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Network neighborhood for query Sequence : LCB2_MOUSE

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LCB2_MOUSE
SwissProt Accessions	P97363, P97356	Gene names	Sptlc2, Lcb2
Domain Architecture
Description	Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Serine-palmitoyl-CoA transferase 2) (SPT 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

LCB2_HUMAN
θ value	0 (rank : 1)	NC score	0.999899 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	O15270, Q16685	Gene names	SPTLC2, KIAA0526, LCB2
Domain Architecture
Description	Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Serine-palmitoyl-CoA transferase 2) (SPT 2).

LCB2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	P97363, P97356	Gene names	Sptlc2, Lcb2
Domain Architecture
Description	Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Serine-palmitoyl-CoA transferase 2) (SPT 2).

KBL_MOUSE
θ value	3.72821e-46 (rank : 3)	NC score	0.880526 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	O88986	Gene names	Gcat, Kbl
Domain Architecture
Description	2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial precursor (EC 2.3.1.29) (AKB ligase) (Glycine acetyltransferase).

KBL_HUMAN
θ value	9.50281e-42 (rank : 4)	NC score	0.875050 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	O75600, Q96CA9	Gene names	GCAT, KBL
Domain Architecture
Description	2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial precursor (EC 2.3.1.29) (AKB ligase) (Glycine acetyltransferase).

LCB1_HUMAN
θ value	7.52953e-39 (rank : 5)	NC score	0.850848 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	O15269	Gene names	SPTLC1, LCB1
Domain Architecture
Description	Serine palmitoyltransferase 1 (EC 2.3.1.50) (Long chain base biosynthesis protein 1) (LCB 1) (Serine-palmitoyl-CoA transferase 1) (SPT 1) (SPT1).

HEM0_MOUSE
θ value	1.28434e-38 (rank : 6)	NC score	0.828728 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	P08680, Q64452, Q9DCN0	Gene names	Alas2
Domain Architecture
Description	5-aminolevulinate synthase, erythroid-specific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta- aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-E).

LCB1_MOUSE
θ value	2.19075e-38 (rank : 7)	NC score	0.850211 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	22	Shared Neighborhood Hits	10
SwissProt Accessions	O35704, O54813	Gene names	Sptlc1, Lcb1
Domain Architecture
Description	Serine palmitoyltransferase 1 (EC 2.3.1.50) (Long chain base biosynthesis protein 1) (LCB 1) (Serine-palmitoyl-CoA transferase 1) (SPT 1) (SPT1).

HEM1_MOUSE
θ value	4.88048e-38 (rank : 8)	NC score	0.813930 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	66	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VC19, Q64453	Gene names	Alas1
Domain Architecture	No domain graphic available
Description	5-aminolevulinate synthase, nonspecific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-H).

HEM1_HUMAN
θ value	1.08726e-37 (rank : 9)	NC score	0.818621 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	45	Shared Neighborhood Hits	10
SwissProt Accessions	P13196	Gene names	ALAS1, ALASH
Domain Architecture
Description	5-aminolevulinate synthase, nonspecific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-H).

HEM0_HUMAN
θ value	3.16345e-37 (rank : 10)	NC score	0.826137 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	P22557, Q13735	Gene names	ALAS2, ALASE, ASB
Domain Architecture
Description	5-aminolevulinate synthase, erythroid-specific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta- aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-E).

CT038_HUMAN
θ value	1.99529e-15 (rank : 11)	NC score	0.490523 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NUV7, Q5T1U4, Q9H1L1, Q9H1Z0	Gene names	C20orf38
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf38.

MDN1_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.011447 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	662	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

Hits sorted by NC score

LCB2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	P97363, P97356	Gene names	Sptlc2, Lcb2
Domain Architecture
Description	Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Serine-palmitoyl-CoA transferase 2) (SPT 2).

LCB2_HUMAN
NC score	0.999899 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	O15270, Q16685	Gene names	SPTLC2, KIAA0526, LCB2
Domain Architecture
Description	Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Serine-palmitoyl-CoA transferase 2) (SPT 2).

KBL_MOUSE
NC score	0.880526 (rank : 3)	θ value	3.72821e-46 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	O88986	Gene names	Gcat, Kbl
Domain Architecture
Description	2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial precursor (EC 2.3.1.29) (AKB ligase) (Glycine acetyltransferase).

KBL_HUMAN
NC score	0.875050 (rank : 4)	θ value	9.50281e-42 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	O75600, Q96CA9	Gene names	GCAT, KBL
Domain Architecture
Description	2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial precursor (EC 2.3.1.29) (AKB ligase) (Glycine acetyltransferase).

LCB1_HUMAN
NC score	0.850848 (rank : 5)	θ value	7.52953e-39 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	O15269	Gene names	SPTLC1, LCB1
Domain Architecture
Description	Serine palmitoyltransferase 1 (EC 2.3.1.50) (Long chain base biosynthesis protein 1) (LCB 1) (Serine-palmitoyl-CoA transferase 1) (SPT 1) (SPT1).

LCB1_MOUSE
NC score	0.850211 (rank : 6)	θ value	2.19075e-38 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	22	Shared Neighborhood Hits	10
SwissProt Accessions	O35704, O54813	Gene names	Sptlc1, Lcb1
Domain Architecture
Description	Serine palmitoyltransferase 1 (EC 2.3.1.50) (Long chain base biosynthesis protein 1) (LCB 1) (Serine-palmitoyl-CoA transferase 1) (SPT 1) (SPT1).

HEM0_MOUSE
NC score	0.828728 (rank : 7)	θ value	1.28434e-38 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	P08680, Q64452, Q9DCN0	Gene names	Alas2
Domain Architecture
Description	5-aminolevulinate synthase, erythroid-specific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta- aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-E).

HEM0_HUMAN
NC score	0.826137 (rank : 8)	θ value	3.16345e-37 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	P22557, Q13735	Gene names	ALAS2, ALASE, ASB
Domain Architecture
Description	5-aminolevulinate synthase, erythroid-specific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta- aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-E).

HEM1_HUMAN
NC score	0.818621 (rank : 9)	θ value	1.08726e-37 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	45	Shared Neighborhood Hits	10
SwissProt Accessions	P13196	Gene names	ALAS1, ALASH
Domain Architecture
Description	5-aminolevulinate synthase, nonspecific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-H).

HEM1_MOUSE
NC score	0.813930 (rank : 10)	θ value	4.88048e-38 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	66	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VC19, Q64453	Gene names	Alas1
Domain Architecture	No domain graphic available
Description	5-aminolevulinate synthase, nonspecific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-H).

CT038_HUMAN
NC score	0.490523 (rank : 11)	θ value	1.99529e-15 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NUV7, Q5T1U4, Q9H1L1, Q9H1Z0	Gene names	C20orf38
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf38.

MDN1_HUMAN
NC score	0.011447 (rank : 12)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	662	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).