e-16 (rank : 16)	NC score	0.265082 (rank : 45)
Query Neighborhood Hits	163	Target Neighborhood Hits	848	Shared Neighborhood Hits	63
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

RUFY1_MOUSE
θ value	8.95645e-16 (rank : 17)	NC score	0.274404 (rank : 42)
Query Neighborhood Hits	163	Target Neighborhood Hits	765	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

RUFY2_HUMAN
θ value	1.68911e-14 (rank : 18)	NC score	0.209850 (rank : 57)
Query Neighborhood Hits	163	Target Neighborhood Hits	1208	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

RUFY2_MOUSE
θ value	1.68911e-14 (rank : 19)	NC score	0.264718 (rank : 46)
Query Neighborhood Hits	163	Target Neighborhood Hits	820	Shared Neighborhood Hits	63
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

ZFY21_MOUSE
θ value	3.18553e-13 (rank : 20)	NC score	0.460339 (rank : 16)
Query Neighborhood Hits	163	Target Neighborhood Hits	72	Shared Neighborhood Hits	54
SwissProt Accessions	Q8VCM3, Q9D1E2	Gene names	Zfyve21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY28_HUMAN
θ value	3.18553e-13 (rank : 21)	NC score	0.447706 (rank : 18)
Query Neighborhood Hits	163	Target Neighborhood Hits	152	Shared Neighborhood Hits	55
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

ZFY21_HUMAN
θ value	1.2105e-12 (rank : 22)	NC score	0.458877 (rank : 17)
Query Neighborhood Hits	163	Target Neighborhood Hits	72	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BQ24, Q86T05, Q96LT1	Gene names	ZFYVE21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY16_MOUSE
θ value	1.33837e-11 (rank : 23)	NC score	0.395152 (rank : 22)
Query Neighborhood Hits	163	Target Neighborhood Hits	108	Shared Neighborhood Hits	55
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

EEA1_HUMAN
θ value	2.28291e-11 (rank : 24)	NC score	0.140036 (rank : 64)
Query Neighborhood Hits	163	Target Neighborhood Hits	1796	Shared Neighborhood Hits	80
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

FYV1_HUMAN
θ value	2.98157e-11 (rank : 25)	NC score	0.331786 (rank : 29)
Query Neighborhood Hits	163	Target Neighborhood Hits	217	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

FYV1_MOUSE
θ value	2.98157e-11 (rank : 26)	NC score	0.332048 (rank : 28)
Query Neighborhood Hits	163	Target Neighborhood Hits	191	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

ZFY16_HUMAN
θ value	3.89403e-11 (rank : 27)	NC score	0.389122 (rank : 25)
Query Neighborhood Hits	163	Target Neighborhood Hits	125	Shared Neighborhood Hits	54
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

EEA1_MOUSE
θ value	6.64225e-11 (rank : 28)	NC score	0.151436 (rank : 63)
Query Neighborhood Hits	163	Target Neighborhood Hits	1637	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

ZFYV1_HUMAN
θ value	1.47974e-10 (rank : 29)	NC score	0.378887 (rank : 26)
Query Neighborhood Hits	163	Target Neighborhood Hits	166	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

ZFYV9_HUMAN
θ value	1.47974e-10 (rank : 30)	NC score	0.398026 (rank : 21)
Query Neighborhood Hits	163	Target Neighborhood Hits	134	Shared Neighborhood Hits	55
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

FGD6_HUMAN
θ value	1.9326e-10 (rank : 31)	NC score	0.315922 (rank : 32)
Query Neighborhood Hits	163	Target Neighborhood Hits	237	Shared Neighborhood Hits	52
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

WDFY3_HUMAN
θ value	2.52405e-10 (rank : 32)	NC score	0.248968 (rank : 50)
Query Neighborhood Hits	163	Target Neighborhood Hits	348	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

WDFY3_MOUSE
θ value	2.52405e-10 (rank : 33)	NC score	0.249676 (rank : 49)
Query Neighborhood Hits	163	Target Neighborhood Hits	332	Shared Neighborhood Hits	57
SwissProt Accessions	Q6VNB8, Q8C8H7	Gene names	Wdfy3
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1).

FYCO1_HUMAN
θ value	4.30538e-10 (rank : 34)	NC score	0.173450 (rank : 59)
Query Neighborhood Hits	163	Target Neighborhood Hits	1149	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

ZFYV1_MOUSE
θ value	7.34386e-10 (rank : 35)	NC score	0.375909 (rank : 27)
Query Neighborhood Hits	163	Target Neighborhood Hits	153	Shared Neighborhood Hits	55
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

ANFY1_HUMAN
θ value	9.59137e-10 (rank : 36)	NC score	0.170214 (rank : 61)
Query Neighborhood Hits	163	Target Neighborhood Hits	480	Shared Neighborhood Hits	54
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

FGD6_MOUSE
θ value	9.59137e-10 (rank : 37)	NC score	0.307662 (rank : 35)
Query Neighborhood Hits	163	Target Neighborhood Hits	282	Shared Neighborhood Hits	55
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

ANFY1_MOUSE
θ value	1.25267e-09 (rank : 38)	NC score	0.171052 (rank : 60)
Query Neighborhood Hits	163	Target Neighborhood Hits	480	Shared Neighborhood Hits	56
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

PKHF2_HUMAN
θ value	2.13673e-09 (rank : 39)	NC score	0.402435 (rank : 20)
Query Neighborhood Hits	163	Target Neighborhood Hits	75	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

PKHF2_MOUSE
θ value	2.13673e-09 (rank : 40)	NC score	0.402971 (rank : 19)
Query Neighborhood Hits	163	Target Neighborhood Hits	77	Shared Neighborhood Hits	48
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

HGS_MOUSE
θ value	1.80886e-08 (rank : 41)	NC score	0.325274 (rank : 31)
Query Neighborhood Hits	163	Target Neighborhood Hits	589	Shared Neighborhood Hits	65
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HGS_HUMAN
θ value	2.36244e-08 (rank : 42)	NC score	0.326597 (rank : 30)
Query Neighborhood Hits	163	Target Neighborhood Hits	517	Shared Neighborhood Hits	64
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

FYCO1_MOUSE
θ value	5.26297e-08 (rank : 43)	NC score	0.163517 (rank : 62)
Query Neighborhood Hits	163	Target Neighborhood Hits	1059	Shared Neighborhood Hits	63
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

PKHF1_HUMAN
θ value	3.41135e-07 (rank : 44)	NC score	0.394109 (rank : 23)
Query Neighborhood Hits	163	Target Neighborhood Hits	76	Shared Neighborhood Hits	50
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

FGD2_MOUSE
θ value	4.45536e-07 (rank : 45)	NC score	0.270512 (rank : 43)
Query Neighborhood Hits	163	Target Neighborhood Hits	163	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

PKHF1_MOUSE
θ value	7.59969e-07 (rank : 46)	NC score	0.389431 (rank : 24)
Query Neighborhood Hits	163	Target Neighborhood Hits	80	Shared Neighborhood Hits	50
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

ZFY27_HUMAN
θ value	1.29631e-06 (rank : 47)	NC score	0.287738 (rank : 37)
Query Neighborhood Hits	163	Target Neighborhood Hits	64	Shared Neighborhood Hits	45
SwissProt Accessions	Q5T4F4, Q5T4F1, Q5T4F2, Q5T4F3, Q8N1K0, Q8N6D6, Q8NCA0, Q8NDE4, Q96M08	Gene names	ZFYVE27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

FGD4_HUMAN
θ value	2.88788e-06 (rank : 48)	NC score	0.254779 (rank : 47)
Query Neighborhood Hits	163	Target Neighborhood Hits	219	Shared Neighborhood Hits	49
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

ZFY27_MOUSE
θ value	2.88788e-06 (rank : 49)	NC score	0.285604 (rank : 39)
Query Neighborhood Hits	163	Target Neighborhood Hits	53	Shared Neighborhood Hits	45
SwissProt Accessions	Q3TXX3, Q8CFP8	Gene names	Zfyve27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

FGD2_HUMAN
θ value	4.92598e-06 (rank : 50)	NC score	0.269065 (rank : 44)
Query Neighborhood Hits	163	Target Neighborhood Hits	151	Shared Neighborhood Hits	52
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

FGD4_MOUSE
θ value	1.43324e-05 (rank : 51)	NC score	0.253284 (rank : 48)
Query Neighborhood Hits	163	Target Neighborhood Hits	227	Shared Neighborhood Hits	50
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

ZFY19_HUMAN
θ value	1.43324e-05 (rank : 52)	NC score	0.310530 (rank : 33)
Query Neighborhood Hits	163	Target Neighborhood Hits	206	Shared Neighborhood Hits	54
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

WDFY1_HUMAN
θ value	2.44474e-05 (rank : 53)	NC score	0.238336 (rank : 53)
Query Neighborhood Hits	163	Target Neighborhood Hits	305	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IWB7, Q9H9D5, Q9P2B3	Gene names	WDFY1, KIAA1435, WDF1, ZFYVE17
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 1 (WD40- and FYVE domain- containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain-containing protein 17).

WDFY2_HUMAN
θ value	4.1701e-05 (rank : 54)	NC score	0.231928 (rank : 56)
Query Neighborhood Hits	163	Target Neighborhood Hits	332	Shared Neighborhood Hits	49
SwissProt Accessions	Q96P53, Q96CS1	Gene names	WDFY2, WDF2, ZFYVE22
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2) (Zinc finger FYVE domain-containing protein 22).

WDFY2_MOUSE
θ value	4.1701e-05 (rank : 55)	NC score	0.233942 (rank : 54)
Query Neighborhood Hits	163	Target Neighborhood Hits	337	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BUB4	Gene names	Wdfy2
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2).

ZFY19_MOUSE
θ value	5.44631e-05 (rank : 56)	NC score	0.309269 (rank : 34)
Query Neighborhood Hits	163	Target Neighborhood Hits	143	Shared Neighborhood Hits	52
SwissProt Accessions	Q9DAZ9, Q8VCV7	Gene names	Zfyve19
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19.

FGD3_HUMAN
θ value	0.000158464 (rank : 57)	NC score	0.233540 (rank : 55)
Query Neighborhood Hits	163	Target Neighborhood Hits	249	Shared Neighborhood Hits	55
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

FGD5_HUMAN
θ value	0.000270298 (rank : 58)	NC score	0.287148 (rank : 38)
Query Neighborhood Hits	163	Target Neighborhood Hits	235	Shared Neighborhood Hits	56
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

FGD5_MOUSE
θ value	0.00035302 (rank : 59)	NC score	0.293845 (rank : 36)
Query Neighborhood Hits	163	Target Neighborhood Hits	170	Shared Neighborhood Hits	56
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

FGD1_HUMAN
θ value	0.000786445 (rank : 60)	NC score	0.242349 (rank : 51)
Query Neighborhood Hits	163	Target Neighborhood Hits	367	Shared Neighborhood Hits	58
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

RBNS5_HUMAN
θ value	0.000786445 (rank : 61)	NC score	0.282042 (rank : 40)
Query Neighborhood Hits	163	Target Neighborhood Hits	242	Shared Neighborhood Hits	55
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

FGD1_MOUSE
θ value	0.00102713 (rank : 62)	NC score	0.241674 (rank : 52)
Query Neighborhood Hits	163	Target Neighborhood Hits	387	Shared Neighborhood Hits	57
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

RBNS5_MOUSE
θ value	0.00134147 (rank : 63)	NC score	0.277688 (rank : 41)
Query Neighborhood Hits	163	Target Neighborhood Hits	266	Shared Neighborhood Hits	51
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

PTN21_HUMAN
θ value	0.0431538 (rank : 64)	NC score	0.011479 (rank : 130)
Query Neighborhood Hits	163	Target Neighborhood Hits	143	Shared Neighborhood Hits	5
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

FGD3_MOUSE
θ value	0.0736092 (rank : 65)	NC score	0.205128 (rank : 58)
Query Neighborhood Hits	163	Target Neighborhood Hits	257	Shared Neighborhood Hits	53
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

IP3KC_HUMAN
θ value	0.0736092 (rank : 66)	NC score	0.026703 (rank : 97)
Query Neighborhood Hits	163	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q96DU7, Q9UE25, Q9Y475	Gene names	ITPKC, IP3KC
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase C) (InsP 3-kinase C) (IP3K-C).

MCPH1_HUMAN
θ value	0.163984 (rank : 67)	NC score	0.034800 (rank : 90)
Query Neighborhood Hits	163	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEM0, Q66GU1, Q9H9C7	Gene names	MCPH1
Domain Architecture
Description	Microcephalin.

CM007_MOUSE
θ value	0.21417 (rank : 68)	NC score	0.047456 (rank : 89)
Query Neighborhood Hits	163	Target Neighborhood Hits	416	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

SYNE1_HUMAN
θ value	0.279714 (rank : 69)	NC score	0.031681 (rank : 91)
Query Neighborhood Hits	163	Target Neighborhood Hits	1484	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

CO3A1_HUMAN
θ value	0.365318 (rank : 70)	NC score	0.007728 (rank : 146)
Query Neighborhood Hits	163	Target Neighborhood Hits	452	Shared Neighborhood Hits	12
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

ZN653_HUMAN
θ value	0.47712 (rank : 71)	NC score	-0.000496 (rank : 170)
Query Neighborhood Hits	163	Target Neighborhood Hits	719	Shared Neighborhood Hits	7
SwissProt Accessions	Q96CK0, Q96AS7	Gene names	ZNF653, ZIP67
Domain Architecture	No domain graphic available
Description	Zinc finger protein 653 (67 kDa zinc finger protein) (Zinc finger protein Zip67).

PIM1_HUMAN
θ value	0.62314 (rank : 72)	NC score	-0.000812 (rank : 172)
Query Neighborhood Hits	163	Target Neighborhood Hits	797	Shared Neighborhood Hits	7
SwissProt Accessions	P11309, Q38RT9, Q96RG3	Gene names	PIM1
Domain Architecture
Description	Proto-oncogene serine/threonine-protein kinase Pim-1 (EC 2.7.11.1).

RAF1_MOUSE
θ value	0.62314 (rank : 73)	NC score	0.001721 (rank : 168)
Query Neighborhood Hits	163	Target Neighborhood Hits	886	Shared Neighborhood Hits	11
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

CM007_HUMAN
θ value	0.813845 (rank : 74)	NC score	0.048551 (rank : 88)
Query Neighborhood Hits	163	Target Neighborhood Hits	422	Shared Neighborhood Hits	16
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

HEM1_MOUSE
θ value	0.813845 (rank : 75)	NC score	0.013613 (rank : 122)
Query Neighborhood Hits	163	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VC19, Q64453	Gene names	Alas1
Domain Architecture	No domain graphic available
Description	5-aminolevulinate synthase, nonspecific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-H).

TM108_MOUSE
θ value	0.813845 (rank : 76)	NC score	0.021025 (rank : 104)
Query Neighborhood Hits	163	Target Neighborhood Hits	336	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

ABI3_MOUSE
θ value	1.06291 (rank : 77)	NC score	0.016717 (rank : 112)
Query Neighborhood Hits	163	Target Neighborhood Hits	227	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

NUAK2_HUMAN
θ value	1.06291 (rank : 78)	NC score	-0.003022 (rank : 179)
Query Neighborhood Hits	163	Target Neighborhood Hits	874	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H093	Gene names	NUAK2
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (SNF1/AMP kinase-related kinase) (SNARK).

ZN313_HUMAN
θ value	1.06291 (rank : 79)	NC score	0.015845 (rank : 116)
Query Neighborhood Hits	163	Target Neighborhood Hits	264	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

ZN313_MOUSE
θ value	1.06291 (rank : 80)	NC score	0.015439 (rank : 117)
Query Neighborhood Hits	163	Target Neighborhood Hits	273	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

CJ118_MOUSE
θ value	1.38821 (rank : 81)	NC score	0.028761 (rank : 94)
Query Neighborhood Hits	163	Target Neighborhood Hits	1132	Shared Neighborhood Hits	28
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

DAAM2_MOUSE
θ value	1.38821 (rank : 82)	NC score	0.013920 (rank : 120)
Query Neighborhood Hits	163	Target Neighborhood Hits	371	Shared Neighborhood Hits	11
SwissProt Accessions	Q80U19, Q810J5	Gene names	Daam2, Kiaa0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

NKTR_HUMAN
θ value	1.38821 (rank : 83)	NC score	0.008059 (rank : 143)
Query Neighborhood Hits	163	Target Neighborhood Hits	658	Shared Neighborhood Hits	17
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

PA24E_MOUSE
θ value	1.38821 (rank : 84)	NC score	0.008663 (rank : 138)
Query Neighborhood Hits	163	Target Neighborhood Hits	95	Shared Neighborhood Hits	2
SwissProt Accessions	Q50L42, Q8BX44	Gene names	Pla2g4e
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

SMR1_MOUSE
θ value	1.38821 (rank : 85)	NC score	0.028085 (rank : 95)
Query Neighborhood Hits	163	Target Neighborhood Hits	103	Shared Neighborhood Hits	5
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

ABI3_HUMAN
θ value	1.81305 (rank : 86)	NC score	0.014551 (rank : 118)
Query Neighborhood Hits	163	Target Neighborhood Hits	227	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

CBP_HUMAN
θ value	1.81305 (rank : 87)	NC score	0.011771 (rank : 129)
Query Neighborhood Hits	163	Target Neighborhood Hits	941	Shared Neighborhood Hits	24
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CHFR_MOUSE
θ value	1.81305 (rank : 88)	NC score	0.013250 (rank : 124)
Query Neighborhood Hits	163	Target Neighborhood Hits	264	Shared Neighborhood Hits	10
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

PALM_HUMAN
θ value	1.81305 (rank : 89)	NC score	0.024268 (rank : 98)
Query Neighborhood Hits	163	Target Neighborhood Hits	136	Shared Neighborhood Hits	7
SwissProt Accessions	O75781, O43359, O95673, Q92559, Q9UPJ4, Q9UQS2, Q9UQS3	Gene names	PALM, KIAA0270
Domain Architecture
Description	Paralemmin.

PGBM_HUMAN
θ value	1.81305 (rank : 90)	NC score	-0.000608 (rank : 171)
Query Neighborhood Hits	163	Target Neighborhood Hits	1113	Shared Neighborhood Hits	13
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

RENT1_HUMAN
θ value	1.81305 (rank : 91)	NC score	0.016170 (rank : 113)
Query Neighborhood Hits	163	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

RENT1_MOUSE
θ value	1.81305 (rank : 92)	NC score	0.016142 (rank : 114)
Query Neighborhood Hits	163	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

RNF34_HUMAN
θ value	1.81305 (rank : 93)	NC score	0.091050 (rank : 68)
Query Neighborhood Hits	163	Target Neighborhood Hits	153	Shared Neighborhood Hits	34
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

TSKS_MOUSE
θ value	1.81305 (rank : 94)	NC score	0.017343 (rank : 110)
Query Neighborhood Hits	163	Target Neighborhood Hits	188	Shared Neighborhood Hits	8
SwissProt Accessions	O54887	Gene names	Stk22s1, Tsks
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

BC11B_MOUSE
θ value	2.36792 (rank : 95)	NC score	-0.001811 (rank : 174)
Query Neighborhood Hits	163	Target Neighborhood Hits	767	Shared Neighborhood Hits	10
SwissProt Accessions	Q99PV8, Q8C2I1, Q99PV6, Q99PV7, Q9JLF8	Gene names	Bcl11b, Ctip2, Rit1
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11B (B-cell CLL/lymphoma 11B) (Radiation- induced tumor suppressor gene 1 protein) (mRit1) (COUP-TF-interacting protein 2).

DDX21_MOUSE
θ value	2.36792 (rank : 96)	NC score	0.010290 (rank : 131)
Query Neighborhood Hits	163	Target Neighborhood Hits	350	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DZIP1_MOUSE
θ value	2.36792 (rank : 97)	NC score	0.023709 (rank : 100)
Query Neighborhood Hits	163	Target Neighborhood Hits	530	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BMD2, Q6ZQ10, Q9CRK5	Gene names	Dzip1, Kiaa0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog).

HIRP3_HUMAN
θ value	2.36792 (rank : 98)	NC score	0.018398 (rank : 109)
Query Neighborhood Hits	163	Target Neighborhood Hits	323	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

MUC2_HUMAN
θ value	2.36792 (rank : 99)	NC score	0.007006 (rank : 151)
Query Neighborhood Hits	163	Target Neighborhood Hits	906	Shared Neighborhood Hits	12
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

RFFL_HUMAN
θ value	2.36792 (rank : 100)	NC score	0.081132 (rank : 70)
Query Neighborhood Hits	163	Target Neighborhood Hits	175	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

TTC14_HUMAN
θ value	2.36792 (rank : 101)	NC score	0.022255 (rank : 102)
Query Neighborhood Hits	163	Target Neighborhood Hits	274	Shared Neighborhood Hits	9
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

AKA12_HUMAN
θ value	3.0926 (rank : 102)	NC score	0.016927 (rank : 111)
Query Neighborhood Hits	163	Target Neighborhood Hits	825	Shared Neighborhood Hits	19
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

CN044_HUMAN
θ value	3.0926 (rank : 103)	NC score	0.020352 (rank : 107)
Query Neighborhood Hits	163	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	Q96MY7	Gene names	C14orf44
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf44.

FHOD1_HUMAN
θ value	3.0926 (rank : 104)	NC score	0.011896 (rank : 127)
Query Neighborhood Hits	163	Target Neighborhood Hits	184	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

FINC_HUMAN
θ value	3.0926 (rank : 105)	NC score	0.004863 (rank : 157)
Query Neighborhood Hits	163	Target Neighborhood Hits	302	Shared Neighborhood Hits	7
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

KCNH2_HUMAN
θ value	3.0926 (rank : 106)	NC score	0.004243 (rank : 162)
Query Neighborhood Hits	163	Target Neighborhood Hits	158	Shared Neighborhood Hits	2
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

RNF34_MOUSE
θ value	3.0926 (rank : 107)	NC score	0.094047 (rank : 67)
Query Neighborhood Hits	163	Target Neighborhood Hits	160	Shared Neighborhood Hits	36
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RTN2_HUMAN
θ value	3.0926 (rank : 108)	NC score	0.012198 (rank : 125)
Query Neighborhood Hits	163	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	O75298, O60509, Q7RTM6, Q7RTN1, Q7RTN2	Gene names	RTN2, NSPL1
Domain Architecture
Description	Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (NSPLI).

RXINP_HUMAN
θ value	3.0926 (rank : 109)	NC score	0.013607 (rank : 123)
Query Neighborhood Hits	163	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q96RL1, Q5XKQ1, Q7Z3W7, Q8N5B9, Q9BZR1, Q9BZR5, Q9UHX7	Gene names	RXRIP110, RAP80
Domain Architecture	No domain graphic available
Description	Retinoid X receptor-interacting protein 110 (Receptor-associated protein 80) (Nuclear zinc finger protein RAP80).

STRC_MOUSE
θ value	3.0926 (rank : 110)	NC score	0.011797 (rank : 128)
Query Neighborhood Hits	163	Target Neighborhood Hits	89	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VIM6	Gene names	Strc
Domain Architecture	No domain graphic available
Description	Stereocilin precursor.

TNR6A_HUMAN
θ value	3.0926 (rank : 111)	NC score	0.014040 (rank : 119)
Query Neighborhood Hits	163	Target Neighborhood Hits	343	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

TSYL1_HUMAN
θ value	3.0926 (rank : 112)	NC score	0.009114 (rank : 133)
Query Neighborhood Hits	163	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H0U9, O75885	Gene names	TSPYL1, TSPYL
Domain Architecture
Description	Testis-specific Y-encoded-like protein 1 (TSPY-like 1).

CCD45_HUMAN
θ value	4.03905 (rank : 113)	NC score	0.022761 (rank : 101)
Query Neighborhood Hits	163	Target Neighborhood Hits	525	Shared Neighborhood Hits	16
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CENPJ_HUMAN
θ value	4.03905 (rank : 114)	NC score	0.020752 (rank : 106)
Query Neighborhood Hits	163	Target Neighborhood Hits	721	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

FBX42_HUMAN
θ value	4.03905 (rank : 115)	NC score	0.009017 (rank : 134)
Query Neighborhood Hits	163	Target Neighborhood Hits	121	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P3S6, Q5TEU8, Q86XI0, Q8N3N4, Q8N5F8, Q9BRM0, Q9P2L4	Gene names	FBXO42, FBX42, KIAA1332
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

FGL2_MOUSE
θ value	4.03905 (rank : 116)	NC score	0.008297 (rank : 140)
Query Neighborhood Hits	163	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	P12804	Gene names	Fgl2, Fiblp
Domain Architecture
Description	Fibroleukin precursor (Fibrinogen-like protein 2) (Prothrombinase) (Cytotoxic T-lymphocyte-specific protein).

IGHA1_HUMAN
θ value	4.03905 (rank : 117)	NC score	0.004833 (rank : 158)
Query Neighborhood Hits	163	Target Neighborhood Hits	194	Shared Neighborhood Hits	4
SwissProt Accessions	P01876	Gene names	IGHA1
Domain Architecture
Description	Ig alpha-1 chain C region.

MCPH1_MOUSE
θ value	4.03905 (rank : 118)	NC score	0.024091 (rank : 99)
Query Neighborhood Hits	163	Target Neighborhood Hits	116	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

MEF2C_HUMAN
θ value	4.03905 (rank : 119)	NC score	0.006875 (rank : 152)
Query Neighborhood Hits	163	Target Neighborhood Hits	90	Shared Neighborhood Hits	2
SwissProt Accessions	Q06413	Gene names	MEF2C
Domain Architecture
Description	Myocyte-specific enhancer factor 2C.

MUC5B_HUMAN
θ value	4.03905 (rank : 120)	NC score	0.007520 (rank : 147)
Query Neighborhood Hits	163	Target Neighborhood Hits	1020	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

PTPRV_MOUSE
θ value	4.03905 (rank : 121)	NC score	0.009862 (rank : 132)
Query Neighborhood Hits	163	Target Neighborhood Hits	179	Shared Neighborhood Hits	9
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

TRIPB_HUMAN
θ value	4.03905 (rank : 122)	NC score	0.030796 (rank : 93)
Query Neighborhood Hits	163	Target Neighborhood Hits	1587	Shared Neighborhood Hits	37
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

BCL9_HUMAN
θ value	5.27518 (rank : 123)	NC score	0.008947 (rank : 136)
Query Neighborhood Hits	163	Target Neighborhood Hits	1008	Shared Neighborhood Hits	22
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CROCC_HUMAN
θ value	5.27518 (rank : 124)	NC score	0.027802 (rank : 96)
Query Neighborhood Hits	163	Target Neighborhood Hits	1409	Shared Neighborhood Hits	32
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

LAMA5_HUMAN
θ value	5.27518 (rank : 125)	NC score	0.008435 (rank : 139)
Query Neighborhood Hits	163	Target Neighborhood Hits	976	Shared Neighborhood Hits	26
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LMO6_MOUSE
θ value	5.27518 (rank : 126)	NC score	0.002862 (rank : 165)
Query Neighborhood Hits	163	Target Neighborhood Hits	277	Shared Neighborhood Hits	5
SwissProt Accessions	Q80VL3, Q8CAY9	Gene names	Lmo6
Domain Architecture	No domain graphic available
Description	LIM domain only protein 6 (Triple LIM domain protein 6).

NOS3_MOUSE
θ value	5.27518 (rank : 127)	NC score	0.005147 (rank : 155)
Query Neighborhood Hits	163	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	P70313, O55056	Gene names	Nos3, Ecnos
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

PKNX1_HUMAN
θ value	5.27518 (rank : 128)	NC score	0.004466 (rank : 161)
Query Neighborhood Hits	163	Target Neighborhood Hits	101	Shared Neighborhood Hits	3
SwissProt Accessions	P55347, O00528, Q8IWT7	Gene names	PKNOX1, PREP1
Domain Architecture
Description	Homeobox protein PKNOX1 (PBX/knotted homeobox 1) (Homeobox protein PREP-1).

PTPRO_HUMAN
θ value	5.27518 (rank : 129)	NC score	0.007117 (rank : 150)
Query Neighborhood Hits	163	Target Neighborhood Hits	139	Shared Neighborhood Hits	6
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

RFFL_MOUSE
θ value	5.27518 (rank : 130)	NC score	0.085403 (rank : 69)
Query Neighborhood Hits	163	Target Neighborhood Hits	145	Shared Neighborhood Hits	37
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

TEX14_HUMAN
θ value	5.27518 (rank : 131)	NC score	0.004068 (rank : 163)
Query Neighborhood Hits	163	Target Neighborhood Hits	1103	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TRDN_HUMAN
θ value	5.27518 (rank : 132)	NC score	0.021930 (rank : 103)
Query Neighborhood Hits	163	Target Neighborhood Hits	542	Shared Neighborhood Hits	18
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

WWC1_MOUSE
θ value	5.27518 (rank : 133)	NC score	0.008046 (rank : 144)
Query Neighborhood Hits	163	Target Neighborhood Hits	290	Shared Neighborhood Hits	10
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

ZN646_HUMAN
θ value	5.27518 (rank : 134)	NC score	-0.002355 (rank : 177)
Query Neighborhood Hits	163	Target Neighborhood Hits	813	Shared Neighborhood Hits	13
SwissProt Accessions	O15015	Gene names	ZNF646, KIAA0296
Domain Architecture	No domain graphic available
Description	Zinc finger protein 646.

ZN653_MOUSE
θ value	5.27518 (rank : 135)	NC score	-0.001984 (rank : 175)
Query Neighborhood Hits	163	Target Neighborhood Hits	744	Shared Neighborhood Hits	7
SwissProt Accessions	Q6YND2, Q8BHT8, Q8CI02	Gene names	Znf653, Zfp653, Zip67
Domain Architecture	No domain graphic available
Description	Zinc finger protein 653 (67 kDa zinc finger protein) (Zinc finger protein Zip67).

A16L1_MOUSE
θ value	6.88961 (rank : 136)	NC score	0.020926 (rank : 105)
Query Neighborhood Hits	163	Target Neighborhood Hits	776	Shared Neighborhood Hits	22
SwissProt Accessions	Q8C0J2, Q6KAT7, Q80U97, Q80U98, Q80U99, Q80Y53, Q9DB63	Gene names	Atg16l1, Apg16l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

ANKS1_HUMAN
θ value	6.88961 (rank : 137)	NC score	0.007964 (rank : 145)
Query Neighborhood Hits	163	Target Neighborhood Hits	438	Shared Neighborhood Hits	6
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ASPM_MOUSE
θ value	6.88961 (rank : 138)	NC score	0.006011 (rank : 154)
Query Neighborhood Hits	163	Target Neighborhood Hits	150	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CJ27, O88482, Q8BJI8, Q8BKT4	Gene names	Aspm, Calmbp1, Sha1
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein homolog (Calmodulin-binding protein 1) (Spindle and hydroxyurea checkpoint abnormal protein) (Calmodulin-binding protein Sha1).

COIA1_HUMAN
θ value	6.88961 (rank : 139)	NC score	0.002788 (rank : 166)
Query Neighborhood Hits	163	Target Neighborhood Hits	447	Shared Neighborhood Hits	12
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

FLRT2_HUMAN
θ value	6.88961 (rank : 140)	NC score	-0.000813 (rank : 173)
Query Neighborhood Hits	163	Target Neighborhood Hits	295	Shared Neighborhood Hits	2
SwissProt Accessions	O43155	Gene names	FLRT2, KIAA0405
Domain Architecture
Description	Leucine-rich repeat transmembrane protein FLRT2 precursor (Fibronectin-like domain-containing leucine-rich transmembrane protein 2).

MLL4_HUMAN
θ value	6.88961 (rank : 141)	NC score	0.002933 (rank : 164)
Query Neighborhood Hits	163	Target Neighborhood Hits	722	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

NASP_HUMAN
θ value	6.88961 (rank : 142)	NC score	0.012159 (rank : 126)
Query Neighborhood Hits	163	Target Neighborhood Hits	709	Shared Neighborhood Hits	19
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

RAF1_HUMAN
θ value	6.88961 (rank : 143)	NC score	-0.002920 (rank : 178)
Query Neighborhood Hits	163	Target Neighborhood Hits	886	Shared Neighborhood Hits	10
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

SFPQ_HUMAN
θ value	6.88961 (rank : 144)	NC score	0.002769 (rank : 167)
Query Neighborhood Hits	163	Target Neighborhood Hits	986	Shared Neighborhood Hits	19
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SNX1_MOUSE
θ value	6.88961 (rank : 145)	NC score	0.004580 (rank : 160)
Query Neighborhood Hits	163	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WV80, Q9EQZ9	Gene names	Snx1
Domain Architecture
Description	Sorting nexin-1.

TBC14_HUMAN
θ value	6.88961 (rank : 146)	NC score	0.008291 (rank : 141)
Query Neighborhood Hits	163	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P2M4, Q8IW15	Gene names	TBC1D14, KIAA1322
Domain Architecture
Description	TBC1 domain family member 14.

TBC14_MOUSE
θ value	6.88961 (rank : 147)	NC score	0.008066 (rank : 142)
Query Neighborhood Hits	163	Target Neighborhood Hits	135	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CGA2, Q8CHA5	Gene names	Tbc1d14, D5Ertd110e, Kiaa1322
Domain Architecture
Description	TBC1 domain family member 14.

TRI44_MOUSE
θ value	6.88961 (rank : 148)	NC score	0.007460 (rank : 148)
Query Neighborhood Hits	163	Target Neighborhood Hits	327	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

WNK3_HUMAN
θ value	6.88961 (rank : 149)	NC score	-0.002241 (rank : 176)
Query Neighborhood Hits	163	Target Neighborhood Hits	948	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

CN044_MOUSE
θ value	8.99809 (rank : 150)	NC score	0.013867 (rank : 121)
Query Neighborhood Hits	163	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CB59, Q8BQX8, Q8BSL9, Q8CBZ3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf44 homolog.

DUS3_HUMAN
θ value	8.99809 (rank : 151)	NC score	0.004886 (rank : 156)
Query Neighborhood Hits	163	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	P51452	Gene names	DUSP3, VHR
Domain Architecture
Description	Dual specificity protein phosphatase 3 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase VHR).

INSM1_HUMAN
θ value	8.99809 (rank : 152)	NC score	0.000003 (rank : 169)
Query Neighborhood Hits	163	Target Neighborhood Hits	683	Shared Neighborhood Hits	11
SwissProt Accessions	Q01101	Gene names	INSM1, IA1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

KPCE_MOUSE
θ value	8.99809 (rank : 153)	NC score	-0.004237 (rank : 180)
Query Neighborhood Hits	163	Target Neighborhood Hits	906	Shared Neighborhood Hits	9
SwissProt Accessions	P16054	Gene names	Prkce, Pkce, Pkcea
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

MINT_MOUSE
θ value	8.99809 (rank : 154)	NC score	0.008906 (rank : 137)
Query Neighborhood Hits	163	Target Neighborhood Hits	1514	Shared Neighborhood Hits	34
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MRIP_MOUSE
θ value	8.99809 (rank : 155)	NC score	0.016026 (rank : 115)
Query Neighborhood Hits	163	Target Neighborhood Hits	569	Shared Neighborhood Hits	16
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

MYRIP_HUMAN
θ value	8.99809 (rank : 156)	NC score	0.019968 (rank : 108)
Query Neighborhood Hits	163	Target Neighborhood Hits	269	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

NIBA_HUMAN
θ value	8.99809 (rank : 157)	NC score	0.006532 (rank : 153)
Query Neighborhood Hits	163	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZQ8, Q5TEM8, Q8TEI5, Q9H593, Q9H9Y8, Q9HCB9	Gene names	C1orf24
Domain Architecture	No domain graphic available
Description	Niban protein.

NSBP1_MOUSE
θ value	8.99809 (rank : 158)	NC score	0.004829 (rank : 159)
Query Neighborhood Hits	163	Target Neighborhood Hits	681	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

RTN4_MOUSE
θ value	8.99809 (rank : 159)	NC score	0.008987 (rank : 135)
Query Neighborhood Hits	163	Target Neighborhood Hits	341	Shared Neighborhood Hits	8
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

SENP6_HUMAN
θ value	8.99809 (rank : 160)	NC score	0.007162 (rank : 149)
Query Neighborhood Hits	163	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZR1, O94891, Q8TBY4, Q9UJV5	Gene names	SENP6, KIAA0797, SSP1, SUSP1
Domain Architecture
Description	Sentrin-specific protease 6 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP6) (SUMO-1-specific protease 1).

SPAG5_HUMAN
θ value	8.99809 (rank : 161)	NC score	0.031315 (rank : 92)
Query Neighborhood Hits	163	Target Neighborhood Hits	625	Shared Neighborhood Hits	20
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

ZN490_HUMAN
θ value	8.99809 (rank : 162)	NC score	-0.004758 (rank : 182)
Query Neighborhood Hits	163	Target Neighborhood Hits	754	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ULM2	Gene names	ZNF490, KIAA1198
Domain Architecture
Description	Zinc finger protein 490.

ZN670_HUMAN
θ value	8.99809 (rank : 163)	NC score	-0.004552 (rank : 181)
Query Neighborhood Hits	163	Target Neighborhood Hits	736	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BS34	Gene names	ZNF670
Domain Architecture	No domain graphic available
Description	Zinc finger protein 670.

ARHG5_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.056316 (rank : 82)
Query Neighborhood Hits	163	Target Neighborhood Hits	172	Shared Neighborhood Hits	14
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

ARHGA_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.052955 (rank : 85)
Query Neighborhood Hits	163	Target Neighborhood Hits	187	Shared Neighborhood Hits	15
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGA_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.053795 (rank : 83)
Query Neighborhood Hits	163	Target Neighborhood Hits	125	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

CJ064_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.066050 (rank : 77)
Query Neighborhood Hits	163	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZS81, Q8N4A3	Gene names	C10orf64
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf64.

DEN4C_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.051309 (rank : 86)
Query Neighborhood Hits	163	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VZ89, Q6AI48, Q6ZUB3, Q8NCY7, Q9H6N4, Q9NUT1, Q9NWA5	Gene names	DENND4C, C9orf55
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 4C.

ECT2_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.063044 (rank : 79)
Query Neighborhood Hits	163	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ECT2_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.064539 (rank : 78)
Query Neighborhood Hits	163	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

FARP1_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.075897 (rank : 71)
Query Neighborhood Hits	163	Target Neighborhood Hits	241	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FARP2_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.074646 (rank : 72)
Query Neighborhood Hits	163	Target Neighborhood Hits	240	Shared Neighborhood Hits	19
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.073036 (rank : 73)
Query Neighborhood Hits	163	Target Neighborhood Hits	209	Shared Neighborhood Hits	17
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

HAPIP_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.057518 (rank : 81)
Query Neighborhood Hits	163	Target Neighborhood Hits	350	Shared Neighborhood Hits	24
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

MYCPP_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.063001 (rank : 80)
Query Neighborhood Hits	163	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z401, Q14655, Q86T77, Q8IVX2, Q8NB93	Gene names	MYCPBP, IRLB
Domain Architecture	No domain graphic available
Description	C-myc promoter-binding protein.

NGEF_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.050419 (rank : 87)
Query Neighborhood Hits	163	Target Neighborhood Hits	166	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

PKHG1_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.053656 (rank : 84)
Query Neighborhood Hits	163	Target Neighborhood Hits	174	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

PREX1_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.071239 (rank : 76)
Query Neighborhood Hits	163	Target Neighborhood Hits	177	Shared Neighborhood Hits	19
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

RA6I1_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.071594 (rank : 75)
Query Neighborhood Hits	163	Target Neighborhood Hits	63	Shared Neighborhood Hits	6
SwissProt Accessions	Q6IQ26, Q96GN3, Q9H6U7, Q9UFV0, Q9UPR1	Gene names	RAB6IP1, KIAA1091
Domain Architecture	No domain graphic available
Description	Rab6-interacting protein 1 (Rab6IP1).

RA6I1_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.072478 (rank : 74)
Query Neighborhood Hits	163	Target Neighborhood Hits	57	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PAL8, Q62146, Q8C829, Q8VDF6, Q9QYZ2	Gene names	Rab6ip1
Domain Architecture	No domain graphic available
Description	Rab6-interacting protein 1 (Rab6IP1).

RUFY3_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.108694 (rank : 66)
Query Neighborhood Hits	163	Target Neighborhood Hits	594	Shared Neighborhood Hits	16
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

RUFY3_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.109692 (rank : 65)
Query Neighborhood Hits	163	Target Neighborhood Hits	579	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

Hits sorted by NC score

MTMR3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	163	Target Neighborhood Hits	163	Shared Neighborhood Hits	163
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

MTMR3_MOUSE
NC score	0.881126 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	163	Target Neighborhood Hits	78	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K296	Gene names	Mtmr3
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48).

MTMR2_MOUSE
NC score	0.836262 (rank : 3)	θ value	1.14293e-95 (rank : 4)
Query Neighborhood Hits	163	Target Neighborhood Hits	29	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z2D1, Q8VHA7	Gene names	Mtmr2
Domain Architecture
Description	Myotubularin-related protein 2 (EC 3.1.3.-).

MTMR2_HUMAN
NC score	0.836185 (rank : 4)	θ value	2.30293e-96 (rank : 3)
Query Neighborhood Hits	163	Target Neighborhood Hits	29	Shared Neighborhood Hits	15
SwissProt Accessions	Q13614, Q9UPS9	Gene names	MTMR2, KIAA1073
Domain Architecture
Description	Myotubularin-related protein 2 (EC 3.1.3.-).

MTM1_HUMAN
NC score	0.835353 (rank : 5)	θ value	1.00126e-91 (rank : 5)
Query Neighborhood Hits	163	Target Neighborhood Hits	32	Shared Neighborhood Hits	16
SwissProt Accessions	Q13496, Q8NEL1	Gene names	MTM1, CG2
Domain Architecture
Description	Myotubularin (EC 3.1.3.48).

MTM1_MOUSE
NC score	0.834850 (rank : 6)	θ value	4.96919e-91 (rank : 6)
Query Neighborhood Hits	163	Target Neighborhood Hits	36	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z2C5	Gene names	Mtm1
Domain Architecture
Description	Myotubularin (EC 3.1.3.48).

MTMR1_HUMAN
NC score	0.831974 (rank : 7)	θ value	2.82168e-86 (rank : 7)
Query Neighborhood Hits	163	Target Neighborhood Hits	28	Shared Neighborhood Hits	15
SwissProt Accessions	Q13613, Q9UBX6, Q9UEM0, Q9UQD5	Gene names	MTMR1
Domain Architecture
Description	Myotubularin-related protein 1 (EC 3.1.3.-).

MTMR1_MOUSE
NC score	0.831718 (rank : 8)	θ value	3.11973e-85 (rank : 8)
Query Neighborhood Hits	163	Target Neighborhood Hits	23	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z2C4	Gene names	Mtmr1
Domain Architecture
Description	Myotubularin-related protein 1 (EC 3.1.3.-).

MTMR6_HUMAN
NC score	0.828540 (rank : 9)	θ value	3.34864e-71 (rank : 11)
Query Neighborhood Hits	163	Target Neighborhood Hits	39	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y217, Q86TB7, Q86YH4, Q96P80	Gene names	MTMR6
Domain Architecture
Description	Myotubularin-related protein 6 (EC 3.1.3.-).

MTMR9_MOUSE
NC score	0.824258 (rank : 10)	θ value	2.56992e-63 (rank : 13)
Query Neighborhood Hits	163	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z2D0, Q80XL4	Gene names	Mtmr9, Mtmr3
Domain Architecture
Description	Myotubularin-related protein 9.

MTMR7_HUMAN
NC score	0.824098 (rank : 11)	θ value	1.71583e-75 (rank : 9)
Query Neighborhood Hits	163	Target Neighborhood Hits	71	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y216, Q68DX4	Gene names	MTMR7
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

MTMR9_HUMAN
NC score	0.824059 (rank : 12)	θ value	2.56992e-63 (rank : 12)
Query Neighborhood Hits	163	Target Neighborhood Hits	16	Shared Neighborhood Hits	15
SwissProt Accessions	Q96QG7, Q52LU3, Q8WW11, Q96QG6, Q9NX50	Gene names	MTMR9, C8orf9, MTMR8
Domain Architecture
Description	Myotubularin-related protein 9.

MTMR7_MOUSE
NC score	0.822706 (rank : 13)	θ value	1.45253e-74 (rank : 10)
Query Neighborhood Hits	163	Target Neighborhood Hits	81	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z2C9, Q8C4J6	Gene names	Mtmr7
Domain Architecture
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

MTMR5_HUMAN
NC score	0.640529 (rank : 14)	θ value	1.05066e-40 (rank : 15)
Query Neighborhood Hits	163	Target Neighborhood Hits	141	Shared Neighborhood Hits	18
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

MTMRD_HUMAN
NC score	0.638989 (rank : 15)	θ value	1.12253e-42 (rank : 14)
Query Neighborhood Hits	163	Target Neighborhood Hits	135	Shared Neighborhood Hits	21
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

ZFY21_MOUSE
NC score	0.460339 (rank : 16)	θ value	3.18553e-13 (rank : 20)
Query Neighborhood Hits	163	Target Neighborhood Hits	72	Shared Neighborhood Hits	54
SwissProt Accessions	Q8VCM3, Q9D1E2	Gene names	Zfyve21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY21_HUMAN
NC score	0.458877 (rank : 17)	θ value	1.2105e-12 (rank : 22)
Query Neighborhood Hits	163	Target Neighborhood Hits	72	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BQ24, Q86T05, Q96LT1	Gene names	ZFYVE21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY28_HUMAN
NC score	0.447706 (rank : 18)	θ value	3.18553e-13 (rank : 21)
Query Neighborhood Hits	163	Target Neighborhood Hits	152	Shared Neighborhood Hits	55
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

PKHF2_MOUSE
NC score	0.402971 (rank : 19)	θ value	2.13673e-09 (rank : 40)
Query Neighborhood Hits	163	Target Neighborhood Hits	77	Shared Neighborhood Hits	48
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

PKHF2_HUMAN
NC score	0.402435 (rank : 20)	θ value	2.13673e-09 (rank : 39)
Query Neighborhood Hits	163	Target Neighborhood Hits	75	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

ZFYV9_HUMAN
NC score	0.398026 (rank : 21)	θ value	1.47974e-10 (rank : 30)
Query Neighborhood Hits	163	Target Neighborhood Hits	134	Shared Neighborhood Hits	55
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

ZFY16_MOUSE
NC score	0.395152 (rank : 22)	θ value	1.33837e-11 (rank : 23)
Query Neighborhood Hits	163	Target Neighborhood Hits	108	Shared Neighborhood Hits	55
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

PKHF1_HUMAN
NC score	0.394109 (rank : 23)	θ value	3.41135e-07 (rank : 44)
Query Neighborhood Hits	163	Target Neighborhood Hits	76	Shared Neighborhood Hits	50
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

PKHF1_MOUSE
NC score	0.389431 (rank : 24)	θ value	7.59969e-07 (rank : 46)
Query Neighborhood Hits	163	Target Neighborhood Hits	80	Shared Neighborhood Hits	50
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

ZFY16_HUMAN
NC score	0.389122 (rank : 25)	θ value	3.89403e-11 (rank : 27)
Query Neighborhood Hits	163	Target Neighborhood Hits	125	Shared Neighborhood Hits	54
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

ZFYV1_HUMAN
NC score	0.378887 (rank : 26)	θ value	1.47974e-10 (rank : 29)
Query Neighborhood Hits	163	Target Neighborhood Hits	166	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

ZFYV1_MOUSE
NC score	0.375909 (rank : 27)	θ value	7.34386e-10 (rank : 35)
Query Neighborhood Hits	163	Target Neighborhood Hits	153	Shared Neighborhood Hits	55
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

FYV1_MOUSE
NC score	0.332048 (rank : 28)	θ value	2.98157e-11 (rank : 26)
Query Neighborhood Hits	163	Target Neighborhood Hits	191	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

FYV1_HUMAN
NC score	0.331786 (rank : 29)	θ value	2.98157e-11 (rank : 25)
Query Neighborhood Hits	163	Target Neighborhood Hits	217	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

HGS_HUMAN
NC score	0.326597 (rank : 30)	θ value	2.36244e-08 (rank : 42)
Query Neighborhood Hits	163	Target Neighborhood Hits	517	Shared Neighborhood Hits	64
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HGS_MOUSE
NC score	0.325274 (rank : 31)	θ value	1.80886e-08 (rank : 41)
Query Neighborhood Hits	163	Target Neighborhood Hits	589	Shared Neighborhood Hits	65
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

FGD6_HUMAN
NC score	0.315922 (rank : 32)	θ value	1.9326e-10 (rank : 31)
Query Neighborhood Hits	163	Target Neighborhood Hits	237	Shared Neighborhood Hits	52
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

ZFY19_HUMAN
NC score	0.310530 (rank : 33)	θ value	1.43324e-05 (rank : 52)
Query Neighborhood Hits	163	Target Neighborhood Hits	206	Shared Neighborhood Hits	54
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

ZFY19_MOUSE
NC score	0.309269 (rank : 34)	θ value	5.44631e-05 (rank : 56)
Query Neighborhood Hits	163	Target Neighborhood Hits	143	Shared Neighborhood Hits	52
SwissProt Accessions	Q9DAZ9, Q8VCV7	Gene names	Zfyve19
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19.

FGD6_MOUSE
NC score	0.307662 (rank : 35)	θ value	9.59137e-10 (rank : 37)
Query Neighborhood Hits	163	Target Neighborhood Hits	282	Shared Neighborhood Hits	55
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

FGD5_MOUSE
NC score	0.293845 (rank : 36)	θ value	0.00035302 (rank : 59)
Query Neighborhood Hits	163	Target Neighborhood Hits	170	Shared Neighborhood Hits	56
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

ZFY27_HUMAN
NC score	0.287738 (rank : 37)	θ value	1.29631e-06 (rank : 47)
Query Neighborhood Hits	163	Target Neighborhood Hits	64	Shared Neighborhood Hits	45
SwissProt Accessions	Q5T4F4, Q5T4F1, Q5T4F2, Q5T4F3, Q8N1K0, Q8N6D6, Q8NCA0, Q8NDE4, Q96M08	Gene names	ZFYVE27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

FGD5_HUMAN
NC score	0.287148 (rank : 38)	θ value	0.000270298 (rank : 58)
Query Neighborhood Hits	163	Target Neighborhood Hits	235	Shared Neighborhood Hits	56
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

ZFY27_MOUSE
NC score	0.285604 (rank : 39)	θ value	2.88788e-06 (rank : 49)
Query Neighborhood Hits	163	Target Neighborhood Hits	53	Shared Neighborhood Hits	45
SwissProt Accessions	Q3TXX3, Q8CFP8	Gene names	Zfyve27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

RBNS5_HUMAN
NC score	0.282042 (rank : 40)	θ value	0.000786445 (rank : 61)
Query Neighborhood Hits	163	Target Neighborhood Hits	242	Shared Neighborhood Hits	55
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

RBNS5_MOUSE
NC score	0.277688 (rank : 41)	θ value	0.00134147 (rank : 63)
Query Neighborhood Hits	163	Target Neighborhood Hits	266	Shared Neighborhood Hits	51
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

RUFY1_MOUSE
NC score	0.274404 (rank : 42)	θ value	8.95645e-16 (rank : 17)
Query Neighborhood Hits	163	Target Neighborhood Hits	765	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

FGD2_MOUSE
NC score	0.270512 (rank : 43)	θ value	4.45536e-07 (rank : 45)
Query Neighborhood Hits	163	Target Neighborhood Hits	163	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

FGD2_HUMAN
NC score	0.269065 (rank : 44)	θ value	4.92598e-06 (rank : 50)
Query Neighborhood Hits	163	Target Neighborhood Hits	151	Shared Neighborhood Hits	52
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

RUFY1_HUMAN
NC score	0.265082 (rank : 45)	θ value	6.85773e-16 (rank : 16)
Query Neighborhood Hits	163	Target Neighborhood Hits	848	Shared Neighborhood Hits	63
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

RUFY2_MOUSE
NC score	0.264718 (rank : 46)	θ value	1.68911e-14 (rank : 19)
Query Neighborhood Hits	163	Target Neighborhood Hits	820	Shared Neighborhood Hits	63
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

FGD4_HUMAN
NC score	0.254779 (rank : 47)	θ value	2.88788e-06 (rank : 48)
Query Neighborhood Hits	163	Target Neighborhood Hits	219	Shared Neighborhood Hits	49
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD4_MOUSE
NC score	0.253284 (rank : 48)	θ value	1.43324e-05 (rank : 51)
Query Neighborhood Hits	163	Target Neighborhood Hits	227	Shared Neighborhood Hits	50
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

WDFY3_MOUSE
NC score	0.249676 (rank : 49)	θ value	2.52405e-10 (rank : 33)
Query Neighborhood Hits	163	Target Neighborhood Hits	332	Shared Neighborhood Hits	57
SwissProt Accessions	Q6VNB8, Q8C8H7	Gene names	Wdfy3
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1).

WDFY3_HUMAN
NC score	0.248968 (rank : 50)	θ value	2.52405e-10 (rank : 32)
Query Neighborhood Hits	163	Target Neighborhood Hits	348	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

FGD1_HUMAN
NC score	0.242349 (rank : 51)	θ value	0.000786445 (rank : 60)
Query Neighborhood Hits	163	Target Neighborhood Hits	367	Shared Neighborhood Hits	58
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_MOUSE
NC score	0.241674 (rank : 52)	θ value	0.00102713 (rank : 62)
Query Neighborhood Hits	163	Target Neighborhood Hits	387	Shared Neighborhood Hits	57
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

WDFY1_HUMAN
NC score	0.238336 (rank : 53)	θ value	2.44474e-05 (rank : 53)
Query Neighborhood Hits	163	Target Neighborhood Hits	305	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IWB7, Q9H9D5, Q9P2B3	Gene names	WDFY1, KIAA1435, WDF1, ZFYVE17
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 1 (WD40- and FYVE domain- containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain-containing protein 17).

WDFY2_MOUSE
NC score	0.233942 (rank : 54)	θ value	4.1701e-05 (rank : 55)
Query Neighborhood Hits	163	Target Neighborhood Hits	337	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BUB4	Gene names	Wdfy2
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2).

FGD3_HUMAN
NC score	0.233540 (rank : 55)	θ value	0.000158464 (rank : 57)
Query Neighborhood Hits	163	Target Neighborhood Hits	249	Shared Neighborhood Hits	55
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

WDFY2_HUMAN
NC score	0.231928 (rank : 56)	θ value	4.1701e-05 (rank : 54)
Query Neighborhood Hits	163	Target Neighborhood Hits	332	Shared Neighborhood Hits	49
SwissProt Accessions	Q96P53, Q96CS1	Gene names	WDFY2, WDF2, ZFYVE22
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2) (Zinc finger FYVE domain-containing protein 22).

RUFY2_HUMAN
NC score	0.209850 (rank : 57)	θ value	1.68911e-14 (rank : 18)
Query Neighborhood Hits	163	Target Neighborhood Hits	1208	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

FGD3_MOUSE
NC score	0.205128 (rank : 58)	θ value	0.0736092 (rank : 65)
Query Neighborhood Hits	163	Target Neighborhood Hits	257	Shared Neighborhood Hits	53
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

FYCO1_HUMAN
NC score	0.173450 (rank : 59)	θ value	4.30538e-10 (rank : 34)
Query Neighborhood Hits	163	Target Neighborhood Hits	1149	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

ANFY1_MOUSE
NC score	0.171052 (rank : 60)	θ value	1.25267e-09 (rank : 38)
Query Neighborhood Hits	163	Target Neighborhood Hits	480	Shared Neighborhood Hits	56
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANFY1_HUMAN
NC score	0.170214 (rank : 61)	θ value	9.59137e-10 (rank : 36)
Query Neighborhood Hits	163	Target Neighborhood Hits	480	Shared Neighborhood Hits	54
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

FYCO1_MOUSE
NC score	0.163517 (rank : 62)	θ value	5.26297e-08 (rank : 43)
Query Neighborhood Hits	163	Target Neighborhood Hits	1059	Shared Neighborhood Hits	63
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

EEA1_MOUSE
NC score	0.151436 (rank : 63)	θ value	6.64225e-11 (rank : 28)
Query Neighborhood Hits	163	Target Neighborhood Hits	1637	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

EEA1_HUMAN
NC score	0.140036 (rank : 64)	θ value	2.28291e-11 (rank : 24)
Query Neighborhood Hits	163	Target Neighborhood Hits	1796	Shared Neighborhood Hits	80
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

RUFY3_MOUSE
NC score	0.109692 (rank : 65)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	163	Target Neighborhood Hits	579	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

RUFY3_HUMAN
NC score	0.108694 (rank : 66)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	163	Target Neighborhood Hits	594	Shared Neighborhood Hits	16
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

RNF34_MOUSE
NC score	0.094047 (rank : 67)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	163	Target Neighborhood Hits	160	Shared Neighborhood Hits	36
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RNF34_HUMAN
NC score	0.091050 (rank : 68)	θ value	1.81305 (rank : 93)
Query Neighborhood Hits	163	Target Neighborhood Hits	153	Shared Neighborhood Hits	34
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RFFL_MOUSE
NC score	0.085403 (rank : 69)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	163	Target Neighborhood Hits	145	Shared Neighborhood Hits	37
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RFFL_HUMAN
NC score	0.081132 (rank : 70)	θ value	2.36792 (rank : 100)
Query Neighborhood Hits	163	Target Neighborhood Hits	175	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

FARP1_HUMAN
NC score	0.075897 (rank : 71)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	163	Target Neighborhood Hits	241	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FARP2_HUMAN
NC score	0.074646 (rank : 72)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	163	Target Neighborhood Hits	240	Shared Neighborhood Hits	19
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_MOUSE
NC score	0.073036 (rank : 73)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	163	Target Neighborhood Hits	209	Shared Neighborhood Hits	17
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

RA6I1_MOUSE
NC score	0.072478 (rank : 74)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	163	Target Neighborhood Hits	57	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PAL8, Q62146, Q8C829, Q8VDF6, Q9QYZ2	Gene names	Rab6ip1
Domain Architecture	No domain graphic available
Description	Rab6-interacting protein 1 (Rab6IP1).

RA6I1_HUMAN
NC score	0.071594 (rank : 75)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	163	Target Neighborhood Hits	63	Shared Neighborhood Hits	6
SwissProt Accessions	Q6IQ26, Q96GN3, Q9H6U7, Q9UFV0, Q9UPR1	Gene names	RAB6IP1, KIAA1091
Domain Architecture	No domain graphic available
Description	Rab6-interacting protein 1 (Rab6IP1).

PREX1_HUMAN
NC score	0.071239 (rank : 76)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	163	Target Neighborhood Hits	177	Shared Neighborhood Hits	19
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

CJ064_HUMAN
NC score	0.066050 (rank : 77)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	163	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZS81, Q8N4A3	Gene names	C10orf64
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf64.

ECT2_MOUSE
NC score	0.064539 (rank : 78)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	163	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ECT2_HUMAN
NC score	0.063044 (rank : 79)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	163	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

MYCPP_HUMAN
NC score	0.063001 (rank : 80)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	163	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z401, Q14655, Q86T77, Q8IVX2, Q8NB93	Gene names	MYCPBP, IRLB
Domain Architecture	No domain graphic available
Description	C-myc promoter-binding protein.

HAPIP_HUMAN
NC score	0.057518 (rank : 81)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	163	Target Neighborhood Hits	350	Shared Neighborhood Hits	24
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

ARHG5_HUMAN
NC score	0.056316 (rank : 82)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	163	Target Neighborhood Hits	172	Shared Neighborhood Hits	14
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

ARHGA_MOUSE
NC score	0.053795 (rank : 83)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	163	Target Neighborhood Hits	125	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

PKHG1_HUMAN
NC score	0.053656 (rank : 84)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	163	Target Neighborhood Hits	174	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

ARHGA_HUMAN
NC score	0.052955 (rank : 85)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	163	Target Neighborhood Hits	187	Shared Neighborhood Hits	15
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

DEN4C_HUMAN
NC score	0.051309 (rank : 86)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	163	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VZ89, Q6AI48, Q6ZUB3, Q8NCY7, Q9H6N4, Q9NUT1, Q9NWA5	Gene names	DENND4C, C9orf55
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 4C.

NGEF_HUMAN
NC score	0.050419 (rank : 87)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	163	Target Neighborhood Hits	166	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

CM007_HUMAN
NC score	0.048551 (rank : 88)	θ value	0.813845 (rank : 74)
Query Neighborhood Hits	163	Target Neighborhood Hits	422	Shared Neighborhood Hits	16
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

CM007_MOUSE
NC score	0.047456 (rank : 89)	θ value	0.21417 (rank : 68)
Query Neighborhood Hits	163	Target Neighborhood Hits	416	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

MCPH1_HUMAN
NC score	0.034800 (rank : 90)	θ value	0.163984 (rank : 67)
Query Neighborhood Hits	163	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEM0, Q66GU1, Q9H9C7	Gene names	MCPH1
Domain Architecture
Description	Microcephalin.

SYNE1_HUMAN
NC score	0.031681 (rank : 91)	θ value	0.279714 (rank : 69)
Query Neighborhood Hits	163	Target Neighborhood Hits	1484	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

SPAG5_HUMAN
NC score	0.031315 (rank : 92)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	163	Target Neighborhood Hits	625	Shared Neighborhood Hits	20
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

TRIPB_HUMAN
NC score	0.030796 (rank : 93)	θ value	4.03905 (rank : 122)
Query Neighborhood Hits	163	Target Neighborhood Hits	1587	Shared Neighborhood Hits	37
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CJ118_MOUSE
NC score	0.028761 (rank : 94)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	163	Target Neighborhood Hits	1132	Shared Neighborhood Hits	28
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

SMR1_MOUSE
NC score	0.028085 (rank : 95)	θ value	1.38821 (rank : 85)
Query Neighborhood Hits	163	Target Neighborhood Hits	103	Shared Neighborhood Hits	5
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

CROCC_HUMAN
NC score	0.027802 (rank : 96)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	163	Target Neighborhood Hits	1409	Shared Neighborhood Hits	32
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

IP3KC_HUMAN
NC score	0.026703 (rank : 97)	θ value	0.0736092 (rank : 66)
Query Neighborhood Hits	163	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q96DU7, Q9UE25, Q9Y475	Gene names	ITPKC, IP3KC
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase C) (InsP 3-kinase C) (IP3K-C).

PALM_HUMAN
NC score	0.024268 (rank : 98)	θ value	1.81305 (rank : 89)
Query Neighborhood Hits	163	Target Neighborhood Hits	136	Shared Neighborhood Hits	7
SwissProt Accessions	O75781, O43359, O95673, Q92559, Q9UPJ4, Q9UQS2, Q9UQS3	Gene names	PALM, KIAA0270
Domain Architecture
Description	Paralemmin.

MCPH1_MOUSE
NC score	0.024091 (rank : 99)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	163	Target Neighborhood Hits	116	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

DZIP1_MOUSE
NC score	0.023709 (rank : 100)	θ value	2.36792 (rank : 97)
Query Neighborhood Hits	163	Target Neighborhood Hits	530	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BMD2, Q6ZQ10, Q9CRK5	Gene names	Dzip1, Kiaa0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog).

CCD45_HUMAN
NC score	0.022761 (rank : 101)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	163	Target Neighborhood Hits	525	Shared Neighborhood Hits	16
SwissProt Accessions	Q96GE4, Q96M81	Gene names	CCDC45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

TTC14_HUMAN
NC score	0.022255 (rank : 102)	θ value	2.36792 (rank : 101)
Query Neighborhood Hits	163	Target Neighborhood Hits	274	Shared Neighborhood Hits	9
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

TRDN_HUMAN
NC score	0.021930 (rank : 103)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	163	Target Neighborhood Hits	542	Shared Neighborhood Hits	18
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TM108_MOUSE
NC score	0.021025 (rank : 104)	θ value	0.813845 (rank : 76)
Query Neighborhood Hits	163	Target Neighborhood Hits	336	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

A16L1_MOUSE
NC score	0.020926 (rank : 105)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	163	Target Neighborhood Hits	776	Shared Neighborhood Hits	22
SwissProt Accessions	Q8C0J2, Q6KAT7, Q80U97, Q80U98, Q80U99, Q80Y53, Q9DB63	Gene names	Atg16l1, Apg16l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

CENPJ_HUMAN
NC score	0.020752 (rank : 106)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	163	Target Neighborhood Hits	721	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

CN044_HUMAN
NC score	0.020352 (rank : 107)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	163	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	Q96MY7	Gene names	C14orf44
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf44.

MYRIP_HUMAN
NC score	0.019968 (rank : 108)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	163	Target Neighborhood Hits	269	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

HIRP3_HUMAN
NC score	0.018398 (rank : 109)	θ value	2.36792 (rank : 98)
Query Neighborhood Hits	163	Target Neighborhood Hits	323	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

TSKS_MOUSE
NC score	0.017343 (rank : 110)	θ value	1.81305 (rank : 94)
Query Neighborhood Hits	163	Target Neighborhood Hits	188	Shared Neighborhood Hits	8
SwissProt Accessions	O54887	Gene names	Stk22s1, Tsks
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

AKA12_HUMAN
NC score	0.016927 (rank : 111)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	163	Target Neighborhood Hits	825	Shared Neighborhood Hits	19
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

ABI3_MOUSE
NC score	0.016717 (rank : 112)	θ value	1.06291 (rank : 77)
Query Neighborhood Hits	163	Target Neighborhood Hits	227	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

RENT1_HUMAN
NC score	0.016170 (rank : 113)	θ value	1.81305 (rank : 91)
Query Neighborhood Hits	163	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

RENT1_MOUSE
NC score	0.016142 (rank : 114)	θ value	1.81305 (rank : 92)
Query Neighborhood Hits	163	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

MRIP_MOUSE
NC score	0.016026 (rank : 115)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	163	Target Neighborhood Hits	569	Shared Neighborhood Hits	16
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

ZN313_HUMAN
NC score	0.015845 (rank : 116)	θ value	1.06291 (rank : 79)
Query Neighborhood Hits	163	Target Neighborhood Hits	264	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

ZN313_MOUSE
NC score	0.015439 (rank : 117)	θ value	1.06291 (rank : 80)
Query Neighborhood Hits	163	Target Neighborhood Hits	273	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

ABI3_HUMAN
NC score	0.014551 (rank : 118)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	163	Target Neighborhood Hits	227	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

TNR6A_HUMAN
NC score	0.014040 (rank : 119)	θ value	3.0926 (rank : 111)
Query Neighborhood Hits	163	Target Neighborhood Hits	343	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

DAAM2_MOUSE
NC score	0.013920 (rank : 120)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	163	Target Neighborhood Hits	371	Shared Neighborhood Hits	11
SwissProt Accessions	Q80U19, Q810J5	Gene names	Daam2, Kiaa0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

CN044_MOUSE
NC score	0.013867 (rank : 121)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	163	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CB59, Q8BQX8, Q8BSL9, Q8CBZ3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf44 homolog.

HEM1_MOUSE
NC score	0.013613 (rank : 122)	θ value	0.813845 (rank : 75)
Query Neighborhood Hits	163	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VC19, Q64453	Gene names	Alas1
Domain Architecture	No domain graphic available
Description	5-aminolevulinate synthase, nonspecific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-H).

RXINP_HUMAN
NC score	0.013607 (rank : 123)	θ value	3.0926 (rank : 109)
Query Neighborhood Hits	163	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q96RL1, Q5XKQ1, Q7Z3W7, Q8N5B9, Q9BZR1, Q9BZR5, Q9UHX7	Gene names	RXRIP110, RAP80
Domain Architecture	No domain graphic available
Description	Retinoid X receptor-interacting protein 110 (Receptor-associated protein 80) (Nuclear zinc finger protein RAP80).

CHFR_MOUSE
NC score	0.013250 (rank : 124)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	163	Target Neighborhood Hits	264	Shared Neighborhood Hits	10
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

RTN2_HUMAN
NC score	0.012198 (rank : 125)	θ value	3.0926 (rank : 108)
Query Neighborhood Hits	163	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	O75298, O60509, Q7RTM6, Q7RTN1, Q7RTN2	Gene names	RTN2, NSPL1
Domain Architecture
Description	Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (NSPLI).

NASP_HUMAN
NC score	0.012159 (rank : 126)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	163	Target Neighborhood Hits	709	Shared Neighborhood Hits	19
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

FHOD1_HUMAN
NC score	0.011896 (rank : 127)	θ value	3.0926 (rank : 104)
Query Neighborhood Hits	163	Target Neighborhood Hits	184	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

STRC_MOUSE
NC score	0.011797 (rank : 128)	θ value	3.0926 (rank : 110)
Query Neighborhood Hits	163	Target Neighborhood Hits	89	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VIM6	Gene names	Strc
Domain Architecture	No domain graphic available
Description	Stereocilin precursor.

CBP_HUMAN
NC score	0.011771 (rank : 129)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	163	Target Neighborhood Hits	941	Shared Neighborhood Hits	24
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

PTN21_HUMAN
NC score	0.011479 (rank : 130)	θ value	0.0431538 (rank : 64)
Query Neighborhood Hits	163	Target Neighborhood Hits	143	Shared Neighborhood Hits	5
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

DDX21_MOUSE
NC score	0.010290 (rank : 131)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	163	Target Neighborhood Hits	350	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

PTPRV_MOUSE
NC score	0.009862 (rank : 132)	θ value	4.03905 (rank : 121)
Query Neighborhood Hits	163	Target Neighborhood Hits	179	Shared Neighborhood Hits	9
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

TSYL1_HUMAN
NC score	0.009114 (rank : 133)	θ value	3.0926 (rank : 112)
Query Neighborhood Hits	163	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H0U9, O75885	Gene names	TSPYL1, TSPYL
Domain Architecture
Description	Testis-specific Y-encoded-like protein 1 (TSPY-like 1).

FBX42_HUMAN
NC score	0.009017 (rank : 134)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	163	Target Neighborhood Hits	121	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P3S6, Q5TEU8, Q86XI0, Q8N3N4, Q8N5F8, Q9BRM0, Q9P2L4	Gene names	FBXO42, FBX42, KIAA1332
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

RTN4_MOUSE
NC score	0.008987 (rank : 135)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	163	Target Neighborhood Hits	341	Shared Neighborhood Hits	8
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

BCL9_HUMAN
NC score	0.008947 (rank : 136)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	163	Target Neighborhood Hits	1008	Shared Neighborhood Hits	22
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

MINT_MOUSE
NC score	0.008906 (rank : 137)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	163	Target Neighborhood Hits	1514	Shared Neighborhood Hits	34
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PA24E_MOUSE
NC score	0.008663 (rank : 138)	θ value	1.38821 (rank : 84)
Query Neighborhood Hits	163	Target Neighborhood Hits	95	Shared Neighborhood Hits	2
SwissProt Accessions	Q50L42, Q8BX44	Gene names	Pla2g4e
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

LAMA5_HUMAN
NC score	0.008435 (rank : 139)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	163	Target Neighborhood Hits	976	Shared Neighborhood Hits	26
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

FGL2_MOUSE
NC score	0.008297 (rank : 140)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	163	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	P12804	Gene names	Fgl2, Fiblp
Domain Architecture
Description	Fibroleukin precursor (Fibrinogen-like protein 2) (Prothrombinase) (Cytotoxic T-lymphocyte-specific protein).

TBC14_HUMAN
NC score	0.008291 (rank : 141)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	163	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P2M4, Q8IW15	Gene names	TBC1D14, KIAA1322
Domain Architecture
Description	TBC1 domain family member 14.

TBC14_MOUSE
NC score	0.008066 (rank : 142)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	163	Target Neighborhood Hits	135	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CGA2, Q8CHA5	Gene names	Tbc1d14, D5Ertd110e, Kiaa1322
Domain Architecture
Description	TBC1 domain family member 14.

NKTR_HUMAN
NC score	0.008059 (rank : 143)	θ value	1.38821 (rank : 83)
Query Neighborhood Hits	163	Target Neighborhood Hits	658	Shared Neighborhood Hits	17
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

WWC1_MOUSE
NC score	0.008046 (rank : 144)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	163	Target Neighborhood Hits	290	Shared Neighborhood Hits	10
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

ANKS1_HUMAN
NC score	0.007964 (rank : 145)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	163	Target Neighborhood Hits	438	Shared Neighborhood Hits	6
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

CO3A1_HUMAN
NC score	0.007728 (rank : 146)	θ value	0.365318 (rank : 70)
Query Neighborhood Hits	163	Target Neighborhood Hits	452	Shared Neighborhood Hits	12
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

MUC5B_HUMAN
NC score	0.007520 (rank : 147)	θ value	4.03905 (rank : 120)
Query Neighborhood Hits	163	Target Neighborhood Hits	1020	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

TRI44_MOUSE
NC score	0.007460 (rank : 148)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	163	Target Neighborhood Hits	327	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

SENP6_HUMAN
NC score	0.007162 (rank : 149)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	163	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZR1, O94891, Q8TBY4, Q9UJV5	Gene names	SENP6, KIAA0797, SSP1, SUSP1
Domain Architecture
Description	Sentrin-specific protease 6 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP6) (SUMO-1-specific protease 1).

PTPRO_HUMAN
NC score	0.007117 (rank : 150)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	163	Target Neighborhood Hits	139	Shared Neighborhood Hits	6
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

MUC2_HUMAN
NC score	0.007006 (rank : 151)	θ value	2.36792 (rank : 99)
Query Neighborhood Hits	163	Target Neighborhood Hits	906	Shared Neighborhood Hits	12
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MEF2C_HUMAN
NC score	0.006875 (rank : 152)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	163	Target Neighborhood Hits	90	Shared Neighborhood Hits	2
SwissProt Accessions	Q06413	Gene names	MEF2C
Domain Architecture
Description	Myocyte-specific enhancer factor 2C.

NIBA_HUMAN
NC score	0.006532 (rank : 153)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	163	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZQ8, Q5TEM8, Q8TEI5, Q9H593, Q9H9Y8, Q9HCB9	Gene names	C1orf24
Domain Architecture	No domain graphic available
Description	Niban protein.

ASPM_MOUSE
NC score	0.006011 (rank : 154)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	163	Target Neighborhood Hits	150	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CJ27, O88482, Q8BJI8, Q8BKT4	Gene names	Aspm, Calmbp1, Sha1
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein homolog (Calmodulin-binding protein 1) (Spindle and hydroxyurea checkpoint abnormal protein) (Calmodulin-binding protein Sha1).

NOS3_MOUSE
NC score	0.005147 (rank : 155)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	163	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	P70313, O55056	Gene names	Nos3, Ecnos
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

DUS3_HUMAN
NC score	0.004886 (rank : 156)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	163	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	P51452	Gene names	DUSP3, VHR
Domain Architecture
Description	Dual specificity protein phosphatase 3 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase VHR).

FINC_HUMAN
NC score	0.004863 (rank : 157)	θ value	3.0926 (rank : 105)
Query Neighborhood Hits	163	Target Neighborhood Hits	302	Shared Neighborhood Hits	7
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

IGHA1_HUMAN
NC score	0.004833 (rank : 158)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	163	Target Neighborhood Hits	194	Shared Neighborhood Hits	4
SwissProt Accessions	P01876	Gene names	IGHA1
Domain Architecture
Description	Ig alpha-1 chain C region.

NSBP1_MOUSE
NC score	0.004829 (rank : 159)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	163	Target Neighborhood Hits	681	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

SNX1_MOUSE
NC score	0.004580 (rank : 160)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	163	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WV80, Q9EQZ9	Gene names	Snx1
Domain Architecture
Description	Sorting nexin-1.

PKNX1_HUMAN
NC score	0.004466 (rank : 161)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	163	Target Neighborhood Hits	101	Shared Neighborhood Hits	3
SwissProt Accessions	P55347, O00528, Q8IWT7	Gene names	PKNOX1, PREP1
Domain Architecture
Description	Homeobox protein PKNOX1 (PBX/knotted homeobox 1) (Homeobox protein PREP-1).

KCNH2_HUMAN
NC score	0.004243 (rank : 162)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	163	Target Neighborhood Hits	158	Shared Neighborhood Hits	2
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

TEX14_HUMAN
NC score	0.004068 (rank : 163)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	163	Target Neighborhood Hits	1103	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

MLL4_HUMAN
NC score	0.002933 (rank : 164)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	163	Target Neighborhood Hits	722	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

LMO6_MOUSE
NC score	0.002862 (rank : 165)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	163	Target Neighborhood Hits	277	Shared Neighborhood Hits	5
SwissProt Accessions	Q80VL3, Q8CAY9	Gene names	Lmo6
Domain Architecture	No domain graphic available
Description	LIM domain only protein 6 (Triple LIM domain protein 6).

COIA1_HUMAN
NC score	0.002788 (rank : 166)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	163	Target Neighborhood Hits	447	Shared Neighborhood Hits	12
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

SFPQ_HUMAN
NC score	0.002769 (rank : 167)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	163	Target Neighborhood Hits	986	Shared Neighborhood Hits	19
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

RAF1_MOUSE
NC score	0.001721 (rank : 168)	θ value	0.62314 (rank : 73)
Query Neighborhood Hits	163	Target Neighborhood Hits	886	Shared Neighborhood Hits	11
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

INSM1_HUMAN
NC score	0.000003 (rank : 169)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	163	Target Neighborhood Hits	683	Shared Neighborhood Hits	11
SwissProt Accessions	Q01101	Gene names	INSM1, IA1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

ZN653_HUMAN
NC score	-0.000496 (rank : 170)	θ value	0.47712 (rank : 71)
Query Neighborhood Hits	163	Target Neighborhood Hits	719	Shared Neighborhood Hits	7
SwissProt Accessions	Q96CK0, Q96AS7	Gene names	ZNF653, ZIP67
Domain Architecture	No domain graphic available
Description	Zinc finger protein 653 (67 kDa zinc finger protein) (Zinc finger protein Zip67).

PGBM_HUMAN
NC score	-0.000608 (rank : 171)	θ value	1.81305 (rank : 90)
Query Neighborhood Hits	163	Target Neighborhood Hits	1113	Shared Neighborhood Hits	13
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PIM1_HUMAN
NC score	-0.000812 (rank : 172)	θ value	0.62314 (rank : 72)
Query Neighborhood Hits	163	Target Neighborhood Hits	797	Shared Neighborhood Hits	7
SwissProt Accessions	P11309, Q38RT9, Q96RG3	Gene names	PIM1
Domain Architecture
Description	Proto-oncogene serine/threonine-protein kinase Pim-1 (EC 2.7.11.1).

FLRT2_HUMAN
NC score	-0.000813 (rank : 173)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	163	Target Neighborhood Hits	295	Shared Neighborhood Hits	2
SwissProt Accessions	O43155	Gene names	FLRT2, KIAA0405
Domain Architecture
Description	Leucine-rich repeat transmembrane protein FLRT2 precursor (Fibronectin-like domain-containing leucine-rich transmembrane protein 2).

BC11B_MOUSE
NC score	-0.001811 (rank : 174)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	163	Target Neighborhood Hits	767	Shared Neighborhood Hits	10
SwissProt Accessions	Q99PV8, Q8C2I1, Q99PV6, Q99PV7, Q9JLF8	Gene names	Bcl11b, Ctip2, Rit1
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11B (B-cell CLL/lymphoma 11B) (Radiation- induced tumor suppressor gene 1 protein) (mRit1) (COUP-TF-interacting protein 2).

ZN653_MOUSE
NC score	-0.001984 (rank : 175)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	163	Target Neighborhood Hits	744	Shared Neighborhood Hits	7
SwissProt Accessions	Q6YND2, Q8BHT8, Q8CI02	Gene names	Znf653, Zfp653, Zip67
Domain Architecture	No domain graphic available
Description	Zinc finger protein 653 (67 kDa zinc finger protein) (Zinc finger protein Zip67).

WNK3_HUMAN
NC score	-0.002241 (rank : 176)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	163	Target Neighborhood Hits	948	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

ZN646_HUMAN
NC score	-0.002355 (rank : 177)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	163	Target Neighborhood Hits	813	Shared Neighborhood Hits	13
SwissProt Accessions	O15015	Gene names	ZNF646, KIAA0296
Domain Architecture	No domain graphic available
Description	Zinc finger protein 646.

RAF1_HUMAN
NC score	-0.002920 (rank : 178)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	163	Target Neighborhood Hits	886	Shared Neighborhood Hits	10
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

NUAK2_HUMAN
NC score	-0.003022 (rank : 179)	θ value	1.06291 (rank : 78)
Query Neighborhood Hits	163	Target Neighborhood Hits	874	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H093	Gene names	NUAK2
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (SNF1/AMP kinase-related kinase) (SNARK).

KPCE_MOUSE
NC score	-0.004237 (rank : 180)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	163	Target Neighborhood Hits	906	Shared Neighborhood Hits	9
SwissProt Accessions	P16054	Gene names	Prkce, Pkce, Pkcea
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

ZN670_HUMAN
NC score	-0.004552 (rank : 181)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	163	Target Neighborhood Hits	736	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BS34	Gene names	ZNF670
Domain Architecture	No domain graphic available
Description	Zinc finger protein 670.

ZN490_HUMAN
NC score	-0.004758 (rank : 182)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	163	Target Neighborhood Hits	754	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ULM2	Gene names	ZNF490, KIAA1198
Domain Architecture
Description	Zinc finger protein 490.