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Network neighborhood for query Sequence : ESCO2_HUMAN

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ESCO2_HUMAN
SwissProt Accessions	Q56NI9	Gene names	ESCO2
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO2 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 2) (ECO1 homolog 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ESCO2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	45
SwissProt Accessions	Q56NI9	Gene names	ESCO2
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO2 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 2) (ECO1 homolog 2).

ESCO2_MOUSE
θ value	0 (rank : 2)	NC score	0.973741 (rank : 2)
Query Neighborhood Hits	45	Target Neighborhood Hits	29	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CIB9, Q3UMT6, Q6IQX5, Q8BNG9, Q8BQF8, Q9CRI8	Gene names	Esco2
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO2 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 2) (ECO1 homolog 2).

ESCO1_HUMAN
θ value	1.54831e-84 (rank : 3)	NC score	0.782385 (rank : 4)
Query Neighborhood Hits	45	Target Neighborhood Hits	361	Shared Neighborhood Hits	19
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

ESCO1_MOUSE
θ value	1.89267e-82 (rank : 4)	NC score	0.876655 (rank : 3)
Query Neighborhood Hits	45	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	Q69Z69, Q8BQI2, Q8BR47, Q922F5	Gene names	Esco1, Kiaa1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1).

TXND2_MOUSE
θ value	9.29e-05 (rank : 5)	NC score	0.090120 (rank : 5)
Query Neighborhood Hits	45	Target Neighborhood Hits	828	Shared Neighborhood Hits	20
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

CCNB3_HUMAN
θ value	0.00228821 (rank : 6)	NC score	0.064175 (rank : 8)
Query Neighborhood Hits	45	Target Neighborhood Hits	368	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WWL7, Q96SB5, Q96SB6, Q96SB7, Q9NT38	Gene names	CCNB3, CYCB3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

CHD9_HUMAN
θ value	0.00665767 (rank : 7)	NC score	0.051572 (rank : 12)
Query Neighborhood Hits	45	Target Neighborhood Hits	343	Shared Neighborhood Hits	14
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

AHTF1_HUMAN
θ value	0.0330416 (rank : 8)	NC score	0.072890 (rank : 6)
Query Neighborhood Hits	45	Target Neighborhood Hits	286	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WYP5, Q7Z4E3, Q8IZA4, Q96EH9, Q9Y4Q6	Gene names	AHCTF1, ELYS, TMBS62
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

CHD9_MOUSE
θ value	0.0431538 (rank : 9)	NC score	0.048246 (rank : 14)
Query Neighborhood Hits	45	Target Neighborhood Hits	427	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

PCLO_HUMAN
θ value	0.21417 (rank : 10)	NC score	0.033431 (rank : 19)
Query Neighborhood Hits	45	Target Neighborhood Hits	2046	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

TITIN_HUMAN
θ value	0.21417 (rank : 11)	NC score	0.019595 (rank : 33)
Query Neighborhood Hits	45	Target Neighborhood Hits	2923	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CI039_HUMAN
θ value	0.279714 (rank : 12)	NC score	0.037780 (rank : 17)
Query Neighborhood Hits	45	Target Neighborhood Hits	1171	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CCD39_MOUSE
θ value	0.47712 (rank : 13)	NC score	0.021273 (rank : 29)
Query Neighborhood Hits	45	Target Neighborhood Hits	1026	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

PTPRR_HUMAN
θ value	0.62314 (rank : 14)	NC score	0.014131 (rank : 40)
Query Neighborhood Hits	45	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

TACC1_MOUSE
θ value	0.813845 (rank : 15)	NC score	0.032198 (rank : 21)
Query Neighborhood Hits	45	Target Neighborhood Hits	667	Shared Neighborhood Hits	10
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

CIR_MOUSE
θ value	1.06291 (rank : 16)	NC score	0.071802 (rank : 7)
Query Neighborhood Hits	45	Target Neighborhood Hits	255	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

K1802_MOUSE
θ value	1.06291 (rank : 17)	NC score	0.015606 (rank : 36)
Query Neighborhood Hits	45	Target Neighborhood Hits	1596	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

TACC1_HUMAN
θ value	1.06291 (rank : 18)	NC score	0.032765 (rank : 20)
Query Neighborhood Hits	45	Target Neighborhood Hits	597	Shared Neighborhood Hits	10
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

RBCC1_MOUSE
θ value	1.38821 (rank : 19)	NC score	0.021228 (rank : 30)
Query Neighborhood Hits	45	Target Neighborhood Hits	1048	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

TBL2_HUMAN
θ value	1.38821 (rank : 20)	NC score	0.020043 (rank : 32)
Query Neighborhood Hits	45	Target Neighborhood Hits	225	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y4P3, Q9UQE2	Gene names	TBL2, WBSCR13
Domain Architecture
Description	Transducin beta-like 2 protein (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosome region 13 protein).

CDA7L_HUMAN
θ value	1.81305 (rank : 21)	NC score	0.027031 (rank : 25)
Query Neighborhood Hits	45	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q96GN5, Q6PIL4, Q86YT0, Q8IXN5, Q96C70, Q9H9A2, Q9NPV2	Gene names	CDCA7L, HR1, JPO2, R1
Domain Architecture	No domain graphic available
Description	Cell division cycle-associated 7-like protein (Protein JPO2) (Transcription factor RAM2).

CCD96_MOUSE
θ value	2.36792 (rank : 22)	NC score	0.026429 (rank : 27)
Query Neighborhood Hits	45	Target Neighborhood Hits	704	Shared Neighborhood Hits	16
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

MYST3_HUMAN
θ value	2.36792 (rank : 23)	NC score	0.027112 (rank : 24)
Query Neighborhood Hits	45	Target Neighborhood Hits	772	Shared Neighborhood Hits	19
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

HMMR_HUMAN
θ value	3.0926 (rank : 24)	NC score	0.028081 (rank : 23)
Query Neighborhood Hits	45	Target Neighborhood Hits	1082	Shared Neighborhood Hits	14
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

BRCA2_HUMAN
θ value	4.03905 (rank : 25)	NC score	0.030912 (rank : 22)
Query Neighborhood Hits	45	Target Neighborhood Hits	202	Shared Neighborhood Hits	10
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

CJ012_HUMAN
θ value	4.03905 (rank : 26)	NC score	0.037579 (rank : 18)
Query Neighborhood Hits	45	Target Neighborhood Hits	467	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

GASP2_MOUSE
θ value	4.03905 (rank : 27)	NC score	0.014499 (rank : 39)
Query Neighborhood Hits	45	Target Neighborhood Hits	228	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BUY8	Gene names	Gprasp2
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 2 (GASP-2).

PPIG_HUMAN
θ value	4.03905 (rank : 28)	NC score	0.026765 (rank : 26)
Query Neighborhood Hits	45	Target Neighborhood Hits	670	Shared Neighborhood Hits	15
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

PZRN4_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.009631 (rank : 44)
Query Neighborhood Hits	45	Target Neighborhood Hits	438	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

FA13C_HUMAN
θ value	5.27518 (rank : 30)	NC score	0.015429 (rank : 37)
Query Neighborhood Hits	45	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

MSH3_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.012262 (rank : 41)
Query Neighborhood Hits	45	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	P20585, Q6PJT5, Q86UQ6, Q92867	Gene names	MSH3, DUC1, DUG
Domain Architecture
Description	DNA mismatch repair protein Msh3 (Divergent upstream protein) (DUP) (Mismatch repair protein 1) (MRP1).

PO6F1_MOUSE
θ value	5.27518 (rank : 32)	NC score	0.008054 (rank : 46)
Query Neighborhood Hits	45	Target Neighborhood Hits	581	Shared Neighborhood Hits	5
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

RBBP6_MOUSE
θ value	5.27518 (rank : 33)	NC score	0.042548 (rank : 15)
Query Neighborhood Hits	45	Target Neighborhood Hits	1014	Shared Neighborhood Hits	22
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

SEBP2_HUMAN
θ value	5.27518 (rank : 34)	NC score	0.019559 (rank : 34)
Query Neighborhood Hits	45	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q96T21, Q8IYC0	Gene names	SECISBP2, SBP2
Domain Architecture
Description	SECIS-binding protein 2 (Selenocysteine insertion sequence-binding protein 2).

SSH2_HUMAN
θ value	5.27518 (rank : 35)	NC score	0.010476 (rank : 43)
Query Neighborhood Hits	45	Target Neighborhood Hits	140	Shared Neighborhood Hits	4
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

TEX14_HUMAN
θ value	5.27518 (rank : 36)	NC score	0.007241 (rank : 47)
Query Neighborhood Hits	45	Target Neighborhood Hits	1103	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

ATRX_MOUSE
θ value	6.88961 (rank : 37)	NC score	0.026327 (rank : 28)
Query Neighborhood Hits	45	Target Neighborhood Hits	682	Shared Neighborhood Hits	18
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

CG010_HUMAN
θ value	6.88961 (rank : 38)	NC score	0.015323 (rank : 38)
Query Neighborhood Hits	45	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HAC7, Q8TE00, Q8TEY1	Gene names	C7orf10, DERP13
Domain Architecture	No domain graphic available
Description	Protein C7orf10 (Dermal papilla-derived protein 13).

DEK_MOUSE
θ value	6.88961 (rank : 39)	NC score	0.058165 (rank : 10)
Query Neighborhood Hits	45	Target Neighborhood Hits	280	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

MPP10_MOUSE
θ value	6.88961 (rank : 40)	NC score	0.020626 (rank : 31)
Query Neighborhood Hits	45	Target Neighborhood Hits	251	Shared Neighborhood Hits	9
SwissProt Accessions	Q810V0	Gene names	Mphosph10
Domain Architecture	No domain graphic available
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

NIPBL_HUMAN
θ value	6.88961 (rank : 41)	NC score	0.038967 (rank : 16)
Query Neighborhood Hits	45	Target Neighborhood Hits	1311	Shared Neighborhood Hits	23
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

SDCG1_MOUSE
θ value	6.88961 (rank : 42)	NC score	0.018053 (rank : 35)
Query Neighborhood Hits	45	Target Neighborhood Hits	168	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CCP0, Q66JX6, Q8C9R6, Q8CA65, Q8JZT9, Q8R072, Q9CW30, Q9CYB8, Q9D4A9	Gene names	Sdccag1
Domain Architecture
Description	Serologically defined colon cancer antigen 1.

ZN181_HUMAN
θ value	6.88961 (rank : 43)	NC score	-0.000892 (rank : 48)
Query Neighborhood Hits	45	Target Neighborhood Hits	764	Shared Neighborhood Hits	3
SwissProt Accessions	Q2M3W8, Q49A75	Gene names	ZNF181
Domain Architecture	No domain graphic available
Description	Zinc finger protein 181 (HHZ181).

ATAD2_HUMAN
θ value	8.99809 (rank : 44)	NC score	0.010815 (rank : 42)
Query Neighborhood Hits	45	Target Neighborhood Hits	322	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

MYO5A_MOUSE
θ value	8.99809 (rank : 45)	NC score	0.009565 (rank : 45)
Query Neighborhood Hits	45	Target Neighborhood Hits	1117	Shared Neighborhood Hits	16
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

MAP1B_MOUSE
θ value	θ > 10 (rank : 46)	NC score	0.050478 (rank : 13)
Query Neighborhood Hits	45	Target Neighborhood Hits	977	Shared Neighborhood Hits	21
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

TRDN_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.060333 (rank : 9)
Query Neighborhood Hits	45	Target Neighborhood Hits	542	Shared Neighborhood Hits	18
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

ZCH10_MOUSE
θ value	θ > 10 (rank : 48)	NC score	0.055694 (rank : 11)
Query Neighborhood Hits	45	Target Neighborhood Hits	133	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

Hits sorted by NC score

ESCO2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	45
SwissProt Accessions	Q56NI9	Gene names	ESCO2
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO2 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 2) (ECO1 homolog 2).

ESCO2_MOUSE
NC score	0.973741 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	45	Target Neighborhood Hits	29	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CIB9, Q3UMT6, Q6IQX5, Q8BNG9, Q8BQF8, Q9CRI8	Gene names	Esco2
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO2 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 2) (ECO1 homolog 2).

ESCO1_MOUSE
NC score	0.876655 (rank : 3)	θ value	1.89267e-82 (rank : 4)
Query Neighborhood Hits	45	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	Q69Z69, Q8BQI2, Q8BR47, Q922F5	Gene names	Esco1, Kiaa1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1).

ESCO1_HUMAN
NC score	0.782385 (rank : 4)	θ value	1.54831e-84 (rank : 3)
Query Neighborhood Hits	45	Target Neighborhood Hits	361	Shared Neighborhood Hits	19
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

TXND2_MOUSE
NC score	0.090120 (rank : 5)	θ value	9.29e-05 (rank : 5)
Query Neighborhood Hits	45	Target Neighborhood Hits	828	Shared Neighborhood Hits	20
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

AHTF1_HUMAN
NC score	0.072890 (rank : 6)	θ value	0.0330416 (rank : 8)
Query Neighborhood Hits	45	Target Neighborhood Hits	286	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WYP5, Q7Z4E3, Q8IZA4, Q96EH9, Q9Y4Q6	Gene names	AHCTF1, ELYS, TMBS62
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

CIR_MOUSE
NC score	0.071802 (rank : 7)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	45	Target Neighborhood Hits	255	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

CCNB3_HUMAN
NC score	0.064175 (rank : 8)	θ value	0.00228821 (rank : 6)
Query Neighborhood Hits	45	Target Neighborhood Hits	368	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WWL7, Q96SB5, Q96SB6, Q96SB7, Q9NT38	Gene names	CCNB3, CYCB3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

TRDN_HUMAN
NC score	0.060333 (rank : 9)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	45	Target Neighborhood Hits	542	Shared Neighborhood Hits	18
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

DEK_MOUSE
NC score	0.058165 (rank : 10)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	45	Target Neighborhood Hits	280	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

ZCH10_MOUSE
NC score	0.055694 (rank : 11)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	45	Target Neighborhood Hits	133	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

CHD9_HUMAN
NC score	0.051572 (rank : 12)	θ value	0.00665767 (rank : 7)
Query Neighborhood Hits	45	Target Neighborhood Hits	343	Shared Neighborhood Hits	14
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

MAP1B_MOUSE
NC score	0.050478 (rank : 13)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	45	Target Neighborhood Hits	977	Shared Neighborhood Hits	21
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

CHD9_MOUSE
NC score	0.048246 (rank : 14)	θ value	0.0431538 (rank : 9)
Query Neighborhood Hits	45	Target Neighborhood Hits	427	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

RBBP6_MOUSE
NC score	0.042548 (rank : 15)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	45	Target Neighborhood Hits	1014	Shared Neighborhood Hits	22
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

NIPBL_HUMAN
NC score	0.038967 (rank : 16)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	45	Target Neighborhood Hits	1311	Shared Neighborhood Hits	23
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

CI039_HUMAN
NC score	0.037780 (rank : 17)	θ value	0.279714 (rank : 12)
Query Neighborhood Hits	45	Target Neighborhood Hits	1171	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CJ012_HUMAN
NC score	0.037579 (rank : 18)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	45	Target Neighborhood Hits	467	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

PCLO_HUMAN
NC score	0.033431 (rank : 19)	θ value	0.21417 (rank : 10)
Query Neighborhood Hits	45	Target Neighborhood Hits	2046	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

TACC1_HUMAN
NC score	0.032765 (rank : 20)	θ value	1.06291 (rank : 18)
Query Neighborhood Hits	45	Target Neighborhood Hits	597	Shared Neighborhood Hits	10
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

TACC1_MOUSE
NC score	0.032198 (rank : 21)	θ value	0.813845 (rank : 15)
Query Neighborhood Hits	45	Target Neighborhood Hits	667	Shared Neighborhood Hits	10
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

BRCA2_HUMAN
NC score	0.030912 (rank : 22)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	45	Target Neighborhood Hits	202	Shared Neighborhood Hits	10
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

HMMR_HUMAN
NC score	0.028081 (rank : 23)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	45	Target Neighborhood Hits	1082	Shared Neighborhood Hits	14
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

MYST3_HUMAN
NC score	0.027112 (rank : 24)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	45	Target Neighborhood Hits	772	Shared Neighborhood Hits	19
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

CDA7L_HUMAN
NC score	0.027031 (rank : 25)	θ value	1.81305 (rank : 21)
Query Neighborhood Hits	45	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q96GN5, Q6PIL4, Q86YT0, Q8IXN5, Q96C70, Q9H9A2, Q9NPV2	Gene names	CDCA7L, HR1, JPO2, R1
Domain Architecture	No domain graphic available
Description	Cell division cycle-associated 7-like protein (Protein JPO2) (Transcription factor RAM2).

PPIG_HUMAN
NC score	0.026765 (rank : 26)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	45	Target Neighborhood Hits	670	Shared Neighborhood Hits	15
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

CCD96_MOUSE
NC score	0.026429 (rank : 27)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	45	Target Neighborhood Hits	704	Shared Neighborhood Hits	16
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

ATRX_MOUSE
NC score	0.026327 (rank : 28)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	45	Target Neighborhood Hits	682	Shared Neighborhood Hits	18
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

CCD39_MOUSE
NC score	0.021273 (rank : 29)	θ value	0.47712 (rank : 13)
Query Neighborhood Hits	45	Target Neighborhood Hits	1026	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

RBCC1_MOUSE
NC score	0.021228 (rank : 30)	θ value	1.38821 (rank : 19)
Query Neighborhood Hits	45	Target Neighborhood Hits	1048	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

MPP10_MOUSE
NC score	0.020626 (rank : 31)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	45	Target Neighborhood Hits	251	Shared Neighborhood Hits	9
SwissProt Accessions	Q810V0	Gene names	Mphosph10
Domain Architecture	No domain graphic available
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

TBL2_HUMAN
NC score	0.020043 (rank : 32)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	45	Target Neighborhood Hits	225	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y4P3, Q9UQE2	Gene names	TBL2, WBSCR13
Domain Architecture
Description	Transducin beta-like 2 protein (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosome region 13 protein).

TITIN_HUMAN
NC score	0.019595 (rank : 33)	θ value	0.21417 (rank : 11)
Query Neighborhood Hits	45	Target Neighborhood Hits	2923	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

SEBP2_HUMAN
NC score	0.019559 (rank : 34)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	45	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q96T21, Q8IYC0	Gene names	SECISBP2, SBP2
Domain Architecture
Description	SECIS-binding protein 2 (Selenocysteine insertion sequence-binding protein 2).

SDCG1_MOUSE
NC score	0.018053 (rank : 35)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	45	Target Neighborhood Hits	168	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CCP0, Q66JX6, Q8C9R6, Q8CA65, Q8JZT9, Q8R072, Q9CW30, Q9CYB8, Q9D4A9	Gene names	Sdccag1
Domain Architecture
Description	Serologically defined colon cancer antigen 1.

K1802_MOUSE
NC score	0.015606 (rank : 36)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	45	Target Neighborhood Hits	1596	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

FA13C_HUMAN
NC score	0.015429 (rank : 37)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	45	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

CG010_HUMAN
NC score	0.015323 (rank : 38)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	45	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HAC7, Q8TE00, Q8TEY1	Gene names	C7orf10, DERP13
Domain Architecture	No domain graphic available
Description	Protein C7orf10 (Dermal papilla-derived protein 13).

GASP2_MOUSE
NC score	0.014499 (rank : 39)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	45	Target Neighborhood Hits	228	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BUY8	Gene names	Gprasp2
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 2 (GASP-2).

PTPRR_HUMAN
NC score	0.014131 (rank : 40)	θ value	0.62314 (rank : 14)
Query Neighborhood Hits	45	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

MSH3_HUMAN
NC score	0.012262 (rank : 41)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	45	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	P20585, Q6PJT5, Q86UQ6, Q92867	Gene names	MSH3, DUC1, DUG
Domain Architecture
Description	DNA mismatch repair protein Msh3 (Divergent upstream protein) (DUP) (Mismatch repair protein 1) (MRP1).

ATAD2_HUMAN
NC score	0.010815 (rank : 42)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	45	Target Neighborhood Hits	322	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

SSH2_HUMAN
NC score	0.010476 (rank : 43)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	45	Target Neighborhood Hits	140	Shared Neighborhood Hits	4
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

PZRN4_HUMAN
NC score	0.009631 (rank : 44)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	45	Target Neighborhood Hits	438	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

MYO5A_MOUSE
NC score	0.009565 (rank : 45)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	45	Target Neighborhood Hits	1117	Shared Neighborhood Hits	16
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

PO6F1_MOUSE
NC score	0.008054 (rank : 46)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	45	Target Neighborhood Hits	581	Shared Neighborhood Hits	5
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

TEX14_HUMAN
NC score	0.007241 (rank : 47)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	45	Target Neighborhood Hits	1103	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

ZN181_HUMAN
NC score	-0.000892 (rank : 48)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	45	Target Neighborhood Hits	764	Shared Neighborhood Hits	3
SwissProt Accessions	Q2M3W8, Q49A75	Gene names	ZNF181
Domain Architecture	No domain graphic available
Description	Zinc finger protein 181 (HHZ181).