Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : RHG18_HUMAN

For an explanation of this page, click here

RHG18_HUMAN
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RHG18_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	90	Target Neighborhood Hits	90	Shared Neighborhood Hits	90
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

RHG18_MOUSE
θ value	0 (rank : 2)	NC score	0.987326 (rank : 2)
Query Neighborhood Hits	90	Target Neighborhood Hits	110	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG07_MOUSE
θ value	1.09232e-21 (rank : 3)	NC score	0.758744 (rank : 12)
Query Neighborhood Hits	90	Target Neighborhood Hits	103	Shared Neighborhood Hits	60
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG07_HUMAN
θ value	9.24701e-21 (rank : 4)	NC score	0.753927 (rank : 13)
Query Neighborhood Hits	90	Target Neighborhood Hits	108	Shared Neighborhood Hits	60
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

MYO9B_HUMAN
θ value	8.10077e-17 (rank : 5)	NC score	0.407466 (rank : 58)
Query Neighborhood Hits	90	Target Neighborhood Hits	641	Shared Neighborhood Hits	61
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_MOUSE
θ value	1.38178e-16 (rank : 6)	NC score	0.413054 (rank : 57)
Query Neighborhood Hits	90	Target Neighborhood Hits	311	Shared Neighborhood Hits	62
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

RBP1_MOUSE
θ value	1.38178e-16 (rank : 7)	NC score	0.724453 (rank : 19)
Query Neighborhood Hits	90	Target Neighborhood Hits	493	Shared Neighborhood Hits	70
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RHG12_MOUSE
θ value	1.38178e-16 (rank : 8)	NC score	0.767706 (rank : 7)
Query Neighborhood Hits	90	Target Neighborhood Hits	204	Shared Neighborhood Hits	60
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_HUMAN
θ value	1.80466e-16 (rank : 9)	NC score	0.771914 (rank : 6)
Query Neighborhood Hits	90	Target Neighborhood Hits	190	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RBP1_HUMAN
θ value	3.07829e-16 (rank : 10)	NC score	0.704603 (rank : 28)
Query Neighborhood Hits	90	Target Neighborhood Hits	521	Shared Neighborhood Hits	70
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

STA13_HUMAN
θ value	8.95645e-16 (rank : 11)	NC score	0.715308 (rank : 20)
Query Neighborhood Hits	90	Target Neighborhood Hits	89	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

ABR_HUMAN
θ value	2.60593e-15 (rank : 12)	NC score	0.693869 (rank : 30)
Query Neighborhood Hits	90	Target Neighborhood Hits	166	Shared Neighborhood Hits	60
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

3BP1_HUMAN
θ value	6.41864e-14 (rank : 13)	NC score	0.753504 (rank : 14)
Query Neighborhood Hits	90	Target Neighborhood Hits	376	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

STA13_MOUSE
θ value	6.41864e-14 (rank : 14)	NC score	0.704890 (rank : 27)
Query Neighborhood Hits	90	Target Neighborhood Hits	89	Shared Neighborhood Hits	58
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

GMIP_HUMAN
θ value	1.86753e-13 (rank : 15)	NC score	0.763814 (rank : 10)
Query Neighborhood Hits	90	Target Neighborhood Hits	225	Shared Neighborhood Hits	61
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GMIP_MOUSE
θ value	4.16044e-13 (rank : 16)	NC score	0.765847 (rank : 9)
Query Neighborhood Hits	90	Target Neighborhood Hits	202	Shared Neighborhood Hits	61
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RHG06_HUMAN
θ value	7.09661e-13 (rank : 17)	NC score	0.778129 (rank : 4)
Query Neighborhood Hits	90	Target Neighborhood Hits	114	Shared Neighborhood Hits	61
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RGAP1_HUMAN
θ value	9.26847e-13 (rank : 18)	NC score	0.762627 (rank : 11)
Query Neighborhood Hits	90	Target Neighborhood Hits	189	Shared Neighborhood Hits	61
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG26_HUMAN
θ value	9.26847e-13 (rank : 19)	NC score	0.682144 (rank : 33)
Query Neighborhood Hits	90	Target Neighborhood Hits	281	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

STAR8_HUMAN
θ value	2.0648e-12 (rank : 20)	NC score	0.697666 (rank : 29)
Query Neighborhood Hits	90	Target Neighborhood Hits	216	Shared Neighborhood Hits	58
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

CEND3_HUMAN
θ value	2.69671e-12 (rank : 21)	NC score	0.578270 (rank : 54)
Query Neighborhood Hits	90	Target Neighborhood Hits	275	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

RHG06_MOUSE
θ value	2.69671e-12 (rank : 22)	NC score	0.776791 (rank : 5)
Query Neighborhood Hits	90	Target Neighborhood Hits	105	Shared Neighborhood Hits	60
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

CHIO_MOUSE
θ value	3.52202e-12 (rank : 23)	NC score	0.714100 (rank : 21)
Query Neighborhood Hits	90	Target Neighborhood Hits	130	Shared Neighborhood Hits	59
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

STAR8_MOUSE
θ value	3.52202e-12 (rank : 24)	NC score	0.706411 (rank : 26)
Query Neighborhood Hits	90	Target Neighborhood Hits	101	Shared Neighborhood Hits	58
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

CEND3_MOUSE
θ value	4.59992e-12 (rank : 25)	NC score	0.586559 (rank : 52)
Query Neighborhood Hits	90	Target Neighborhood Hits	228	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CHIO_HUMAN
θ value	7.84624e-12 (rank : 26)	NC score	0.680908 (rank : 35)
Query Neighborhood Hits	90	Target Neighborhood Hits	220	Shared Neighborhood Hits	59
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

RHG01_HUMAN
θ value	2.28291e-11 (rank : 27)	NC score	0.744148 (rank : 16)
Query Neighborhood Hits	90	Target Neighborhood Hits	75	Shared Neighborhood Hits	60
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

RHG09_HUMAN
θ value	2.28291e-11 (rank : 28)	NC score	0.779803 (rank : 3)
Query Neighborhood Hits	90	Target Neighborhood Hits	186	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

CHIN_HUMAN
θ value	2.98157e-11 (rank : 29)	NC score	0.681554 (rank : 34)
Query Neighborhood Hits	90	Target Neighborhood Hits	227	Shared Neighborhood Hits	59
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

3BP1_MOUSE
θ value	5.08577e-11 (rank : 30)	NC score	0.767309 (rank : 8)
Query Neighborhood Hits	90	Target Neighborhood Hits	238	Shared Neighborhood Hits	60
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RHG25_HUMAN
θ value	8.67504e-11 (rank : 31)	NC score	0.663949 (rank : 39)
Query Neighborhood Hits	90	Target Neighborhood Hits	550	Shared Neighborhood Hits	66
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CHIN_MOUSE
θ value	1.133e-10 (rank : 32)	NC score	0.680289 (rank : 36)
Query Neighborhood Hits	90	Target Neighborhood Hits	229	Shared Neighborhood Hits	60
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

GRLF1_HUMAN
θ value	1.133e-10 (rank : 33)	NC score	0.729330 (rank : 17)
Query Neighborhood Hits	90	Target Neighborhood Hits	167	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

K1688_MOUSE
θ value	1.133e-10 (rank : 34)	NC score	0.593796 (rank : 51)
Query Neighborhood Hits	90	Target Neighborhood Hits	188	Shared Neighborhood Hits	57
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

OPHN1_MOUSE
θ value	1.133e-10 (rank : 35)	NC score	0.709029 (rank : 24)
Query Neighborhood Hits	90	Target Neighborhood Hits	174	Shared Neighborhood Hits	60
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

TCGAP_HUMAN
θ value	1.133e-10 (rank : 36)	NC score	0.630850 (rank : 44)
Query Neighborhood Hits	90	Target Neighborhood Hits	872	Shared Neighborhood Hits	63
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCGAP_MOUSE
θ value	1.133e-10 (rank : 37)	NC score	0.710218 (rank : 23)
Query Neighborhood Hits	90	Target Neighborhood Hits	409	Shared Neighborhood Hits	60
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

K1688_HUMAN
θ value	1.47974e-10 (rank : 38)	NC score	0.580052 (rank : 53)
Query Neighborhood Hits	90	Target Neighborhood Hits	217	Shared Neighborhood Hits	58
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

RHG08_MOUSE
θ value	1.47974e-10 (rank : 39)	NC score	0.724505 (rank : 18)
Query Neighborhood Hits	90	Target Neighborhood Hits	73	Shared Neighborhood Hits	60
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

CEND2_HUMAN
θ value	1.9326e-10 (rank : 40)	NC score	0.604772 (rank : 50)
Query Neighborhood Hits	90	Target Neighborhood Hits	166	Shared Neighborhood Hits	58
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

OPHN1_HUMAN
θ value	1.9326e-10 (rank : 41)	NC score	0.708284 (rank : 25)
Query Neighborhood Hits	90	Target Neighborhood Hits	161	Shared Neighborhood Hits	60
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

RHG25_MOUSE
θ value	1.9326e-10 (rank : 42)	NC score	0.682555 (rank : 32)
Query Neighborhood Hits	90	Target Neighborhood Hits	492	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RGAP1_MOUSE
θ value	4.30538e-10 (rank : 43)	NC score	0.750594 (rank : 15)
Query Neighborhood Hits	90	Target Neighborhood Hits	185	Shared Neighborhood Hits	61
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG08_HUMAN
θ value	1.63604e-09 (rank : 44)	NC score	0.714054 (rank : 22)
Query Neighborhood Hits	90	Target Neighborhood Hits	88	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

BCR_HUMAN
θ value	6.21693e-09 (rank : 45)	NC score	0.671531 (rank : 38)
Query Neighborhood Hits	90	Target Neighborhood Hits	204	Shared Neighborhood Hits	60
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

CE005_MOUSE
θ value	6.21693e-09 (rank : 46)	NC score	0.618616 (rank : 47)
Query Neighborhood Hits	90	Target Neighborhood Hits	238	Shared Neighborhood Hits	65
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

RHG05_MOUSE
θ value	8.11959e-09 (rank : 47)	NC score	0.686918 (rank : 31)
Query Neighborhood Hits	90	Target Neighborhood Hits	165	Shared Neighborhood Hits	64
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

CE005_HUMAN
θ value	1.06045e-08 (rank : 48)	NC score	0.620193 (rank : 46)
Query Neighborhood Hits	90	Target Neighborhood Hits	213	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

RHG04_HUMAN
θ value	4.0297e-08 (rank : 49)	NC score	0.651206 (rank : 42)
Query Neighborhood Hits	90	Target Neighborhood Hits	307	Shared Neighborhood Hits	62
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RHG05_HUMAN
θ value	4.0297e-08 (rank : 50)	NC score	0.674161 (rank : 37)
Query Neighborhood Hits	90	Target Neighborhood Hits	158	Shared Neighborhood Hits	63
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

SRGP2_HUMAN
θ value	4.0297e-08 (rank : 51)	NC score	0.632943 (rank : 43)
Query Neighborhood Hits	90	Target Neighborhood Hits	331	Shared Neighborhood Hits	61
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

SRGP2_MOUSE
θ value	8.97725e-08 (rank : 52)	NC score	0.623985 (rank : 45)
Query Neighborhood Hits	90	Target Neighborhood Hits	324	Shared Neighborhood Hits	62
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

FNBP2_HUMAN
θ value	1.99992e-07 (rank : 53)	NC score	0.615601 (rank : 48)
Query Neighborhood Hits	90	Target Neighborhood Hits	432	Shared Neighborhood Hits	65
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

CEND1_MOUSE
θ value	3.41135e-07 (rank : 54)	NC score	0.506620 (rank : 55)
Query Neighborhood Hits	90	Target Neighborhood Hits	260	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CEND1_HUMAN
θ value	9.92553e-07 (rank : 55)	NC score	0.486114 (rank : 56)
Query Neighborhood Hits	90	Target Neighborhood Hits	284	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

SRGP1_HUMAN
θ value	3.77169e-06 (rank : 56)	NC score	0.610653 (rank : 49)
Query Neighborhood Hits	90	Target Neighborhood Hits	390	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

TAGAP_MOUSE
θ value	9.29e-05 (rank : 57)	NC score	0.656129 (rank : 40)
Query Neighborhood Hits	90	Target Neighborhood Hits	83	Shared Neighborhood Hits	58
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

TAGAP_HUMAN
θ value	0.000786445 (rank : 58)	NC score	0.651433 (rank : 41)
Query Neighborhood Hits	90	Target Neighborhood Hits	82	Shared Neighborhood Hits	57
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

P85A_HUMAN
θ value	0.00102713 (rank : 59)	NC score	0.319128 (rank : 59)
Query Neighborhood Hits	90	Target Neighborhood Hits	479	Shared Neighborhood Hits	59
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

I5P2_HUMAN
θ value	0.00390308 (rank : 60)	NC score	0.305335 (rank : 61)
Query Neighborhood Hits	90	Target Neighborhood Hits	86	Shared Neighborhood Hits	50
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

FACD2_HUMAN
θ value	0.0330416 (rank : 61)	NC score	0.066352 (rank : 70)
Query Neighborhood Hits	90	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BXW9, Q2LA86, Q69YP9, Q6PJN7, Q9BQ06, Q9H9T9	Gene names	FANCD2
Domain Architecture	No domain graphic available
Description	Fanconi anemia group D2 protein (Protein FACD2).

RABE1_HUMAN
θ value	0.0736092 (rank : 62)	NC score	0.025276 (rank : 90)
Query Neighborhood Hits	90	Target Neighborhood Hits	1104	Shared Neighborhood Hits	20
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

ROCK1_HUMAN
θ value	0.279714 (rank : 63)	NC score	0.006144 (rank : 111)
Query Neighborhood Hits	90	Target Neighborhood Hits	2000	Shared Neighborhood Hits	21
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

FLIP1_HUMAN
θ value	0.365318 (rank : 64)	NC score	0.016137 (rank : 97)
Query Neighborhood Hits	90	Target Neighborhood Hits	1405	Shared Neighborhood Hits	18
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

5NT1B_MOUSE
θ value	1.06291 (rank : 65)	NC score	0.022472 (rank : 92)
Query Neighborhood Hits	90	Target Neighborhood Hits	78	Shared Neighborhood Hits	2
SwissProt Accessions	Q91YE9, Q91Y48	Gene names	Nt5c1b, Airp
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

DAPK3_HUMAN
θ value	1.06291 (rank : 66)	NC score	-0.002577 (rank : 117)
Query Neighborhood Hits	90	Target Neighborhood Hits	945	Shared Neighborhood Hits	5
SwissProt Accessions	O43293	Gene names	DAPK3, ZIPK
Domain Architecture
Description	Death-associated protein kinase 3 (EC 2.7.11.1) (DAP kinase 3) (DAP- like kinase) (Dlk) (ZIP-kinase).

IF4G1_HUMAN
θ value	1.06291 (rank : 67)	NC score	0.017646 (rank : 96)
Query Neighborhood Hits	90	Target Neighborhood Hits	347	Shared Neighborhood Hits	5
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

DBLOH_MOUSE
θ value	1.81305 (rank : 68)	NC score	0.030717 (rank : 89)
Query Neighborhood Hits	90	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIQ3, Q9CZD1, Q9DCD3	Gene names	Diablo, Smac
Domain Architecture	No domain graphic available
Description	Diablo homolog, mitochondrial precursor (Second mitochondria-derived activator of caspase) (Smac protein) (Direct IAP-binding protein with low pI).

GOGA4_MOUSE
θ value	1.81305 (rank : 69)	NC score	0.014202 (rank : 98)
Query Neighborhood Hits	90	Target Neighborhood Hits	1939	Shared Neighborhood Hits	22
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

KI21B_HUMAN
θ value	1.81305 (rank : 70)	NC score	0.007173 (rank : 108)
Query Neighborhood Hits	90	Target Neighborhood Hits	1017	Shared Neighborhood Hits	15
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

MCM4_MOUSE
θ value	1.81305 (rank : 71)	NC score	0.018984 (rank : 95)
Query Neighborhood Hits	90	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	P49717, O89056	Gene names	Mcm4, Cdc21, Mcmd4
Domain Architecture
Description	DNA replication licensing factor MCM4 (CDC21 homolog) (P1-CDC21).

SMCA4_HUMAN
θ value	1.81305 (rank : 72)	NC score	0.008484 (rank : 106)
Query Neighborhood Hits	90	Target Neighborhood Hits	597	Shared Neighborhood Hits	9
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

KPBB_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.010172 (rank : 104)
Query Neighborhood Hits	90	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TSH2	Gene names	Phkb
Domain Architecture	No domain graphic available
Description	Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta).

MCM4_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.013549 (rank : 100)
Query Neighborhood Hits	90	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	P33991, Q8NEH1, Q99658	Gene names	MCM4, CDC21
Domain Architecture
Description	DNA replication licensing factor MCM4 (CDC21 homolog) (P1-CDC21).

NIN_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.022103 (rank : 93)
Query Neighborhood Hits	90	Target Neighborhood Hits	1416	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

RAE2_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.013703 (rank : 99)
Query Neighborhood Hits	90	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P26374, Q9H1Y4	Gene names	CHML, REP2
Domain Architecture
Description	Rab proteins geranylgeranyltransferase component A 2 (Rab escort protein 2) (REP-2) (Choroideraemia-like protein).

RBL1_MOUSE
θ value	5.27518 (rank : 77)	NC score	0.008603 (rank : 105)
Query Neighborhood Hits	90	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q64701	Gene names	Rbl1
Domain Architecture
Description	Retinoblastoma-like protein 1 (107 kDa retinoblastoma-associated protein) (PRB1) (P107).

SMRCD_MOUSE
θ value	5.27518 (rank : 78)	NC score	0.006536 (rank : 109)
Query Neighborhood Hits	90	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

DBLOH_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.023731 (rank : 91)
Query Neighborhood Hits	90	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR28, Q96LV0, Q9BT11, Q9HAV6	Gene names	DIABLO, SMAC
Domain Architecture	No domain graphic available
Description	Diablo homolog, mitochondrial precursor (Second mitochondria-derived activator of caspase) (Smac protein) (Direct IAP-binding protein with low pI).

PAR14_MOUSE
θ value	6.88961 (rank : 80)	NC score	0.008333 (rank : 107)
Query Neighborhood Hits	90	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

RABE1_MOUSE
θ value	6.88961 (rank : 81)	NC score	0.019800 (rank : 94)
Query Neighborhood Hits	90	Target Neighborhood Hits	1105	Shared Neighborhood Hits	20
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

RPGF6_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.005874 (rank : 112)
Query Neighborhood Hits	90	Target Neighborhood Hits	266	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

WNK4_HUMAN
θ value	6.88961 (rank : 83)	NC score	-0.002275 (rank : 116)
Query Neighborhood Hits	90	Target Neighborhood Hits	1043	Shared Neighborhood Hits	7
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

COG8_MOUSE
θ value	8.99809 (rank : 84)	NC score	0.011591 (rank : 103)
Query Neighborhood Hits	90	Target Neighborhood Hits	147	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JJA2	Gene names	Cog8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

GOGA5_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.013522 (rank : 101)
Query Neighborhood Hits	90	Target Neighborhood Hits	1434	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

ITB2_HUMAN
θ value	8.99809 (rank : 86)	NC score	0.001116 (rank : 115)
Query Neighborhood Hits	90	Target Neighborhood Hits	282	Shared Neighborhood Hits	2
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

KI21B_MOUSE
θ value	8.99809 (rank : 87)	NC score	0.006229 (rank : 110)
Query Neighborhood Hits	90	Target Neighborhood Hits	997	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

KLHL6_MOUSE
θ value	8.99809 (rank : 88)	NC score	0.001420 (rank : 114)
Query Neighborhood Hits	90	Target Neighborhood Hits	186	Shared Neighborhood Hits	3
SwissProt Accessions	Q6V595	Gene names	Klhl6
Domain Architecture	No domain graphic available
Description	Kelch-like protein 6.

PRAX_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.004814 (rank : 113)
Query Neighborhood Hits	90	Target Neighborhood Hits	215	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

TRIPB_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.012616 (rank : 102)
Query Neighborhood Hits	90	Target Neighborhood Hits	1587	Shared Neighborhood Hits	22
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

ATCAY_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.050505 (rank : 88)
Query Neighborhood Hits	90	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q86WG3, Q8NAQ2, Q8TAQ3, Q96HC6, Q96JF5	Gene names	ATCAY, KIAA1872
Domain Architecture
Description	Caytaxin (Ataxia Cayman type protein) (BNIP-H).

ATCAY_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.050965 (rank : 87)
Query Neighborhood Hits	90	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHE3, Q3TR94	Gene names	Atcay
Domain Architecture
Description	Caytaxin.

BNIP2_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.053614 (rank : 77)
Query Neighborhood Hits	90	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q12982	Gene names	BNIP2, NIP2
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

BNIP2_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.053528 (rank : 78)
Query Neighborhood Hits	90	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	O54940	Gene names	Bnip2, Nip2l
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

CENA1_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.051319 (rank : 85)
Query Neighborhood Hits	90	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CENA2_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.054774 (rank : 73)
Query Neighborhood Hits	90	Target Neighborhood Hits	83	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CENB1_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.070211 (rank : 68)
Query Neighborhood Hits	90	Target Neighborhood Hits	383	Shared Neighborhood Hits	11
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB2_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.076308 (rank : 65)
Query Neighborhood Hits	90	Target Neighborhood Hits	425	Shared Neighborhood Hits	12
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB5_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.070503 (rank : 67)
Query Neighborhood Hits	90	Target Neighborhood Hits	395	Shared Neighborhood Hits	10
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

DDEF2_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.053901 (rank : 76)
Query Neighborhood Hits	90	Target Neighborhood Hits	599	Shared Neighborhood Hits	14
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.052664 (rank : 80)
Query Neighborhood Hits	90	Target Neighborhood Hits	625	Shared Neighborhood Hits	11
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDFL1_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.052139 (rank : 82)
Query Neighborhood Hits	90	Target Neighborhood Hits	353	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

FA13A_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.065528 (rank : 72)
Query Neighborhood Hits	90	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

FA13A_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.066038 (rank : 71)
Query Neighborhood Hits	90	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

FA13C_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.051033 (rank : 86)
Query Neighborhood Hits	90	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

GRP3_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.068744 (rank : 69)
Query Neighborhood Hits	90	Target Neighborhood Hits	131	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

MYO10_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.052015 (rank : 84)
Query Neighborhood Hits	90	Target Neighborhood Hits	920	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

OCRL_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.272443 (rank : 62)
Query Neighborhood Hits	90	Target Neighborhood Hits	77	Shared Neighborhood Hits	49
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

P85A_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.306913 (rank : 60)
Query Neighborhood Hits	90	Target Neighborhood Hits	435	Shared Neighborhood Hits	58
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85B_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.073961 (rank : 66)
Query Neighborhood Hits	90	Target Neighborhood Hits	543	Shared Neighborhood Hits	29
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PCTL_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.093774 (rank : 64)
Query Neighborhood Hits	90	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

PCTL_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.094861 (rank : 63)
Query Neighborhood Hits	90	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

PKHA1_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.053131 (rank : 79)
Query Neighborhood Hits	90	Target Neighborhood Hits	127	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

SMAP1_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.052559 (rank : 81)
Query Neighborhood Hits	90	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMAP1_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.052022 (rank : 83)
Query Neighborhood Hits	90	Target Neighborhood Hits	120	Shared Neighborhood Hits	5
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMP1L_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.053941 (rank : 74)
Query Neighborhood Hits	90	Target Neighborhood Hits	74	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.053908 (rank : 75)
Query Neighborhood Hits	90	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

Hits sorted by NC score

RHG18_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	90	Target Neighborhood Hits	90	Shared Neighborhood Hits	90
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

RHG18_MOUSE
NC score	0.987326 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	90	Target Neighborhood Hits	110	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG09_HUMAN
NC score	0.779803 (rank : 3)	θ value	2.28291e-11 (rank : 28)
Query Neighborhood Hits	90	Target Neighborhood Hits	186	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

RHG06_HUMAN
NC score	0.778129 (rank : 4)	θ value	7.09661e-13 (rank : 17)
Query Neighborhood Hits	90	Target Neighborhood Hits	114	Shared Neighborhood Hits	61
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG06_MOUSE
NC score	0.776791 (rank : 5)	θ value	2.69671e-12 (rank : 22)
Query Neighborhood Hits	90	Target Neighborhood Hits	105	Shared Neighborhood Hits	60
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG12_HUMAN
NC score	0.771914 (rank : 6)	θ value	1.80466e-16 (rank : 9)
Query Neighborhood Hits	90	Target Neighborhood Hits	190	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_MOUSE
NC score	0.767706 (rank : 7)	θ value	1.38178e-16 (rank : 8)
Query Neighborhood Hits	90	Target Neighborhood Hits	204	Shared Neighborhood Hits	60
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

3BP1_MOUSE
NC score	0.767309 (rank : 8)	θ value	5.08577e-11 (rank : 30)
Query Neighborhood Hits	90	Target Neighborhood Hits	238	Shared Neighborhood Hits	60
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

GMIP_MOUSE
NC score	0.765847 (rank : 9)	θ value	4.16044e-13 (rank : 16)
Query Neighborhood Hits	90	Target Neighborhood Hits	202	Shared Neighborhood Hits	61
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GMIP_HUMAN
NC score	0.763814 (rank : 10)	θ value	1.86753e-13 (rank : 15)
Query Neighborhood Hits	90	Target Neighborhood Hits	225	Shared Neighborhood Hits	61
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RGAP1_HUMAN
NC score	0.762627 (rank : 11)	θ value	9.26847e-13 (rank : 18)
Query Neighborhood Hits	90	Target Neighborhood Hits	189	Shared Neighborhood Hits	61
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG07_MOUSE
NC score	0.758744 (rank : 12)	θ value	1.09232e-21 (rank : 3)
Query Neighborhood Hits	90	Target Neighborhood Hits	103	Shared Neighborhood Hits	60
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG07_HUMAN
NC score	0.753927 (rank : 13)	θ value	9.24701e-21 (rank : 4)
Query Neighborhood Hits	90	Target Neighborhood Hits	108	Shared Neighborhood Hits	60
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

3BP1_HUMAN
NC score	0.753504 (rank : 14)	θ value	6.41864e-14 (rank : 13)
Query Neighborhood Hits	90	Target Neighborhood Hits	376	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RGAP1_MOUSE
NC score	0.750594 (rank : 15)	θ value	4.30538e-10 (rank : 43)
Query Neighborhood Hits	90	Target Neighborhood Hits	185	Shared Neighborhood Hits	61
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG01_HUMAN
NC score	0.744148 (rank : 16)	θ value	2.28291e-11 (rank : 27)
Query Neighborhood Hits	90	Target Neighborhood Hits	75	Shared Neighborhood Hits	60
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

GRLF1_HUMAN
NC score	0.729330 (rank : 17)	θ value	1.133e-10 (rank : 33)
Query Neighborhood Hits	90	Target Neighborhood Hits	167	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

RHG08_MOUSE
NC score	0.724505 (rank : 18)	θ value	1.47974e-10 (rank : 39)
Query Neighborhood Hits	90	Target Neighborhood Hits	73	Shared Neighborhood Hits	60
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RBP1_MOUSE
NC score	0.724453 (rank : 19)	θ value	1.38178e-16 (rank : 7)
Query Neighborhood Hits	90	Target Neighborhood Hits	493	Shared Neighborhood Hits	70
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

STA13_HUMAN
NC score	0.715308 (rank : 20)	θ value	8.95645e-16 (rank : 11)
Query Neighborhood Hits	90	Target Neighborhood Hits	89	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

CHIO_MOUSE
NC score	0.714100 (rank : 21)	θ value	3.52202e-12 (rank : 23)
Query Neighborhood Hits	90	Target Neighborhood Hits	130	Shared Neighborhood Hits	59
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

RHG08_HUMAN
NC score	0.714054 (rank : 22)	θ value	1.63604e-09 (rank : 44)
Query Neighborhood Hits	90	Target Neighborhood Hits	88	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

TCGAP_MOUSE
NC score	0.710218 (rank : 23)	θ value	1.133e-10 (rank : 37)
Query Neighborhood Hits	90	Target Neighborhood Hits	409	Shared Neighborhood Hits	60
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

OPHN1_MOUSE
NC score	0.709029 (rank : 24)	θ value	1.133e-10 (rank : 35)
Query Neighborhood Hits	90	Target Neighborhood Hits	174	Shared Neighborhood Hits	60
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

OPHN1_HUMAN
NC score	0.708284 (rank : 25)	θ value	1.9326e-10 (rank : 41)
Query Neighborhood Hits	90	Target Neighborhood Hits	161	Shared Neighborhood Hits	60
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

STAR8_MOUSE
NC score	0.706411 (rank : 26)	θ value	3.52202e-12 (rank : 24)
Query Neighborhood Hits	90	Target Neighborhood Hits	101	Shared Neighborhood Hits	58
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STA13_MOUSE
NC score	0.704890 (rank : 27)	θ value	6.41864e-14 (rank : 14)
Query Neighborhood Hits	90	Target Neighborhood Hits	89	Shared Neighborhood Hits	58
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

RBP1_HUMAN
NC score	0.704603 (rank : 28)	θ value	3.07829e-16 (rank : 10)
Query Neighborhood Hits	90	Target Neighborhood Hits	521	Shared Neighborhood Hits	70
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

STAR8_HUMAN
NC score	0.697666 (rank : 29)	θ value	2.0648e-12 (rank : 20)
Query Neighborhood Hits	90	Target Neighborhood Hits	216	Shared Neighborhood Hits	58
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

ABR_HUMAN
NC score	0.693869 (rank : 30)	θ value	2.60593e-15 (rank : 12)
Query Neighborhood Hits	90	Target Neighborhood Hits	166	Shared Neighborhood Hits	60
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

RHG05_MOUSE
NC score	0.686918 (rank : 31)	θ value	8.11959e-09 (rank : 47)
Query Neighborhood Hits	90	Target Neighborhood Hits	165	Shared Neighborhood Hits	64
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG25_MOUSE
NC score	0.682555 (rank : 32)	θ value	1.9326e-10 (rank : 42)
Query Neighborhood Hits	90	Target Neighborhood Hits	492	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG26_HUMAN
NC score	0.682144 (rank : 33)	θ value	9.26847e-13 (rank : 19)
Query Neighborhood Hits	90	Target Neighborhood Hits	281	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

CHIN_HUMAN
NC score	0.681554 (rank : 34)	θ value	2.98157e-11 (rank : 29)
Query Neighborhood Hits	90	Target Neighborhood Hits	227	Shared Neighborhood Hits	59
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIO_HUMAN
NC score	0.680908 (rank : 35)	θ value	7.84624e-12 (rank : 26)
Query Neighborhood Hits	90	Target Neighborhood Hits	220	Shared Neighborhood Hits	59
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHIN_MOUSE
NC score	0.680289 (rank : 36)	θ value	1.133e-10 (rank : 32)
Query Neighborhood Hits	90	Target Neighborhood Hits	229	Shared Neighborhood Hits	60
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

RHG05_HUMAN
NC score	0.674161 (rank : 37)	θ value	4.0297e-08 (rank : 50)
Query Neighborhood Hits	90	Target Neighborhood Hits	158	Shared Neighborhood Hits	63
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

BCR_HUMAN
NC score	0.671531 (rank : 38)	θ value	6.21693e-09 (rank : 45)
Query Neighborhood Hits	90	Target Neighborhood Hits	204	Shared Neighborhood Hits	60
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

RHG25_HUMAN
NC score	0.663949 (rank : 39)	θ value	8.67504e-11 (rank : 31)
Query Neighborhood Hits	90	Target Neighborhood Hits	550	Shared Neighborhood Hits	66
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

TAGAP_MOUSE
NC score	0.656129 (rank : 40)	θ value	9.29e-05 (rank : 57)
Query Neighborhood Hits	90	Target Neighborhood Hits	83	Shared Neighborhood Hits	58
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

TAGAP_HUMAN
NC score	0.651433 (rank : 41)	θ value	0.000786445 (rank : 58)
Query Neighborhood Hits	90	Target Neighborhood Hits	82	Shared Neighborhood Hits	57
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

RHG04_HUMAN
NC score	0.651206 (rank : 42)	θ value	4.0297e-08 (rank : 49)
Query Neighborhood Hits	90	Target Neighborhood Hits	307	Shared Neighborhood Hits	62
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

SRGP2_HUMAN
NC score	0.632943 (rank : 43)	θ value	4.0297e-08 (rank : 51)
Query Neighborhood Hits	90	Target Neighborhood Hits	331	Shared Neighborhood Hits	61
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

TCGAP_HUMAN
NC score	0.630850 (rank : 44)	θ value	1.133e-10 (rank : 36)
Query Neighborhood Hits	90	Target Neighborhood Hits	872	Shared Neighborhood Hits	63
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

SRGP2_MOUSE
NC score	0.623985 (rank : 45)	θ value	8.97725e-08 (rank : 52)
Query Neighborhood Hits	90	Target Neighborhood Hits	324	Shared Neighborhood Hits	62
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

CE005_HUMAN
NC score	0.620193 (rank : 46)	θ value	1.06045e-08 (rank : 48)
Query Neighborhood Hits	90	Target Neighborhood Hits	213	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

CE005_MOUSE
NC score	0.618616 (rank : 47)	θ value	6.21693e-09 (rank : 46)
Query Neighborhood Hits	90	Target Neighborhood Hits	238	Shared Neighborhood Hits	65
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

FNBP2_HUMAN
NC score	0.615601 (rank : 48)	θ value	1.99992e-07 (rank : 53)
Query Neighborhood Hits	90	Target Neighborhood Hits	432	Shared Neighborhood Hits	65
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

SRGP1_HUMAN
NC score	0.610653 (rank : 49)	θ value	3.77169e-06 (rank : 56)
Query Neighborhood Hits	90	Target Neighborhood Hits	390	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

CEND2_HUMAN
NC score	0.604772 (rank : 50)	θ value	1.9326e-10 (rank : 40)
Query Neighborhood Hits	90	Target Neighborhood Hits	166	Shared Neighborhood Hits	58
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

K1688_MOUSE
NC score	0.593796 (rank : 51)	θ value	1.133e-10 (rank : 34)
Query Neighborhood Hits	90	Target Neighborhood Hits	188	Shared Neighborhood Hits	57
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

CEND3_MOUSE
NC score	0.586559 (rank : 52)	θ value	4.59992e-12 (rank : 25)
Query Neighborhood Hits	90	Target Neighborhood Hits	228	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

K1688_HUMAN
NC score	0.580052 (rank : 53)	θ value	1.47974e-10 (rank : 38)
Query Neighborhood Hits	90	Target Neighborhood Hits	217	Shared Neighborhood Hits	58
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

CEND3_HUMAN
NC score	0.578270 (rank : 54)	θ value	2.69671e-12 (rank : 21)
Query Neighborhood Hits	90	Target Neighborhood Hits	275	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CEND1_MOUSE
NC score	0.506620 (rank : 55)	θ value	3.41135e-07 (rank : 54)
Query Neighborhood Hits	90	Target Neighborhood Hits	260	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CEND1_HUMAN
NC score	0.486114 (rank : 56)	θ value	9.92553e-07 (rank : 55)
Query Neighborhood Hits	90	Target Neighborhood Hits	284	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

MYO9B_MOUSE
NC score	0.413054 (rank : 57)	θ value	1.38178e-16 (rank : 6)
Query Neighborhood Hits	90	Target Neighborhood Hits	311	Shared Neighborhood Hits	62
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_HUMAN
NC score	0.407466 (rank : 58)	θ value	8.10077e-17 (rank : 5)
Query Neighborhood Hits	90	Target Neighborhood Hits	641	Shared Neighborhood Hits	61
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

P85A_HUMAN
NC score	0.319128 (rank : 59)	θ value	0.00102713 (rank : 59)
Query Neighborhood Hits	90	Target Neighborhood Hits	479	Shared Neighborhood Hits	59
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_MOUSE
NC score	0.306913 (rank : 60)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	90	Target Neighborhood Hits	435	Shared Neighborhood Hits	58
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

I5P2_HUMAN
NC score	0.305335 (rank : 61)	θ value	0.00390308 (rank : 60)
Query Neighborhood Hits	90	Target Neighborhood Hits	86	Shared Neighborhood Hits	50
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

OCRL_HUMAN
NC score	0.272443 (rank : 62)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	90	Target Neighborhood Hits	77	Shared Neighborhood Hits	49
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

PCTL_MOUSE
NC score	0.094861 (rank : 63)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	90	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

PCTL_HUMAN
NC score	0.093774 (rank : 64)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	90	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

CENB2_HUMAN
NC score	0.076308 (rank : 65)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	90	Target Neighborhood Hits	425	Shared Neighborhood Hits	12
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

P85B_HUMAN
NC score	0.073961 (rank : 66)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	90	Target Neighborhood Hits	543	Shared Neighborhood Hits	29
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

CENB5_HUMAN
NC score	0.070503 (rank : 67)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	90	Target Neighborhood Hits	395	Shared Neighborhood Hits	10
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CENB1_HUMAN
NC score	0.070211 (rank : 68)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	90	Target Neighborhood Hits	383	Shared Neighborhood Hits	11
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

GRP3_HUMAN
NC score	0.068744 (rank : 69)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	90	Target Neighborhood Hits	131	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

FACD2_HUMAN
NC score	0.066352 (rank : 70)	θ value	0.0330416 (rank : 61)
Query Neighborhood Hits	90	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BXW9, Q2LA86, Q69YP9, Q6PJN7, Q9BQ06, Q9H9T9	Gene names	FANCD2
Domain Architecture	No domain graphic available
Description	Fanconi anemia group D2 protein (Protein FACD2).

FA13A_MOUSE
NC score	0.066038 (rank : 71)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	90	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

FA13A_HUMAN
NC score	0.065528 (rank : 72)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	90	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

CENA2_HUMAN
NC score	0.054774 (rank : 73)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	90	Target Neighborhood Hits	83	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

SMP1L_HUMAN
NC score	0.053941 (rank : 74)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	90	Target Neighborhood Hits	74	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
NC score	0.053908 (rank : 75)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	90	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

DDEF2_HUMAN
NC score	0.053901 (rank : 76)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	90	Target Neighborhood Hits	599	Shared Neighborhood Hits	14
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

BNIP2_HUMAN
NC score	0.053614 (rank : 77)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	90	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q12982	Gene names	BNIP2, NIP2
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

BNIP2_MOUSE
NC score	0.053528 (rank : 78)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	90	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	O54940	Gene names	Bnip2, Nip2l
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

PKHA1_HUMAN
NC score	0.053131 (rank : 79)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	90	Target Neighborhood Hits	127	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

DDEF2_MOUSE
NC score	0.052664 (rank : 80)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	90	Target Neighborhood Hits	625	Shared Neighborhood Hits	11
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

SMAP1_HUMAN
NC score	0.052559 (rank : 81)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	90	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

DDFL1_HUMAN
NC score	0.052139 (rank : 82)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	90	Target Neighborhood Hits	353	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

SMAP1_MOUSE
NC score	0.052022 (rank : 83)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	90	Target Neighborhood Hits	120	Shared Neighborhood Hits	5
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

MYO10_HUMAN
NC score	0.052015 (rank : 84)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	90	Target Neighborhood Hits	920	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

CENA1_HUMAN
NC score	0.051319 (rank : 85)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	90	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

FA13C_HUMAN
NC score	0.051033 (rank : 86)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	90	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

ATCAY_MOUSE
NC score	0.050965 (rank : 87)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	90	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHE3, Q3TR94	Gene names	Atcay
Domain Architecture
Description	Caytaxin.

ATCAY_HUMAN
NC score	0.050505 (rank : 88)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	90	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q86WG3, Q8NAQ2, Q8TAQ3, Q96HC6, Q96JF5	Gene names	ATCAY, KIAA1872
Domain Architecture
Description	Caytaxin (Ataxia Cayman type protein) (BNIP-H).

DBLOH_MOUSE
NC score	0.030717 (rank : 89)	θ value	1.81305 (rank : 68)
Query Neighborhood Hits	90	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIQ3, Q9CZD1, Q9DCD3	Gene names	Diablo, Smac
Domain Architecture	No domain graphic available
Description	Diablo homolog, mitochondrial precursor (Second mitochondria-derived activator of caspase) (Smac protein) (Direct IAP-binding protein with low pI).

RABE1_HUMAN
NC score	0.025276 (rank : 90)	θ value	0.0736092 (rank : 62)
Query Neighborhood Hits	90	Target Neighborhood Hits	1104	Shared Neighborhood Hits	20
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

DBLOH_HUMAN
NC score	0.023731 (rank : 91)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	90	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR28, Q96LV0, Q9BT11, Q9HAV6	Gene names	DIABLO, SMAC
Domain Architecture	No domain graphic available
Description	Diablo homolog, mitochondrial precursor (Second mitochondria-derived activator of caspase) (Smac protein) (Direct IAP-binding protein with low pI).

5NT1B_MOUSE
NC score	0.022472 (rank : 92)	θ value	1.06291 (rank : 65)
Query Neighborhood Hits	90	Target Neighborhood Hits	78	Shared Neighborhood Hits	2
SwissProt Accessions	Q91YE9, Q91Y48	Gene names	Nt5c1b, Airp
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

NIN_HUMAN
NC score	0.022103 (rank : 93)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	90	Target Neighborhood Hits	1416	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

RABE1_MOUSE
NC score	0.019800 (rank : 94)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	90	Target Neighborhood Hits	1105	Shared Neighborhood Hits	20
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

MCM4_MOUSE
NC score	0.018984 (rank : 95)	θ value	1.81305 (rank : 71)
Query Neighborhood Hits	90	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	P49717, O89056	Gene names	Mcm4, Cdc21, Mcmd4
Domain Architecture
Description	DNA replication licensing factor MCM4 (CDC21 homolog) (P1-CDC21).

IF4G1_HUMAN
NC score	0.017646 (rank : 96)	θ value	1.06291 (rank : 67)
Query Neighborhood Hits	90	Target Neighborhood Hits	347	Shared Neighborhood Hits	5
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

FLIP1_HUMAN
NC score	0.016137 (rank : 97)	θ value	0.365318 (rank : 64)
Query Neighborhood Hits	90	Target Neighborhood Hits	1405	Shared Neighborhood Hits	18
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GOGA4_MOUSE
NC score	0.014202 (rank : 98)	θ value	1.81305 (rank : 69)
Query Neighborhood Hits	90	Target Neighborhood Hits	1939	Shared Neighborhood Hits	22
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

RAE2_HUMAN
NC score	0.013703 (rank : 99)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	90	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P26374, Q9H1Y4	Gene names	CHML, REP2
Domain Architecture
Description	Rab proteins geranylgeranyltransferase component A 2 (Rab escort protein 2) (REP-2) (Choroideraemia-like protein).

MCM4_HUMAN
NC score	0.013549 (rank : 100)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	90	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	P33991, Q8NEH1, Q99658	Gene names	MCM4, CDC21
Domain Architecture
Description	DNA replication licensing factor MCM4 (CDC21 homolog) (P1-CDC21).

GOGA5_MOUSE
NC score	0.013522 (rank : 101)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	90	Target Neighborhood Hits	1434	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

TRIPB_HUMAN
NC score	0.012616 (rank : 102)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	90	Target Neighborhood Hits	1587	Shared Neighborhood Hits	22
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

COG8_MOUSE
NC score	0.011591 (rank : 103)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	90	Target Neighborhood Hits	147	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JJA2	Gene names	Cog8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

KPBB_MOUSE
NC score	0.010172 (rank : 104)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	90	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TSH2	Gene names	Phkb
Domain Architecture	No domain graphic available
Description	Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta).

RBL1_MOUSE
NC score	0.008603 (rank : 105)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	90	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q64701	Gene names	Rbl1
Domain Architecture
Description	Retinoblastoma-like protein 1 (107 kDa retinoblastoma-associated protein) (PRB1) (P107).

SMCA4_HUMAN
NC score	0.008484 (rank : 106)	θ value	1.81305 (rank : 72)
Query Neighborhood Hits	90	Target Neighborhood Hits	597	Shared Neighborhood Hits	9
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

PAR14_MOUSE
NC score	0.008333 (rank : 107)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	90	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

KI21B_HUMAN
NC score	0.007173 (rank : 108)	θ value	1.81305 (rank : 70)
Query Neighborhood Hits	90	Target Neighborhood Hits	1017	Shared Neighborhood Hits	15
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

SMRCD_MOUSE
NC score	0.006536 (rank : 109)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	90	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

KI21B_MOUSE
NC score	0.006229 (rank : 110)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	90	Target Neighborhood Hits	997	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

ROCK1_HUMAN
NC score	0.006144 (rank : 111)	θ value	0.279714 (rank : 63)
Query Neighborhood Hits	90	Target Neighborhood Hits	2000	Shared Neighborhood Hits	21
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

RPGF6_HUMAN
NC score	0.005874 (rank : 112)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	90	Target Neighborhood Hits	266	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

PRAX_HUMAN
NC score	0.004814 (rank : 113)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	90	Target Neighborhood Hits	215	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

KLHL6_MOUSE
NC score	0.001420 (rank : 114)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	90	Target Neighborhood Hits	186	Shared Neighborhood Hits	3
SwissProt Accessions	Q6V595	Gene names	Klhl6
Domain Architecture	No domain graphic available
Description	Kelch-like protein 6.

ITB2_HUMAN
NC score	0.001116 (rank : 115)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	90	Target Neighborhood Hits	282	Shared Neighborhood Hits	2
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

WNK4_HUMAN
NC score	-0.002275 (rank : 116)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	90	Target Neighborhood Hits	1043	Shared Neighborhood Hits	7
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

DAPK3_HUMAN
NC score	-0.002577 (rank : 117)	θ value	1.06291 (rank : 66)
Query Neighborhood Hits	90	Target Neighborhood Hits	945	Shared Neighborhood Hits	5
SwissProt Accessions	O43293	Gene names	DAPK3, ZIPK
Domain Architecture
Description	Death-associated protein kinase 3 (EC 2.7.11.1) (DAP kinase 3) (DAP- like kinase) (Dlk) (ZIP-kinase).