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Network neighborhood for query Sequence : FA13C_HUMAN

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FA13C_HUMAN
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FA13C_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	94	Target Neighborhood Hits	94	Shared Neighborhood Hits	94
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

FA13C_MOUSE
θ value	0 (rank : 2)	NC score	0.964783 (rank : 2)
Query Neighborhood Hits	94	Target Neighborhood Hits	79	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

FA13A_HUMAN
θ value	3.59435e-57 (rank : 3)	NC score	0.840726 (rank : 4)
Query Neighborhood Hits	94	Target Neighborhood Hits	102	Shared Neighborhood Hits	10
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

FA13A_MOUSE
θ value	3.974e-56 (rank : 4)	NC score	0.843498 (rank : 3)
Query Neighborhood Hits	94	Target Neighborhood Hits	83	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

CE005_MOUSE
θ value	5.02714e-51 (rank : 5)	NC score	0.620106 (rank : 5)
Query Neighborhood Hits	94	Target Neighborhood Hits	238	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

CE005_HUMAN
θ value	1.28137e-46 (rank : 6)	NC score	0.616766 (rank : 6)
Query Neighborhood Hits	94	Target Neighborhood Hits	213	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

RAI14_MOUSE
θ value	0.000461057 (rank : 7)	NC score	0.030157 (rank : 54)
Query Neighborhood Hits	94	Target Neighborhood Hits	1505	Shared Neighborhood Hits	34
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

NRBF2_MOUSE
θ value	0.0193708 (rank : 8)	NC score	0.072518 (rank : 7)
Query Neighborhood Hits	94	Target Neighborhood Hits	113	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VCQ3, Q9DCG3	Gene names	Nrbf2
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding factor 2 (NRBF-2).

PRG4_MOUSE
θ value	0.0252991 (rank : 9)	NC score	0.055200 (rank : 22)
Query Neighborhood Hits	94	Target Neighborhood Hits	624	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

CN037_MOUSE
θ value	0.0563607 (rank : 10)	NC score	0.066184 (rank : 11)
Query Neighborhood Hits	94	Target Neighborhood Hits	179	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

NACAM_MOUSE
θ value	0.0736092 (rank : 11)	NC score	0.049062 (rank : 35)
Query Neighborhood Hits	94	Target Neighborhood Hits	1866	Shared Neighborhood Hits	48
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SYAP1_MOUSE
θ value	0.0736092 (rank : 12)	NC score	0.064712 (rank : 12)
Query Neighborhood Hits	94	Target Neighborhood Hits	55	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D5V6, Q3UI67, Q9D870	Gene names	Syap1
Domain Architecture
Description	Synapse-associated protein 1.

TEX14_MOUSE
θ value	0.0961366 (rank : 13)	NC score	0.027220 (rank : 60)
Query Neighborhood Hits	94	Target Neighborhood Hits	1333	Shared Neighborhood Hits	20
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

CCD16_HUMAN
θ value	0.125558 (rank : 14)	NC score	0.051831 (rank : 29)
Query Neighborhood Hits	94	Target Neighborhood Hits	190	Shared Neighborhood Hits	6
SwissProt Accessions	Q96NB3, Q96F60, Q96GZ5, Q9BU38	Gene names	CCDC16
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 16.

CCNE1_MOUSE
θ value	0.125558 (rank : 15)	NC score	0.034491 (rank : 47)
Query Neighborhood Hits	94	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q61457	Gene names	Ccne1, Ccne
Domain Architecture
Description	G1/S-specific cyclin-E1.

RTP3_MOUSE
θ value	0.163984 (rank : 16)	NC score	0.053763 (rank : 23)
Query Neighborhood Hits	94	Target Neighborhood Hits	374	Shared Neighborhood Hits	20
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

AFF1_HUMAN
θ value	0.21417 (rank : 17)	NC score	0.046656 (rank : 40)
Query Neighborhood Hits	94	Target Neighborhood Hits	506	Shared Neighborhood Hits	24
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

TCOF_HUMAN
θ value	0.21417 (rank : 18)	NC score	0.049687 (rank : 34)
Query Neighborhood Hits	94	Target Neighborhood Hits	543	Shared Neighborhood Hits	18
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TTBK1_HUMAN
θ value	0.21417 (rank : 19)	NC score	0.021444 (rank : 73)
Query Neighborhood Hits	94	Target Neighborhood Hits	1058	Shared Neighborhood Hits	24
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

DSPP_HUMAN
θ value	0.279714 (rank : 20)	NC score	0.048583 (rank : 36)
Query Neighborhood Hits	94	Target Neighborhood Hits	645	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

CO027_HUMAN
θ value	0.365318 (rank : 21)	NC score	0.051303 (rank : 31)
Query Neighborhood Hits	94	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q2M3C6, Q8N993, Q96LL5	Gene names	C15orf27
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf27.

DMP1_HUMAN
θ value	0.365318 (rank : 22)	NC score	0.055377 (rank : 21)
Query Neighborhood Hits	94	Target Neighborhood Hits	491	Shared Neighborhood Hits	19
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

M4K4_MOUSE
θ value	0.365318 (rank : 23)	NC score	0.014379 (rank : 87)
Query Neighborhood Hits	94	Target Neighborhood Hits	1560	Shared Neighborhood Hits	28
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

PAK1_HUMAN
θ value	0.365318 (rank : 24)	NC score	0.011437 (rank : 99)
Query Neighborhood Hits	94	Target Neighborhood Hits	873	Shared Neighborhood Hits	13
SwissProt Accessions	Q13153, O75561, Q13567, Q32M53, Q32M54, Q86W79	Gene names	PAK1
Domain Architecture
Description	Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK).

CN155_HUMAN
θ value	0.47712 (rank : 25)	NC score	0.047768 (rank : 37)
Query Neighborhood Hits	94	Target Neighborhood Hits	385	Shared Neighborhood Hits	20
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

EP15R_MOUSE
θ value	0.47712 (rank : 26)	NC score	0.032855 (rank : 51)
Query Neighborhood Hits	94	Target Neighborhood Hits	1135	Shared Neighborhood Hits	30
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

M4K4_HUMAN
θ value	0.47712 (rank : 27)	NC score	0.014054 (rank : 89)
Query Neighborhood Hits	94	Target Neighborhood Hits	1589	Shared Neighborhood Hits	28
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

PAK1_MOUSE
θ value	0.47712 (rank : 28)	NC score	0.011356 (rank : 100)
Query Neighborhood Hits	94	Target Neighborhood Hits	878	Shared Neighborhood Hits	14
SwissProt Accessions	O88643	Gene names	Pak1, Paka
Domain Architecture
Description	Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) (CDC42/RAC effector kinase PAK-A).

TMM25_HUMAN
θ value	0.47712 (rank : 29)	NC score	0.044434 (rank : 41)
Query Neighborhood Hits	94	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q86YD3, Q6UW89, Q86UA7, Q96KA6, Q96MW9	Gene names	TMEM25
Domain Architecture	No domain graphic available
Description	Transmembrane protein 25 precursor.

APC_HUMAN
θ value	0.62314 (rank : 30)	NC score	0.036815 (rank : 46)
Query Neighborhood Hits	94	Target Neighborhood Hits	603	Shared Neighborhood Hits	26
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

BAZ2B_HUMAN
θ value	0.62314 (rank : 31)	NC score	0.026757 (rank : 62)
Query Neighborhood Hits	94	Target Neighborhood Hits	803	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

IFT74_HUMAN
θ value	0.62314 (rank : 32)	NC score	0.027123 (rank : 61)
Query Neighborhood Hits	94	Target Neighborhood Hits	949	Shared Neighborhood Hits	21
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

KINH_HUMAN
θ value	0.62314 (rank : 33)	NC score	0.017871 (rank : 78)
Query Neighborhood Hits	94	Target Neighborhood Hits	1231	Shared Neighborhood Hits	27
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

HEM1_MOUSE
θ value	0.813845 (rank : 34)	NC score	0.023322 (rank : 70)
Query Neighborhood Hits	94	Target Neighborhood Hits	66	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VC19, Q64453	Gene names	Alas1
Domain Architecture	No domain graphic available
Description	5-aminolevulinate synthase, nonspecific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-H).

PRGR_HUMAN
θ value	0.813845 (rank : 35)	NC score	0.012952 (rank : 95)
Query Neighborhood Hits	94	Target Neighborhood Hits	163	Shared Neighborhood Hits	5
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

TRI25_HUMAN
θ value	0.813845 (rank : 36)	NC score	0.015471 (rank : 84)
Query Neighborhood Hits	94	Target Neighborhood Hits	472	Shared Neighborhood Hits	7
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

DSPP_MOUSE
θ value	1.06291 (rank : 37)	NC score	0.041212 (rank : 42)
Query Neighborhood Hits	94	Target Neighborhood Hits	491	Shared Neighborhood Hits	17
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

NCOR2_MOUSE
θ value	1.06291 (rank : 38)	NC score	0.047302 (rank : 38)
Query Neighborhood Hits	94	Target Neighborhood Hits	790	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

E41L2_HUMAN
θ value	1.38821 (rank : 39)	NC score	0.012603 (rank : 97)
Query Neighborhood Hits	94	Target Neighborhood Hits	287	Shared Neighborhood Hits	12
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

MAP1B_MOUSE
θ value	1.38821 (rank : 40)	NC score	0.046976 (rank : 39)
Query Neighborhood Hits	94	Target Neighborhood Hits	977	Shared Neighborhood Hits	36
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MYBB_HUMAN
θ value	1.38821 (rank : 41)	NC score	0.029268 (rank : 56)
Query Neighborhood Hits	94	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	P10244	Gene names	MYBL2, BMYB
Domain Architecture
Description	Myb-related protein B (B-Myb).

NCOR1_MOUSE
θ value	1.38821 (rank : 42)	NC score	0.033076 (rank : 50)
Query Neighborhood Hits	94	Target Neighborhood Hits	521	Shared Neighborhood Hits	20
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

OGFR_HUMAN
θ value	1.38821 (rank : 43)	NC score	0.029370 (rank : 55)
Query Neighborhood Hits	94	Target Neighborhood Hits	1582	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

K1949_MOUSE
θ value	1.81305 (rank : 44)	NC score	0.030571 (rank : 53)
Query Neighborhood Hits	94	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BQ30, Q3UDS6, Q8CEY9, Q8R3D8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1949 homolog.

MLL3_MOUSE
θ value	1.81305 (rank : 45)	NC score	0.021863 (rank : 72)
Query Neighborhood Hits	94	Target Neighborhood Hits	1399	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

CELR2_HUMAN
θ value	2.36792 (rank : 46)	NC score	0.005946 (rank : 110)
Query Neighborhood Hits	94	Target Neighborhood Hits	657	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

FANCE_HUMAN
θ value	2.36792 (rank : 47)	NC score	0.036991 (rank : 45)
Query Neighborhood Hits	94	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HB96, Q4ZGH2	Gene names	FANCE
Domain Architecture	No domain graphic available
Description	Fanconi anemia group E protein (Protein FACE).

IF39_HUMAN
θ value	2.36792 (rank : 48)	NC score	0.039757 (rank : 44)
Query Neighborhood Hits	94	Target Neighborhood Hits	187	Shared Neighborhood Hits	11
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

JHD1B_HUMAN
θ value	2.36792 (rank : 49)	NC score	0.014238 (rank : 88)
Query Neighborhood Hits	94	Target Neighborhood Hits	178	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

MAML3_HUMAN
θ value	2.36792 (rank : 50)	NC score	0.026639 (rank : 63)
Query Neighborhood Hits	94	Target Neighborhood Hits	323	Shared Neighborhood Hits	17
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

MDM2_HUMAN
θ value	2.36792 (rank : 51)	NC score	0.024060 (rank : 66)
Query Neighborhood Hits	94	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	Q00987, Q13226, Q13297, Q13298, Q13299, Q13300, Q13301, Q53XW0, Q71TW9, Q9UGI3, Q9UMT8	Gene names	MDM2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2).

MRCKB_HUMAN
θ value	2.36792 (rank : 52)	NC score	0.009649 (rank : 102)
Query Neighborhood Hits	94	Target Neighborhood Hits	2239	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

CDYL_MOUSE
θ value	3.0926 (rank : 53)	NC score	0.013054 (rank : 94)
Query Neighborhood Hits	94	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WTK2	Gene names	Cdyl
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

CELR2_MOUSE
θ value	3.0926 (rank : 54)	NC score	0.006087 (rank : 109)
Query Neighborhood Hits	94	Target Neighborhood Hits	584	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

CP053_HUMAN
θ value	3.0926 (rank : 55)	NC score	0.040949 (rank : 43)
Query Neighborhood Hits	94	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BTK6	Gene names	C16orf53
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf53.

DIDO1_HUMAN
θ value	3.0926 (rank : 56)	NC score	0.033744 (rank : 49)
Query Neighborhood Hits	94	Target Neighborhood Hits	960	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

RP1L1_HUMAN
θ value	3.0926 (rank : 57)	NC score	0.023415 (rank : 69)
Query Neighborhood Hits	94	Target Neighborhood Hits	1072	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

TITIN_HUMAN
θ value	3.0926 (rank : 58)	NC score	0.013227 (rank : 92)
Query Neighborhood Hits	94	Target Neighborhood Hits	2923	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ZO1_HUMAN
θ value	3.0926 (rank : 59)	NC score	0.016831 (rank : 80)
Query Neighborhood Hits	94	Target Neighborhood Hits	474	Shared Neighborhood Hits	18
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

BASP_MOUSE
θ value	4.03905 (rank : 60)	NC score	0.034304 (rank : 48)
Query Neighborhood Hits	94	Target Neighborhood Hits	260	Shared Neighborhood Hits	16
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

DNL1_MOUSE
θ value	4.03905 (rank : 61)	NC score	0.021164 (rank : 74)
Query Neighborhood Hits	94	Target Neighborhood Hits	110	Shared Neighborhood Hits	11
SwissProt Accessions	P37913	Gene names	Lig1, Lig-1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

RSPO4_HUMAN
θ value	4.03905 (rank : 62)	NC score	0.013347 (rank : 91)
Query Neighborhood Hits	94	Target Neighborhood Hits	110	Shared Neighborhood Hits	2
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

SMRC2_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.019824 (rank : 77)
Query Neighborhood Hits	94	Target Neighborhood Hits	499	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

TXND2_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.058330 (rank : 18)
Query Neighborhood Hits	94	Target Neighborhood Hits	793	Shared Neighborhood Hits	45
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

AAK1_MOUSE
θ value	5.27518 (rank : 65)	NC score	0.009647 (rank : 103)
Query Neighborhood Hits	94	Target Neighborhood Hits	1051	Shared Neighborhood Hits	23
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

CCD21_HUMAN
θ value	5.27518 (rank : 66)	NC score	0.015079 (rank : 86)
Query Neighborhood Hits	94	Target Neighborhood Hits	1228	Shared Neighborhood Hits	32
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

ESCO2_HUMAN
θ value	5.27518 (rank : 67)	NC score	0.015429 (rank : 85)
Query Neighborhood Hits	94	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q56NI9	Gene names	ESCO2
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO2 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 2) (ECO1 homolog 2).

MILK1_MOUSE
θ value	5.27518 (rank : 68)	NC score	0.016476 (rank : 81)
Query Neighborhood Hits	94	Target Neighborhood Hits	788	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

PACE1_MOUSE
θ value	5.27518 (rank : 69)	NC score	0.015658 (rank : 83)
Query Neighborhood Hits	94	Target Neighborhood Hits	92	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DBQ7, Q6NY01, Q8BQC9, Q8BRJ1	Gene names	Scyl3, Pace1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

PCLO_MOUSE
θ value	5.27518 (rank : 70)	NC score	0.027296 (rank : 59)
Query Neighborhood Hits	94	Target Neighborhood Hits	2275	Shared Neighborhood Hits	61
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PELP1_HUMAN
θ value	5.27518 (rank : 71)	NC score	0.024425 (rank : 65)
Query Neighborhood Hits	94	Target Neighborhood Hits	596	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

SOX30_HUMAN
θ value	5.27518 (rank : 72)	NC score	0.011281 (rank : 101)
Query Neighborhood Hits	94	Target Neighborhood Hits	305	Shared Neighborhood Hits	11
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

TLE3_HUMAN
θ value	5.27518 (rank : 73)	NC score	0.008970 (rank : 105)
Query Neighborhood Hits	94	Target Neighborhood Hits	385	Shared Neighborhood Hits	10
SwissProt Accessions	Q04726, Q8IVV6, Q8WVR2, Q9HCM5	Gene names	TLE3, KIAA1547
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG3).

XYLT1_HUMAN
θ value	5.27518 (rank : 74)	NC score	0.012880 (rank : 96)
Query Neighborhood Hits	94	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q86Y38, Q9H1B6	Gene names	XYLT1, XT1
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 1 (EC 2.4.2.26) (Xylosyltransferase I) (XylT-I) (XT-I) (Peptide O-xylosyltransferase 1).

A2BP1_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.008354 (rank : 106)
Query Neighborhood Hits	94	Target Neighborhood Hits	229	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NWB1, Q9NS20	Gene names	A2BP1, A2BP
Domain Architecture
Description	Ataxin-2-binding protein 1.

BAT2_MOUSE
θ value	6.88961 (rank : 76)	NC score	0.027320 (rank : 58)
Query Neighborhood Hits	94	Target Neighborhood Hits	947	Shared Neighborhood Hits	29
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

ERBB2_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.004665 (rank : 111)
Query Neighborhood Hits	94	Target Neighborhood Hits	1073	Shared Neighborhood Hits	16
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

MAP2_HUMAN
θ value	6.88961 (rank : 78)	NC score	0.023873 (rank : 67)
Query Neighborhood Hits	94	Target Neighborhood Hits	348	Shared Neighborhood Hits	21
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

MAP4_MOUSE
θ value	6.88961 (rank : 79)	NC score	0.030972 (rank : 52)
Query Neighborhood Hits	94	Target Neighborhood Hits	409	Shared Neighborhood Hits	28
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MPP10_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.020732 (rank : 75)
Query Neighborhood Hits	94	Target Neighborhood Hits	306	Shared Neighborhood Hits	14
SwissProt Accessions	O00566	Gene names	MPHOSPH10, MPP10
Domain Architecture
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

NU214_HUMAN
θ value	6.88961 (rank : 81)	NC score	0.024708 (rank : 64)
Query Neighborhood Hits	94	Target Neighborhood Hits	657	Shared Neighborhood Hits	23
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

SAPS1_MOUSE
θ value	6.88961 (rank : 82)	NC score	0.012126 (rank : 98)
Query Neighborhood Hits	94	Target Neighborhood Hits	144	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TSI3, Q80TJ4	Gene names	Saps1, Kiaa1115
Domain Architecture	No domain graphic available
Description	SAPS domain family member 1.

ZO1_MOUSE
θ value	6.88961 (rank : 83)	NC score	0.013611 (rank : 90)
Query Neighborhood Hits	94	Target Neighborhood Hits	453	Shared Neighborhood Hits	11
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ARI5B_HUMAN
θ value	8.99809 (rank : 84)	NC score	0.017678 (rank : 79)
Query Neighborhood Hits	94	Target Neighborhood Hits	328	Shared Neighborhood Hits	22
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

CJ092_HUMAN
θ value	8.99809 (rank : 85)	NC score	0.016206 (rank : 82)
Query Neighborhood Hits	94	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IYW2, Q5JSF7, Q9NTQ5	Gene names	C10orf92
Domain Architecture	No domain graphic available
Description	Protein C10orf92.

FGD5_HUMAN
θ value	8.99809 (rank : 86)	NC score	0.006918 (rank : 108)
Query Neighborhood Hits	94	Target Neighborhood Hits	235	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

MARCS_MOUSE
θ value	8.99809 (rank : 87)	NC score	0.020731 (rank : 76)
Query Neighborhood Hits	94	Target Neighborhood Hits	227	Shared Neighborhood Hits	11
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MYST3_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.023440 (rank : 68)
Query Neighborhood Hits	94	Target Neighborhood Hits	772	Shared Neighborhood Hits	33
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NFH_MOUSE
θ value	8.99809 (rank : 89)	NC score	0.022095 (rank : 71)
Query Neighborhood Hits	94	Target Neighborhood Hits	2247	Shared Neighborhood Hits	55
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

OPTN_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.028671 (rank : 57)
Query Neighborhood Hits	94	Target Neighborhood Hits	827	Shared Neighborhood Hits	22
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

PCDGK_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.003135 (rank : 112)
Query Neighborhood Hits	94	Target Neighborhood Hits	162	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UN70, O60622, Q08192, Q9Y5C4	Gene names	PCDHGC3, PCDH2
Domain Architecture
Description	Protocadherin gamma C3 precursor (PCDH-gamma-C3) (Protocadherin 43) (PC-43) (Protocadherin 2).

TLE3_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.007624 (rank : 107)
Query Neighborhood Hits	94	Target Neighborhood Hits	378	Shared Neighborhood Hits	7
SwissProt Accessions	Q08122, Q923A4	Gene names	Tle3, Esg
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG) (Grg-3).

UTRO_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.009267 (rank : 104)
Query Neighborhood Hits	94	Target Neighborhood Hits	960	Shared Neighborhood Hits	19
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

ZAN_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.013191 (rank : 93)
Query Neighborhood Hits	94	Target Neighborhood Hits	679	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

GMIP_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.059093 (rank : 15)
Query Neighborhood Hits	94	Target Neighborhood Hits	225	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GMIP_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.060249 (rank : 14)
Query Neighborhood Hits	94	Target Neighborhood Hits	202	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GRLF1_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.051460 (rank : 30)
Query Neighborhood Hits	94	Target Neighborhood Hits	167	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

K1688_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.050572 (rank : 33)
Query Neighborhood Hits	94	Target Neighborhood Hits	217	Shared Neighborhood Hits	5
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

K1688_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.052198 (rank : 27)
Query Neighborhood Hits	94	Target Neighborhood Hits	188	Shared Neighborhood Hits	4
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

RGAP1_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.058259 (rank : 19)
Query Neighborhood Hits	94	Target Neighborhood Hits	189	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG01_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.070301 (rank : 8)
Query Neighborhood Hits	94	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

RHG05_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.053137 (rank : 26)
Query Neighborhood Hits	94	Target Neighborhood Hits	158	Shared Neighborhood Hits	2
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG05_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.053202 (rank : 25)
Query Neighborhood Hits	94	Target Neighborhood Hits	165	Shared Neighborhood Hits	3
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG06_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.058898 (rank : 16)
Query Neighborhood Hits	94	Target Neighborhood Hits	114	Shared Neighborhood Hits	3
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG06_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.058358 (rank : 17)
Query Neighborhood Hits	94	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG08_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.053274 (rank : 24)
Query Neighborhood Hits	94	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG08_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.055869 (rank : 20)
Query Neighborhood Hits	94	Target Neighborhood Hits	73	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG18_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.051033 (rank : 32)
Query Neighborhood Hits	94	Target Neighborhood Hits	90	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

RHG18_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.061349 (rank : 13)
Query Neighborhood Hits	94	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG25_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.067597 (rank : 10)
Query Neighborhood Hits	94	Target Neighborhood Hits	550	Shared Neighborhood Hits	13
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.067914 (rank : 9)
Query Neighborhood Hits	94	Target Neighborhood Hits	492	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

TCGAP_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.052154 (rank : 28)
Query Neighborhood Hits	94	Target Neighborhood Hits	409	Shared Neighborhood Hits	13
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

Hits sorted by NC score

FA13C_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	94	Target Neighborhood Hits	94	Shared Neighborhood Hits	94
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

FA13C_MOUSE
NC score	0.964783 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	94	Target Neighborhood Hits	79	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

FA13A_MOUSE
NC score	0.843498 (rank : 3)	θ value	3.974e-56 (rank : 4)
Query Neighborhood Hits	94	Target Neighborhood Hits	83	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

FA13A_HUMAN
NC score	0.840726 (rank : 4)	θ value	3.59435e-57 (rank : 3)
Query Neighborhood Hits	94	Target Neighborhood Hits	102	Shared Neighborhood Hits	10
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

CE005_MOUSE
NC score	0.620106 (rank : 5)	θ value	5.02714e-51 (rank : 5)
Query Neighborhood Hits	94	Target Neighborhood Hits	238	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

CE005_HUMAN
NC score	0.616766 (rank : 6)	θ value	1.28137e-46 (rank : 6)
Query Neighborhood Hits	94	Target Neighborhood Hits	213	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

NRBF2_MOUSE
NC score	0.072518 (rank : 7)	θ value	0.0193708 (rank : 8)
Query Neighborhood Hits	94	Target Neighborhood Hits	113	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VCQ3, Q9DCG3	Gene names	Nrbf2
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding factor 2 (NRBF-2).

RHG01_HUMAN
NC score	0.070301 (rank : 8)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	94	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

RHG25_MOUSE
NC score	0.067914 (rank : 9)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	94	Target Neighborhood Hits	492	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_HUMAN
NC score	0.067597 (rank : 10)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	94	Target Neighborhood Hits	550	Shared Neighborhood Hits	13
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CN037_MOUSE
NC score	0.066184 (rank : 11)	θ value	0.0563607 (rank : 10)
Query Neighborhood Hits	94	Target Neighborhood Hits	179	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

SYAP1_MOUSE
NC score	0.064712 (rank : 12)	θ value	0.0736092 (rank : 12)
Query Neighborhood Hits	94	Target Neighborhood Hits	55	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D5V6, Q3UI67, Q9D870	Gene names	Syap1
Domain Architecture
Description	Synapse-associated protein 1.

RHG18_MOUSE
NC score	0.061349 (rank : 13)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	94	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

GMIP_MOUSE
NC score	0.060249 (rank : 14)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	94	Target Neighborhood Hits	202	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GMIP_HUMAN
NC score	0.059093 (rank : 15)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	94	Target Neighborhood Hits	225	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RHG06_HUMAN
NC score	0.058898 (rank : 16)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	94	Target Neighborhood Hits	114	Shared Neighborhood Hits	3
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG06_MOUSE
NC score	0.058358 (rank : 17)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	94	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

TXND2_HUMAN
NC score	0.058330 (rank : 18)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	94	Target Neighborhood Hits	793	Shared Neighborhood Hits	45
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

RGAP1_HUMAN
NC score	0.058259 (rank : 19)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	94	Target Neighborhood Hits	189	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG08_MOUSE
NC score	0.055869 (rank : 20)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	94	Target Neighborhood Hits	73	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

DMP1_HUMAN
NC score	0.055377 (rank : 21)	θ value	0.365318 (rank : 22)
Query Neighborhood Hits	94	Target Neighborhood Hits	491	Shared Neighborhood Hits	19
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

PRG4_MOUSE
NC score	0.055200 (rank : 22)	θ value	0.0252991 (rank : 9)
Query Neighborhood Hits	94	Target Neighborhood Hits	624	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RTP3_MOUSE
NC score	0.053763 (rank : 23)	θ value	0.163984 (rank : 16)
Query Neighborhood Hits	94	Target Neighborhood Hits	374	Shared Neighborhood Hits	20
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

RHG08_HUMAN
NC score	0.053274 (rank : 24)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	94	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG05_MOUSE
NC score	0.053202 (rank : 25)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	94	Target Neighborhood Hits	165	Shared Neighborhood Hits	3
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG05_HUMAN
NC score	0.053137 (rank : 26)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	94	Target Neighborhood Hits	158	Shared Neighborhood Hits	2
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

K1688_MOUSE
NC score	0.052198 (rank : 27)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	94	Target Neighborhood Hits	188	Shared Neighborhood Hits	4
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

TCGAP_MOUSE
NC score	0.052154 (rank : 28)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	94	Target Neighborhood Hits	409	Shared Neighborhood Hits	13
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CCD16_HUMAN
NC score	0.051831 (rank : 29)	θ value	0.125558 (rank : 14)
Query Neighborhood Hits	94	Target Neighborhood Hits	190	Shared Neighborhood Hits	6
SwissProt Accessions	Q96NB3, Q96F60, Q96GZ5, Q9BU38	Gene names	CCDC16
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 16.

GRLF1_HUMAN
NC score	0.051460 (rank : 30)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	94	Target Neighborhood Hits	167	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

CO027_HUMAN
NC score	0.051303 (rank : 31)	θ value	0.365318 (rank : 21)
Query Neighborhood Hits	94	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q2M3C6, Q8N993, Q96LL5	Gene names	C15orf27
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf27.

RHG18_HUMAN
NC score	0.051033 (rank : 32)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	94	Target Neighborhood Hits	90	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

K1688_HUMAN
NC score	0.050572 (rank : 33)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	94	Target Neighborhood Hits	217	Shared Neighborhood Hits	5
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

TCOF_HUMAN
NC score	0.049687 (rank : 34)	θ value	0.21417 (rank : 18)
Query Neighborhood Hits	94	Target Neighborhood Hits	543	Shared Neighborhood Hits	18
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

NACAM_MOUSE
NC score	0.049062 (rank : 35)	θ value	0.0736092 (rank : 11)
Query Neighborhood Hits	94	Target Neighborhood Hits	1866	Shared Neighborhood Hits	48
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

DSPP_HUMAN
NC score	0.048583 (rank : 36)	θ value	0.279714 (rank : 20)
Query Neighborhood Hits	94	Target Neighborhood Hits	645	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

CN155_HUMAN
NC score	0.047768 (rank : 37)	θ value	0.47712 (rank : 25)
Query Neighborhood Hits	94	Target Neighborhood Hits	385	Shared Neighborhood Hits	20
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

NCOR2_MOUSE
NC score	0.047302 (rank : 38)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	94	Target Neighborhood Hits	790	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

MAP1B_MOUSE
NC score	0.046976 (rank : 39)	θ value	1.38821 (rank : 40)
Query Neighborhood Hits	94	Target Neighborhood Hits	977	Shared Neighborhood Hits	36
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

AFF1_HUMAN
NC score	0.046656 (rank : 40)	θ value	0.21417 (rank : 17)
Query Neighborhood Hits	94	Target Neighborhood Hits	506	Shared Neighborhood Hits	24
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

TMM25_HUMAN
NC score	0.044434 (rank : 41)	θ value	0.47712 (rank : 29)
Query Neighborhood Hits	94	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q86YD3, Q6UW89, Q86UA7, Q96KA6, Q96MW9	Gene names	TMEM25
Domain Architecture	No domain graphic available
Description	Transmembrane protein 25 precursor.

DSPP_MOUSE
NC score	0.041212 (rank : 42)	θ value	1.06291 (rank : 37)
Query Neighborhood Hits	94	Target Neighborhood Hits	491	Shared Neighborhood Hits	17
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

CP053_HUMAN
NC score	0.040949 (rank : 43)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	94	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BTK6	Gene names	C16orf53
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf53.

IF39_HUMAN
NC score	0.039757 (rank : 44)	θ value	2.36792 (rank : 48)
Query Neighborhood Hits	94	Target Neighborhood Hits	187	Shared Neighborhood Hits	11
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

FANCE_HUMAN
NC score	0.036991 (rank : 45)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	94	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HB96, Q4ZGH2	Gene names	FANCE
Domain Architecture	No domain graphic available
Description	Fanconi anemia group E protein (Protein FACE).

APC_HUMAN
NC score	0.036815 (rank : 46)	θ value	0.62314 (rank : 30)
Query Neighborhood Hits	94	Target Neighborhood Hits	603	Shared Neighborhood Hits	26
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

CCNE1_MOUSE
NC score	0.034491 (rank : 47)	θ value	0.125558 (rank : 15)
Query Neighborhood Hits	94	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q61457	Gene names	Ccne1, Ccne
Domain Architecture
Description	G1/S-specific cyclin-E1.

BASP_MOUSE
NC score	0.034304 (rank : 48)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	94	Target Neighborhood Hits	260	Shared Neighborhood Hits	16
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

DIDO1_HUMAN
NC score	0.033744 (rank : 49)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	94	Target Neighborhood Hits	960	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

NCOR1_MOUSE
NC score	0.033076 (rank : 50)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	94	Target Neighborhood Hits	521	Shared Neighborhood Hits	20
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

EP15R_MOUSE
NC score	0.032855 (rank : 51)	θ value	0.47712 (rank : 26)
Query Neighborhood Hits	94	Target Neighborhood Hits	1135	Shared Neighborhood Hits	30
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

MAP4_MOUSE
NC score	0.030972 (rank : 52)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	94	Target Neighborhood Hits	409	Shared Neighborhood Hits	28
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

K1949_MOUSE
NC score	0.030571 (rank : 53)	θ value	1.81305 (rank : 44)
Query Neighborhood Hits	94	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BQ30, Q3UDS6, Q8CEY9, Q8R3D8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1949 homolog.

RAI14_MOUSE
NC score	0.030157 (rank : 54)	θ value	0.000461057 (rank : 7)
Query Neighborhood Hits	94	Target Neighborhood Hits	1505	Shared Neighborhood Hits	34
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

OGFR_HUMAN
NC score	0.029370 (rank : 55)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	94	Target Neighborhood Hits	1582	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

MYBB_HUMAN
NC score	0.029268 (rank : 56)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	94	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	P10244	Gene names	MYBL2, BMYB
Domain Architecture
Description	Myb-related protein B (B-Myb).

OPTN_HUMAN
NC score	0.028671 (rank : 57)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	94	Target Neighborhood Hits	827	Shared Neighborhood Hits	22
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

BAT2_MOUSE
NC score	0.027320 (rank : 58)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	94	Target Neighborhood Hits	947	Shared Neighborhood Hits	29
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

PCLO_MOUSE
NC score	0.027296 (rank : 59)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	94	Target Neighborhood Hits	2275	Shared Neighborhood Hits	61
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

TEX14_MOUSE
NC score	0.027220 (rank : 60)	θ value	0.0961366 (rank : 13)
Query Neighborhood Hits	94	Target Neighborhood Hits	1333	Shared Neighborhood Hits	20
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

IFT74_HUMAN
NC score	0.027123 (rank : 61)	θ value	0.62314 (rank : 32)
Query Neighborhood Hits	94	Target Neighborhood Hits	949	Shared Neighborhood Hits	21
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

BAZ2B_HUMAN
NC score	0.026757 (rank : 62)	θ value	0.62314 (rank : 31)
Query Neighborhood Hits	94	Target Neighborhood Hits	803	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

MAML3_HUMAN
NC score	0.026639 (rank : 63)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	94	Target Neighborhood Hits	323	Shared Neighborhood Hits	17
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

NU214_HUMAN
NC score	0.024708 (rank : 64)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	94	Target Neighborhood Hits	657	Shared Neighborhood Hits	23
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

PELP1_HUMAN
NC score	0.024425 (rank : 65)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	94	Target Neighborhood Hits	596	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

MDM2_HUMAN
NC score	0.024060 (rank : 66)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	94	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	Q00987, Q13226, Q13297, Q13298, Q13299, Q13300, Q13301, Q53XW0, Q71TW9, Q9UGI3, Q9UMT8	Gene names	MDM2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2).

MAP2_HUMAN
NC score	0.023873 (rank : 67)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	94	Target Neighborhood Hits	348	Shared Neighborhood Hits	21
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

MYST3_HUMAN
NC score	0.023440 (rank : 68)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	94	Target Neighborhood Hits	772	Shared Neighborhood Hits	33
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

RP1L1_HUMAN
NC score	0.023415 (rank : 69)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	94	Target Neighborhood Hits	1072	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

HEM1_MOUSE
NC score	0.023322 (rank : 70)	θ value	0.813845 (rank : 34)
Query Neighborhood Hits	94	Target Neighborhood Hits	66	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VC19, Q64453	Gene names	Alas1
Domain Architecture	No domain graphic available
Description	5-aminolevulinate synthase, nonspecific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-H).

NFH_MOUSE
NC score	0.022095 (rank : 71)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	94	Target Neighborhood Hits	2247	Shared Neighborhood Hits	55
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MLL3_MOUSE
NC score	0.021863 (rank : 72)	θ value	1.81305 (rank : 45)
Query Neighborhood Hits	94	Target Neighborhood Hits	1399	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

TTBK1_HUMAN
NC score	0.021444 (rank : 73)	θ value	0.21417 (rank : 19)
Query Neighborhood Hits	94	Target Neighborhood Hits	1058	Shared Neighborhood Hits	24
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

DNL1_MOUSE
NC score	0.021164 (rank : 74)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	94	Target Neighborhood Hits	110	Shared Neighborhood Hits	11
SwissProt Accessions	P37913	Gene names	Lig1, Lig-1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

MPP10_HUMAN
NC score	0.020732 (rank : 75)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	94	Target Neighborhood Hits	306	Shared Neighborhood Hits	14
SwissProt Accessions	O00566	Gene names	MPHOSPH10, MPP10
Domain Architecture
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

MARCS_MOUSE
NC score	0.020731 (rank : 76)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	94	Target Neighborhood Hits	227	Shared Neighborhood Hits	11
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

SMRC2_HUMAN
NC score	0.019824 (rank : 77)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	94	Target Neighborhood Hits	499	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

KINH_HUMAN
NC score	0.017871 (rank : 78)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	94	Target Neighborhood Hits	1231	Shared Neighborhood Hits	27
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

ARI5B_HUMAN
NC score	0.017678 (rank : 79)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	94	Target Neighborhood Hits	328	Shared Neighborhood Hits	22
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

ZO1_HUMAN
NC score	0.016831 (rank : 80)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	94	Target Neighborhood Hits	474	Shared Neighborhood Hits	18
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

MILK1_MOUSE
NC score	0.016476 (rank : 81)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	94	Target Neighborhood Hits	788	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

CJ092_HUMAN
NC score	0.016206 (rank : 82)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	94	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IYW2, Q5JSF7, Q9NTQ5	Gene names	C10orf92
Domain Architecture	No domain graphic available
Description	Protein C10orf92.

PACE1_MOUSE
NC score	0.015658 (rank : 83)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	94	Target Neighborhood Hits	92	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DBQ7, Q6NY01, Q8BQC9, Q8BRJ1	Gene names	Scyl3, Pace1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

TRI25_HUMAN
NC score	0.015471 (rank : 84)	θ value	0.813845 (rank : 36)
Query Neighborhood Hits	94	Target Neighborhood Hits	472	Shared Neighborhood Hits	7
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

ESCO2_HUMAN
NC score	0.015429 (rank : 85)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	94	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q56NI9	Gene names	ESCO2
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO2 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 2) (ECO1 homolog 2).

CCD21_HUMAN
NC score	0.015079 (rank : 86)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	94	Target Neighborhood Hits	1228	Shared Neighborhood Hits	32
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

M4K4_MOUSE
NC score	0.014379 (rank : 87)	θ value	0.365318 (rank : 23)
Query Neighborhood Hits	94	Target Neighborhood Hits	1560	Shared Neighborhood Hits	28
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

JHD1B_HUMAN
NC score	0.014238 (rank : 88)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	94	Target Neighborhood Hits	178	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

M4K4_HUMAN
NC score	0.014054 (rank : 89)	θ value	0.47712 (rank : 27)
Query Neighborhood Hits	94	Target Neighborhood Hits	1589	Shared Neighborhood Hits	28
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

ZO1_MOUSE
NC score	0.013611 (rank : 90)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	94	Target Neighborhood Hits	453	Shared Neighborhood Hits	11
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

RSPO4_HUMAN
NC score	0.013347 (rank : 91)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	94	Target Neighborhood Hits	110	Shared Neighborhood Hits	2
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

TITIN_HUMAN
NC score	0.013227 (rank : 92)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	94	Target Neighborhood Hits	2923	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ZAN_HUMAN
NC score	0.013191 (rank : 93)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	94	Target Neighborhood Hits	679	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

CDYL_MOUSE
NC score	0.013054 (rank : 94)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	94	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WTK2	Gene names	Cdyl
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

PRGR_HUMAN
NC score	0.012952 (rank : 95)	θ value	0.813845 (rank : 35)
Query Neighborhood Hits	94	Target Neighborhood Hits	163	Shared Neighborhood Hits	5
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

XYLT1_HUMAN
NC score	0.012880 (rank : 96)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	94	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q86Y38, Q9H1B6	Gene names	XYLT1, XT1
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 1 (EC 2.4.2.26) (Xylosyltransferase I) (XylT-I) (XT-I) (Peptide O-xylosyltransferase 1).

E41L2_HUMAN
NC score	0.012603 (rank : 97)	θ value	1.38821 (rank : 39)
Query Neighborhood Hits	94	Target Neighborhood Hits	287	Shared Neighborhood Hits	12
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

SAPS1_MOUSE
NC score	0.012126 (rank : 98)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	94	Target Neighborhood Hits	144	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TSI3, Q80TJ4	Gene names	Saps1, Kiaa1115
Domain Architecture	No domain graphic available
Description	SAPS domain family member 1.

PAK1_HUMAN
NC score	0.011437 (rank : 99)	θ value	0.365318 (rank : 24)
Query Neighborhood Hits	94	Target Neighborhood Hits	873	Shared Neighborhood Hits	13
SwissProt Accessions	Q13153, O75561, Q13567, Q32M53, Q32M54, Q86W79	Gene names	PAK1
Domain Architecture
Description	Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK).

PAK1_MOUSE
NC score	0.011356 (rank : 100)	θ value	0.47712 (rank : 28)
Query Neighborhood Hits	94	Target Neighborhood Hits	878	Shared Neighborhood Hits	14
SwissProt Accessions	O88643	Gene names	Pak1, Paka
Domain Architecture
Description	Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) (CDC42/RAC effector kinase PAK-A).

SOX30_HUMAN
NC score	0.011281 (rank : 101)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	94	Target Neighborhood Hits	305	Shared Neighborhood Hits	11
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

MRCKB_HUMAN
NC score	0.009649 (rank : 102)	θ value	2.36792 (rank : 52)
Query Neighborhood Hits	94	Target Neighborhood Hits	2239	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

AAK1_MOUSE
NC score	0.009647 (rank : 103)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	94	Target Neighborhood Hits	1051	Shared Neighborhood Hits	23
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

UTRO_HUMAN
NC score	0.009267 (rank : 104)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	94	Target Neighborhood Hits	960	Shared Neighborhood Hits	19
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

TLE3_HUMAN
NC score	0.008970 (rank : 105)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	94	Target Neighborhood Hits	385	Shared Neighborhood Hits	10
SwissProt Accessions	Q04726, Q8IVV6, Q8WVR2, Q9HCM5	Gene names	TLE3, KIAA1547
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG3).

A2BP1_HUMAN
NC score	0.008354 (rank : 106)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	94	Target Neighborhood Hits	229	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NWB1, Q9NS20	Gene names	A2BP1, A2BP
Domain Architecture
Description	Ataxin-2-binding protein 1.

TLE3_MOUSE
NC score	0.007624 (rank : 107)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	94	Target Neighborhood Hits	378	Shared Neighborhood Hits	7
SwissProt Accessions	Q08122, Q923A4	Gene names	Tle3, Esg
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG) (Grg-3).

FGD5_HUMAN
NC score	0.006918 (rank : 108)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	94	Target Neighborhood Hits	235	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

CELR2_MOUSE
NC score	0.006087 (rank : 109)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	94	Target Neighborhood Hits	584	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

CELR2_HUMAN
NC score	0.005946 (rank : 110)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	94	Target Neighborhood Hits	657	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

ERBB2_HUMAN
NC score	0.004665 (rank : 111)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	94	Target Neighborhood Hits	1073	Shared Neighborhood Hits	16
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

PCDGK_HUMAN
NC score	0.003135 (rank : 112)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	94	Target Neighborhood Hits	162	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UN70, O60622, Q08192, Q9Y5C4	Gene names	PCDHGC3, PCDH2
Domain Architecture
Description	Protocadherin gamma C3 precursor (PCDH-gamma-C3) (Protocadherin 43) (PC-43) (Protocadherin 2).