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Network neighborhood for query Sequence : RA6I1_HUMAN

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RA6I1_HUMAN
SwissProt Accessions	Q6IQ26, Q96GN3, Q9H6U7, Q9UFV0, Q9UPR1	Gene names	RAB6IP1, KIAA1091
Domain Architecture	No domain graphic available
Description	Rab6-interacting protein 1 (Rab6IP1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RA6I1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	63	Target Neighborhood Hits	63	Shared Neighborhood Hits	63
SwissProt Accessions	Q6IQ26, Q96GN3, Q9H6U7, Q9UFV0, Q9UPR1	Gene names	RAB6IP1, KIAA1091
Domain Architecture	No domain graphic available
Description	Rab6-interacting protein 1 (Rab6IP1).

RA6I1_MOUSE
θ value	0 (rank : 2)	NC score	0.998895 (rank : 2)
Query Neighborhood Hits	63	Target Neighborhood Hits	57	Shared Neighborhood Hits	53
SwissProt Accessions	Q6PAL8, Q62146, Q8C829, Q8VDF6, Q9QYZ2	Gene names	Rab6ip1
Domain Architecture	No domain graphic available
Description	Rab6-interacting protein 1 (Rab6IP1).

DEN4C_HUMAN
θ value	3.17079e-29 (rank : 3)	NC score	0.683970 (rank : 4)
Query Neighborhood Hits	63	Target Neighborhood Hits	63	Shared Neighborhood Hits	17
SwissProt Accessions	Q5VZ89, Q6AI48, Q6ZUB3, Q8NCY7, Q9H6N4, Q9NUT1, Q9NWA5	Gene names	DENND4C, C9orf55
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 4C.

MYCPP_HUMAN
θ value	3.17079e-29 (rank : 4)	NC score	0.686494 (rank : 3)
Query Neighborhood Hits	63	Target Neighborhood Hits	51	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z401, Q14655, Q86T77, Q8IVX2, Q8NB93	Gene names	MYCPBP, IRLB
Domain Architecture	No domain graphic available
Description	C-myc promoter-binding protein.

MTMR5_HUMAN
θ value	1.6852e-22 (rank : 5)	NC score	0.482008 (rank : 15)
Query Neighborhood Hits	63	Target Neighborhood Hits	141	Shared Neighborhood Hits	16
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

MTMRD_HUMAN
θ value	1.86321e-21 (rank : 6)	NC score	0.479199 (rank : 16)
Query Neighborhood Hits	63	Target Neighborhood Hits	135	Shared Neighborhood Hits	16
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

DEN1A_MOUSE
θ value	1.63225e-17 (rank : 7)	NC score	0.604849 (rank : 5)
Query Neighborhood Hits	63	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

DEN1A_HUMAN
θ value	2.13179e-17 (rank : 8)	NC score	0.601583 (rank : 6)
Query Neighborhood Hits	63	Target Neighborhood Hits	176	Shared Neighborhood Hits	19
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

ST5_HUMAN
θ value	3.07829e-16 (rank : 9)	NC score	0.559481 (rank : 10)
Query Neighborhood Hits	63	Target Neighborhood Hits	151	Shared Neighborhood Hits	18
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

ST5_MOUSE
θ value	3.07829e-16 (rank : 10)	NC score	0.562141 (rank : 9)
Query Neighborhood Hits	63	Target Neighborhood Hits	126	Shared Neighborhood Hits	18
SwissProt Accessions	Q924W7, Q78H54, Q8K2P3, Q924W8	Gene names	St5, Dennd2b
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (DENN domain-containing protein 2B).

DEN2A_MOUSE
θ value	1.86753e-13 (rank : 11)	NC score	0.558011 (rank : 12)
Query Neighborhood Hits	63	Target Neighborhood Hits	53	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C4S8, Q3TJU2, Q3TUG3, Q3UXA3	Gene names	Dennd2a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

DEN2C_HUMAN
θ value	5.43371e-13 (rank : 12)	NC score	0.558443 (rank : 11)
Query Neighborhood Hits	63	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q68D51, Q5TCX6, Q6P3R3	Gene names	DENND2C
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2C.

DEN2A_HUMAN
θ value	3.52202e-12 (rank : 13)	NC score	0.547147 (rank : 14)
Query Neighborhood Hits	63	Target Neighborhood Hits	83	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ULE3, Q1RMD5, Q86XY0	Gene names	DENND2A, KIAA1277
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

DEN2C_MOUSE
θ value	1.02475e-11 (rank : 14)	NC score	0.550453 (rank : 13)
Query Neighborhood Hits	63	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P9P8, Q3T9X2, Q3UV30, Q80V46	Gene names	Dennd2c
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2C.

DEN2D_MOUSE
θ value	1.74796e-11 (rank : 15)	NC score	0.574837 (rank : 7)
Query Neighborhood Hits	63	Target Neighborhood Hits	18	Shared Neighborhood Hits	16
SwissProt Accessions	Q91VV4, Q3U028, Q9D831	Gene names	Dennd2d
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2D.

DEN2D_HUMAN
θ value	1.9326e-10 (rank : 16)	NC score	0.571709 (rank : 8)
Query Neighborhood Hits	63	Target Neighborhood Hits	19	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H6A0, Q5T5V6, Q9BSU0	Gene names	DENND2D
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2D.

PK1L1_HUMAN
θ value	5.44631e-05 (rank : 17)	NC score	0.166795 (rank : 17)
Query Neighborhood Hits	63	Target Neighborhood Hits	140	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

RUFY3_HUMAN
θ value	0.000158464 (rank : 18)	NC score	0.146677 (rank : 19)
Query Neighborhood Hits	63	Target Neighborhood Hits	594	Shared Neighborhood Hits	18
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

RUFY3_MOUSE
θ value	0.00020696 (rank : 19)	NC score	0.147137 (rank : 18)
Query Neighborhood Hits	63	Target Neighborhood Hits	579	Shared Neighborhood Hits	18
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

RUFY1_MOUSE
θ value	0.00035302 (rank : 20)	NC score	0.115841 (rank : 20)
Query Neighborhood Hits	63	Target Neighborhood Hits	765	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

RUFY2_MOUSE
θ value	0.000461057 (rank : 21)	NC score	0.115722 (rank : 21)
Query Neighborhood Hits	63	Target Neighborhood Hits	820	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

RUFY1_HUMAN
θ value	0.000602161 (rank : 22)	NC score	0.112291 (rank : 22)
Query Neighborhood Hits	63	Target Neighborhood Hits	848	Shared Neighborhood Hits	16
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

RUFY2_HUMAN
θ value	0.00102713 (rank : 23)	NC score	0.089445 (rank : 25)
Query Neighborhood Hits	63	Target Neighborhood Hits	1208	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

PKDRE_MOUSE
θ value	0.0330416 (rank : 24)	NC score	0.102268 (rank : 23)
Query Neighborhood Hits	63	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

PKDRE_HUMAN
θ value	0.0736092 (rank : 25)	NC score	0.097460 (rank : 24)
Query Neighborhood Hits	63	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

PHOP2_HUMAN
θ value	0.125558 (rank : 26)	NC score	0.074037 (rank : 26)
Query Neighborhood Hits	63	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TCD6	Gene names	PHOSPHO2
Domain Architecture	No domain graphic available
Description	Pyridoxal phosphate phosphatase PHOSPHO2 (EC 3.1.3.74).

PKD1_HUMAN
θ value	0.125558 (rank : 27)	NC score	0.055955 (rank : 29)
Query Neighborhood Hits	63	Target Neighborhood Hits	387	Shared Neighborhood Hits	7
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

CCD41_MOUSE
θ value	0.21417 (rank : 28)	NC score	0.027940 (rank : 43)
Query Neighborhood Hits	63	Target Neighborhood Hits	1399	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

VAV_HUMAN
θ value	0.279714 (rank : 29)	NC score	0.014680 (rank : 60)
Query Neighborhood Hits	63	Target Neighborhood Hits	452	Shared Neighborhood Hits	6
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

SPTA1_HUMAN
θ value	0.62314 (rank : 30)	NC score	0.025004 (rank : 44)
Query Neighborhood Hits	63	Target Neighborhood Hits	748	Shared Neighborhood Hits	17
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

MYST2_HUMAN
θ value	0.813845 (rank : 31)	NC score	0.034385 (rank : 39)
Query Neighborhood Hits	63	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	O95251	Gene names	MYST2, HBO1, HBOa
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

MYST2_MOUSE
θ value	0.813845 (rank : 32)	NC score	0.034377 (rank : 40)
Query Neighborhood Hits	63	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	Q5SVQ0, Q5SVQ1, Q5SVQ2, Q5SVQ3, Q5SVQ7, Q6PGC6, Q80Y65	Gene names	Myst2, Hbo1
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

PEPL_MOUSE
θ value	0.813845 (rank : 33)	NC score	0.024312 (rank : 47)
Query Neighborhood Hits	63	Target Neighborhood Hits	1105	Shared Neighborhood Hits	18
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

CAPS1_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.036346 (rank : 37)
Query Neighborhood Hits	63	Target Neighborhood Hits	86	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULU8, Q13339, Q6GQQ6, Q8N2Z5, Q8N3M7, Q8NFR0, Q96BC2	Gene names	CADPS, CAPS, CAPS1, KIAA1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

CAPS1_MOUSE
θ value	1.81305 (rank : 35)	NC score	0.036319 (rank : 38)
Query Neighborhood Hits	63	Target Neighborhood Hits	93	Shared Neighborhood Hits	6
SwissProt Accessions	Q80TJ1, Q3TSP2, Q61374, Q6AXB4, Q6PGF0	Gene names	Cadps, Caps, Caps1, Kiaa1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

SNX5_HUMAN
θ value	1.81305 (rank : 36)	NC score	0.033423 (rank : 41)
Query Neighborhood Hits	63	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5X3, Q52LC4, Q9BWP0	Gene names	SNX5
Domain Architecture
Description	Sorting nexin-5.

K0226_MOUSE
θ value	2.36792 (rank : 37)	NC score	0.045451 (rank : 35)
Query Neighborhood Hits	63	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	Q80U62, Q3TAX3, Q3TDF7, Q3TDU2, Q6P9T7, Q6PG18, Q8BMP7, Q8BY22	Gene names	Kiaa0226
Domain Architecture	No domain graphic available
Description	Protein KIAA0226.

K0226_HUMAN
θ value	3.0926 (rank : 38)	NC score	0.043237 (rank : 36)
Query Neighborhood Hits	63	Target Neighborhood Hits	92	Shared Neighborhood Hits	7
SwissProt Accessions	Q92622	Gene names	KIAA0226
Domain Architecture	No domain graphic available
Description	Protein KIAA0226.

PTN23_MOUSE
θ value	3.0926 (rank : 39)	NC score	0.017619 (rank : 56)
Query Neighborhood Hits	63	Target Neighborhood Hits	726	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

SNX5_MOUSE
θ value	3.0926 (rank : 40)	NC score	0.029423 (rank : 42)
Query Neighborhood Hits	63	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D8U8, Q543N9	Gene names	Snx5
Domain Architecture
Description	Sorting nexin-5.

EP15_MOUSE
θ value	4.03905 (rank : 41)	NC score	0.019619 (rank : 53)
Query Neighborhood Hits	63	Target Neighborhood Hits	820	Shared Neighborhood Hits	17
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

LX12E_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.015627 (rank : 58)
Query Neighborhood Hits	63	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	P55249, Q91YW6	Gene names	Alox12e, Alox12-ps2, Aloxe
Domain Architecture
Description	Arachidonate 12-lipoxygenase, epidermal-type (EC 1.13.11.31) (12-LOX).

CCBP2_HUMAN
θ value	5.27518 (rank : 43)	NC score	0.002937 (rank : 69)
Query Neighborhood Hits	63	Target Neighborhood Hits	542	Shared Neighborhood Hits	3
SwissProt Accessions	O00590, O00537, Q86UN9, Q96A02	Gene names	CCBP2, CCR10, CMBRK9
Domain Architecture
Description	Chemokine-binding protein 2 (Chemokine-binding protein D6) (C-C chemokine receptor D6) (Chemokine receptor CCR-9) (Chemokine receptor CCR-10).

CO039_MOUSE
θ value	5.27518 (rank : 44)	NC score	0.022161 (rank : 51)
Query Neighborhood Hits	63	Target Neighborhood Hits	445	Shared Neighborhood Hits	6
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

DDX10_MOUSE
θ value	5.27518 (rank : 45)	NC score	0.004826 (rank : 68)
Query Neighborhood Hits	63	Target Neighborhood Hits	233	Shared Neighborhood Hits	4
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

UB2Q1_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.024557 (rank : 46)
Query Neighborhood Hits	63	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z7E8, Q3B841, Q5I0X2, Q6IS04, Q6P7P2, Q96MV4, Q9BVX5, Q9UGL6	Gene names	UBE2Q1, NICE5, UBE2Q
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 Q1 (EC 6.3.2.19) (Ubiquitin-protein ligase Q1) (Ubiquitin carrier protein Q1) (Protein NICE-5).

UB2Q1_MOUSE
θ value	5.27518 (rank : 47)	NC score	0.024310 (rank : 48)
Query Neighborhood Hits	63	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TSS2, Q3UIY3, Q6P913, Q80UT5, Q8K2T0, Q9D7E1	Gene names	Ube2q1, Ube2q
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 Q1 (EC 6.3.2.19) (Ubiquitin-protein ligase Q1) (Ubiquitin carrier protein Q1).

EPN3_MOUSE
θ value	6.88961 (rank : 48)	NC score	0.010467 (rank : 66)
Query Neighborhood Hits	63	Target Neighborhood Hits	312	Shared Neighborhood Hits	6
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

GOGB1_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.016610 (rank : 57)
Query Neighborhood Hits	63	Target Neighborhood Hits	2297	Shared Neighborhood Hits	25
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

IF3A_HUMAN
θ value	6.88961 (rank : 50)	NC score	0.018971 (rank : 54)
Query Neighborhood Hits	63	Target Neighborhood Hits	875	Shared Neighborhood Hits	17
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

IF3A_MOUSE
θ value	6.88961 (rank : 51)	NC score	0.018238 (rank : 55)
Query Neighborhood Hits	63	Target Neighborhood Hits	871	Shared Neighborhood Hits	15
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

MRE11_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.024979 (rank : 45)
Query Neighborhood Hits	63	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	P49959, O43475	Gene names	MRE11A, HNGS1, MRE11
Domain Architecture
Description	Double-strand break repair protein MRE11A (MRE11 homolog 1) (MRE11 meiotic recombination 11 homolog A).

NFAC1_MOUSE
θ value	6.88961 (rank : 53)	NC score	0.012162 (rank : 64)
Query Neighborhood Hits	63	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	O88942, O70345	Gene names	Nfatc1, Nfat2, Nfatc
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

RRMJ3_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.013254 (rank : 63)
Query Neighborhood Hits	63	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IY81, Q8N3A3, Q8WXX1, Q9BWM4, Q9NXT6	Gene names	FTSJ3
Domain Architecture	No domain graphic available
Description	Putative rRNA methyltransferase 3 (EC 2.1.1.-) (rRNA (uridine-2'-O-)- methyltransferase 3).

SLC2B_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.023034 (rank : 50)
Query Neighborhood Hits	63	Target Neighborhood Hits	214	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

AFF1_MOUSE
θ value	8.99809 (rank : 56)	NC score	0.010998 (rank : 65)
Query Neighborhood Hits	63	Target Neighborhood Hits	351	Shared Neighborhood Hits	5
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

AIM2_HUMAN
θ value	8.99809 (rank : 57)	NC score	0.015121 (rank : 59)
Query Neighborhood Hits	63	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	O14862	Gene names	AIM2
Domain Architecture
Description	Interferon-inducible protein AIM2 (Absent in melanoma 2).

BIN1_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.014052 (rank : 62)
Query Neighborhood Hits	63	Target Neighborhood Hits	335	Shared Neighborhood Hits	6
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

DBNL_MOUSE
θ value	8.99809 (rank : 59)	NC score	0.014312 (rank : 61)
Query Neighborhood Hits	63	Target Neighborhood Hits	306	Shared Neighborhood Hits	6
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

HEPH_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.006535 (rank : 67)
Query Neighborhood Hits	63	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BQS7, O75180, Q6UW45, Q9C058	Gene names	HEPH, KIAA0698
Domain Architecture	No domain graphic available
Description	Hephaestin precursor (EC 1.-.-.-).

MAP1A_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.023444 (rank : 49)
Query Neighborhood Hits	63	Target Neighborhood Hits	1626	Shared Neighborhood Hits	24
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MRE11_MOUSE
θ value	8.99809 (rank : 62)	NC score	0.021944 (rank : 52)
Query Neighborhood Hits	63	Target Neighborhood Hits	137	Shared Neighborhood Hits	7
SwissProt Accessions	Q61216, Q62430	Gene names	Mre11a, Mre11
Domain Architecture
Description	Double-strand break repair protein MRE11A (MRE11 homolog 1) (MRE11 meiotic recombination 11 homolog A) (MmMRE11A).

NEK11_HUMAN
θ value	8.99809 (rank : 63)	NC score	-0.002329 (rank : 70)
Query Neighborhood Hits	63	Target Neighborhood Hits	1043	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

MTMR2_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.051388 (rank : 33)
Query Neighborhood Hits	63	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q13614, Q9UPS9	Gene names	MTMR2, KIAA1073
Domain Architecture
Description	Myotubularin-related protein 2 (EC 3.1.3.-).

MTMR2_MOUSE
θ value	θ > 10 (rank : 65)	NC score	0.051500 (rank : 32)
Query Neighborhood Hits	63	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2D1, Q8VHA7	Gene names	Mtmr2
Domain Architecture
Description	Myotubularin-related protein 2 (EC 3.1.3.-).

MTMR3_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.071594 (rank : 27)
Query Neighborhood Hits	63	Target Neighborhood Hits	163	Shared Neighborhood Hits	6
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

MTMR3_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.057402 (rank : 28)
Query Neighborhood Hits	63	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K296	Gene names	Mtmr3
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48).

MTMR7_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.051537 (rank : 31)
Query Neighborhood Hits	63	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y216, Q68DX4	Gene names	MTMR7
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

MTMR7_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.051885 (rank : 30)
Query Neighborhood Hits	63	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2C9, Q8C4J6	Gene names	Mtmr7
Domain Architecture
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

MTMR9_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.050426 (rank : 34)
Query Neighborhood Hits	63	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2D0, Q80XL4	Gene names	Mtmr9, Mtmr3
Domain Architecture
Description	Myotubularin-related protein 9.

Hits sorted by NC score

RA6I1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	63	Target Neighborhood Hits	63	Shared Neighborhood Hits	63
SwissProt Accessions	Q6IQ26, Q96GN3, Q9H6U7, Q9UFV0, Q9UPR1	Gene names	RAB6IP1, KIAA1091
Domain Architecture	No domain graphic available
Description	Rab6-interacting protein 1 (Rab6IP1).

RA6I1_MOUSE
NC score	0.998895 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	63	Target Neighborhood Hits	57	Shared Neighborhood Hits	53
SwissProt Accessions	Q6PAL8, Q62146, Q8C829, Q8VDF6, Q9QYZ2	Gene names	Rab6ip1
Domain Architecture	No domain graphic available
Description	Rab6-interacting protein 1 (Rab6IP1).

MYCPP_HUMAN
NC score	0.686494 (rank : 3)	θ value	3.17079e-29 (rank : 4)
Query Neighborhood Hits	63	Target Neighborhood Hits	51	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z401, Q14655, Q86T77, Q8IVX2, Q8NB93	Gene names	MYCPBP, IRLB
Domain Architecture	No domain graphic available
Description	C-myc promoter-binding protein.

DEN4C_HUMAN
NC score	0.683970 (rank : 4)	θ value	3.17079e-29 (rank : 3)
Query Neighborhood Hits	63	Target Neighborhood Hits	63	Shared Neighborhood Hits	17
SwissProt Accessions	Q5VZ89, Q6AI48, Q6ZUB3, Q8NCY7, Q9H6N4, Q9NUT1, Q9NWA5	Gene names	DENND4C, C9orf55
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 4C.

DEN1A_MOUSE
NC score	0.604849 (rank : 5)	θ value	1.63225e-17 (rank : 7)
Query Neighborhood Hits	63	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

DEN1A_HUMAN
NC score	0.601583 (rank : 6)	θ value	2.13179e-17 (rank : 8)
Query Neighborhood Hits	63	Target Neighborhood Hits	176	Shared Neighborhood Hits	19
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

DEN2D_MOUSE
NC score	0.574837 (rank : 7)	θ value	1.74796e-11 (rank : 15)
Query Neighborhood Hits	63	Target Neighborhood Hits	18	Shared Neighborhood Hits	16
SwissProt Accessions	Q91VV4, Q3U028, Q9D831	Gene names	Dennd2d
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2D.

DEN2D_HUMAN
NC score	0.571709 (rank : 8)	θ value	1.9326e-10 (rank : 16)
Query Neighborhood Hits	63	Target Neighborhood Hits	19	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H6A0, Q5T5V6, Q9BSU0	Gene names	DENND2D
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2D.

ST5_MOUSE
NC score	0.562141 (rank : 9)	θ value	3.07829e-16 (rank : 10)
Query Neighborhood Hits	63	Target Neighborhood Hits	126	Shared Neighborhood Hits	18
SwissProt Accessions	Q924W7, Q78H54, Q8K2P3, Q924W8	Gene names	St5, Dennd2b
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (DENN domain-containing protein 2B).

ST5_HUMAN
NC score	0.559481 (rank : 10)	θ value	3.07829e-16 (rank : 9)
Query Neighborhood Hits	63	Target Neighborhood Hits	151	Shared Neighborhood Hits	18
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

DEN2C_HUMAN
NC score	0.558443 (rank : 11)	θ value	5.43371e-13 (rank : 12)
Query Neighborhood Hits	63	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q68D51, Q5TCX6, Q6P3R3	Gene names	DENND2C
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2C.

DEN2A_MOUSE
NC score	0.558011 (rank : 12)	θ value	1.86753e-13 (rank : 11)
Query Neighborhood Hits	63	Target Neighborhood Hits	53	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C4S8, Q3TJU2, Q3TUG3, Q3UXA3	Gene names	Dennd2a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

DEN2C_MOUSE
NC score	0.550453 (rank : 13)	θ value	1.02475e-11 (rank : 14)
Query Neighborhood Hits	63	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P9P8, Q3T9X2, Q3UV30, Q80V46	Gene names	Dennd2c
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2C.

DEN2A_HUMAN
NC score	0.547147 (rank : 14)	θ value	3.52202e-12 (rank : 13)
Query Neighborhood Hits	63	Target Neighborhood Hits	83	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ULE3, Q1RMD5, Q86XY0	Gene names	DENND2A, KIAA1277
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

MTMR5_HUMAN
NC score	0.482008 (rank : 15)	θ value	1.6852e-22 (rank : 5)
Query Neighborhood Hits	63	Target Neighborhood Hits	141	Shared Neighborhood Hits	16
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

MTMRD_HUMAN
NC score	0.479199 (rank : 16)	θ value	1.86321e-21 (rank : 6)
Query Neighborhood Hits	63	Target Neighborhood Hits	135	Shared Neighborhood Hits	16
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

PK1L1_HUMAN
NC score	0.166795 (rank : 17)	θ value	5.44631e-05 (rank : 17)
Query Neighborhood Hits	63	Target Neighborhood Hits	140	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

RUFY3_MOUSE
NC score	0.147137 (rank : 18)	θ value	0.00020696 (rank : 19)
Query Neighborhood Hits	63	Target Neighborhood Hits	579	Shared Neighborhood Hits	18
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

RUFY3_HUMAN
NC score	0.146677 (rank : 19)	θ value	0.000158464 (rank : 18)
Query Neighborhood Hits	63	Target Neighborhood Hits	594	Shared Neighborhood Hits	18
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

RUFY1_MOUSE
NC score	0.115841 (rank : 20)	θ value	0.00035302 (rank : 20)
Query Neighborhood Hits	63	Target Neighborhood Hits	765	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

RUFY2_MOUSE
NC score	0.115722 (rank : 21)	θ value	0.000461057 (rank : 21)
Query Neighborhood Hits	63	Target Neighborhood Hits	820	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

RUFY1_HUMAN
NC score	0.112291 (rank : 22)	θ value	0.000602161 (rank : 22)
Query Neighborhood Hits	63	Target Neighborhood Hits	848	Shared Neighborhood Hits	16
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

PKDRE_MOUSE
NC score	0.102268 (rank : 23)	θ value	0.0330416 (rank : 24)
Query Neighborhood Hits	63	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

PKDRE_HUMAN
NC score	0.097460 (rank : 24)	θ value	0.0736092 (rank : 25)
Query Neighborhood Hits	63	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

RUFY2_HUMAN
NC score	0.089445 (rank : 25)	θ value	0.00102713 (rank : 23)
Query Neighborhood Hits	63	Target Neighborhood Hits	1208	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

PHOP2_HUMAN
NC score	0.074037 (rank : 26)	θ value	0.125558 (rank : 26)
Query Neighborhood Hits	63	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TCD6	Gene names	PHOSPHO2
Domain Architecture	No domain graphic available
Description	Pyridoxal phosphate phosphatase PHOSPHO2 (EC 3.1.3.74).

MTMR3_HUMAN
NC score	0.071594 (rank : 27)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	63	Target Neighborhood Hits	163	Shared Neighborhood Hits	6
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

MTMR3_MOUSE
NC score	0.057402 (rank : 28)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	63	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K296	Gene names	Mtmr3
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48).

PKD1_HUMAN
NC score	0.055955 (rank : 29)	θ value	0.125558 (rank : 27)
Query Neighborhood Hits	63	Target Neighborhood Hits	387	Shared Neighborhood Hits	7
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

MTMR7_MOUSE
NC score	0.051885 (rank : 30)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	63	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2C9, Q8C4J6	Gene names	Mtmr7
Domain Architecture
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

MTMR7_HUMAN
NC score	0.051537 (rank : 31)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	63	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y216, Q68DX4	Gene names	MTMR7
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

MTMR2_MOUSE
NC score	0.051500 (rank : 32)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	63	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2D1, Q8VHA7	Gene names	Mtmr2
Domain Architecture
Description	Myotubularin-related protein 2 (EC 3.1.3.-).

MTMR2_HUMAN
NC score	0.051388 (rank : 33)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	63	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q13614, Q9UPS9	Gene names	MTMR2, KIAA1073
Domain Architecture
Description	Myotubularin-related protein 2 (EC 3.1.3.-).

MTMR9_MOUSE
NC score	0.050426 (rank : 34)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	63	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2D0, Q80XL4	Gene names	Mtmr9, Mtmr3
Domain Architecture
Description	Myotubularin-related protein 9.

K0226_MOUSE
NC score	0.045451 (rank : 35)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	63	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	Q80U62, Q3TAX3, Q3TDF7, Q3TDU2, Q6P9T7, Q6PG18, Q8BMP7, Q8BY22	Gene names	Kiaa0226
Domain Architecture	No domain graphic available
Description	Protein KIAA0226.

K0226_HUMAN
NC score	0.043237 (rank : 36)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	63	Target Neighborhood Hits	92	Shared Neighborhood Hits	7
SwissProt Accessions	Q92622	Gene names	KIAA0226
Domain Architecture	No domain graphic available
Description	Protein KIAA0226.

CAPS1_HUMAN
NC score	0.036346 (rank : 37)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	63	Target Neighborhood Hits	86	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULU8, Q13339, Q6GQQ6, Q8N2Z5, Q8N3M7, Q8NFR0, Q96BC2	Gene names	CADPS, CAPS, CAPS1, KIAA1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

CAPS1_MOUSE
NC score	0.036319 (rank : 38)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	63	Target Neighborhood Hits	93	Shared Neighborhood Hits	6
SwissProt Accessions	Q80TJ1, Q3TSP2, Q61374, Q6AXB4, Q6PGF0	Gene names	Cadps, Caps, Caps1, Kiaa1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

MYST2_HUMAN
NC score	0.034385 (rank : 39)	θ value	0.813845 (rank : 31)
Query Neighborhood Hits	63	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	O95251	Gene names	MYST2, HBO1, HBOa
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

MYST2_MOUSE
NC score	0.034377 (rank : 40)	θ value	0.813845 (rank : 32)
Query Neighborhood Hits	63	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	Q5SVQ0, Q5SVQ1, Q5SVQ2, Q5SVQ3, Q5SVQ7, Q6PGC6, Q80Y65	Gene names	Myst2, Hbo1
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

SNX5_HUMAN
NC score	0.033423 (rank : 41)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	63	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5X3, Q52LC4, Q9BWP0	Gene names	SNX5
Domain Architecture
Description	Sorting nexin-5.

SNX5_MOUSE
NC score	0.029423 (rank : 42)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	63	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D8U8, Q543N9	Gene names	Snx5
Domain Architecture
Description	Sorting nexin-5.

CCD41_MOUSE
NC score	0.027940 (rank : 43)	θ value	0.21417 (rank : 28)
Query Neighborhood Hits	63	Target Neighborhood Hits	1399	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

SPTA1_HUMAN
NC score	0.025004 (rank : 44)	θ value	0.62314 (rank : 30)
Query Neighborhood Hits	63	Target Neighborhood Hits	748	Shared Neighborhood Hits	17
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

MRE11_HUMAN
NC score	0.024979 (rank : 45)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	63	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	P49959, O43475	Gene names	MRE11A, HNGS1, MRE11
Domain Architecture
Description	Double-strand break repair protein MRE11A (MRE11 homolog 1) (MRE11 meiotic recombination 11 homolog A).

UB2Q1_HUMAN
NC score	0.024557 (rank : 46)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	63	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z7E8, Q3B841, Q5I0X2, Q6IS04, Q6P7P2, Q96MV4, Q9BVX5, Q9UGL6	Gene names	UBE2Q1, NICE5, UBE2Q
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 Q1 (EC 6.3.2.19) (Ubiquitin-protein ligase Q1) (Ubiquitin carrier protein Q1) (Protein NICE-5).

PEPL_MOUSE
NC score	0.024312 (rank : 47)	θ value	0.813845 (rank : 33)
Query Neighborhood Hits	63	Target Neighborhood Hits	1105	Shared Neighborhood Hits	18
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

UB2Q1_MOUSE
NC score	0.024310 (rank : 48)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	63	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TSS2, Q3UIY3, Q6P913, Q80UT5, Q8K2T0, Q9D7E1	Gene names	Ube2q1, Ube2q
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 Q1 (EC 6.3.2.19) (Ubiquitin-protein ligase Q1) (Ubiquitin carrier protein Q1).

MAP1A_HUMAN
NC score	0.023444 (rank : 49)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	63	Target Neighborhood Hits	1626	Shared Neighborhood Hits	24
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

SLC2B_HUMAN
NC score	0.023034 (rank : 50)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	63	Target Neighborhood Hits	214	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

CO039_MOUSE
NC score	0.022161 (rank : 51)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	63	Target Neighborhood Hits	445	Shared Neighborhood Hits	6
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

MRE11_MOUSE
NC score	0.021944 (rank : 52)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	63	Target Neighborhood Hits	137	Shared Neighborhood Hits	7
SwissProt Accessions	Q61216, Q62430	Gene names	Mre11a, Mre11
Domain Architecture
Description	Double-strand break repair protein MRE11A (MRE11 homolog 1) (MRE11 meiotic recombination 11 homolog A) (MmMRE11A).

EP15_MOUSE
NC score	0.019619 (rank : 53)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	63	Target Neighborhood Hits	820	Shared Neighborhood Hits	17
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

IF3A_HUMAN
NC score	0.018971 (rank : 54)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	63	Target Neighborhood Hits	875	Shared Neighborhood Hits	17
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

IF3A_MOUSE
NC score	0.018238 (rank : 55)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	63	Target Neighborhood Hits	871	Shared Neighborhood Hits	15
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

PTN23_MOUSE
NC score	0.017619 (rank : 56)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	63	Target Neighborhood Hits	726	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

GOGB1_HUMAN
NC score	0.016610 (rank : 57)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	63	Target Neighborhood Hits	2297	Shared Neighborhood Hits	25
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

LX12E_MOUSE
NC score	0.015627 (rank : 58)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	63	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	P55249, Q91YW6	Gene names	Alox12e, Alox12-ps2, Aloxe
Domain Architecture
Description	Arachidonate 12-lipoxygenase, epidermal-type (EC 1.13.11.31) (12-LOX).

AIM2_HUMAN
NC score	0.015121 (rank : 59)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	63	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	O14862	Gene names	AIM2
Domain Architecture
Description	Interferon-inducible protein AIM2 (Absent in melanoma 2).

VAV_HUMAN
NC score	0.014680 (rank : 60)	θ value	0.279714 (rank : 29)
Query Neighborhood Hits	63	Target Neighborhood Hits	452	Shared Neighborhood Hits	6
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

DBNL_MOUSE
NC score	0.014312 (rank : 61)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	63	Target Neighborhood Hits	306	Shared Neighborhood Hits	6
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

BIN1_HUMAN
NC score	0.014052 (rank : 62)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	63	Target Neighborhood Hits	335	Shared Neighborhood Hits	6
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

RRMJ3_HUMAN
NC score	0.013254 (rank : 63)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	63	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IY81, Q8N3A3, Q8WXX1, Q9BWM4, Q9NXT6	Gene names	FTSJ3
Domain Architecture	No domain graphic available
Description	Putative rRNA methyltransferase 3 (EC 2.1.1.-) (rRNA (uridine-2'-O-)- methyltransferase 3).

NFAC1_MOUSE
NC score	0.012162 (rank : 64)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	63	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	O88942, O70345	Gene names	Nfatc1, Nfat2, Nfatc
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

AFF1_MOUSE
NC score	0.010998 (rank : 65)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	63	Target Neighborhood Hits	351	Shared Neighborhood Hits	5
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

EPN3_MOUSE
NC score	0.010467 (rank : 66)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	63	Target Neighborhood Hits	312	Shared Neighborhood Hits	6
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

HEPH_HUMAN
NC score	0.006535 (rank : 67)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	63	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BQS7, O75180, Q6UW45, Q9C058	Gene names	HEPH, KIAA0698
Domain Architecture	No domain graphic available
Description	Hephaestin precursor (EC 1.-.-.-).

DDX10_MOUSE
NC score	0.004826 (rank : 68)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	63	Target Neighborhood Hits	233	Shared Neighborhood Hits	4
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

CCBP2_HUMAN
NC score	0.002937 (rank : 69)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	63	Target Neighborhood Hits	542	Shared Neighborhood Hits	3
SwissProt Accessions	O00590, O00537, Q86UN9, Q96A02	Gene names	CCBP2, CCR10, CMBRK9
Domain Architecture
Description	Chemokine-binding protein 2 (Chemokine-binding protein D6) (C-C chemokine receptor D6) (Chemokine receptor CCR-9) (Chemokine receptor CCR-10).

NEK11_HUMAN
NC score	-0.002329 (rank : 70)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	63	Target Neighborhood Hits	1043	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).