Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : SMP1L_MOUSE

For an explanation of this page, click here

SMP1L_MOUSE
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SMP1L_HUMAN
θ value	0 (rank : 1)	NC score	0.995531 (rank : 2)
Query Neighborhood Hits	70	Target Neighborhood Hits	74	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	70	Target Neighborhood Hits	70	Shared Neighborhood Hits	70
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SMAP1_MOUSE
θ value	9.056e-93 (rank : 3)	NC score	0.969184 (rank : 4)
Query Neighborhood Hits	70	Target Neighborhood Hits	120	Shared Neighborhood Hits	41
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMAP1_HUMAN
θ value	8.77142e-88 (rank : 4)	NC score	0.971511 (rank : 3)
Query Neighborhood Hits	70	Target Neighborhood Hits	98	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

CENB5_HUMAN
θ value	3.17815e-21 (rank : 5)	NC score	0.622421 (rank : 24)
Query Neighborhood Hits	70	Target Neighborhood Hits	395	Shared Neighborhood Hits	40
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CENB2_HUMAN
θ value	9.24701e-21 (rank : 6)	NC score	0.611909 (rank : 25)
Query Neighborhood Hits	70	Target Neighborhood Hits	425	Shared Neighborhood Hits	41
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB1_HUMAN
θ value	2.06002e-20 (rank : 7)	NC score	0.630907 (rank : 21)
Query Neighborhood Hits	70	Target Neighborhood Hits	383	Shared Neighborhood Hits	40
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENG2_HUMAN
θ value	3.51386e-20 (rank : 8)	NC score	0.629024 (rank : 23)
Query Neighborhood Hits	70	Target Neighborhood Hits	471	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CENA2_HUMAN
θ value	7.82807e-20 (rank : 9)	NC score	0.800358 (rank : 7)
Query Neighborhood Hits	70	Target Neighborhood Hits	83	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CENG2_MOUSE
θ value	1.02238e-19 (rank : 10)	NC score	0.631872 (rank : 20)
Query Neighborhood Hits	70	Target Neighborhood Hits	463	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

CENG3_HUMAN
θ value	1.74391e-19 (rank : 11)	NC score	0.653730 (rank : 14)
Query Neighborhood Hits	70	Target Neighborhood Hits	455	Shared Neighborhood Hits	38
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
θ value	2.97466e-19 (rank : 12)	NC score	0.653011 (rank : 15)
Query Neighborhood Hits	70	Target Neighborhood Hits	467	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENA1_HUMAN
θ value	6.62687e-19 (rank : 13)	NC score	0.825933 (rank : 5)
Query Neighborhood Hits	70	Target Neighborhood Hits	87	Shared Neighborhood Hits	38
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CENA2_MOUSE
θ value	4.29542e-18 (rank : 14)	NC score	0.804245 (rank : 6)
Query Neighborhood Hits	70	Target Neighborhood Hits	68	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

CENG1_HUMAN
θ value	5.60996e-18 (rank : 15)	NC score	0.649747 (rank : 16)
Query Neighborhood Hits	70	Target Neighborhood Hits	544	Shared Neighborhood Hits	41
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG1_MOUSE
θ value	9.56915e-18 (rank : 16)	NC score	0.656702 (rank : 13)
Query Neighborhood Hits	70	Target Neighborhood Hits	531	Shared Neighborhood Hits	40
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

DDEF1_MOUSE
θ value	1.63225e-17 (rank : 17)	NC score	0.635607 (rank : 18)
Query Neighborhood Hits	70	Target Neighborhood Hits	592	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

CEND2_HUMAN
θ value	1.16975e-15 (rank : 18)	NC score	0.573498 (rank : 32)
Query Neighborhood Hits	70	Target Neighborhood Hits	166	Shared Neighborhood Hits	38
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

ARFG3_MOUSE
θ value	3.40345e-15 (rank : 19)	NC score	0.774979 (rank : 10)
Query Neighborhood Hits	70	Target Neighborhood Hits	80	Shared Neighborhood Hits	38
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ARFG3_HUMAN
θ value	7.58209e-15 (rank : 20)	NC score	0.779946 (rank : 9)
Query Neighborhood Hits	70	Target Neighborhood Hits	56	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

DDEF2_MOUSE
θ value	2.88119e-14 (rank : 21)	NC score	0.604981 (rank : 27)
Query Neighborhood Hits	70	Target Neighborhood Hits	625	Shared Neighborhood Hits	40
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

CEND3_HUMAN
θ value	4.91457e-14 (rank : 22)	NC score	0.565810 (rank : 33)
Query Neighborhood Hits	70	Target Neighborhood Hits	275	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

ARFG1_MOUSE
θ value	8.38298e-14 (rank : 23)	NC score	0.786040 (rank : 8)
Query Neighborhood Hits	70	Target Neighborhood Hits	51	Shared Neighborhood Hits	38
SwissProt Accessions	Q9EPJ9, Q3TI52, Q8BMM6, Q8BMQ7	Gene names	Arfgap1, Arf1gap
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

DDEF2_HUMAN
θ value	8.38298e-14 (rank : 24)	NC score	0.608990 (rank : 26)
Query Neighborhood Hits	70	Target Neighborhood Hits	599	Shared Neighborhood Hits	41
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

ARFG1_HUMAN
θ value	1.09485e-13 (rank : 25)	NC score	0.770003 (rank : 11)
Query Neighborhood Hits	70	Target Neighborhood Hits	60	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N6T3, Q96KC4, Q96T02, Q9NSU3, Q9NVF6, Q9UIL0	Gene names	ARFGAP1, ARF1GAP
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

DDFL1_MOUSE
θ value	1.09485e-13 (rank : 26)	NC score	0.629453 (rank : 22)
Query Neighborhood Hits	70	Target Neighborhood Hits	324	Shared Neighborhood Hits	39
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

CEND1_MOUSE
θ value	2.43908e-13 (rank : 27)	NC score	0.586895 (rank : 28)
Query Neighborhood Hits	70	Target Neighborhood Hits	260	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CEND3_MOUSE
θ value	3.18553e-13 (rank : 28)	NC score	0.563112 (rank : 35)
Query Neighborhood Hits	70	Target Neighborhood Hits	228	Shared Neighborhood Hits	41
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CEND1_HUMAN
θ value	4.16044e-13 (rank : 29)	NC score	0.586273 (rank : 29)
Query Neighborhood Hits	70	Target Neighborhood Hits	284	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

DDFL1_HUMAN
θ value	7.09661e-13 (rank : 30)	NC score	0.660187 (rank : 12)
Query Neighborhood Hits	70	Target Neighborhood Hits	353	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

GIT2_MOUSE
θ value	1.02475e-11 (rank : 31)	NC score	0.577279 (rank : 31)
Query Neighborhood Hits	70	Target Neighborhood Hits	323	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

GIT2_HUMAN
θ value	1.33837e-11 (rank : 32)	NC score	0.578260 (rank : 30)
Query Neighborhood Hits	70	Target Neighborhood Hits	381	Shared Neighborhood Hits	40
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

NUPL_HUMAN
θ value	3.89403e-11 (rank : 33)	NC score	0.640016 (rank : 17)
Query Neighborhood Hits	70	Target Neighborhood Hits	68	Shared Neighborhood Hits	36
SwissProt Accessions	P52594, Q15277, Q4VAS0, Q4VAS1, Q4VAS3, Q53QT8, Q53R11	Gene names	HRB, RAB, RIP
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein) (Rev- interacting protein) (Rev/Rex activation domain-binding protein).

NUPL_MOUSE
θ value	3.89403e-11 (rank : 34)	NC score	0.634698 (rank : 19)
Query Neighborhood Hits	70	Target Neighborhood Hits	113	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K2K6, O70448, Q8BQL5, Q8CDK9	Gene names	Hrb, Rip
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein homolog).

GIT1_HUMAN
θ value	2.52405e-10 (rank : 35)	NC score	0.557696 (rank : 36)
Query Neighborhood Hits	70	Target Neighborhood Hits	336	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GIT1_MOUSE
θ value	2.52405e-10 (rank : 36)	NC score	0.556524 (rank : 37)
Query Neighborhood Hits	70	Target Neighborhood Hits	341	Shared Neighborhood Hits	35
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

HRBL_HUMAN
θ value	6.21693e-09 (rank : 37)	NC score	0.564652 (rank : 34)
Query Neighborhood Hits	70	Target Neighborhood Hits	179	Shared Neighborhood Hits	41
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

HRBL_MOUSE
θ value	8.97725e-08 (rank : 38)	NC score	0.533884 (rank : 38)
Query Neighborhood Hits	70	Target Neighborhood Hits	269	Shared Neighborhood Hits	39
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

NSD1_HUMAN
θ value	0.00175202 (rank : 39)	NC score	0.041586 (rank : 185)
Query Neighborhood Hits	70	Target Neighborhood Hits	427	Shared Neighborhood Hits	8
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

DAB1_HUMAN
θ value	0.0431538 (rank : 40)	NC score	0.036310 (rank : 187)
Query Neighborhood Hits	70	Target Neighborhood Hits	219	Shared Neighborhood Hits	7
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

BCL9_MOUSE
θ value	0.163984 (rank : 41)	NC score	0.057975 (rank : 112)
Query Neighborhood Hits	70	Target Neighborhood Hits	770	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

JHD3D_HUMAN
θ value	0.21417 (rank : 42)	NC score	0.018496 (rank : 192)
Query Neighborhood Hits	70	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	Q6B0I6, Q9NT41, Q9NW76	Gene names	JMJD2D, JHDM3D
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

NCOA6_HUMAN
θ value	0.21417 (rank : 43)	NC score	0.057666 (rank : 115)
Query Neighborhood Hits	70	Target Neighborhood Hits	1202	Shared Neighborhood Hits	18
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

BCL9_HUMAN
θ value	0.279714 (rank : 44)	NC score	0.047868 (rank : 183)
Query Neighborhood Hits	70	Target Neighborhood Hits	1008	Shared Neighborhood Hits	14
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

FOSL1_HUMAN
θ value	0.62314 (rank : 45)	NC score	0.035883 (rank : 188)
Query Neighborhood Hits	70	Target Neighborhood Hits	112	Shared Neighborhood Hits	4
SwissProt Accessions	P15407	Gene names	FOSL1, FRA1
Domain Architecture
Description	Fos-related antigen 1 (FRA-1).

NFH_HUMAN
θ value	1.06291 (rank : 46)	NC score	0.002551 (rank : 207)
Query Neighborhood Hits	70	Target Neighborhood Hits	1242	Shared Neighborhood Hits	8
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SYNG_MOUSE
θ value	1.06291 (rank : 47)	NC score	0.038194 (rank : 186)
Query Neighborhood Hits	70	Target Neighborhood Hits	206	Shared Neighborhood Hits	10
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

EPN2_HUMAN
θ value	1.38821 (rank : 48)	NC score	0.025964 (rank : 190)
Query Neighborhood Hits	70	Target Neighborhood Hits	156	Shared Neighborhood Hits	10
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

NCOA6_MOUSE
θ value	1.38821 (rank : 49)	NC score	0.061192 (rank : 92)
Query Neighborhood Hits	70	Target Neighborhood Hits	1076	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

ANR25_HUMAN
θ value	1.81305 (rank : 50)	NC score	0.044784 (rank : 184)
Query Neighborhood Hits	70	Target Neighborhood Hits	350	Shared Neighborhood Hits	15
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

TLE1_HUMAN
θ value	2.36792 (rank : 51)	NC score	0.008737 (rank : 199)
Query Neighborhood Hits	70	Target Neighborhood Hits	485	Shared Neighborhood Hits	8
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

HGD_HUMAN
θ value	3.0926 (rank : 52)	NC score	0.026175 (rank : 189)
Query Neighborhood Hits	70	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q93099	Gene names	HGD, HGO
Domain Architecture
Description	Homogentisate 1,2-dioxygenase (EC 1.13.11.5) (Homogentisicase) (Homogentisate oxygenase) (Homogentisic acid oxidase).

KTN1_MOUSE
θ value	3.0926 (rank : 53)	NC score	0.002058 (rank : 209)
Query Neighborhood Hits	70	Target Neighborhood Hits	1324	Shared Neighborhood Hits	12
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

PININ_HUMAN
θ value	3.0926 (rank : 54)	NC score	0.013568 (rank : 195)
Query Neighborhood Hits	70	Target Neighborhood Hits	753	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

SDCG8_MOUSE
θ value	3.0926 (rank : 55)	NC score	0.008952 (rank : 198)
Query Neighborhood Hits	70	Target Neighborhood Hits	886	Shared Neighborhood Hits	11
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

TLE1_MOUSE
θ value	3.0926 (rank : 56)	NC score	0.007818 (rank : 200)
Query Neighborhood Hits	70	Target Neighborhood Hits	491	Shared Neighborhood Hits	6
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

TRI14_MOUSE
θ value	3.0926 (rank : 57)	NC score	0.009673 (rank : 197)
Query Neighborhood Hits	70	Target Neighborhood Hits	137	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

CBP_MOUSE
θ value	4.03905 (rank : 58)	NC score	0.025275 (rank : 191)
Query Neighborhood Hits	70	Target Neighborhood Hits	1051	Shared Neighborhood Hits	16
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

TBX21_MOUSE
θ value	4.03905 (rank : 59)	NC score	0.006890 (rank : 202)
Query Neighborhood Hits	70	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JKD8, Q9R0A6	Gene names	Tbx21, Tbet, Tblym
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

ADNP_HUMAN
θ value	6.88961 (rank : 60)	NC score	0.011934 (rank : 196)
Query Neighborhood Hits	70	Target Neighborhood Hits	265	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H2P0, O94881, Q9UG34	Gene names	ADNP, KIAA0784
Domain Architecture
Description	Activity-dependent neuroprotector (Activity-dependent neuroprotective protein).

TITIN_HUMAN
θ value	6.88961 (rank : 61)	NC score	-0.002351 (rank : 211)
Query Neighborhood Hits	70	Target Neighborhood Hits	2923	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TRPM7_MOUSE
θ value	6.88961 (rank : 62)	NC score	0.004737 (rank : 203)
Query Neighborhood Hits	70	Target Neighborhood Hits	113	Shared Neighborhood Hits	2
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

ADNP_MOUSE
θ value	8.99809 (rank : 63)	NC score	0.016931 (rank : 193)
Query Neighborhood Hits	70	Target Neighborhood Hits	232	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z103	Gene names	Adnp
Domain Architecture
Description	Activity-dependent neuroprotector (Activity-dependent neuroprotective protein).

CNGA1_MOUSE
θ value	8.99809 (rank : 64)	NC score	0.002422 (rank : 208)
Query Neighborhood Hits	70	Target Neighborhood Hits	198	Shared Neighborhood Hits	3
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

MAGI1_MOUSE
θ value	8.99809 (rank : 65)	NC score	0.001095 (rank : 210)
Query Neighborhood Hits	70	Target Neighborhood Hits	403	Shared Neighborhood Hits	4
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

P73L_MOUSE
θ value	8.99809 (rank : 66)	NC score	0.007353 (rank : 201)
Query Neighborhood Hits	70	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	O88898, O88897, O88899, O89097, Q8C826, Q9QWY9, Q9QWZ0	Gene names	Tp73l, P63, P73l, Trp63
Domain Architecture	No domain graphic available
Description	Tumor protein p73-like (p73L) (p63) (Transformation-related protein 63).

PLCB1_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.004383 (rank : 206)
Query Neighborhood Hits	70	Target Neighborhood Hits	614	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

PLCB1_MOUSE
θ value	8.99809 (rank : 68)	NC score	0.004532 (rank : 204)
Query Neighborhood Hits	70	Target Neighborhood Hits	531	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

TRDN_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.004439 (rank : 205)
Query Neighborhood Hits	70	Target Neighborhood Hits	542	Shared Neighborhood Hits	7
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TTC14_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.013737 (rank : 194)
Query Neighborhood Hits	70	Target Neighborhood Hits	274	Shared Neighborhood Hits	4
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

ACBD6_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.057891 (rank : 113)
Query Neighborhood Hits	70	Target Neighborhood Hits	304	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ACBD6_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.056454 (rank : 125)
Query Neighborhood Hits	70	Target Neighborhood Hits	305	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

AN13B_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.054340 (rank : 149)
Query Neighborhood Hits	70	Target Neighborhood Hits	265	Shared Neighborhood Hits	17
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.054437 (rank : 146)
Query Neighborhood Hits	70	Target Neighborhood Hits	276	Shared Neighborhood Hits	17
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13C_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.051393 (rank : 174)
Query Neighborhood Hits	70	Target Neighborhood Hits	241	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

AN13C_MOUSE
θ value	θ > 10 (rank : 76)	NC score	0.051476 (rank : 173)
Query Neighborhood Hits	70	Target Neighborhood Hits	242	Shared Neighborhood Hits	18
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

AN36A_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.054427 (rank : 147)
Query Neighborhood Hits	70	Target Neighborhood Hits	271	Shared Neighborhood Hits	17
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ANK1_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.061772 (rank : 87)
Query Neighborhood Hits	70	Target Neighborhood Hits	416	Shared Neighborhood Hits	19
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK1_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.061611 (rank : 89)
Query Neighborhood Hits	70	Target Neighborhood Hits	430	Shared Neighborhood Hits	19
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANK2_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.053669 (rank : 157)
Query Neighborhood Hits	70	Target Neighborhood Hits	1615	Shared Neighborhood Hits	31
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANK3_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.053458 (rank : 159)
Query Neighborhood Hits	70	Target Neighborhood Hits	853	Shared Neighborhood Hits	29
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANKR1_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.060504 (rank : 97)
Query Neighborhood Hits	70	Target Neighborhood Hits	308	Shared Neighborhood Hits	20
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ANKR1_MOUSE
θ value	θ > 10 (rank : 83)	NC score	0.061609 (rank : 90)
Query Neighborhood Hits	70	Target Neighborhood Hits	316	Shared Neighborhood Hits	19
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ANKR2_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.065740 (rank : 71)
Query Neighborhood Hits	70	Target Neighborhood Hits	321	Shared Neighborhood Hits	19
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ANKR2_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.060370 (rank : 98)
Query Neighborhood Hits	70	Target Neighborhood Hits	312	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANKR5_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.056311 (rank : 127)
Query Neighborhood Hits	70	Target Neighborhood Hits	297	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANKR5_MOUSE
θ value	θ > 10 (rank : 87)	NC score	0.056137 (rank : 129)
Query Neighborhood Hits	70	Target Neighborhood Hits	298	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANKR6_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.064589 (rank : 74)
Query Neighborhood Hits	70	Target Neighborhood Hits	439	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ANKS3_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.052392 (rank : 165)
Query Neighborhood Hits	70	Target Neighborhood Hits	355	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ANR10_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.064738 (rank : 73)
Query Neighborhood Hits	70	Target Neighborhood Hits	289	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANR10_MOUSE
θ value	θ > 10 (rank : 91)	NC score	0.061804 (rank : 86)
Query Neighborhood Hits	70	Target Neighborhood Hits	273	Shared Neighborhood Hits	18
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANR15_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.056848 (rank : 124)
Query Neighborhood Hits	70	Target Neighborhood Hits	478	Shared Neighborhood Hits	19
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ANR19_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.050635 (rank : 177)
Query Neighborhood Hits	70	Target Neighborhood Hits	276	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

ANR22_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.059150 (rank : 102)
Query Neighborhood Hits	70	Target Neighborhood Hits	243	Shared Neighborhood Hits	11
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ANR23_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.060349 (rank : 99)
Query Neighborhood Hits	70	Target Neighborhood Hits	291	Shared Neighborhood Hits	19
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

ANR23_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.057497 (rank : 117)
Query Neighborhood Hits	70	Target Neighborhood Hits	296	Shared Neighborhood Hits	19
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ANR28_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.055483 (rank : 135)
Query Neighborhood Hits	70	Target Neighborhood Hits	314	Shared Neighborhood Hits	20
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR28_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.056095 (rank : 130)
Query Neighborhood Hits	70	Target Neighborhood Hits	314	Shared Neighborhood Hits	20
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR33_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.063608 (rank : 79)
Query Neighborhood Hits	70	Target Neighborhood Hits	215	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR33_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.053255 (rank : 160)
Query Neighborhood Hits	70	Target Neighborhood Hits	225	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR35_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.058876 (rank : 107)
Query Neighborhood Hits	70	Target Neighborhood Hits	784	Shared Neighborhood Hits	20
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

ANR37_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.074764 (rank : 58)
Query Neighborhood Hits	70	Target Neighborhood Hits	247	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

ANR37_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.086201 (rank : 52)
Query Neighborhood Hits	70	Target Neighborhood Hits	237	Shared Neighborhood Hits	17
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

ANR39_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.078704 (rank : 55)
Query Neighborhood Hits	70	Target Neighborhood Hits	285	Shared Neighborhood Hits	19
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANR39_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.079717 (rank : 53)
Query Neighborhood Hits	70	Target Neighborhood Hits	284	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANR41_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.089139 (rank : 49)
Query Neighborhood Hits	70	Target Neighborhood Hits	332	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

ANR42_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.062021 (rank : 85)
Query Neighborhood Hits	70	Target Neighborhood Hits	284	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANR42_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.057798 (rank : 114)
Query Neighborhood Hits	70	Target Neighborhood Hits	334	Shared Neighborhood Hits	19
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANR44_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.057613 (rank : 116)
Query Neighborhood Hits	70	Target Neighborhood Hits	318	Shared Neighborhood Hits	20
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANR46_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.088495 (rank : 50)
Query Neighborhood Hits	70	Target Neighborhood Hits	281	Shared Neighborhood Hits	18
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANR46_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.087153 (rank : 51)
Query Neighborhood Hits	70	Target Neighborhood Hits	274	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANR49_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.055490 (rank : 134)
Query Neighborhood Hits	70	Target Neighborhood Hits	282	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

ANR49_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.052541 (rank : 164)
Query Neighborhood Hits	70	Target Neighborhood Hits	285	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ANR50_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.057232 (rank : 118)
Query Neighborhood Hits	70	Target Neighborhood Hits	361	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ANR52_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.061026 (rank : 95)
Query Neighborhood Hits	70	Target Neighborhood Hits	322	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_MOUSE
θ value	θ > 10 (rank : 116)	NC score	0.061112 (rank : 94)
Query Neighborhood Hits	70	Target Neighborhood Hits	318	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANRA2_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.061660 (rank : 88)
Query Neighborhood Hits	70	Target Neighborhood Hits	288	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANRA2_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.062529 (rank : 83)
Query Neighborhood Hits	70	Target Neighborhood Hits	287	Shared Neighborhood Hits	18
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANS4B_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.070197 (rank : 65)
Query Neighborhood Hits	70	Target Neighborhood Hits	289	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ANS4B_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.076898 (rank : 56)
Query Neighborhood Hits	70	Target Neighborhood Hits	294	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ASB10_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.064174 (rank : 75)
Query Neighborhood Hits	70	Target Neighborhood Hits	291	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB10_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.061234 (rank : 91)
Query Neighborhood Hits	70	Target Neighborhood Hits	301	Shared Neighborhood Hits	19
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB11_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.050154 (rank : 181)
Query Neighborhood Hits	70	Target Neighborhood Hits	271	Shared Neighborhood Hits	16
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ASB12_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.053820 (rank : 156)
Query Neighborhood Hits	70	Target Neighborhood Hits	263	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASB12_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.054059 (rank : 152)
Query Neighborhood Hits	70	Target Neighborhood Hits	261	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASB13_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.051927 (rank : 167)
Query Neighborhood Hits	70	Target Neighborhood Hits	293	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB13_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.052287 (rank : 166)
Query Neighborhood Hits	70	Target Neighborhood Hits	293	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB16_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.055246 (rank : 137)
Query Neighborhood Hits	70	Target Neighborhood Hits	286	Shared Neighborhood Hits	19
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ASB16_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.053924 (rank : 154)
Query Neighborhood Hits	70	Target Neighborhood Hits	306	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ASB2_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.054360 (rank : 148)
Query Neighborhood Hits	70	Target Neighborhood Hits	309	Shared Neighborhood Hits	19
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ASB3_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.051614 (rank : 172)
Query Neighborhood Hits	70	Target Neighborhood Hits	316	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB3_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.056143 (rank : 128)
Query Neighborhood Hits	70	Target Neighborhood Hits	316	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB7_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.054933 (rank : 141)
Query Neighborhood Hits	70	Target Neighborhood Hits	296	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.054948 (rank : 140)
Query Neighborhood Hits	70	Target Neighborhood Hits	296	Shared Neighborhood Hits	19
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB8_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.060014 (rank : 100)
Query Neighborhood Hits	70	Target Neighborhood Hits	294	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ASB8_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.059527 (rank : 101)
Query Neighborhood Hits	70	Target Neighborhood Hits	293	Shared Neighborhood Hits	18
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

BARD1_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.057985 (rank : 111)
Query Neighborhood Hits	70	Target Neighborhood Hits	427	Shared Neighborhood Hits	19
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BARD1_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.055264 (rank : 136)
Query Neighborhood Hits	70	Target Neighborhood Hits	411	Shared Neighborhood Hits	20
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BCL3_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.058534 (rank : 109)
Query Neighborhood Hits	70	Target Neighborhood Hits	324	Shared Neighborhood Hits	20
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

BCL3_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.058915 (rank : 106)
Query Neighborhood Hits	70	Target Neighborhood Hits	388	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

CDN2D_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.068760 (rank : 69)
Query Neighborhood Hits	70	Target Neighborhood Hits	268	Shared Neighborhood Hits	14
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

CDN2D_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.058978 (rank : 105)
Query Neighborhood Hits	70	Target Neighborhood Hits	267	Shared Neighborhood Hits	14
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

CSKI1_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.056944 (rank : 122)
Query Neighborhood Hits	70	Target Neighborhood Hits	997	Shared Neighborhood Hits	34
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.058720 (rank : 108)
Query Neighborhood Hits	70	Target Neighborhood Hits	1031	Shared Neighborhood Hits	33
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI2_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.060667 (rank : 96)
Query Neighborhood Hits	70	Target Neighborhood Hits	747	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CSKI2_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.057216 (rank : 119)
Query Neighborhood Hits	70	Target Neighborhood Hits	812	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CT086_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.108626 (rank : 41)
Query Neighborhood Hits	70	Target Neighborhood Hits	277	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

DP13A_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.106985 (rank : 42)
Query Neighborhood Hits	70	Target Neighborhood Hits	107	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKG1, Q9P2B9	Gene names	APPL1, APPL, DIP13A, KIAA1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

DP13A_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.106514 (rank : 43)
Query Neighborhood Hits	70	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K3H0, Q3UJP7, Q69ZJ9, Q8BWZ8, Q8VCJ8, Q9CUW4	Gene names	Appl1, Dip13a, Kiaa1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

DP13B_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.094182 (rank : 48)
Query Neighborhood Hits	70	Target Neighborhood Hits	58	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NEU8, Q8N4R7, Q9NVL2	Gene names	DIP13B, APPL2
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

DP13B_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.102297 (rank : 45)
Query Neighborhood Hits	70	Target Neighborhood Hits	58	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K3G9, Q99LT7	Gene names	Dip13b, Appl2, Dip3b
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

EHMT1_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.054040 (rank : 153)
Query Neighborhood Hits	70	Target Neighborhood Hits	417	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

EHMT2_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.058981 (rank : 104)
Query Neighborhood Hits	70	Target Neighborhood Hits	498	Shared Neighborhood Hits	22
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT2_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.056871 (rank : 123)
Query Neighborhood Hits	70	Target Neighborhood Hits	750	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

GABP2_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.074594 (rank : 59)
Query Neighborhood Hits	70	Target Neighborhood Hits	454	Shared Neighborhood Hits	19
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

GABP2_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.074347 (rank : 61)
Query Neighborhood Hits	70	Target Neighborhood Hits	429	Shared Neighborhood Hits	19
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

GABP3_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.076514 (rank : 57)
Query Neighborhood Hits	70	Target Neighborhood Hits	330	Shared Neighborhood Hits	19
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

GMIP_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.051835 (rank : 168)
Query Neighborhood Hits	70	Target Neighborhood Hits	225	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GMIP_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.055827 (rank : 132)
Query Neighborhood Hits	70	Target Neighborhood Hits	202	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GRLF1_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.051195 (rank : 175)
Query Neighborhood Hits	70	Target Neighborhood Hits	167	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

HECD1_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.068884 (rank : 68)
Query Neighborhood Hits	70	Target Neighborhood Hits	371	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

IKBB_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.069109 (rank : 67)
Query Neighborhood Hits	70	Target Neighborhood Hits	284	Shared Neighborhood Hits	19
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

IKBB_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.079433 (rank : 54)
Query Neighborhood Hits	70	Target Neighborhood Hits	284	Shared Neighborhood Hits	19
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

INVS_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.050533 (rank : 178)
Query Neighborhood Hits	70	Target Neighborhood Hits	609	Shared Neighborhood Hits	22
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

MIB2_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.050509 (rank : 179)
Query Neighborhood Hits	70	Target Neighborhood Hits	438	Shared Neighborhood Hits	20
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

MTPN_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.069699 (rank : 66)
Query Neighborhood Hits	70	Target Neighborhood Hits	269	Shared Neighborhood Hits	17
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

MTPN_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.071706 (rank : 64)
Query Neighborhood Hits	70	Target Neighborhood Hits	269	Shared Neighborhood Hits	17
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

MYPT1_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.063283 (rank : 82)
Query Neighborhood Hits	70	Target Neighborhood Hits	723	Shared Neighborhood Hits	22
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

MYPT1_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.063995 (rank : 76)
Query Neighborhood Hits	70	Target Neighborhood Hits	539	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

MYPT2_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.057177 (rank : 120)
Query Neighborhood Hits	70	Target Neighborhood Hits	707	Shared Neighborhood Hits	23
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

OPHN1_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.111494 (rank : 40)
Query Neighborhood Hits	70	Target Neighborhood Hits	161	Shared Neighborhood Hits	11
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

OPHN1_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.121874 (rank : 39)
Query Neighborhood Hits	70	Target Neighborhood Hits	174	Shared Neighborhood Hits	13
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

PA2G6_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.059095 (rank : 103)
Query Neighborhood Hits	70	Target Neighborhood Hits	284	Shared Neighborhood Hits	19
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

PA2G6_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.054786 (rank : 142)
Query Neighborhood Hits	70	Target Neighborhood Hits	293	Shared Neighborhood Hits	19
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

PKHA1_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.097573 (rank : 46)
Query Neighborhood Hits	70	Target Neighborhood Hits	127	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.095662 (rank : 47)
Query Neighborhood Hits	70	Target Neighborhood Hits	120	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA2_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.065628 (rank : 72)
Query Neighborhood Hits	70	Target Neighborhood Hits	119	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PKHA2_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.073168 (rank : 62)
Query Neighborhood Hits	70	Target Neighborhood Hits	116	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PKHA6_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.072288 (rank : 63)
Query Neighborhood Hits	70	Target Neighborhood Hits	556	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.074462 (rank : 60)
Query Neighborhood Hits	70	Target Neighborhood Hits	591	Shared Neighborhood Hits	19
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

POTE8_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.052787 (rank : 162)
Query Neighborhood Hits	70	Target Neighborhood Hits	337	Shared Neighborhood Hits	19
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

PP16A_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.055960 (rank : 131)
Query Neighborhood Hits	70	Target Neighborhood Hits	318	Shared Neighborhood Hits	18
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

PP16B_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.051619 (rank : 171)
Query Neighborhood Hits	70	Target Neighborhood Hits	307	Shared Neighborhood Hits	18
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

PP16B_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.052697 (rank : 163)
Query Neighborhood Hits	70	Target Neighborhood Hits	302	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

PSD10_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.062286 (rank : 84)
Query Neighborhood Hits	70	Target Neighborhood Hits	301	Shared Neighborhood Hits	19
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

PSD10_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.061158 (rank : 93)
Query Neighborhood Hits	70	Target Neighborhood Hits	293	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

RAI14_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.057072 (rank : 121)
Query Neighborhood Hits	70	Target Neighborhood Hits	1367	Shared Neighborhood Hits	28
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

RAI14_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.053041 (rank : 161)
Query Neighborhood Hits	70	Target Neighborhood Hits	1505	Shared Neighborhood Hits	27
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

RBP1_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.054318 (rank : 150)
Query Neighborhood Hits	70	Target Neighborhood Hits	521	Shared Neighborhood Hits	11
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RBP1_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.055242 (rank : 138)
Query Neighborhood Hits	70	Target Neighborhood Hits	493	Shared Neighborhood Hits	11
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RGAP1_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.054969 (rank : 139)
Query Neighborhood Hits	70	Target Neighborhood Hits	189	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RGAP1_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.056377 (rank : 126)
Query Neighborhood Hits	70	Target Neighborhood Hits	185	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG05_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.054235 (rank : 151)
Query Neighborhood Hits	70	Target Neighborhood Hits	158	Shared Neighborhood Hits	5
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG05_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.054526 (rank : 145)
Query Neighborhood Hits	70	Target Neighborhood Hits	165	Shared Neighborhood Hits	6
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG06_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.054565 (rank : 144)
Query Neighborhood Hits	70	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG06_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.054577 (rank : 143)
Query Neighborhood Hits	70	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG09_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.063954 (rank : 77)
Query Neighborhood Hits	70	Target Neighborhood Hits	186	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

RHG12_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.050178 (rank : 180)
Query Neighborhood Hits	70	Target Neighborhood Hits	204	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG18_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.053908 (rank : 155)
Query Neighborhood Hits	70	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

RHG18_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.051817 (rank : 169)
Query Neighborhood Hits	70	Target Neighborhood Hits	110	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG26_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.106180 (rank : 44)
Query Neighborhood Hits	70	Target Neighborhood Hits	281	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

RR22_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.050689 (rank : 176)
Query Neighborhood Hits	70	Target Neighborhood Hits	201	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K5A4	Gene names	Rrp22
Domain Architecture	No domain graphic available
Description	Ras-like protein RRP22 (RAS-related protein on chromosome 22 homolog).

SHAN1_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.055672 (rank : 133)
Query Neighborhood Hits	70	Target Neighborhood Hits	1041	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

TAGAP_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.053477 (rank : 158)
Query Neighborhood Hits	70	Target Neighborhood Hits	82	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

TAGAP_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.050055 (rank : 182)
Query Neighborhood Hits	70	Target Neighborhood Hits	83	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

TCGAP_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.058023 (rank : 110)
Query Neighborhood Hits	70	Target Neighborhood Hits	872	Shared Neighborhood Hits	20
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCGAP_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.051804 (rank : 170)
Query Neighborhood Hits	70	Target Neighborhood Hits	409	Shared Neighborhood Hits	12
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TNKS1_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.067199 (rank : 70)
Query Neighborhood Hits	70	Target Neighborhood Hits	477	Shared Neighborhood Hits	26
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

TNKS2_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.063383 (rank : 81)
Query Neighborhood Hits	70	Target Neighborhood Hits	361	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

USH1G_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.063467 (rank : 80)
Query Neighborhood Hits	70	Target Neighborhood Hits	267	Shared Neighborhood Hits	19
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

USH1G_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.063756 (rank : 78)
Query Neighborhood Hits	70	Target Neighborhood Hits	271	Shared Neighborhood Hits	19
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

Hits sorted by NC score

SMP1L_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	70	Target Neighborhood Hits	70	Shared Neighborhood Hits	70
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SMP1L_HUMAN
NC score	0.995531 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	70	Target Neighborhood Hits	74	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMAP1_HUMAN
NC score	0.971511 (rank : 3)	θ value	8.77142e-88 (rank : 4)
Query Neighborhood Hits	70	Target Neighborhood Hits	98	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMAP1_MOUSE
NC score	0.969184 (rank : 4)	θ value	9.056e-93 (rank : 3)
Query Neighborhood Hits	70	Target Neighborhood Hits	120	Shared Neighborhood Hits	41
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

CENA1_HUMAN
NC score	0.825933 (rank : 5)	θ value	6.62687e-19 (rank : 13)
Query Neighborhood Hits	70	Target Neighborhood Hits	87	Shared Neighborhood Hits	38
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CENA2_MOUSE
NC score	0.804245 (rank : 6)	θ value	4.29542e-18 (rank : 14)
Query Neighborhood Hits	70	Target Neighborhood Hits	68	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

CENA2_HUMAN
NC score	0.800358 (rank : 7)	θ value	7.82807e-20 (rank : 9)
Query Neighborhood Hits	70	Target Neighborhood Hits	83	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

ARFG1_MOUSE
NC score	0.786040 (rank : 8)	θ value	8.38298e-14 (rank : 23)
Query Neighborhood Hits	70	Target Neighborhood Hits	51	Shared Neighborhood Hits	38
SwissProt Accessions	Q9EPJ9, Q3TI52, Q8BMM6, Q8BMQ7	Gene names	Arfgap1, Arf1gap
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

ARFG3_HUMAN
NC score	0.779946 (rank : 9)	θ value	7.58209e-15 (rank : 20)
Query Neighborhood Hits	70	Target Neighborhood Hits	56	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ARFG3_MOUSE
NC score	0.774979 (rank : 10)	θ value	3.40345e-15 (rank : 19)
Query Neighborhood Hits	70	Target Neighborhood Hits	80	Shared Neighborhood Hits	38
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ARFG1_HUMAN
NC score	0.770003 (rank : 11)	θ value	1.09485e-13 (rank : 25)
Query Neighborhood Hits	70	Target Neighborhood Hits	60	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N6T3, Q96KC4, Q96T02, Q9NSU3, Q9NVF6, Q9UIL0	Gene names	ARFGAP1, ARF1GAP
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

DDFL1_HUMAN
NC score	0.660187 (rank : 12)	θ value	7.09661e-13 (rank : 30)
Query Neighborhood Hits	70	Target Neighborhood Hits	353	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

CENG1_MOUSE
NC score	0.656702 (rank : 13)	θ value	9.56915e-18 (rank : 16)
Query Neighborhood Hits	70	Target Neighborhood Hits	531	Shared Neighborhood Hits	40
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CENG3_HUMAN
NC score	0.653730 (rank : 14)	θ value	1.74391e-19 (rank : 11)
Query Neighborhood Hits	70	Target Neighborhood Hits	455	Shared Neighborhood Hits	38
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
NC score	0.653011 (rank : 15)	θ value	2.97466e-19 (rank : 12)
Query Neighborhood Hits	70	Target Neighborhood Hits	467	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG1_HUMAN
NC score	0.649747 (rank : 16)	θ value	5.60996e-18 (rank : 15)
Query Neighborhood Hits	70	Target Neighborhood Hits	544	Shared Neighborhood Hits	41
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

NUPL_HUMAN
NC score	0.640016 (rank : 17)	θ value	3.89403e-11 (rank : 33)
Query Neighborhood Hits	70	Target Neighborhood Hits	68	Shared Neighborhood Hits	36
SwissProt Accessions	P52594, Q15277, Q4VAS0, Q4VAS1, Q4VAS3, Q53QT8, Q53R11	Gene names	HRB, RAB, RIP
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein) (Rev- interacting protein) (Rev/Rex activation domain-binding protein).

DDEF1_MOUSE
NC score	0.635607 (rank : 18)	θ value	1.63225e-17 (rank : 17)
Query Neighborhood Hits	70	Target Neighborhood Hits	592	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

NUPL_MOUSE
NC score	0.634698 (rank : 19)	θ value	3.89403e-11 (rank : 34)
Query Neighborhood Hits	70	Target Neighborhood Hits	113	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K2K6, O70448, Q8BQL5, Q8CDK9	Gene names	Hrb, Rip
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein homolog).

CENG2_MOUSE
NC score	0.631872 (rank : 20)	θ value	1.02238e-19 (rank : 10)
Query Neighborhood Hits	70	Target Neighborhood Hits	463	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

CENB1_HUMAN
NC score	0.630907 (rank : 21)	θ value	2.06002e-20 (rank : 7)
Query Neighborhood Hits	70	Target Neighborhood Hits	383	Shared Neighborhood Hits	40
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

DDFL1_MOUSE
NC score	0.629453 (rank : 22)	θ value	1.09485e-13 (rank : 26)
Query Neighborhood Hits	70	Target Neighborhood Hits	324	Shared Neighborhood Hits	39
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

CENG2_HUMAN
NC score	0.629024 (rank : 23)	θ value	3.51386e-20 (rank : 8)
Query Neighborhood Hits	70	Target Neighborhood Hits	471	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CENB5_HUMAN
NC score	0.622421 (rank : 24)	θ value	3.17815e-21 (rank : 5)
Query Neighborhood Hits	70	Target Neighborhood Hits	395	Shared Neighborhood Hits	40
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CENB2_HUMAN
NC score	0.611909 (rank : 25)	θ value	9.24701e-21 (rank : 6)
Query Neighborhood Hits	70	Target Neighborhood Hits	425	Shared Neighborhood Hits	41
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

DDEF2_HUMAN
NC score	0.608990 (rank : 26)	θ value	8.38298e-14 (rank : 24)
Query Neighborhood Hits	70	Target Neighborhood Hits	599	Shared Neighborhood Hits	41
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
NC score	0.604981 (rank : 27)	θ value	2.88119e-14 (rank : 21)
Query Neighborhood Hits	70	Target Neighborhood Hits	625	Shared Neighborhood Hits	40
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

CEND1_MOUSE
NC score	0.586895 (rank : 28)	θ value	2.43908e-13 (rank : 27)
Query Neighborhood Hits	70	Target Neighborhood Hits	260	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CEND1_HUMAN
NC score	0.586273 (rank : 29)	θ value	4.16044e-13 (rank : 29)
Query Neighborhood Hits	70	Target Neighborhood Hits	284	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

GIT2_HUMAN
NC score	0.578260 (rank : 30)	θ value	1.33837e-11 (rank : 32)
Query Neighborhood Hits	70	Target Neighborhood Hits	381	Shared Neighborhood Hits	40
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

GIT2_MOUSE
NC score	0.577279 (rank : 31)	θ value	1.02475e-11 (rank : 31)
Query Neighborhood Hits	70	Target Neighborhood Hits	323	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

CEND2_HUMAN
NC score	0.573498 (rank : 32)	θ value	1.16975e-15 (rank : 18)
Query Neighborhood Hits	70	Target Neighborhood Hits	166	Shared Neighborhood Hits	38
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

CEND3_HUMAN
NC score	0.565810 (rank : 33)	θ value	4.91457e-14 (rank : 22)
Query Neighborhood Hits	70	Target Neighborhood Hits	275	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

HRBL_HUMAN
NC score	0.564652 (rank : 34)	θ value	6.21693e-09 (rank : 37)
Query Neighborhood Hits	70	Target Neighborhood Hits	179	Shared Neighborhood Hits	41
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

CEND3_MOUSE
NC score	0.563112 (rank : 35)	θ value	3.18553e-13 (rank : 28)
Query Neighborhood Hits	70	Target Neighborhood Hits	228	Shared Neighborhood Hits	41
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

GIT1_HUMAN
NC score	0.557696 (rank : 36)	θ value	2.52405e-10 (rank : 35)
Query Neighborhood Hits	70	Target Neighborhood Hits	336	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GIT1_MOUSE
NC score	0.556524 (rank : 37)	θ value	2.52405e-10 (rank : 36)
Query Neighborhood Hits	70	Target Neighborhood Hits	341	Shared Neighborhood Hits	35
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

HRBL_MOUSE
NC score	0.533884 (rank : 38)	θ value	8.97725e-08 (rank : 38)
Query Neighborhood Hits	70	Target Neighborhood Hits	269	Shared Neighborhood Hits	39
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

OPHN1_MOUSE
NC score	0.121874 (rank : 39)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	70	Target Neighborhood Hits	174	Shared Neighborhood Hits	13
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

OPHN1_HUMAN
NC score	0.111494 (rank : 40)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	70	Target Neighborhood Hits	161	Shared Neighborhood Hits	11
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

CT086_HUMAN
NC score	0.108626 (rank : 41)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	70	Target Neighborhood Hits	277	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

DP13A_HUMAN
NC score	0.106985 (rank : 42)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	70	Target Neighborhood Hits	107	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKG1, Q9P2B9	Gene names	APPL1, APPL, DIP13A, KIAA1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

DP13A_MOUSE
NC score	0.106514 (rank : 43)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	70	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K3H0, Q3UJP7, Q69ZJ9, Q8BWZ8, Q8VCJ8, Q9CUW4	Gene names	Appl1, Dip13a, Kiaa1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

RHG26_HUMAN
NC score	0.106180 (rank : 44)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	70	Target Neighborhood Hits	281	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

DP13B_MOUSE
NC score	0.102297 (rank : 45)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	70	Target Neighborhood Hits	58	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K3G9, Q99LT7	Gene names	Dip13b, Appl2, Dip3b
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

PKHA1_HUMAN
NC score	0.097573 (rank : 46)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	70	Target Neighborhood Hits	127	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_MOUSE
NC score	0.095662 (rank : 47)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	70	Target Neighborhood Hits	120	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

DP13B_HUMAN
NC score	0.094182 (rank : 48)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	70	Target Neighborhood Hits	58	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NEU8, Q8N4R7, Q9NVL2	Gene names	DIP13B, APPL2
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

ANR41_HUMAN
NC score	0.089139 (rank : 49)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	70	Target Neighborhood Hits	332	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

ANR46_HUMAN
NC score	0.088495 (rank : 50)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	70	Target Neighborhood Hits	281	Shared Neighborhood Hits	18
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANR46_MOUSE
NC score	0.087153 (rank : 51)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	70	Target Neighborhood Hits	274	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANR37_MOUSE
NC score	0.086201 (rank : 52)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	70	Target Neighborhood Hits	237	Shared Neighborhood Hits	17
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

ANR39_MOUSE
NC score	0.079717 (rank : 53)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	70	Target Neighborhood Hits	284	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

IKBB_MOUSE
NC score	0.079433 (rank : 54)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	70	Target Neighborhood Hits	284	Shared Neighborhood Hits	19
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

ANR39_HUMAN
NC score	0.078704 (rank : 55)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	70	Target Neighborhood Hits	285	Shared Neighborhood Hits	19
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANS4B_MOUSE
NC score	0.076898 (rank : 56)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	70	Target Neighborhood Hits	294	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

GABP3_MOUSE
NC score	0.076514 (rank : 57)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	70	Target Neighborhood Hits	330	Shared Neighborhood Hits	19
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

ANR37_HUMAN
NC score	0.074764 (rank : 58)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	70	Target Neighborhood Hits	247	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

GABP2_HUMAN
NC score	0.074594 (rank : 59)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	70	Target Neighborhood Hits	454	Shared Neighborhood Hits	19
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

PKHA6_MOUSE
NC score	0.074462 (rank : 60)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	70	Target Neighborhood Hits	591	Shared Neighborhood Hits	19
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

GABP2_MOUSE
NC score	0.074347 (rank : 61)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	70	Target Neighborhood Hits	429	Shared Neighborhood Hits	19
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

PKHA2_MOUSE
NC score	0.073168 (rank : 62)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	70	Target Neighborhood Hits	116	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PKHA6_HUMAN
NC score	0.072288 (rank : 63)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	70	Target Neighborhood Hits	556	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

MTPN_MOUSE
NC score	0.071706 (rank : 64)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	70	Target Neighborhood Hits	269	Shared Neighborhood Hits	17
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

ANS4B_HUMAN
NC score	0.070197 (rank : 65)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	70	Target Neighborhood Hits	289	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

MTPN_HUMAN
NC score	0.069699 (rank : 66)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	70	Target Neighborhood Hits	269	Shared Neighborhood Hits	17
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

IKBB_HUMAN
NC score	0.069109 (rank : 67)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	70	Target Neighborhood Hits	284	Shared Neighborhood Hits	19
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

HECD1_HUMAN
NC score	0.068884 (rank : 68)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	70	Target Neighborhood Hits	371	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

CDN2D_HUMAN
NC score	0.068760 (rank : 69)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	70	Target Neighborhood Hits	268	Shared Neighborhood Hits	14
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

TNKS1_HUMAN
NC score	0.067199 (rank : 70)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	70	Target Neighborhood Hits	477	Shared Neighborhood Hits	26
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ANKR2_HUMAN
NC score	0.065740 (rank : 71)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	70	Target Neighborhood Hits	321	Shared Neighborhood Hits	19
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

PKHA2_HUMAN
NC score	0.065628 (rank : 72)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	70	Target Neighborhood Hits	119	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

ANR10_HUMAN
NC score	0.064738 (rank : 73)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	70	Target Neighborhood Hits	289	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANKR6_HUMAN
NC score	0.064589 (rank : 74)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	70	Target Neighborhood Hits	439	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ASB10_HUMAN
NC score	0.064174 (rank : 75)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	70	Target Neighborhood Hits	291	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

MYPT1_MOUSE
NC score	0.063995 (rank : 76)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	70	Target Neighborhood Hits	539	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

RHG09_HUMAN
NC score	0.063954 (rank : 77)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	70	Target Neighborhood Hits	186	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

USH1G_MOUSE
NC score	0.063756 (rank : 78)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	70	Target Neighborhood Hits	271	Shared Neighborhood Hits	19
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

ANR33_HUMAN
NC score	0.063608 (rank : 79)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	70	Target Neighborhood Hits	215	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

USH1G_HUMAN
NC score	0.063467 (rank : 80)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	70	Target Neighborhood Hits	267	Shared Neighborhood Hits	19
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

TNKS2_HUMAN
NC score	0.063383 (rank : 81)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	70	Target Neighborhood Hits	361	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

MYPT1_HUMAN
NC score	0.063283 (rank : 82)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	70	Target Neighborhood Hits	723	Shared Neighborhood Hits	22
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

ANRA2_MOUSE
NC score	0.062529 (rank : 83)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	70	Target Neighborhood Hits	287	Shared Neighborhood Hits	18
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

PSD10_HUMAN
NC score	0.062286 (rank : 84)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	70	Target Neighborhood Hits	301	Shared Neighborhood Hits	19
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANR42_HUMAN
NC score	0.062021 (rank : 85)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	70	Target Neighborhood Hits	284	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANR10_MOUSE
NC score	0.061804 (rank : 86)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	70	Target Neighborhood Hits	273	Shared Neighborhood Hits	18
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANK1_HUMAN
NC score	0.061772 (rank : 87)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	70	Target Neighborhood Hits	416	Shared Neighborhood Hits	19
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANRA2_HUMAN
NC score	0.061660 (rank : 88)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	70	Target Neighborhood Hits	288	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANK1_MOUSE
NC score	0.061611 (rank : 89)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	70	Target Neighborhood Hits	430	Shared Neighborhood Hits	19
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANKR1_MOUSE
NC score	0.061609 (rank : 90)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	70	Target Neighborhood Hits	316	Shared Neighborhood Hits	19
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ASB10_MOUSE
NC score	0.061234 (rank : 91)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	70	Target Neighborhood Hits	301	Shared Neighborhood Hits	19
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

NCOA6_MOUSE
NC score	0.061192 (rank : 92)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	70	Target Neighborhood Hits	1076	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PSD10_MOUSE
NC score	0.061158 (rank : 93)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	70	Target Neighborhood Hits	293	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANR52_MOUSE
NC score	0.061112 (rank : 94)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	70	Target Neighborhood Hits	318	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_HUMAN
NC score	0.061026 (rank : 95)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	70	Target Neighborhood Hits	322	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

CSKI2_HUMAN
NC score	0.060667 (rank : 96)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	70	Target Neighborhood Hits	747	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ANKR1_HUMAN
NC score	0.060504 (rank : 97)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	70	Target Neighborhood Hits	308	Shared Neighborhood Hits	20
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ANKR2_MOUSE
NC score	0.060370 (rank : 98)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	70	Target Neighborhood Hits	312	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANR23_HUMAN
NC score	0.060349 (rank : 99)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	70	Target Neighborhood Hits	291	Shared Neighborhood Hits	19
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

ASB8_HUMAN
NC score	0.060014 (rank : 100)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	70	Target Neighborhood Hits	294	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ASB8_MOUSE
NC score	0.059527 (rank : 101)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	70	Target Neighborhood Hits	293	Shared Neighborhood Hits	18
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ANR22_HUMAN
NC score	0.059150 (rank : 102)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	70	Target Neighborhood Hits	243	Shared Neighborhood Hits	11
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

PA2G6_HUMAN
NC score	0.059095 (rank : 103)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	70	Target Neighborhood Hits	284	Shared Neighborhood Hits	19
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

EHMT2_HUMAN
NC score	0.058981 (rank : 104)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	70	Target Neighborhood Hits	498	Shared Neighborhood Hits	22
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

CDN2D_MOUSE
NC score	0.058978 (rank : 105)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	70	Target Neighborhood Hits	267	Shared Neighborhood Hits	14
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

BCL3_MOUSE
NC score	0.058915 (rank : 106)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	70	Target Neighborhood Hits	388	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

ANR35_HUMAN
NC score	0.058876 (rank : 107)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	70	Target Neighborhood Hits	784	Shared Neighborhood Hits	20
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

CSKI1_MOUSE
NC score	0.058720 (rank : 108)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	70	Target Neighborhood Hits	1031	Shared Neighborhood Hits	33
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

BCL3_HUMAN
NC score	0.058534 (rank : 109)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	70	Target Neighborhood Hits	324	Shared Neighborhood Hits	20
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

TCGAP_HUMAN
NC score	0.058023 (rank : 110)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	70	Target Neighborhood Hits	872	Shared Neighborhood Hits	20
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

BARD1_HUMAN
NC score	0.057985 (rank : 111)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	70	Target Neighborhood Hits	427	Shared Neighborhood Hits	19
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BCL9_MOUSE
NC score	0.057975 (rank : 112)	θ value	0.163984 (rank : 41)
Query Neighborhood Hits	70	Target Neighborhood Hits	770	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

ACBD6_HUMAN
NC score	0.057891 (rank : 113)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	70	Target Neighborhood Hits	304	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANR42_MOUSE
NC score	0.057798 (rank : 114)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	70	Target Neighborhood Hits	334	Shared Neighborhood Hits	19
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

NCOA6_HUMAN
NC score	0.057666 (rank : 115)	θ value	0.21417 (rank : 43)
Query Neighborhood Hits	70	Target Neighborhood Hits	1202	Shared Neighborhood Hits	18
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

ANR44_HUMAN
NC score	0.057613 (rank : 116)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	70	Target Neighborhood Hits	318	Shared Neighborhood Hits	20
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANR23_MOUSE
NC score	0.057497 (rank : 117)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	70	Target Neighborhood Hits	296	Shared Neighborhood Hits	19
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ANR50_HUMAN
NC score	0.057232 (rank : 118)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	70	Target Neighborhood Hits	361	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

CSKI2_MOUSE
NC score	0.057216 (rank : 119)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	70	Target Neighborhood Hits	812	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

MYPT2_HUMAN
NC score	0.057177 (rank : 120)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	70	Target Neighborhood Hits	707	Shared Neighborhood Hits	23
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

RAI14_HUMAN
NC score	0.057072 (rank : 121)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	70	Target Neighborhood Hits	1367	Shared Neighborhood Hits	28
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

CSKI1_HUMAN
NC score	0.056944 (rank : 122)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	70	Target Neighborhood Hits	997	Shared Neighborhood Hits	34
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

EHMT2_MOUSE
NC score	0.056871 (rank : 123)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	70	Target Neighborhood Hits	750	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ANR15_HUMAN
NC score	0.056848 (rank : 124)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	70	Target Neighborhood Hits	478	Shared Neighborhood Hits	19
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ACBD6_MOUSE
NC score	0.056454 (rank : 125)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	70	Target Neighborhood Hits	305	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

RGAP1_MOUSE
NC score	0.056377 (rank : 126)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	70	Target Neighborhood Hits	185	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

ANKR5_HUMAN
NC score	0.056311 (rank : 127)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	70	Target Neighborhood Hits	297	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ASB3_MOUSE
NC score	0.056143 (rank : 128)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	70	Target Neighborhood Hits	316	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ANKR5_MOUSE
NC score	0.056137 (rank : 129)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	70	Target Neighborhood Hits	298	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANR28_MOUSE
NC score	0.056095 (rank : 130)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	70	Target Neighborhood Hits	314	Shared Neighborhood Hits	20
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

PP16A_MOUSE
NC score	0.055960 (rank : 131)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	70	Target Neighborhood Hits	318	Shared Neighborhood Hits	18
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

GMIP_MOUSE
NC score	0.055827 (rank : 132)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	70	Target Neighborhood Hits	202	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

SHAN1_HUMAN
NC score	0.055672 (rank : 133)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	70	Target Neighborhood Hits	1041	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ANR49_HUMAN
NC score	0.055490 (rank : 134)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	70	Target Neighborhood Hits	282	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

ANR28_HUMAN
NC score	0.055483 (rank : 135)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	70	Target Neighborhood Hits	314	Shared Neighborhood Hits	20
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

BARD1_MOUSE
NC score	0.055264 (rank : 136)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	70	Target Neighborhood Hits	411	Shared Neighborhood Hits	20
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ASB16_HUMAN
NC score	0.055246 (rank : 137)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	70	Target Neighborhood Hits	286	Shared Neighborhood Hits	19
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

RBP1_MOUSE
NC score	0.055242 (rank : 138)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	70	Target Neighborhood Hits	493	Shared Neighborhood Hits	11
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RGAP1_HUMAN
NC score	0.054969 (rank : 139)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	70	Target Neighborhood Hits	189	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

ASB7_MOUSE
NC score	0.054948 (rank : 140)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	70	Target Neighborhood Hits	296	Shared Neighborhood Hits	19
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_HUMAN
NC score	0.054933 (rank : 141)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	70	Target Neighborhood Hits	296	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

PA2G6_MOUSE
NC score	0.054786 (rank : 142)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	70	Target Neighborhood Hits	293	Shared Neighborhood Hits	19
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

RHG06_MOUSE
NC score	0.054577 (rank : 143)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	70	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG06_HUMAN
NC score	0.054565 (rank : 144)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	70	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG05_MOUSE
NC score	0.054526 (rank : 145)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	70	Target Neighborhood Hits	165	Shared Neighborhood Hits	6
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

AN13B_MOUSE
NC score	0.054437 (rank : 146)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	70	Target Neighborhood Hits	276	Shared Neighborhood Hits	17
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN36A_HUMAN
NC score	0.054427 (rank : 147)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	70	Target Neighborhood Hits	271	Shared Neighborhood Hits	17
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ASB2_HUMAN
NC score	0.054360 (rank : 148)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	70	Target Neighborhood Hits	309	Shared Neighborhood Hits	19
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

AN13B_HUMAN
NC score	0.054340 (rank : 149)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	70	Target Neighborhood Hits	265	Shared Neighborhood Hits	17
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

RBP1_HUMAN
NC score	0.054318 (rank : 150)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	70	Target Neighborhood Hits	521	Shared Neighborhood Hits	11
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RHG05_HUMAN
NC score	0.054235 (rank : 151)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	70	Target Neighborhood Hits	158	Shared Neighborhood Hits	5
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

ASB12_MOUSE
NC score	0.054059 (rank : 152)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	70	Target Neighborhood Hits	261	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

EHMT1_HUMAN
NC score	0.054040 (rank : 153)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	70	Target Neighborhood Hits	417	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

ASB16_MOUSE
NC score	0.053924 (rank : 154)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	70	Target Neighborhood Hits	306	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

RHG18_HUMAN
NC score	0.053908 (rank : 155)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	70	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

ASB12_HUMAN
NC score	0.053820 (rank : 156)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	70	Target Neighborhood Hits	263	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ANK2_HUMAN
NC score	0.053669 (rank : 157)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	70	Target Neighborhood Hits	1615	Shared Neighborhood Hits	31
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

TAGAP_HUMAN
NC score	0.053477 (rank : 158)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	70	Target Neighborhood Hits	82	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

ANK3_HUMAN
NC score	0.053458 (rank : 159)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	70	Target Neighborhood Hits	853	Shared Neighborhood Hits	29
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANR33_MOUSE
NC score	0.053255 (rank : 160)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	70	Target Neighborhood Hits	225	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

RAI14_MOUSE
NC score	0.053041 (rank : 161)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	70	Target Neighborhood Hits	1505	Shared Neighborhood Hits	27
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

POTE8_HUMAN
NC score	0.052787 (rank : 162)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	70	Target Neighborhood Hits	337	Shared Neighborhood Hits	19
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

PP16B_MOUSE
NC score	0.052697 (rank : 163)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	70	Target Neighborhood Hits	302	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

ANR49_MOUSE
NC score	0.052541 (rank : 164)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	70	Target Neighborhood Hits	285	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ANKS3_MOUSE
NC score	0.052392 (rank : 165)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	70	Target Neighborhood Hits	355	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASB13_MOUSE
NC score	0.052287 (rank : 166)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	70	Target Neighborhood Hits	293	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB13_HUMAN
NC score	0.051927 (rank : 167)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	70	Target Neighborhood Hits	293	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

GMIP_HUMAN
NC score	0.051835 (rank : 168)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	70	Target Neighborhood Hits	225	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RHG18_MOUSE
NC score	0.051817 (rank : 169)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	70	Target Neighborhood Hits	110	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

TCGAP_MOUSE
NC score	0.051804 (rank : 170)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	70	Target Neighborhood Hits	409	Shared Neighborhood Hits	12
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

PP16B_HUMAN
NC score	0.051619 (rank : 171)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	70	Target Neighborhood Hits	307	Shared Neighborhood Hits	18
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

ASB3_HUMAN
NC score	0.051614 (rank : 172)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	70	Target Neighborhood Hits	316	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

AN13C_MOUSE
NC score	0.051476 (rank : 173)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	70	Target Neighborhood Hits	242	Shared Neighborhood Hits	18
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

AN13C_HUMAN
NC score	0.051393 (rank : 174)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	70	Target Neighborhood Hits	241	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

GRLF1_HUMAN
NC score	0.051195 (rank : 175)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	70	Target Neighborhood Hits	167	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

RR22_MOUSE
NC score	0.050689 (rank : 176)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	70	Target Neighborhood Hits	201	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K5A4	Gene names	Rrp22
Domain Architecture	No domain graphic available
Description	Ras-like protein RRP22 (RAS-related protein on chromosome 22 homolog).

ANR19_HUMAN
NC score	0.050635 (rank : 177)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	70	Target Neighborhood Hits	276	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

INVS_MOUSE
NC score	0.050533 (rank : 178)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	70	Target Neighborhood Hits	609	Shared Neighborhood Hits	22
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

MIB2_HUMAN
NC score	0.050509 (rank : 179)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	70	Target Neighborhood Hits	438	Shared Neighborhood Hits	20
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

RHG12_MOUSE
NC score	0.050178 (rank : 180)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	70	Target Neighborhood Hits	204	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

ASB11_MOUSE
NC score	0.050154 (rank : 181)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	70	Target Neighborhood Hits	271	Shared Neighborhood Hits	16
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

TAGAP_MOUSE
NC score	0.050055 (rank : 182)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	70	Target Neighborhood Hits	83	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

BCL9_HUMAN
NC score	0.047868 (rank : 183)	θ value	0.279714 (rank : 44)
Query Neighborhood Hits	70	Target Neighborhood Hits	1008	Shared Neighborhood Hits	14
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

ANR25_HUMAN
NC score	0.044784 (rank : 184)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	70	Target Neighborhood Hits	350	Shared Neighborhood Hits	15
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

NSD1_HUMAN
NC score	0.041586 (rank : 185)	θ value	0.00175202 (rank : 39)
Query Neighborhood Hits	70	Target Neighborhood Hits	427	Shared Neighborhood Hits	8
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

SYNG_MOUSE
NC score	0.038194 (rank : 186)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	70	Target Neighborhood Hits	206	Shared Neighborhood Hits	10
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

DAB1_HUMAN
NC score	0.036310 (rank : 187)	θ value	0.0431538 (rank : 40)
Query Neighborhood Hits	70	Target Neighborhood Hits	219	Shared Neighborhood Hits	7
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

FOSL1_HUMAN
NC score	0.035883 (rank : 188)	θ value	0.62314 (rank : 45)
Query Neighborhood Hits	70	Target Neighborhood Hits	112	Shared Neighborhood Hits	4
SwissProt Accessions	P15407	Gene names	FOSL1, FRA1
Domain Architecture
Description	Fos-related antigen 1 (FRA-1).

HGD_HUMAN
NC score	0.026175 (rank : 189)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	70	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q93099	Gene names	HGD, HGO
Domain Architecture
Description	Homogentisate 1,2-dioxygenase (EC 1.13.11.5) (Homogentisicase) (Homogentisate oxygenase) (Homogentisic acid oxidase).

EPN2_HUMAN
NC score	0.025964 (rank : 190)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	70	Target Neighborhood Hits	156	Shared Neighborhood Hits	10
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

CBP_MOUSE
NC score	0.025275 (rank : 191)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	70	Target Neighborhood Hits	1051	Shared Neighborhood Hits	16
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

JHD3D_HUMAN
NC score	0.018496 (rank : 192)	θ value	0.21417 (rank : 42)
Query Neighborhood Hits	70	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	Q6B0I6, Q9NT41, Q9NW76	Gene names	JMJD2D, JHDM3D
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

ADNP_MOUSE
NC score	0.016931 (rank : 193)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	70	Target Neighborhood Hits	232	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z103	Gene names	Adnp
Domain Architecture
Description	Activity-dependent neuroprotector (Activity-dependent neuroprotective protein).

TTC14_HUMAN
NC score	0.013737 (rank : 194)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	70	Target Neighborhood Hits	274	Shared Neighborhood Hits	4
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

PININ_HUMAN
NC score	0.013568 (rank : 195)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	70	Target Neighborhood Hits	753	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

ADNP_HUMAN
NC score	0.011934 (rank : 196)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	70	Target Neighborhood Hits	265	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H2P0, O94881, Q9UG34	Gene names	ADNP, KIAA0784
Domain Architecture
Description	Activity-dependent neuroprotector (Activity-dependent neuroprotective protein).

TRI14_MOUSE
NC score	0.009673 (rank : 197)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	70	Target Neighborhood Hits	137	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

SDCG8_MOUSE
NC score	0.008952 (rank : 198)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	70	Target Neighborhood Hits	886	Shared Neighborhood Hits	11
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

TLE1_HUMAN
NC score	0.008737 (rank : 199)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	70	Target Neighborhood Hits	485	Shared Neighborhood Hits	8
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

TLE1_MOUSE
NC score	0.007818 (rank : 200)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	70	Target Neighborhood Hits	491	Shared Neighborhood Hits	6
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

P73L_MOUSE
NC score	0.007353 (rank : 201)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	70	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	O88898, O88897, O88899, O89097, Q8C826, Q9QWY9, Q9QWZ0	Gene names	Tp73l, P63, P73l, Trp63
Domain Architecture	No domain graphic available
Description	Tumor protein p73-like (p73L) (p63) (Transformation-related protein 63).

TBX21_MOUSE
NC score	0.006890 (rank : 202)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	70	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JKD8, Q9R0A6	Gene names	Tbx21, Tbet, Tblym
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

TRPM7_MOUSE
NC score	0.004737 (rank : 203)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	70	Target Neighborhood Hits	113	Shared Neighborhood Hits	2
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

PLCB1_MOUSE
NC score	0.004532 (rank : 204)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	70	Target Neighborhood Hits	531	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

TRDN_HUMAN
NC score	0.004439 (rank : 205)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	70	Target Neighborhood Hits	542	Shared Neighborhood Hits	7
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

PLCB1_HUMAN
NC score	0.004383 (rank : 206)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	70	Target Neighborhood Hits	614	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

NFH_HUMAN
NC score	0.002551 (rank : 207)	θ value	1.06291 (rank : 46)
Query Neighborhood Hits	70	Target Neighborhood Hits	1242	Shared Neighborhood Hits	8
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CNGA1_MOUSE
NC score	0.002422 (rank : 208)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	70	Target Neighborhood Hits	198	Shared Neighborhood Hits	3
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

KTN1_MOUSE
NC score	0.002058 (rank : 209)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	70	Target Neighborhood Hits	1324	Shared Neighborhood Hits	12
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

MAGI1_MOUSE
NC score	0.001095 (rank : 210)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	70	Target Neighborhood Hits	403	Shared Neighborhood Hits	4
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

TITIN_HUMAN
NC score	-0.002351 (rank : 211)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	70	Target Neighborhood Hits	2923	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).