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Network neighborhood for query Sequence : HEM1_MOUSE

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HEM1_MOUSE
SwissProt Accessions	Q8VC19, Q64453	Gene names	Alas1
Domain Architecture	No domain graphic available
Description	5-aminolevulinate synthase, nonspecific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-H).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HEM0_HUMAN
θ value	0 (rank : 1)	NC score	0.984095 (rank : 4)
Query Neighborhood Hits	66	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	P22557, Q13735	Gene names	ALAS2, ALASE, ASB
Domain Architecture
Description	5-aminolevulinate synthase, erythroid-specific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta- aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-E).

HEM0_MOUSE
θ value	0 (rank : 2)	NC score	0.984305 (rank : 3)
Query Neighborhood Hits	66	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	P08680, Q64452, Q9DCN0	Gene names	Alas2
Domain Architecture
Description	5-aminolevulinate synthase, erythroid-specific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta- aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-E).

HEM1_HUMAN
θ value	0 (rank : 3)	NC score	0.990798 (rank : 2)
Query Neighborhood Hits	66	Target Neighborhood Hits	45	Shared Neighborhood Hits	17
SwissProt Accessions	P13196	Gene names	ALAS1, ALASH
Domain Architecture
Description	5-aminolevulinate synthase, nonspecific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-H).

HEM1_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	66	Target Neighborhood Hits	66	Shared Neighborhood Hits	66
SwissProt Accessions	Q8VC19, Q64453	Gene names	Alas1
Domain Architecture	No domain graphic available
Description	5-aminolevulinate synthase, nonspecific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-H).

KBL_MOUSE
θ value	8.28633e-54 (rank : 5)	NC score	0.893235 (rank : 5)
Query Neighborhood Hits	66	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	O88986	Gene names	Gcat, Kbl
Domain Architecture
Description	2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial precursor (EC 2.3.1.29) (AKB ligase) (Glycine acetyltransferase).

KBL_HUMAN
θ value	2.3352e-48 (rank : 6)	NC score	0.889807 (rank : 6)
Query Neighborhood Hits	66	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	O75600, Q96CA9	Gene names	GCAT, KBL
Domain Architecture
Description	2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial precursor (EC 2.3.1.29) (AKB ligase) (Glycine acetyltransferase).

LCB2_MOUSE
θ value	4.88048e-38 (rank : 7)	NC score	0.813930 (rank : 7)
Query Neighborhood Hits	66	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	P97363, P97356	Gene names	Sptlc2, Lcb2
Domain Architecture
Description	Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Serine-palmitoyl-CoA transferase 2) (SPT 2).

LCB2_HUMAN
θ value	1.20211e-36 (rank : 8)	NC score	0.811708 (rank : 8)
Query Neighborhood Hits	66	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	O15270, Q16685	Gene names	SPTLC2, KIAA0526, LCB2
Domain Architecture
Description	Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Serine-palmitoyl-CoA transferase 2) (SPT 2).

LCB1_MOUSE
θ value	4.01107e-24 (rank : 9)	NC score	0.774564 (rank : 9)
Query Neighborhood Hits	66	Target Neighborhood Hits	22	Shared Neighborhood Hits	10
SwissProt Accessions	O35704, O54813	Gene names	Sptlc1, Lcb1
Domain Architecture
Description	Serine palmitoyltransferase 1 (EC 2.3.1.50) (Long chain base biosynthesis protein 1) (LCB 1) (Serine-palmitoyl-CoA transferase 1) (SPT 1) (SPT1).

LCB1_HUMAN
θ value	8.93572e-24 (rank : 10)	NC score	0.772738 (rank : 10)
Query Neighborhood Hits	66	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	O15269	Gene names	SPTLC1, LCB1
Domain Architecture
Description	Serine palmitoyltransferase 1 (EC 2.3.1.50) (Long chain base biosynthesis protein 1) (LCB 1) (Serine-palmitoyl-CoA transferase 1) (SPT 1) (SPT1).

CCD37_HUMAN
θ value	0.0113563 (rank : 11)	NC score	0.047332 (rank : 12)
Query Neighborhood Hits	66	Target Neighborhood Hits	248	Shared Neighborhood Hits	3
SwissProt Accessions	Q494V2, Q494V1, Q494V4, Q8N838	Gene names	CCDC37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

SRRM2_HUMAN
θ value	0.0148317 (rank : 12)	NC score	0.041236 (rank : 13)
Query Neighborhood Hits	66	Target Neighborhood Hits	1296	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

PCLO_MOUSE
θ value	0.163984 (rank : 13)	NC score	0.021428 (rank : 34)
Query Neighborhood Hits	66	Target Neighborhood Hits	2275	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

CEP57_HUMAN
θ value	0.21417 (rank : 14)	NC score	0.025604 (rank : 24)
Query Neighborhood Hits	66	Target Neighborhood Hits	576	Shared Neighborhood Hits	4
SwissProt Accessions	Q86XR8, Q14704, Q8IXP0, Q9BVF9	Gene names	CEP57, KIAA0092, TSP57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin) (FGF2-interacting protein).

DAB1_MOUSE
θ value	0.21417 (rank : 15)	NC score	0.039543 (rank : 14)
Query Neighborhood Hits	66	Target Neighborhood Hits	145	Shared Neighborhood Hits	11
SwissProt Accessions	P97318, P97316, P97317	Gene names	Dab1
Domain Architecture
Description	Disabled homolog 1.

NIT1_HUMAN
θ value	0.47712 (rank : 16)	NC score	0.034959 (rank : 17)
Query Neighborhood Hits	66	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q86X76, O76091	Gene names	NIT1
Domain Architecture
Description	Nitrilase homolog 1 (EC 3.5.-.-).

RERE_MOUSE
θ value	0.62314 (rank : 17)	NC score	0.029869 (rank : 21)
Query Neighborhood Hits	66	Target Neighborhood Hits	785	Shared Neighborhood Hits	22
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

TXND2_HUMAN
θ value	0.62314 (rank : 18)	NC score	0.024122 (rank : 25)
Query Neighborhood Hits	66	Target Neighborhood Hits	793	Shared Neighborhood Hits	20
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

ATE1_HUMAN
θ value	0.813845 (rank : 19)	NC score	0.035472 (rank : 16)
Query Neighborhood Hits	66	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	O95260, O95261, Q8WW04	Gene names	ATE1
Domain Architecture
Description	Arginyl-tRNA--protein transferase 1 (EC 2.3.2.8) (R-transferase 1) (Arginyltransferase 1) (Arginine-tRNA--protein transferase 1).

ATX2L_HUMAN
θ value	0.813845 (rank : 20)	NC score	0.035621 (rank : 15)
Query Neighborhood Hits	66	Target Neighborhood Hits	443	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

FA13C_HUMAN
θ value	0.813845 (rank : 21)	NC score	0.023322 (rank : 29)
Query Neighborhood Hits	66	Target Neighborhood Hits	94	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

MTMR3_HUMAN
θ value	0.813845 (rank : 22)	NC score	0.013613 (rank : 49)
Query Neighborhood Hits	66	Target Neighborhood Hits	163	Shared Neighborhood Hits	3
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

ROBO3_HUMAN
θ value	0.813845 (rank : 23)	NC score	0.006939 (rank : 59)
Query Neighborhood Hits	66	Target Neighborhood Hits	570	Shared Neighborhood Hits	11
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

BMP2K_HUMAN
θ value	1.06291 (rank : 24)	NC score	0.004332 (rank : 63)
Query Neighborhood Hits	66	Target Neighborhood Hits	867	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NSY1, O94791, Q8IYF2, Q8N2G7, Q8NHG9, Q9NTG8	Gene names	BMP2K, BIKE
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

CBP_HUMAN
θ value	1.06291 (rank : 25)	NC score	0.021683 (rank : 33)
Query Neighborhood Hits	66	Target Neighborhood Hits	941	Shared Neighborhood Hits	22
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

RCN1_MOUSE
θ value	1.06291 (rank : 26)	NC score	0.021036 (rank : 35)
Query Neighborhood Hits	66	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	Q05186, Q3TVU3	Gene names	Rcn1, Rca1, Rcn
Domain Architecture
Description	Reticulocalbin-1 precursor.

ATX2L_MOUSE
θ value	1.38821 (rank : 27)	NC score	0.032062 (rank : 19)
Query Neighborhood Hits	66	Target Neighborhood Hits	401	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

BAT2_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.023810 (rank : 27)
Query Neighborhood Hits	66	Target Neighborhood Hits	931	Shared Neighborhood Hits	25
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

REXO4_HUMAN
θ value	1.38821 (rank : 29)	NC score	0.023478 (rank : 28)
Query Neighborhood Hits	66	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9GZR2, Q5T8S4, Q5T8S5, Q5T8S6, Q9GZW3	Gene names	REXO4, PMC2, XPMC2H
Domain Architecture	No domain graphic available
Description	RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (hPMC2) (Prevents mitotic catastrophe 2 protein homolog).

WDR46_MOUSE
θ value	1.38821 (rank : 30)	NC score	0.024018 (rank : 26)
Query Neighborhood Hits	66	Target Neighborhood Hits	243	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

MAP4_MOUSE
θ value	1.81305 (rank : 31)	NC score	0.027210 (rank : 23)
Query Neighborhood Hits	66	Target Neighborhood Hits	409	Shared Neighborhood Hits	15
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

NCOA6_HUMAN
θ value	1.81305 (rank : 32)	NC score	0.022257 (rank : 31)
Query Neighborhood Hits	66	Target Neighborhood Hits	1202	Shared Neighborhood Hits	26
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

SRRM2_MOUSE
θ value	1.81305 (rank : 33)	NC score	0.032170 (rank : 18)
Query Neighborhood Hits	66	Target Neighborhood Hits	1470	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ATN1_HUMAN
θ value	2.36792 (rank : 34)	NC score	0.028390 (rank : 22)
Query Neighborhood Hits	66	Target Neighborhood Hits	676	Shared Neighborhood Hits	18
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

INGR1_MOUSE
θ value	2.36792 (rank : 35)	NC score	0.022422 (rank : 30)
Query Neighborhood Hits	66	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	P15261	Gene names	Ifngr1, Ifngr
Domain Architecture
Description	Interferon-gamma receptor alpha chain precursor (IFN-gamma-R1) (CD119 antigen).

LMBL3_MOUSE
θ value	2.36792 (rank : 36)	NC score	0.015418 (rank : 43)
Query Neighborhood Hits	66	Target Neighborhood Hits	212	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BLB7, Q641L7, Q6ZPI2, Q8C0G4	Gene names	L3mbtl3
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein).

STK39_MOUSE
θ value	2.36792 (rank : 37)	NC score	0.000040 (rank : 66)
Query Neighborhood Hits	66	Target Neighborhood Hits	915	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1W9, Q80W13	Gene names	Stk39, Spak
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39).

IF35_HUMAN
θ value	3.0926 (rank : 38)	NC score	0.017075 (rank : 40)
Query Neighborhood Hits	66	Target Neighborhood Hits	130	Shared Neighborhood Hits	4
SwissProt Accessions	O00303, Q8N978	Gene names	EIF3S5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

MYO9B_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.005653 (rank : 60)
Query Neighborhood Hits	66	Target Neighborhood Hits	641	Shared Neighborhood Hits	15
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

RCN1_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.017983 (rank : 38)
Query Neighborhood Hits	66	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	Q15293	Gene names	RCN1, RCN
Domain Architecture
Description	Reticulocalbin-1 precursor.

TGON2_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.019302 (rank : 36)
Query Neighborhood Hits	66	Target Neighborhood Hits	1037	Shared Neighborhood Hits	23
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

UBP42_HUMAN
θ value	3.0926 (rank : 42)	NC score	0.012250 (rank : 51)
Query Neighborhood Hits	66	Target Neighborhood Hits	445	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

3BP2_MOUSE
θ value	4.03905 (rank : 43)	NC score	0.014905 (rank : 44)
Query Neighborhood Hits	66	Target Neighborhood Hits	142	Shared Neighborhood Hits	4
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

CEP57_MOUSE
θ value	4.03905 (rank : 44)	NC score	0.018399 (rank : 37)
Query Neighborhood Hits	66	Target Neighborhood Hits	580	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

DAB1_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.030891 (rank : 20)
Query Neighborhood Hits	66	Target Neighborhood Hits	219	Shared Neighborhood Hits	12
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

ENAH_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.014610 (rank : 45)
Query Neighborhood Hits	66	Target Neighborhood Hits	784	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

EPHB3_MOUSE
θ value	5.27518 (rank : 47)	NC score	-0.000673 (rank : 67)
Query Neighborhood Hits	66	Target Neighborhood Hits	996	Shared Neighborhood Hits	5
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

HTSF1_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.010600 (rank : 55)
Query Neighborhood Hits	66	Target Neighborhood Hits	408	Shared Neighborhood Hits	5
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

MAP4_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.021774 (rank : 32)
Query Neighborhood Hits	66	Target Neighborhood Hits	428	Shared Neighborhood Hits	14
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

PO6F2_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.011867 (rank : 53)
Query Neighborhood Hits	66	Target Neighborhood Hits	618	Shared Neighborhood Hits	15
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

TACC3_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.010717 (rank : 54)
Query Neighborhood Hits	66	Target Neighborhood Hits	779	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

CCD55_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.007920 (rank : 58)
Query Neighborhood Hits	66	Target Neighborhood Hits	513	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CJ047_MOUSE
θ value	6.88961 (rank : 53)	NC score	0.014403 (rank : 46)
Query Neighborhood Hits	66	Target Neighborhood Hits	76	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C5R2, Q8R017, Q8R2Z9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf47 homolog.

GLGB_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.017185 (rank : 39)
Query Neighborhood Hits	66	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q04446, Q96EN0	Gene names	GBE1
Domain Architecture
Description	1,4-alpha-glucan branching enzyme (EC 2.4.1.18) (Glycogen branching enzyme) (Brancher enzyme).

LRCH4_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.003109 (rank : 65)
Query Neighborhood Hits	66	Target Neighborhood Hits	305	Shared Neighborhood Hits	3
SwissProt Accessions	O75427, Q8WV85, Q96ID0	Gene names	LRCH4, LRN, LRRN4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4 (Leucine-rich neuronal protein).

SAC3_HUMAN
θ value	6.88961 (rank : 56)	NC score	0.014285 (rank : 47)
Query Neighborhood Hits	66	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q92562, Q53H49, Q5TCS6	Gene names	SAC3, KIAA0274
Domain Architecture
Description	SAC domain-containing protein 3.

UBP36_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.009167 (rank : 56)
Query Neighborhood Hits	66	Target Neighborhood Hits	232	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

ARP10_MOUSE
θ value	8.99809 (rank : 58)	NC score	0.004888 (rank : 62)
Query Neighborhood Hits	66	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZB7, Q99LU1	Gene names	Actr10, Act11, Actr11, Arp11
Domain Architecture
Description	Actin-related protein 10.

CI079_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.016531 (rank : 41)
Query Neighborhood Hits	66	Target Neighborhood Hits	288	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

CMTA2_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.016318 (rank : 42)
Query Neighborhood Hits	66	Target Neighborhood Hits	216	Shared Neighborhood Hits	6
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

DNM1L_MOUSE
θ value	8.99809 (rank : 61)	NC score	0.005135 (rank : 61)
Query Neighborhood Hits	66	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K1M6, Q8BNQ5, Q8BQ64, Q8CGD0, Q8K1A1	Gene names	Dnm1l, Drp1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-related protein 1) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple).

IL4RA_MOUSE
θ value	8.99809 (rank : 62)	NC score	0.012020 (rank : 52)
Query Neighborhood Hits	66	Target Neighborhood Hits	194	Shared Neighborhood Hits	8
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

KCNQ4_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.004041 (rank : 64)
Query Neighborhood Hits	66	Target Neighborhood Hits	136	Shared Neighborhood Hits	3
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

MLL2_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.013675 (rank : 48)
Query Neighborhood Hits	66	Target Neighborhood Hits	1788	Shared Neighborhood Hits	25
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SAC3_MOUSE
θ value	8.99809 (rank : 65)	NC score	0.013329 (rank : 50)
Query Neighborhood Hits	66	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WF7, Q6A092	Gene names	Sac3, Kiaa0274
Domain Architecture	No domain graphic available
Description	SAC domain-containing protein 3.

SYTL2_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.007972 (rank : 57)
Query Neighborhood Hits	66	Target Neighborhood Hits	248	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

CT038_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.149226 (rank : 11)
Query Neighborhood Hits	66	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NUV7, Q5T1U4, Q9H1L1, Q9H1Z0	Gene names	C20orf38
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf38.

Hits sorted by NC score

HEM1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	66	Target Neighborhood Hits	66	Shared Neighborhood Hits	66
SwissProt Accessions	Q8VC19, Q64453	Gene names	Alas1
Domain Architecture	No domain graphic available
Description	5-aminolevulinate synthase, nonspecific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-H).

HEM1_HUMAN
NC score	0.990798 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	66	Target Neighborhood Hits	45	Shared Neighborhood Hits	17
SwissProt Accessions	P13196	Gene names	ALAS1, ALASH
Domain Architecture
Description	5-aminolevulinate synthase, nonspecific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-H).

HEM0_MOUSE
NC score	0.984305 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	66	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	P08680, Q64452, Q9DCN0	Gene names	Alas2
Domain Architecture
Description	5-aminolevulinate synthase, erythroid-specific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta- aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-E).

HEM0_HUMAN
NC score	0.984095 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	66	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	P22557, Q13735	Gene names	ALAS2, ALASE, ASB
Domain Architecture
Description	5-aminolevulinate synthase, erythroid-specific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta- aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-E).

KBL_MOUSE
NC score	0.893235 (rank : 5)	θ value	8.28633e-54 (rank : 5)
Query Neighborhood Hits	66	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	O88986	Gene names	Gcat, Kbl
Domain Architecture
Description	2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial precursor (EC 2.3.1.29) (AKB ligase) (Glycine acetyltransferase).

KBL_HUMAN
NC score	0.889807 (rank : 6)	θ value	2.3352e-48 (rank : 6)
Query Neighborhood Hits	66	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	O75600, Q96CA9	Gene names	GCAT, KBL
Domain Architecture
Description	2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial precursor (EC 2.3.1.29) (AKB ligase) (Glycine acetyltransferase).

LCB2_MOUSE
NC score	0.813930 (rank : 7)	θ value	4.88048e-38 (rank : 7)
Query Neighborhood Hits	66	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	P97363, P97356	Gene names	Sptlc2, Lcb2
Domain Architecture
Description	Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Serine-palmitoyl-CoA transferase 2) (SPT 2).

LCB2_HUMAN
NC score	0.811708 (rank : 8)	θ value	1.20211e-36 (rank : 8)
Query Neighborhood Hits	66	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	O15270, Q16685	Gene names	SPTLC2, KIAA0526, LCB2
Domain Architecture
Description	Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Serine-palmitoyl-CoA transferase 2) (SPT 2).

LCB1_MOUSE
NC score	0.774564 (rank : 9)	θ value	4.01107e-24 (rank : 9)
Query Neighborhood Hits	66	Target Neighborhood Hits	22	Shared Neighborhood Hits	10
SwissProt Accessions	O35704, O54813	Gene names	Sptlc1, Lcb1
Domain Architecture
Description	Serine palmitoyltransferase 1 (EC 2.3.1.50) (Long chain base biosynthesis protein 1) (LCB 1) (Serine-palmitoyl-CoA transferase 1) (SPT 1) (SPT1).

LCB1_HUMAN
NC score	0.772738 (rank : 10)	θ value	8.93572e-24 (rank : 10)
Query Neighborhood Hits	66	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	O15269	Gene names	SPTLC1, LCB1
Domain Architecture
Description	Serine palmitoyltransferase 1 (EC 2.3.1.50) (Long chain base biosynthesis protein 1) (LCB 1) (Serine-palmitoyl-CoA transferase 1) (SPT 1) (SPT1).

CT038_HUMAN
NC score	0.149226 (rank : 11)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	66	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NUV7, Q5T1U4, Q9H1L1, Q9H1Z0	Gene names	C20orf38
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf38.

CCD37_HUMAN
NC score	0.047332 (rank : 12)	θ value	0.0113563 (rank : 11)
Query Neighborhood Hits	66	Target Neighborhood Hits	248	Shared Neighborhood Hits	3
SwissProt Accessions	Q494V2, Q494V1, Q494V4, Q8N838	Gene names	CCDC37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

SRRM2_HUMAN
NC score	0.041236 (rank : 13)	θ value	0.0148317 (rank : 12)
Query Neighborhood Hits	66	Target Neighborhood Hits	1296	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

DAB1_MOUSE
NC score	0.039543 (rank : 14)	θ value	0.21417 (rank : 15)
Query Neighborhood Hits	66	Target Neighborhood Hits	145	Shared Neighborhood Hits	11
SwissProt Accessions	P97318, P97316, P97317	Gene names	Dab1
Domain Architecture
Description	Disabled homolog 1.

ATX2L_HUMAN
NC score	0.035621 (rank : 15)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	66	Target Neighborhood Hits	443	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

ATE1_HUMAN
NC score	0.035472 (rank : 16)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	66	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	O95260, O95261, Q8WW04	Gene names	ATE1
Domain Architecture
Description	Arginyl-tRNA--protein transferase 1 (EC 2.3.2.8) (R-transferase 1) (Arginyltransferase 1) (Arginine-tRNA--protein transferase 1).

NIT1_HUMAN
NC score	0.034959 (rank : 17)	θ value	0.47712 (rank : 16)
Query Neighborhood Hits	66	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q86X76, O76091	Gene names	NIT1
Domain Architecture
Description	Nitrilase homolog 1 (EC 3.5.-.-).

SRRM2_MOUSE
NC score	0.032170 (rank : 18)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	66	Target Neighborhood Hits	1470	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ATX2L_MOUSE
NC score	0.032062 (rank : 19)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	66	Target Neighborhood Hits	401	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

DAB1_HUMAN
NC score	0.030891 (rank : 20)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	66	Target Neighborhood Hits	219	Shared Neighborhood Hits	12
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

RERE_MOUSE
NC score	0.029869 (rank : 21)	θ value	0.62314 (rank : 17)
Query Neighborhood Hits	66	Target Neighborhood Hits	785	Shared Neighborhood Hits	22
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

ATN1_HUMAN
NC score	0.028390 (rank : 22)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	66	Target Neighborhood Hits	676	Shared Neighborhood Hits	18
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

MAP4_MOUSE
NC score	0.027210 (rank : 23)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	66	Target Neighborhood Hits	409	Shared Neighborhood Hits	15
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

CEP57_HUMAN
NC score	0.025604 (rank : 24)	θ value	0.21417 (rank : 14)
Query Neighborhood Hits	66	Target Neighborhood Hits	576	Shared Neighborhood Hits	4
SwissProt Accessions	Q86XR8, Q14704, Q8IXP0, Q9BVF9	Gene names	CEP57, KIAA0092, TSP57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin) (FGF2-interacting protein).

TXND2_HUMAN
NC score	0.024122 (rank : 25)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	66	Target Neighborhood Hits	793	Shared Neighborhood Hits	20
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

WDR46_MOUSE
NC score	0.024018 (rank : 26)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	66	Target Neighborhood Hits	243	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

BAT2_HUMAN
NC score	0.023810 (rank : 27)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	66	Target Neighborhood Hits	931	Shared Neighborhood Hits	25
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

REXO4_HUMAN
NC score	0.023478 (rank : 28)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	66	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9GZR2, Q5T8S4, Q5T8S5, Q5T8S6, Q9GZW3	Gene names	REXO4, PMC2, XPMC2H
Domain Architecture	No domain graphic available
Description	RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (hPMC2) (Prevents mitotic catastrophe 2 protein homolog).

FA13C_HUMAN
NC score	0.023322 (rank : 29)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	66	Target Neighborhood Hits	94	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

INGR1_MOUSE
NC score	0.022422 (rank : 30)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	66	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	P15261	Gene names	Ifngr1, Ifngr
Domain Architecture
Description	Interferon-gamma receptor alpha chain precursor (IFN-gamma-R1) (CD119 antigen).

NCOA6_HUMAN
NC score	0.022257 (rank : 31)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	66	Target Neighborhood Hits	1202	Shared Neighborhood Hits	26
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

MAP4_HUMAN
NC score	0.021774 (rank : 32)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	66	Target Neighborhood Hits	428	Shared Neighborhood Hits	14
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

CBP_HUMAN
NC score	0.021683 (rank : 33)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	66	Target Neighborhood Hits	941	Shared Neighborhood Hits	22
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

PCLO_MOUSE
NC score	0.021428 (rank : 34)	θ value	0.163984 (rank : 13)
Query Neighborhood Hits	66	Target Neighborhood Hits	2275	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RCN1_MOUSE
NC score	0.021036 (rank : 35)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	66	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	Q05186, Q3TVU3	Gene names	Rcn1, Rca1, Rcn
Domain Architecture
Description	Reticulocalbin-1 precursor.

TGON2_HUMAN
NC score	0.019302 (rank : 36)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	66	Target Neighborhood Hits	1037	Shared Neighborhood Hits	23
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

CEP57_MOUSE
NC score	0.018399 (rank : 37)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	66	Target Neighborhood Hits	580	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

RCN1_HUMAN
NC score	0.017983 (rank : 38)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	66	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	Q15293	Gene names	RCN1, RCN
Domain Architecture
Description	Reticulocalbin-1 precursor.

GLGB_HUMAN
NC score	0.017185 (rank : 39)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	66	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q04446, Q96EN0	Gene names	GBE1
Domain Architecture
Description	1,4-alpha-glucan branching enzyme (EC 2.4.1.18) (Glycogen branching enzyme) (Brancher enzyme).

IF35_HUMAN
NC score	0.017075 (rank : 40)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	66	Target Neighborhood Hits	130	Shared Neighborhood Hits	4
SwissProt Accessions	O00303, Q8N978	Gene names	EIF3S5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

CI079_HUMAN
NC score	0.016531 (rank : 41)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	66	Target Neighborhood Hits	288	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

CMTA2_MOUSE
NC score	0.016318 (rank : 42)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	66	Target Neighborhood Hits	216	Shared Neighborhood Hits	6
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

LMBL3_MOUSE
NC score	0.015418 (rank : 43)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	66	Target Neighborhood Hits	212	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BLB7, Q641L7, Q6ZPI2, Q8C0G4	Gene names	L3mbtl3
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein).

3BP2_MOUSE
NC score	0.014905 (rank : 44)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	66	Target Neighborhood Hits	142	Shared Neighborhood Hits	4
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

ENAH_HUMAN
NC score	0.014610 (rank : 45)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	66	Target Neighborhood Hits	784	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

CJ047_MOUSE
NC score	0.014403 (rank : 46)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	66	Target Neighborhood Hits	76	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C5R2, Q8R017, Q8R2Z9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf47 homolog.

SAC3_HUMAN
NC score	0.014285 (rank : 47)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	66	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q92562, Q53H49, Q5TCS6	Gene names	SAC3, KIAA0274
Domain Architecture
Description	SAC domain-containing protein 3.

MLL2_HUMAN
NC score	0.013675 (rank : 48)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	66	Target Neighborhood Hits	1788	Shared Neighborhood Hits	25
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MTMR3_HUMAN
NC score	0.013613 (rank : 49)	θ value	0.813845 (rank : 22)
Query Neighborhood Hits	66	Target Neighborhood Hits	163	Shared Neighborhood Hits	3
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

SAC3_MOUSE
NC score	0.013329 (rank : 50)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	66	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WF7, Q6A092	Gene names	Sac3, Kiaa0274
Domain Architecture	No domain graphic available
Description	SAC domain-containing protein 3.

UBP42_HUMAN
NC score	0.012250 (rank : 51)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	66	Target Neighborhood Hits	445	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

IL4RA_MOUSE
NC score	0.012020 (rank : 52)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	66	Target Neighborhood Hits	194	Shared Neighborhood Hits	8
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

PO6F2_HUMAN
NC score	0.011867 (rank : 53)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	66	Target Neighborhood Hits	618	Shared Neighborhood Hits	15
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

TACC3_HUMAN
NC score	0.010717 (rank : 54)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	66	Target Neighborhood Hits	779	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

HTSF1_HUMAN
NC score	0.010600 (rank : 55)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	66	Target Neighborhood Hits	408	Shared Neighborhood Hits	5
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

UBP36_HUMAN
NC score	0.009167 (rank : 56)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	66	Target Neighborhood Hits	232	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

SYTL2_HUMAN
NC score	0.007972 (rank : 57)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	66	Target Neighborhood Hits	248	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

CCD55_HUMAN
NC score	0.007920 (rank : 58)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	66	Target Neighborhood Hits	513	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

ROBO3_HUMAN
NC score	0.006939 (rank : 59)	θ value	0.813845 (rank : 23)
Query Neighborhood Hits	66	Target Neighborhood Hits	570	Shared Neighborhood Hits	11
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

MYO9B_HUMAN
NC score	0.005653 (rank : 60)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	66	Target Neighborhood Hits	641	Shared Neighborhood Hits	15
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

DNM1L_MOUSE
NC score	0.005135 (rank : 61)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	66	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K1M6, Q8BNQ5, Q8BQ64, Q8CGD0, Q8K1A1	Gene names	Dnm1l, Drp1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-related protein 1) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple).

ARP10_MOUSE
NC score	0.004888 (rank : 62)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	66	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZB7, Q99LU1	Gene names	Actr10, Act11, Actr11, Arp11
Domain Architecture
Description	Actin-related protein 10.

BMP2K_HUMAN
NC score	0.004332 (rank : 63)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	66	Target Neighborhood Hits	867	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NSY1, O94791, Q8IYF2, Q8N2G7, Q8NHG9, Q9NTG8	Gene names	BMP2K, BIKE
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

KCNQ4_HUMAN
NC score	0.004041 (rank : 64)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	66	Target Neighborhood Hits	136	Shared Neighborhood Hits	3
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

LRCH4_HUMAN
NC score	0.003109 (rank : 65)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	66	Target Neighborhood Hits	305	Shared Neighborhood Hits	3
SwissProt Accessions	O75427, Q8WV85, Q96ID0	Gene names	LRCH4, LRN, LRRN4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4 (Leucine-rich neuronal protein).

STK39_MOUSE
NC score	0.000040 (rank : 66)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	66	Target Neighborhood Hits	915	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1W9, Q80W13	Gene names	Stk39, Spak
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39).

EPHB3_MOUSE
NC score	-0.000673 (rank : 67)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	66	Target Neighborhood Hits	996	Shared Neighborhood Hits	5
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).