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Network neighborhood for query Sequence : DEN2D_HUMAN

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DEN2D_HUMAN
SwissProt Accessions	Q9H6A0, Q5T5V6, Q9BSU0	Gene names	DENND2D
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2D.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DEN2D_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H6A0, Q5T5V6, Q9BSU0	Gene names	DENND2D
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2D.

DEN2D_MOUSE
θ value	0 (rank : 2)	NC score	0.999484 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	16
SwissProt Accessions	Q91VV4, Q3U028, Q9D831	Gene names	Dennd2d
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2D.

ST5_HUMAN
θ value	8.99321e-117 (rank : 3)	NC score	0.956434 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	151	Shared Neighborhood Hits	16
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

ST5_MOUSE
θ value	2.00348e-116 (rank : 4)	NC score	0.959126 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	126	Shared Neighborhood Hits	16
SwissProt Accessions	Q924W7, Q78H54, Q8K2P3, Q924W8	Gene names	St5, Dennd2b
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (DENN domain-containing protein 2B).

DEN2C_HUMAN
θ value	7.37397e-111 (rank : 5)	NC score	0.969173 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q68D51, Q5TCX6, Q6P3R3	Gene names	DENND2C
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2C.

DEN2C_MOUSE
θ value	4.1872e-106 (rank : 6)	NC score	0.968684 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P9P8, Q3T9X2, Q3UV30, Q80V46	Gene names	Dennd2c
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2C.

DEN2A_HUMAN
θ value	1.88391e-98 (rank : 7)	NC score	0.960490 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	83	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ULE3, Q1RMD5, Q86XY0	Gene names	DENND2A, KIAA1277
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

DEN2A_MOUSE
θ value	7.15887e-98 (rank : 8)	NC score	0.966054 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	53	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C4S8, Q3TJU2, Q3TUG3, Q3UXA3	Gene names	Dennd2a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

DEN1A_MOUSE
θ value	1.32909e-35 (rank : 9)	NC score	0.817848 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

DEN1A_HUMAN
θ value	2.96089e-35 (rank : 10)	NC score	0.812806 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	176	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

MYCPP_HUMAN
θ value	8.10077e-17 (rank : 11)	NC score	0.617137 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	51	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z401, Q14655, Q86T77, Q8IVX2, Q8NB93	Gene names	MYCPBP, IRLB
Domain Architecture	No domain graphic available
Description	C-myc promoter-binding protein.

DEN4C_HUMAN
θ value	8.38298e-14 (rank : 12)	NC score	0.593713 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	63	Shared Neighborhood Hits	16
SwissProt Accessions	Q5VZ89, Q6AI48, Q6ZUB3, Q8NCY7, Q9H6N4, Q9NUT1, Q9NWA5	Gene names	DENND4C, C9orf55
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 4C.

MTMR5_HUMAN
θ value	3.18553e-13 (rank : 13)	NC score	0.445246 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	141	Shared Neighborhood Hits	16
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

MTMRD_HUMAN
θ value	1.02475e-11 (rank : 14)	NC score	0.444454 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	135	Shared Neighborhood Hits	16
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

RA6I1_HUMAN
θ value	1.9326e-10 (rank : 15)	NC score	0.571709 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	63	Shared Neighborhood Hits	16
SwissProt Accessions	Q6IQ26, Q96GN3, Q9H6U7, Q9UFV0, Q9UPR1	Gene names	RAB6IP1, KIAA1091
Domain Architecture	No domain graphic available
Description	Rab6-interacting protein 1 (Rab6IP1).

RA6I1_MOUSE
θ value	1.9326e-10 (rank : 16)	NC score	0.572372 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	57	Shared Neighborhood Hits	16
SwissProt Accessions	Q6PAL8, Q62146, Q8C829, Q8VDF6, Q9QYZ2	Gene names	Rab6ip1
Domain Architecture	No domain graphic available
Description	Rab6-interacting protein 1 (Rab6IP1).

CUL2_MOUSE
θ value	1.81305 (rank : 17)	NC score	0.011446 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D4H8, Q3TUR8	Gene names	Cul2
Domain Architecture
Description	Cullin-2 (CUL-2).

IDE_HUMAN
θ value	3.0926 (rank : 18)	NC score	0.012451 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	P14735	Gene names	IDE
Domain Architecture
Description	Insulin-degrading enzyme (EC 3.4.24.56) (Insulysin) (Insulinase) (Insulin protease).

DDX11_MOUSE
θ value	6.88961 (rank : 19)	NC score	0.007805 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q6AXC6	Gene names	Ddx11
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX11 (EC 3.6.1.-) (DEAD/H box protein 11).

Hits sorted by NC score

DEN2D_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H6A0, Q5T5V6, Q9BSU0	Gene names	DENND2D
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2D.

DEN2D_MOUSE
NC score	0.999484 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	16
SwissProt Accessions	Q91VV4, Q3U028, Q9D831	Gene names	Dennd2d
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2D.

DEN2C_HUMAN
NC score	0.969173 (rank : 3)	θ value	7.37397e-111 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q68D51, Q5TCX6, Q6P3R3	Gene names	DENND2C
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2C.

DEN2C_MOUSE
NC score	0.968684 (rank : 4)	θ value	4.1872e-106 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P9P8, Q3T9X2, Q3UV30, Q80V46	Gene names	Dennd2c
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2C.

DEN2A_MOUSE
NC score	0.966054 (rank : 5)	θ value	7.15887e-98 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	53	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C4S8, Q3TJU2, Q3TUG3, Q3UXA3	Gene names	Dennd2a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

DEN2A_HUMAN
NC score	0.960490 (rank : 6)	θ value	1.88391e-98 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	83	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ULE3, Q1RMD5, Q86XY0	Gene names	DENND2A, KIAA1277
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

ST5_MOUSE
NC score	0.959126 (rank : 7)	θ value	2.00348e-116 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	126	Shared Neighborhood Hits	16
SwissProt Accessions	Q924W7, Q78H54, Q8K2P3, Q924W8	Gene names	St5, Dennd2b
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (DENN domain-containing protein 2B).

ST5_HUMAN
NC score	0.956434 (rank : 8)	θ value	8.99321e-117 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	151	Shared Neighborhood Hits	16
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

DEN1A_MOUSE
NC score	0.817848 (rank : 9)	θ value	1.32909e-35 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

DEN1A_HUMAN
NC score	0.812806 (rank : 10)	θ value	2.96089e-35 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	176	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

MYCPP_HUMAN
NC score	0.617137 (rank : 11)	θ value	8.10077e-17 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	51	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z401, Q14655, Q86T77, Q8IVX2, Q8NB93	Gene names	MYCPBP, IRLB
Domain Architecture	No domain graphic available
Description	C-myc promoter-binding protein.

DEN4C_HUMAN
NC score	0.593713 (rank : 12)	θ value	8.38298e-14 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	63	Shared Neighborhood Hits	16
SwissProt Accessions	Q5VZ89, Q6AI48, Q6ZUB3, Q8NCY7, Q9H6N4, Q9NUT1, Q9NWA5	Gene names	DENND4C, C9orf55
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 4C.

RA6I1_MOUSE
NC score	0.572372 (rank : 13)	θ value	1.9326e-10 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	57	Shared Neighborhood Hits	16
SwissProt Accessions	Q6PAL8, Q62146, Q8C829, Q8VDF6, Q9QYZ2	Gene names	Rab6ip1
Domain Architecture	No domain graphic available
Description	Rab6-interacting protein 1 (Rab6IP1).

RA6I1_HUMAN
NC score	0.571709 (rank : 14)	θ value	1.9326e-10 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	63	Shared Neighborhood Hits	16
SwissProt Accessions	Q6IQ26, Q96GN3, Q9H6U7, Q9UFV0, Q9UPR1	Gene names	RAB6IP1, KIAA1091
Domain Architecture	No domain graphic available
Description	Rab6-interacting protein 1 (Rab6IP1).

MTMR5_HUMAN
NC score	0.445246 (rank : 15)	θ value	3.18553e-13 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	141	Shared Neighborhood Hits	16
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

MTMRD_HUMAN
NC score	0.444454 (rank : 16)	θ value	1.02475e-11 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	135	Shared Neighborhood Hits	16
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

IDE_HUMAN
NC score	0.012451 (rank : 17)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	P14735	Gene names	IDE
Domain Architecture
Description	Insulin-degrading enzyme (EC 3.4.24.56) (Insulysin) (Insulinase) (Insulin protease).

CUL2_MOUSE
NC score	0.011446 (rank : 18)	θ value	1.81305 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D4H8, Q3TUR8	Gene names	Cul2
Domain Architecture
Description	Cullin-2 (CUL-2).

DDX11_MOUSE
NC score	0.007805 (rank : 19)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q6AXC6	Gene names	Ddx11
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX11 (EC 3.6.1.-) (DEAD/H box protein 11).